Research Topics
| myofascial pain syndromesSummarySummary: Muscular pain in numerous body regions that can be reproduced by pressure on trigger points, localized hardenings in skeletal muscle tissue. Pain is referred to a location distant from the trigger points. A prime example is the TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME. Top Publications
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Publications
Superficial dry needling and active stretching in the treatment of myofascial pain--a randomised controlled trialJanet Edwards
Acupunct Med 21:80-6. 2003..Stretching without prior deactivation may increase TrP sensitivity...
Pain relief by electrostimulation of myofascial trigger points: peripheral or central mechanisms?Till Sprenger
Clin J Pain 23:638-9. 2007
Central representation of hyperalgesia from myofascial trigger pointDavid M Niddam
Brain Research Center, National Yang Ming University, Taipei, Taiwan
Neuroimage 39:1299-306. 2008..We speculate that suppressed hippocampal activity might reflect stress-related changes in relation to chronic pain as an effective physical and emotional stressor...
Biochemicals associated with pain and inflammation are elevated in sites near to and remote from active myofascial trigger pointsJay P Shah
Rehabilitation Medicine Department, National Institutes of Health, Clinical Center, Bethesda, MD 20892, USA
Arch Phys Med Rehabil 89:16-23. 2008..To investigate the biochemical milieu of the upper trapezius muscle in subjects with active, latent, or absent myofascial trigger points (MTPs) and to contrast this with that of the noninvolved gastrocnemius muscle...
Myofascial trigger points and sensitization: an updated pain model for tension-type headacheC Fernández-de-Las-Peñas
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos, Madrid, Spain
Cephalalgia 27:383-93. 2007..In this updated pain model, TrPs would be the primary hyperalgesic zones responsible for the development of central sensitization in CTTH...
Coexistence of fibromyalgia, temporomandibular disorder, and masticatory myofascial pain syndromesBerrin Leblebici
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Baskent University, Ankara, Turkey
Rheumatol Int 27:541-4. 2007..Our results indicate that coexistence of FM and TMD with MMP is high. Pain and tenderness in the masticatory muscles appear to be an important element in FM, so in some patients it may be the leading complaint...
Test-retest reliability of myofascial trigger point detection in patients with rotator cuff tendonitisAbdullah M Al-Shenqiti
Centre for Rehabilitation Science, University of Manchester, UK
Clin Rehabil 19:482-7. 2005..Referred pain and local twitch response reliability varied depending on the muscle being studied...
Review of enigmatic MTrPs as a common cause of enigmatic musculoskeletal pain and dysfunctionDavid G Simons
Department of Rehabilitation Medicine, Emory University, 3176 Monticello Street, Atlanta, GA 20014 3535, USA
J Electromyogr Kinesiol 14:95-107. 2004..Specific research needs are noted. MTrPs are treatable and they deserve increased attention and consideration by research investigators and clinicians...
The impact of latent trigger points on regional muscle functionKaren R Lucas
RMIT University, Clinical Neuroscience Research Group, School of Health Sciences, PO Box 71, Bundoora, Melbourne, Victoria, Australia
Curr Pain Headache Rep 12:344-9. 2008..This article offers suggestions as to the mechanisms via which LTrP-related pathophysiology may explain the clinical examination findings associated with LTrP-containing and functionally related muscles...
Myofascial trigger point development from visual and postural stressors during computer workD Treaster
The Biodynamics Laboratory, The Ohio State University, 1971 Neil Ave, 210 Baker Systems, Columbus, OH 43210, USA
J Electromyogr Kinesiol 16:115-24. 2006..5 cycles). These significant differences between conditions were found for the right trapezius but not for the left. The findings suggest that high visual stress may be involved in the development of the myofascial pain response...
Ability of magnetic resonance elastography to assess taut bandsQingshan Chen
Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Clin Biomech (Bristol, Avon) 23:623-9. 2008..This study explores the ability of magnetic resonance elastography to localize and investigate the mechanical properties of myofascial taut bands on the basis of their effects on shear wave propagation...
Urologic myofascial pain syndromesRagi Doggweiler-Wiygul
Department of Urology, University of Tennessee, 1211 Union Avenue, Suite 340, Memphis, TN 38104, USA
Curr Pain Headache Rep 8:445-51. 2004..The referred pain syndrome can long outlast the initial event, making diagnosis difficult...
Treatment of myofascial trigger points in common shoulder disorders by physical therapy: a randomized controlled trial [ISRCTN75722066]Carel Bron
Research Centre for Allied Health Sciences, Centre for Quality of Care Research, Radboud University Medical Centre, Nijmegen, The Netherlands
BMC Musculoskelet Disord 8:107. 2007..In addition we investigate the recurrence rate during a one-year-follow-up period...
Chronic shoulder pain of myofascial origin: a randomized clinical trial using ischemic compression therapyGuy Hains
Private Practice, Trois Rivieres, Côte Richelieu, Trois Rivieres, Quebec, Canada
J Manipulative Physiol Ther 33:362-9. 2010..The aim of this clinical trial was to evaluate the effect of 15 myofascial therapy treatments using ischemic compression on shoulder trigger points in patients with chronic shoulder pain...
Evidence of neuroaxonal degeneration in myofascial pain syndrome: a study of neuromuscular jitter by axonal microstimulationChein Wei Chang
Department of Physical Medicine and Rehabilitation, National Taiwan University College of Medicine and Hospital, No 1, Chang Te St, Taipei 100, Taiwan
Eur J Pain 12:1026-30. 2008..The mechanism of MPS is possibly implicated with the degeneration of motor neurons...
Myofascial pain syndromes and their evaluationRobert Bennett
Oregon Health and Science University, SNORD 219, Portland, OR 97239 2941, USA
Best Pract Res Clin Rheumatol 21:427-45. 2007..Although myofascial pain syndromes have been described in the medical literature for about the last 100 years, it is only recently that ..
Treatment of myofascial pain syndromeChang Zern Hong
Department of Physical Therapy, Hungkuang University, Shalu, Taichung, Taiwan
Curr Pain Headache Rep 10:345-9. 2006..It is also important to eliminate any perpetuating factors and provide adequate education and home programs to patients so that recurrent or chronic pain can be avoided...
Immediate effect of ultrasound and ischemic compression techniques for the treatment of trapezius latent myofascial trigger points in healthy subjects: a randomized controlled studyF Javier Montañez Aguilera
Department of Physical Therapy, Universidad CEU Cardenal Herrera, Valencia, Spain
J Manipulative Physiol Ther 32:515-20. 2009..The purpose of this study was to determine immediate effects of ischemic compression (IC) and ultrasound (US) for the treatment of myofascial trigger points (MTrPs) in the trapezius muscle...
Myofascial pain disorders: theory to therapyAnthony H Wheeler
Pain and Orthopedic Neurology, Charlotte Spine Center, Charlotte, North Carolina 28207, USA
Drugs 64:45-62. 2004..Chronic myofascial pain is usually a product of both physical and psychosocial influences that complicate convalescence...
Acupuncture and dry needling in the management of myofascial trigger point pain: a systematic review and meta-analysis of randomised controlled trialsElizabeth A Tough
Primary Care, Peninsula Medical School, Universities of Exeter and Plymouth, ITTC Building, Tamar Science Park, Plymouth PL6 8BX, UK
Eur J Pain 13:3-10. 2009..However, the limited sample size and poor quality of these studies highlights and supports the need for large scale, good quality placebo controlled trials in this area...
Regional myofascial pain: diagnosis and managementMike Cummings
Best Pract Res Clin Rheumatol 21:367-87. 2007..The clinical evidence for and against the common therapeutic interventions used in the management of myofascial pain is reviewed in detail and some tentative conclusions are reached with respect to needling therapies...
Reliability of physical examination for diagnosis of myofascial trigger points: a systematic review of the literatureNicholas Lucas
School of Biomedical and Health Sciences, University of Western Sydney, Auckland, New Zealand
Clin J Pain 25:80-9. 2009..Trigger points are promoted as an important cause of musculoskeletal pain. There is no accepted reference standard for the diagnosis of trigger points, and data on the reliability of physical examination for trigger points are conflicting...
An expansion of Simons' integrated hypothesis of trigger point formationRobert D Gerwin
Johns Hopkins University Pain and Rehabilitation Medicine, Bethesda, MD 20814 2432, USA
Curr Pain Headache Rep 8:468-75. 2004..We propose an expansion of this hypothesis to account for new experimental data and established muscle pathophysiology...
Myofascial trigger points, neck mobility and forward head posture in unilateral migraineC Fernández-de-Las-Peñas
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos, and Department of Neurology, Fundacion Hospital Alcorcon, Madrid, Spain
Cephalalgia 26:1061-70. 2006..Active TrPs located ipsilateral to migraine headaches might be a contributing factor in the initiation or perpetuation of migraine...
Needle electromyographic activity of myofascial trigger points and control sites in equine cleidobrachialis muscle--an observational studyJoanne Macgregor
Equine Veterinary Clinic, Greyfriars Farm, Puttenham, Guildford, UK
Acupunct Med 24:61-70. 2006..The important differences from findings in human studies are that referred pain patterns and the reproduction of pain profile cannot be determined in animals...
Electrophysiological assessment of acupuncture pointsMu-Jung Kao
China Medical University and the Department of Physical Medicine and Rehabilitation, Taipei City Hospital, Taipei, Taiwan
Am J Phys Med Rehabil 85:443-8. 2006..This study provides additional support to the hypothesis that some AcPs are also myofascial trigger points...
Myofascial trigger pointsElizabeth Demers Lavelle
Department of Anesthesiology, Albany Medical Center, 43 New Scotland Avenue, Albany, NY 12208, USA
Anesthesiol Clin 25:841-51, vii-iii. 2007..The etiology, pathophysiology, and treatment of myofascial trigger points are addressed in this article...
A review of myofascial pain and fibromyalgia--factors that promote their persistenceRobert D Gerwin
Acupunct Med 23:121-34. 2005..Sometimes, correction of an underlying cause of myalgia is all that is needed to resolve the condition...
Needling therapies in the management of myofascial trigger point pain: a systematic reviewT M Cummings
British Medical Acupuncture Society, London, England
Arch Phys Med Rehabil 82:986-92. 2001..To establish whether there is evidence for or against the efficacy of needling as a treatment approach for myofascial trigger point pain...
Endplate potentials are common to midfiber myofacial trigger pointsDavid G Simons
Department of Physical Medicine and Rehabilitation, University of California-Irvine, USA
Am J Phys Med Rehabil 81:212-22. 2002..Endplate noise seems to be characteristic of, but is not restricted to, the region of a myofascial trigger point...
Interventional approaches to the management of myofascial pain syndromeC M Criscuolo
Division of Pain Medicine, Department of Anesthesiology, University of Nebraska Medical Center, 984455 Nebraska Medical Center, Omaha, NE 68198 4455, USA
Curr Pain Headache Rep 5:407-11. 2001Interventional therapies are a valuable addition to our armamentarium when treating myofascial pain syndromes. When combined with other therapies, interventional techniques can be an effective adjunct in the multidisciplinary management ..
Acupuncture needling versus lidocaine injection of trigger points in myofascial pain syndrome in elderly patients--a randomised trialHyuk Ga
Department of Family Medicine, Inha University College of Medicine, Incheon, Korea
Acupunct Med 25:130-6. 2007..To compare the efficacy of acupuncture needling and 0.5% lidocaine injection of trigger points in myofascial pain syndrome of elderly patients...
Effectiveness of a home program of ischemic pressure followed by sustained stretch for treatment of myofascial trigger pointsW P Hanten
School of Physical Therapy, Texas Woman s University, 1130 MD Anderson Blvd, Houston, TX 77030, USA
Phys Ther 80:997-1003. 2000..The purpose of this study was to determine the effectiveness of a home program of ischemic pressure followed by sustained stretching for the treatment of myofascial TPs...
Botulinum toxin A for myofascial trigger point injection: a qualitative systematic reviewKok Yuen Ho
Pain Management Services, Department of Anaesthesia and Surgical Intensive Care, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
Eur J Pain 11:519-27. 2007..The current evidence does not support the use of BTA injection in trigger points for myofascial pain. The data is limited and clinically heterogeneous...
Clinical precision of myofascial trigger point location in the trapezius muscleV M Sciotti
New York Chiropractic College, Seneca Falls, NY 13148, USA
Pain 93:259-66. 2001....
Management of myofascial trigger point painPeter Baldry
Acupunct Med 20:2-10. 2002..It is also important that the practitioner excludes certain biochemical disorders...
Signs and symptoms of the myofascial pain syndrome: a national survey of pain management providersR N Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Illinois 60611, USA
Clin J Pain 16:64-72. 2000..The goal of this study was to assess clinical consensus regarding whether myofascial pain syndrome (MPS) is a legitimate and distinct diagnosis as well as the signs and symptoms characterizing MPS...
Myofascial trigger points show spontaneous needle EMG activityD R Hubbard
Department of Neurosciences, University of California, San Diego
Spine (Phila Pa 1976) 18:1803-7. 1993..Mean EMG amplitude in the patient groups was significantly greater than in normals. The authors hypothesize that TrPs are caused by sympathetically activated intrafusal contractions...
The myofascial trigger point region: correlation between the degree of irritability and the prevalence of endplate noiseTa Shen Kuan
Department of Physical Medicine and Rehabilitation, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Am J Phys Med Rehabil 86:183-9. 2007..This study was designed to investigate the correlation between the irritability of the myofascial trigger point (MTrP) and the prevalence of endplate noise (EPN) in the MTrP region of human skeletal muscle...
Myofascial pain--an overviewEng Ching Yap
Department of Rehabilitation Medicine, Tan Tock Seng Hospital, Singapore
Ann Acad Med Singapore 36:43-8. 2007..Early diagnosis and management may also help reduce psychosocial complications and financial burden of chronic pain syndrome...
Dry needling of trigger points with and without paraspinal needling in myofascial pain syndromes in elderly patientsHyuk Ga
Department of Family Medicine, Inha University College of Medicine, Incheon, South Korea
J Altern Complement Med 13:617-24. 2007..To compare the efficacies of dry needling of trigger points (TrPs) with and without paraspinal needling in myofascial pain syndrome of elderly patients...
Lesions of rat skeletal muscle after local block of acetylcholinesterase and neuromuscular stimulationS Mense
Department of Anatomy and Cell Biology III, Heidelberg University, D 69 120 Heidelberg, Germany
J Appl Physiol 94:2494-501. 2003....
Effectiveness of ropivacaine trigger points inactivation in the prophylactic management of patients with severe migraineJuan M Garcia Leiva
Instituto de Neurociencias, Universidad de Granada, Granada, Spain
Pain Med 8:65-70. 2007..Tenderness and referred pain have been described in migraine and involved in its pathogenesis. The present study was performed to evaluate the prophylactic effectiveness of ropivacaine injections during a 12-week period...
Fibromyalgia syndrome: presentation, diagnosis, differential diagnosis, and vulnerabilityI Jon Russell
University Clinical Research Center, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
CNS Spectr 13:6-11. 2008..Existing data suggest that some individuals with FMS may have a dysregulated physiological stress response system that predates the onset of symptoms...
Effects of dry needling at tender points for neck pain (Japanese: katakori): near-infrared spectroscopy for monitoring muscular oxygenation of the trapeziusShizuo Jimbo
Department of Orthopaedic Surgery, Rishiri Island Central Hospital, Hokkaido, Japan
J Orthop Sci 13:101-6. 2008..The purpose of this study was to investigate the effects of tender point dry needling to the trapezius muscles and the resultant changes in muscular hemodynamics...
Characteristics of electrical activity in trapezius muscles with myofascial painJin Woo Chung
Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea
Clin Neurophysiol 117:2459-66. 2006..CONCLUSIONS: We suggest that the electrical activity arises from a localized zone and is stable over time. SIGNIFICANCE: Our data provide evidence for the reliability and validity of the electrical activity from myofascial tender areas...
The local and referred pain from myofascial trigger points in the temporalis muscle contributes to pain profile in chronic tension-type headacheCésar Fernández-de-Las-Peñas
Department of Physical Therapy of Universidad Rey Juan Carlos, Madrid, Spain
Clin J Pain 23:786-92. 2007..To assess the local and referred pain areas and pain characteristics evoked from temporalis muscle trigger points (TrPs) in chronic tension-type headache (CTTH)...
Central modulation of pain evoked from myofascial trigger pointDavid M Niddam
Laboratory of Integrated Brain Research, Department of Medical Research and Education, Taipei Veterans General Hospital, No 201 Section 2 Shih Pai Road, Taipei 112, Taiwan
Clin J Pain 23:440-8. 2007..We hypothesized that intervention induces pain inhibition via the periaqueductal gray (PAG)...
A double-blind, controlled study of botulinum toxin A in chronic myofascial painE Qerama
Danish Pain Research Center, Aarhus University Hospital, Denmark
Neurology 67:241-5. 2006..The present double-blind, randomized, placebo-controlled, parallel clinical trial studied the effect of BTXA on pain from muscle trigger points and on EMG activity at rest and during voluntary contraction...
A psycho-educational video used in the emergency department provides effective treatment for whiplash injuriesAli Oliveira
California School of Professional Psychology at Alliant International University, San Diego, CA, USA
Spine 31:1652-7. 2006..05, all). For example, 4% of video patients were using narcotics at 6 month post ED visit compared with 36% of controls. The brief psycho-educational video had a profound effect on subsequent pain and medical utilization...
Comparison of clinical and evoked pain measures in fibromyalgiaRichard E Harris
Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48106, USA
J Pain 7:521-7. 2006..Pressure pain testing that applies stimuli in a random order is associated with improvements in clinical pain, but this association was not stronger than other experimental techniques...
Referred pain from trapezius muscle trigger points shares similar characteristics with chronic tension type headacheCésar Fernández-de-Las-Peñas
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation of Universidad Rey Juan Carlos, Alcorcon, Madrid, Spain
Eur J Pain 11:475-82. 2007..Our results suggest that spatial summation of perceived pain and mechanical pain sensitivity exists in CTTH patients...
Myofascial trigger points are very prevalent in patients with chronic tension-type headache: a double-blinded controlled studyChristian Couppe
Department of Neurology, Danish Headache Center, University of Copenhagen, Glostrup Hospital, Denmark
Clin J Pain 23:23-7. 2007b>Myofascial pain syndromes due to trigger points (TrPs) are clinical entities, but more evidence is needed to evaluate TrP palpation...
Prognostic factors for neuroreflexotherapy in the treatment of subacute and chronic neck and back pain: a study of predictors of clinical outcome in routine practice of the Spanish National Health ServiceFrancisco Kovacs
Scientific Department, Fundacion Kovacs, Madrid, Spain
Spine (Phila Pa 1976) 32:1621-8. 2007..Prospective cohort follow-up study...
Future perspectives: pathogenesis of chronic muscle painRoland Staud
Department of Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0221, USA
Best Pract Res Clin Rheumatol 21:581-96. 2007....
Increased levels of interstitial potassium but normal levels of muscle IL-6 and LDH in patients with trapezius myalgiaLars Rosendal
National Institute of Occupational Health, Copenhagen, Denmark
Pain 119:201-9. 2005..This finding could be causally related to myalgia or secondary to pain due to deconditioned muscle or altered muscle activity pattern...
Comparison between newer local anesthetics for myofascial pain syndrome managementA Th Zaralidou
Department of Anesthesiology, Pain Clinic, AHEPA University Hospital, Thessaloniki, Greece
Methods Find Exp Clin Pharmacol 29:353-7. 2007b>Myofascial pain syndromes are characterized by the presence of painful loci within muscles, tendons or ligaments, called trigger points. Infiltration of these points with local anesthetics is often used as a treatment modality...
Topographical mapping and mechanical pain sensitivity of myofascial trigger points in the infraspinatus muscleHong You Ge
Centre for Sensory Motor Interaction SMI, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7 D 3, DK 9220 Aalborg, Denmark
Eur J Pain 12:859-65. 2008..To screen for the presence of latent and active myofascial trigger points (MTrPs) in patients with unilateral shoulder and arm pain and perform topographical mapping of mechanical pain sensitivity bilaterally in the infraspinatus muscles...
Electromyographically guided trigger point injections in the cervicothoracic musculature of obese patients: a new and unreported techniqueKenneth P Botwin
Deuk Spine Institute, Titusville, FL, USA
Pain Physician 10:753-6. 2007..In the cervicothoracic spine, a misguided or misplaced injection can result in a pneumothorax. Here, we review an electromyographically guided trigger point injection technique to avoid this potential pitfall...
Myofascial trigger points, neck mobility, and forward head posture in episodic tension-type headacheCesar Fernandez de Las Penas
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation of Universidad Rey Juan Carlos, Alcorcon, Madrid, Spain
Headache 47:662-72. 2007..In addition, we assess the relationship between these muscle TrPs, FHP, neck mobility, and several clinical variables concerning the intensity and the temporal profile of headache...
Prevalence of and referred pain from myofascial trigger points in the forearm muscles in patients with lateral epicondylalgiaJosué Fernández-Carnero
Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcon, Madrid, Spain
Clin J Pain 23:353-60. 2007....
[Myofascial pain syndrome]Peter Reilich
Friedrich-Baur-Institut an der Neurologischen Klinik,
MMW Fortschr Med 149:44-6. 2007
Office management of chronic pain in the elderlyDebra K Weiner
Division of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Penn, USA
Am J Med 120:306-15. 2007..While common, chronic pain is not a normal part of aging, and it should be treated with an emphasis on improved physical function and quality of life...
Cervical pain and headache in patients with facial asymmetries: the effect of orthognathic surgical correctionA Corbacelli
Department of Surgical Sciences, Maxillofacial Surgery Institute, University of L Aquila, L Aquila, Italy
Minerva Anestesiol 73:281-9. 2007..The aim of the study was to evaluate the influence of surgical orthognathic correction of facial asymmetries on the intensity of cervicobrachial pain and headache in the short and long term...
Miniscalpel-needle versus triggerpoint injection for cervical myofascial pain syndrome: a randomized comparative trialChunxiao Wang
J Altern Complement Med 13:14-6. 2007
Chronic widespread musculoskeletal pain - a comparison of those who meet criteria for fibromyalgia and those who do notLars Coster
Section of Rheumatology, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
Eur J Pain 12:600-10. 2008..Similar coping strategies were found. Chronic widespread pain without widespread allodynia to pressure pain was found in 4.5% in the population and fibromyalgia in 2.5%...
Induction of muscle cramps by nociceptive stimulation of latent myofascial trigger pointsHong You Ge
Laboratory for Experimental Pain Research, Center for Sensory Motor Interaction SMI, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7 D 3, 9220, Aalborg, Denmark
Exp Brain Res 187:623-9. 2008..These results suggest that latent MTrPs could be involved in the genesis of muscle cramps. Focal increase in nociceptive sensitivity at MTrPs constitutes one of the mechanisms underlying muscle cramps...
Effectiveness and cost-effectiveness analysis of neuroreflexotherapy for subacute and chronic low back pain in routine general practice: a cluster randomized, controlled trialFrancisco M Kovacs
Departamento Cientifico, Fundacion Kovacs, Unidad de Investigacion, Gerencia de Atención Primaria, Insalud Balears, Palma de Mallorca, Spain
Spine (Phila Pa 1976) 27:1149-59. 2002..A cluster randomized, controlled trial was performed...
Bilateral myofascial trigger points in the forearm muscles in patients with chronic unilateral lateral epicondylalgia: a blinded, controlled studyJosué Fernández-Carnero
Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcon, Madrid, Spain
Clin J Pain 24:802-7. 2008....
Effect of increased sympathetic activity on electrical activity from myofascial painful areasJin Woo Chung
Department of Oral Medicine and Oral Diagnosis, College of Dentistry, Seoul National University, Seoul, Korea
Am J Phys Med Rehabil 83:842-50. 2004..CONCLUSION: The significant electromyographic increase from painful areas and no significant increase from control channels are consistent with the view that sympathetic neural outflow increases painful-area electrical activity...
Clinical study of chronic pain in hereditary myopathiesThierry Delorme
Centre d Evaluation et de Traitement de la Douleur, Hopital Saint Antoine, 184 rue du Faubourg, 75102 Saint Antoine, Paris, France
Eur J Pain 8:55-61. 2004..For 42 patients (91%) the principal cause of the pain was of muscular origin, with frequent features of myofascial pain syndromes (MPS, 50%) and fibromyalgia (FMS, 26%). Pain was the major complaint for 6.3% of the patients...
Predictors of clinical pain intensity in patients with fibromyalgia syndromeRoland Staud
Division of Rheumatology and Clinical Immunology, University of Florida, PO Box 100221, Gainesville, FL 32610, USA
Curr Rheumatol Rep 6:281-6. 2004..Therefore, wind-up after-sensations, tender point count, and negative affect not only seem to represent relevant pain mechanisms but also strongly emphasize their importance for fibromyalgia syndrome pain...
High-power pain threshold ultrasound technique in the treatment of active myofascial trigger points: a randomized, double-blind, case-control studyJavid Majlesi
Istanbul Hospital, Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
Arch Phys Med Rehabil 85:833-6. 2004....
A proposed experimental model of myofascial trigger points in human muscle after slow eccentric exerciseKazunori Itoh
Meiji University of Oriental Medicine, Kyoto, Japan
Acupunct Med 22:2-12; discussion 12-3. 2004..The sensitised nociceptors at the fascia of the palpable band might be a possible candidate for the localised tender region...
Botulinum toxin type B in piriformis syndromeAmy M Lang
Department of Rehabilitation Medicine, Emory University School of Medicine and Hospitals, Atlanta, Georgia, USA
Am J Phys Med Rehabil 83:198-202. 2004..CONCLUSIONS: Findings suggest the possibility that botulinum toxin type B may be of potential benefit in the treatment of pain attributed to piriformis syndrome...
[Chronic widespread pain and tender points in low back pain: a population-based study]A Hüppe
Institut für Sozialmedizin, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Beckergrube 43 47, 23552 Lübeck, Germany
Z Rheumatol 63:76-83. 2004..We additionally studied the association of the severity of back pain and both chronic widespread musculoskeletal pain and active tender points...
Evoked pain in the motor endplate region of the brachial biceps muscle: an experimental studyErisela Qerama
Danish Pain Research Center, Aarhus University Hospital, Building 1A, Noerrebrogade 44, DK 8000 Aarhus, Denmark
Muscle Nerve 29:393-400. 2004..A higher density of muscle nociceptors in the vicinity of the motor endplate region may account for the observed differences in pain. These findings may have clinical implications for the treatment of musculoskeletal pain conditions...
Opioid-insensitive hypoalgesia to mechanical stimuli at sites ipsilateral and contralateral to experimental muscle pain in human volunteersThomas Graven-Nielsen
Center for Sensory Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7D 3, 9220 Aalborg E, Denmark
Exp Brain Res 146:213-22. 2002..The deep peroneal nerve specifically innervates both the TA muscle and the only site of hyperalgesia indicating spatial summation of afferent activity from these structures...
Use of botulinum toxin in the treatment of chronic myofascial painJ De Andres
Multidisciplinary Pain Management Center, Department of Anesthesia, Valencia University General Hospital, Spain
Clin J Pain 19:269-75. 2003..Previous studies have suggested the usefulness of botulinum toxin A (BTX-A) in the treatment of MPS since it is capable of controlling muscular spasms, as well as other alternative mechanisms of action...
Induction of prolonged tenderness in patients with tension-type headache by means of a new experimental model of myofascial painH Mørk
Department of Neurology, Copenhagen Headache Center, University of Copenhagen, Glostrup Hospital, Glostrup, Copenhagen, Denmark
Eur J Neurol 10:249-56. 2003..The present results suggest an increased excitability of peripheral muscle afferents in TTH...
Myopain 2004: Sixth World Congress on myofascial pain and fibromyalgia. July 18-22, 2004, Munich, GermanySandro Palla
J Orofac Pain 19:89-90. 2005
Contribution of myofascial trigger points to migraine symptomsMaria Adele Giamberardino
Headache Center, Department of Medicine and Science of Aging, G D Annunzio University Ce S I, G d Annunzio Foundation, Chieti, Italy
J Pain 8:869-78. 2007..These results suggest that migraine pain is often contributed to by myofascial inputs that enhance the level of central neuronal excitability...
Can classical acupuncture points and trigger points be compared in the treatment of pain disorders? Birch's analysis revisitedPeter T Dorsher
Department of Physical Medicine and Rehabilitation, Mayo Clinic, Jacksonville, Florida 32224, USA
J Altern Complement Med 14:353-9. 2008..Moreover, Birch concluded that no more than 40% of the acupuncture points examined by Melzack et al. correlated clinically for the treatment of pain (correlation was more like 18%-19%)...
Long-term follow-up of trigger point injections for abdominal wall painJose Nazareno
Department of Medicine, The University of Western Ontario, London Health Sciences Centre, Canada
Can J Gastroenterol 19:561-5. 2005..025) were statistically significant predictors of a positive response to TPI. CONCLUSIONS: This study demonstrates that TPI, in patients who meet criteria for AWP, are effective over the long term...
On the impossibility of trigger point-acupoint equivalence: a commentary on Peter Dorsher's analysisStephen Birch
J Altern Complement Med 14:343-5. 2008
Referred pain and hyperalgesia in human tendon and muscle belly tissueWilliam Gibson
Laboratory for Experimental Pain Research, Center for Sensory-Motor Interaction (SMI, Department of Health Science and Technology, Aalborg University, Denmark
Pain 120:113-23. 2006..Furthermore, there may be site specific central changes reflected by the differences in the results regarding sensitivity and summation over time...
Are tender point injections beneficial: the role of tonic nociception in fibromyalgiaRoland Staud
Division of Rheumatology and Clinical Immunology, University of Florida, PO Box 100221, Gainesville, FL 32610 0221, USA
Curr Pharm Des 12:23-7. 2006..Thus interventions aimed at reducing local FM pain seem to be effective but need to focus less on tender points but more on trigger points (TrP) and other body areas of heightened pain and inflammation...
Referred pain pattern of the pronator quadratus muscleMiriam Hwang
Department of Rehabilitation Medicine, Korea University College of Medicine, 516 Gozan Dong, Ansan City, Kyonggi Province 425-707, South Korea
Pain 116:238-42. 2005..Thus, myofascial pain of the PQ should be considered as a possible cause of pain in the medial forearm and hand, especially when no other neurological abnormalities are present...
Hyperbaric oxygen therapy in chronic pain managementSenol Yildiz
Department of Undersea and Hyperbaric Medicine, Gulhane Military Medical Academy Haydarpasa Training Hospital, 34668 Kadikoy, Istanbul, Turkey
Curr Pain Headache Rep 10:95-100. 2006..Another problem regarding HBO is the scarcity of centers administering it. Further research is required focusing on the optimal treatment protocol, the cost/benefit ratio, and the safety of HBO in chronic pain management...
Increased muscular and cutaneous pain sensitivity in cephalic region in patients with chronic tension-type headacheS Ashina
Danish Headache Center and Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Copenhagen, Denmark
Eur J Neurol 12:543-9. 2005..Increased sensitivity in nociceptive pathways from cephalic region may be of importance in the pathophysiology of chronic tension type headache...
Can the neuropathic pain scale discriminate between non-neuropathic and neuropathic pain?David A Fishbain
Department of Psychiatry, University of Miami, Miami, Florida, USA
Pain Med 9:149-60. 2008....
Botulinum neurotoxins in the treatment of refractory painBahman Jabbari
Department of Neurology, Yale University, New Haven, CT 06520, USA
Nat Clin Pract Neurol 4:676-85. 2008..include cervical dystonia, pelvic pain, low back pain, plantar fasciitis, postsurgical painful spasms, myofascial pain syndromes, migraine, and chronic daily headaches...
Vaginal pressure-pain thresholds: initial validation and reliability assessment in healthy womenFrank F Tu
Department of Obstetrics and Gynecology Feinberg School of Medicine and Evanston Northwestern Healthcare, Evanston, IL 60201, USA
Clin J Pain 24:45-50. 2008..To develop psychophysical measures to facilitate diagnosis of pelvic floor myofascial pain syndromes, this pilot was designed to preliminarily test the feasibility, reliability, and validity of pressure-..
[Evidence for laser acupuncture in cases of orthopedic diseases : a systematic review]B K Schüller
Institut für Forschung in der Operativen Medizin IFOM, Fakultät für Medizin der Universität Witten Herdecke, Ostmerheimer Str 200, 51109, Koln, Deutschland
Schmerz 22:9-15. 2008..The aim of this review is to evaluate the evidence for laser acupuncture in selected orthopaedic diseases...
Effects of treatment of peripheral pain generators in fibromyalgia patientsGiannapia Affaitati
Pathophysiology of Pain Laboratory, Ce S I, G d Annunzio Foundation, Department of Medicine and Science of Aging, Chieti University, via Carlo de Tocco n 3, Chieti, Italy
Eur J Pain 15:61-9. 2011..Female patients with (1) FS+myofascial pain syndromes from trigger points (n=68), or (2) FS+joint pain (n=56) underwent evaluation of myofascial/joint ..
[Analgesics use in patients with chronic musculoskeletal complaints]Robin Holtedahl
Tidsskr Nor Laegeforen 124:1930-2. 2004..Chronic musculoskeletal complaints are common in the clinical setting and a therapeutic challenge. Little is known about the extent and type of pain-relieving drugs used by these patients in Norway...
Treatment of fibromyalgia, myofascial pain, and related disordersJoanne Borg-Stein
Rehabilitation Center, Spaulding Newton Wellesley Rehabilitation Hospital, 65 Walnut Street, Wellesley, MA 02481, USA
Phys Med Rehabil Clin N Am 17:491-510, viii. 2006..of clinical presentations exists, ranging from focal or regional complaints that usually represent myofascial pain syndromes to more wide spread pain that may meet criteria for a diagnosis of fibromyalgia...
Local treatment of tendinopathies and myofascial pain syndromes with the 5-HT3 receptor antagonist tropisetronW Muller
Hochrhein Institute of Rehabilitation Research, Bad Sackingen, Germany
Scand J Rheumatol Suppl 119:44-8. 2004..On the other hand, local injection of prilocaine alone exerted a shorter and weaker effect on the condition...
[Health condition in patients who apply for disability pension]Robin Holtedahl
Oslo, Norway
Tidsskr Nor Laegeforen 126:2654-7. 2006..The main diagnosis is a musculoskeletal disorder in more than one third. The aim of this study was to investigate the health condition of those who apply for disability pension due to musculoskeletal complaints...
Neck pain treatment with acupuncture: does the number of needles matter?Francesco Ceccherelli
Department of Pharmacology and Anesthesiology, University of Padova, Padova, Italy
Clin J Pain 26:807-12. 2010Acupuncture has been successfully used in myofascial pain syndromes. However, the number of needles used, that is, the dose of acupuncture stimulation, to obtain the best antinociceptive efficacy is still a matter of debate...
Central hyperexcitability in chronic musculoskeletal pain: a conceptual breakthrough with multiple clinical implicationsJan Lidbeck
Pain Management Clinic, Hospital of Helsingborg, Helsingborg, Sweden
Pain Res Manag 7:81-92. 2002..Many common chronic musculoskeletal pain syndromes - including regional myofascial pain syndromes, whiplash pain syndromes, refractory work-related neck-shoulder pain, certain types of chronic low back ..
Research Grants
- MECHANISM OF PAIN IN PATIENTS WITH FIBROMYALGIA SYNDROMERoland Staud; Fiscal Year: 2001..abstract_text> ..
- Mechanisms of Acupuncture AnalgesiaRichard Harris; Fiscal Year: 2006..There is a strong institutional commitment to see the applicant succeed in this task due to a tremendous need for well-trained clinical investigators in alternative and complementary medicine. ..
- MECHANISM OF PAIN IN PATIENTS WITH FIBROMYALGIA SYNDROMERoland Staud; Fiscal Year: 2007..In addition, our findings may contribute to the understanding of pain mechanisms related to other chronic pain disorders. ..
- Peripheral and Central Mechanism of Pain in Patients with FibromyalgiaROLAND M STAUD; Fiscal Year: 2010..Either way, we will provide evidence that will characterize the role of local anesthesia, placebo analgesia, or both. Thus patients with FM and other similar pain syndromes may strongly benefit from the results of our study. ..
- Peripheral and Central Mechanism of Pain in Patients with FibromyalgiaRoland Staud; Fiscal Year: 2009..Either way, we will provide evidence that will characterize the role of local anesthesia, placebo analgesia, or both. Thus patients with FM and other similar pain syndromes may strongly benefit from the results of our study. ..
- Peripheral and Central Mechanism of Pain in Patients with FibromyalgiaRoland Staud; Fiscal Year: 2007..Either way, we will provide evidence that will characterize the role of local anesthesia, placebo analgesia, or both. Thus patients with FM and other similar pain syndromes may strongly benefit from the results of our study. ..
- Pathogenesis and Pathophysiological Mechanisms of Myofascial Trigger PointsSiddhartha Sikdar; Fiscal Year: 2010..Our approach would also be broadly applicable to elucidating the underlying mechanisms in other chronic musculoskeletal pain disorders, such low back pain. ..
- Chronic Prostatitis Collaborative Research NetworkRodney Anderson; Fiscal Year: 2007..abstract_text> ..
- Chronic Prostatitis Collaborative Research NetworkRodney Anderson; Fiscal Year: 2007..abstract_text> ..
- Osteopuncture for OA-Associated Knee Pain & DisabilityDebra Weiner; Fiscal Year: 2005..In addition, mechanisms of action will be explored, and the impact of osteopuncture on health care costs determined. ..
- Functional Impact of PENS for 65+ Chronic Low Back PainDebra Weiner; Fiscal Year: 2006....
- Sleep Bruxism and Central Sensitization in Myofascial Face PainKaren Raphael; Fiscal Year: 2007..This understanding is expected to support our long-term goal of improving clinical treatment of MFP by targeting treatment to underlying pain-maintenance mechanisms. ..
- FIBROMYALGIA, DEPRESSION AND MYOFASCIAL TMDKaren Raphael; Fiscal Year: 2002..If only FMS probands have familial M/TMD but M/TMD probands do not, this will support the 2nd hypothesis and indicate that the two disorders are provoked through different pathogenic processes. ..
