arnold chiari malformation

Summary

Summary: A group of congenital malformations involving the brainstem, cerebellum, upper spinal cord, and surrounding bony structures. Type II is the most common, and features compression of the medulla and cerebellar tonsils into the upper cervical spinal canal and an associated MENINGOMYELOCELE. Type I features similar, but less severe malformations and is without an associated meningomyelocele. Type III has the features of type II with an additional herniation of the entire cerebellum through the bony defect involving the foramen magnum, forming an ENCEPHALOCELE. Type IV is a form a cerebellar hypoplasia. Clinical manifestations of types I-III include TORTICOLLIS; opisthotonus; HEADACHE; VERTIGO; VOCAL CORD PARALYSIS; APNEA; NYSTAGMUS, CONGENITAL; swallowing difficulties; and ATAXIA. (From Menkes, Textbook of Child Neurology, 5th ed, p261; Davis, Textbook of Neuropathology, 2nd ed, pp236-46)

Top Publications

  1. ncbi Chiari I malformation associated with syringomyelia: a retrospective study of 316 surgically treated patients
    Z Q Zhang
    Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, PR China
    Spinal Cord 46:358-63. 2008
  2. ncbi Treatment of the Chiari malformation with bone decompression without durotomy in children and young adults
    Hector E James
    Department of Pediatrics, Children s Hospital and University of California, San Diego, USA
    Childs Nerv Syst 18:202-6. 2002
  3. ncbi Scoliosis associated with Chiari 1 malformations: the effect of suboccipital decompression on scoliosis curve progression: a preliminary study
    Douglas Brockmeyer
    Department of Neurosurgery, University of Utah and Primary Children s Medical Center, Salt Lake City, Utah 84113 1103, USA
    Spine (Phila Pa 1976) 28:2505-9. 2003
  4. ncbi Dura-splitting decompression of the craniocervical junction: reduced operative time, hospital stay, and cost with equivalent early outcome
    Farhad M Limonadi
    Division of Pediatric Neurosurgery, Doernbecher Children s Hospital and Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosurg 101:184-8. 2004
  5. ncbi Chiari malformation: CSF flow dynamics in the craniocervical junction and syrinx
    D E Sakas
    Department of Neurosurgery, University of Athens, Evangelismos General Hospital, Athens, Greece
    Acta Neurochir (Wien) 147:1223-33. 2005
  6. ncbi Spinal anesthesia for cesarean delivery in a woman with a surgically corrected type I Arnold Chiari malformation
    Ruth Landau
    Division d Anesthésiologie, Département d Anesthésiologie, Pharmacologie et Soins Intensifs de Chirurgie APSIC, Hopitaux Universitaires de Geneve, Suisse
    Anesth Analg 97:253-5, table of contents. 2003
  7. pmc Chiari type I malformation in a pediatric population
    Leslie A Aitken
    Department of Pediatrics, University of California San Francisco, San Francisco, CA 94117 0137, USA
    Pediatr Neurol 40:449-54. 2009
  8. ncbi Osteopetrosis with Arnold Chiari malformation type I and brain stem compression
    M L Kulkarni
    Department of Pediatrics J J M Medical College, Davangere, Karnataka, India
    Indian J Pediatr 74:412-5. 2007
  9. ncbi Association of Chiari malformation type I and tethered cord syndrome: preliminary results of sectioning filum terminale
    Thomas H Milhorat
    Department of Neurosurgery, The Chiari Institute, Harvey Cushing Institutes of Neuroscience, North Shore Long Island Jewish Health System, Manhasset, NY 11030, USA
    Surg Neurol 72:20-35. 2009
  10. ncbi Syringomyelia: current concepts in pathogenesis, diagnosis, and treatment
    Clare Rusbridge
    Stone Lion Veterinary Centre, Wimbledon, London, UK
    J Vet Intern Med 20:469-79. 2006

Detail Information

Publications188 found, 100 shown here

  1. ncbi Chiari I malformation associated with syringomyelia: a retrospective study of 316 surgically treated patients
    Z Q Zhang
    Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, PR China
    Spinal Cord 46:358-63. 2008
    ..The objective of this article is to probe the surgical procedures of treatment for Chiari I malformation (CMI) associated with syringomyelia and evaluate their efficacy based on clinical and neuroradiological results...
  2. ncbi Treatment of the Chiari malformation with bone decompression without durotomy in children and young adults
    Hector E James
    Department of Pediatrics, Children s Hospital and University of California, San Diego, USA
    Childs Nerv Syst 18:202-6. 2002
    ..The purpose of this study was to provide more information on alternative operative approaches to the treatment of symptomatic Chiari type I and/or type II malformations in children and young adults...
  3. ncbi Scoliosis associated with Chiari 1 malformations: the effect of suboccipital decompression on scoliosis curve progression: a preliminary study
    Douglas Brockmeyer
    Department of Neurosurgery, University of Utah and Primary Children s Medical Center, Salt Lake City, Utah 84113 1103, USA
    Spine (Phila Pa 1976) 28:2505-9. 2003
    ..A retrospective review of the effect of suboccipital decompression and duraplasty on curve progression in 22 patients who presented with scoliosis, syringomyelia, and a Chiari 1 malformation...
  4. ncbi Dura-splitting decompression of the craniocervical junction: reduced operative time, hospital stay, and cost with equivalent early outcome
    Farhad M Limonadi
    Division of Pediatric Neurosurgery, Doernbecher Children s Hospital and Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosurg 101:184-8. 2004
    ..The authors evaluated safety, resource use, and early outcome after this surgery in patients without syringomyelia and compared the findings associated with duraplasty in patients with syringomyelia...
  5. ncbi Chiari malformation: CSF flow dynamics in the craniocervical junction and syrinx
    D E Sakas
    Department of Neurosurgery, University of Athens, Evangelismos General Hospital, Athens, Greece
    Acta Neurochir (Wien) 147:1223-33. 2005
    ..A CSF flow study in patients with Chiari malformation (ChM) who undergo craniocervical junction decompression (CCJD)...
  6. ncbi Spinal anesthesia for cesarean delivery in a woman with a surgically corrected type I Arnold Chiari malformation
    Ruth Landau
    Division d Anesthésiologie, Département d Anesthésiologie, Pharmacologie et Soins Intensifs de Chirurgie APSIC, Hopitaux Universitaires de Geneve, Suisse
    Anesth Analg 97:253-5, table of contents. 2003
    ..We report the successful management and outcome of spinal anesthesia for Cesarean delivery in a woman with a surgically corrected Arnold Chiari Type 1 malformation, a seizure disorder, and idiopathic thrombocytopenia of pregnancy...
  7. pmc Chiari type I malformation in a pediatric population
    Leslie A Aitken
    Department of Pediatrics, University of California San Francisco, San Francisco, CA 94117 0137, USA
    Pediatr Neurol 40:449-54. 2009
    ..Larger and longer-term studies are needed to determine the prognosis and optimal treatment of pediatric Chiari I...
  8. ncbi Osteopetrosis with Arnold Chiari malformation type I and brain stem compression
    M L Kulkarni
    Department of Pediatrics J J M Medical College, Davangere, Karnataka, India
    Indian J Pediatr 74:412-5. 2007
    ..The association of Type 1 Arnold Chiari malformation with osteopetrosis resulting in brain stem compression syndrome is an extremely rare entity.
  9. ncbi Association of Chiari malformation type I and tethered cord syndrome: preliminary results of sectioning filum terminale
    Thomas H Milhorat
    Department of Neurosurgery, The Chiari Institute, Harvey Cushing Institutes of Neuroscience, North Shore Long Island Jewish Health System, Manhasset, NY 11030, USA
    Surg Neurol 72:20-35. 2009
    ..The pathogenesis of CM-I is incompletely understood. We describe an association of CM-I and TCS that occurs in a subset of patients with normal size of the PCF...
  10. ncbi Syringomyelia: current concepts in pathogenesis, diagnosis, and treatment
    Clare Rusbridge
    Stone Lion Veterinary Centre, Wimbledon, London, UK
    J Vet Intern Med 20:469-79. 2006
    ..In addition, the current understanding of the painful nature of this condition is discussed and the current trends in medical and surgical management are reviewed...
  11. ncbi Paroxysmal hemicrania-tic and Chiari I malformation: an unusual association
    P Monzillo
    Department of Neurology, School of Medicine of Santa Casa of Sao Paulo, Brazil
    Cephalalgia 27:1408-12. 2007
    ..The association between CPH and TN is called chronic paroxysmal hemicrania-tic syndrome (CPH-tic). This is the first clinical description of a secondary cause of CPH-tic syndrome in the literature...
  12. doi Chiari I malformation as a cause of trigeminal neuralgia: case report
    Alexander M Papanastassiou
    Department of Neurosurgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Neurosurgery 63:E614-5; discussion E615. 2008
    ..In this article, we report the 19th case of TN associated with Chiari I malformation and review clinical outcomes and pathophysiology...
  13. ncbi Chiari 1 malformation presenting as strabismus
    Lionel Kowal
    Royal Victorian Eye and Ear Hospital and Centre for Eye Research Australia, 19 Simpson Street, East Melbourne, Victoria 3002, Australia
    Binocul Vis Strabismus Q 21:18-26. 2006
    ..Strabismus has been previously reported as a rare presenting feature of the Type 1 Chiari malformation...
  14. ncbi Retrospective study of surgery-related outcomes in patients with syringomyelia associated with Chiari I malformation: clinical significance of changes in the size and localization of syrinx on pain relief
    Masaya Nakamura
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Neurosurg 100:241-4. 2004
    ....
  15. doi Trigeminal neuralgia as the sole manifestation of an Arnold-Chiari type I malformation: case report
    Giovanni Caranci
    Department of Neurological Sciences, University of Rome La Sapienza, Rome, Italy
    Headache 48:625-7. 2008
    ..We describe the case of an adult patient who presented with symptomatic trigeminal neuralgia caused by an Arnold-Chiari type I malformation. Unlike previous cases, the malformation involved the trigeminal ophthalmic division alone...
  16. ncbi Cerebellum-small brain but large confusion: a review of selected cerebellar malformations and disruptions
    Eugen Boltshauser
    Department of Pediatric Neurology, University Children s Hospital, Zurich, Switzerland
    Am J Med Genet A 126:376-85. 2004
    ..No familial cases have been observed. Although many affected individuals have variable impairments, RS can be found in children with normal cognitive function. In this review, some of the cerebellar anomalies are briefly discussed...
  17. ncbi Chiari-like malformation with syringomyelia in the Cavalier King Charles spaniel: long-term outcome after surgical management
    Clare Rusbridge
    Stone Lion Veterinary Centre, Wimbledon Village, UK
    Vet Surg 36:396-405. 2007
    ..To evaluate long-term success of cranial cervical decompression for management of canine Chiari-like malformation with syringomyelia (CM/SM)...
  18. ncbi Surgical experience in 130 pediatric patients with Chiari I malformations
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Neurosurg 99:291-6. 2003
    ..The aim of this study was to present the long-term findings of a surgical series of pediatric patients with Chiari I malformations...
  19. ncbi Sleep disorder: a possible cause of attention deficit in children and adolescents with Chiari malformation type II
    Paulo Sérgio Azeredo Henriques Filho
    School of Medicine, Brasilia University, Brasilia, DF, Brazil
    Arq Neuropsiquiatr 67:29-34. 2009
    ..Attention deficit may be related to sleep disorders in Chiari malformation type II (CMII). Our aim is identify sleep disorders and their specific contribution in attention deficit...
  20. ncbi The role of cine flow MRI in children with Chiari I malformation
    Enrique C G Ventureyra
    Division of Neurosurgery, Children s Hospital of Eastern Ontario, University of Ottawa, 401 Smyth Road, Ottawa, Ontario, KIH 8LI Canada
    Childs Nerv Syst 19:109-13. 2003
    ..The present study attempts to analyze the role of cine flow MRI in Chiari I malformations...
  21. ncbi The natural history of the Chiari Type I anomaly
    Federica Novegno
    Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A Gemelli 1, Rome, Italy
    J Neurosurg Pediatr 2:179-87. 2008
    ..The decision of whether or not to operate is more difficult in these patients than in those with clear symptoms because of the lack of information about the natural course of this disease...
  22. ncbi The effects of posterior fossa decompressive surgery in adult patients with Chiari malformation and sleep apnea
    Ricardo Vieira Botelho
    Neurosurgical Service, Hospital do Servidor Público do Estado de São Paulo, Sao Paulo, Brazil
    J Neurosurg 112:800-7. 2010
    ..The objective of this work was to study the effect of posterior fossa decompressive surgery on respiratory parameters during sleep in patients with craniovertebral junction malformations and breathing-related sleep disorders...
  23. ncbi Posterior fossa volume in children with Chiari malformation Type I
    Spyros Sgouros
    Department of Neurosurgery and Neuroscience Informatics Laboratory of the Institute of Child Health, Birmingham Children s Hospital, Birmingham, England
    J Neurosurg 105:101-6. 2006
    ..They also investigated the role of syringomyelia in posterior fossa development...
  24. pmc Arnold Chiari type 1 malformation presenting with sleep disordered breathing in well children
    C Murray
    Children s Hospital at Westmead, Sydney, Australia
    Arch Dis Child 91:342-3. 2006
    ..Each had normal neurological examinations and an Arnold Chiari type 1 malformation was confirmed on magnetic resonance imaging. All underwent urgent posterior fossa decompression which normalised their sleep breathing...
  25. ncbi Chiari I anatomy after ventriculoperitoneal shunting: posterior fossa volumetric evaluation with MRI
    Ferdnand C Osuagwu
    Department of Anatomy, University of Ibadan, Ibadan, Nigeria
    Childs Nerv Syst 22:1451-6. 2006
    ..We aimed to evaluate if the volumetric characteristics of Chiari I after a ventriculoperitoneal shunt was due to a general volumetric reduction and if it is restricted to the posterior fossa...
  26. ncbi Foramen magnum decompression for treatment of caudal occipital malformation syndrome in dogs
    Curtis W Dewey
    Department of Neurology and Neurosurgery, Long Island Veterinary Specialists, 163 S Service Rd, Plainview, NY 11803, USA
    J Am Vet Med Assoc 227:1270-5, 1250-1. 2005
    ..Clinical signs resolved in 7 of the 14 dogs that survived, improved in 6, and did not change in 1. Results suggest that FMD may be an effective treatment for dogs with COMS, especially if performed early in the course of the disease...
  27. ncbi Posterior fossa dimension and volume estimates in pediatric patients with Chiari I malformations
    T Trigylidas
    Division of Neurosurgery, Children s Hospital of Eastern Ontario, University of Ottawa, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada
    Childs Nerv Syst 24:329-36. 2008
    ..The combination of neuroradiological and clinical findings is used to re-examine the criteria used for diagnosis and treatment of pediatric CMI patients...
  28. ncbi Chiari I malformation in the very young child: the spectrum of presentations and experience in 31 children under age 6 years
    Jeremy D W Greenlee
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Pediatrics 110:1212-9. 2002
    ..The entity of hindbrain herniation without myelodysplasia in the very young child has been poorly described. A retrospective analysis of children diagnosed with Chiari I malformation (CM I) before their sixth birthday is presented...
  29. ncbi Posterior cranial fossa box expansion leads to resolution of symptomatic cerebellar ptosis following Chiari I malformation repair
    Justin B Heller
    Division of Plastic and Reconstructive Surgery, Department of Neurosurgery, University of California, Los Angeles, California 90095, USA
    J Craniofac Surg 18:274-80. 2007
    ..One out of seven patients had return of headache in a more mild form. Thus, in our patient group the posterior fossa box reconstruction led to resolution of symptomatic cerebellar ptosis following Chiari I malformation repair...
  30. ncbi Syringomyelia in twin brothers discordant for Chiari I malformation: case report
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, USA
    J Child Neurol 19:459-62. 2004
    ....
  31. ncbi Foramen magnum cerebrospinal fluid flow characteristics in children with Chiari I malformation before and after craniocervical decompression
    Bermans J Iskandar
    Department of Neurosurgery, University of Wisconsin, Madison, Wisconsin 53792, USA
    J Neurosurg 101:169-78. 2004
    ..The authors used temporally and spatially resolved flow analyses to assess the characteristics of CSF flow in children with Chiari I malformation and the changes in these flow characteristics that occur after suboccipital decompression...
  32. ncbi Foramen magnum decompression for the treatment of Arnold Chiari malformation type I with associated syringomyelia in an elderly patient
    I Takigami
    Department of Orthopaedic Surgery, Gifu University School of Medicine, Gifu City, 501 1194, Gifu, Japan
    Spinal Cord 43:249-51. 2005
    Report of a rare case of an elderly patient with late onset of Arnold Chiari malformation type I with associated syringomyelia that was successfully treated with foramen magnum decompression.
  33. ncbi Thoracic meningocele, meningomyelocele or myelocystocele? Diagnostic difficulties, consequent implications and treatment
    M P Arts
    Department of Pediatric Neurosurgery, Erasmus Medical Center, Sophia Children Hospital, Rotterdam, The Netherlands
    Pediatr Neurosurg 40:75-9. 2004
    ..In this case report, we present a child born with a thoracic myelocystocele, the diagnostic difficulties, consequent implications and surgical treatment...
  34. ncbi Arachnoid veils and the Chiari I malformation
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, USA
    J Neurosurg 100:465-7. 2004
    ..The literature contains scant data regarding variations in anatomy at the level of the foramen of Magendie in patients with Chiari I malformation and syringomyelia...
  35. ncbi Surgical outcomes in adult patients with syringomyelia associated with Chiari malformation type I: the relationship between scoliosis and neurological findings
    Atsushi Ono
    Department of Orthopaedic Surgery, Hirosaki University School of Medicine, Japan
    J Neurosurg Spine 6:216-21. 2007
    ..In the present study of adult syringomyelia associated with Chiari malformation Type I, the authors investigated the relationships among the syrinx, scoliosis, and neurological data...
  36. ncbi Persistent syringomyelia following pediatric Chiari I decompression: radiological and surgical findings
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, USA
    J Neurosurg 100:460-4. 2004
    ..The authors have analyzed this smaller group of patients to look for possible radiological or surgical findings that may aid in predicting which patients are less likely to respond to the initial first decompressive procedure...
  37. ncbi Cluster-like headache: association with cervical syringomyelia and Arnold-Chiari malformation
    M Seijo-Martinez
    Neurology Service, Complexo Hospitalario de Pontevedra, Pontevedra, Spain
    Cephalalgia 24:140-2. 2004
  38. ncbi Effect of craniocervical decompression on peak CSF velocities in symptomatic patients with Chiari I malformation
    Maria T Dolar
    Department of Radiology, University of Wisconsin, Madison, WI, USA
    AJNR Am J Neuroradiol 25:142-5. 2004
    ..The purpose of this study was to test the hypothesis that the peak voxel velocities are decreased by craniocervical decompression...
  39. ncbi Chiari I malformation related syringomyelia: radionuclide cisternography as a predictor of outcome
    P Arora
    Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Acta Neurochir (Wien) 146:119-30. 2004
    ....
  40. ncbi Urgent surgical intervention in pediatric patients with Chiari malformation type I. Report of two cases
    John C Wellons
    Division of Neurosurgery, Section of Pediatric Neurosurgery, Children s Hospital, Birmingham, Alabama 35233, USA
    J Neurosurg 107:49-52. 2007
    ..Although seemingly rare, the clinician should consider CM-I in the differential diagnosis in pediatric patients presenting with acute brainstem or long tract signs...
  41. ncbi Arnold-Chiari malformation with syrinx presenting as carpal tunnel syndrome: a case report
    Mark J Ziadeh
    Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor 48109 0718, USA
    Arch Phys Med Rehabil 85:158-61. 2004
    ..Neurosurgical decompression led to a decrease in symptoms. A meticulous history and physical examination should be performed on patients with presumed carpal tunnel syndrome with an atypical onset of symptoms or response to therapy...
  42. ncbi Surgical results of posterior fossa decompression for patients with Chiari I malformation
    Ramon Navarro
    Division of Pediatric Neurosurgery, Children s Memorial Hospital, Northwestern University Medical School, 2300 Children s Plaza, Box 28, Chicago, IL 60614, USA
    Childs Nerv Syst 20:349-56. 2004
    ..An increasing number of children with Chiari I malformations are coming to the attention of neurosurgeons today, although a consensus on the surgical approach to these lesions has yet to be found...
  43. ncbi Relevance of surgical strategies for the management of pediatric Chiari type I malformation
    Marcelo Galarza
    Department of Neurosurgery, Children s Hospital of Turin, Turin, Italy
    Childs Nerv Syst 23:691-6. 2007
    ..In face of continuing controversy to the optimal treatment of Chiari type I malformation, the authors analyzed three different surgical strategies...
  44. ncbi Noncommunicating cysts and cerebrospinal fluid flow dynamics in am patient with a Chiari I malformation and syringomyelia--part I
    Terry Lichtor
    Department of Neurological Surgery, Rush University Medical Center, John H Stroger Hospital of Cook County and Hektoen Institute for Medical Research, Chicago, IL 60612, USA
    Spine (Phila Pa 1976) 30:1335-40. 2005
  45. ncbi Chiari Type II malformation: past, present, and future
    Kevin L Stevenson
    Children s Healthcare of Atlanta, Atlanta, Georgia, USA
    Neurosurg Focus 16:E5. 2004
    ..A thorough understanding of the embryology, anatomy, symptomatology, and surgical treatment is necessary to care optimally for children with myelomeningocele and prevent significant morbidity and mortality...
  46. ncbi Factors influencing the outcome in symptomatic Chiari I malformation
    Pankaj Arora
    Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareli Road, Lucknow 226 014, India
    Neurol India 52:470-4. 2004
    ..To study the clinico-radiological determinants of outcome in patients with Chiari I malformation (CIM)...
  47. ncbi Preoperative MRI analysis of patients with idiopathic scoliosis: a prospective study
    Masatoshi Inoue
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 30:108-14. 2005
    ..A prospective trial of preoperative MRI study in patients with "idiopathic" scoliosis...
  48. ncbi Syringobulbia in a pediatric population
    Jeremy D W Greenlee
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Neurosurgery 57:1147-53; discussion 1147-53. 2005
    ..To better understand the presentation, management, and outcome of syringobulbia in the pediatric age group...
  49. ncbi A detailed morphologic and functional magnetic resonance imaging study of the craniocervical junction in adolescent idiopathic scoliosis
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Spine (Phila Pa 1976) 32:1667-74. 2007
    ..Conventional and phase-contrast magnetic resonance (MR) imaging were used to evaluate the morphology and cerebrospinal fluid (CSF) flow dynamics at craniocervical junction in adolescent idiopathic scoliosis (AIS)...
  50. ncbi Sleep-disordered breathing in patients with Chiari malformation: improvement after surgery
    F Gagnadoux
    Department de Pneumology, Centre Hospitalier Universitaire, Angers, France
    Neurology 66:136-8. 2006
    ..In six patients with sleep apnea syndrome, PSG was repeated an average of 203 days after decompression surgery. Postoperative PSG showed a decrease in the central apnea index from 14.9 +/- 5.5 to 1.3 +/- 0.6 (p = 0.03)...
  51. ncbi Atypical syringomyelia without cavity in a patient with Chiari malformation and hydrocephalus
    Rong Wang
    Department of Spine Surgery, Drum Tower Hospital, College of Medicine, Nanjing University, Nanjing, China
    Spine (Phila Pa 1976) 32:E467-70. 2007
    ..A case report is presented...
  52. ncbi Noncommunicating cysts and cerebrospinal fluid flow dynamics in a patient with a Chiari I malformation and syringomyelia--part II
    Terry Lichtor
    Department of Neurological Surgery, Rush University Medical Center, Chicago, IL 60612, USA
    Spine (Phila Pa 1976) 30:1466-72. 2005
  53. ncbi Treatment of Chiari I malformation in patients with and without syringomyelia: a consecutive series of 66 cases
    J C Alzate
    Institute for Neurology and Neurosurgery, Singer Division, Department of Pediatric Neurosurgery, Beth Israel Medical Center, New York, New York 10128, USA
    Neurosurg Focus 11:E3. 2001
    ..Primary placement of a shunt in the presence of a sufficiently large syrinx appears to be beneficial. The question of if and when to place a shunt, however, requires further, preferably prospective, investigation...
  54. ncbi Scoliosis in children with Chiari I-related syringomyelia
    Ranjeev Bhangoo
    Department of Paediatric Neurosurgery, Birmingham Children s Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK
    Childs Nerv Syst 22:1154-7. 2006
    ..To study the relationship between scoliosis and Chiari I malformation, with reference to the possible role of cranio-vertebral decompression in preventing the need for scoliosis correction...
  55. ncbi Honored guest presentation: lifetime experiences and where we are going: Chiari I with syringohydromyelia--controversies and development of decision trees
    Arnold H Menezes
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, University of Iowa Carver College of Medicine, Iowa City, USA
    Clin Neurosurg 52:297-305. 2005
  56. ncbi Chiari I malformation accompanied by assimilation of the atlas, Klippel-Feil syndrome, and syringomyelia: case report
    Masahiro Kagawa
    Department of Neurological Surgery, Kagawa University, Miki cho, Kagawa, 761 0793, Japan
    Surg Neurol 65:497-502; discussion 502. 2006
    ..We report a case of Chiari I malformation accompanied by assimilation of the atlas, Klippel-Feil syndrome, and syringomyelia...
  57. ncbi Infratentorial hygroma
    Ignacio Arrese
    J Neurosurg 104:856-7; author reply 857. 2006
  58. ncbi A critical analysis of the Chiari 1.5 malformation
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, Alabama, USA
    J Neurosurg 101:179-83. 2004
    ..In an attempt to elucidate further the best surgical strategy and to refine the descriptive terminology, the authors retrospectively analyzed all cases at their institutions in which this form of hindbrain herniation was diagnosed...
  59. ncbi Syringomyelia with Chiari malformation; 3 unusual cases with implications for pathogenesis
    B K Owler
    Departments of Neurosurgery and Neurology, Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, Australia
    Acta Neurochir (Wien) 146:1137-43; discussion 1143. 2004
    ..These cases provide a basis for discussion of the pathogenesis and management of syringomyelia and the Chiari malformation in such cases...
  60. ncbi Trigeminal neurinoma associated with Chiari malformation and syringomyelia
    A Goel
    Department of Neurosurgery, Seth G S Medical College and King Edward VII Memorial Hospital, Parel, Mumbai, India
    J Clin Neurosci 12:608-10. 2005
    ..Within two months of tumor resection, both the Chiari malformation and the syringomyelia resolved. The association of an intracranial space-occupying lesion with Chiari malformation and syringomyelia is reviewed...
  61. ncbi Cervical myelomeningocele
    Zohreh Habibi
    Department of Neurosurgery, Children s Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran
    Neurosurgery 58:1168-75; discussion 1168-75. 2006
    ..Only a few series have been published regarding cMMC. Different issues regarding the etiology, classification, clinical, surgical, and pathological aspects of cMMC are still a matter of conflict...
  62. ncbi "Syringomyelia with Chiari malformation; 3 unusual cases with implication of pathogenesis"
    C Di Rocco
    Acta Neurochir (Wien) 147:221. 2005
  63. doi Hindbrain decompression for Chiari-syringomyelia complex: an outcome analysis comparing surgical techniques
    C Hayhurst
    Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Br J Neurosurg 22:86-91. 2008
    ..Although this is a retrospective study it suggests that bone only decompression should be reserved for patients with isolated headache...
  64. ncbi Relevance of surgical strategies for the management of paediatric Chiari type I malformation
    Ramon Navarro
    Childs Nerv Syst 23:725-6; author reply 727. 2007
  65. ncbi Surgical prognosis in hindbrain related syringomyelia
    S Asgari
    Department of Neurosurgery, University Hospital Essen, Hufelandstr 55, Essen, Germany
    Acta Neurol Scand 107:12-21. 2003
    ..The recommended operative treatment against hindbrain related syringomyelia is suboccipital decompression. The aim of the study was to define prognostic factors for surgical outcome in this disease...
  66. ncbi Treatment of Chiari malformation, syringomyelia and hydrocephalus by neuroendoscopic third ventriculostomy
    N Buxton
    Department of Neurosurgery, University Hospital Nottingham, UK
    Minim Invasive Neurosurg 45:231-4. 2002
    ..Two similar cases are discussed. The technique is advocated for the treatment of such complex dysraphic conditions...
  67. ncbi Curve progression in scoliosis associated with Chiari I malformation following suboccipital decompression
    Frances A Farley
    Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, USA
    J Spinal Disord Tech 15:410-4. 2002
    ..Eight also had syringomyelia. Despite initial curve stabilization, at final follow-up eight curves were of the magnitude to require spinal fusion. Neither bracing nor secondary neurosurgical procedures arrested progressive curves...
  68. ncbi Cranio-cervical decompression for Chiari type I-malformation, adding extreme lateral foramen magnum opening and expansile duroplasty with arachnoid preservation. Technique and long-term functional results in 44 consecutive adult cases -- comparison with l
    M Sindou
    Department of Neurosurgery, Hopital Neurologique Pierre Wertheimer, University of Lyon, Lyon, France
    Acta Neurochir (Wien) 144:1005-19. 2002
    ..2. and to compare this technical modality with the other modalities reported in the literature...
  69. ncbi The Chiari I malformation and the neurotologist
    Arvind Kumar
    Department of Otolaryngology, Head and Neck Surgery, University of Illinois at Chicago, 60612, USA
    Otol Neurotol 23:727-35. 2002
    ..The second objective is to report how the results of a vestibular evaluation can help neurosurgeons decide on the need for surgical treatment...
  70. ncbi Endoscopic third ventriculostomy for treatment of noncommunicating syringomyelia associated with a Chiari I malformation and hydrocephalus: case report and pathophysiological considerations
    Philippe Metellus
    Department of Neurosurgery, Timone Hospital, Marseille, France
    Neurosurgery 51:500-3; discussion 503-4. 2002
    ..The successful use of this technique in such a case has not been previously described, and the results allow us to speculate on the pathophysiological mechanism involved...
  71. doi Craniocervical junction fusions in patients with hindbrain herniation and syringohydromyelia
    Albert J Fenoy
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
    J Neurosurg Spine 9:1-9. 2008
    ..The authors surveyed the indications for CCJ fusions in this population...
  72. ncbi [Syringomyelia and Chiari's malformation in a child with scoliosis]
    A Weijenberg
    Universitair Medisch Centrum Groningen, Groningen
    Ned Tijdschr Geneeskd 152:1339-43. 2008
    ..In children with structural scoliosis, ancillary investigation in the way of neuroimaging of the spinal cord should be considered to exclude underlying spinal cord pathology, even in the absence of neurological abnormalities...
  73. ncbi Chiari I malformation associated with syringomyelia and scoliosis: a twenty-year review of surgical and nonsurgical treatment in a pediatric population
    James M Eule
    Department of Orthopedic Surgery, University of Colorado, Denver, Colorado, USA
    Spine (Phila Pa 1976) 27:1451-5. 2002
    ..Retrospective review of patients with Chiari I malformation with or without associated scoliosis...
  74. ncbi Relationship of cine phase-contrast magnetic resonance imaging with outcome after decompression for Chiari I malformations
    Matthew J McGirt
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    Neurosurgery 59:140-6; discussion 140-6. 2006
    ..We examined whether or not cerebrospinal fluid (CSF) flow dynamics assessed by cine phase contrast magnetic resonance imaging could independently predict response to posterior fossa decompression for Chiari I malformations...
  75. doi Comparison of posterior fossa decompression with and without duraplasty for the surgical treatment of Chiari malformation Type I in pediatric patients: a meta-analysis
    Susan R Durham
    Department of Surgery Pediatric Neurosurgery, Dartmouth Medical School, Hanover, NH, USA
    J Neurosurg Pediatr 2:42-9. 2008
    ..The objective of this meta-analysis was to compare the outcome of posterior fossa decompression with duraplasty (PFDD) and posterior fossa decompression without duraplasty (PFD) for the treatment of CM-I in children...
  76. doi Acute external hydrocephalus complicating craniocervical decompression for syringomyelia-Chiari I complex: case report and review of the literature
    Paolo Perrini
    Department of Neurosurgery, Hope Hospital, Salford, Manchester, UK
    Neurosurg Rev 31:331-5. 2008
    ....
  77. doi Initial management of hydrocephalus associated with Chiari malformation Type I-syringomyelia complex via endoscopic third ventriculostomy: an outcome analysis
    Caroline Hayhurst
    Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    J Neurosurg 108:1211-4. 2008
    ..The aim of this study was to evaluate the efficacy of endoscopic third ventriculostomy (ETV) in patients with Chiari malformation Type I (CM-I) and hydrocephalus with or without syringomyelia...
  78. doi Time course of syringomyelia resolution following decompression of Chiari malformation Type I
    Nicholas M Wetjen
    Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA
    J Neurosurg Pediatr 1:118-23. 2008
    ....
  79. ncbi Presyrinx in children with Chiari malformations
    S Goh
    School of Medicine, University of California San Francisco, San Francisco, CA 94143, USA
    Neurology 71:351-6. 2008
    ..Only three pediatric cases have been reported previously. We describe the clinical and radiologic features of presyrinx in six pediatric patients...
  80. ncbi Chiari malformation, cervical disc prolapse and syringomyelia--always think twice
    Jonathon R Ball
    Department of Neurosurgery, Royal North Shore Hospital, Pacific Highway, St Leonards, 2065 New South Wales, Australia
    J Clin Neurosci 15:474-6. 2008
    ..Chiari I malformations are increasingly incidentally detected and asymptomatic. This first report of arthroplasty for cervical spondylosis associated with syringomyelia adds to the growing body of experience with this new technology...
  81. ncbi Ultrastructural pathology of Golgi apparatus of nerve cells in human brain edema associated to brain congenital malformations, tumours and trauma
    O J Castejon
    Institute of Biological Investigations, Faculty of Medicine, University of Zulia, Maracaibo, Venezuela
    J Submicrosc Cytol Pathol 31:203-13. 1999
    ..The ischemia and anoxia associated to the vasogenic and cytotoxic brain edema induced enlargement, fragmentation and disappearance of stacked Golgi cisternae...
  82. ncbi Prevalence of neural axis abnormalities in patients with infantile idiopathic scoliosis
    Matthew B Dobbs
    Department of Orthopaedic Surgery, Washington University School of Medicine, Saint Luis, Missouri 63110, USA
    J Bone Joint Surg Am 84:2230-4. 2002
    ..In two previous studies involving a total of only ten patients with infantile idiopathic scoliosis, five patients were noted to have a neural axis abnormality on magnetic resonance images...
  83. ncbi [Surgical management of syringomyelia associated with Arnold-Chiari malformation, primary IgA deficiency and chromosomal abnormality--a case report]
    A Keyaki
    Dpartment of Neurosurgery and Neurology, Tenri Hospital, Nara, Japan
    Nihon Geka Hokan 59:161-7. 1990
    ..The association of these three anomalies is very rare and genetical relationship is not known. From surgical point of view, it is conceivable that preoperative management in a case of asymptomatic IgA deficiency is uneventful...
  84. ncbi Spondylolysis associated with Arnold-Chiari malformation and syringomyelia. A report of two cases
    J D Bowen
    Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA
    Spine (Phila Pa 1976) 22:2458-63. 1997
    ..e., Arnold-Chiari malformation Type I)...
  85. ncbi Auditory brainstem response abnormalities and hearing loss in children with craniosynostosis
    Michael W Church
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA
    Pediatrics 119:e1351-60. 2007
    ..Our objective was to evaluate such patients for auditory brainstem response and hearing disorders with the long-term goal of improving patient evaluation and management...
  86. ncbi [Platybasia, basilar groove, odontoid process and kinking of the brainstem: a common etiology with idiopathic syringomyelia, scoliosis and Chiari malformations]
    M B Royo-Salvador
    Servicio de Neurocirugia, Clinica Tres Torres, Barcelona, Espanña
    Rev Neurol 24:1241-50. 1996
    ..Confirmation is based on an abnormally low position of the conus medullaris (CMB) in the patients with SMI...
  87. ncbi Bilateral congenital vocal cord paralysis: a 16-year institutional review
    R Christopher Miyamoto
    Department of Otolaryngology and Communication Disorders, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
    Otolaryngol Head Neck Surg 133:241-5. 2005
    ..To review the management and outcome of bilateral congenital true vocal cord paralysis in 22 patients treated over a 16-year period and to review the role of tracheostomy in these patients...
  88. ncbi In utero repair of myelomeningocele: experimental pathophysiology, initial clinical experience, and outcomes
    Diana L Farmer
    Departments of Surgery and Neurosurgery and the Fetal Treatment Center, University of California, San Francisco, CA 94143 0570, USA
    Arch Surg 138:872-8. 2003
    ..Experimental work raises the possibility that in utero repair of myelomeningocele (MMC) may improve lower extremity, bladder, and bowel function, ameliorate the Arnold-Chiari malformation, and decrease the need for postnatal shunting...
  89. ncbi Axillary vein thrombosis as a manifestation of rapidly progressive neuropathic arthropathy of the shoulder associated with syringomyelia
    Antonio G Tristano
    Department of Internal Medicine, Hospital Dr Domingo Luciani, Caracas, Venezuela
    Mayo Clin Proc 80:416-8. 2005
    ..To our knowledge, this is the first report of a patient with this constellation of findings...
  90. ncbi [A new surgical treatment for syringomyelia, scoliosis, Arnold-Chiari malformation, kinking of the brainstem, odontoid recess, idiopathic basilar impression and platybasia]
    M B Royo Salvador
    , , Barcelona, Jefe del,
    Rev Neurol 25:523-30. 1997
    ..on medullary traction as responsible for idiopathic syringomyelia (SMI), idiopathic scoliosis (ESCID), Arnold Chiari malformation (ARCH), platybasia (PTB), basilar impression (IMB), odontoid recess (RTO) kinking of the brain stem (KTC)..
  91. ncbi Blepharoclonus and Arnold-Chiari malformation
    D E Jacome
    Department of Medicine, Franklin Medical Center, 164 High Street, Greenfield, Massachusetts 01301, USA
    Acta Neurol Scand 104:113-7. 2001
    ..BLC may follow major head trauma. Four patients with Arnold-Chiari malformation (ACM) and BLC are described...
  92. doi [Tinnitus treatment: neurosurgical management]
    A Londero
    Service d ORL et de chirurgie cervicofaciale, Hopital Europeen Georges Pompidou, 75908 Paris Cedex 15, France
    Neurochirurgie 55:248-58. 2009
    ..However, in the near future better knowledge of tinnitus pathophysiology and innovative therapeutic tools could emerge from neuromodulation techniques such as repeated transcranial magnetic or epidural electric stimulation...
  93. ncbi Emergence of oropharyngeal, laryngeal and swallowing activity in the developing fetal upper aerodigestive tract: an ultrasound evaluation
    Jeri L Miller
    Department of Rehabilitation Medicine, Physical Disabilities Branch, Room S6235, Building 10, Warren G Magnuson Clinical Center, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Early Hum Dev 71:61-87. 2003
    ..controls were compared to seven cases at risk for postnatal feeding and swallowing dysfunction (Type II Arnold Chiari Malformation, trisomy 18, polyhydramnios, intrauterine growth restriction, Brachmann-de Lange Syndrome)...
  94. doi Neuropathic arthropathy progressing with multiple joint involvement in the upper extremity due to syringomyelia and type I Arnold-Chiari malformation
    Baris Nacir
    2nd Department of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ministry of Health, 06340, Cebeci, Ankara, Turkey
    Rheumatol Int 30:979-83. 2010
    ..The characteristics of this presented case is the presence of Arnold-Chiari malformation accompanying with syringomyelia and involvement of the shoulder, elbow and hand (multiple joint involvement)...
  95. ncbi Headache in Ehlers-Danlos syndrome
    D E Jacome
    Franklin Medical Center, Department of Medicine, Greenfield, MA, USA
    Cephalalgia 19:791-6. 1999
    ..The clinical data collected on 18 patients with EDS and chronic headaches is reported...
  96. ncbi [Clinico-epidemiologic study of infantile hydrocephalus in Japan]
    T Negoro
    Department of Pediatrics, Nagoya
    No To Hattatsu 26:211-5. 1994
    ..3) Clinico-epidemiologic features of intractable hydrocephalus based on the diagnostic criteria of the research committee was investigated comparing intractable with non-intractable groups.(ABSTRACT TRUNCATED AT 250 WORDS)..
  97. ncbi Relation between intracranial volume and the surface area of the foramen magnum
    Niyazi Acer
    School of Health Sciences, Mugla University, Mugla, Turkey
    J Craniofac Surg 17:326-30. 2006
    ..The cephalometry could apply on living subjects and, thereby, our findings could provide some data to evaluate the etiology of Arnold Chiari malformation and achondroplasia for living subjects.
  98. pdf The value of transcranial cerebral sonography in diagnosing neurootological disorders
    Joel F Lehrer
    Holy Name Hospital, Teaneck, New Jersey, USA
    Int Tinnitus J 15:164-7. 2009
    ..Furthermore, TCCS is a valuable addition to neurootologists' test batteries...
  99. doi Cranial malformations in related white lions (Panthera leo krugeri)
    F E Scaglione
    Dipartimento di Patologia Animale, Universita degli Studi di Torino, Via L da Vinci 44, 10095 Grugliasco, Italy
    Vet Pathol 47:1095-9. 2010
    ..Paternal consanguinity of the parents, along with inbreeding among white lions in general, could account for the high incidence of congenital malformations of the head in this pride of white lions...
  100. ncbi Congenital vocal cord paralysis
    Mehmet Ada
    Otolaryngology Head and Neck Surgery Department, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey
    J Craniofac Surg 21:273-4. 2010
    ..In this article, we report 2 patients with idiopathic congenital vocal cord paralysis. One of them has the unilateral vocal cord paralysis, and the other, bilateral...
  101. ncbi [Our experience with the programmable Codman-Medos valve: review of 125 shunts]
    G Catalan
    Servicio de Neurocirugia, Hospital de Cruces, Plaza de Cruces, s n E 48903 Barakaldo, Vizcaya
    Rev Neurol 31:1136-42. 2000
    ..Programmable valves are a possible solution in cases of excessive or insufficient draining...

Research Grants38

  1. Diffusion Tensor Imaging of Wallerian Degeneration in MS
    Khader Hasan; Fiscal Year: 2009
    ..This tool will also help in the fusion of multi-modal MRI data for a robust segmentation of the subregions of CC and 1C. The DTI measures, after accounting for the age and gender dependence will be correlated with the clinical measures. ..
  2. Noninvasive Measurements of Intracranial Pressure
    Noam Alperin; Fiscal Year: 2004
    ..3. Quantify and demonstrate improved reproducibility of the volumetric flow rates and the resulting ICP values. ..
  3. Development and Early Clinical Evaluation of Noninvasive MRI Measurement of ICP
    Noam Alperin; Fiscal Year: 2008
    ..Preliminary results demonstrated lesser inter-individual variability of the normalized tCBF measurement. ..
  4. Development and Early Clinical Evaluation of Noninvasive MRI Measurement of ICP
    Noam Alperin; Fiscal Year: 2006
    ..Preliminary results demonstrated lesser inter-individual variability of the normalized tCBF measurement. ..
  5. Multicenter Trial of Fetal Myelomeningocele Repair
    Diana Farmer; Fiscal Year: 2007
    ..In summary, the proposed trial will be able to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
  6. Folic Acid Enhances Repair Mechanism in the Adult CNS
    Bermans Iskandar; Fiscal Year: 2008
    ....
  7. PENNSYLVANIA ABUSIVE HEAD TRAUMA PREVENTION PROGRAM
    Mark Dias; Fiscal Year: 2007
    ....
  8. In Vivo CSF Shunt Hydrodynamics in Hydrocephalus
    Marvin Bergsneider; Fiscal Year: 2008
    ..Documenting definitive evidence of the tuned-dynamic absorber model could have fundamental implications to all ICP disorders. ..
  9. In Vivo Imaging of Post-Traumatic Cerebral Amyloid Deposition
    Marvin Bergsneider; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  10. Diffusion Tensor Imaging of Wallerian Degeneration in MS
    Khader Hasan; Fiscal Year: 2008
    ..The DTI measures, after accounting for the age and gender dependence will be correlated with the clinical measures. ..
  11. Multicenter Trial of Fetal Myelomeningocele Repair
    N Adzick; Fiscal Year: 2007
    ..In summary, the proposed trial will be able to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
  12. Folic Acid Enhances Repair Mechanism in the Adult CNS
    Bermans J Iskandar; Fiscal Year: 2010
    ....
  13. In Vivo CSF Shunt Hydrodynamics in Hydrocephalus
    Marvin Bergsneider; Fiscal Year: 2010
    ..Documenting definitive evidence of the tuned-dynamic absorber model could have fundamental implications to all ICP disorders. ..
  14. Folic Acid Enhances Repair Mechanism in the Adult CNS
    Bermans Iskandar; Fiscal Year: 2009
    ....
  15. In Vivo CSF Shunt Hydrodynamics in Hydrocephalus
    Marvin Bergsneider; Fiscal Year: 2009
    ..Documenting definitive evidence of the tuned-dynamic absorber model could have fundamental implications to all ICP disorders. ..
  16. Multicenter Trial of Fetal Myelomeningocele Repair
    N Adzick; Fiscal Year: 2008
    ..In summary, the proposed trial will be able to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
  17. Multicenter Trial of Fetal Myelomeningocele Repair
    Diana Farmer; Fiscal Year: 2008
    ..In summary, the proposed trial will be able to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
  18. PENNSYLVANIA ABUSIVE HEAD TRAUMA PREVENTION PROGRAM
    Mark Dias; Fiscal Year: 2008
    ....
  19. Diffusion Tensor Imaging of Wallerian Degeneration in MS
    Khader Hasan; Fiscal Year: 2007
    ..The DTI measures, after accounting for the age and gender dependence will be correlated with the clinical measures. ..
  20. Folic Acid Enhances Repair Mechanism in the Adult CNS
    Bermans Iskandar; Fiscal Year: 2007
    ....
  21. BAEP SCREENING OF NEONATES EXPOSED TO ALCOHOL/COCAINE
    MICHAEL CHURCH; Fiscal Year: 1999
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  22. A HEMODYNAMIC MODEL OF INTRACRANIAL PRESSURE DYNAMICS
    Marvin Bergsneider; Fiscal Year: 2000
    ..An improved understanding of these disorders will offer new and better treatment modalities for millions of affected patients. ..
  23. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2000
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  24. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2000
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  25. A HEMODYNAMIC MODEL OF INTRACRANIAL PRESSURE DYNAMICS
    Marvin Bergsneider; Fiscal Year: 2001
    ..An improved understanding of these disorders will offer new and better treatment modalities for millions of affected patients. ..
  26. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2001
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  27. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2001
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  28. Multicenter Trial of Fetal Myelomeningocele Repair
    N Adzick; Fiscal Year: 2002
    ..In summary, the proposed trial is expected to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
  29. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2001
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  30. A HEMODYNAMIC MODEL OF INTRACRANIAL PRESSURE DYNAMICS
    Marvin Bergsneider; Fiscal Year: 2002
    ..An improved understanding of these disorders will offer new and better treatment modalities for millions of affected patients. ..
  31. Folic Acid Enhances Repair Mechanism in the Adult CNS
    Bermans Iskandar; Fiscal Year: 2006
    ....
  32. Multicenter Trial of Fetal Myelomeningocele Repair
    N Adzick; Fiscal Year: 2006
    ..In summary, the proposed trial is expected to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
  33. Multicenter Trial of Fetal Myelomeningocele Repair
    Diana Farmer; Fiscal Year: 2006
    ..In summary, the proposed trial is expected to demonstrate whether fetal intervention offers improved outcome with a reasonable quality of life for spina bifida children. ..
  34. Diffusion Tensor Imaging of Wallerian Degeneration in MS
    Khader Hasan; Fiscal Year: 2006
    ..The DTI measures, after accounting for the age and gender dependence will be correlated with the clinical measures. ..
  35. In Vivo CSF Shunt Hydrodynamics in Hydrocephalus
    Marvin Bergsneider; Fiscal Year: 2007
    ..Documenting definitive evidence of the tuned-dynamic absorber model could have fundamental implications to all ICP disorders. ..
  36. Folic Acid Enhances Repair Mechanism in the Adult CNS
    Bermans Iskandar; Fiscal Year: 2009
    ....