melanotic neuroectodermal tumor

Summary

Summary: A benign, rapidly growing, deeply pigmented tumor of the jaw and occasionally of other sites, consisting of an infiltrating mass of cells arranged in an alveolar pattern, and occurring almost exclusively in infants. Its source of origin is in dispute, the various theories giving rise to its several names. (Dorland, 27th ed)

Top Publications

  1. ncbi December 2004: one-year-old girl with aggressive skull tumor
    Merdas Al-Otaibi
    Brain Pathol 15:171-3. 2005
  2. doi Melanotic neuroectodermal tumor of infancy: review of literature and case report
    Heba Selim
    Department of Oral and Maxillofacial Surgery, Ain Shams University School of Dentistry, Cairo 11381, Egypt
    J Pediatr Surg 43:E25-9. 2008
  3. ncbi Successful chemotherapy for melanotic neuroectodermal tumor of infancy in a baby
    Willi Woessmann
    Med Pediatr Oncol 40:198-9. 2003
  4. ncbi Establishment and characterization of new cell lines derived from melanotic neuroectodermal tumor of infancy arising in the mandible
    Hamdy Metwaly
    Division of Oral Pathology, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    Pathol Int 55:331-42. 2005
  5. doi Recurrent melanotic neuroectodermal tumor of infancy: a proposal for treatment protocol with surgery and adjuvant chemotherapy
    Johannus Neven
    Oral and Maxillofacial Surgeon, Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:493-6. 2008
  6. doi Melanotic neuroectodermal tumor of infancy: 2 decades of clinical experience with 18 patients
    Amit Chaudhary
    Department of Surgery, King George Medical University, Lucknow, India
    J Oral Maxillofac Surg 67:47-51. 2009
  7. ncbi Gigantiform melanotic neuroectodermal tumor of infancy
    M M Bouckaert
    Department of Maxillofacial and Oral Surgery, Faculty of Dentistry, Medical University of Southern Africa, Pretoria, South Africa
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86:569-72. 1998
  8. ncbi Melanotic neuroectodermal tumor of infancy involving the mandible: 7-year follow-up after hemimandibulectomy and costochondral graft reconstruction
    A Eckardt
    Department of Maxillofacial Surgery, Hannover Medical School, Germany
    J Craniofac Surg 12:349-54. 2001
  9. ncbi The operating microscope in the management of melanotic neuroectodermal tumor of infancy
    G G Carnevale
    Department of Otolaryngology and Communicative Sciences, State University of New York Health Science Center, Syracuse, NY 13210, USA
    Am J Otolaryngol 22:76-9. 2001
  10. ncbi Subtotal maxillectomy for melanotic neuroectodermal tumor of infancy
    B A Mast
    Department of Pathology of the University of Pittsburgh Medical Center, and Children s Hospital of Pittsburgh, PA, USA
    Plast Reconstr Surg 103:1961-3. 1999

Scientific Experts

Detail Information

Publications105 found, 100 shown here

  1. ncbi December 2004: one-year-old girl with aggressive skull tumor
    Merdas Al-Otaibi
    Brain Pathol 15:171-3. 2005
    ..The overall histological features are consistent with a rare malignant variant of a melanotic neuroectodermal tumor of infancy.
  2. doi Melanotic neuroectodermal tumor of infancy: review of literature and case report
    Heba Selim
    Department of Oral and Maxillofacial Surgery, Ain Shams University School of Dentistry, Cairo 11381, Egypt
    J Pediatr Surg 43:E25-9. 2008
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon, fast-growing, pigmented neoplasm of neural crest origin. It primarily affects the maxilla of the infants during the first year of life...
  3. ncbi Successful chemotherapy for melanotic neuroectodermal tumor of infancy in a baby
    Willi Woessmann
    Med Pediatr Oncol 40:198-9. 2003
  4. ncbi Establishment and characterization of new cell lines derived from melanotic neuroectodermal tumor of infancy arising in the mandible
    Hamdy Metwaly
    Division of Oral Pathology, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    Pathol Int 55:331-42. 2005
    Three cell systems (MINT1/2/3) derived from a melanotic neuroectodermal tumor of infancy (MNTI) arising in the mandible of a 1-month-old newborn boy have been established, and their cytological natures have been characterized...
  5. doi Recurrent melanotic neuroectodermal tumor of infancy: a proposal for treatment protocol with surgery and adjuvant chemotherapy
    Johannus Neven
    Oral and Maxillofacial Surgeon, Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:493-6. 2008
    ..a 4-month-old male infant treated with combined surgery and chemotherapy for an aggressive recurrent melanotic neuroectodermal tumor of infancy (MNTI) on the top of the alveolar process of the mandible with a long-term follow-up is ..
  6. doi Melanotic neuroectodermal tumor of infancy: 2 decades of clinical experience with 18 patients
    Amit Chaudhary
    Department of Surgery, King George Medical University, Lucknow, India
    J Oral Maxillofac Surg 67:47-51. 2009
    The purpose of this article is to report our experience in the management of 18 patients with melanotic neuroectodermal tumor of infancy involving the maxillary alveolus.
  7. ncbi Gigantiform melanotic neuroectodermal tumor of infancy
    M M Bouckaert
    Department of Maxillofacial and Oral Surgery, Faculty of Dentistry, Medical University of Southern Africa, Pretoria, South Africa
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86:569-72. 1998
    b>Melanotic neuroectodermal tumor of infancy is a rare neoplasm of possibly neural crest origin, and it predominantly occurs in the premaxillas of infants less than 12 months old...
  8. ncbi Melanotic neuroectodermal tumor of infancy involving the mandible: 7-year follow-up after hemimandibulectomy and costochondral graft reconstruction
    A Eckardt
    Department of Maxillofacial Surgery, Hannover Medical School, Germany
    J Craniofac Surg 12:349-54. 2001
    ..We report a case of a 6-months old female infant suffering from a melanotic neuroectodermal tumor of infancy involving the mandible...
  9. ncbi The operating microscope in the management of melanotic neuroectodermal tumor of infancy
    G G Carnevale
    Department of Otolaryngology and Communicative Sciences, State University of New York Health Science Center, Syracuse, NY 13210, USA
    Am J Otolaryngol 22:76-9. 2001
    b>Melanotic neuroectodermal tumor of infancy is a rare condition that is most commonly found within the head and neck regions. We present a 4-month-old boy with a melanotic neuroectodermal tumor of infancy of his maxilla...
  10. ncbi Subtotal maxillectomy for melanotic neuroectodermal tumor of infancy
    B A Mast
    Department of Pathology of the University of Pittsburgh Medical Center, and Children s Hospital of Pittsburgh, PA, USA
    Plast Reconstr Surg 103:1961-3. 1999
    b>Melanotic neuroectodermal tumor of infancy is a rare pigmented neoplasm occurring in infants before 1 year of age. It is a rapidly growing tumor that most frequently affects the craniofacial skeleton...
  11. ncbi Melanotic neuroectodermal tumor of infancy: report of two cases and review of literature
    S Kaya
    Department of Otolaryngology Head and Neck Surgery, Hacettepe University Medical Faculty, Ankara, Turkey
    Int J Pediatr Otorhinolaryngol 52:169-72. 2000
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, distinctive neoplasm containing melanin; it primarily affects the maxilla of the infants during the first year of life...
  12. ncbi Melanotic neuroectodermal tumor of infancy. Report of a case
    S Anil
    Dept of Periodontia Dental College, Trivandrum, India
    Indian J Dent Res 4:65-7. 1993
    A case of melanotic neuroectodermal tumor of infancy involving the right maxillary alveolar ridge region of a 4 month old girl is reported. Clinical, histopathological and laboratory findings supported the diagnosis...
  13. ncbi Melanotic neuroectodermal tumor of infancy: a molecular genetic study
    M Khoddami
    Department of Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Dev Pathol 1:295-9. 1998
    b>Melanotic neuroectodermal tumor of infancy is a rare but well-recognized entity in pediatric pathology...
  14. ncbi A clinicopathologic and immunohistochemical analysis of melanotic neuroectodermal tumor of infancy
    A W Barrett
    Oral and Maxillofacial Pathology Unit, Eastman Denatal Institute for Oral Healthcare Sciences, University College, London, United Kingdom
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93:688-98. 2002
    The purpose of this study was to review the features of 8 cases of melanotic neuroectodermal tumor of infancy (MNTI) of the jaws with respect to the expression of NB84, CD99, PGP 9...
  15. ncbi Melanotic neuroectodermal tumor of infancy in the skull associated with high serum levels of catecholamine. Case report
    S Hoshino
    Department of Neurosurgery, Nippon Medical School, Tokyo, Japan
    J Neurosurg 80:919-24. 1994
    The case of a 5-month-old boy with a left retromastoid melanotic neuroectodermal tumor of infancy is presented. The tumor extended from the subcutaneous tissue of the occiput to the cerebellar hemisphere...
  16. ncbi Melanotic neuroectodermal tumor of infancy in the mandible: report of a case
    Y Hoshina
    Niigata University, First Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Niigata University, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 89:594-9. 2000
    A case of melanotic neuroectodermal tumor of infancy occurring in the mandible is described. The patient was a 1-month-old boy with a rapidly growing tumor of the mandible...
  17. ncbi Melanotic neuroectodermal tumor of infancy: systematic review of the literature and presentation of a case
    Birgit Kruse-Losler
    Department of Craniomaxillofacial Surgery, University of Muenster, Muenster, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:204-16. 2006
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, distinctive neoplasm of early infancy with rapid expansile growth and a high rate of recurrences...
  18. ncbi Melanotic neuroectodermal tumor in a newborn
    Onder Tan
    Ataturk University, Medical Faculty, Department of Plastic Reconstructive and Aesthetic Surgery, 25240 Erzurum, Turkey
    Int J Pediatr Otorhinolaryngol 69:1441-4. 2005
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon, fast-growing, pigmented neoplasm of neural crest origin; it primarily affects the maxilla of the infants during the first year of life...
  19. ncbi [Unusual tumor in a 3 month-old baby]
    H Belajouza
    Service de stomatologie et chirurgie maxillofaciale, CHU Sahloul, Sousse, Tunisie
    Rev Stomatol Chir Maxillofac 108:243-4. 2007
  20. ncbi Orbital melanotic neuroectodermal tumor of infancy successfully treated with chemotherapy and subtotal excision
    Robert W Hered
    Nemours Children s Clinic Division of Ophthalmology, Jacksonville, FL 32207, USA
    J AAPOS 11:504-5. 2007
    b>Melanotic neuroectodermal tumor of infancy is a rare condition that typically presents within the first 6 months of life. It rarely metastasizes but is locally aggressive...
  21. ncbi Melanotic neuroectodermal tumor of infancy in the skull: case report and review of the literature
    Masato Matsumoto
    Department of Neurosurgery, Fukushima Medical University, Fukushima 960 1295, Japan
    Surg Neurol 63:275-80. 2005
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm that develops during the first year of life and grows rapidly. Early diagnosis and radical surgery are critical for a long-term cure...
  22. ncbi [Radiological quiz of the month: a maxillary mass in an infant]
    C Hafsa
    Service d Imagerie Medicale, CHU Fattouma Bourguiba, 5000 Monastir, Tunisie
    Arch Pediatr 12:52, 67-9. 2005
  23. ncbi Recurrent melanotic neuroectodermal tumour of infancy of the epididymis and testis: a case report
    Saral Desai
    Department of Pathology, Tata Memorial Hospital, Mumbai
    Indian J Pathol Microbiol 48:363-4. 2005
    b>Melanotic neuroectodermal tumor of infancy or melanotic progonoma is an uncommon tumor, presenting in infants. The epididymis and testis are rare sites of occurrence. This tumor can be confused with round cell tumor (RCT)...
  24. ncbi [Epididymal tumor in a six-months-old infant]
    Colette Deminiere
    Laboratoire d anatomie et de cytologie pathologiques, Hôpital Pellegrin CHU, Bordeaux
    Ann Pathol 22:52-5. 2002
    ..Immunohistochemistry staining and electron microscopy led to the diagnosis of mealnotic neuroectodermal tumor, or progonoma. Prognosis of progonoma, a benign tumor, is generally good, but malignant transformation has been reported...
  25. ncbi Melanotic neuroectodermal tumor of infancy in the soft tissues of the arm: fine needle aspiration biopsy and histologic correlation-a case report
    Yusef M Al-Marzooq
    Department of Pathology, King Fahad Hospital Hofuf, Al Hassa, Saudi Arabia
    Diagn Cytopathol 29:352-5. 2003
    A case of melanotic neuroectodermal tumor of infancy (MNTI) presenting as a soft tissue mass in the right arm of a 6-mo female child is discussed...
  26. ncbi Review of pineal anlage tumor with divergent histology
    Stephen Berns
    Department of Pathology, Orlando Regional Healthcare System M D Anderson Cancer Center, Orlando, Fla, USA
    Arch Pathol Lab Med 130:1233-5. 2006
    ..We review the literature on this tumor, including the clinical presentation, gross pathology, histopathology, immunohistochemistry, differential diagnosis, and prognosis...
  27. ncbi [Melanotic neuroectodermal tumor in an infant]
    C Chossegros
    Clinique de stomatologie et de chirurgie maxillofaciale, CHU Timone, Marseille, France
    Arch Pediatr 2:545-7. 1995
    BACKGROUND--Melanotic neuroectodermal tumor is a mostly benign tumor, rare in childhood, essentially located in the head and neck region...
  28. ncbi Regulation by retinoic acid of insulin-degrading enzyme and of a related endoprotease in human neuroblastoma cell lines
    G Melino
    Biochemistry Laboratory, IDI IRCCS, C10 Department of Experimental Medicine, University of Rome, Tor Vergata, Italy
    Cell Growth Differ 7:787-96. 1996
    ..These results provide evidence that complex posttranslational molecular mechanisms participate in the autocrine/paracrine growth control of the IGF-II loop in neuroblastomas involving proteolytic systems...
  29. ncbi Melanotic neuroectodermal tumor of infancy in the femur: a case report and review of the literature
    Ic Sun Choi
    Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea
    J Pediatr Hematol Oncol 29:854-7. 2007
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon neoplasm that most often affects the maxilla in the first year of life...
  30. ncbi Melanotic neuroectodermal tumour of infancy: a case report
    N Kalra
    Department of Dental Surgery, UCMS and GTB Hospital, Delhi
    J Indian Soc Pedod Prev Dent 19:134-6. 2001
    ....
  31. doi Rapidly growing lesions involving the maxilla in infants: a two-case presentation and deferential diagnosis
    Reza Tabrizi
    Shiraz University of Medical Science, Shiraz, Iran
    J Craniofac Surg 24:e434-8. 2013
    ..Two of these uncommon lesions are melanotic neuroectodermal tumor of infancy (MNTI) and myofibroma...
  32. ncbi Melanotic neuroectodermal tumor of infancy (MNTI) in the epididymis. A case report with immunohistological studies and special consideration of malignant features
    C Jurincic Winkler
    Department of Urology, General Hospital Celle, Germany
    Zentralbl Pathol 140:181-5. 1994
    ..The small tumor cells were only slightly positive for GFAP, NKI-C3, NSE, and S100 but they were negative for cytokeratin and vimentin. Neurofilament and chromogranin could not be proved in the tumor...
  33. ncbi Melanotic neuroectodermal tumor of infancy: case report and review of the literature
    O Camuzard
    CHU Lenval, Service d ORL Pédiatrique des Hôpitaux Pédiatriques de Nice, 57 avenue de la Californie, 06200 Nice, France
    Rev Laryngol Otol Rhinol (Bord) 132:173-6. 2011
    b>Melanotic Neuroectodermal Tumor of Infancy (MNTI) is a rare but distinct neoplastic entity in infancy. Diagnosis is usually made before the age of 12 months...
  34. ncbi Neurocutaneous melanosis presenting as an intradural mass of the cervical canal: magnetic resonance features and the presence of melanin as a clue to diagnosis: case report
    L B Poe
    State University of New York, Health Science Center, Syracuse
    Neurosurgery 35:741-3. 1994
    ..An imaging clue to the diagnosis was apparent as T1-weighted shortening on magnetic resonance in the pia and/or cortex of the cerebellar folia, suggesting the presence of melanin...
  35. doi Melanotic neuroectodermal tumor of infancy: report of one calvarial lesion with T1 shortening and one maxillary lesion
    Korgun Koral
    Department of Radiology, UT Southwestern Medical Center and Children s Medical Center, Dallas, TX 75235, USA
    Clin Imaging 34:382-4. 2010
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor which commonly involves the mandible, maxilla and calvarium. We report two infants with this rare tumor...
  36. ncbi Melanotic neuroectodermal tumor of infancy of the femur
    Murat Elli
    Ondokuz Mayis University, Medical Faculty, Department of Pediatric Oncology, Samsun, Turkey
    Pediatr Hematol Oncol 23:579-86. 2006
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm that often occurs during the first year of life. More than 90% of MNTIs occur in the head and neck region, with most on the anterior part of the maxillary ridge...
  37. ncbi Melanotic neuroectodermal tumour of infancy arising in the maxilla
    A El Saggan
    Department of Otolaryngology Head and Neck Surgery, Haukeland University Hospital, Bergen, Norway
    J Laryngol Otol 112:61-4. 1998
    ..The genital organs are the most frequent extracranial site. We present two cases of melanotic neuroectodermal tumour of infancy arising in the maxilla...
  38. ncbi Long-term results after mandibular continuity resection in infancy: the role of autogenous rib grafts for mandibular restoration
    Andre Eckardt
    Department of Oral and Maxillofacial Surgery, Hannover Medical University, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Craniofac Surg 17:255-60. 2006
    ..Histologic diagnoses were melanotic neuroectodermal tumor, hemangioendothelioma of the mandible, and ameloblastoma...
  39. ncbi Melanotic neuroectodermal tumour of infancy in the maxilla: a case report
    H H Liu
    National Yang Ming University, School of Dentistry, Taipei, Taiwan
    Int J Paediatr Dent 14:371-5. 2004
    ..There have only been a limited number of reports on the dental rehabilitation of postoperative MNTI. We report a case of maxillary MNTI in which the need for dental rehabilitation was emphasized...
  40. ncbi Melanotic neuroectodermal tumor of infancy: case report
    Apio Claudio Martins Antunes
    Department of Neurosurgery, Porto Alegre School of Medicine, Federal University of Rio Grande do Sul, Brazil
    Arq Neuropsiquiatr 63:670-2. 2005
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor, locally aggressive, usually originated from maxilla and mandible and rarely from the skull...
  41. ncbi Melanotic neuroectodermal tumor of the epididymis in infancy: case report and review of the literature
    F Calabrese
    Institutes of Pathology, University of Padova Medical School, Italy
    Urology 46:415-8. 1995
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, benign tumor that usually involves the upper or lower jaw, but it may also arise in other sites. We describe a case of MNTI located in the left epididymis of a 6-month-old boy...
  42. doi Melanotic neuroectodermal tumor of infancy in an African-indigenous patient from the Amazon: a case report
    Thiago Pastor da Silva Pinheiro
    Oral Radiology Department, Dentistry posgraduation program, Federal University of Para, Belem, PA, Brazil
    Head Face Med 9:35. 2013
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare condition that occurs normally in the anterior maxilla of infants aged <1 year...
  43. ncbi Benign melanocytic tumor in infancy: discussion on a rare case and review of the literature
    H H Oruckaptan
    Department of Neurosurgery, Oncology Division, Hacettepe University, School of Medicine, Ankara, Turkey
    Pediatr Neurosurg 32:240-7. 2000
    ..The prognostic criteria, differential diagnosis and its embryological aspects are discussed with an extensive review of the related existing literature...
  44. doi Large cell medulloblastoma with myogenic and melanotic differentiation: a case report with molecular analysis
    Alexandros D Polydorides
    Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY, USA
    J Neurooncol 88:193-7. 2008
    ..diverse tumor represents a pattern of medulloblastoma with striated muscle and pigmented epithelial differentiation, rather than a teratoma or a cerebellar variant of melanotic neuroectodermal tumor of infancy ('progonoma').
  45. ncbi A novel PNET cell line with melanotic differentiation
    S Moriuchi
    Department of Neurosurgery, Center for Adult Diseases, Osaka, Japan
    Anticancer Res 16:779-84. 1996
    The primitive neuroectodermal tumor (PNET) cell line, ONS-99, was established from a human melanotic neuroectodermal tumor of infancy (MNTI). ONS-99 cells were polygonal adherent cells and transplantable to BALB/c-nu/nu mouse...
  46. ncbi Establishment and characterization of a human neuroectodermal cell line (TB) from a cerebrospinal fluid specimen
    G Sorrentino
    Institute of Neurological Sciences, Faculty of Medicine, 2nd University of Naples, Via S Pansini 5, 80131, Naples, Italy
    Brain Res 827:205-9. 1999
    ..In summary, TB cells represent primitive neuroectodermal cells having the potential for neuronal, myoblastic and possibly melanoblastic differentiation...
  47. ncbi [Melanotic progonoma. Apropos of a voluminous tumor in an infant]
    N J Dilu
    Service de Stomatologie et de Chirurgie Maxillo Faciale, Cliniques Universitaires de Kinshasa,
    Rev Stomatol Chir Maxillofac 99:103-5. 1998
    ..The large size of the tumor can hinder feeding in infants. Surgical cure is generally easy and outcome quite satisfactory without recurrence...
  48. pmc Melanotic neuroectodermal tumor of infancy: Report of a case associated with high urinary excretion of Vanilmandelic acid
    P N Tandon
    Department of Oral and Maxillofacial Surgery, Teerthanker Mahaveer Dental College and Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India
    Contemp Clin Dent 2:337-41. 2011
    b>Melanotic neuroectodermal tumor of infancy is a rare congenital neoplasm involving the head and neck region in young patients. A case of melanotic neuroectodermal tumor of infancy is presented...
  49. doi Melanotic neuroectodermal tumor of infancy disseminated by a ventriculoperitoneal shunt and diagnosed from the inguinal sac
    In Hyuk Yoo
    Departments of Pediatrics General Surgery, College of Medicine, The Catholic University of Korea, Seoul St Mary s Hospital, Seocho gu Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Pediatr Hematol Oncol 36:e61-4. 2014
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare congenital neoplasm that originates from the neural crest cells, which give rise to the melanocytes of the skin and leptomeninges...
  50. ncbi Melanotic neuroectodermal tumor of infancy: clinical, radiological, and pathological features
    D J Fowler
    Department of Pediatric Histopathology, Great Ormond Street Hospital, London, UK
    Fetal Pediatr Pathol 25:59-72. 2006
    We present a case of a 4-month-old female infant with a maxillary melanotic neuroectodermal tumor of infancy (MNTI) and review the pooled data from previous publications on this entity...
  51. ncbi Melanotic neuroectodermal tumor of infancy: report of a case with myogenic differentiation
    Dale A Ellison
    Department of Pathology, Arkansas Children s Hospital and University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Pediatr Dev Pathol 10:157-60. 2007
    ..The mass was excised, and the histopathologic features were diagnostic for melanotic neuroectodermal tumor of infancy...
  52. ncbi Slow-growing lambdoid melanotic neuroectodermal tumor of infancy
    Federico Di Rocco
    Department of Pediatric Neurosurgery, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    Eur J Pediatr 166:739-41. 2007
    ..To illustrate this latter presentation, we present a case of a slowly growing melanotic neuroectodermal tumor of infancy located on the right lambdoid suture.
  53. ncbi A 4-year-old girl with mass in the frontotemporal bone
    Shanop Shuangshoti
    Brain Pathol 16:333-4. 2006
  54. ncbi Melanocytic neuroectodermal tumor of infancy: excision and primary palatal repair at 7 months of age
    Kerry Latham
    Division of Plastic Surgery, Miami Children s Hospital, Miami, FL 33136, USA
    J Craniofac Surg 18:450-4. 2007
    ..A 7-month-old boy was found in a Haitian orphanage with a growing, very large mass originating from his right maxilla...
  55. ncbi Rapidly growing intraoral swelling involving the maxilla of an infant
    Taylor P McGuire
    Division of Oral and Maxillofacial Surgery, University of Toronto, Toronto, Ontario, Canada
    J Oral Maxillofac Surg 65:1595-9. 2007
  56. doi Urgent maxillectomy in infants for rare infantile maxillary tumors
    Hazem E Amer
    Department of Otolaryngology, Mansoura Faculty of Medicine, Gomhoria Street, Mansoura 35516, Egypt
    Int J Pediatr Otorhinolaryngol 75:1071-4. 2011
    The purpose of this study was to present our experience with definitive surgical management of infants with Melanotic neuroectodermal tumor of infant (MNTI) and epithelioid hemangioendothelioma (EHE).
  57. pmc Melanotic neuroectodermal tumor of infancy: Presentation of a case affecting the maxilla
    Pooja Agarwal
    Department of Oral Pathology and Microbiology, Subharti Dental College, Meerut, U P, India
    J Oral Maxillofac Pathol 14:29-32. 2010
    b>Melanotic neuroectodermal tumor of infancy is a rare, distinctive neoplasm of early infancy with rapid expansile growth and a high rate of recurrence. Most commonly, the lesion affects the maxilla of infants during the first year of life...
  58. doi Pineal anlage tumor in a 5-month-old boy
    Joffre E Olaya
    Department of Neurosurgery, Loma Linda University Medical Center, Loma Linda, California 92354, USA
    J Neurosurg Pediatr 5:636-40. 2010
    ....
  59. doi Mandibular melanotic neuroectodermal tumor of infancy treated conservatively with enucleation
    Evangelia P Piperi
    Department of Oral Medicine and Pathology, Dental School, National and Kapodistrian University of Athens, Athens, Greece
    J Craniofac Surg 21:685-8. 2010
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon, rapidly growing neoplasm of neural crest origin that primarily develops in the maxilla of infants during their first year of life...
  60. doi Melanotic neuroectodermal tumor of the brain recurring 12 years after complete remission: case report
    Shunsuke Omodaka
    Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai, Miyagi 980 8574, Japan
    Brain Tumor Pathol 27:51-7. 2010
    We describe a rare case of melanotic neuroectodermal tumor (MNT) of the brain recurring 12 years after complete remission. An 11-year-old girl initially presented with exotropia and bilateral papilledema...
  61. ncbi [Oral and perioral endogenous pigmented lesions]
    Cristina Popa
    Catedra de Chirurgie Orală si Maxilo Facială, Facultatea de Medicina Dentara, Universitatea de Medicină si Farmacie Gr T Popa Iaşi
    Rev Med Chir Soc Med Nat Iasi 112:1054-60. 2008
    ..In this article, pigmented lesions are described to allow practitioner to elaborate a positive diagnosis of endogenous pigmented lesions and to facilitate an early detection of these lesions particularly the malignant ones...
  62. doi Melanotic neuroectodermal tumor of infancy presenting in the subcutaneous soft tissue of the thigh
    Shanon R Lacy
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Dermatopathol 32:282-6. 2010
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare and diagnostically challenging neoplasm typically presenting in the bones of the maxilla, skull, or mandible...
  63. doi Melanotic neuroectodermal tumor of infancy (MNT1) arising in the skull. Short review of two cases
    Vassilis Lambropoulos
    Department of Pediatric Surgery, Aristotle University, G H Papageorgiou, Ring Road N Efkarpia, Thessaloniki, Greece
    Acta Neurochir (Wien) 152:869-75. 2010
    b>Melanotic neuroectodermal tumor of infancy (MNT1) is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, and rapidly growing that develops during the first year of life...
  64. doi Jaw and gum tumours in children
    Hemonta Kumar Dutta
    Department of Pediatric Surgery, Assam Medical College, Dibrugarh 786002, Assam, India
    Pediatr Surg Int 25:781-4. 2009
    ..Children presenting with jaw tumours during 2001 till 2007 are presented. Their modes of presentation, operative procedures and findings, histology and post operative results have been described...
  65. doi Early outcome of three cases of melanotic neuroectodermal tumour of infancy
    F M A Butt
    Department of Oral and Maxillofacial Surgery, University of Nairobi, Kenya
    J Craniomaxillofac Surg 37:434-7. 2009
    ..The literature shows that radiotherapy and chemotherapy may be indicated especially in cases where total surgical extirpation is equivocal. This article contributes three more cases of MNTI surgically managed at our institution...
  66. doi Melanotic progonoma of the skull in infancy
    Mehmet Kantar
    Pediatric Oncology Unit, Department of Pediatrics, Ege University School of Medicine, 35100, Izmir, Turkey
    Childs Nerv Syst 24:1371-5. 2008
    Melanotic progonoma or melanotic neuroectodermal tumor is a rare tumor in infancy. This lesion has to be considered in the differential diagnosis of benign or malignant lesions of calvarium.
  67. doi Recurrent melanotic neuroectodermal tumor in the orbit successfully treated with resection followed by pediculated periosteal flaps
    Kyoichi Nakanishi
    Department of Pediatric and Developmental Science, Mie University Graduate School of Medicine, Tsu, Japan
    Pediatr Blood Cancer 51:430-2. 2008
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor arising mainly in the orofacial bones. Among more than 200 cases described in articles, only seven cases involved orbital regions...
  68. ncbi [Diagnosis and management of oral melanotic nenroectodermal tumor of infancy]
    Yan Chen
    Department of Oral Pathology, Peking University School and Hospital of Stomatology, Beijing 100081, China
    Beijing Da Xue Xue Bao 40:19-23. 2008
    To investigate the clinicopathological features of oral melanotic neuroectodermal tumor of infancy (MNTI).
  69. ncbi Melanotic neuroectodermal tumour of infancy: a case report
    N Retna Kumari
    Department of Pedodontics, Government Dental College, Trivandrum 695 011, India
    J Indian Soc Pedod Prev Dent 25:148-51. 2007
    A case of melanotic neuroectodermal tumor of infancy occurring in the maxilla in a 13 day old neonate is described...
  70. ncbi Melanotic neuroectodermal tumor of infancy in the skull: CT and MRI features
    C Suzuki
    J Neuroradiol 34:212-3. 2007
  71. ncbi Diagnostic cytologic features of an epididymal melanotic neuroectodermal tumor of infancy present in scrotal fluid: a case report
    Liron Pantanowitz
    Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts 01199, USA
    Acta Cytol 50:460-5. 2006
    The cytologic features of melanotic neuroectodermal tumor of infancy (MNTI) have been described in rare cases only, and these reports have been based solely on direct smears obtained from aspirated tumor material or from touch ..
  72. ncbi March 2000: 5 month old boy with occipital bone mass
    J Caird
    Department of Neuropathology, Beaumont Hospital, Dublin, Ireland
    Brain Pathol 10:317-9. 2000
    ..One year after a wide local excision the patient is tumor-free and developing normally. The prognosis for MNETI in general is excellent with no requirement for additional radiotherapy or chemotherapy...
  73. ncbi Malignant melanotic neuroectodermal tumour of infancy affecting the occipital squama
    T Patankar
    Department of Radiology, Seth G S Medical College, Mumbai, India
    J Postgrad Med 44:73-5. 1998
    ..An unusual case of a melanotic neuroectodermal tumour of the occipital squama, which underwent malignant transformation in a nine-month-old infant is reported and pertinent literature reviewed...
  74. ncbi Cytologic diagnosis of a melanotic neuroectodermal tumor of infancy occurring in the cranial bones
    J D Rege
    Department of Pathology, B Y L Nair Ch Hospital and T N Medical College, Mumbai Central, Mumbai, Maharashtra, India
    Diagn Cytopathol 21:280-3. 1999
    ..In the present case, following the cytologic diagnosis a wide local excision was carried out, and the histologic examination confirmed the cytologic diagnosis. Diagn. Cytopathol. 1999;21:280-283...
  75. ncbi Melanotic neuroectodermal tumor of infancy occurring in the left thigh of a 6-month-old female infant
    O Scheck
    Institute of Pathology, Eberhard Karls University, , Federal Republic of Germany
    Ultrastruct Pathol 13:23-33. 1989
    We report an exceptional case of melanotic neuroectodermal tumor of infancy (MNTI) occurring in the soft tissue of the left thigh of a 6-month-old female infant...
  76. ncbi Melanotic neuroectodermal tumour of infancy at the anterior fontanelle
    S Nishio
    Department of Neurosurgery, Neurological Institute, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Neuroradiology 41:202-4. 1999
    ..The tumour was dense on CT, while MRI showed a major part of the tumour to be isointense with cerebral cortex on both T1- and T2-weighted images. The neuroimaging and clinical features are briefly discussed...
  77. ncbi Melanotic progonoma of the brain: a case report and review
    C H Rickert
    Institute of Neuropathology, Westfalische Wilhelms Universitat, Munster, Germany
    Childs Nerv Syst 14:389-93. 1998
    ..We present the case of a 1-year-old boy suffering from a melanotic progonoma of the pineal gland, who died at the age of 22 months with extensive spinal and abdominal metastases 10 months after partial removal of the tumor...
  78. ncbi Pigmented neuroectodermal tumor of infancy in the epididymis. A case report
    T Toda
    Department of Clinical Laboratory Medicine, School of Medicine, University of the Ryukyus, Okinawa, Japan
    Acta Cytol 42:775-80. 1998
    ..CONCLUSION: Cytology has not been applied to the diagnoses of PNTI. In our opinion, fine needle aspiration cytology could be helpful in the preoperative diagnosis of this tumor...
  79. ncbi Melanogenic neuroectodermal tumor of the retina (primary malignant melanoma of the retina)
    S K Freitag
    Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 115:1581-4. 1997
    ..To our knowledge, such an ocular tumor has not been reported previously...
  80. ncbi Three-dimensional reconstruction of melanotic neuroectodermal tumor of infancy involving the occipital bone and dura
    F A Raila
    Department of Radiology, University of Mississippi Medical Center, Jackson 39216 4505, USA
    J Neuroimaging 7:123-6. 1997
    A rare case of melanotic neuroectodermal tumor of infancy involving the right occipital bone in an 11-month-old infant is described. The bone tumor and its dural extension were surgically removed...
  81. ncbi Melanotic neuroectodermal tumour of infancy: an immunohistochemical and ultrastructural study
    Z L Nelson
    Joint Department of Oral Pathology, London Hospital Medical College
    Br J Oral Maxillofac Surg 33:375-80. 1995
    ..Both cases have responded to local excision, with no recurrence more than a year after initial treatment...
  82. ncbi Melanotic neuroectodermal tumor of infancy: report of a case
    R S Gomez
    Department of Oral Surgery and Oral Pathology, School of Dentistry, University of Minas Gerais, Belo Horizonte, Brazil
    J Clin Pediatr Dent 20:253-5. 1996
    The melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon benign neoplasm frequently detected in young infants, which has a predilection for the head and neck region, particularly maxilla...
  83. ncbi Melanotic neuro-ectodermal tumour of infancy arising from the squamous and occipital bone
    A Kacker
    Department of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi
    J Laryngol Otol 107:843-4. 1993
    ..This lesion shows a good response to conservative surgical excision with few recurrences but it should be followed up for long periods of time because of the rare malignant change possible in the tumour...
  84. ncbi Melanotic neuroectodermal tumor of the epididymis. A case report
    A Kanungo
    Department of Pathology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India
    Indian J Cancer 31:138-40. 1994
    ..Melanotic neuroectodermal tumors occur very rarely in the epididymis, only eleven cases having been reported to date in the world literature. An additional case is reported which we believe is the first from India...
  85. ncbi Melanotic neuroectodermal tumor of infancy: a molecular approach to diagnosis. Case report
    T Nitta
    Department of Neurosurgery, Juntendo University School of Medicine, Tokyo, Japan
    J Neurosurg 83:145-8. 1995
    A case of melanotic neuroectodermal tumor of infancy arising from the transverse sinus is presented. The tumor was located on the outer surface of the dura and extended extracranially through the occipitomastoid suture...
  86. ncbi Usefulness of electron microscopy in the diagnosis of "small" round cell tumors of the sinonasal region
    K W Min
    Department of Pathology, University of Oklahoma Health Science Center, Oklahoma City 73190, USA
    Ultrastruct Pathol 19:347-63. 1995
    ..in 27 cases: esthesioneuroblastoma (EN), 12; undifferentiated carcinoma, 6; melanoma, 3; lymphoma, 3; melanotic neuroectodermal tumor, 1; rhabdomyosarcoma, 1; and pituitary adenoma, 1...
  87. ncbi [Melanotic neuroectodermal tumor of infancy]
    J Rustemeyer
    , Kiefer und Gesichtschirurgie, , Bremen
    Klin Padiatr 213:69-73. 2001
    BACKGROUND: The melanotic neuroectodermal tumor of infancy is a rare and so far as being classified neoplasm with a high rate of recurrence for one year after diagnosis...
  88. ncbi Melanotic neuroectodermal tumour of the pineal region
    C Gorhan
    Department of Neuroradiology, , CHRU Lille, France
    Neuroradiology 43:944-7. 2001
    ..The pathological diagnosis was made on the resected piece. Embryology of the pineal gland and the histology of melanotic neuroectodermal tumour of infancy are discussed...
  89. ncbi Melanotic neuroectodermal tumor of infancy
    Brenda L Nelson
    National Naval Medical Center, Bethesda, MD, USA
    Ear Nose Throat J 85:365. 2006
  90. ncbi Melanotic neuroectodermal tumor of infancy discovered after head trauma
    Paisit Paueksakon
    Department of Pathology, Vanderbilt University Medical Center, Nashville, Tenn 37232, USA
    Pediatr Neurosurg 36:33-6. 2002
    b>Melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm that generally arises in the maxilla during the first year of life. Involvement of bones of the cranial vault or brain is extremely rare...
  91. ncbi Melanotic medulloblastoma of cerebellum: a case report
    P Karkuzhali
    Department of Neuropathology, Institute of Neurology, Madras Medical College, Chennai 3
    Indian J Pathol Microbiol 48:243-4. 2005
    ..medulloblastoma is a variant of medulloblastoma, which shares some of the histological features of Melanotic neuroectodermal tumor of infancy...
  92. ncbi Effectiveness of chemotherapy in melanotic neurectodermal tumor of infancy
    T Priya Kumari
    Division of Paediatric Oncology, Department of Imageology, Regional Cancer Centre, Thriuvananthapuram 695 011, Kerala State, India
    Pediatr Hematol Oncol 22:199-206. 2005
    ..All 3 infants showed good response to chemotherapy. In 2 of them complete residual tumor resection became possible; 2 of them are alive and tumor regression continues. One child had local recurrence later and was lost for follow-up...
  93. ncbi [Autologous rib graft for restoration of continuity defects of the mandible]
    A Eckardt
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Medizinische Hochschule Hannover, 30625 Hannover
    Mund Kiefer Gesichtschir 9:66-70. 2005
    ....
  94. ncbi Cytomorphological variation in two cases of melanotic neuroectodermal tumor of infancy
    Nalini Gupta
    Diagn Cytopathol 32:58-60. 2005
  95. ncbi Management of melanotic neuroectodermal tumor of infancy
    Márcia Gaiger de Oliveira
    School of Dentistry, Oral Pathology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Ann Diagn Pathol 8:207-12. 2004
    b>Melanotic neuroectodermal tumor of infancy is a rare congenital neoplasm involving the head and neck in young patients...
  96. ncbi Melanotic neuroectodermal tumor of infancy (MNTI)
    Sheila J Adad
    Diagn Cytopathol 30:67-9. 2004
  97. ncbi Melanotic neuroectodermal tumour of infancy arising in skull
    N Haider
    Med Pediatr Oncol 41:495-6. 2003
  98. pmc Biological functions of the ISWI chromatin remodeling complex NURF
    Paul Badenhorst
    Laboratory of Molecular Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda Maryland 20892 4255, USA
    Genes Dev 16:3186-98. 2002
    ..Finally, mutants in NURF subunits exhibit neoplastic transformation of larval blood cells that causes melanotic tumors to form...
  99. ncbi Melanotic neuroectodermal tumour in an infant
    Anju Gupta
    Division of Pediatric Hematology Oncology, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Indian J Pediatr 69:725-6. 2002
    ..The encounter with an unusual melanotic neuroectodermal tumour of the jaw in a young infant is described in this report. There has been no recurrence, after complete surgical excision, in a follow-up period of six months...
  100. ncbi Recurrent melanotic neuroectodermal tumor of infancy
    Wayne T Shaia
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0709, USA
    Am J Otolaryngol 23:249-52. 2002
  101. ncbi [Melanotic progonoma]
    V Tantcheu
    Service de Radiologie, Hospital d Enfants Armand Trousseau, 75571 Paris Cedex, France
    J Radiol 83:63-5. 2002