hip osteoarthritis

Summary

Summary: Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion.

Top Publications

  1. pmc EULAR evidence based recommendations for the management of hip osteoarthritis: report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    W Zhang
    Academic Rheumatology, University of Nottingham, UK
    Ann Rheum Dis 64:669-81. 2005
  2. doi Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: a case-control study
    Michael Doherty
    University of Nottingham, Nottingham University Hospitals Trust, Nottingham, UK
    Arthritis Rheum 58:3172-82. 2008
  3. ncbi Hip dysplasia: a significant risk factor for the development of hip osteoarthritis. A cross-sectional survey
    S Jacobsen
    Department of Orthopaedic Surgery, Hvidovre University Hospital of Copenhagen, Denmark
    Rheumatology (Oxford) 44:211-8. 2005
  4. pmc Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement
    F Tubach
    Institut National de la Sante et de la Recherche Medicale, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
    Ann Rheum Dis 64:29-33. 2005
  5. pmc Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: the Rotterdam Study
    M Reijman
    Department of Orthopedics, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Ann Rheum Dis 66:158-62. 2007
  6. ncbi Reduced muscle radiological density, cross-sectional area, and strength of major hip and knee muscles in 22 patients with hip osteoarthritis
    Anton Rasch
    Department of Orthopedics, Karolinska Institutet at Dandeyd Hospital, SE 182 88 Stockholm, Sweden
    Acta Orthop 78:505-10. 2007
  7. pmc Responsiveness of the WOMAC osteoarthritis index as compared with the SF-36 in patients with osteoarthritis of the legs undergoing a comprehensive rehabilitation intervention
    F Angst
    Clinic of Rheumatology and Rehabilitation Zurzach, Switzerland
    Ann Rheum Dis 60:834-40. 2001
  8. pmc Effect of therapeutic exercise for hip osteoarthritis pain: results of a meta-analysis
    Gabriela Hernández-Molina
    Boston University, Boston, Massachusetts, USA
    Arthritis Rheum 59:1221-8. 2008
  9. ncbi Pelvic and lower limb compensatory actions of subjects in an early stage of hip osteoarthritis
    E Watelain
    Laboratoire d analyse du Mouvement, Service d Exploration Neurophysiologique Hôpital Roger Salengro, Centre Hospitalier Regional Universitaire CHRU, Lille, France
    Arch Phys Med Rehabil 82:1705-11. 2001
  10. pmc Muscle strength, gait, and balance in 20 patients with hip osteoarthritis followed for 2 years after THA
    Anton Rasch
    Stockholm Spine Center, Löwenströmska Hospital, Upplands Vasby, Sweden
    Acta Orthop 81:183-8. 2010

Detail Information

Publications304 found, 100 shown here

  1. pmc EULAR evidence based recommendations for the management of hip osteoarthritis: report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    W Zhang
    Academic Rheumatology, University of Nottingham, UK
    Ann Rheum Dis 64:669-81. 2005
    To develop evidence based recommendations for the management of hip osteoarthritis (OA).
  2. doi Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: a case-control study
    Michael Doherty
    University of Nottingham, Nottingham University Hospitals Trust, Nottingham, UK
    Arthritis Rheum 58:3172-82. 2008
    To determine whether 2-dimensional measures of femoral head shape and angle are associated with hip osteoarthritis (OA).
  3. ncbi Hip dysplasia: a significant risk factor for the development of hip osteoarthritis. A cross-sectional survey
    S Jacobsen
    Department of Orthopaedic Surgery, Hvidovre University Hospital of Copenhagen, Denmark
    Rheumatology (Oxford) 44:211-8. 2005
    ..The aim of this cross-sectional survey of 2232 women and 1336 men (age range 20-91 yr) was to investigate individual risk factors for hip joint osteoarthritis (OA)...
  4. pmc Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement
    F Tubach
    Institut National de la Sante et de la Recherche Medicale, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
    Ann Rheum Dis 64:29-33. 2005
    ..In clinical trials, at the group level, results are usually reported as mean and standard deviation of the change in score, which is not meaningful for most readers...
  5. pmc Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: the Rotterdam Study
    M Reijman
    Department of Orthopedics, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Ann Rheum Dis 66:158-62. 2007
    To investigate the relationship between body mass index (BMI) and the incidence and progression of radiological knee as well as of radiological hip osteoarthritis.
  6. ncbi Reduced muscle radiological density, cross-sectional area, and strength of major hip and knee muscles in 22 patients with hip osteoarthritis
    Anton Rasch
    Department of Orthopedics, Karolinska Institutet at Dandeyd Hospital, SE 182 88 Stockholm, Sweden
    Acta Orthop 78:505-10. 2007
    Patients with hip osteoarthritis (OA) typically suffer joint pain, and often experience muscular weakness...
  7. pmc Responsiveness of the WOMAC osteoarthritis index as compared with the SF-36 in patients with osteoarthritis of the legs undergoing a comprehensive rehabilitation intervention
    F Angst
    Clinic of Rheumatology and Rehabilitation Zurzach, Switzerland
    Ann Rheum Dis 60:834-40. 2001
    ....
  8. pmc Effect of therapeutic exercise for hip osteoarthritis pain: results of a meta-analysis
    Gabriela Hernández-Molina
    Boston University, Boston, Massachusetts, USA
    Arthritis Rheum 59:1221-8. 2008
    ..To provide more targeted recommendations for the hip, we gathered evidence for the efficacy of exercise for hip OA from randomized controlled trials...
  9. ncbi Pelvic and lower limb compensatory actions of subjects in an early stage of hip osteoarthritis
    E Watelain
    Laboratoire d analyse du Mouvement, Service d Exploration Neurophysiologique Hôpital Roger Salengro, Centre Hospitalier Regional Universitaire CHRU, Lille, France
    Arch Phys Med Rehabil 82:1705-11. 2001
    To determine if compensatory actions take place at the pelvis and other joints of the affected lower limb in subjects who were in an early stage of hip osteoarthritis (OA).
  10. pmc Muscle strength, gait, and balance in 20 patients with hip osteoarthritis followed for 2 years after THA
    Anton Rasch
    Stockholm Spine Center, Löwenströmska Hospital, Upplands Vasby, Sweden
    Acta Orthop 81:183-8. 2010
    Patients with hip osteoarthritis (OA) have muscular weakness, impaired balance, and limp. Deficits in the different limb muscles and their recovery courses are largely unknown, however...
  11. doi Immediate weight bearing after uncemented total hip arthroplasty with an anteverted stem: a prospective randomized comparison using radiostereometry
    Truike M Thien
    Department of Orthopaedics, Sahlgrenska University Hospital, Molndal, Sweden
    Acta Orthop 78:730-8. 2007
    ..In uncemented total hip arthroplasty with hydroxyapatite coating, early weight bearing is frequently practiced but there is still not much evidence to support this recommendation...
  12. doi Economic burden of knee and hip osteoarthritis in Spain
    Estibaliz Loza
    Hospital Clinico San Carlos, Madrid, Spain
    Arthritis Rheum 61:158-65. 2009
    ..To estimate the direct and indirect osteoarthritis (OA)-attributable costs and predictors of costs of knee and hip OA in Spain...
  13. ncbi Standardized incidence rates of total hip replacement for primary hip osteoarthritis in the 5 Nordic countries: similarities and differences
    L Stefan Lohmander
    Department of Orthopaedics, Lund University, Sweden
    Acta Orthop 77:733-40. 2006
    ..countries provide an opportunity to compare age- and sex-standardized annual incidence of primary total hip replacement (THR) and types of implants used for primary hip osteoarthritis (OA) in Denmark, Finland, Iceland, Norway and Sweden.
  14. doi Effect of glucosamine sulphate on joint space narrowing, pain and function in patients with hip osteoarthritis; subgroup analyses of a randomized controlled trial
    R M Rozendaal
    Department of General Practice, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Osteoarthritis Cartilage 17:427-32. 2009
    ..sulphate (GS) did not have an effect on the symptoms and progression of primary care patients with hip osteoarthritis (OA)...
  15. doi Hip resurfacings revised for inflammatory pseudotumour have a poor outcome
    G Grammatopolous
    Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Services University of Oxford, Headington, Oxford OX37LD, UK
    J Bone Joint Surg Br 91:1019-24. 2009
    ..The outcome of revision for pseudotumour is poor and consideration should be given to early revision to limit the extent of the soft-tissue destruction. The outcome of resurfacing revision for other causes is good...
  16. doi Role of European mitochondrial DNA haplogroups in the prevalence of hip osteoarthritis in Galicia, Northern Spain
    I Rego
    Osteoarticular and Aging Research Laboratory, Biomedical Center Research, INIBIC Rheumatology Division, CH Universitario A Coruña, Coruna, Spain
    Ann Rheum Dis 69:210-3. 2010
    To analyse the mitochondrial DNA (mtDNA) haplogroups of patients with hip osteoarthritis (OA) and those of healthy controls in a Spanish population.
  17. pmc Epidemiological profile of symptomatic osteoarthritis in older adults: a population based study in Dicomano, Italy
    A Mannoni
    Rheumatology Unit, I O T, Azienda Sanitaria di Firenze, Italy
    Ann Rheum Dis 62:576-8. 2003
    ..To assess the prevalence of hand, hip, and knee osteoarthritis (OA) in an older Italian community dwelling population and its association with disability...
  18. ncbi Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women
    Nancy E Lane
    University of California, Davis, Sacramento, CA 95817, USA
    Arthritis Rheum 56:3319-25. 2007
    To determine whether serum levels of 2 Wnt signaling antagonists, Frizzled-related protein (FRP) and Dkk-1, are associated with the development and progression of radiographic hip osteoarthritis (RHOA).
  19. ncbi Mortality after total hip replacement: 0-10-year follow-up of 39,543 patients in the Norwegian Arthroplasty Register
    S A Lie
    Division for Medical Statistics, Armauer Hansens Hus, University of Bergen, Haukeland Sykehus, Norway
    Acta Orthop Scand 71:19-27. 2000
    ..65). During the first 60 postoperative days, all patient categories had a higher mortality than the general population (0.8% mortality, SMR = 1.39)...
  20. doi Persisting muscle atrophy two years after replacement of the hip
    A Rasch
    Department of Clinical Sciences, Division of Orthopaedic Surgery, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden
    J Bone Joint Surg Br 91:583-8. 2009
    ..4 Hounsfield units; p = 0.022). Thus, there was persistent muscle atrophy in muscles acting about the hip two years after THR. We suggest that an earlier operation or a more intensive rehabilitation may reverse these changes...
  21. ncbi Early identification of radiographic osteoarthritis of the hip using an active shape model to quantify changes in bone morphometric features: can hip shape tell us anything about the progression of osteoarthritis?
    Jennifer S Gregory
    University of Aberdeen, Department of Orthopaedics, Aberdeen, UK
    Arthritis Rheum 56:3634-43. 2007
    ..In this study, an active shape model (ASM) of the proximal femur was used to determine whether morphologic changes to the bone could be quantified and used as a marker of hip OA...
  22. ncbi Influence of work on the development of osteoarthritis of the hip: a systematic review
    A Lievense
    Department of General Practice, University Hospital Rotterdam, The Netherlands
    J Rheumatol 28:2520-8. 2001
    ..To evaluate the evidence for the influence of physical workload on the occurrence of osteoarthritis (OA) of the hip...
  23. ncbi Asymmetric knee loading in advanced unilateral hip osteoarthritis
    Najia Shakoor
    Section of Rheumatology, Rush Medical College, Chicago, Illinois 60612 3862, USA
    Arthritis Rheum 48:1556-61. 2003
    Subjects with unilateral end-stage hip osteoarthritis (OA) who undergo total hip replacement (THR) preferentially require subsequent replacement of the contralateral knee compared with the ipsilateral knee...
  24. pmc Evaluation of clinically relevant states in patient reported outcomes in knee and hip osteoarthritis: the patient acceptable symptom state
    F Tubach
    Institut National de la Santé et de la Recherche Médicale E 0357, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
    Ann Rheum Dis 64:34-7. 2005
    ..The patient acceptable symptom state (PASS) is the value beyond which patients can consider themselves well. This concept can help in interpreting results of clinical trials...
  25. pmc Urinary type II collagen C-telopeptide levels are increased in patients with rapidly destructive hip osteoarthritis
    P Garnero
    INSERM Research Unit 403, Lyon, France
    Ann Rheum Dis 62:939-43. 2003
    ..To compare type II collagen degradation using a new urinary specific marker in patients with rapidly destructive and those with slowly progressive hip OA...
  26. ncbi Prevalence and distribution of hip and knee joint replacements and hip implants in older Americans by the end of life
    David Melzer
    Demography and Biometry Laboratory, National Institute on Aging, Bethesda, Maryland, USA
    Aging Clin Exp Res 15:60-6. 2003
    ..in people aged 65 and over who died in the US in 1993, and to measure mobility outcomes during their last year of life...
  27. ncbi Imageless navigation for insertion of the acetabular component in total hip arthroplasty: is it as accurate as CT-based navigation?
    T Kalteis
    Department of Orthopaedic Surgery, University of Regensburg, Asklepios Klinikum Bad Abbach, Kaiser Karl V Allee 3, 93077 Bad Abbach, Germany
    J Bone Joint Surg Br 88:163-7. 2006
    ..001). The duration of the operation was increased by eight minutes with imageless and by 17 minutes with CT-based navigation. Imageless navigation proved as reliable as that using CT in positioning the acetabular component...
  28. ncbi The operation of the century: total hip replacement
    Ian D Learmonth
    Department of Orthopaedics, Bristol Royal Infirmary, Bristol BS2 8HW, UK
    Lancet 370:1508-19. 2007
    ..Universal economic constraints in healthcare services dictate that further developments in total hip replacement will be governed by their cost-effectiveness...
  29. doi Functioning and disability in patients with hip osteoarthritis with mild to moderate pain
    Karin Rydevik
    Norwegian Research Center for Active Rehabilitation NAR, Department of Orthopedics, Oslo University Hospital and Hjelp24 Norwegian Sports Medicine Clinic Hjelp24 NIMI, Oslo, Norway
    J Orthop Sports Phys Ther 40:616-24. 2010
    ..Cross-sectional study...
  30. doi Variables associated with the progression of hip osteoarthritis: a systematic review
    Alexis A Wright
    University of Otago, Dunedin, New Zealand
    Arthritis Rheum 61:925-36. 2009
    As populations age and the prevalence of hip osteoarthritis (OA) increases, health care providers must manage increasing demands for services...
  31. doi Associations of occupational tasks with knee and hip osteoarthritis: the Johnston County Osteoarthritis Project
    Kelli D Allen
    Health Services Research and Development Service, Durham Veterans Affairs Medical Center, Durham, North Carolina 27705, USA
    J Rheumatol 37:842-50. 2010
    ..This cross-sectional study examined associations of occupational tasks with radiographic and symptomatic osteoarthritis (OA) in a community-based sample...
  32. doi Association of physical performance with muscle strength and hip range of motion in hip osteoarthritis
    Yong Hao Pua
    The University of Melbourne, Melbourne, Victoria, Australia
    Arthritis Rheum 61:442-50. 2009
    ..whether the associations of physical performance with isometric hip and knee extensors strength and passive hip flexion and internal rotation range of motion (ROM) are nonlinear in community-dwelling adults with hip osteoarthritis (OA).
  33. ncbi Validation of the Spanish version of the WOMAC questionnaire for patients with hip or knee osteoarthritis. Western Ontario and McMaster Universities Osteoarthritis Index
    A Escobar
    Hospital of Basurto, Bilbao, Spain
    Clin Rheumatol 21:466-71. 2002
    ..8. The standardised response mean ranged from 1.3 to 1.9 for patients with hip OA; those with knee OA ranged from 0.8 to 1.5. The Spanish version of WOMAC is a valid, reliable and responsive instrument in patients with hip or knee OA...
  34. ncbi The effect of aquatic exercise and education on lowering fall risk in older adults with hip osteoarthritis
    Cathy M Arnold
    School of Physical Therapy, University of Saskatchewan, Saskatoon, SK, Canada
    J Aging Phys Act 18:245-60. 2010
    To evaluate the effect of aquatic exercise and education on fall risk factors in older adults with hip osteoarthritis (OA).
  35. ncbi OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence
    W Zhang
    University of Edinburgh, Osteoarticular Research Group, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom
    Osteoarthritis Cartilage 15:981-1000. 2007
    ....
  36. doi Low-frequency electric muscle stimulation combined with physical therapy after total hip arthroplasty for hip osteoarthritis in elderly patients: a randomized controlled trial
    Vincent Gremeaux
    Pôle Rééducation Réadaptation, Centre Hospitalier Universitaire de Dijon, INSERM, U887, Dijon, France
    Arch Phys Med Rehabil 89:2265-73. 2008
    To assess the effects of low-frequency electric muscle stimulation associated with usual physiotherapy on functional outcome after total hip arthroplasty (THA) for hip osteoarthritis (OA) in elderly subjects.
  37. ncbi Course of functional status and pain in osteoarthritis of the hip or knee: a systematic review of the literature
    Gabriella M van Dijk
    Netherlands Institute for Health Services Research, Utrecht, The Netherlands
    Arthritis Rheum 55:779-85. 2006
    ..To systematically review studies describing the course of functioning in patients with osteoarthritis (OA) of the hip or knee and identifying potential prognostic factors...
  38. ncbi Quantitative gait analysis of patients with bilateral hip osteoarthritis excluding the influence of walking speed
    Masafumi Kubota
    Division of Physical Therapy and Rehabilitation Medicine, University of Fukui Hospital, 23 Matsuoka Shimoaizuki, Eiheiji, Fukui, 910 1193, Japan
    J Orthop Sci 12:451-7. 2007
    The purpose of this study was to investigate gait characteristics of patients with bilateral hip osteoarthritis (BHO) independent of walking speed.
  39. doi Bone marrow edema pattern in advanced hip osteoarthritis: quantitative assessment with magnetic resonance imaging and correlation with clinical examination, radiographic findings, and histopathology
    Mihra S Taljanovic
    Department of Radiology, The University of Arizona HSC, 1501 N Campbell Ave, Tucson, AZ 85724, USA
    Skeletal Radiol 37:423-31. 2008
    To correlate the amount of bone marrow edema (BME) calculated by magnetic resonance imaging(MRI) with clinical findings, histopathology, and radiographic findings, in patients with advanced hip osteoarthritis(OA).
  40. ncbi Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial
    Rianne M Rozendaal
    Department of General Practice, Erasmus Medical Center, Rotterdam, The Netherlands
    Ann Intern Med 148:268-77. 2008
    ..The effectiveness of glucosamine sulfate as a symptom and disease modifier for osteoarthritis is still under debate...
  41. doi Sclerostin and the regulation of bone formation: Effects in hip osteoarthritis and femoral neck fracture
    Jon Power
    Bone Research Division, Department of Medicine, University of Cambridge, Cambridge, UK
    J Bone Miner Res 25:1867-76. 2010
    ..b>Hip osteoarthritis protects against intracapsular hip fracture...
  42. ncbi Age and waiting time as predictors of outcome after total hip replacement for osteoarthritis
    A K Nilsdotter
    Department of Orthopedics, Halmstad County Hospital, Halmstad, Sweden
    Rheumatology (Oxford) 41:1261-7. 2002
    ..To investigate in a prospective study the relationship between age, pre-operative status, waiting time and post-operative outcome in patients assigned for unilateral total hip replacement (THR) due to osteoarthritis (OA)...
  43. ncbi Progression of radiographic hip osteoarthritis over eight years in a community sample of elderly white women
    Nancy E Lane
    Division of Rheumatology, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    Arthritis Rheum 50:1477-86. 2004
    To describe progression over 8 years in a community-based sample of elderly women with radiographic findings of hip osteoarthritis (RHOA) with or without hip pain.
  44. pmc Prevalence of hip symptoms and radiographic and symptomatic hip osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project
    Joanne M Jordan
    Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, CB 7280, 3300 Thurston Building, Chapel Hill, NC 27599 7280, USA
    J Rheumatol 36:809-15. 2009
    ..To report contemporary estimates of the prevalence of hip-related osteoarthritis (OA) outcomes in African Americans and Caucasians aged>or=45 years...
  45. ncbi A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial
    K Winther
    Department of Clinical Biochemistry, Copenhagen County Hospital Gentofte, 2900 Hellerup, Denmark
    Scand J Rheumatol 34:302-8. 2005
    ..The aim of this study was to determine whether a herbal remedy made from a subspecies of rose-hip (Rosa canina) might reduce symptoms of osteoarthritis and consumption of rescue medication in patients suffering from osteoarthritis...
  46. pmc Hip disability and osteoarthritis outcome score (HOOS)--validity and responsiveness in total hip replacement
    Anna K Nilsdotter
    Department of Orthopedics, Lund University Hospital, Sweden
    BMC Musculoskelet Disord 4:10. 2003
    ..with a younger population were of importance for an older population, and to construct an outcome measure for hip osteoarthritis with improved responsiveness compared to the Western Ontario McMaster osteoarthritis score (WOMAC LK 3.0).
  47. pmc Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up
    Margreth Grotle
    National Resource Centre for Rehabilitation in Rheumatology, Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, POBox 23 Vinderen, 0319 Oslo, Norway
    BMC Musculoskelet Disord 9:132. 2008
    ..The purpose of this study was to investigate the impact of obesity on incident osteoarthritis (OA) in hip, knee, and hand in a general population followed in 10 years...
  48. pmc The Nordic Arthroplasty Register Association: a unique collaboration between 3 national hip arthroplasty registries with 280,201 THRs
    Leif I Havelin
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 80:393-401. 2009
    ..In addition, we plan to study results in patient groups in which the numbers are too small to be studied in the individual countries...
  49. ncbi Development and testing of a reduced WOMAC function scale
    S L Whitehouse
    Orthopaedic Research Unit, Queensland University of Technology, Prince Charles Hospital, Chermside, Brisbane QLD 4001, Australia
    J Bone Joint Surg Br 85:706-11. 2003
    ..Further work is needed to demonstrate its wider applicability...
  50. doi The importance of allocation concealment and patient blinding in osteoarthritis trials: a meta-epidemiologic study
    Eveline Nüesch
    Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
    Arthritis Rheum 61:1633-41. 2009
    ..To evaluate the association of adequate allocation concealment and patient blinding with estimates of treatment benefits in osteoarthritis trials...
  51. pmc Predictors of patient relevant outcome after total hip replacement for osteoarthritis: a prospective study
    A K Nilsdotter
    Department of Orthopaedics, Lund University Hospital, Spenshult Hospital of Rheumatic Diseases, Halmstad, Sweden
    Ann Rheum Dis 62:923-30. 2003
    ..To investigate prospectively long term patient relevant outcomes after unilateral total hip replacement (THR) for osteoarthritis (OA). To identify non-responders to this intervention and patient related predictors of unsatisfactory outcome...
  52. ncbi Movement pattern of the Exeter femoral stem; a radiostereometric analysis of 22 primary hip arthroplasties followed for 5 years
    Anna Stefánsdóttir
    Department of Orthopedics, Hässleholm Kristianstad County Hospital, Sweden
    Acta Orthop Scand 75:408-14. 2004
    ..The design of the Exeter stem may facilitate distal migration, but radiostereometric analysis (RSA) studies have been limited to 2 years of follow-up...
  53. ncbi Osteoporosis and vitamin-D deficiency among postmenopausal women with osteoarthritis undergoing total hip arthroplasty
    Julie Glowacki
    Departments of Orthopedic Surgery and Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Bone Joint Surg Am 85:2371-7. 2003
    ....
  54. ncbi Epidemiology of osteoarthritis: prevalence, risk factors and functional impact
    Maria Chiara Corti
    Department of Medicine, Rheumatology Outpatient Clinic, Camposampiero Hospital, AULSS No 15, Camposampiero, Padova, Italy
    Aging Clin Exp Res 15:359-63. 2003
    ....
  55. ncbi Health-related quality of life and appropriateness of knee or hip joint replacement
    Jose M Quintana
    Unidad de Investigacion, Hospital de Galdakao, Galdakao, Vizcaya, Spain
    Arch Intern Med 166:220-6. 2006
    ..We studied the association between explicit appropriateness criteria for total hip joint replacement (THR) and total knee replacement (TKR) with changes in health-related quality of life of patients undergoing these procedures...
  56. ncbi Primary and revision hip arthroplasty: 5-year outcomes and influence of age and comorbidity
    Anne Lubbeke
    Department of Orthopaedic Surgery, Geneva University Hospital, Geneva, Switzerland
    J Rheumatol 34:394-400. 2007
    ....
  57. pmc Assessment of primary hip osteoarthritis: comparison of radiographic methods using colon radiographs
    T Ingvarsson
    Central Hospital, 600 Akureyri, Iceland
    Ann Rheum Dis 59:650-3. 2000
    ..To compare the reliability of quantitative measurement of minimum hip joint space with a qualitative global assessment of radiological features for estimating the prevalence of primary osteoarthritis (OA) of the hip in colon radiographs...
  58. pmc Outcome of primary resurfacing hip replacement: evaluation of risk factors for early revision
    Gareth H Prosser
    Perth Orthopaedic Institute, Fremantle Hospital and University of Western Australia, Australia
    Acta Orthop 81:66-71. 2010
    ..As a result, the AOANJRR has one of the largest series of resurfacing procedures. This study was undertaken to determine the results of this series and the risk factors associated with revision...
  59. ncbi Population requirement for primary hip-replacement surgery: a cross-sectional study
    S Frankel
    Department of Social Medicine, University of Bristol
    Lancet 353:1304-9. 1999
    ..We set out to estimate the population requirement for primary total hip replacement in England...
  60. ncbi Hip muscle strength and muscle cross sectional area in men with and without hip osteoarthritis
    Merja H Arokoski
    Department of Physical and Rehabilitation Medicine, Kuopio University Hospital and Kuopio University, Kuopio, Finland
    J Rheumatol 29:2185-95. 2002
    To study the hip muscle strength and cross sectional area (CSA) in men with hip osteoarthritis (OA) compared to age and sex matched healthy controls.
  61. pmc Systematic review of the prevalence of radiographic primary hip osteoarthritis
    Simon Dagenais
    Division of Orthopaedics, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
    Clin Orthop Relat Res 467:623-37. 2009
    b>Hip osteoarthritis is a common cause of musculoskeletal pain in older adults and may result in decreased mobility and quality of life...
  62. pmc Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal
    M Reijman
    Department of General Practice, Erasmus MC, Rotterdam, The Netherlands
    Ann Rheum Dis 63:226-32. 2004
    ..and review articles addressing the quality (validity, reliability, applicability) of seven commonly used definitions of hip osteoarthritis (OA) for epidemiological studies in order to use it primarily as a classification criterion.
  63. ncbi Hip osteoarthritis in a rural male population: A prospective population-based register study
    Anders Thelin
    Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology Section, Uppsala University, Uppsala, Sweden
    Am J Ind Med 50:604-7. 2007
    ..A cohort of rural men with urban referents was followed over 13 years to study the risk of developing osteoarthritis of the hip joint...
  64. ncbi Osteoarthritis of the knee and hip and activity: a systematic international review and synthesis (OASIS)
    Eric Vignon
    Universite Claude Bernard, Lyon, France
    Joint Bone Spine 73:442-55. 2006
    ..The goal of this study was to determine which activities in four domains, daily life, exercises, sports and occupational activities, should be recommended, in favor or against, for the patient suffering from knee or hip OA...
  65. ncbi Long-term outcome following total hip arthroplasty: a controlled longitudinal study
    Janet Cushnaghan
    University of Southampton, Southampton, UK
    Arthritis Rheum 57:1375-80. 2007
    ..To assess long-term outcome and predictors of prognosis following total hip arthroplasty (THA) for osteoarthritis (OA)...
  66. doi Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism
    Rainer J Egli
    RMS Foundation, Bettlach, Switzerland
    Arthritis Rheum 60:2055-64. 2009
    ....
  67. ncbi Uncemented total hip arthroplasty for primary osteoarthritis in young patients: a mid-to long-term follow-up study from the Finnish Arthroplasty Register
    Antti Eskelinen
    ORTON Orthopaedic Hospital, Invalid Foundation, Helsinki, Finland
    Acta Orthop 77:57-70. 2006
    ..We evaluated the population-based survival of uncemented THA for primary osteoarthritis (OA) in patients under 55 years of age and the factors affecting survival...
  68. ncbi The effects of a health educational and exercise program for older adults with osteoarthritis for the hip or knee
    M Hopman-Rock
    TNO Prevention and Health, Division of Public Health, Leiden, The Netherlands
    J Rheumatol 27:1947-54. 2000
    ..The program, which consisted of 6 weekly sessions of 2 hours, included health education by a peer and physical exercises taught by a physical therapist...
  69. doi Disability and quality of life of patients with knee or hip osteoarthritis in the primary care setting and factors associated with general practitioners' indication for prosthetic replacement within 1 year
    I Boutron
    INSERM, U738, Paris, France
    Osteoarthritis Cartilage 16:1024-31. 2008
    ....
  70. pmc Body mass indices in patients with disabling hip osteoarthritis
    Ray Marks
    Research Division, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
    Arthritis Res 4:112-6. 2002
    b>Hip osteoarthritis (OA) is a degenerative joint disease that results in substantial morbidity. The disease may be preventable in some instances by reducing risk factors associated with the disease...
  71. ncbi The ratio of osteocytic incorporation to bone matrix formation in femoral neck cancellous bone: an enhanced osteoblast work rate in the vicinity of hip osteoarthritis
    G R Jordan
    Bone Research Group MRC, Department of Medicine, University of Cambridge Clinical School, Addenbrookes Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Calcif Tissue Int 72:190-6. 2003
    ..One possible approach to strengthening bone in osteoporosis might be to enhance the effective lifespan of the osteoblast by modulating TGFb-related pathway activity in its local environment...
  72. pmc Female patients with low systemic BMD are prone to bone loss in Gruen zone 7 after cementless total hip arthroplasty
    Jessica J Alm
    Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Turku University Central Hospital and University of Turku, Finland
    Acta Orthop 80:531-7. 2009
    ..We investigated the association between early changes in periprosthetic bone mineral density (BMD) and patient-related factors...
  73. pmc Effects of activity strategy training on pain and physical activity in older adults with knee or hip osteoarthritis: a pilot study
    Susan L Murphy
    University of Michigan, Ann Arbor, MI, USA
    Arthritis Rheum 59:1480-7. 2008
    ..To examine effects of activity strategy training (AST), a structured rehabilitation program taught by occupational therapists and designed to teach adaptive strategies for symptom control and engagement in physical activity (PA)...
  74. pmc Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females
    John Loughlin
    Institute of Musculoskeletal Sciences, Botnar Research Centre, Nuffield Orthopaedic Centre, University of Oxford, Oxford OX1 7LD, United Kingdom
    Proc Natl Acad Sci U S A 101:9757-62. 2004
    ..Hence, functional polymorphisms within FRZB confer susceptibility for hip OA in females and implicate the wnt signaling pathway in the pathogenesis of this disease...
  75. ncbi Structural effect of avocado/soybean unsaponifiables on joint space loss in osteoarthritis of the hip
    Michel Lequesne
    Hopital Leopold Bellan, Paris, France
    Arthritis Rheum 47:50-8. 2002
    ..To evaluate the structural effect of avocado/soybean unsaponifiables (ASU) in the treatment of patients with symptomatic osteoarthritis (OA) of the hip...
  76. doi BMI and severity of clinical and radiographic signs of hip osteoarthritis
    Anne Lubbeke
    Division of Orthopaedic Surgery, Geneva University Hospitals, Geneva, Switzerland
    Obesity (Silver Spring) 17:1414-9. 2009
    ..These findings emphasize the need to further investigate the potential pathogenic role of obesity and low-grade inflammation in OA and underscore the importance of obesity prevention to avoid early prosthetic replacement of the hip...
  77. doi The role of obesity, biomechanical constitution of the pelvis and contact joint stress in progression of hip osteoarthritis
    G Recnik
    Department of Orthopedic Surgery, University Hospital Maribor, Maribor, Slovenia
    Osteoarthritis Cartilage 17:879-82. 2009
    ....
  78. doi Development of a clinical prediction rule for diagnosing hip osteoarthritis in individuals with unilateral hip pain
    Thomas G Sutlive
    US Army Baylor University Dotoral Program in Physical Therapy, San Antonio, TX, USA
    J Orthop Sports Phys Ther 38:542-50. 2008
    ..Prospective cohort/predictive validity study...
  79. ncbi Evidence for a differential association of the Arg200Trp single-nucleotide polymorphism in FRZB with hip osteoarthritis and osteoporosis
    R J Lories
    Rheumatology (Oxford) 45:113-4. 2006
  80. ncbi Primary osteoarthritis of the hip: etiology and epidemiology
    F T Hoaglund
    Department of Orthopaedic Surgery, University of California at San Francisco Medical Center, 500 Parnassus Avenue (MU 320-W, San Francisco, CA 94143-0728, USA
    J Am Acad Orthop Surg 9:320-7. 2001
    ....
  81. ncbi Comparison of total hip arthroplasty performed with and without cement : a randomized trial
    Andreas Laupacis
    Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Bone Joint Surg Am 84:1823-8. 2002
    ..This study was designed to compare the fixation of a Mallory-Head total hip prosthesis with and without cement...
  82. pmc The effect of doxycycline on canine hip osteoarthritis: design of a 6-months clinical trial
    Korakot Nganvongpanit
    Bone and Joint Research Laboratory, Department of Veterinary Biosciences and Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand
    J Vet Sci 10:239-47. 2009
    ..05) at 2 and 3 months after treatment compared to pretreatment. These results showed that DOX had a positive therapeutic effect in dogs with osteoarthritis...
  83. doi Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study
    L S Lohmander
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Ann Rheum Dis 68:490-6. 2009
    To determine in a prospective population-based cohort study relationships between different measures of body mass and the incidence of severe knee and hip osteoarthritis defined as arthroplasty of knee or hip due to osteoarthritis.
  84. doi Effect of hyaluronic acid in symptomatic hip osteoarthritis: a multicenter, randomized, placebo-controlled trial
    Pascal Richette
    Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:824-30. 2009
    To evaluate the efficacy and tolerability of a single intraarticular (IA) injection of hyaluronic acid (HA) for the treatment of hip osteoarthritis (OA).
  85. pmc Characterization of individual radiographic features of hip osteoarthritis in African American and White women and men: the Johnston County Osteoarthritis Project
    Amanda E Nelson
    University of North Carolina, Chapel Hill, NC, USA
    Arthritis Care Res (Hoboken) 62:190-7. 2010
    To describe differences in radiographic features of hip osteoarthritis (OA) between African American and white men and women.
  86. doi Age at onset-dependent presentations of premature hip osteoarthritis, avascular necrosis of the femoral head, or Legg-Calvé-Perthes disease in a single family, consequent upon a p.Gly1170Ser mutation of COL2A1
    Peiqiang Su
    Second Affiliated Hospital and Center for Genome Research, Sun Yat Sen University, Guangzhou, China
    Arthritis Rheum 58:1701-6. 2008
    ....
  87. doi Cross-cultural adaptation and validation of the French version of the Hip disability and Osteoarthritis Outcome Score (HOOS) in hip osteoarthritis patients
    P Ornetti
    Dijon University Hospital, Department of Rheumatology, Dijon F 21078, France
    Osteoarthritis Cartilage 18:522-9. 2010
    ..Outcome Score (HOOS) into French and to evaluate the psychometric properties of this new version, by testing feasibility, internal consistency, construct validity, reliability and responsiveness, in patients with hip osteoarthritis (OA).
  88. ncbi A study of the Elite Plus femoral component using radiostereometric analysis
    B Derbyshire
    Wrightington Wigan and Leigh NHS Trust, Centre for Hip Surgery Wrightington Hospital, Hall Lane, Appley Bridge WN6 9EP, UK
    J Bone Joint Surg Br 89:730-5. 2007
    ..We believe that the surgical technique, particularly the use of high-viscosity cement, may have been an important factor contributing to our results...
  89. ncbi Effectiveness of nonpharmacological and nonsurgical interventions for hip osteoarthritis: an umbrella review of high-quality systematic reviews
    Rikke H Moe
    National Resource Centre for Rehabilitation in Rheumatology, Diakonhjemmet Hospital, PO Box 23 Vindern, 0319 Oslo, Norway
    Phys Ther 87:1716-27. 2007
    ..number of systematic reviews are available regarding nonpharmacological and nonsurgical interventions for hip osteoarthritis (OA)...
  90. pmc Defining incident radiographic hip osteoarthritis for epidemiologic studies in women
    Nigel K Arden
    MRC Epidemiology Resource Centre, Southampton, UK and University of Oxford, Oxford, UK
    Arthritis Rheum 60:1052-9. 2009
    To evaluate definitions of radiographic hip osteoarthritis (RHOA) for use in longitudinal epidemiologic studies of disease incidence in women.
  91. ncbi Training-induced changes in muscle CSA, muscle strength, EMG, and rate of force development in elderly subjects after long-term unilateral disuse
    Charlotte Suetta
    Institute of Sports Medicine, Bispebjerg Hospital, University of Copenhagen, 2400 NV Copenhagen, Denmark
    J Appl Physiol (1985) 97:1954-61. 2004
    ..The improvement in both muscle mass and neural function is likely to have important functional implications for elderly individuals...
  92. doi A single-group pretest posttest design using full kinetic chain manipulative therapy with rehabilitation in the treatment of 18 patients with hip osteoarthritis
    James W Brantingham
    Department of Research, Cleveland Chiropractic College Los Angeles, Los Angeles, CA 90004, USA
    J Manipulative Physiol Ther 33:445-57. 2010
    b>Hip osteoarthritis (HOA) affects 30 million Americans or more, and is a leading cause of disability, suffering, and pain. Standard treatments are minimally effective and carry significant risk and expense...
  93. doi Chiropractic management of the kinetic chain for the treatment of hip osteoarthritis: an Australian case series
    Katie de Luca
    Private Practice, 32 Elizabeth St, Parramatta NSW 2150, Australia
    J Manipulative Physiol Ther 33:474-9. 2010
    ..Previous studies support structured exercise programs and manipulation for hip osteoarthritis; however, no trials have examined treatment of the lower limb kinetic chain...
  94. ncbi Comparison of a computer based method and the classical manual method for radiographic joint space width assessment in hip osteoarthritis
    Jean Francis Maillefert
    Rene Descartes University, Institute of Rheumatology, Paris, France
    J Rheumatol 29:2592-6. 2002
    To compare the intraobserver reliability and the sensitivity to change of 2 techniques evaluating the cartilage breakdown in hip osteoarthritis (OA).
  95. ncbi Development and testing of a specific quality-of-life questionnaire for knee and hip osteoarthritis: OAKHQOL (OsteoArthritis of Knee Hip Quality Of Life)
    Anne Christine Rat
    Service d épidémiologie et évaluation clinique, EA 4003, Centre d Epidemiologie Clinique, CEC Inserm CIE6, Hopital Marin, CHU de Nancy, 2, Avenue du Marechal de Lattre de Tassigny, C O No 34, 54035 Nancy Cedex, France
    Joint Bone Spine 73:697-704. 2006
    To design a quality-of-life (QOL) instrument specific for patients with knee or hip osteoarthritis and to assess its validity and reproducibility.
  96. doi Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials
    M Fransen
    Faculty of Health Sciences, Clinical and Rehabilitation Sciences Research Group, University of Sydney, Australia
    Osteoarthritis Cartilage 18:613-20. 2010
    To determine if clinical guidelines recommending therapeutic exercise for people with hip osteoarthritis (OA) are supported by rigorous scientific evidence.
  97. pmc The effects of exercise and weight loss in overweight patients with hip osteoarthritis: design of a prospective cohort study
    Nienke Paans
    Department of Orthopaedic Surgery, University Medical Center Groningen, Groningen, The Netherlands
    BMC Musculoskelet Disord 10:24. 2009
    b>Hip osteoarthritis (OA) is recognised as a substantial source of disability, with pain and loss of function as principal symptoms...
  98. ncbi Responsiveness and clinically important differences for the WOMAC and SF-36 after hip joint replacement
    J M Quintana
    Hospital de Galdakao, Unidad de Investigacion, Barrio Labeaga s n, 48960 Galdakao, Vizcaya, Spain
    Osteoarthritis Cartilage 13:1076-83. 2005
    ....
  99. ncbi Tests for physical function of the elderly with knee and hip osteoarthritis
    Y C Lin
    Sheffield Centre of Sports Medicine, The University of Sheffield, Sheffield, England
    Scand J Med Sci Sports 11:280-6. 2001
    ..of physical function tests used to assess physical function of older patients with clinical knee and/or hip osteoarthritis (OA), and the correlation to the WOMAC Index (disease-specific questionnaire)...
  100. ncbi Physical function in men with and without hip osteoarthritis
    Merja H Arokoski
    Nilsiä Health Center, Nilsia, Finland
    Arch Phys Med Rehabil 85:574-81. 2004
    ..the subjective joint pain and function and the objective physical function of lower extremities in men with hip osteoarthritis (OA), to compare the results with those from age- and sex-matched controls, and to evaluate the ..
  101. ncbi A new marker for osteoarthritis: cross-sectional and longitudinal approach
    M Reijman
    Erasmus Medical Center, Rotterdam, The Netherlands
    Arthritis Rheum 50:2471-8. 2004
    ..To investigate the association between urinary concentrations of C-telopeptide fragments of type II collagen (CTX-II) and the prevalence and progression of radiographic osteoarthritis (OA) of the knee and hip...

Research Grants88

  1. Clinical Strategies to Reduce Osteoarthritis Disability
    Susan Murphy; Fiscal Year: 2007
    ....
  2. Periodontal Assessment in RA Study (PARAS)
    Clifton Bingham; Fiscal Year: 2007
    ....
  3. Racial Disparity in the Utilization of Joint Replacement for Osteoarthritis
    Said Ibrahim; Fiscal Year: 2007
    ..the racial/ethnic disparities in the utilization of knee/hip joint replacement in patients with knee/hip osteoarthritis (OA)...
  4. Relation of Alignment and Other Risk Factors to Knee OA
    David Felson; Fiscal Year: 2007
    ....
  5. Structural Correlates of Knee Pain
    David Felson; Fiscal Year: 2007
    ....
  6. Multi-Center Osteoarthritis Study
    Michael Nevitt; Fiscal Year: 2007
    ..abstract_text> ..
  7. Optimizing Mobility in Elders with Knee Osteoarthritis: Gait and Power Training
    Neil Segal; Fiscal Year: 2007
    ..This substantial commitment will enhance training and research productivity, enabling the candidate to become an independent investigator who will advance physical function in older adults. ..
  8. MULTICENTER OSTEOARTHRITIS STUDY (MOST)
    David Felson; Fiscal Year: 2007
    ..abstract_text> ..
  9. Relation of Alignment and Other Risk Factors to Knee OA
    DAVID TOBIN FELSON; Fiscal Year: 2010
    ....
  10. Exercise-based Motivational Interviewing for Fibromyalgia
    DENNIS CHUA ANG; Fiscal Year: 2010
    ..Furthermore, if proven efficacious, Ml could readily be applied to other chronically painful conditions (e.g. chronic back pain). ..
  11. Computer Adaptive Testing for OA Clinical Trials
    Alan Jette; Fiscal Year: 2006
    ..We expect the gains in precision and efficiency of score estimation to be superior over traditional fixed forms of assessments and transform outcomes monitoring in OA clinical trials research. ..
  12. Efficacy of a Post-Rehabilitation Exercise Intervention
    ALAN MAURICE JETTE; Fiscal Year: 2010
    ..This low-cost program could be used by many people after hip fracture, and could potentially help to reduce the number of people who need to move to a nursing home or need long term home help. ..
  13. Efficacy of a Post-Rehabilitation Exercise Intervention
    Alan Jette; Fiscal Year: 2007
    ..This low-cost program could be used by many people after hip fracture, and could potentially help to reduce the number of people who need to move to a nursing home or need long term home help. ..
  14. RHEUMATOLOGY TRAINING GRANT
    David Felson; Fiscal Year: 2007
    ..The faculty provide a strong and experienced approach and will devote their talents to the training grant. ..
  15. ETHNIC DISPARITY IN THE USE OF JOINT ARTHROPLASTY
    DENNIS ANG; Fiscal Year: 2006
    ..The proposed study is significant because modifiable factors identified at the patient-PCP level may be amenable to educational or behavioral intervention which could eradicate ethnic disparity. ..
  16. THE FRAMINGHAM OSTEOARTHRITIS STUDY
    David Felson; Fiscal Year: 2005
    ....
  17. CLINICAL RESEARCH TRAINING PROGRAM
    David Felson; Fiscal Year: 2004
    ..Fourth, we will integrate residents in training into the CREST program to develop an interest in clinical research at an early stage of training. ..
  18. ETHNIC DISPARITY IN THE USE OF JOINT ARTHROPLASTY
    DENNIS ANG; Fiscal Year: 2003
    ..The proposed study is significant because modifiable factors identified at the patient-PCP level may be amenable to educational or behavioral intervention which could eradicate ethnic disparity. ..
  19. ETHNIC DISPARITY IN THE USE OF JOINT ARTHROPLASTY
    DENNIS ANG; Fiscal Year: 2007
    ..The Program Director, Munro Peacock, M.D., was appointed in July 1987. The GCRC was ..
  20. Laxity and Malalignment in a Large Cohort Study of OA
    Michael Nevitt; Fiscal Year: 2006
    ..abstract_text> ..
  21. Innovative Methods for Function and Disability Assessment
    Alan Jette; Fiscal Year: 2007
    ..The public health research and clinical communities would be the likely markets interested in the CAT technology that would be developed and evaluated in this STTR. ..
  22. Relation of Alignment and Other Risk Factors to Knee OA
    David Felson; Fiscal Year: 2009
    ....
  23. MECHANISMS OF IMPLANT PARTICLE-INDUCED OSTEOCLASTOGENESI
    John Clohisy; Fiscal Year: 2002
    ..Our aims are: 1) to determine the mechanism(s) by which PMMA particles induce NF-kB activation in osteoclast precursor cells and 2) to determine the effect of blocking NF-kB activation on PMMA-induced osteoclastogenesis in vitro. ..
  24. SELF CARE--COMPARISION OF AFRICAN AMERICANS AND WHITES
    Myrna Silverman; Fiscal Year: 2003
    ..The research will be guided by a preliminary model informed by theoretical perspectives directed at the individual's decision making and their socio-cultural context. ..
  25. Trial of Asthma Patient Education in the Emergency Room
    Carol Mancuso; Fiscal Year: 2009
    ..Other long-term objectives are to use the program as a basis for similar programs for children, adolescents and their caregivers in the ED, primary care, and school settings. ..
  26. Exercise-based Motivational Interviewing for Fibromyalgia
    DENNIS ANG; Fiscal Year: 2007
    ..Furthermore, if proven efficacious, Ml could readily be applied to other chronically painful conditions (e.g. chronic back pain). ..
  27. Trial of Asthma Patient Education in the Emergency Room
    Carol Mancuso; Fiscal Year: 2007
    ..Other long-term objectives are to use the program as a basis for similar programs for children, adolescents and their caregivers in the ED, primary care, and school settings. ..
  28. Benefits and Burdens of Screening Oldest-old Women: the Case of Mammography
    MARA SCHONBERG; Fiscal Year: 2007
    ..It will also further her long-term career goal to become a skilled and established independent investigator in the area of disease prevention and health promotion for the oldest-old. ..
  29. NIAMS Multidisciplinary Clin Res Ctr: Rheumatic Diseases
    Joanne Jordan; Fiscal Year: 2007
    ..An Administrative Core will provide financial and scientific oversight and direction to the Center and will be composed of a Director, an Associate Director, an Executive Committee, and support staff. ..
  30. NIAMS Multidisciplinary Clin Res Ctr: Rheumatic Diseases
    Joanne Jordan; Fiscal Year: 2006
    ..An Administrative Core will provide financial and scientific oversight and direction to the Center and will be composed of a Director, an Associate Director, an Executive Committee, and support staff. ..
  31. Mammography Screening Decisions in the Elderly
    MARA SCHONBERG; Fiscal Year: 2005
    ..This is the first study to explore very elderly women's approach to decisions about screening mammography. ..
  32. Factors influencing the evolution of knee osteoarthritis
    Najia Shakoor; Fiscal Year: 2007
    ..abstract_text> ..
  33. ARTHRITIS AND IMMUNOLOGY
    Joanne Jordan; Fiscal Year: 2007
    ..The majority of pre- (24 of 24, 100%) and post-doctoral (39 of 44, 89%) trainees in this program over the last 10 years are currently engaged in academic endeavors as trainees, university faculty or industry researchers. ..