Genomes and Genes
radiation induced neoplasms
Summary: Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation.
Publications238 found, 100 shown here
- Radiation-induced second cancers: the impact of 3D-CRT and IMRTEric J Hall
Center for Radiological Research, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
Int J Radiat Oncol Biol Phys 56:83-8. 2003..75% for patients surviving 10 years. The numbers may be larger for longer survival (or for younger patients), but the ratio should remain the same...
- Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997Dale L Preston
Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
Radiat Res 160:381-407. 2003..Lifetime risk summaries are used to examine uncertainties of the LSS noncancer disease findings...
- Radiation and breast cancer: a review of current evidenceCécile M Ronckers
National Cancer Institute, Division of Cancer Epidemiology and Genetics, NIH, HHS, Bethesda, Maryland, USA
Breast Cancer Res 7:21-32. 2005....
- Radiation carcinogenesisJ B Little
Department of Cancer Cell Biology, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Carcinogenesis 21:397-404. 2000..This 'bystander effect' involves gap junction mediated cell-cell communication, and activation of the p53 damage response pathway. The possible role of these phenomena in radiation carcinogenesis is discussed...
- The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: estimates of radiation-related cancer risksE Cardis
International Agency for Research on Cancer, Lyon, France
Radiat Res 167:396-416. 2007..Further studies will be important to better assess the role of tobacco and other occupational exposures in our risk estimates...
- Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) geneY Yu
Department of Radiation Oncology, The University of Texas Medical Branch, Galveston 77555, USA
Cancer Res 61:1820-4. 2001..The data provide the first evidence that naturally arising allelic variation in a mouse DNA damage response gene may associate with IR response and breast cancer risk...
- Radiation effects on breast cancer risk: a pooled analysis of eight cohortsDale L Preston
Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
Radiat Res 158:220-35. 2002..There is also a suggestion that women with some benign breast conditions may be at elevated risk of radiation-associated breast cancer...
- Primary thyroid cancer after a first tumour in childhood (the Childhood Cancer Survivor Study): a nested case-control studyAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7238, USA
Lancet 365:2014-23. 2005..We aimed to quantify the long-term risk of thyroid cancer after radiotherapy and chemotherapy...
- Cancer risks from medical radiationElaine Ron
Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 7048, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Health Phys 85:47-59. 2003....
- Effect of recent changes in atomic bomb survivor dosimetry on cancer mortality risk estimatesDale L Preston
Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
Radiat Res 162:377-89. 2004..Whether or not one makes allowance for this, there is no statistically significant city difference in the estimated cancer risk...
- A cohort study of thyroid cancer and other thyroid diseases after the chornobyl accident: thyroid cancer in Ukraine detected during first screeningMykola D Tronko
Institute of Endocrinology and Metabolism, Kyiv, Ukraine
J Natl Cancer Inst 98:897-903. 2006..Here we report the results of the first cohort study of thyroid cancer among those exposed as children and adolescents following the Chornobyl accident...
- Cancer mortality risk among workers at the Mayak nuclear complexN S Shilnikova
Southern Urals Biophysics Institute, Ozyorsk, Russia
Radiat Res 159:787-98. 2003..As dose estimates for the Mayak workers are improved, it should be possible to obtain more precise estimates of solid cancer and leukemia risks from protracted external radiation exposure in this cohort...
- The role of UV induced lesions in skin carcinogenesis: an overview of oncogene and tumor suppressor gene modifications in xeroderma pigmentosum skin tumorsLeela Daya-Grosjean
Laboratory of Genetic Instability and Cancer, UPR2169 CNRS, IFR 54, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
Mutat Res 571:43-56. 2005....
- Personal sun exposure and risk of non Hodgkin lymphoma: a pooled analysis from the Interlymph ConsortiumAnne Kricker
School of Public Health, University of Sydney, Sydney, New South Wales, Australia
Int J Cancer 122:144-54. 2008..Increased recreational sun exposure may protect against NHL...
- Cellular and molecular events leading to the development of skin cancerVladislava O Melnikova
Department of Immunology, The University of Texas M D Anderson Cancer Center, P O Box 301402, Unit 902, Houston, TX 77030, USA
Mutat Res 571:91-106. 2005..In this article, we will review some of the cellular and molecular mechanisms involved in initiation and progression of UV-induced skin cancer...
- Health risks of low dose ionizing radiation in humans: a reviewKedar N Prasad
Center for Vitamins and Cancer Research, School of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Exp Biol Med (Maywood) 229:378-82. 2004..Low doses of ionizing radiation should not be considered insignificant for risks of somatic and heritable mutations and neoplastic and nonneoplastic diseases in humans...
- Low-level exposure to radiofrequency electromagnetic fields: health effects and research needsM H Repacholi
World Health Organization, Geneva, Switzerland
Bioelectromagnetics 19:1-19. 1998..Recent studies that may indicate an increased incidence of cancer in exposed populations should be investigated further...
- Long-term risk of sarcoma following radiation treatment for breast cancerA Taghian
Department of Radiation Therapy, Institut Gustave Roussy, Villejuif, France
Int J Radiat Oncol Biol Phys 21:361-7. 1991....
- Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse modelSimon J Cooper
Department of Radiation Oncology, Arizona Cancer Center, College of Public Health, The University of Arizona, Tucson, AZ, USA
Mol Cancer Res 1:848-54. 2003..These data show that TAM67 can inhibit UVB-induced squamous cell carcinoma formation, suggesting that AP-1 is a good candidate target for the development of new chemoprevention strategies to prevent sunlight-induced skin cancers...
- Latency period of thyroid neoplasia after radiation exposureShoichi Kikuchi
Department of Surgery, UCSF Affiliated Hospitals, 94143 1674, USA
Ann Surg 239:536-43. 2004..To determine the temporal sequence for developing benign and malignant thyroid neoplasms after radiation...
- The effect of intensity-modulated radiotherapy on radiation-induced second malignanciesJeremy D Ruben
William Buckland Radiotherapy Centre, Melbourne, Australia Monash University, Melbourne, Australia
Int J Radiat Oncol Biol Phys 70:1530-6. 2008..To compare intensity-modulated radiotherapy (IMRT) with three-dimensional conformal radiotherapy (3D-CRT) in terms of carcinogenic risk for actual clinical scenarios...
- Iodine deficiency, radiation dose, and the risk of thyroid cancer among children and adolescents in the Bryansk region of Russia following the Chernobyl power station accidentV V Shakhtarin
Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk, Russia
Int J Epidemiol 32:584-91. 2003..No epidemiological studies have been published assessing the modifying effect of iodine deficiency on radiation-induced thyroid cancer following the Chernobyl accident...
- The pathological response to DNA damage does not contribute to p53-mediated tumour suppressionM A Christophorou
Cancer Research Institute and Department of Cellular and Molecular Pharmacology, Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA
Nature 443:214-7. 2006..Such protection is absolutely dependent on p19(ARF)--a tumour suppressor induced not by DNA damage, but by oncogenic disruption of the cell cycle...
- The cancer epidemiology of radiationRichard Wakeford
BNFL, 1100 Daresbury Park, Daresbury, Warrington WA4 4BG, UK
Oncogene 23:6404-28. 2004....
- The sensitivity of children to electromagnetic fieldsLeeka Kheifets
Department of Epidemiology, University of California School of Public Health, Los Angeles, California 90095 1772, USA
Pediatrics 116:e303-13. 2005..It also includes an assessment of the potential susceptibility of children to EMFs and concludes with a recommendation for additional research and the development of precautionary policies in the face of scientific uncertainty...
- Long-term results with resection of radiation-induced soft tissue sarcomasCharles Cha
Surgical Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Ann Surg 239:903-9; discussion 909-10. 2004..Radiation-induced sarcoma is a well recognized if uncommon event. The objective of this study is to determine the prevalence and long-term outcome for patients who develop radiation-induced sarcomas...
- The bystander effect in radiation oncogenesis: II. A quantitative modelD J Brenner
Center for Radiological Research, Columbia University, New York, New York 10032, USA
Radiat Res 155:402-8. 2001..2 Gy. At still lower doses, bystander effects may dominate the overall response, possibly leading to an underestimation of low-dose risks extrapolated from intermediate doses, where direct effects dominate...
- Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiationShigetoshi Sano
Department of Dermatology and Social, Osaka University Graduate School of Medicine, Japan
Cancer Res 65:5720-9. 2005..These data suggest that Stat3 is required for survival and proliferation of keratinocytes following UVB exposure and that Stat3 is tightly regulated as part of a novel protective mechanism against UVB-induced skin cancer...
- Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countriesE Cardis
International Agency for Research on Cancer, Lyons, France
BMJ 331:77. 2005..To provide direct estimates of risk of cancer after protracted low doses of ionising radiation and to strengthen the scientific basis of radiation protection standards for environmental, occupational, and medical diagnostic exposures...
- Tumors of the nervous system and pituitary gland associated with atomic bomb radiation exposureDale L Preston
Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
J Natl Cancer Inst 94:1555-63. 2002..The risk of developing nervous system tumors following exposure to ionizing radiation is not well quantified. We characterized the incidence of nervous system tumors among atomic bomb survivors as a function of radiation dose...
- Cancer risks from diagnostic radiologyE J Hall
Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, USA
Br J Radiol 81:362-78. 2008..A further issue is the increasing use of CT scans as a screening procedure in asymptomatic patients; at this time, the benefit/risk balance for any of the commonly suggested CT screening techniques has yet to be established...
- Cancer risks attributable to low doses of ionizing radiation: assessing what we really knowDavid J Brenner
Center for Radiological Research, Columbia University, 630 West 168th Street, New York, NY 10032, USA
Proc Natl Acad Sci U S A 100:13761-6. 2003..This linearity assumption is not necessarily the most conservative approach, and it is likely that it will result in an underestimate of some radiation-induced cancer risks and an overestimate of others...
- Cancer risk estimates from the combined Japanese A-bomb and Hodgkin cohorts for doses relevant to radiotherapyUwe Schneider
Division of Medical Physics, Department of Radiation Oncology and Nuclear Medicine, The Triemli Hospital Zürich, 8063 Zurich, Switzerland
Radiat Environ Biophys 47:253-63. 2008..The work presented here also provides the first direct evidence that the bending over of the solid cancer excess risk dose response curve for the A-bomb survivors, generally observed above 2 Gy, is due to cell killing effects...
- Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombsS Izumi
Department of Statistics, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima 732 0815 Japan
Br J Cancer 89:1709-13. 2003..97 (95% confidence interval 0.70-1.36). Because of the small number of cases, however, we cannot exclude an increase in cancer incidence at this time...
- The Techa River Cohort: study design and follow-up methodsM M Kossenko
Urals Research Center for Radiation Medicine, Chelyabinsk, Russia
Radiat Res 164:591-601. 2005..The limitations of the study include loss to follow-up due to difficulties in tracing some cohort members and migration and incomplete ascertainment of cause of death...
- Cancer incidence and risk estimation among medical x-ray workers in China, 1950-1995J X Wang
Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjim
Health Phys 82:455-66. 2002..The RR of leukemia was 1.7 and 1.1 for solid cancer. This means a significant cancer risk can be induced by long term fractionated exposure to ionizing radiation when the cumulative dose reaches a certain level...
- Rare variants of ATM and risk for Hodgkin's disease and radiation-associated breast cancersKenneth Offit
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Clin Cancer Res 8:3813-9. 2002..We next sought to determine the frequency of ATM variants in patients with Hodgkin's lymphoma, regardless of coexisting BC, compared with healthy volunteers...
- Arsenic-induced enhancement of ultraviolet radiation carcinogenesis in mouse skin: a dose-response studyFredric J Burns
Department of Environmental Medicine, School of Medicine, New York University, 57 Old Forge Road, Tuxedo, NY 10987, USA
Environ Health Perspect 112:599-603. 2004....
- Using splines to analyse latency in the Colorado Plateau uranium miners cohortM Hauptmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD 20892-7244, USA
J Epidemiol Biostat 6:417-24. 2001..CONCLUSIONS: The proposed spline model is a flexible tool for latency analyses, and extends previously used methods...
- Leukaemias and cancers following iodine-131 administration for thyroid cancerF de Vathaire
National Institute of Health and of Medical Research, Unit 351, Institut Gustave Roussy, Villejuif, France
Br J Cancer 75:734-9. 1997..When digestive tract cancers were excluded, the overall excess relative risk of second cancer per estimated effective sievert received to the whole body was -0.2 (P = 0.6)...
- UV-induced skin damageM Ichihashi
Division of Dermatology, Graduate School of Medicine, Translational Medicine, School of Medicine, Kobe University, Kobe, Japan
Toxicology 189:21-39. 2003..Finally, possible prevention of UV-induced skin cancer by feeding or topical use of antioxidants, such as polyphenols, vitamin C, and vitamin E, is discussed...
- Incidence of cancer among female flight attendants: a meta-analysisOsamu Tokumaru
Department of Hygiene, National Defense Medical College, Tokorozawa, Japan
J Travel Med 13:127-32. 2006..A meta-analysis was conducted to study whether the occupational exposure of female flight attendants (FA) increased their relative risk of cancer incidence...
- Occupational risk factors, ultraviolet radiation, and ocular melanoma: a case-control study in FranceP Guenel
INSERM Unité 88, Hopital National de Saint Maurice, Saint Maurice, France
Cancer Causes Control 12:451-9. 2001..Ultraviolet radiation has been suspected as a possible cause of ocular melanoma. Because this association is controversial, we examine the role of occupational exposure to ultraviolet radiation on the occurrence of this rare cancer...
- Prostatic carcinosarcoma 15 years after combined external beam radiation and brachytherapy for prostatic adenocarcinoma: a case reportT Y Tseng
Division of Urologic Surgery and Duke Prostate Center, Duke University Medical Center, Durham, NC 27704, USA
Prostate Cancer Prostatic Dis 9:195-7. 2006..The increasing use of such combination high-dose radiation therapy may potentially lead to an increased incidence of secondary malignancies such as prostatic carcinosarcoma in the future...
- Incidence of haematopoietic malignancies in US radiologic technologistsM S Linet
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
Occup Environ Med 62:861-7. 2005..There are limited data on risks of haematopoietic malignancies associated with protracted low-to-moderate dose radiation...
- The pathogenesis of mesotheliomaMichele Carbone
Cancer Immunology Program, Cardinal Bernardin Cancer Center, Department of Pathology, Loyola University Chicago, USA
Semin Oncol 29:2-17. 2002..Mesothelioma appears to have a complex etiology in which environmental carcinogens (asbestos and erionite), ionizing radiation, viruses, and genetic factors act alone or in concert to cause malignancy...
- Radiation dose, chemotherapy and risk of lung cancer after breast cancer treatmentCarole Rubino
Unit of Cancer Epidemiology, National Institute of Health and Medical Research U521 INSERM, Institut Gustave Roussy, Villejuif, France
Breast Cancer Res Treat 75:15-24. 2002..10) per gray delivered to the site of lung cancer was evidenced. Our results agree with previous studies in favor of an increased risk of lung cancer after radiation therapy for breast cancer...
- Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of miceM Okumoto
Department of Allied Biological Science, University of Osaka Prefecture, Sakai, Japan
Cancer Res 50:3848-50. 1990....
- Medical radiation, family history of cancer, and benign breast disease in relation to breast cancer risk in young women, USADeirdre A Hill
Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles 90033, USA
Cancer Causes Control 13:711-8. 2002..Some evidence suggests that such risk may be distinctly elevated among women with a family history of breast or ovarian cancer (probably only carriers of specific gene mutations) and women with benign breast disease (BBD)...
- Small-bowel angiosarcoma after pelvic irradiation: a report of two casesP Aitola
Departments of Surgery and Pathology, Tampere University Hospital and Medical School, University of Tampere, P O Box 2000, FIN 33521 Tampere, Finland
Int J Colorectal Dis 14:308-10. 1999..These cases demonstrate poor prognosis in this disease. Although postirradiation angiosarcoma is a rare condition, its possibility should be kept in mind when operating on previously irradiated patients...
- Effect of breast cancer radiotherapy and cigarette smoking on risk of second primary lung cancerElizabeth L Kaufman
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
J Clin Oncol 26:392-8. 2008..Prior studies have found that postmastectomy radiotherapy (PMRT) for breast cancer (BC) increases the risk of lung cancer (LC). We explored the joint effects of cigarette smoking and PMRT on LC risk...
- Impact of ionizing radiation and genetic background on mammary tumorigenesis in p53-deficient miceM G Backlund
Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
Cancer Res 61:6577-82. 2001..Furthermore, it suggests that the risk of development of a particular type of tumor by individuals deficient in p53 after exposure to damaging agents can be influenced by modifier alleles...
- High incidence of meningioma among Hiroshima atomic bomb survivorsT Shintani
Department of Cancer Cytogenetics, Hiroshima University, Japan
J Radiat Res 40:49-57. 1999..There was a significant correlation between the incidence and the dose of radiation to the brain. The present findings strongly suggest that meningioma is one of the tumors induced by atomic bombing in Hiroshima...
- Radiation-induced thyroid carcinogenesis as a function of time and dietary iodine supply: an in vivo model of tumorigenesis in the ratCarsten Boltze
Department of Pathology, Otto von Guericke University, D 39120 Magdeburg, Germany
Endocrinology 143:2584-92. 2002..This model may help to define genetic alterations long before histological changes are detectable...
- Uranium mining in Germany: incidence of occupational diseases 1946-1999Christa Schröder
Hauptverband der gewerblichen Berufsgenossenschaften HVBG, 53754 Sankt Augustin, Germany
Int Arch Occup Environ Health 75:235-42. 2002..The present study gives an overview of the occurrence of occupational diseases during the mining period as well as after uranium mining was stopped in 1990...
- Case-control study on childhood cancer in the vicinity of nuclear power plants in Germany 1980-2003Claudia Spix
German Childhood Cancer Registry, Institute for Medical Biostatistics, Epidemiology and Informatics, University Mainz, 55101 Mainz, Germany
Eur J Cancer 44:275-84. 2008..They contrast with the lack of an effect observed or expected from other studies due to low doses from routine nuclear power plant operation...
- Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in miceC Barlow
Nat Genet 21:359-60. 1999
- Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation WorkersC R Muirhead
Health Protection Agency, Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxon OX11 0RQ, UK
Br J Cancer 100:206-12. 2009..The cancer risk estimates are consistent with values used to set radiation protection standards...
- Breast cancer following radiotherapy and chemotherapy among young women with Hodgkin diseaseLois B Travis
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
JAMA 290:465-75. 2003..Quantitative associations between radiotherapy dose delivered to the breast and administered chemotherapy have not been reported to date in large series, nor has the influence of ovarian exposures on subsequent risk...
- Cancer consequences of the Chernobyl accident: 20 years onElisabeth Cardis
International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
J Radiol Prot 26:127-40. 2006....
- Dose to the contralateral breast from radiotherapy and risk of second primary breast cancer in the WECARE studyMarilyn Stovall
Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 72:1021-30. 2008..To quantify the risk of second primary breast cancer in the contralateral breast (CB) after radiotherapy (RT) for first breast cancer...
- Late cancer and noncancer risks among Chernobyl emergency workers of RussiaVictor K Ivanov
Medical Radiological Research Center of Russian Academy of Medical Sciences, 4 Korolev Street, Obninsk, Kaluga Region, 249036, Russia
Health Phys 93:470-9. 2007..64; 3.69). Different but overlapping cohorts of Russian emergency workers were used for these estimations. No adjustments were made for recognized risk factors for cerebrovascular diseases. All results should be considered as preliminary...
- Cancer risks among radiologists and radiologic technologists: review of epidemiologic studiesShinji Yoshinaga
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Radiology 233:313-21. 2004....
- Risk of thyroid cancer after exposure to 131I in childhoodElisabeth Cardis
International Agency for Research on Cancer, Lyon, France
J Natl Cancer Inst 97:724-32. 2005....
- Radiation-induced malignancies following radiotherapy for breast cancerR Roychoudhuri
Thames Cancer Registry, Division of Cancer Studies, Guy s, King s and St Thomas School of Medicine, 1st Floor, Capital House, 42 Weston Street, London SE1 3QD, UK
Br J Cancer 91:868-72. 2004..99, 95% CI 1.13-9.33), for second breast cancer at 5-10 years (RR 1.34, 95% CI 1.10-1.63) and 15+ years (RR 1.26, 95% CI 1.00-1.59) and oesophageal cancer at 15+ years (RR 2.19, 95% CI 1.10-4.62)...
- Radiation and the microenvironment - tumorigenesis and therapyMary Helen Barcellos-Hoff
Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA
Nat Rev Cancer 5:867-75. 2005..These alterations in the microenvironment can contribute to carcinogenesis and alter the tissue response to anticancer therapy. Examples of these responses and their implications are discussed with a view to therapeutic intervention...
- Bone cancer risk in mice exposed to 224Ra: protraction effects from promotionW F Heidenreich
GSF Institute for Radiation Protection, 85764 Neuherberg, Germany
Radiat Environ Biophys 44:61-7. 2005..13 mGy/day are found to double the baseline initiation rate. At rates above 100 mGy/day, the initiation rate decreases. The clonal expansion rate is doubled at 8 mGy/day, and it levels out at rates beyond 100 mGy/day...
- Biological effects from electromagnetic field exposure and public exposure standardsLennart Hardell
Department of Oncology, University Hospital, SE 701 85 Orebro, Sweden
Biomed Pharmacother 62:104-9. 2008..Other health impacts associated with exposure to electromagnetic fields not summarized here may be found in the BioInitiative Report at www.bioinitiative.org...
- Chemopreventive effects of alpha-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless miceChandradhar Dwivedi
Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA
Carcinogenesis 27:1917-22. 2006..Together, for the first time, our findings suggest that alpha-santalol could be a potential chemopreventive agent against UVB-induced skin tumor development and, therefore, warrants further investigations...
- Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studiesS Darby
Clinical Trials Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Oxford OX2 6HE
BMJ 330:223. 2005..To determine the risk of lung cancer associated with exposure at home to the radioactive disintegration products of naturally occurring radon gas...
- Biomarkers of induced electromagnetic field and cancerJ Behari
School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110067, India
Indian J Exp Biol 45:77-85. 2007..Finally a mechanism comprising the extremely low frequency and radio frequency (RF)/microwave (MW) modulated field is compared...
- Hepatocellular carcinoma among atomic bomb survivors: significant interaction of radiation with hepatitis C virus infectionsGerald B Sharp
Department of Epidemiology, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima, 732 0815 Japan
Int J Cancer 103:531-7. 2003....
- Increased risk of squamous cell esophageal cancer after adjuvant radiation therapy for primary breast cancerLydia B Zablotska
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Epidemiol 161:330-7. 2005..This finding appears to be a function of the portals used for postmastectomy radiation therapy, which do not expose the lowest third of the esophagus, where adenocarcinomas commonly arise...
- Screening mammography for young women treated with supradiaphragmatic radiation for Hodgkin's lymphomaL Lee
Division of Medical Oncology and Hematology, Massachusetts General Hospital Cancer Center, USA
Ann Oncol 19:62-7. 2008..Female survivors of Hodgkin's lymphoma (HL) treated with supradiaphragmatic radiation therapy (SRT) are at increased risk of breast cancer (BC), but there is little data on the optimal screening strategy...
- Mammographic breast cancer screening for women previously treated with high breast doses for diseases such as Hodgkin'sK Faulkner
Quality Assurance Reference Centre, Wallsend, Tyne and Wear NE28 9ND, UK
Radiat Prot Dosimetry 117:330-3. 2005..In the United Kingdom, the Department of Health has recommended annual screening for these women...
- Incidence of bone and soft tissue sarcoma after radiotherapy: a cohort study of 295,712 Finnish cancer patientsAnna Virtanen
School of Public Health, University of Tampere, Tampere, Finland
Int J Cancer 118:1017-21. 2006..In conclusion, radiotherapy appears to be associated with an increased risk of developing sarcoma especially among younger patients. Further investigation is needed to clarify the dose-response of the preceding ionizing radiation...
- Understanding estimation of time and age effect-modification of radiation-induced cancer risks among atomic-bomb survivorsFrederic Lagarde
Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima 732 0815, Japan
Health Phys 91:608-18. 2006..Also, due to collinearity between these effect-modifier variables, all three models with two of the effect-modifiers necessarily show equivalent fits...
- A prospective study of thyroid nodular disease in children and adolescents in western Poland from 1996 to 2000 and the incidence of thyroid carcinoma relative to iodine deficiency and the Chernobyl disasterMarek Niedziela
Department of Pediatric Endocrinology and Diabetes, University of Medical Sciences in Poznan, Poland
Pediatr Blood Cancer 42:84-92. 2004..Chernobyl, located in the neighbouring country of Ukraine, suffered a catastrophic nuclear explosion in April 1986...
- Childhood cancer in the offspring born in 1921-1984 to US radiologic technologistsK J Johnson
Department of Pediatrics, Division of Epidemiology Clinical Research, University of Minnesota, Minneapolis, MN 55455, USA
Br J Cancer 99:545-50. 2008..8 (95% CI 0.7-4.6). In conclusion, we found no convincing evidence of an increased risk of childhood cancer in the offspring of RTs in association with parental occupational radiation exposure...
- Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomasDeric L Wheeler
Department of Human Oncology, Medical School, University of Wisconsin, Madison, Wisconsin 53792, USA
Cancer Res 64:7756-65. 2004..Taken together, the results indicate that PKCepsilon signals UVR-induced TNFalpha release that is linked, at least in part, to the photosensitivity of PKCepsilon transgenic mice...
- Radiation dose, chemotherapy, hormonal treatment and risk of second cancer after breast cancer treatmentC Rubino
, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
Br J Cancer 89:840-6. 2003..This relationship was limited to endometrial cancers and did not modify the relationship with radiation dose. Our results suggest that high radiation doses slightly increase the risk of second malignancies after breast cancer...
- Ionizing radiation and tobacco use increases the risk of a subsequent lung carcinoma in women with breast cancer: case-only designMichaela Prochazka
Department of Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, SE 171 77, Stockholm, Sweden
J Clin Oncol 23:7467-74. 2005..We accessed the lung dose in relation to different radiotherapy techniques, provided the excess relative risk (ERR) estimate for radiation-associated lung cancer, and evaluated the influence of tobacco use...
- Lumpectomy and breast irradiation for breast cancer arising after previous radiotherapy for Hodgkin's disease or lymphomaM Deutsch
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Am J Clin Oncol 24:33-4. 2001..Two women died with distant metastasis but without local recurrence. Breast conservation therapy with radiotherapy is not contraindicated in the woman who has previously been treated with radiotherapy for Hodgkin's disease or lymphoma...
- The possible role of radiofrequency radiation in the development of uveal melanomaA Stang
Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Essen, Germany
Epidemiology 12:7-12. 2001..This is the first study describing an association between radiofrequency radiation exposure and uveal melanoma. Several methodologic limitations prevent our results from providing clear evidence on the hypothesized association...
- Lung tumour risk in radon-exposed rats from different experiments: comparative analysis with biologically based modelsJ C Kaiser
Institute of Radiation Protection, GSF National Research Center for Environment and Health, 85764 Neuherberg, Germany
Radiat Environ Biophys 43:189-201. 2004..In addition, high cumulative exposure exerted lethal effects other than lung cancer on the rats...
- Research on potential radiation risks in areas with nuclear power plants in Japan: leukaemia and malignant lymphoma mortality between 1972 and 1997 in 100 selected municipalitiesYasuhiko Yoshimoto
Research Centre for Radiation Safety, National Institute of Radiological Sciences, Anagawa 4 9 1, Inage ward, Chiba 263 8555, Japan
J Radiol Prot 24:343-68. 2004..Our findings do not support the hypothesis of a leukaemogenic impact of NPPs in Japan...
- Sarcoma after radiation therapy: retrospective multiinstitutional study of 80 histologically confirmed cases. Radiation Therapist and Pathologist Groups of the Fédération Nationale des Centres de Lutte Contre le CancerJ L Lagrange
Radiation Oncology Department, Centre Antoine Lacassagne, 33 Avenue de Valombrose, 06189 Nice 2, France
Radiology 216:197-205. 2000..To evaluate the best strategy for treatment of sarcoma that occurs after radiation therapy...
- Ultrasound-detected thyroid nodule prevalence and radiation dose from falloutC E Land
National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bthesda, MD 20892 7238, USA
Radiat Res 169:373-83. 2008..In terms of excess relative risk per unit dose, our dose-response findings for nodule prevalence are comparable to those from populations exposed to medical X rays and to acute radiation from the Hiroshima and Nagasaki atomic bombings...
- Radiation exposure due to local fallout from Soviet atmospheric nuclear weapons testing in Kazakhstan: solid cancer mortality in the Semipalatinsk historical cohort, 1960-1999Susanne Bauer
Federal Office for Radiation Protection, Institute for Radiation Hygiene, Germany
Radiat Res 164:409-19. 2005..Future epidemiological assessments based on this cohort will benefit from extension of follow-up and ongoing validation of dosimetric data...
- Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisonsJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
Cancer 107:554-62. 2006..Although most are sporadic, some tumors occur in association with prior radiation therapy. The purpose of the current study was to compare clinicopathologic and prognostic features of primary and radiation-associated osteosarcoma...
- Thyroid disease 60 years after Hiroshima and 20 years after ChernobylJohn D Boice
JAMA 295:1060-2. 2006
- Cancer incidence after radiotherapy for skin haemangioma during infancyS Lindberg
Department of Oncology and Radiation Physics, Sahlgrenska University Hospital, , Sweden
Acta Oncol 34:735-40. 1995..4-18.1). The mean dose in the central nervous system was 0.077 Gy and the ERR for brain tumours was 10.9 per Gy (CI 95% 3.7-20.5). This cohort gives a unique opportunity to analyse long-term effects of low-dose irradiation during infancy...
- A unique tumor antigen produced by a single amino acid substitutionP A Monach
Department of Pathology, University of Chicago, Illinois 60637, USA
Immunity 2:45-59. 1995..These results indicate that this unique tumor antigen is derived from a single amino acid substitution in a cellular protein...
- Breast cancer after treatment of Hodgkin's lymphoma: risk factors that really matterMohamed A Alm El-Din
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Int J Radiat Oncol Biol Phys 73:69-74. 2009..To evaluate the risk of breast cancer (BC) and the contributing risk factors in women after supradiaphragmatic irradiation (SDI) for Hodgkin's lymphoma (HL)...
- Age at exposure to ionising radiation and cancer mortality among Hanford workers: follow up through 1994S Wing
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7400, USA
Occup Environ Med 62:465-72. 2005..Studies of workers at the plutonium production factory in Hanford, WA have led to conflicting conclusions about the role of age at exposure as a modifier of associations between ionising radiation and cancer...
- Lumpectomy and partial breast irradiation for early-stage breast cancer following mantle irradiation for Hodgkin's lymphomaMohamed A Alm El-Din
Breast Oncology Unit, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Nat Clin Pract Oncol 5:426-9. 2008....
- Relative risks of radiation-associated cancer: comparison of second cancer in therapeutically irradiated populations with the Japanese atomic bomb survivorsM P Little
National Radiological Protection Board, Chilton, Didcot, Oxon, UK
Radiat Environ Biophys 38:267-83. 1999....
- Effects of alpha-santalol on proapoptotic caspases and p53 expression in UVB irradiated mouse skinBhanu L Arasada
Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA
Anticancer Res 28:129-32. 2008..The objective of the present investigation was to study the effects of alpha-santalol on apoptosis proteins and p53 in UVB-induced skin tumor development in SKH-1 mice to elucidate the mechanism of action...
- Clinical and pathologic features of breast cancers in women treated for Hodgkin's disease: a case-control studyA J Janov
Division of Population Sciences, Dana Farber Institute, Boston, Massachusetts 02115, USA
Breast J 7:46-52. 2001..Cases appeared to be at increased risk of developing additional cancers, but we cannot exclude surveillance as a possible contributing factor...
- Radiation-induced cell inactivation can increase the cancer riskW F Heidenreich
GSF Institute for Radiation Protection, Neuherberg, Germany
Radiat Res 155:870-2. 2001..A major part of the radon-induced lung cancers in the Colorado miners can be explained by a moderate increase in the replacement probability...
- Modest increased sensitivity to radiation oncogenesis in ATM heterozygous versus wild-type mammalian cellsL B Smilenov
Center for Radiological Research, Columbia University, 630 West 168th Street, New York, NY 10032, USA
Cancer Res 61:5710-3. 2001..From these data we suggest that Ataxia Telangiectasia heterozygotes could indeed represent a societally-significant radiosensitive human subpopulation...
- A new ultra-low field in-vivo EPR technology for biomedical applicationsInseob Hahn; Fiscal Year: 2011....
- A new ultra-low field in-vivo EPR technology for biomedical applicationsInseob Hahn; Fiscal Year: 2012....
- Radiation and Genomic Instability in Finite Lifespan Human Mammary EpitheliumAmy Kronenberg; Fiscal Year: 2010....
- Rapid Robust Pediatric MRIShreyas S Vasanawala; Fiscal Year: 2013....
- Automated Radiation Monitoring and Decision Support to Reduce Cumulative ExposureAaron Sodickson; Fiscal Year: 2012..In the long run, with universal adoption of standardized electronic medical records, this work will pave the way for large-scale epidemiologic studies to directly test the underlying cancer risk models of low dose radiation exposure. ..
- IN VIVO INDUCTION AND REPAIR OF GENOMIC INSTABILITYANTONE BROOKS; Fiscal Year: 2000....
- GENOMIC INSTABILITY IN HIGH LET CARCINOGENESISRobert Ullrich; Fiscal Year: 2001....
- High Stability Accelerator for Sub-Cellular MicrobeamDavid Brenner; Fiscal Year: 2003..We have considerably more demand for microbeam time than we can cope with, primarily because of limited physicist manpower. ..
- RADIOLOGICAL RESEARCH ACCELERATOR FACILITY (RARAF)David Brenner; Fiscal Year: 2002..abstract_text> ..
- Cancer Risks Attributable To Radiation from Pediatric CTDavid Brenner; Fiscal Year: 2006..The target audiences will be radiologists, pediatricians, family physicians, and the CT industry. We will use telephone interviews supplemented with survey questions, to aid in web content decisions. ..
- Cancer Risk Assessment: Is There New Science to Apply?Richard Bull; Fiscal Year: 2002..A summary of the meeting will be prepared and this along with any conclusions and recommendations will be submitted to a peer-reviewed journal for publication. ..
- HIGH ENERGY IONS AND GENOMIC INSTABILITYEric Hall; Fiscal Year: 2001....
- Genetic Consequences of Therapies for CancerJohn Boice; Fiscal Year: 2009..abstract_text> ..
- IOWA AND MISSOURI RADON LUNG CANCER STUDIESR Field; Fiscal Year: 2007..The pooling of data between two large-scale epidemiologic studies from a similar geographic area, Iowa and Missouri, will allow us to increase sample size and statistical power. ..
- POPULATION RISK MODEL FOR ALPHA-INDUCED BONE NEOPLASMSRAY LLOYD; Fiscal Year: 2005..7) To develop a general risk model for alpha-induced neoplasms. For this, data in human and experimental studies on radium will be used as a basis for extrapolation to other alpha-emitting nuclides. ..
- GORDON RESEARCH CONFERENCE ON MAMMARY GLAND BIOLOGYMARY BARCELLOS HOFF; Fiscal Year: 2003..abstract_text> ..
- The Risk of Cancer in Fanconi Anemia HeterozygotesMarianne Berwick; Fiscal Year: 2005..Analyses will be undertaken to evaluate the role of Fanconi anemia heterozygosity for cancer. If carriers are found to be at increased risk, this information can be used to target individuals for cancer prevention strategies. ..
- Prospective Investigation for Pulmonary Embolism Dx IIIPaul Stein; Fiscal Year: 2008..abstract_text> ..
- Air Pollution and Adverse Birth OutcomesBeate Ritz; Fiscal Year: 2004..abstract_text> ..
- Updating Chromosome Aberration Simulator (CAS) SoftwareRainer Sachs; Fiscal Year: 2006..An interdisciplinary team has been assembled for this project. The grant would ensure that a computer resource important to the radiation cytogenetics community is kept fully current and readily available. ..
- Regulation of BCL-2 and TumorigenicityMarc Mendonca; Fiscal Year: 2006..abstract_text> ..
- Imaging & Localizing Device Using the Barkhausen EffectJohn Dicello; Fiscal Year: 2003..Existing reconstruction techniques will be adapted to provide absolute spatial information. With fusion, images can be combined with CT, MRI, or PET for anatomical and physiological information. ..
- Repair & Prevention of DNA Damage & Breast Cancer RiskRoy Shore; Fiscal Year: 2005..The polymorphisms either have not been studied previously in relation to breast cancer risk, or their contribution to risk is uncertain because of limitations in previous studies. ..
- CYTOGENETIC MODELS FOR ASSESSING LOW DOSE RADIATION RISKRainer Sachs; Fiscal Year: 2001..By studying molecular, mechanisms relevant to low doses and low dose-rates quantitatively the project will help firm-up risk estimates and make them more credible. ..
- 16th World Congress of EpidemiologyDavid Savitz; Fiscal Year: 2002..Symposia and scientific sessions for poster and oral presentations will provide a dynamic forum for discussion in all of these areas. ..
- RADIATION INDUCED THYROID CANCERARTHUR SCHNEIDER; Fiscal Year: 2002..These studies will focus on rearrangements of the ret protooncogene in thyroid neoplasms and the NF2 tumor suppressor gene in neural tumors. ..
- Registry Study of Parkinsons Disease in DenmarkBeate R Ritz; Fiscal Year: 2010..The proposed research cannot be performed in the US due to a lack of population PD registries that would provide access to such a large number of cases and valid methods for control recruitment from the general population. ..
- Ergonomic Interventions for Garment WorkBeate Ritz; Fiscal Year: 2004..This study will provide employers, employees and public agencies with evidence of the effectiveness of ergonomic interventions in order to guide health and safety policy. ..
- Solar Exposure and Melanoma SurvivalMarianne Berwick; Fiscal Year: 2009..2. Determine whether functional polymorphic variants in the vitamin D receptor affect survival from melanoma. 3. Investigate the interaction of lifetime solar exposure and polymorphisms in VDR and its effect on survival. ..
- PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-IIPaul Stein; Fiscal Year: 2003..4) The team of investigators is strong, and has collaborated previously in successful research in PE. ..
- CARP, A Novel Cell Death RegulatorWafik El Deiry; Fiscal Year: 2006..Specific Aim 3: To study the functional consequences of perturbing or blocking CARP expression. These studies should provide novel insights into the cellular control of the extrinsic pathway of apoptosis. ..
- PGE2 Receptor Function in SkinAlice P Pentland; Fiscal Year: 2010..at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description, ..
- TGFb Regulation of ER Receptor Positive Mammary CellsMARY BARCELLOS HOFF; Fiscal Year: 2006..3: To determine whether TGF-beta regulation of the ER+ subpopulation contributes to progression and/or features of preneoplastic lesions. ..
- Magnetic Sorter Channels for Stem CellsPaul Todd; Fiscal Year: 2006..abstract_text> ..
- Meningioma: Risk Factors and Quality of LifeMelissa L Bondy; Fiscal Year: 2010..This study represents the first concentrated effort to examine environmental and genetic risk factors for meningiomas. ..
- CARCINOGENIC INTERACTIONS OF RADIATION AND CHEMICALSRobert Ullrich; Fiscal Year: 2007..abstract_text> ..
- Microenvironmental Control of the Radiation ResponseAdam Dicker; Fiscal Year: 2007..The use of these tools in organotypic reconstructs promises to provide novel information about cell survival signaling in an 'in vivo' context with clear implications for therapeutic intervention. ..
- COMMUNITY HEALTH & ENVIRONMENTAL REAWAKENINGSteven Wing; Fiscal Year: 2007....
- Prediction of Second Cancer Risks for Children Treated with Proton - vs. - PhotonWayne D Newhauser; Fiscal Year: 2010..In the future, we expect that the lower-risk treatments will result in fewer second cancers and this will translate into longer, higher-quality lives for survivors of childhood cancer (presently 270,000 persons in the United States). ..
- Bayesian Models for Gene Expression with Microarray DataBani Mallick; Fiscal Year: 2007....
- Gene Therapy Reduction of Radiotherapy EsophagitisJoel S Greenberger; Fiscal Year: 2010..These studies should elucidate the molecular mechanism of induction of damage to engrafting marrow origin, epithelial stem cells by the irradiated esophageal microenvironment and identify new targets for therapeutic intervention. ..
- Data Coordinating Center for Sleep Heart HealthMarie Diener West; Fiscal Year: 2007..abstract_text> ..
- Tobacco Prevention/Cessation Education: Medical StudentsAlan Geller; Fiscal Year: 2006..modules, plans for integration, and faculty training Aim3 - Conduct trial implementation Aim4 - Conduct a comprehensive, formative, process and impact evaluation Aim5 - Disseminate teaching guides to other medical schools ..
- Unique BRCA1 transcriptional response leading to repairWafik El Deiry; Fiscal Year: 2006..Our studies will increase our understanding of the mechanism of action of BRCA1 and may provide novel strategies for therapeutic design, for example by targeting DDB2. ..
- CLINICAL PET AND LABORATORY STUDIES OF ADRENERGIC TUMORSBarry Shulkin; Fiscal Year: 2002....
- Vaccine therapy of congenital adrenal HyperplasiaScott Rivkees; Fiscal Year: 2003..We also anticipate being able to extend this novel approach to the treatment of other receptor-mediated endocrine disorders, such as hyperthyroidism. ..
- ACTIVE LIFE EXPECTANCY IN OLD AND OLDEST OLD POPULATIONSKenneth Manton; Fiscal Year: 2002..Using the detailed measures of disability made in each NLTCS wave, the project will examine more refined changes in specific types and intensity of disability and differences over age, race, gender, and education. ..
- MECHANISMS OF INDUCTION OF SKIN CANCERS BY UV LIGHTHONNAVARA ANANTHASWAMY; Fiscal Year: 2004..In addition, the results may suggest that similar mechanisms be involved in skin cancer development in humans. ..
- Genetic Mutations in Gliomatosis CerebriMarcus Ware; Fiscal Year: 2004..We shall use this data to determine if there are specific patterns of chromosome aberrations that are characteristic of GC. Our final goal is to compare copy-number aberrations seen in GC to those seen in other non-GC astrocytic tumors. ..
- Prevention of Skin Cancer by Scutellaria BaicalensisHuachen Wei; Fiscal Year: 2004..abstract_text> ..
- KILLER/DR5 AND TUMORIGENESISWafik El Deiry; Fiscal Year: 2001..These experiments could lead to novel strategies for anti-cancer therapy. ..
- RASSF1 Tumor Suppressor GeneGERD PFEIFER; Fiscal Year: 2005..The effect of RASSF1 expression on RAS signaling pathways will be studied. We will examine if RASSF1A, alone or in combination with activated RAS, induces cell death (apoptosis). ..
- MOLECULAR EPIDEMIOLOGY OF GLIOMASMelissa Bondy; Fiscal Year: 2004..no abstract available ..
- ACTIVATING MULTIETHNIC YOUTH FOR SMOKING PREVENTIONKaren Glanz; Fiscal Year: 2002..abstract_text> ..
- Effects of TPA on Leukemia and Solid TumorsAllan Conney; Fiscal Year: 2006..Blood levels of TPA that are associated with inhibition of tumor growth will be determined. The effect of inhibitors of tumor growth on proliferation and apoptosis in the tumors will be determined. ..
- CB1 Receptor Action on the Developing HippocampusScott Rivkees; Fiscal Year: 2005..We anticipate that these studies will result in new insights into the potential effects of cannabinoid action on the developing brain. ..
- Eugene P. Cronkite SymposiumNicholas Dainiak; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- BYSTANDER EFFECTS AND X RAY INDUCED GENOMIC INSTABILITYWilliam Morgan; Fiscal Year: 2004..Identifying the BSEF would enhance our understanding of how radiation exerts its deleterious effects and could directly impact risk estimation for radiation exposure. ..
- c-erbB-2 and Risk of Contralateral Breast CancerChristopher Li; Fiscal Year: 2007..unreadable] [unreadable]..
- Cardiovascular Risk 50 Years After Thymic IrradiationMichael Adams; Fiscal Year: 2007..This group of individuals, if shown to be at high risk, constitutes a potentially huge number of persons who may benefit from additional preventive measures. ..
- Targeted Alpha-Particle Emitter Therapy of MetastasesGeorge Sgouros; Fiscal Year: 2009..The work described in this application is intended to develop and evaluate such an approach. ..
- Mechanisms of Radiation-Induced Genomic IstabilityWilliam Morgan; Fiscal Year: 2005....
- Protein Biomarkers of Cancer Risk in Older PersonsChristopher Li; Fiscal Year: 2008..unreadable] [unreadable]..
- Prevention of skin cancer by green tea polyphenolsSantosh Katiyar; Fiscal Year: 2009..Importantly, worldwide interest in green tea as a cancer chemopreventive agent for humans is increasing because it is non-toxic, affordable, popular beverage and is effective in a wide range of organs. ..
- CANCER EPIDEMIOLOGYLeslie Robison; Fiscal Year: 2002..Extensive data bases are available to trainees as well as current studies. Finally, the University has recently established a new Cancer Center with a strong program in cancer prevention and etiology. ..
- VITAMIN D AND THE DIFFERENTIATION OF KERATINOCYTESDaniel Bikle; Fiscal Year: 2003..abstract_text> ..
- REGULATION OF INTESTINAL CALCIUM TRANSPORT BY VITAMIN DDaniel Bikle; Fiscal Year: 2001..These manipulations will all be tested for their ability to block 1,25D-stimulated calcium transport. ..
- PROJECT ALLIFE-EXERCISE AND LEUKEMIA SURVIVORSKevin Oeffinger; Fiscal Year: 2006..This study will represent the first clinical trial aimed at increasing physical activity in leukemia survivors and will advance our understanding of this vulnerable population. ..
- Role of HPV16 E7/E2F6 interaction in viral oncogenesisMargaret McLaughlin Drubin; Fiscal Year: 2006..These studies will further the understanding of how viral proteins interact with cellular factors to induce cancer. [unreadable] [unreadable] [unreadable] [unreadable]..
- Proanthocyanidins: Novel Skin Cancer Preventive AgentSantosh Katiyar; Fiscal Year: 2006..Prevention of skin cancer risk will result to protect and prolong the human health and lives. ..
- Prevention of Photocarcinogenesis by antioxidantSantosh Katiyar; Fiscal Year: 2003..abstract_text> ..
- Trace elements among Iowa pesticide applicatorsLeslie Dennis; Fiscal Year: 2004..abstract_text> ..