villous adenoma

Summary

Summary: An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)

Top Publications

  1. ncbi Villous adenoma of the appendix. Diagnostic and therapeutic approach
    C M Fernández Blanco
    General Surgery Service A, Complexo Hospitalario Juan Canalejo, A Coruna, Spain
    Rev Esp Enferm Dig 94:537-43. 2002
  2. ncbi Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines
    Fernando S Velayos
    Division of Gastroenterology and Colorectal Cancer Prevention Program, University of California, San Francisco, CA, USA
    Am J Gastroenterol 100:1143-9. 2005
  3. ncbi [The secreting villous adenoma as a rare cause of acute renal failure]
    Jochen Emrich
    St Willibrord Spital, Emmferich am Rehin, France
    Med Klin (Munich) 97:619-23. 2002
  4. ncbi Villous adenoma of the urinary bladder
    Wooseuk Sung
    Department of Urology, School of Medicine, Kyung Hee University, Seoul, Korea
    Int J Urol 15:551-3. 2008
  5. ncbi Treatment strategies and outcomes for rectal villous adenoma from a single-center experience
    Sungeyun David Cho
    Oregon Health and Science University, Portland, OR 97239, USA
    Arch Surg 143:866-70; discussion 871-2. 2008
  6. ncbi A giant villous adenoma case mimicking right colon carcinoma
    Mehmet C Yağmurdur
    Department of General Surgery, Faculty of Medicine, Baskent University, Ankara, Turkey
    Turk J Gastroenterol 15:270-3. 2004
  7. ncbi Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder
    Zhaoli Lane
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:1322-6. 2008
  8. pmc Soft-tissue images. Pseudomyxoma peritonei and villous adenoma of the appendix
    Shiva Jayaraman
    University of Western Ontorio, Department of Pathology, Faculty of Medicine and Dentistry, London
    Can J Surg 45:90-1. 2002
  9. pmc Mucinous adenocarcinoma with superficial stromal invasion and villous adenoma of urachal remnants: a case report
    R Mazzucchelli
    Institute of Pathological Anatomy and Histopathology, Ancona University School of Medicine, 60020 Torrette, Ancona, Italy
    J Clin Pathol 56:465-7. 2003
  10. ncbi Large duodenal villous adenoma requiring head of the pancreas and pylorus-preserving total duodenectomy
    Jorge Cueto
    Department of Surgery, Angeles de las Lomas Hospital, Mexico City, Mexico
    Surg Laparosc Endosc Percutan Tech 15:230-2; discussion 232-3. 2005

Research Grants

Detail Information

Publications211 found, 100 shown here

  1. ncbi Villous adenoma of the appendix. Diagnostic and therapeutic approach
    C M Fernández Blanco
    General Surgery Service A, Complexo Hospitalario Juan Canalejo, A Coruna, Spain
    Rev Esp Enferm Dig 94:537-43. 2002
    Appendix villous adenoma is a rare pathological entity that shows a particular form of clinical presentation that is different from villous adenomas in other places along the gastrointestinal tract.
  2. ncbi Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelines
    Fernando S Velayos
    Division of Gastroenterology and Colorectal Cancer Prevention Program, University of California, San Francisco, CA, USA
    Am J Gastroenterol 100:1143-9. 2005
    ..We sought to determine the rate of MSI in adenomas removed from individuals under 40 yr of age over a 5-yr period in a university general gastroenterology practice...
  3. ncbi [The secreting villous adenoma as a rare cause of acute renal failure]
    Jochen Emrich
    St Willibrord Spital, Emmferich am Rehin, France
    Med Klin (Munich) 97:619-23. 2002
    ..the clinical course, the diagnostics with its difficulties as well as the therapy of the rare secreting villous adenoma with severe electrolyte and fluid depletion syndrome are described...
  4. ncbi Villous adenoma of the urinary bladder
    Wooseuk Sung
    Department of Urology, School of Medicine, Kyung Hee University, Seoul, Korea
    Int J Urol 15:551-3. 2008
    ..We report a new case of a large villous adenoma arising in the bladder that was treated by transurethral resection.
  5. ncbi Treatment strategies and outcomes for rectal villous adenoma from a single-center experience
    Sungeyun David Cho
    Oregon Health and Science University, Portland, OR 97239, USA
    Arch Surg 143:866-70; discussion 871-2. 2008
    To analyze a 13-year, single-surgeon experience with villous adenoma of the rectum with respect to procedure, complications, recurrence, and cancer incidence.
  6. ncbi A giant villous adenoma case mimicking right colon carcinoma
    Mehmet C Yağmurdur
    Department of General Surgery, Faculty of Medicine, Baskent University, Ankara, Turkey
    Turk J Gastroenterol 15:270-3. 2004
    ..Histopathological examinations of sections from colonoscopic biopsy materials on light microscopy revealed villous adenoma morphology...
  7. ncbi Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder
    Zhaoli Lane
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:1322-6. 2008
    ..urachal mucinous adenocarcinoma, 1 nonurachal mucinous and signet ring cell adenocarcinoma, and 1 nonurachal villous adenoma. In conclusion, although all cases of bladder adenocarcinoma examined were negative for PSA and PSAP, the ..
  8. pmc Soft-tissue images. Pseudomyxoma peritonei and villous adenoma of the appendix
    Shiva Jayaraman
    University of Western Ontorio, Department of Pathology, Faculty of Medicine and Dentistry, London
    Can J Surg 45:90-1. 2002
  9. pmc Mucinous adenocarcinoma with superficial stromal invasion and villous adenoma of urachal remnants: a case report
    R Mazzucchelli
    Institute of Pathological Anatomy and Histopathology, Ancona University School of Medicine, 60020 Torrette, Ancona, Italy
    J Clin Pathol 56:465-7. 2003
    This report describes a case of mucinous adenocarcinoma with superficial stromal invasion and villous adenoma originating in the dome of the urinary bladder...
  10. ncbi Large duodenal villous adenoma requiring head of the pancreas and pylorus-preserving total duodenectomy
    Jorge Cueto
    Department of Surgery, Angeles de las Lomas Hospital, Mexico City, Mexico
    Surg Laparosc Endosc Percutan Tech 15:230-2; discussion 232-3. 2005
    ..PPTD should not be used in the presence of malignancy and/or high-grade dysplasia...
  11. ncbi Villous adenoma of the urinary tract: a lesion frequently associated with malignancy
    Jeffrey L Seibel
    Department of Urology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 33:236-41. 2002
    ..6 years and a male preponderance of 67%. In six cases (33%), the lesion was pure villous adenoma. In three cases (17%), there was villous adenoma with in situ adenocarcinoma...
  12. ncbi Villous adenoma of the ureter with manifestation of mucus hydroureteronephrosis
    Chi Min Shih
    Division of Anatomic Pathology, St Joseph s Hospital, Yunlin, Taiwan, R O C
    J Chin Med Assoc 70:33-5. 2007
    Ureteral tumor is prone to result in lumen obstruction. Villous adenoma is most frequently found in the colon and rectum, seldom in the urinary tract and even more rarely in the ureter or pelvis...
  13. ncbi [Renal failure due to a villous adenoma]
    Gitana Acute
    Department of Gastroenterology, Siauliai Hospital, Lithuania
    Medicina (Kaunas) 39:48-50. 2003
    b>Villous adenoma comprises 5.6% of colon tumors. Adenomas of the colon could be divided into tubular, villous, and tubulovillous adenomas...
  14. pmc Gallbladder villous adenoma in a patient with acromegaly: a case report
    Miodrag Krstic
    Clinic for Gastroenterology, Clinical Center of Serbia, 2 Koste Todorovica, Belgrade 11000, Serbia
    World J Gastroenterol 13:3144-6. 2007
    ..An open cholecystectomy was performed and revealed a villous adenoma with several foci of carcinoma in situ...
  15. ncbi Giant villous adenoma presenting as McKittrick-Wheelock syndrome and pseudo-obstruction
    Lachlan F Miles
    The Alfred Hospital, Melbourne, Vic, Australia
    Med J Aust 192:225-7. 2010
    McKittrick-Wheelock syndrome is a rare but recognised complication of hypersecretory rectosigmoid villous adenoma. Fluid and electrolyte imbalances require close monitoring because of large-volume losses of water, sodium and potassium...
  16. ncbi Oncocytic adenocarcinoma of the rectum arising on a villous adenoma with oncocytic features
    Simonetta Piana
    Department of Pathology, Arcispedale Santa Maria Nuova, Viale Risorgimento 80, 42100 Reggio Emilia, Italy
    Virchows Arch 448:228-31. 2006
    ..We describe a case of oncocytic adenocarcinoma of the rectum, associated with a villous adenoma, arising on a 66-year-old man...
  17. ncbi First case of villous adenoma of the appendix leading to acute appendicitis presenting as strangulated femoral hernia: changes in management owing to concurrent adenoma
    A Suppiah
    Academic Surgical Unit, Castle Hill Hospital, Cottingham, East Yorkshire HU16 5JQ, UK
    Hernia 12:95-8. 2008
    ..Appendicectomy and non-mesh hernia repair were performed. Histology revealed acute inflammation and a villous adenoma of the appendix...
  18. ncbi The risk of gastrointestinal malignancies in cystic fibrosis: case report of a patient with a near obstructing villous adenoma found on colon cancer screening and Barrett's esophagus
    C L Alexander
    Gastrointestinal Research Group and Inflammation Research Network, Institute of Infection, Immunity and Inflammation, University of Calgary, Calgary, Alberta, Canada
    J Cyst Fibros 7:1-6. 2008
    ..old male CF patient that underwent a colonoscopy for colon cancer screening and a large, near obstructing, villous adenoma of his ileum was found...
  19. ncbi A prospective study about functional and anatomic consequences of transanal endoscopic microsurgery
    J A Gracia Solanas
    Section of Coloproctology, Department of Surgery B Hospital Clínico Universitario, Zargoza, Spain
    Rev Esp Enferm Dig 98:234-40. 2006
    ..The objective of this study is to analyze the effect of this technique in the anal anatomy and compare with the manometric results...
  20. ncbi Frequency of colorectal polyps in patients with sporadic adenomas or adenocarcinomas of the papilla of vater--an age-matched, controlled study
    A R J Schneider
    Medical Department I, University Hospital, Frankfurt Main, Germany
    Z Gastroenterol 43:1123-7. 2005
    ..Patients with familial adenomatous polyposis bear a particularly increased risk for periampullary tumors. Data on whether the prevalence of colorectal tumors is increased in patients with sporadic ampullary neoplasms are scarce...
  21. ncbi Adenocarcinoma after restorative proctocolectomy for cancer in ulcerative colitis
    Cesare Ruffolo
    Int J Colorectal Dis 22:1557-8. 2007
  22. ncbi Bowel perforation requiring emergency laparotomy and a Hartmann's procedure after a gas explosion induced by argon plasma coagulation
    A P Townshend
    Department of General Surgery, Nottingham City Hospital, Nottingham, United Kingdom
    Endoscopy 39:E1. 2007
  23. ncbi Confined progression of cap polyposis along the anastomotic line, implicating the role of inflammatory responses in the pathogenesis
    Tsuyoshi Konishi
    Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Japan
    Gastrointest Endosc 62:446-7; discussion 447. 2005
  24. ncbi Per-anal excision of large, rectal, villous adenomas
    J M Featherstone
    Department of Colorectal Surgery, Royal Bournemouth Hospital, Bournemouth, UK
    Dis Colon Rectum 47:86-9. 2004
    Considering the malignant potential of villous adenoma of the rectum, complete resection at the first intervention is desirable and yet many series suggest that a high recurrence rate must be expected...
  25. ncbi [Treatment of rectal tumors with transanal endoscopic microsurgery]
    Valdemaras Jotautas
    Center of Abdominal Surgery, Clinic of Gastroenterology and Abdominal Surgery, Vilnius University Hospital Santariskiu klinikos, Santariskiu 2, 08406 Vilnius, Lithuania
    Medicina (Kaunas) 41:470-6. 2005
    ....
  26. ncbi [A double-focus colorectal cancer]
    S Benoist
    Service de Chirurgie Generale et Digestive, Hopital Ambroise Pare, Paris
    J Chir (Paris) 140:353-5. 2003
  27. ncbi Cronkhite-Canada syndrome with adenomatous and carcinomatous transformation of colonic polyp
    Anil Jain
    Department of Medicine, Maulana Azad Medical College, New Delhi 110 002
    Indian J Gastroenterol 22:189-90. 2003
    ..Adenomatous and carcinomatous epithelial changes can occur in Cronkhite-Canada syndrome...
  28. ncbi Local resection for early rectal tumours: Comparative study of transanal endoscopic microsurgery (TEM) versus posterior trans-sphincteric approach (Mason's operation)
    Guo Le Lin
    Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
    Asian J Surg 29:227-32. 2006
    ..To compare local resection of early rectal tumours by transanal endoscopic microsurgery (TEM) and the conventional posterior trans-sphincteric approach (Mason's operation)...
  29. ncbi Mucin-secreting neoplastic polyp: a unique endoscopic presentation of early colon cancer
    K Fu
    Department of Radiology, Dokkyo University School of Medicine, Tochigi, Japan
    Endoscopy 39:E201. 2007
  30. ncbi [General considerations in nodule-aggregating lesions of the colon]
    Tadao Tokoro
    Department of Surgery, Kinki University School of Medicine
    Nihon Rinsho 61:282-5. 2003
  31. ncbi Laparoscopic-assisted colectomy in patients with liver cirrhosis
    J L Martinez
    Department of Gastrointestinal Surgery, Institute of Digestive Diseases, Colorectal Cancer Unit, Hospital Clinic, University of Barcelona, Corporació Sanitaria Clínic, Villarroel 170, 08036, Barcelona, Spain
    Surg Endosc 18:1071-4. 2004
    ..The aim of this study was to evaluate the safety and feasibility of minimal-access surgery in these patients...
  32. ncbi [Effectiveness and patient tolerance of screening colonoscopy -- first results]
    D Hüppe
    Gastroenterologische Schwerpunktpraxis Herne, Herne
    Z Gastroenterol 42:591-8. 2004
    ..It is the aim of this program to reduce the rate of mortality of colorectal cancer (CRC) during the next decade. Up to now no data are available concerning the outcome and patient tolerance of screening colonoscopy...
  33. ncbi Possible mechanism pertinent to mucosal invasion in sporadic colonic adenomas
    C A Rubio
    Gastrointestinal and Liver Pathology Research Laboratory, Department of Pathology, Karolinska Institute and Hospital, Stockholm, Sweden
    Anticancer Res 24:2033-6. 2004
    ..The release of proteolytic secretions through glandular pores in some colonic adenomas disrupt the surrounding matrix, a mechanism that would facilitate neoplastic cell penetration into the lamina propria...
  34. ncbi Diagnostic performance of primary 3-dimensional computed tomography colonography in the setting of colonic diverticular disease
    Matthew F Sanford
    Department of Radiology, University of Wisconsin Medical School, Madison, 53792, USA
    Clin Gastroenterol Hepatol 4:1039-47. 2006
    ..The primary goal of this study was to evaluate the impact of CDD on polyp detection at primary 3-dimensional (3D) CTC...
  35. ncbi Endoscopic transanal resection of rectal tumours using a urological resectoscope--still has a role in selected patients
    G C Beattie
    Department of Surgery, Ulster Community and Hospitals Trust, Dundonald, Belfast, UK
    Colorectal Dis 7:47-50. 2005
    ..This study reports our experience of treating rectal lesions with endoscopic transanal resection (ETAR) using the urological resectoscope...
  36. ncbi Local excision of rectal polyp: indications and techniques
    C Fucini
    Clinica Chirurgica I, Universita degli Studi di Firenze, Viale Morgagni, Florence, Italy
    Tech Coloproctol 8:s300-4. 2004
    ..Among these procedures, transanal endoscopic microsurgery is gaining a primary role in many circumstances...
  37. ncbi The Kraske procedure: a critical analysis of a surgical approach for mid-rectal lesions
    Mark Onaitis
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Surg Oncol 94:194-202. 2006
    ..To analyze the Kraske procedure as an approach to mid-rectal disease...
  38. ncbi [Results of coloscopy screening in 2005--an Internet-based documentation]
    A Sieg
    Fachpraxis für Gastroenterologie Heidelberg, Römerstrasse 7, 69115 Heidelberg
    Dtsch Med Wochenschr 131:379-83. 2006
    ..In October 2002 screening coloscopy was introduced into the National Cancer Prevention Programme in Germany. The results of an online registry are presented here...
  39. ncbi PET imaging of concomitant colonic hyperplastic polyp and tubulovillous adenoma
    Ba D Nguyen
    Department of Radiology, Mayo Clinic Scottsdale, Arizona 85259, USA
    Clin Nucl Med 30:48-50. 2005
  40. ncbi Incidence of advanced adenomas at surveillance colonoscopy in patients with a personal history of colon adenomas: a meta-analysis and systematic review
    Sameer D Saini
    Division of Gastroenterology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
    Gastrointest Endosc 64:614-26. 2006
    ..Guidelines recommend longer intervals between surveillance colonoscopies for low-risk patients, but physicians frequently perform surveillance colonoscopy at shorter intervals for these patients...
  41. ncbi Role of matrix metalloproteinase-7 in colorectal adenomas
    Hale Kirimlioglu
    Department of Surgery, GIT Transplantation Division, Inonu University Medical School, Turgut Ozal Tip Merkezi, Malatya, 44069, Turkey
    Dig Dis Sci 51:2068-72. 2006
    ..In conclusion, MMP-7 overexpression is thought to be an early event in the adenoma-carcinoma pathway...
  42. ncbi KRAS transitions and villous growth in colorectal adenomas
    Mauro Risio
    Cell Oncol 27:363-6. 2005
  43. ncbi Villous adenocarcinoma of the colon and rectum: a clinicopathologic study of 36 cases
    Timothy S Loy
    Department of Pathology, University of Missouri School of Medicine, Columbia, MO 65212, USA
    Am J Surg Pathol 28:1460-5. 2004
    ..Classifying these tumors as a special type of colorectal cancer may facilitate the development of diagnostic adjuncts and optimal treatment protocols...
  44. ncbi Most dysplasia in ulcerative colitis is visible at colonoscopy
    Matthew D Rutter
    St Mark s Hospital, Harrow, London, United Kingdom
    Gastrointest Endosc 60:334-9. 2004
    ..It was hypothesized by us that most dysplasia is actually colonoscopically visible. This study assessed the proportion of dysplasia that has been detected macroscopically in patients who underwent colonoscopy surveillance at our center...
  45. ncbi A case of colorectal carcinoma in adenoma analyzed by a cDNA array
    Katsuhiko Nosho
    First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
    Int J Colorectal Dis 20:287-91. 2005
    ..To clarify relevant alterations of gene expression associated with adenoma-carcinoma progression, the gene expression profiles of these tumor tissues were analyzed by a cDNA array...
  46. ncbi Prospective study of the functional results of transanal endoscopic microsurgery
    Huann Sheng Wang
    Division of Colon and Rectal Surgery, Department of Surgery, Veterans General Hospital Taipei, National Yang Ming University School of Medicine, Taipei, Taiwan, R O C
    Hepatogastroenterology 50:1376-80. 2003
    ..Most clinical research addresses the technological advances and oncological outcomes of transanal endoscopic microsurgery. Our aim was to examine the functional results...
  47. ncbi Screening colonoscopy in the asymptomatic 50- to 59-year-old population
    A Mehran
    Department of Surgery, Cleveland Clinic Florida, 6101 Pine Ridge Road, Naples, FL 34119, USA
    Surg Endosc 17:1974-7. 2003
    ..We therefore reviewed our institution's colonoscopy experience with asymptomatic 50- to 59-year-olds, with negative fecal occult blood tests and negative family histories...
  48. ncbi [Concurrent rectal cancer and extensive right colon villous adenoma]
    L Maggiori
    Service de Chirurgie Digestive, Hopital Ambroise Pare, Boulogne Billancourt
    J Chir (Paris) 145:70-5. 2008
  49. ncbi High-grade dysplasia and invasive carcinoma in colorectal adenomas: a multivariate analysis of the impact of adenoma and patient characteristics
    Michael Gschwantler
    4th Department of Internal Medicine, KA Rudolfstiftung, Vienna, Austria
    Eur J Gastroenterol Hepatol 14:183-8. 2002
    ..e. high-grade dysplasia or invasive carcinoma) in colorectal adenomas. A secondary goal was to assess the malignant potential of adenomas with a diameter of < 0.5 cm...
  50. ncbi The significance of beta-catenin, E-cadherin, and P-cadherin expressions in neoplastic progression of colorectal mucosa: an immunohistochemical study
    Berna Savas
    Ankara University Medical Faculty, Ankara, Turkey
    Acta Gastroenterol Belg 70:339-44. 2007
    ..The purpose of the current study was to investigate the role of beta-catenin, E-cadherin and P-cadherin in colorectal carcinogenesis using tissue array method...
  51. ncbi [Coloanal anastomosis in rectal cancer surgery]
    Giedre Rudinskaite
    Kauno medicinos universitetas, Mickeviciaus 9, 3000 Kaunas
    Medicina (Kaunas) 38:624-30. 2002
    ..To determine the efficacy of proctectomy with coloanal anastomosis for adenocarcinoma of the lower third of the rectum, and to compare quality of life after colonal anatomosis with low anterior rectal resection...
  52. ncbi A program to enhance completion of screening colonoscopy among urban minorities
    Lea Ann Chen
    Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Clin Gastroenterol Hepatol 6:443-50. 2008
    ..This study investigated the use of patient navigation within an open-access referral system and its effects on colonoscopy completion rates among urban minorities...
  53. ncbi Clinical significance of small colorectal adenoma less than 10 mm: the KASID study
    Tae Woo Yoo
    Department of Internal Medicine, Kangbuk Samsung Hospital, Korea
    Hepatogastroenterology 54:418-21. 2007
    ..We evaluated the clinical significance of polypectomy in cases of small colorectal adenomas, measuring less than 10 mm...
  54. ncbi [Trans-anal resection of low rectal neoplasms]
    S Di Mauro
    Divisione di Chirurgia Generale IV, Cattedra di Chirurgia Generale, , Messina, Italy
    Minerva Chir 56:119-24. 2001
    ..But even in this case, and in more advanced situations, this method allows mortality due to occlusive complications to be reduced and ensures a better quality of residual life...
  55. ncbi Laparoscopy-assisted endoscopic mucosal resection in the colon: a preliminary report
    Maria Alessandra Filograna
    Department of Surgery V Bonomo, Bari University, Bari
    Chir Ital 60:279-84. 2008
    ..The patients presented no complications and no recurrence was observed during the subsequent follow-up...
  56. ncbi Prophylactic clip application does not decrease delayed bleeding after colonoscopic polypectomy
    Kazuhiko Shioji
    The Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Japan
    Gastrointest Endosc 57:691-4. 2003
    ..This randomized controlled trial evaluated the efficacy of prophylactic clip application for prevention of delayed postpolypectomy bleeding...
  57. ncbi The Immunohistochemical expression of endothelial cell differentiation gene-2 receptor in human colorectal adenomas
    Yasuhiro Komuro
    Department of Surgical Oncology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Hepatogastroenterology 50:1770-3. 2003
    ..In the current study, we examined the immunohistochemical expression of EDG-2 in colorectal mucosa and adenoma, and clarified its relation with the clinicopathological features...
  58. ncbi [Hydro-saline depletion syndrome secondary to villous adenoma of the rectum: mechanism of secretion. A case report]
    A Corbatón Anchuelo
    Rev Esp Enferm Dig 95:159-60. 2003
  59. ncbi Infectious endocarditis from Streptococcus bovis associated with colonic carcinoma: case report and literature review
    Jaques Waisberg
    Surgical Gastroenterology, Hospital do Servidor Publico Estadual, Brasil
    Arq Gastroenterol 39:177-80. 2002
    ..Bacteremia and infectious endocarditis from Streptococcus bovis may be related to the presence of neoplastic lesions in the large intestine and hepatic disease...
  60. ncbi The efficacy of intravenous contrast-enhanced 16-raw multidetector CT colonography for detecting patients with colorectal polyps in an asymptomatic population in Korea
    Young Sun Kim
    Seoul National University Hospital, Healthcare System Gangnam Center, Healthcare Research Institute, Seoul, Korea
    J Clin Gastroenterol 42:791-8. 2008
    ....
  61. ncbi Expression of p185 and p53 in benign and malignant colorectal lesions
    B Porcelli
    Institute of Biochemistry and Enzymology, University of Siena, Italy
    Histochem J 33:51-7. 2001
    ..Although there was no correlation between p185 and p53 expression in premalignant lesions and adenocarcinomas, these two proteins have an important role in the adenoma-carcinoma sequence...
  62. ncbi Survival of elderly persons undergoing colonoscopy: implications for colorectal cancer screening and surveillance
    Charles J Kahi
    Indiana University Medical Center, Roudebush Veterans Affairs Medical Center, Indiana University Department of Biostatistics, Indianapolis, Indiana 46202, USA
    Gastrointest Endosc 66:544-50. 2007
    ..In the elderly, the increased prevalence of colorectal neoplasia and the protective effect of colonoscopy may be offset by advancing age and comorbidity...
  63. ncbi Primary mucin-producing urothelial-type adenocarcinoma of prostate: report of 15 cases
    Adeboye O Osunkoya
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 31:1323-9. 2007
    ..of the prostatic urethral urothelium and subsequent in situ adenocarcinoma sometimes associated with villous adenoma. These prostatic adenocarcinomas are analogous to nonurachal adenocarcinomas arising in the bladder from ..
  64. ncbi Tumor of the ampulla of Vater: experience with local or radical resection in 171 consecutively treated patients
    H G Beger
    Department of General Surgery, University of Ulm, Germany
    Arch Surg 134:526-32. 1999
    ..We hypothesized that, in malignant lesions of the ampulla, the T and N stages are major determinants of the patient's long-term outcome...
  65. ncbi Performance of computed tomographic colonography for the screening of colorectal polyp in acromegalic patients: a prospective study
    Odery Ramos
    Department of Gastroenterology, Faculdade de Medicina, Universidade Federal do Parana, Curitiba, PR, Brazil
    Arq Gastroenterol 46:90-6. 2009
    ..Computed tomographic colonography, also known as virtual colonoscopy, is an innovative and secure technology which is revolutionizing the diagnosis of colon and rectum neoplasias...
  66. ncbi Risk factors for advanced colonic neoplasia and hyperplastic polyps in asymptomatic individuals
    David A Lieberman
    Division of Gastroenterology, Department of Veterans Affairs Medical Center, Portland, Ore 97207, USA
    JAMA 290:2959-67. 2003
    ..Few studies have evaluated risk factors for advanced colorectal neoplasia in asymptomatic individuals, compared risk factors between persons with and without polyps, or included most purported risk factors in a multivariate analysis...
  67. ncbi Significance of missed polyps at CT colonography
    Michael Macari
    Department of Radiology, Abdominal Imaging, NYU Medical Center, Tisch Hospital, 560 First Ave, Ste HW 207, New York, NY 10016, USA
    AJR Am J Roentgenol 183:127-34. 2004
    ..In these cases, follow-up conventional colonoscopy was offered...
  68. ncbi Outcome of laparoscopic colectomy for polyps not suitable for endoscopic resection
    Naveen Pokala
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, OH 44106 5047, USA
    Surg Endosc 21:400-3. 2007
    ..This approach eradicates the polyp and allows an oncologic resection should the polyp prove to be malignant. The purpose of this study was to assess outcomes of a laparoscopic approach for the management of these polyps...
  69. pmc Pancreas-sparing distal duodenectomy for infrapapillary neoplasms
    D R C Spalding
    Department of Surgery, Hammersmith Hospital, London, UK
    Ann R Coll Surg Engl 89:130-5. 2007
    ....
  70. ncbi Fluorescence endoscopy using a fluorescein-labeled monoclonal antibody against carcinoembryonic antigen in patients with colorectal carcinoma and adenoma
    R Keller
    Department of Medicine B, University of Munster, Munster, Germany
    Endoscopy 34:801-7. 2002
    ..This study reports an endoscopic technique using locally applied fluorescein-labeled antibodies for in-vivo detection of colorectal dysplasia and carcinoma...
  71. ncbi Is pylorospasm a cause of delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy?
    Dong K Kim
    Department of Surgery, Winthrop University Hospital, Mineola, New York 11501, USA
    Ann Surg Oncol 12:222-7. 2005
    ..We hypothesized that DGE may be due to pylorospasm secondary to vagal injuries at operation and may be preventable by the addition of pyloromyotomy...
  72. pmc Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma
    Takako Kawasaki
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    BMC Cancer 8:33. 2008
    ..Therefore, we hypothesized that COX-2 may play a less important role in the serrated pathway...
  73. ncbi Risk of colorectal cancer following colonoscopic polypectomy
    L Bertario
    Digestive Surgical Department, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
    Tumori 85:157-62. 1999
    ..To follow a cohort of patients who had undergone polypectomies in order to assess the overall risk of subsequent colorectal cancer in relation with various adenomas characteristics...
  74. pmc A Giant Mucinous Adenocarcinoma Arising within a Villous Adenoma of the Urachus: Case Report and Review of the Literature
    Steven Joniau
    Department of Urology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium
    Case Report Med 2009:818646. 2009
    We present an exceptional case of a giant urachal tumor, consisting of both villous adenoma and mucinous adenocarcinoma of the urachus. The tumor was incidentally discovered during investigations for renal failure...
  75. pmc Successful photodynamic therapy for biliary papillomatosis: a case report
    Lars P Bechmann
    Department of Medicine, Division of Gastroenterology and Hepatology, University of Essen, Hufeland Street 55, Essen D 45122, Germany
    World J Gastroenterol 14:4234-7. 2008
    ..A previously healthy 65-years old male developed jaundice and right upper abdominal quadrant pain in 1996. A villous adenoma of the distal bile duct was diagnosed. A Whipple procedure was performed...
  76. pmc Double balloon enteroscopy in children: diagnosis, treatment, and safety
    Mike Thomson
    Centre for Paediatric Gastroenterology, Sheffield Children s NHS Foundation Trust, Sheffield, S10 2TH, United Kingdom
    World J Gastroenterol 16:56-62. 2010
    ..To assess the feasibility and utility of double balloon enteroscopy (DBE) in the management of small bowel diseases in children...
  77. ncbi Findings at follow-up endoscopies in subjects with suspected colorectal abnormalities: effects of baseline findings and time to follow-up
    Fay H Cafferty
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, England
    Cancer J 13:263-70. 2007
    ..The risk of various outcomes at the second examination is assessed according to findings at the first examination and the interval between examinations...
  78. pmc Large endoscopic mucosal resection for colorectal tumors exceeding 4 cm
    Philippe Ah Soune
    Department of Gastroenterology, Hopital Nord, Chemin des Bourrely, 13915 Marseille Cedex 20, France
    World J Gastroenterol 16:588-95. 2010
    ..To evaluate the feasibility and the outcome of endoscopic mucosal resection (EMR) for large colorectal tumors exceeding 4 cm (LCRT) undergoing piecemeal resection...
  79. ncbi Potential biomarkers of colorectal adenoma-dysplasia-carcinoma progression: mRNA expression profiling and in situ protein detection on TMAs reveal 15 sequentially upregulated and 2 downregulated genes
    Orsolya Galamb
    2nd Department of Medicine, Semmelweis University, Szentkiralyi str 46, Budapest, Hungary
    Cell Oncol 31:19-29. 2009
    ..As most colorectal cancers (CRC) develop from villous adenomas, studying alterations in gene expression profiles across the colorectal adenoma-dysplasia-carcinoma sequence may yield potential biomarkers of disease progression...
  80. ncbi How often is a positive faecal occult blood test the result of coeliac disease?
    Richard F A Logan
    Department of Epidemiology and Public Health, University Hospital, University of Nottingham, Nottingham, UK
    Eur J Gastroenterol Hepatol 15:1097-100. 2003
    ..This study examines whether a positive FOB is a feature of coeliac disease and whether FOB-positive subjects need investigation for coeliac disease...
  81. pmc Ki-67: a useful marker for the evaluation of dysplasia in ulcerative colitis
    S N Andersen
    Institute of Forensic Medicine, National Hospital, University of Oslo, Norway
    Mol Pathol 51:327-32. 1998
    ..Therefore, the aim of this study was to search for a more objective parameter to help distinguish regenerative changes from epithelial dysplasia...
  82. ncbi [Villous adenoma within an urachal diverticulum associated with long-term mucusuria]
    S Macher-Goeppinger
    Institut fur Pathologie, Universitat Heidelberg, Im Neuenheimer Feld 220, 69120, Heidelberg
    Pathologe 29:305-7. 2008
    ..After surgical resection histologic examination showed a mucus producing, intestinally differentiated adenoma within the diverticulum. This finding explains both the recurrent infections and the 10-year history of mucusuria...
  83. ncbi Magnification chromo-colonoscopy
    Kazutomo Togashi
    Division of Endoscopy, Omiya Medical Center, Jichi Medical University, Japan
    ANZ J Surg 76:1101-5. 2006
    ..on histological characterization of normal mucosa, hyperplastic polyp, polypoid adenoma, flat adenoma, tubulo-villous adenoma and cancerous tissue, respectively. In previous reports, overall accuracy ranged from 80 to 95%...
  84. ncbi Optical biopsy system distinguishing between hyperplastic and adenomatous polyps in the colon during colonoscopy
    Zdenek Benes
    Thomayer Teaching Hospital, Videnska 800, 140 00 Prague 4, Czech Republic
    Anticancer Res 29:4737-9. 2009
    ..The aim was to determine the correlation between the results of an optical biopsy system and the histopathology report of the physical biopsy specimens of the same polyps removed at colonoscopy...
  85. ncbi Symptomatic ileocolic fistula as a complication of endoscopic laser therapy. A case report
    L Bataille
    Gastroenterology Unit, Hospital St Joseph, 6, rue de la Duchère, 6060 Gilly, Belgium
    Acta Gastroenterol Belg 65:176-8. 2002
    ..hemorrhage, stenosis and perforation are well documented but ileocolic fistulas after laser therapy for a villous adenoma have been rarely reported. We report the case of a patient with diarrhea related to an ileocecal fistula...
  86. ncbi Evaluation of the immunohistochemical stain patterns of survivin, Bak and Bag-1 in colorectal cancers and comparison with polyps situated in the colon
    Murat Alper
    Diskapi Hospital, Pathology Department, Ankara, Turkey
    Hepatogastroenterology 55:1269-73. 2008
    ..Colorectal cancer is one of the most common cancers worldwide. The adenoma-carcinoma sequence in colorectal cancer has been documented approximately; however, several series of molecular mechanisms still require elucidation...
  87. ncbi Association of serum lipids and apolipoprotein E gene polymorphism with the risk of colorectal adenomas
    Zhou Zhongyin
    Department of Gastroenterology, Renmin Hospital, Wuhan University, Hubei, Peoples Republic of China
    Saudi Med J 27:161-4. 2006
    ..To investigate the relationship of serum lipids and apolipoprotein (apoE) gene polymorphism to colorectal adenomas...
  88. ncbi Incidental finding of colorectal cancer in screening colonoscopy and its cost effectiveness
    Chichi Berhane
    Department of Surgery, Joan C Edwards School of Medicine, Marshall University, 1600 Medical Center Drive, Suite 2600, Huntington, WV 25701, USA
    Am Surg 75:699-703; discussion 703-4. 2009
    ..Fourteen per cent had hyperplastic polyps, 15 per cent had tubular adenoma, and 8.6 per cent villous adenoma. Adenoma with high grade dysplasia was found in 6.6 per cent, and 5.5 per cent had nonadenomatous lesions...
  89. ncbi [Minimally invasive treatment of synchronous colorectal tumours]
    Roberto Cirocchi
    Clinica Chirurgica Generale d Urgenza, Universita degli Studi di Perugia, Azienda Ospedaliera di Terni
    Chir Ital 60:237-41. 2008
    ..cancer followed by a laparoscopic right hemicolectomy with an extracorporeal anastomosis for a voluminous villous adenoma (1 patient) and laparoscopic right hemicolectomy with an extracorporeal anastomosis for cancer followed by ..
  90. pmc AMACR is associated with advanced pathologic risk factors in sporadic colorectal adenomas
    Sotiris Lakis
    Laboratory of Pathology, Georgios Gennimatas General Hospital, Thessaloniki 54635, Greece
    World J Gastroenterol 16:2476-83. 2010
    ..To analyze alpha-methylacyl CoA racemase (AMACR) expression in relation to various dysplasia phenotypes and clinicopathological parameters of sporadic colorectal adenomas...
  91. ncbi Treatment of a nephrotic syndrome by endoscopic removal of a villous adenoma of the duodenum
    S de Decker
    Service de Geriatrie, centre hospitalier régional de Citadelle, boulevard de 12e de ligne 1, 4000 Liege, Belgium
    Gastroenterol Clin Biol 34:625-8. 2010
    We report the case of a patient diagnosed with a villous adenoma of the duodenum showing high degree dysplasia who developed a nephrotic syndrome (NS) due to a membranous nephropathy (MN), demonstrated by renal biopsy...
  92. pmc Pancreatitis complicating mucin-hypersecreting common bile duct adenoma
    Panagiotis Katsinelos
    Department of Endoscopy and Motility Unit, G Gennimatas Hospital, Ethnikis Aminis 41, Thessaloniki 54635, Greece
    World J Gastroenterol 12:4927-9. 2006
    ..He underwent a modified Whipple operation and histological examination of the surgical specimen showed villous adenoma with rich secretion of mucus.
  93. ncbi [Therapeutic effects of transsphincteric surgery in treating rectal tumors: a report of 97 cases]
    Hui Zhong Qiu
    Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
    Zhonghua Wai Ke Za Zhi 45:1167-9. 2007
    ..To evaluate the role of transsphincteric surgery in local excision of mid and lower rectal tumors...
  94. ncbi Overexpression of an mRNA-binding protein in human colorectal cancer
    J Ross
    McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin Madison, 1400 University Avenue, Madison, WI 53706, USA
    Oncogene 20:6544-50. 2001
    ..exception, normal colon specimens were negative for CRD-BP expression; specimens of inflammatory bowel and a villous adenoma also had no detectable CRD-BP...
  95. ncbi Pancreas-sparing duodenectomy: technique and indications
    L Lundell
    Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
    Eur J Surg 168:74-7. 2002
    ..To assess the feasibility, safety, and short-term functional outcome of a pancreas-sparing duodenectomy...
  96. ncbi Four percent of patients undergoing colorectal cancer surgery may have synchronous appendiceal neoplasia
    Muhammad Najm Khan
    Department of Colorectal Surgery, North Hampshire Hospital NHS Trust, Basingstoke, RG24 9NA, United Kingdom
    Dis Colon Rectum 50:1856-9. 2007
    ..A special interest of the senior author in appendiceal and rectal cancer has prompted routine removal of the appendix in all cases undergoing surgery for colorectal cancer...
  97. ncbi Diagnostic accuracy and tolerability of contrast enhanced CT colonoscopy in symptomatic patients with increased risk for colorectal cancer
    Yelda Ozsunar
    Department of Radiology, School of Medicine, Adnan Menderes University, Aydin, Turkey
    Eur J Radiol 71:513-8. 2009
    ....
  98. ncbi Predictive value of diminutive colonic adenoma trial: the PREDICT trial
    Philip Schoenfeld
    Division of Gastroenterology, University of Michigan School of Medicine, and VA Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48105, USA
    Clin Gastroenterol Hepatol 1:195-201. 2003
    ..Diminutive adenomas (1-9 mm in diameter) are frequently found during colon cancer screening with flexible sigmoidoscopy (FS). This trial assessed the predictive value of these diminutive adenomas for advanced adenomas in the proximal colon...
  99. ncbi Microsatellite instability in long-standing ulcerative colitis
    Tone Løvig
    Institute of Forensic Medicine, Department of Pathology, Akershus University Hospital HF, Lørenskog, Norway
    Scand J Gastroenterol 42:586-91. 2007
    ..Concerning microsatellite instability (MSI), many contradictory results have been published. We therefore analysed a large, well-characterized UC material for MSI to elucidate its significance in long-standing UC...
  100. ncbi Large intestinal type-urachal adenocarcinoma with focal expression of prostatic specific antigen
    Haruaki Kato
    Department of Urology, Shinshu University School of Medicine, Matsumoto, Japan
    Int J Urol 11:1033-5. 2004
    We present a case of colonic-type adenocarcinoma, which might arise from an urachal remnant through a villous adenoma. The cancer tissue in the present case showed focal immunoreaction to prostate-specific antigen (PSA)...
  101. ncbi [Endoscopic laser therapy in gastroenterology--physical-technical principles and applications]
    K H Donnerhacke
    Carl Zeiss Jena, Betrieb für Entwicklung wissenschaftlich technischer Erzeugnisse, Friedrich Schiller Universitat Jena
    Z Gesamte Inn Med 45:611-6. 1990
    ..In 12 out of 15 patients with a villous adenoma of the rectum the treatment was successful...

Research Grants8

  1. Colon Polyp Surveillance with DNA Analysis of Stool
    Philip Schoenfeld; Fiscal Year: 2003
    ..accuracy of fecal MTAP for colorectal cancers and advanced adenomas (adenoma> 10 mm in diameter, villous adenoma, or adenoma with high-grade dysplasia) among a cohort of patients with a personal history of colon adenomas; ..
  2. CORI: Consortium Expansion and Database Enhancement
    David Lieberman; Fiscal Year: 2004
    ....
  3. Screening for colortectal cancer in an Asian Community Center
    David Lieberman; Fiscal Year: 2008
    ..This is a new paradigm for screening, which takes advantage of the trust and cultural awareness that exists at the community center and does not rely on the primary care provider. [unreadable] [unreadable] [unreadable] [unreadable]..
  4. Human RNA Binding Protein as a Cancer Marker
    Jeffrey Ross; Fiscal Year: 2003
    ..They might also stimulate future studies to evaluate the CRD-BP as a therapeutic target. ..
  5. Role of an RNA-Binding Protein in Mammary Carcinogenesis
    Jeffrey Ross; Fiscal Year: 2009
    ..By investigating the oncogenic properties of the CRD-BP, the RNAs it affects in vivo, and its interactions with tumor-inducing genetic and environmental factors, we hope to uncover novel tumorigenesis pathways. ..