skull base neoplasms

Summary

Summary: Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS).

Top Publications

  1. ncbi Jugular foramen tumors: diagnosis and treatment
    Ricardo Ramina
    Neurosurgery Department of Instituto de Neurologia de Curitiba, Brazil
    Neurosurg Focus 17:E5. 2004
  2. ncbi Chordoma
    Paolo G Casali
    Adult Sarcoma Medical Oncology Unit, Istituto Nazionale dei Tumori, Milano, Italy
    Curr Opin Oncol 19:367-70. 2007
  3. ncbi Surgical removal of small petroclival meningiomas
    R Ramina
    Department of Neurosurgery, Neurological Institute of Curitiba, Curitiba, Brazil
    Acta Neurochir (Wien) 150:431-8; discussion 438-9. 2008
  4. ncbi Proton radiation therapy for chordomas and chondrosarcomas of the skull base
    E B Hug
    Department of Radiation Medicine, Loma Linda University Medical Center, California 92354, USA
    J Neurosurg 91:432-9. 1999
  5. ncbi Current comprehensive management of cranial base chordomas: 10-year meta-analysis of observational studies
    Salvatore Di Maio
    Department of Neurological Surgery, University of Washington, Harborview Medical Center, Seattle, Washington 98104, USA
    J Neurosurg 115:1094-105. 2011
  6. ncbi Gamma knife surgery for skull base meningiomas
    Robert M Starke
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 116:588-97. 2012
  7. pmc Fractionated stereotactic radiotherapy for skull base tumors: analysis of treatment accuracy using a stereotactic mask fixation system
    Giuseppe Minniti
    Department of Radiation Oncology, Sant Andrea Hospital, University La Sapienza, Via di Grottarossa 1035 1039, 00189, Rome, Italy
    Radiat Oncol 5:1. 2010
  8. ncbi The relevance of Simpson Grade I and II resection in modern neurosurgical treatment of World Health Organization Grade I meningiomas
    Michael E Sughrue
    Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    J Neurosurg 113:1029-35. 2010
  9. ncbi Visual field preservation after multisession cyberknife radiosurgery for perioptic lesions
    John R Adler
    Department of Neurosurgery, Stanford University Medical School, Stanford, California, USA
    Neurosurgery 59:244-54; discussion 244-54. 2006
  10. ncbi Therapy strategies for locally advanced adenoid cystic carcinomas using modern radiation therapy techniques
    Daniela Schulz-Ertner
    Department of Radiation Oncology, University of Heidelberg, Heidelberg, Germany
    Cancer 104:338-44. 2005

Research Grants

Detail Information

Publications237 found, 100 shown here

  1. ncbi Jugular foramen tumors: diagnosis and treatment
    Ricardo Ramina
    Neurosurgery Department of Instituto de Neurologia de Curitiba, Brazil
    Neurosurg Focus 17:E5. 2004
    ..The purpose of this study was to evaluate a series of patients with jugular foramen tumors who were surgically treated in the past 16 years, and to analyze the surgical technique, complications, and outcomes...
  2. ncbi Chordoma
    Paolo G Casali
    Adult Sarcoma Medical Oncology Unit, Istituto Nazionale dei Tumori, Milano, Italy
    Curr Opin Oncol 19:367-70. 2007
    ..To review developments in chordoma treatment...
  3. ncbi Surgical removal of small petroclival meningiomas
    R Ramina
    Department of Neurosurgery, Neurological Institute of Curitiba, Curitiba, Brazil
    Acta Neurochir (Wien) 150:431-8; discussion 438-9. 2008
    ..8 cm) treated with radical surgical removal. Total resection (Simpson's Grade 1) [43] was possible with minimal morbidity and no mortality...
  4. ncbi Proton radiation therapy for chordomas and chondrosarcomas of the skull base
    E B Hug
    Department of Radiation Medicine, Loma Linda University Medical Center, California 92354, USA
    J Neurosurg 91:432-9. 1999
    ....
  5. ncbi Current comprehensive management of cranial base chordomas: 10-year meta-analysis of observational studies
    Salvatore Di Maio
    Department of Neurological Surgery, University of Washington, Harborview Medical Center, Seattle, Washington 98104, USA
    J Neurosurg 115:1094-105. 2011
    ..This meta-analysis measures the relationship of complete resection and type of adjuvant radiation therapy to 5-year progression-free survival (PFS) and overall survival (OS) of cranial base chordomas...
  6. ncbi Gamma knife surgery for skull base meningiomas
    Robert M Starke
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 116:588-97. 2012
    ..In this study, the authors evaluate the outcomes of skull base meningiomas treated with Gamma Knife surgery (GKS) both as an adjunct to microsurgery and as a primary treatment modality...
  7. pmc Fractionated stereotactic radiotherapy for skull base tumors: analysis of treatment accuracy using a stereotactic mask fixation system
    Giuseppe Minniti
    Department of Radiation Oncology, Sant Andrea Hospital, University La Sapienza, Via di Grottarossa 1035 1039, 00189, Rome, Italy
    Radiat Oncol 5:1. 2010
    ..To assess the accuracy of fractionated stereotactic radiotherapy (FSRT) using a stereotactic mask fixation system...
  8. ncbi The relevance of Simpson Grade I and II resection in modern neurosurgical treatment of World Health Organization Grade I meningiomas
    Michael E Sughrue
    Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    J Neurosurg 113:1029-35. 2010
    ....
  9. ncbi Visual field preservation after multisession cyberknife radiosurgery for perioptic lesions
    John R Adler
    Department of Neurosurgery, Stanford University Medical School, Stanford, California, USA
    Neurosurgery 59:244-54; discussion 244-54. 2006
    ..The current retrospective study is intended to help address these shortcomings...
  10. ncbi Therapy strategies for locally advanced adenoid cystic carcinomas using modern radiation therapy techniques
    Daniela Schulz-Ertner
    Department of Radiation Oncology, University of Heidelberg, Heidelberg, Germany
    Cancer 104:338-44. 2005
    ....
  11. ncbi Prognostic factors for long-term outcome of patients with surgical resection of skull base chordomas-106 cases review in one institution
    Zhen Wu
    Skull Base and Brainstem Tumor Division, Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Tiantan Xili 6, Beijing, 100050, China
    Neurosurg Rev 33:451-6. 2010
    ....
  12. ncbi Clinical management of petroclival meningiomas and the eternal quest for preservation of quality of life: personal experiences over a period of 20 years
    Volker Seifert
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 152:1099-116. 2010
    ..Surgical concepts and the operative decision-making process are demonstrated in four illustrative cases...
  13. ncbi Proton therapy in chordoma of the base of the skull: a systematic review
    Maurizio Amichetti
    ATreP Provincial Agency for Proton Therapy, Via F lli Perini, 181, 38100 Trento, Italy
    Neurosurg Rev 32:403-16. 2009
    ....
  14. ncbi Visual outcome of tuberculum sellae meningiomas after extradural optic nerve decompression
    Tiit Mathiesen
    Department of Neurosurgery, Karolinska Hospital, Stockholm, Sweden
    Neurosurgery 59:570-6; discussion 570-6. 2006
    ....
  15. ncbi Surgical management of tuberculum sellae meningioma: role of selective extradural anterior clinoidectomy
    Naoki Otani
    Department of Neurosurgery, University Hospital of Zurich, Zurich, Switzerland
    Br J Neurosurg 20:129-38. 2006
    ....
  16. ncbi Effects of using combined transpetrosal surgical approaches to treat petroclival meningiomas
    Tiit Mathiesen
    Neurosurgery Section, Institute of Clinical Neuroscience, Karolinska University Hospital, Solna, Stockholm, Sweden
    Neurosurgery 60:982-91; discussion 991-2. 2007
    ....
  17. ncbi A comparative review of multidetector CT angiography and MRI in the diagnosis of jugular foramen lesions
    A Christie
    Radiology Department, Institute of Neurosciences, Glasgow, Scotland, UK
    Clin Radiol 65:213-7. 2010
    ..To compare the efficiency of multidetector computed tomography (MDCT) and magnetic resonance imaging (MRI) in the diagnosis of jugular foramen lesions...
  18. ncbi The natural history of untreated skull base meningiomas
    Rajesh Bindal
    Department of Neurosurgery, Neuroophthalmology and Neuroradiology Clarian Health Methodist Hospital, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Surg Neurol 59:87-92; discussion 92. 2003
    ..Although there are reports on the natural history of meningiomas, most series contain only a few cases of meningiomas involving the skull base. Natural history information is important when recommending treatment and evaluating results...
  19. ncbi Neuropsychological outcome after fractionated stereotactic radiotherapy (FSRT) for base of skull meningiomas: a prospective 1-year follow-up
    Sarah Steinvorth
    Department of Neurology, University of Heidelberg, Germany
    Radiother Oncol 69:177-82. 2003
    ..The purpose of this study was to evaluate the cognitive outcome after fractionated stereotactic radiotherapy (FSRT) in patients with base of skull meningiomas...
  20. ncbi Stereotactic radiation treatment of vestibular schwannoma: indications, limitations, and outcomes
    George S Conley
    Department of Otolaryngology, Eye and Ear Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Curr Opin Otolaryngol Head Neck Surg 18:351-6. 2010
    ..The recent literature regarding the indications, limitations, and outcomes for stereotactic radiation treatment is reviewed...
  21. ncbi Temporal lobe reactions after radiotherapy with carbon ions: incidence and estimation of the relative biological effectiveness by the local effect model
    Ingmar Schlampp
    Department of Radiation Oncology, University of Heidelberg, Germany
    Int J Radiat Oncol Biol Phys 80:815-23. 2011
    ....
  22. ncbi Gamma Knife surgery of meningiomas located in the posterior fossa: factors predictive of outcome and remission
    Robert M Starke
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 114:1399-409. 2011
    ..In this study, the authors evaluate the outcomes of posterior fossa meningiomas treated with Gamma Knife surgery (GKS). The authors also assess factors predictive of new postoperative neurological deficits and tumor progression...
  23. ncbi Jugular foramen tumors: clinical characteristics and treatment outcomes
    Jose N Fayad
    House Ear Institute and House Ear Clinic, Los Angeles, California 90057, USA
    Otol Neurotol 31:299-305. 2010
    ..To describe the diagnosis, management, and treatment outcome of jugular foramen (JF) tumors...
  24. ncbi Endoscopic endonasal versus open transcranial resection of anterior midline skull base meningiomas
    Ricardo J Komotar
    Department of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    World Neurosurg 77:713-24. 2012
    ....
  25. ncbi The combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumors
    James K Liu
    Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Neurosurgery 59:ONS115-25; discussion ONS115-25. 2006
    ..The details of this approach are described and illustrated in a stepwise fashion, and the microsurgical anatomy is reviewed...
  26. ncbi Long-term control of clival chordoma with initial aggressive surgical resection and gamma knife radiosurgery for recurrence
    Eiji Ito
    Department of Neurosurgery, Fukushima Medical University, 1 Hikarigaoka, Fukushima 960 1295, Japan
    Acta Neurochir (Wien) 152:57-67; discussion 67. 2010
    ..This study analyzed long-term outcomes for clival chordomas after initial aggressive surgical resection and gamma knife radiosurgery for recurrence and investigated clinical factors predicting recurrence...
  27. ncbi Radiation-induced osteosarcomas of the calvarium and skull base
    Akash J Patel
    Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA
    Cancer 117:2120-6. 2011
    ..To date, publications on radiation-induced osteosarcoma of the cranium are limited to a few small series and case reports...
  28. ncbi Comparison of MR imaging and CT in discriminating tumor infiltration of bone and bone marrow in the skull base
    N Tomura
    Department of Radiology, Akita University School of Medicine, Akita City, Japan
    Comput Med Imaging Graph 22:41-51. 1998
    ..5% of tumors involving the posterior compartment, respectively. Precontrast T1-weighted images were more accurate than other pulse sequences in revealing bone and bone marrow that were replaced by tumors...
  29. ncbi World Health Organization Grades II and III meningiomas are rare in the cranial base and spine
    Burak Sade
    Brain Tumor Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Neurosurgery 61:1194-8; discussion 1198. 2007
    ..This study was undertaken to assess a possible relationship between the tumor location and the incidence of World Health Organization (WHO) Grades II and III meningiomas...
  30. ncbi Skull base: pseudolesion or true lesion?
    Ilona M Schmalfuss
    North Florida South Georgia Veterans Administration, Gainesville, FL, USA
    Eur Radiol 18:1232-43. 2008
    ....
  31. ncbi A Comparison of clinical target volumes determined by CT and MRI for the radiotherapy planning of base of skull meningiomas
    V S Khoo
    Neuro oncology Unit and the Academic Unit of Radiotherapy and Oncology, The Institute of Cancer Research and The Royal Marsden NHS Trust, Sutton, Surrey, UK
    Int J Radiat Oncol Biol Phys 46:1309-17. 2000
    ..To assess the utility of image registration and to compare the localization of clinical target volumes (CTV) using CT and MRI for patients with base of skull meningiomas undergoing radiotherapy...
  32. ncbi Gamma knife radiosurgery for benign tumors with symptoms from brainstem compression
    Kotaro Nakaya
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 77:988-95. 2010
    ..This study evaluated the role of radiosurgery in the management of symptomatic patients with brainstem compression from benign basal tumors...
  33. ncbi High precision focused irradiation in the form of fractionated stereotactic conformal radiotherapy (SCRT) for benign meningiomas predominantly in the skull base location
    R Jalali
    Neuro Oncology Unit, The Institute of Cancer Research, The Royal Marsden NHS Trust, London, UK
    Clin Oncol (R Coll Radiol) 14:103-9. 2002
    ..To present early clinical results of stereotactic conformal radiotherapy (SCRT) in patients with benign predominantly skull base meningiomas...
  34. ncbi Sarcoma of the sella after radiotherapy for pituitary adenoma
    Sven Berkmann
    Department of Neurosurgery, Kantonsspital Aarau, Switzerland
    Acta Neurochir (Wien) 152:1725-35. 2010
    ..Additionally, one must include these tumors into the differential diagnosis in pituitary patients presenting with tumor recurrence more than 5 years after radiotherapy in combination with a secondary lack of hormonal activity...
  35. pmc Fractionated stereotactic conformal radiotherapy for large benign skull base meningiomas
    Giuseppe Minniti
    Department of Radiation Oncology, Sant Andrea Hospital, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Radiat Oncol 6:36. 2011
    ..To assess the safety and efficacy of fractionated stereotactic radiotherapy (FSRT) for large skull base meningiomas...
  36. ncbi Radiology of skull base neoplasms
    D D Durden
    Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA
    Otolaryngol Clin North Am 34:1043-64, vii. 2001
    Computed tomography (CT) and magnetic resonance (MR) imaging are used routinely to stage skull base neoplasms preoperatively, define the extent of the tumor, identify perineural spread, plan surgery and radiation therapy, and evaluate the ..
  37. pmc Surgical management of tuberculum sellae meningiomas: involvement of the optic canal and visual outcome
    U Schick
    Clinic of Neurological Surgery, Wedau Kliniken, Zu den Rehwiesen 9, 47055 Duisburg, Germany
    J Neurol Neurosurg Psychiatry 76:977-83. 2005
    ..To present a large series of surgically treated tuberculum sellae meningiomas with particular regard to involvement of the optic canal and visual outcome...
  38. ncbi The principles of skull base radiosurgery
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pennsylvania 15213, USA
    Neurosurg Focus 24:E11. 2008
    ..In this report, the authors discuss technical concepts and dose selection in skull base radiosurgery...
  39. ncbi Gamma Knife radiosurgery for skull base meningioma: long-term results of low-dose treatment
    Yoshiyasu Iwai
    Department of Neurosurgery, Osaka City General Hospital, Osaka, Japan
    J Neurosurg 109:804-10. 2008
    ..In this study, the authors evaluate the long-term results after Gamma Knife radiosurgery of cranial base meningiomas. This study is a follow-up to their previously published report on the early results...
  40. ncbi A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base
    Maurizio Amichetti
    ATreP, Agenzia Provinciale per la Protonterapia, Via F lli Perini, 181, 38100 Trento, Italy
    Neurosurg Rev 33:155-65. 2010
    ..The use of PT following maximal surgical resection shows a very high probability of medium- and long-term cure with a relatively low risk of significant complications...
  41. ncbi Intensity-modulated stereotactic radiotherapy vs. stereotactic conformal radiotherapy for the treatment of meningioma located predominantly in the skull base
    Brigitta G Baumert
    Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland
    Int J Radiat Oncol Biol Phys 57:580-92. 2003
    ..This study evaluates a possible advantage of intensity-modulated stereotactic radiotherapy (IMSRT) over stereotactic conformal radiotherapy (SCRT) in the treatment of lesions in the base of the skull...
  42. ncbi Selection of beam angles for radiotherapy of skull base tumours using charged particles
    O Jakel
    Deutsches Krebsforschungszentrum Heidelberg, Division for Medical Physics, Germany
    Phys Med Biol 45:1229-41. 2000
    ..Treatment angle combinations are suggested that should be accessible for any beam line design using either fixed beams or a gantry...
  43. pmc Radiotherapy and radiosurgery for benign skull base meningiomas
    Giuseppe Minniti
    Department of Radiotherapy Oncology, Sant Andrea Hospital, University La Sapienza, Rome, Italy
    Radiat Oncol 4:42. 2009
    ..Because of the long natural history of benign meningiomas, larger series and longer follow-up are necessary to compare results and toxicity of different techniques...
  44. ncbi Carbon ion radiotherapy for pediatric patients and young adults treated for tumors of the skull base
    Stephanie E Combs
    Department of Radiation Oncology, University Hospital of Heidelberg, Heidelberg, Germany
    Cancer 115:1348-55. 2009
    ..The current study was conducted to evaluate the outcome of carbon ion radiotherapy (RT) in children and young adults with skull base chordomas and chondrosarcomas...
  45. pmc CyberKnife radiosurgery in the treatment of complex skull base tumors: analysis of treatment planning parameters
    Sean P Collins
    Department of Neurosurgery, Georgetown University Hospital, USA
    Radiat Oncol 1:46. 2006
    ..In this study, we investigate whether acceptable treatment plans with excellent conformity and homogeneity can be generated for complex skull base tumors using the Cyberknife radiosurgical system...
  46. ncbi Skull-base metastases
    Florence Laigle-Donadey
    Fédération de Neurologie Mazarin, Groupe Hospitalier Pitie Salpetriere, 47 Boulevard de l Hopital, 75651, Paris Cedex 13, France
    J Neurooncol 75:63-9. 2005
    ..The overall prognosis is poor, with an overall median survival of about 2.5 years, probably because skull-base metastases appear late in the course of the disease...
  47. ncbi Radiosurgery for large-volume (> 10 cm3) benign meningiomas
    Jonathan M Bledsoe
    Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Neurosurg 112:951-6. 2010
    ..Stereotactic radiosurgery (SRS) has proven to be a safe and effective treatment for many patients with intracranial meningiomas. Nevertheless, the morbidity associated with radiosurgery of larger meningiomas is poorly understood...
  48. ncbi Effect of 11C-methionine-positron emission tomography on gross tumor volume delineation in stereotactic radiotherapy of skull base meningiomas
    Sabrina T Astner
    Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
    Int J Radiat Oncol Biol Phys 72:1161-7. 2008
    ....
  49. ncbi PET/CT of skull base meningiomas using 2-18F-fluoro-L-tyrosine: initial report
    Isabelle Rutten
    Department of Radiotherapy, C H U of Liège, Liege, Belgium
    J Nucl Med 48:720-5. 2007
    ..We report our results with PET/CT and 2-(18)F-fluoro-L-tyrosine ((18)F-TYR), a marker of amino acid transport, as part of the yearly follow-up of irradiated patients...
  50. ncbi Postoperative spot-scanning proton radiation therapy for chordoma and chondrosarcoma in children and adolescents: initial experience at paul scherrer institute
    Hans Peter Rutz
    Center for Proton Radiation Therapy, Paul Scherrer Institute, Villigen, Switzerland
    Int J Radiat Oncol Biol Phys 71:220-5. 2008
    ..To evaluate postoperative spot-scanning proton radiation therapy (PT) and intensity-modulated PT (IMPT) for chordoma and chondrosarcoma in pediatric patients...
  51. ncbi Stereotactic radiosurgery and hypofractionated stereotactic radiotherapy for residual or recurrent cranial base and cervical chordomas
    S D Chang
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
    Neurosurg Focus 10:E5. 2001
    ..The authors review their experience in using linear accelerator (LINAC) stereotactic radiosurgery to treat patients with recurrent and/or residual cranial base and cervical chordomas...
  52. ncbi Skull base chordomas: overview of disease, management options, and outcome
    G Lanzino
    Division of Neuropathology, Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 10:E12. 2001
    ..Recurrences are common, although in a subset of patients prolonged disease-free survival is demonstrated...
  53. ncbi Chordomas of the skull base: follow-up review and prognostic factors
    B O Colli
    Division of Neurosurgery, Department of Surgery, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
    Neurosurg Focus 10:E1. 2001
    ..The authors analyze the data and prognostic factors obtained during the follow-up period (range 1-150 months, median 38 months) in 53 patients with craniocervical junction chordoma and 10 patients with chondrosarcoma...
  54. ncbi Postoperative Gamma Knife surgery for benign meningiomas of the cranial base
    Laurence Davidson
    Department of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Neurosurg Focus 23:E6. 2007
    ..The authors analyzed the mid- and long-term results obtained in patients treated with postresection Gamma Knife surgery (GKS) for residual or recurrent benign meningiomas of the cranial base...
  55. ncbi Gamma knife radiosurgery for skull-base meningiomas
    Masami Takanashi
    Department of Neurosurgery, Nakamura Memorial Hospital, Sapporo, Hakkaido, Japan
    Prog Neurol Surg 22:96-111. 2009
    ....
  56. ncbi Gamma Knife surgery for skull base chordomas and chondrosarcomas
    Toshinori Hasegawa
    Department of Neurosurgery, Gamma Knife Center, Komaki City Hospital, Komaki, Japan
    J Neurosurg 107:752-7. 2007
    ..The purpose of this study was to evaluate radiosurgical outcomes in skull base chordomas and chondrosarcomas, and to determine which tumors are appropriate for stereotactic radiosurgery as adjuvant therapy following maximum tumor resection...
  57. ncbi Gamma knife radiosurgery for skull base meningiomas: long-term radiologic and clinical outcome
    Jung Ho Han
    Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
    Int J Radiat Oncol Biol Phys 72:1324-32. 2008
    ..To analyze the long-term outcomes in patients with skull base meningiomas (SBMNGs) treated with Gamma Knife radiosurgery (GKRS)...
  58. ncbi Chordomas and chondrosarcomas of the skull base: comparative analysis of clinical results in 30 patients
    Young Hyun Cho
    Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Neurosurg Rev 31:35-43; discussion 43. 2008
    ..As the biological behavior of chordoma is much more aggressive than that of chondrosarcoma in the skull base, one should make a distinction between these entities to plan an optimal treatment strategy...
  59. ncbi Radiosurgery for chordomas and chondrosarcomas of the skull base
    Juan J Martin
    Department of Neurological Surgery, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Neurosurg 107:758-64. 2007
    ..The authors evaluated the effect of stereotactic radiosurgery (SRS) on local tumor control and survival...
  60. ncbi Radiosurgery/stereotactic radiotherapy in the therapeutical concept for skull base meningiomas
    K Hamm
    Abteilung für stereotaktische Neurochirurgie und Radiochirurgie, HELIOS Klinikum Erfurt GmbH, Erfurt, Germany
    Zentralbl Neurochir 69:14-21. 2008
    ..Stereotactically guided radiation therapy - radiosurgery (RS) or stereotactic radiotherapy (SRT) - offers an additional or alternate treatment option for those patients. We evaluated local control rates, symptomatology, and toxicity...
  61. ncbi Effectiveness of carbon ion radiotherapy in the treatment of skull-base chordomas
    Daniela Schulz-Ertner
    Department of Radiation Oncology, University of Heidelberg, Heidelberg
    Int J Radiat Oncol Biol Phys 68:449-57. 2007
    ..The aim of this study was to evaluate the effectiveness and toxicity of carbon ion radiotherapy in chordomas of the skull base...
  62. ncbi Intensity-modulated radiotherapy for complex-shaped meningioma of the skull base: long-term experience of a single institution
    Stefanie Milker-Zabel
    Department of Clinical Radiology, Radiation Therapy, University of Heidelberg, Germany
    Int J Radiat Oncol Biol Phys 68:858-63. 2007
    ..We analyzed our long-term experience with intensity-modulated radiotherapy (IMRT) in patients with complex-shaped meningioma of the skull base...
  63. ncbi Petroclival meningiomas: multimodality treatment and outcomes at long-term follow-up
    Sabareesh K Natarajan
    Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
    Neurosurgery 60:965-79; discussion 979-81. 2007
    ..To evaluate patients' clinical outcome, survival, and performance status, at the long-term follow-up evaluation after aggressive microsurgical resection of petroclival meningiomas...
  64. ncbi Chordomas of the skull base: surgical management and outcome
    Amir Samii
    International Neuroscience Institute, Hannover, Germany
    J Neurosurg 107:319-24. 2007
    ..The goal of this study was to report on the surgical management of skull base chordomas and to evaluate both the short- and long-term treatment outcomes...
  65. ncbi Skull base approaches and gamma knife radiosurgery for multimodality treatment of skull base tumors
    Paul C Francel
    Department of Neurosurgery, University of Oklahoma, Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    J Neurosurg 97:674-6. 2002
    ..Retrospective data were collected from 71 patients with skull base tumors who were treated from November 1996 to December 2000, all of whom underwent follow-up evaluation at 1 year or more...
  66. ncbi Carbon ion radiotherapy of skull base chondrosarcomas
    Daniela Schulz-Ertner
    Department of Radiation Oncology, University of Heidelberg, Heidelberg, Germany
    Int J Radiat Oncol Biol Phys 67:171-7. 2007
    ..To evaluate the effectiveness and toxicity of carbon ion radiotherapy in chondrosarcomas of the skull base...
  67. ncbi Successful treatment of a skull base malignant rhabdoid tumor with surgery, chemotherapy and gamma Knife-based stereotactic radiosurgery in a young child
    Thomas C Witt
    Neurosurgery, Indiana University Medical Center, Indianapolis, Indiana, USA
    Stereotact Funct Neurosurg 85:310-3. 2007
    ..There were no obvious endocrine deficits or growth abnormalities at last follow-up. Gamma Knife-based stereotactic radiosurgery may have a role in the management of very young children with skull base tumors...
  68. ncbi Cyberknife radiosurgery for basal skull plasmacytoma
    Eric T Wong
    Brain Tumor Center and Neuro Oncology Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Neuroimaging 16:361-3. 2006
    ..To our knowledge, this is a first case of successful Cyberknife radiosurgery of a medullary plasmacytoma...
  69. ncbi Gamma-knife radiosurgery for cranial base meningiomas: experience of tumor control, clinical course, and morbidity in a follow-up of more than 8 years
    Iris Zachenhofer
    Department of Neurosurgery, Medical University of Vienna, Vienna, Austria
    Neurosurgery 58:28-36; discussion 28-36. 2006
    ..However, reports of long-term results are still sparse. We therefore performed this study to analyze the long-term results of GKRS treatment of cranial base meningiomas, following our previously published early follow-up experience...
  70. ncbi Temporal bone and lateral skull base malignancy: experience and results with 81 patients
    S Manolidis
    The Bobby R Alford Department of Otolaryngology, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Otol 19:S1-15. 1998
    ..Cranial nerve deficits and complications are frequent. The success rate of treatment is dependent on histology and disease extent...
  71. ncbi Sphenoid wing meningioma en plaque: a clinical review
    S Honeybul
    Wessex Neurological Centre, UK
    Acta Neurochir (Wien) 143:749-57; discussion 758. 2001
    ..By using well established craniofacial techniques good disease control can be achieved with minimal morbidity and good functional and cosmetic results...
  72. ncbi Linac radiosurgery for skull base meningiomas
    A T Villavicencio
    Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA 02115, USA
    Acta Neurochir (Wien) 143:1141-52. 2001
    ..Radiosurgery is a low-morbidity, effective technique as adjunct and sometimes primary treatment of small to moderate-sized meningiomas of the skull base...
  73. ncbi Lateral skull base malignancies
    Benjamin M McGrew
    Hawaiian Island Ear, Nose, and Throat Specialists, Honolulu, Hawaii, USA
    Neurosurg Focus 12:e8. 2002
    ..As advances in skull base surgical techniques have been made, complete resection has increasingly been achieved. This has resulted in improved survival rates and local tumor control...
  74. ncbi Gamma knife radiosurgery for recurrent salivary gland malignancies involving the base of skull
    Nancy Lee
    Department of Radiation Oncology, University of California San Francisco, 505 Parnassus Ave, L 08 Box 0226, San Francisco, California 94143 0226, USA
    Head Neck 25:210-6. 2003
    ..The management of skull base recurrence of salivary gland tumors is challenging, because complete surgical resection and fractionated reirradiation are seldom possible. Experience is being gained with radiosurgery for this indication...
  75. ncbi Management of malignant tumors of the anterior and anterolateral skull base
    Thomas C Origitano
    Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, USA
    Neurosurg Focus 12:e7. 2002
    ..The authors describe an institutional experience in performing 54 combined anterior-anterolateral cranial base resections for malignant disease...
  76. ncbi Anterior skull base surgery for malignant tumors: a multivariate analysis of 27 years of experience
    Brandon G Bentz
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, New York 10021, USA
    Head Neck 25:515-20. 2003
    ..Few studies have examined prognostic factors that have an impact on outcomes in anterior skull base surgery by multivariate analysis...
  77. ncbi The evolving role of stereotactic radiosurgery for patients with skull base tumors
    Bruce E Pollock
    Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Neurooncol 69:199-207. 2004
    ..Follow-up beyond 10 years is still needed to better define long-term results of radiosurgery and the incidence of radiation-induced neoplasms after radiosurgery...
  78. ncbi Preservation of cranial nerve function following Gamma Knife radiosurgery for benign skull base meningiomas: experience in 121 patients with follow-up of 5 to 9.8 years
    S Eustacchio
    Department of Neurosurgery, Karl Franzens University, Graz, Austria
    Acta Neurochir Suppl 84:71-6. 2002
    ..In this study we evaluated the effect of Gamma Knife Radiosurgery (GKRS) in 121 patients with benign basal meningiomas after a follow-up of 5 to 9.8 years...
  79. ncbi Radiation therapy for chordoma and chondrosarcoma of the skull base and the cervical spine. Prognostic factors and patterns of failure
    Georges Noel
    Centre de protonthérapie d Orsay, Orsay, France
    Strahlenther Onkol 179:241-8. 2003
    ....
  80. ncbi Skull base chordoma
    William M Mendenhall
    Department of Radiation Oncology, University of Florida Health Science Center, PO Box 100385, Gainesville, FL 32610 0385, USA
    Head Neck 27:159-65. 2005
    ..Our purpose was to discuss the optimal treatment and outcomes for patients with skull base chordomas...
  81. ncbi Results of spot-scanning proton radiation therapy for chordoma and chondrosarcoma of the skull base: the Paul Scherrer Institut experience
    Damien C Weber
    Department of Radiation Medicine, Proton Therapy Program, Paul Scherrer Institut, Villigen, Switzerland
    Int J Radiat Oncol Biol Phys 63:401-9. 2005
    ..To assess the clinical results of spot scanning proton beam radiation therapy (PT) in the treatment of skull base chordomas and low-grade chondrosarcomas (CS)...
  82. ncbi Long-term results of stereotactic gamma radiosurgery of meningiomas
    T Kobayashi
    Department of Neurosurgery, Gamma Knife Center, Komaki City Hospital, Komaki City, Japan
    Surg Neurol 55:325-31. 2001
    ..CONCLUSION: Gamma radiosurgery is effective and safe for meningiomas to control residual or recurrent tumors after surgery and initial tumors, with acceptable side effects and rate of tumor progression...
  83. pmc Long term experience of gamma knife radiosurgery for benign skull base meningiomas
    W Kreil
    Department of Neurosurgery, Medical University Graz, Graz, Austria
    J Neurol Neurosurg Psychiatry 76:1425-30. 2005
    ....
  84. ncbi A new classification for malignant tumors involving the anterior skull base
    G Cantu
    Unit of Cranio Maxillo Facial Surgery, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
    Arch Otolaryngol Head Neck Surg 125:1252-7. 1999
    ..To propose our clinical classification of malignant ethmoid tumors and to compare it with the last American Joint Committee on Cancer (AJCC)-Union Internationale Contre le Cancer (UICC) classification, published in 1997...
  85. ncbi Skull-base invasion of nasopharyngeal carcinoma: magnetic resonance imaging findings and therapeutic implications
    T Nishioka
    Department of Radiology, School of Medicine, Hokkaido University, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 47:395-400. 2000
    ..To evaluate the value of skull-base abnormality on MRI for predicting local recurrence in nasopharyngeal carcinoma...
  86. ncbi Radiosurgery as alternative treatment for skull base meningiomas
    G Pendl
    Department of Neurosurgery, Medical School and University, Graz, Austria
    J Clin Neurosci 8:12-4. 2001
    ..Due to excellent tumour control rate, good clinical outcome and a low complication rate GKRS represents not only an attractive additional treatment option for basal meningiomas, but may even replace microsurgery in selected cases...
  87. ncbi LINAC radiosurgery in skull base meningiomas
    R Deinsberger
    Department of Neurosurgery, Klagenfurt General Hospital, Klagenfurt, Austria
    Minim Invasive Neurosurg 47:333-8. 2004
    ..By combining microsurgery and radiosurgery we can achieve high tumor control rates with an acceptable low morbidity and a high level of quality of life...
  88. ncbi High efficacy of fractionated stereotactic radiotherapy of large base-of-skull meningiomas: long-term results
    J Debus
    Department of Radiation Oncology, University of Heidelberg, and Research Program, Radiological Diagnostics and Therapy, German Cancer Research Center, Heidelberg, Germany
    J Clin Oncol 19:3547-53. 2001
    ..We analyzed the long-term results of patients with skull-base meningiomas treated by a new approach with high-precision fractionated stereotactic radiotherapy...
  89. ncbi Evaluation of fractionated radiotherapy and gamma knife radiosurgery in cavernous sinus meningiomas: treatment strategy
    Philipe Metellus
    Department of Neurosurgery, Timone Hospital, University of Aix Marseille II, Marseille, France
    Neurosurgery 57:873-86; discussion 873-86. 2005
    ..To investigate the respective role of fractionated radiotherapy (FR) and gamma knife stereotactic (GKS) radiosurgery in cavernous sinus meningioma (CSM) treatment...
  90. ncbi Chordomas of the base of the skull and upper cervical spine. One hundred patients irradiated by a 3D conformal technique combining photon and proton beams
    Georges Noel
    Institut Curie CPO batiment 101, University Campus, 91898 Orsay, Cedex, France
    Acta Oncol 44:700-8. 2005
    ..The role of surgical resection remains paramount, and a trial of dose escalation would have to consider an increase in the dose to critical organs, especially as current results indicate the low toxicity of this treatment...
  91. ncbi Radiotherapy alone or after subtotal resection for benign skull base meningiomas
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Cancer 98:1473-82. 2003
    ..The objective of the current study was to analyze the long-term local control and complications in a series of patients who were treated with radiotherapy for benign skull base meningiomas...
  92. ncbi The outcome of surgical treatment for tumors of the craniocervical junction
    Surachai Khaoroptham
    Division of Neurological Surgery, Department of Surgery, Faculty of Medicine, Chulalongkorn University, Rama IV Rd, Patumwan Bangkok 10230, Thailand
    J Med Assoc Thai 90:1450-7. 2007
    ..The authors report the clinical, radiological, and surgicalfindings ofpatients with craniocervical junction tumors surgically treated in the institution over the last 8 years...
  93. ncbi A case of intracranial hypoglossal neurinoma without hypoglossal nerve palsy: operative view of the preserved rostral trunk
    Y Kikkawa
    Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Minim Invasive Neurosurg 50:296-9. 2007
    ..The tumor only developed intracranially, and since the rostral trunk of the hypoglossal nerve was intact, the patient did not present with hypoglossal nerve palsy preoperatively...
  94. ncbi Microsurgical total removal of olfactory groove meningiomas and reconstruction of the invaded skull bases
    Yuguang Liu
    Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, China
    Int Surg 92:167-73. 2007
    ....
  95. ncbi Subarachnoid hemorrhage associated with clival chordoma--case report
    Reiko Nakau
    Department of Neurosurgery, Asahikawa Red Cross Hospital, Asahikawa, Hokkaido
    Neurol Med Chir (Tokyo) 43:605-7. 2003
    ..The diagnosis was clival chordoma. Subarachnoid hemorrhage in chordoma seems to occur by spreading of intratumoral hemorrhage into the subarachnoid space due to dural invasion...
  96. ncbi Visual complications of proton beam therapy for clival chordoma
    J Bowyer
    Department of Ophthalmology, Walton Hospital, Liverpool, UK
    Eye (Lond) 17:318-23. 2003
    ..Combining maximal surgical resection with high-dose proton radiation therapy is reported to be currently the best management of patients with clival chordoma...
  97. ncbi Submentotracheal intubation for skull base neurosurgery
    Indu Bala
    J Neurosurg Anesthesiol 16:259-60. 2004
  98. ncbi [Post-processing of radiological data for preoperative planning in skull base surgery]
    G Strauss
    Klinik und Poliklinik für HNO Heilkunde Plastische Operationen
    Laryngorhinootologie 83:157-63. 2004
    ..e. intraoperative navigation and visualization). Evidence based medicine will use digital data of surgical planning...
  99. ncbi [Transmaxillary approach for micro resection of clivus tumors, clinical analysis of 16 cases]
    Ning Liu
    Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Yi Xue Za Zhi 83:1490-2. 2003
    ..To investigate the indications, key point, advantages, and disadvantages of transmaxillary approach for microsurgical removal of clivus tumors...
  100. ncbi A large planum sphenoidale meningioma with sinonasal extension in a child. Case report and review of the literature
    Alex Mohit
    Department of Neurological Surgery, Children s Hospital and Regional Medical Center and University of Washington School of Medicine, Seattle, WA 98105, USA
    Pediatr Neurosurg 39:270-4. 2003
    ..The advantages of combining the bifrontal craniotomy with a transfacial split provided the added exposure to maximize the extent of resection...
  101. ncbi Removal of clival chordoma in an adolescent thorough combned pterional transsylvian and anterior temporal approach
    Mustafa Bozbuga
    Dr Lültfi Kirdar Kartal Egitim ve Araştirma Hastanesi, Neurosurgery, Istanbul, Turkey
    Turk Neurosurg 17:55-9. 2007
    ..The tumor was located extradurally. The resected tumor had the typical histological and immunohistochemical characteristics of chordoma. No radiation therapy or chemotherapy was administered...

Research Grants2

  1. Cognitive Studies of Temporal Lobe Function in Man
    Guila Glosser; Fiscal Year: 2003
    ..b) To assess the usefulness of presurgical fMRI activation measures during an allocentric spatial memory task for predicting memory performance following ATL. ..
  2. Therapeutic Studies of Primary CNS Malignancies-NABTT
    Gene Barnett; Fiscal Year: 2008
    ..abstract_text> ..