cerebral ventricle neoplasms

..This review aims to clarify the specific role of neurosurgeons in the multidisciplinary management of SGCTs in children with TSC...

..Despite benign histological features and a reported favorable postoperative course, there is still limited clinical experience with this tumor...

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..This report will help provide better characterization of this entity, improving the diagnosis and potentially reducing mortality in RGTFV...

..The astrocytic component showed characteristic features of a pilocytic astrocytoma, as is often the case in the fourth ventricle examples...

..Rosette-forming glioneuronal tumor is a newly described mixed glial and neuronal tumor. We describe two cases and review the literature to better characterize this entity...

..These tumors are relatively infrequent lesions, and because of that, they can be challenging to diagnose for the practicing pathologist. In this article, we summarize the clinical and pathologic findings of these new lesions...

..A review of the clinical features and courses of all 21 cases is presented and management recommendations are given...

..Nevertheless, the case here reported, like in 6 of the 12 cases in literature, developed disabling post-operative deficits. To establish the therapeutic choice long-term follow-up studies are needed...

..We describe the clinical and pathologic features of two patients with rare rosette-forming glioneuronal tumors of the fourth ventricle, one of which was associated with dysgenetic tricho-rhinopharyngeal type I syndrome...

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..The authors describe the first reported occurrence of fourth ventricular subependymoma in a father and son, suggesting the possibility of direct inheritance...

..Subependymomas are rare ependymal neoplasms. To date, a large clinicopathologic study of these benign neoplasms treated with modern neurosurgical techniques has not been reported...

..Compared with other ependymal tumors, subependymomas have the lowest rate of cell proliferation as evidenced by MIB-1 immunostaining...

..However, the clinical data available including the cases presented here, along with the histological features, suggest that these are low grade tumours with a good prognosis after surgical resection...

..Endoscopic resection of solid tumors appears feasible in select patients and warrants further evaluation...

..Cavernomas should be considered in the differential diagnosis of third ventricular lesions. Ventriculoscopy is very useful in establishing the diagnosis...

..The current treatment plan includes gross total resection followed by radiologic surveillance. Repeat resection or radiation treatment will be recommended in the event of recurrence...

..The clinical presentation is variable but they tend to occur mostly in adults. There is only one report of a chordoid glioma in a 12 year old child...

..This paper is intended to be an update of our earlier published work on CNS tumors along with additional information on intraventricular tumors. Three cases of central neurocytoma are also discussed...

..The differences in behaviour and prognosis between medulloblastoma and cerebellar liponeurocytoma are presented with the corresponding implications for management...

..Surgical resection is the recommended treatment. Meticulous baseline and ongoing neurological assessments are of paramount importance in the care of a patient with a colloid cyst to promote optimal patient outcomes...

..Although emergent external ventricular drainage was performed, the patient died. In this report, the authors review the literature and discuss the clinical features and treatment of pilomyxoid astrocytoma...

..The method described here reflects the combination of the frontal interhemispheric and trans-lamina terminalis approaches...

..The histological diagnosis was of central neurocytoma but the lesion showed a fairly elevated Ki-67 index (6%). Given this finding, close neuroimaging monitoring was performed and at the moment the patient is free of recurrence...

..We made a retrospective study of patients with these lesions and analyzed the clinical findings, radiological features and especially the surgical treatment on the basis of surgical approaches and techniques...

..In this retrospective review, we report our long-term follow-up during a 13-year period in 35 patients who underwent endoscopic resection of colloid cysts...

..In this study, we report a metachronous occurrence of choroid plexus papilloma and medulloblastoma in the same patient, which has not been reported before to the best of our knowledge...

..This special case helps increase our understanding of benign CPPs and expands our differential diagnostic consideration of lesions with similar manifestations...

..Ectopic craniopharyngioma is an uncommon entity. We report the first case of ectopic craniopharyngioma confined purely within the fourth ventricle, exophytic from pons...

..Because patients with TS may not report visual loss, they should undergo periodic ophthalmologic screening...

..To date, follow-ups of both patients have involved no adjuvant therapy, and there have been no signs of tumor recurrence on magnetic resonance images. The nature, radiological findings, and treatments of these tumors are discussed...

..Most of these are associated with hydrocephalus requiring a cerebrospinal fluid diversion procedure. The present study aims to assess the effectiveness of endoscopic biopsy and third ventriculostomy (ETV) in these patients...

..Detailed anatomic analysis with pathophysiological consideration substantiated the excellent result of minimally invasive endoscopic surgery for lipoma removal...

..We decided to treat colloid cysts with endoscopic approach since 1999. In this paper we present our results in 6 consecutive cases admitted at our institution from 1999 to 2004...

..Outcome is often favorable when the tumor is completely removed. In some patients the clinical course is more aggressive and additional treatment such as radiotherapy, radiosurgery or chemotherapy is needed...

..The aim of the present study was to elucidate whether intracranial air after intraventricular surgery could be alleviated safely using CO2, and investigate its clinical usefulness...

..Both differences and similarities of the 2 techniques with their advantages and pitfalls were analyzed in detail. The developing trends in the near future were also discussed...

..Spontaneous brain hemorrhage in a full-term infant requires a diligent and persistent search to rule out an underlying neoplasm...

..It can be used alone to achieve gross total removal or marsupialization of cystic tumors, or, more often, in association with additional therapies, such as microsurgery, radiosurgery or intracavitary drug administration...

..Total resection of choroid plexus tumors in the fourth ventricle is difficult because of invasion into the fourth ventricle floor. Adjuvant therapy for choroid plexus tumors with brain stem infiltration must be established...

..Ventricular schwannomas are very uncommon. We report such a tumor in the right lateral ventricle of a 16-year-old young man. The various etiopathogenic hypotheses are discussed...

..Two illustrative cases in which the authors report preliminary results about molecular analysis of some genetic markers are described...

..Neuroradiological and anatomopathological features of subependymoma are discussed...

..This tumor resembled those derived from circumventricular organs. Its localization in the area postrema region led us to hypothesize that it may be derived from this circumventricular organ...

..RESULTS AND CONCLUSIONS: Fourth ventricular neurocytoma is rare and has only been reported twice previously. It appears most likely that this tumour arises from subependymal progenitor cell lines...

..This approach minimizes the distance between the tumor and the surgeon, while maximizing neural preservation. We think this is the definitive approach to this difficult region of the posterior fossa...

..The association of ventricular diverticula with intra- and paraventricular tumors causing obstructive hydrocephalus has rarely been reported...

..Total tumor excision is associated with favorable prognoses. Postoperative radiotherapy may be considered for cases of subtotal excision, anaplastic histological variants, or recurrent tumors...

..Imaging criteria of medulloblastomas and ependymomas were defined retrospectively to allow a preoperative differential diagnosis of these malignant tumors of the posterior fossa...

..Our study supports the beneficial effect of radiation therapy in the management of these tumours...

..This provides a proper 3-dimensional imaging insight to the pathological anatomy and sets a new dimension in collaboration for training and education...

..Distinctive imaging features are its location, ovoid shape, hyperdensity on CT scans, and uniform intense contrast enhancement...

..However, because of their benign histology, partial resection seems to carry a similar prognosis as tumors in other locations that are amenable to complete resection...

..We report a patient presenting with hydrocephalus secondary to a posterior third ventricular plasma-cell lesion which exhibited delayed transudation of contrast medium into the adjacent aqueduct and fourth ventricle...

..The background, clinical features, treatment and outcomes are presented and discussed. We speculate on the association of these two conditions and propose possible explanations for the clinical features...

..To investigate the diagnostic method and analyze the result of microneurosurgical treatment for tumors of the fourth cerebral ventricle...

..Prospective monitoring of treated patients with MRI coupled with judicious use of radiosurgery will likely further decrease treatment-related morbidity...

..A case of central neurocytoma with peritoneal dissemination is presented...

..For lesions that are truly in the posterior third ventricle without extension posterior to the splenium, we prefer the interhemispheric-transcallosal approach in the lateral position...

..Fewer than 20 cases have been reported in the literature, all but three in females. This paper describes a 54-year-old man with a chordoid glioma and reviews the clinicopathological features of this lesion...

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..The trans-lamina terminalis approach provides a suitable route for an early control of this attachment under direct vision, allowing a safe dissection of the mass from the third ventricle...

..The imaging and histopathological features are reviewed. The immunopositivity allows a diagnosis of neurocytoma. Prognosis is favorable following total surgical resection, with low recurrence rate...

..Low-grade marginal zone B-cell, T-cell and high-grade diffuse large B-cell (present case) forms have been described. With a proper adjuvant therapy a relatively good outcome is observed...

..In addition, this study demonstrates the feasibility and usefulness of in situ proximity ligation assay for monitoring receptor tyrosine kinase activation in formalin-fixed, paraffin-embedded, archival tissues...

..Overall, this paper reviews the findings of the larger studies and highlights some of the important case reports that contribute to the current management of central neurocytomas...

..Piecemeal removal of the tumor can be safely and easily performed and special attention should be paid to the choroidal vessels intraoperatively...

..After receiving combination treatment with surgery, stereotactic radiosurgery, and a chemotherapy regimen including high-dose methotrexate, the patient had a disease-free survival of 18 months...

..2-2.0% of all brain lesions. Transcallosal, transforaminal approach is a safe route and the most direct path to excise third ventricular colloid cyst, without dependence on hydrocephalus...

..The combination of inadequate technology and incomplete nomenclature systems created challenges for early neurosurgeons, and contributed to the dismal prognosis for brain tumors, particularly within the pediatric population...

..In this report the authors highlight possible pitfalls in the diagnosis of some lesions of the third ventricle, and the possible advantages of using a combined endoscopic and microsurgical technique when approaching such lesions...

..A brief review of literature is also presented with this case illustration...

..The Section of Neuroendoscopy of the Italian Neurosurgical Society invited some of its members to review their own experience, gathering a sufficient number of cases for a wide analysis...

..Therefore, a subtle preoperative radiological diagnosis is warranted and surgery should be performed by experienced hands to avoid neurological deterioration...

..The study stressed the value of the widen and careful neurootological examination in such cases...

..Importantly, intra-/periventricular region appears to be the most common extracortical location of cerebral DNT with a 100% disease-free survival reported in the literature...

..The goal of the present study was to analyze relationships between visual field deficits and the locations of brain tumors compared with optic tracts as visualized by tractography, and compared with the calcarine fissure...

..Subependymomas are rare, slow-growing, ependymal neoplasms that commonly occur in the fourth or lateral ventricles...

..The treatment of choice is surgical. To guarantee good progression, complete ablation is necessary. The clinical progression, radiological aspects, treatment, histopathology, and postoperative progression will be discussed...

..Further imaging and histological studies are needed to improve understanding of the pathophysiological aspects behind it...

..Our simple method of using a cylindrical channel retractor custom made out of 20 cc plastic syringe in OT helps in making minimum possible corticectomy. It gives surgeon minimally traumatic, inexpensive, hands free retractor...

..Although this technique is not exempt of serious complications, morbimortality could be lower than conventional microsurgical approach...

..This unusual observation of the Bruns syndrome in a non-parasitary disease of the CNS adds the syndrome to the differential diagnosis of paroxysmal vertigo...

..A father and son presented ten years apart with a fourth ventricle ependymoma. The history, imaging and pathology are presented and the aetiology of familial ependymoma discussed...

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..Treatment with systemic and intrathecal chemotherapy was ineffective in this patient. We review the literature concerning leptomeningeal dissemination of benign choroid plexus papillomas...

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..However, at the long-term follow-up, children with third ventricle floor tumors had a greater prevalence of being overweight and obese, which was associated with hypothalamic dysfunction...

..Our experience suggests that a synchronous lesion at thalamus and para lateral ventricle seems to be due to subependymal infiltration other than CSF dissemination...

..The authors assess clinical usefulness of neuroendoscopy in the treatment of discussed tumors...

..With the aforementioned interventions, the patient experienced significant clinical and radiographic recovery...

..Most teratomas are midline tumors located predominantly in the sellar and pineal regions. In this study, we report a neonatal intracranial immature teratoma at the lateral ventricle because of its rare location...

..The recognition of DNT with an unusual location in lateral ventricle has therapeutic and prognostic significance since DNT is curable by surgical excision and radiation therapy is of no obvious benefit...

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..This system provides a unique opportunity to investigate an in vivo animal model of childhood medulloblastoma, and to determine the roles of Ptc and Gli in tumorigenesis. ..

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..In summary, high quality fluoroscopy, as provided by the OEC 9800 Digital Mobile Imaging System, is the most important means by which we can continue to refine the primate stroke model. ..

..This would spark further study that could further explore neuroprotective pre-treatment of cerebral ischemia, and thus help neutralize a major source of morbidity and mortality in this disease process. ..