odontogenic tumors

Summary

Summary: Neoplasms produced from tooth-forming tissues.

Top Publications

  1. ncbi Relative frequency of central odontogenic tumors: a study of 1,088 cases from Northern California and comparison to studies from other parts of the world
    Amos Buchner
    Department of Oral Pathology and Oral Medicine, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel
    J Oral Maxillofac Surg 64:1343-52. 2006
  2. doi The odontogenic keratocyst: a cyst, or a cystic neoplasm?
    T J Li
    Department of Oral Pathology, Peking University School and Hospital of Stomatology, 22 South Zhongguancun Avenue, Haidian District, Beijing 100081, PR China
    J Dent Res 90:133-42. 2011
  3. doi Recurrence rate of keratocystic odontogenic tumor after conservative surgical treatment without adjunctive therapies - A 35-year single institution experience
    Judith A E M Zecha
    VU University Medical Center VUmc Academic Center for Dentistry Amsterdam ACTA, Department of Oral and Maxillofacial Surgery Pathology, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    Oral Oncol 46:740-2. 2010
  4. ncbi Immunohistochemical detection of amelogenin and cytokeratin 19 in epithelial odontogenic tumors
    H Kumamoto
    Department of Oral Pathology, Tohoku University School of Dentistry, Sendai, Japan
    Oral Dis 7:171-6. 2001
  5. ncbi New findings and controversies in odontogenic tumors
    Adalberto Mosqueda-Taylor
    Health Care Department, Universidad Autonoma Metropolitana Xochimilco, Mexico, D F
    Med Oral Patol Oral Cir Bucal 13:E555-8. 2008
  6. ncbi Cytokeratins in epithelia of odontogenic neoplasms
    M M Crivelini
    Department of Oral Pathology, School of Dentistry, State University, Aracatuba, Sao Paulo, Brazil
    Oral Dis 9:1-6. 2003
  7. ncbi Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital
    Akinola Ladipo Ladeinde
    Department of Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Lagos, Nigeria
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:191-5. 2005
  8. ncbi Keratocystic odontogenic tumor: a retrospective study of 183 cases
    Patricia González-Alva
    Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Japan
    J Oral Sci 50:205-12. 2008
  9. doi Expression of Ki-67, p53 and p63 proteins in keratocyst odontogenic tumours: an immunohistochemical study
    Clarissa Araújo Silva Gurgel
    Laboratory of Histopathology of the Gonçalo Moniz Research Center Oswaldo Cruz Foundation, Salvador, Bahia, Brazil
    J Mol Histol 39:311-6. 2008
  10. doi Reclassification of odontogenic keratocyst as tumour. Impact on the odontogenic tumours prevalence
    L A Gaitán-Cepeda
    Oral Pathology Laboratory, Dental School, National Autonomous University of Mexico, Mexico City, Mexico
    Oral Dis 16:185-7. 2010

Detail Information

Publications229 found, 100 shown here

  1. ncbi Relative frequency of central odontogenic tumors: a study of 1,088 cases from Northern California and comparison to studies from other parts of the world
    Amos Buchner
    Department of Oral Pathology and Oral Medicine, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel
    J Oral Maxillofac Surg 64:1343-52. 2006
    To determine the relative frequency of central odontogenic tumors in relation to all biopsy specimens and to one another in an oral pathology biopsy service and to compare the data with previous studies from different parts of the world.
  2. doi The odontogenic keratocyst: a cyst, or a cystic neoplasm?
    T J Li
    Department of Oral Pathology, Peking University School and Hospital of Stomatology, 22 South Zhongguancun Avenue, Haidian District, Beijing 100081, PR China
    J Dent Res 90:133-42. 2011
    ..Since some advocate a more conservative treatment for OKCs, notably marsupialization and decompression, future treatment strategies may focus on molecular approaches and eventually reduce or eliminate the need for aggressive surgeries...
  3. doi Recurrence rate of keratocystic odontogenic tumor after conservative surgical treatment without adjunctive therapies - A 35-year single institution experience
    Judith A E M Zecha
    VU University Medical Center VUmc Academic Center for Dentistry Amsterdam ACTA, Department of Oral and Maxillofacial Surgery Pathology, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    Oral Oncol 46:740-2. 2010
    ....
  4. ncbi Immunohistochemical detection of amelogenin and cytokeratin 19 in epithelial odontogenic tumors
    H Kumamoto
    Department of Oral Pathology, Tohoku University School of Dentistry, Sendai, Japan
    Oral Dis 7:171-6. 2001
    Epithelial odontogenic tumors exhibit considerable histological variation and are classified into several benign and malignant entities...
  5. ncbi New findings and controversies in odontogenic tumors
    Adalberto Mosqueda-Taylor
    Health Care Department, Universidad Autonoma Metropolitana Xochimilco, Mexico, D F
    Med Oral Patol Oral Cir Bucal 13:E555-8. 2008
    b>Odontogenic tumors comprise a heterogeneous group of lesions that ranges from hamartomas to benign and malignant neoplasms of variable aggressiveness...
  6. ncbi Cytokeratins in epithelia of odontogenic neoplasms
    M M Crivelini
    Department of Oral Pathology, School of Dentistry, State University, Aracatuba, Sao Paulo, Brazil
    Oral Dis 9:1-6. 2003
    ..Cytokeratins 13 and 19 labelled squamous differentiation or epithelial cells near the surface epithelium, and CK7 had variable expression...
  7. ncbi Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital
    Akinola Ladipo Ladeinde
    Department of Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Lagos, Nigeria
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:191-5. 2005
    This study sought to determine the relative frequency of odontogenic tumors in a Nigerian population and to compare these data with previous reports.
  8. ncbi Keratocystic odontogenic tumor: a retrospective study of 183 cases
    Patricia González-Alva
    Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Japan
    J Oral Sci 50:205-12. 2008
    ..Pathological examination of KCOT is important to avoid misdiagnosis and provide appropriate treatment and follow-up...
  9. doi Expression of Ki-67, p53 and p63 proteins in keratocyst odontogenic tumours: an immunohistochemical study
    Clarissa Araújo Silva Gurgel
    Laboratory of Histopathology of the Gonçalo Moniz Research Center Oswaldo Cruz Foundation, Salvador, Bahia, Brazil
    J Mol Histol 39:311-6. 2008
    ..To investigate the immunohistochemical expression of Ki-67, p53 and p63 in Keratocyst Odontogenic Tumours (KOTs) in order to contribute to the biological profile of this tumor...
  10. doi Reclassification of odontogenic keratocyst as tumour. Impact on the odontogenic tumours prevalence
    L A Gaitán-Cepeda
    Oral Pathology Laboratory, Dental School, National Autonomous University of Mexico, Mexico City, Mexico
    Oral Dis 16:185-7. 2010
    ..The aim of this study was to establish the impact of the redefinition and reclassification of odontogenic keratocyst (OKC) as a tumour on the prevalence of odontogenic tumours (OT)...
  11. ncbi Cell proliferation and apoptosis in keratocystic odontogenic tumors
    Gláucia Cardoso Paixão Mateus
    Oral Pathology Laboratory, School of Dentistry, Pontificia Universidade Catolica de Minas Gerais, Belo Horizonte, MG, Brazil
    Med Oral Patol Oral Cir Bucal 13:E697-702. 2008
    Keratocystic odontogenic tumors (KOTs), also known as odontogenic keratocysts, were recently classified as a benign neoplasia due to the aggressive clinical behavior...
  12. ncbi Clear-cell variant of calcifying epithelial odontogenic tumor: clinical and radiographic characteristics
    Yakir Anavi
    Department of Oral and Maxillofacial Surgery, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:332-9. 2003
    ..Clear cells have been reported in approximately 8% of cases of calcifying epithelial odontogenic tumor (CEOT). The purpose of this study was to describe the clinical and radiographic features of clear-cell CEOT (CCEOT)...
  13. doi miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors
    Marina Gonçalves Diniz
    Department of Oral Surgery and Pathology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Cell Oncol (Dordr) 35:285-91. 2012
    ..The purpose of this study was to investigate whether the transcription of miR-15a and miR-16-1 is altered in KCOTs and whether it is associated with BCL2 gene expression in such lesions...
  14. ncbi Extension of Pindborg tumor to the maxillary sinus: a case report
    Nooshin Mohtasham
    Department of Oral and Maxillofacial Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
    J Oral Pathol Med 37:59-61. 2008
    ..epithelial odontogenic tumor is a benign epithelial odontogenic lesion that accounts for less than 1% of all odontogenic tumors. It is most frequently seen in the posterior areas of the mandible...
  15. ncbi Odontogenic tumors in Chile: a study of 362 cases
    Germán Ochsenius
    Oral Pathology Referral Institute, Faculty of Odontology, University of Chile, Santiago, Chile
    J Oral Pathol Med 31:415-20. 2002
    b>Odontogenic tumors are infrequent lesions. Thus, the review of a large number of cases becomes a necessity for both the pathologist and the clinician...
  16. ncbi Hemangiopericytoma associated with multiple keratocystic odontogenic tumors in an adolescent patient: a case report
    Rajdeep Brar
    Department of Oral Medicine and Radiology, M M College of Dental Sciences and Research, Ambala, India
    J Oral Sci 50:233-7. 2008
    ..Here we present a case of hemangiopericytoma of the submandibular region with keratocystic odontogenic tumors in an adolescent patient.
  17. ncbi Nucleolar organizer regions in selected odontogenic lesions
    Behnam Eslami
    Shahid Beheshti University of Medical Sciences and Dental Research Center of Iran, Tehran, Iran
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:187-92. 2003
    ..The present study aimed to assess the usefulness of argyrophilic nucleolar organizer regions (AgNORs) as quantitative criteria in the diagnosis of odontogenic cysts and tumors...
  18. doi Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features
    Rui Amaral Mendes
    Portuguese Catholic University, Viseu, Portugal
    Oral Oncol 46:219-25. 2010
    ..The key element for future management of KCOTs will probably be based on thorough knowledge of the biological basis of this tumor, thereby enabling a more tailored treatment approach...
  19. pmc Keratocystic odontogenic tumor
    Elizabeth A Grasmuck
    Department of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 92134 5000, USA
    Head Neck Pathol 4:94-6. 2010
    ..These characteristics are reviewed in the setting of a typical presentation. The newly acknowledged neoplastic potential and its implications for treatment strategies are also discussed...
  20. ncbi Odontogenic tumors in an Iranian population: a 30-year evaluation
    Nasrollah Saghravanian
    Department of Oral and Maxillofacial Pathology, Faculty of Dentistry and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
    J Oral Sci 52:391-6. 2010
    ..Although the prevalence of odontogenic tumors varies in different geographic sites, there are no reports in English on the relative frequency of ..
  21. doi Keratocystic odontogenic tumor (odontogenic keratocyst): preliminary retrospective review of epidemiologic, clinical, and radiologic features of 261 lesions from University of Turin
    Paolo Boffano
    Division of Maxillofacial Surgery, Head and Neck Department, San Giovanni Battista Hospital, University of Turin, Turin, Italy
    J Oral Maxillofac Surg 68:2994-9. 2010
    To analyze and discuss the demographic, clinical, and surgical aspects of 261 surgically treated keratocystic odontogenic tumors.
  22. pmc Odontogenic epithelium: immunolabeling of Ki-67, EGFR and survivin in pericoronal follicles, dentigerous cysts and keratocystic odontogenic tumors
    Márcia Gaiger de Oliveira
    Graduate Program in Dentistry, Oral Pathology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Head Neck Pathol 5:1-7. 2011
    ..epithelium by immunolabeling of epidermal growth factor receptor (EGFR), Ki-67 and survivin in keratocystic odontogenic tumors (KOT), dentigerous cysts (DC), and pericoronal follicles (PF)...
  23. ncbi Odontogenic tumours in Istanbul: 527 cases
    V Olgac
    Institute of Oncology, Department of Tumor Pathology and Oncological Cytology, Topkapi Capa, Istanbul, Turkey
    Br J Oral Maxillofac Surg 44:386-8. 2006
    ..The posterior mandible was the commonest site (n=184, 35%), followed by the premolar area of the mandible (n=98, 19%), and the anterior maxilla (n=84, 16%)...
  24. pmc Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice
    Yuanrong Gao
    Genetic Laboratory of Development and Diseases, State Key Laboratory of Proteomics, Institute of Biotechnology, Beijing 100071, People s Republic of China
    Mol Cell Biol 29:5941-51. 2009
    Keratocystic odontogenic tumors (KCOTs) are cystic epithelial neoplasias with a high recurrence rate. However, the molecular mechanisms underlying the initiation and progression of KCOTs are still largely unknown...
  25. ncbi Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour
    Jonathan Madras
    Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario
    J Can Dent Assoc 74:165-165h. 2008
    ..Future treatment may involve molecular-based modalities, which may reduce or eliminate the need for aggressive surgical management...
  26. ncbi Odontogenic tumours: a retrospective study of 1642 cases in a Chinese population
    W Jing
    No 14, 3rd Sec, Ren Min Nan Road, Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, PR China
    Int J Oral Maxillofac Surg 36:20-5. 2007
    ..4:1 and 1:4.0, respectively. Ameloblastoma and keratocystic odontogenic tumours, important indications of extensive surgical procedures, are not considered rare in this Chinese population, whereas odontoma is uncommon...
  27. ncbi Odontogenic tumours, a collaborative retrospective study of 75 cases covering more than 25 years from Estonia
    Tiia Tamme
    Department of Maxillofacial Surgery, University of Tartu, Tartu 51014, Estonia
    J Craniomaxillofac Surg 32:161-5. 2004
    ..4 million), and to compare their prevalence with the figures presented in similar reports from other countries...
  28. ncbi Odontogenic tumors in Mexico: a collaborative retrospective study of 349 cases
    A Mosqueda Taylor
    , , Mexico City, Mexico
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 84:672-5. 1997
    Reports about the frequency of odontogenic tumors are scarce, and diagnostic criteria used in the reports are not uniform...
  29. doi Recurrent keratocystic odontogenic tumor in the mandible: a case report and literature review
    Hong Keun Hyun
    Department of Pediatric Dentistry, Dental Research Institute and BK21 Program, School of Dentistry, Seoul National University, Seoul, Korea
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:e7-10. 2009
    ..Here we report a case of a 7-year-old patient with a recurrent keratocystic odontogenic tumor treated by marsupialization for normal development of the involved teeth...
  30. ncbi Locally aggressive central odontogenic fibroma associated to an inflammatory cyst: a clinical, histological and immunohistochemical study
    Iñaki Cercadillo-Ibarguren
    Oral Surgery and Implantology Department, Barcelona University Dental School, Barcelona, Spain
    J Oral Pathol Med 35:513-6. 2006
    ..A cyst with an important inflammatory infiltrate was, moreover, observed...
  31. ncbi Odontogenic tumors: a study of 340 cases in a Brazilian population
    Anacelia Mendes Fernandes
    Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    J Oral Pathol Med 34:583-7. 2005
    The aim of this study was to determinate the relative frequency of odontogenic tumors (OTs) in a Brazilian population and to compare this data with previous reports.
  32. doi Worldwide incidence of odontogenic tumors
    Rafael Linard Avelar
    Department of Oral and Maxillofacial Surgery, Federal University of Ceara, Porto Alegre, Rio Grande do Sul, Brazil
    J Craniofac Surg 22:2118-23. 2011
    The objective of the study was to determine the relative frequency of odontogenic tumors (OTs) in the world population, directing an epidemiologic profile to these lesions.
  33. pmc Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions
    Fumio Ide
    Department of Pathology, Tsurumi University School of Dental Medicine, 2 1 3 Tsurumi, Tsurumi ku, Yokohama, 230 8501, Japan
    Head Neck Pathol 3:18-26. 2009
    Considerable variation in the clinicopathologic presentation of epithelial odontogenic tumors can sometimes be confusing and increase the chance of misdiagnosis. Seven diagnostically challenging jawbone lesions are described...
  34. ncbi Malignant odontogenic tumors. A retrospective and collaborative study of seven cases
    Adalberto Mosqueda Taylor
    Departamento de Atencion a la Salud, Universidad Autonoma Metropolitana Xochimilco, Calzada del Hueso 1100, Col Villa Quietud, Mexico, D F 04960
    Med Oral 8:110-21. 2003
    The frequency, clinico-pathologic features and outcome of malignant odontogenic tumors diagnosed according to the current WHO classification in three pathology services in Mexico City are presented...
  35. ncbi Calcifying epithelial odontogenic (pindborg) tumor of the mandible with clear cell component treated by conservative surgery: report of a case
    Yves Germanier
    Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Berne, Switzerland
    J Oral Maxillofac Surg 63:1377-82. 2005
  36. ncbi A review of 318 odontogenic tumors in Kaduna, Nigeria
    Ezekiel Taiwo Adebayo
    Maxillofacial Unit, Department of Dental Surgery, Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria
    J Oral Maxillofac Surg 63:811-9. 2005
    To analyze 318 odontogenic tumors seen at a tertiary oral care center in Kaduna, Nigeria for comparison with findings in previous Nigerian and world records.
  37. ncbi Imaging characteristics of neoplasms and other lesions of the jawbones: part 1. Odontogenic tumors and tumorlike lesions
    Stavroula J Theodorou
    Department of Radiology, School of Medicine, University of California San Diego Medical Center, San Diego, CA, USA
    Clin Imaging 31:114-9. 2007
    b>Odontogenic tumors of the jawbones arise in the tissues of the odontogenic apparatus...
  38. ncbi Central odontogenic fibroma of mandible: a case report and review of the literature
    John Spencer M Daniels
    Department of Oral and Maxillofacial Surgery, King Fahd Central Hospital, Gizan, Saudi Arabia
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:295-300. 2004
    Central odontogenic fibroma is an extremely rare benign tumor, accounting for less than 0.1% of all odontogenic tumors. The most recent literature review revealed that only 69 cases have so far been reported in the English literature, and ..
  39. ncbi A 4-year prospective study on epidemiology and clinicopathological presentation of odontogenic tumors in Tanzania
    Elison N M Simon
    Department of Oral Surgery and Oral Pathology, School of Dentistry, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:598-602. 2005
    This study, conducted between 1999 and 2003, included all patients with odontogenic tumors referred from all dental clinics and other health facilities in Tanzania to the only 4 referral centers...
  40. ncbi Odontogenic tumors in children and adolescents. A 15-year retrospective study in Argentina
    Marcela Guerrisi
    Catedra de Anatomia Patologica, Facultad de Odontologia, Universidad de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina
    Med Oral Patol Oral Cir Bucal 12:E180-5. 2007
    There are few studies on bucco-maxillary lesions in children and adolescents, and reports on odontogenic tumors (OT) are scanty. Comparison among the available data is difficult due to differences in the criteria used in each study...
  41. ncbi Expression of bone morphogenetic proteins and their associated molecules in ameloblastomas and adenomatoid odontogenic tumors
    H Kumamoto
    Division of Oral Pathology, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Oral Dis 12:163-70. 2006
    ..bone morphogenetic protein (BMPs) and their associated molecules, in oncogenesis and cytodifferentiation of odontogenic tumors, the expression of these regulator molecules were analyzed in epithelial odontogenic tumors as well as in ..
  42. ncbi Odontogenic tumors in Sri Lanka: analysis of 226 cases
    Hiroyuki Okada
    Department of Oral Pathology, Nihon University School of Dentistry at Matsudo, Matsudo, Japan
    J Oral Maxillofac Surg 65:875-82. 2007
    The purpose of this study was to analyze the relative prevalence of odontogenic tumors in Sri Lanka and compare it with prevalences reported for other countries.
  43. ncbi Comparative expression of RANK, RANKL, and OPG in keratocystic odontogenic tumors, ameloblastomas, and dentigerous cysts
    Tarcília Aparecida da Silva
    Department of Oral Surgery and Pathology, Dental School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:333-41. 2008
    ..The aim of this study was to compare the expression of nuclear factor kappaB (RANK), RANK ligand (RANKL), and osteoprotegerin (OPG) in odontogenic epithelial tumors and dentigerous cysts...
  44. doi Odontogenic tumors: a study of 250 cases in an Indian teaching hospital
    G Sriram
    Department of Oral and Maxillofacial Pathology, Nair Hospital Dental College, Mumbai, India
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:e14-21. 2008
    Studies on odontogenic tumors published from many parts of the world show a distinct geographic variation...
  45. doi Co-expression of hepatocyte growth factor and c-met in epithelial odontogenic tumors
    Sopee Poomsawat
    Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
    Acta Histochem 114:400-5. 2012
    ..has been demonstrated in various tumors, however, little is known about the role of HGF/c-met pathway in odontogenic tumors. The aim of this study was to characterize the expression of HGF and c-met in 30 ameloblastomas, 7 unicystic ..
  46. ncbi Odontogenic tumors: a study of 120 cases in an Indian teaching hospital
    A Varkhede
    Government Dental College and Hospital, Mumbai, Maharashtra, India
    Med Oral Patol Oral Cir Bucal 16:e895-9. 2011
    Studies on odontogenic tumors published from many parts of the world show a distinct geographic variation; however, there is little information available in the English-language literature on the relative frequency of odontogenic tumors ..
  47. ncbi Microvessel density in follicular cysts, keratocystic odontogenic tumours and ameloblastomas
    Safora Seifi
    Oral and Maxillofacial Pathology, School of Dentistry, Babol University of Medical Sciences, Babol, Iran
    Asian Pac J Cancer Prev 12:351-6. 2011
    ....
  48. doi Odontogenic tumors: a 5-year retrospective study in a Brazilian population and analysis of 3406 cases reported in the literature
    Rafael Lima Verde Osterne
    Department of Pathology, Fortaleza University School of Medicine, Fortaleza, Ceara, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111:474-81. 2011
    The objective of this study was to analyze the frequency and distribution of odontogenic tumors in Fortaleza, Brazil, and compare the findings with those reported in the literature.
  49. doi A comparative immunohistochemical analysis of COX-2, p53, and Ki-67 expression in keratocystic odontogenic tumors
    Rui Amaral Mendes
    Portuguese Catholic University, Viseu, Portugal
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111:333-9. 2011
    The aim of the present study was to investigate the association between the expression of cyclooxygenase-2 (COX-2) in keratocystic odontogenic tumors (KCOT) and more commonly used markers, such as p53 and Ki-67.
  50. doi Computerized tomography findings and recurrence of keratocystic odontogenic tumor of the mandible and maxillofacial region in a series of 46 patients
    Satu Apajalahti
    Maxillofacial Radiology, Department of Radiology, Helsinki University Central Hospital, Helsinki, Finland
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111:e29-37. 2011
    The aim of this study was to evaluate the computerized tomography (CT) features of keratocystic odontogenic tumors (KCOTs). Another aim was to determine the recurrence rate of KCOTs during a mean follow-up of 4.7 years.
  51. doi Tumor angiogenesis in keratocystic odontogenic tumor assessed by using CD-105 antigen
    Amol Ramchandra Gadbail
    Department of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Sawangi Meghe, Wardha, Maharashtra, India
    J Oral Pathol Med 40:263-9. 2011
    The purpose of this study was to assess and compare angiogenesis with proliferative activity in Keratocystic odontogenic tumors (KCOT) and dentigerous cysts (DC) by using monoclonal mouse anti-human antibody against CD105 (endoglin).
  52. doi Odontogenic tumors in Dakahlia, Egypt: analysis of 82 cases
    Mohamed A Tawfik
    Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:e67-73. 2010
    This study was designed to analyze the frequency and distribution of different types of odontogenic tumors in Dakahlia, Egypt, and to compare them with various reports from other parts of the world.
  53. doi Expression of extracellular matrix proteins in ameloblastomas and adenomatoid odontogenic tumors
    Ana Miryam Costa de Medeiros
    Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande do Norte, Natal, RN, Brazil
    Eur Arch Otorhinolaryngol 267:303-10. 2010
    ..evaluated the expression of fibronectin, tenascin and type I collagen in ameloblastomas and adenomatoid odontogenic tumors (AOTs) aiming to contribute with the comprehension of the differences in the biological behavior of these ..
  54. doi Assessment of computerized tomography density patterns of ameloblastomas and keratocystic odontogenic tumors
    Iêda Crusoé-Rebello
    Department of Oral and Maxillofacial Radiology, School of Dentistry, Federal University of Bahia, Salvador, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:604-8. 2009
    ..patterns of solid ameloblastomas (SA), unicystic ameloblastomas (UA), and sporadic and multiple keratocystic odontogenic tumors (SK and MK, respectively)...
  55. doi Comparison of angiogenesis in keratocystic odontogenic tumours, dentigerous cysts and ameloblastomas
    M Alaeddini
    Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Oral Dis 15:422-7. 2009
    ..The aim of the present study was to evaluate and compare angiogenesis in keratocystic odontogenic tumours, dentigerous cysts (DCs) and ameloblasomas using monoclonal antibody against CD34...
  56. doi Multiple keratocystic odontogenic tumors associated with nevoid basal cell carcinoma syndrome having distinct PTCH1 mutations: a case report
    Ryo Sasaki
    Department of Oral and Maxillofacial Surgery and Institute of Advanced Biomedical Engineering and Science, Tokyo Women s Medical University School of Medicine, Tokyo, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110:e41-6. 2010
    ..Although multiple jaw tumors, such as keratocystic odontogenic tumors (KCOTs), are one of the most frequent complications in NBCCS, the molecular mechanism for how KCOTs develop ..
  57. ncbi Keratocystic odontogenic tumor invading the right maxillary sinus: a case report
    Binali Cakur
    Department of Oral Diagnosis and Radiology, Faculty of Dentistry, Ataturk University, Erzurum, Turkey
    J Oral Sci 50:345-9. 2008
    ..We present the case of a 23-year-old man with extensive KCOT and impacted third molar in the right maxillary sinus. The clinical, radiological, and histological features of this tumor and its surgical management are discussed...
  58. doi Expression of odontogenic ameloblast-associated protein, amelotin, ameloblastin, and amelogenin in odontogenic tumors: immunohistochemical analysis and pathogenetic considerations
    Marcelo Macedo Crivelini
    Department of Pathology and Clinical Propaedeutic, Araçatuba School of Dentistry, Unesp University Estadual Paulista, Aracatuba, SP, Brazil
    J Oral Pathol Med 41:272-80. 2012
    ..for expression of amelogenesis-related proteins represents a powerful molecular approach to characterize odontogenic tumors and investigate their pathogenesis...
  59. ncbi Adenomatoid odontogenic tumour: immunohistochemical demonstration of transferrin, ferritin and alpha-one-antitrypsin
    H Takahashi
    Department of Oral Pathology, Nagasaki University School of Dentistry, Japan
    J Oral Pathol Med 30:237-44. 2001
    ..Furthermore, we indicated that the formation of eosinophilic amorphous material was associated with type I and type II cells...
  60. ncbi Repair of an intrabony defect from an adenomatoid odontogenic tumor
    N M Blumenthal
    Department of Periodontics, College of Dentistry, University of Illinois at Chicago, 60612, USA
    J Periodontol 71:1637-40. 2000
    ..AOT is a rare odontogenic tumor usually associated with unerupted teeth or dentigerous cysts, not periodontal defects. Clinical evaluation 6 months postoperatively revealed restoration of clinical attachment and periodontal health...
  61. ncbi Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors
    T Takata
    Department of Oral Pathology, Faculty of Dentistry, Hiroshima University, Japan
    J Dent Res 79:1608-13. 2000
    ..Since this protease is thought to play important roles in tooth development, the evaluation of enamelysin in odontogenic tumors may aid our understanding of the histogenesis and cell differentiation of such lesions...
  62. ncbi Central granular cell odontogenic tumour: report of the first malignant case and review of the literature
    Adriano Piattelli
    Dental School, University of Chieti, Chieti, Italy
    Oral Oncol 39:78-82. 2003
    ..While the histogenesis of GCOT remains to be clarified, we document the existence of a malignant counterpart of this tumour and propose the name of malignant GCOT or granular cell odontogenic sarcoma for such entity...
  63. ncbi Odontogenic tumors: analysis of 127 cases
    J N Santos
    Department of Pathology, Federal University of Bahia, Brazil
    Pesqui Odontol Bras 15:308-13. 2001
    One hundred and twenty-seven cases of histologically confirmed odontogenic tumors were retrieved from a total of 5,289 oral and maxillary lesions diagnosed at the Division of Oral Pathology, Federal University of Rio Grande do Norte, ..
  64. doi Odontogenic ameloblast-associated protein nature of the amyloid found in calcifying epithelial odontogenic tumors and unerupted tooth follicles
    Charles L Murphy
    Human Immunology and Cancer Program, Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee 37920, USA
    Amyloid 15:89-95. 2008
    We have previously reported that the amyloid found in three patients with calcifying epithelial odontogenic tumors (CEOT) was composed of N-terminal fragments of a putative 153-residue protein specified by a gene designated FLJ20513 now ..
  65. ncbi Expression of basement membrane components in odontogenic tumors
    Sopee Poomsawat
    Department of Oral Pathology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:666-75. 2007
    The objective was to characterize the expression of BMCs (laminins 1 and 5, collagen type IV, and fibronectin) in ameloblastomas, calcifying cystic odontogenic tumors (CCOTs), and adenomatoid odontogenic tumors (AOTs).
  66. pmc Tumours and tumour-like lesions of the lower face at Korle Bu Teaching Hospital, Ghana--an eight year study
    Grace E A Parkins
    Department of Oral and Maxillofacial Surgery, University of Ghana Dental School, College of Health Sciences, Korle Bu, Accra, Ghana
    World J Surg Oncol 5:48. 2007
    ..We report results from a retrospective study spanning eight years on the frequency, clinical presentation, sites and character of lower face tumours seen in the main referral hospital in Ghana...
  67. doi The pattern of odontogenic tumors in a government teaching hospital in the southern Indian state of Tamil Nadu
    Bhawna Gupta
    Department of Oral and Maxillofacial Pathology, Tamil Nadu Government Dental College and Hospital, Chennai, India
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110:e32-9. 2010
    This hospital-based study was designed to provide demographic data on odontogenic tumors from the southern Indian population in the state of Tamil Nadu for comparison with pertinent series from other geographic regions.
  68. ncbi Odontogenic tumours from two centres in Jamaica. A 15-year review
    C O Ogunsalu
    Oral Disease Unit, School of Dentistry, Faculty of Medical Sciences, University of the West Indies, St Augustine, Trinidad and Tobago
    West Indian Med J 52:285-9. 2003
    ..4%, a male). Of all these tumours, only ameloblastomas recurred. Further research is required to explain the high incidence of ameloblastoma, and why it has a predilection for people of low socioeconomic status in Jamaica...
  69. ncbi Primary intraosseous odontogenic carcinoma with osteoid/dentinoid formation
    A Punnya
    Department of Oral Pathology and Microbiology, S D M College of Dental Sciences, Dharwad 580009, Karnataka, India
    J Oral Pathol Med 33:121-4. 2004
    ..The tumour was characterized by sheets of pleomorphic round-to-ovoid cells and marked osteoid/dentinoid formation with foci of globular mineralization...
  70. ncbi Relative frequency of peripheral odontogenic tumors: a study of 45 new cases and comparison with studies from the literature
    Amos Buchner
    Department of Oral Pathology and Oral Medicine, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel
    J Oral Pathol Med 35:385-91. 2006
    Peripheral (extraosseous) odontogenic tumors are rare, and reports in the literature have mainly been single case reports or a small series of cases...
  71. ncbi Central odontogenic fibroma interesting the maxillary sinus. A case report and literature survey
    A Cicconetti
    Department of Oral Surgery Medicine and Pathology, La Sapienza University of Rome, School of Dentistry, Rome, Italy
    Minerva Stomatol 55:229-39. 2006
    ..benign odontogenic tumor deriving from the dental mesenchymal tissue and accounting for less than 5% of all odontogenic tumors. This paper presents an aggressive histologically diagnosed central odontogenic fibroma (COF) in a 17-year-..
  72. ncbi Central odontogenic fibroma--report of a case and review of the literature
    Marie Ramer
    Department of Pathology, Mount Sinai Medical Center, New York, NY 10029, USA
    Periodontal Clin Investig 24:27-30. 2002
    ..With the addition of this case, a total of 68 cases of central odontogenic fibroma have thus far been reported in the English language literature...
  73. ncbi Molecular pathology of odontogenic tumors
    H Kumamoto
    Division of Oral Pathology, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, Sendai, Japan
    J Oral Pathol Med 35:65-74. 2006
    b>Odontogenic tumors are lesions derived from the elements of the tooth-forming apparatus and are found exclusively within the jawbones...
  74. ncbi Primary intraosseous carcinoma associated with impacted third molar of the mandible: review of the literature and report of a new case
    T Shimoyama
    Department of Oral Surgery, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan
    J Oral Sci 43:287-92. 2001
    ..However, delay in establishing the correct diagnosis followed by extraction without awareness of the carcinoma is know to adversely affect the prognosis...
  75. ncbi Case report of intra-osseous fibroma: a study on odontogenic and desmoplastic fibromas with a review of the literature
    Atsushi Ikeshima
    Department of Radiology, Nihon University School of Dentistry at Matsudo, 2 870 1 Sakaecho nishi, Matsudo, Chiba 271 8587, Japan
    J Oral Sci 47:149-57. 2005
    ..Based on the analysis of the reported literature cases, re-evaluation of the patients in our study revealed that case 1 could be classified as desmoplastic fibroma, while cases 2 and 3 were intra-osseous odontogenic fibromas...
  76. ncbi Ameloblastic carcinoma: case report and literature review
    Sylvie Louise Avon
    Faculty of Dentistry, Laval University, Cite Universitaire, Ste Foy, Quebec
    J Can Dent Assoc 69:573-6. 2003
    ..At the moment, there are too few reported cases to make a definite recommendation regarding treatment. Close periodic reassessment of the patient is mandatory...
  77. ncbi A case of multiple AOT-like jawbone lesions in a young patient--a new odontogenic entity?
    A Larsson
    Department of Oral Pathology, Centre for Oral Health Sciences, Sunderby Hospital, Lulea, Sweden
    J Oral Pathol Med 32:55-62. 2003
    ....
  78. doi Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature
    Fumio Ide
    Department of Pathology, Tsurumi University School of Dental Medicine, Yokohama, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:e22-8. 2008
    ..At this time, it remains to be determined whether the biologic behavior of PKCOT is the same as for KCOT. In view of the reported cases, a true extraosseous origin of PAOT and PAF, for the most part, is challenging...
  79. doi Sclerosing odontogenic carcinoma: a previously unreported variant of a locally aggressive odontogenic neoplasm without apparent metastatic potential
    Ioannis G Koutlas
    Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Surg Pathol 32:1613-9. 2008
    ..We propose the name sclerosing odontogenic carcinoma. As current classifications of odontogenic tumors do not include such examples, it is important that pathologists become aware of this entity...
  80. ncbi Odontogenic myxoma: clinico-pathological, immunohistochemical and ultrastructural findings of a multicentric series
    Guillermo Martínez-Mata
    Department of Oral Diagnosis Oral Pathology Section, School of Dentistry of Piracicaba, UNICAMP, Piracicaba, Sao Paulo State, Brazil
    Oral Oncol 44:601-7. 2008
    ..However, further investigations are needed to better understand the participation of these elements in this particular neoplasm...
  81. pmc Msx and dlx homeogene expression in epithelial odontogenic tumors
    Blandine Ruhin-Poncet
    Laboratory of Orofacial Biology and Pathology Centre de Recherche des Cordeliers, INSERM, UMR S 872, Team 5, Pierre and Marie Curie University, Paris, France
    J Histochem Cytochem 57:69-78. 2009
    Epithelial odontogenic tumors are rare jaw pathologies that raise clinical diagnosis and prognosis dilemmas notably between ameloblastomas and clear cell odontogenic carcinomas (CCOCs)...
  82. ncbi Adenomatoid odontogenic tumor: a report of a rare case with recurrence
    Zhou Chuan-Xiang
    Department of Oral Pathology, Peking University School and Hospital of Stomatology, Beijing, China
    J Oral Pathol Med 36:440-3. 2007
    ....
  83. ncbi An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study
    Hans Peter Philipsen
    Edificio El Condor 30, Urb Guadalmina Alta, San Pedro de Alcantara, Spain
    J Oral Pathol Med 36:383-93. 2007
    ..Adenomatoid odontogenic tumour (AOT) is a benign odontogenic jaw lesion. The aim of this study was to update the biological profile of AOT...
  84. ncbi Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population
    Somporn Swasdison
    Department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:210-5. 2008
    ..The aim of this study was to determine the biologic profile of the adenomatoid odontogenic tumor (AOT) in a Thai population...
  85. ncbi Odontogenic myxoma: review of the literature and report of 30 cases from South Africa
    Claudia E E Noffke
    Division of Maxillofacial and Oral Radiology, Oral Health Center, University of Limpopo, Medunsa Campus, Limpopo, South Africa
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:101-9. 2007
    ..The purpose of the study was to analyze the clinical and radiographic features of central odontogenic myxomas (OM) of the jaws diagnosed over 23 years in a black South African patient sample...
  86. doi Odontogenic tumors: a study of 1309 cases in a Chinese population
    Hai Yan Luo
    Department of Oral Pathology, Peking University School and Hospital of Stomatology, 22 South Zhongguancun Avenue, Haidian District, Beijing, PR China
    Oral Oncol 45:706-11. 2009
    To determine the relative frequency of odontogenic tumors (OTs) in a Chinese population, files from the department of oral pathology, Peking University School and Hospital of Stomatology, were systematically reviewed for all OTs during ..
  87. ncbi Ameloblastic fibroma and related lesions: a clinicopathologic study with reference to their nature and interrelationship
    Yan Chen
    Department of Oral Pathology, School and Hospital of Stomatology, Peking University, Beijing, China
    J Oral Pathol Med 34:588-95. 2005
    ..The aim of this study was to elucidate the nature and interrelationship of this group of lesions...
  88. ncbi Squamous odontogenic tumor versus pseudoepitheliomatous hyperplasia
    Lee J Slater
    J Oral Maxillofac Surg 62:1177. 2004
  89. ncbi Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors
    Anu Väänänen
    Department of Diagnostics and Oral Medicine, Institute of Dentistry, University of Oulu, P O Box 5281, 90014 Oulu, Finland
    Matrix Biol 23:153-61. 2004
    ..In odontogenic tumors MMP-20 and collagen XVIII were co-localized in the enamel-like tumor matrix...
  90. ncbi Maxillary unicystic ameloblastoma
    C M Navarro
    Department of Diagnosis and Surgery, Dental School of Araraquara, UNESP, Araraquara, SP, Brazil
    Dentomaxillofac Radiol 33:60-2. 2004
    ....
  91. ncbi Adenoid ameloblastoma with dentinoid: a case report
    Brian L Evans
    Department of Periodontics, Louisiana State University School of Dentistry, New Orleans, LA 70119, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:583-8. 2004
    ..The lesion recurred 3 times over a span of 16 years. A consultative review of all histological findings was done and the tumor was reclassified as an ameloblastoma...
  92. ncbi PTCH1 and SMO gene alterations in keratocystic odontogenic tumors
    L S Sun
    Department of Oral Pathology, Hospital and School of Stomatology, Peking University, Haidian District, Beijing, PR China
    J Dent Res 87:575-9. 2008
    Keratocystic odontogenic tumors (KCOTs, previously known as odontogenic keratocysts) are aggressive jaw lesions that may occur in isolation or in association with nevoid basal cell carcinoma syndrome (NBCCS)...
  93. ncbi Ameloblastic fibroma of the anterior maxilla presenting as a complication of tooth eruption: a case report
    N J McGuinness
    Department of Orthodontics, Merlin Park Hospital, Galway, Ireland
    J Orthod 28:115-8. 2001
    ..Ameloblastic fibroma is a rare mixed odontogenic tumour, which is extremely uncommon in the anterior maxillary region. A case report is presented where failure of eruption of an upper central incisor was the presenting feature...
  94. ncbi Pericoronal squamous odontogenic tumor associated with an impacted mandibular third molar: a case report
    Joseph E Cillo
    Parland Memorial Hospital, The University of Texas Southwestern Medical Center, Dallas 75390 9109, USA
    J Oral Maxillofac Surg 63:413-6. 2005
  95. ncbi Malignant odontogenic tumors: a 22-year experience
    David Goldenberg
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, MD 21287 0910, U S A
    Laryngoscope 114:1770-4. 2004
    Malignant odontogenic tumors are exceedingly rare and arise from odontogenic epithelial residues and odontogenic cysts in the jaw bones. Odontogenic malignancies have various origins...
  96. ncbi Odontogenic tumours in children and adolescents: a study of 78 Nigerian cases
    Ezekiel Taiwo Adebayo
    Maxillofacial Unit, Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria
    J Craniomaxillofac Surg 30:267-72. 2002
    ..To contribute to the records, a 20-year study of odontogenic tumours on the basis of the WHO classification (Kramer et al., 1992) in Nigerian African children and adolescents < or =18 years of age was undertaken...
  97. ncbi Hamartomatous proliferations of odontogenic epithelium within the jaws: a potential histogenetic source of intraosseous epithelial odontogenic tumors
    F Ide
    Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
    J Oral Pathol Med 36:229-35. 2007
    ..remnants of the enamel organ and dental lamina are the only histogenetic option for central epithelial odontogenic tumors. Curiously, incipient tumors or possible precursor conditions of residual odontogenic epithelium have rarely ..
  98. ncbi Ameloblastic carcinoma: an analysis of 14 cases
    James M Hall
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:799-807. 2007
    ..To present the classifications of malignant ameloblastomas, provide histopathologic guidelines for the diagnosis of ameloblastic carcinoma, and discuss treatment and long-term follow-up...
  99. ncbi Immunohistochemical localization of amelogenin in human odontogenic tumors, using a polyclonal antibody against bovine amelogenin
    Y Abiko
    Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido 061 0293, Japan
    Med Electron Microsc 34:185-9. 2001
    In the present study, we investigated the localization of amelogenin in odontogenic tumors, using an anti-amelogenin polyclonal antibody...
  100. ncbi Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws
    Joseph A Regezi
    Oral Pathology and Pathology, Department of Stomatology, University of California, San Francisco, San Francisco, California 94143 0424, USA
    Mod Pathol 15:331-41. 2002
    ..Several odontogenic tumors may provide diagnostic challenges, particularly the cystic ameloblastoma...
  101. ncbi Oral and maxillofacial tumours in north Jordanian children and adolescents: a retrospective analysis over 10 years
    T Al-Khateeb
    Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, PO Box 3030, Jordan
    Int J Oral Maxillofac Surg 32:78-83. 2003
    ..The majority of benign tumours in the young are probably developmental rather than true neoplasms...

Research Grants41

  1. Phenotype and Gene Expression in Odontogenic Tumors
    John Wright; Fiscal Year: 2007
    ..Previous studies show overexpression of and/or mutation of RAS genes in odontogenic tumors and the genesis of tumors in locations where stem cells are localized...
  2. Phenotype and Gene Expression in Odontogenic Tumors
    JOHN T WRIGHT; Fiscal Year: 2010
    ..Previous studies show overexpression of and/or mutation of RAS genes in odontogenic tumors and the genesis of tumors in locations where stem cells are localized...
  3. WNT signals in developing and postnatal teeth
    Sarah Millar; Fiscal Year: 2007
    ..signaling is sufficient to induce expression of Eda and Pitx2, initiate tooth development, induce odontogenic tumors, or regulate the activity of incisor tooth ameloblast precursors...
  4. REGULATION OF EXPRESSION OF THE AMELOGENIN GENES
    CAROLYN GIBSON; Fiscal Year: 1993
    ..In addition, we plan to evaluate certain human odontogenic tumors for expression of amelogenin mRNA, in order to clone human cDNAs to determine whether the human Y-linked ..
  5. The Impact of Fluoride on the Rho Signaling Pathway and the Actin Cytoskeleton
    CAROLYN GIBSON; Fiscal Year: 2007
    ..A better understanding of the health-related benefits and problems associated with environmental fluoride will lead to more informed policy decisions and fundamental knowledge about the impact of this environmental agent. ..
  6. ENAMEL MINERAL FORMATION DURING MURINE ODONTOGENESIS
    CAROLYN GIBSON; Fiscal Year: 2009
    ..Mouse models mimic the human defects and can be used to correlate individual gene mutations with appropriate clinical intervention. ..
  7. ENAMEL MINERAL FORMATION DURING MURINE ODONTOGENESIS
    Carolyn W Gibson; Fiscal Year: 2010
    ..Mouse models mimic the human defects and can be used to correlate individual gene mutations with appropriate clinical intervention. ..
  8. The Role of Semaphorin 4D and Plexin-B1 in Tumor-Induced Angiogenesis.
    John Basile; Fiscal Year: 2009
    ..If successful, our proposed project may uncover an important mechanism for tumor-induced angiogenesis, thereby presenting new targets for the development of anti- angiogenic therapies for the management of aggressive tumors. ..
  9. ENAMEL MINERAL FORMATION DURING MURINE ODONTOGENESIS
    CAROLYN GIBSON; Fiscal Year: 2009
    ..Mouse models mimic the human defects and can be used to correlate individual gene mutations with appropriate clinical intervention. ..
  10. REGULATION OF EXPRESSION OF THE AMELOGENIN GENES
    CAROLYN GIBSON; Fiscal Year: 2001
    ..This is a unique opportunity to study regulation of a sexually dimorphic gene that has a completely tissue specific pattern of expression. ..
  11. ENAMEL MINERAL FORMATION DURING MURINE ODONTOGENESIS
    CAROLYN GIBSON; Fiscal Year: 2006
    ..3) to evaluate LRAP for signal function in vivo and in vitro; and (4) to ascertain additional consequences of absence of amelogenin in maturative ameloblasts, in reparative dentin and during accelerated eruption ..
  12. The Role of Semaphorin 4D and Plexin-B1 in Tumor-Induced Angiogenesis.
    John R Basile; Fiscal Year: 2010
    ..If successful, our proposed project may uncover an important mechanism for tumor-induced angiogenesis, thereby presenting new targets for the development of anti- angiogenic therapies for the management of aggressive tumors. ..