arthralgia

Summary

Summary: Pain in the joint.

Top Publications

  1. pmc Patterns and risk factors associated with aromatase inhibitor-related arthralgia among breast cancer survivors
    Jun J Mao
    Department of Family Medicine and Community Health, University of Pennsylvania Health System, Philadelphia, PA, USA
    Cancer 115:3631-9. 2009
  2. pmc Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor
    Angela Chow
    Communicable Disease Centre, Singapore
    J Infect Dis 203:149-57. 2011
  3. doi The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia
    Lotte A van de Stadt
    Department of Immunopathology, Sanquin Research and Landsteiner Laboratorium, Academic Medical Center, Amsterdam, The Netherlands
    Ann Rheum Dis 70:128-33. 2011
  4. doi Chikungunya fever in Singapore: acute clinical and laboratory features, and factors associated with persistent arthralgia
    M K Win
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng 308433, Singapore mar kyaw
    J Clin Virol 49:111-4. 2010
  5. doi Antibody to parvovirus B19 nonstructural protein is associated with chronic arthralgia in patients with chronic fatigue syndrome/myalgic encephalomyelitis
    Jonathan R Kerr
    Department of Cellular and Molecular Medicine, St George s University of London, London, UK
    J Gen Virol 91:893-7. 2010
  6. ncbi Facet joint pain in chronic spinal pain: an evaluation of prevalence and false-positive rate of diagnostic blocks
    Rajeev Manchukonda
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    J Spinal Disord Tech 20:539-45. 2007
  7. ncbi Sonographic and electrodiagnostic evaluations in patients with aromatase inhibitor-related arthralgia
    Omer Dizdar
    Hacettepe University Institute of Oncology, Department of Medical Oncology, Ankara, Turkey
    J Clin Oncol 27:4955-60. 2009
  8. pmc Association between radiographic features of knee osteoarthritis and pain: results from two cohort studies
    Tuhina Neogi
    Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, 650 Albany Street, Boston, MA 02118, USA
    BMJ 339:b2844. 2009
  9. doi Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitor-associated joint symptoms in women with early-stage breast cancer
    Katherine D Crew
    Columbia University, 161 Fort Washington Ave, 10 1068, New York, NY 10032, USA
    J Clin Oncol 28:1154-60. 2010
  10. doi Prospective study to assess short-term intra-articular and tenosynovial changes in the aromatase inhibitor-associated arthralgia syndrome
    Leilani Morales
    Department of Obstetrics and Gynecology, Division of Gynecological Oncology, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    J Clin Oncol 26:3147-52. 2008

Detail Information

Publications247 found, 100 shown here

  1. pmc Patterns and risk factors associated with aromatase inhibitor-related arthralgia among breast cancer survivors
    Jun J Mao
    Department of Family Medicine and Community Health, University of Pennsylvania Health System, Philadelphia, PA, USA
    Cancer 115:3631-9. 2009
    b>Arthralgia is common in postmenopausal breast cancer survivors (BCS) who are receiving aromatase inhibitors (AIs)...
  2. pmc Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor
    Angela Chow
    Communicable Disease Centre, Singapore
    J Infect Dis 203:149-57. 2011
    Chikungunya virus (CHIKV) infection induces arthralgia. The involvement of inflammatory cytokines and chemokines has been suggested, but very little is known about their secretion profile in CHIKV-infected patients.
  3. doi The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia
    Lotte A van de Stadt
    Department of Immunopathology, Sanquin Research and Landsteiner Laboratorium, Academic Medical Center, Amsterdam, The Netherlands
    Ann Rheum Dis 70:128-33. 2011
    To determine the fine specificity of anti-citrullinated protein antibodies (ACPA) in the early phase of arthritis development, the ACPA repertoire in arthralgia patients and the association with arthritis development were studied.
  4. doi Chikungunya fever in Singapore: acute clinical and laboratory features, and factors associated with persistent arthralgia
    M K Win
    Department of Clinical Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng 308433, Singapore mar kyaw
    J Clin Virol 49:111-4. 2010
    ..During the initial outbreak period, a strict containment strategy was adopted and all chikungunya PCR-confirmed cases were isolated and hospitalised at the designated national outbreak management centre...
  5. doi Antibody to parvovirus B19 nonstructural protein is associated with chronic arthralgia in patients with chronic fatigue syndrome/myalgic encephalomyelitis
    Jonathan R Kerr
    Department of Cellular and Molecular Medicine, St George s University of London, London, UK
    J Gen Virol 91:893-7. 2010
    ....
  6. ncbi Facet joint pain in chronic spinal pain: an evaluation of prevalence and false-positive rate of diagnostic blocks
    Rajeev Manchukonda
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    J Spinal Disord Tech 20:539-45. 2007
    ..A retrospective review...
  7. ncbi Sonographic and electrodiagnostic evaluations in patients with aromatase inhibitor-related arthralgia
    Omer Dizdar
    Hacettepe University Institute of Oncology, Department of Medical Oncology, Ankara, Turkey
    J Clin Oncol 27:4955-60. 2009
    To investigate the prevalence of arthralgia in breast cancer patients taking aromatase inhibitors (AIs) and perform a detailed rheumatologic assessment including autoimmune serology, musculoskeletal sonography, and electromyography (EMG) ..
  8. pmc Association between radiographic features of knee osteoarthritis and pain: results from two cohort studies
    Tuhina Neogi
    Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, 650 Albany Street, Boston, MA 02118, USA
    BMJ 339:b2844. 2009
    ..To examine the relation of radiographic features of osteoarthritis to knee pain in people with knees discordant for knee pain in two cohorts...
  9. doi Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitor-associated joint symptoms in women with early-stage breast cancer
    Katherine D Crew
    Columbia University, 161 Fort Washington Ave, 10 1068, New York, NY 10032, USA
    J Clin Oncol 28:1154-60. 2010
    ..Acupuncture is an effective and well-tolerated strategy for managing this common treatment-related side effect...
  10. doi Prospective study to assess short-term intra-articular and tenosynovial changes in the aromatase inhibitor-associated arthralgia syndrome
    Leilani Morales
    Department of Obstetrics and Gynecology, Division of Gynecological Oncology, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    J Clin Oncol 26:3147-52. 2008
    b>Arthralgia is an adverse class effect of aromatase inhibitors (AIs). To date, its exact mechanism remains unclear...
  11. ncbi Mucoid degeneration of the anterior cruciate ligament
    Robrecht Motmans
    Department of Orthopaedic Surgery, Heilig Hart Ziekenhuis Lier, Katholieke Universiteit Leuven, Leuven, Belgium
    Knee Surg Sports Traumatol Arthrosc 17:737-40. 2009
    ..Examination of knee stability after debridement showed a stable ACL. Arthroscopic debridement of the mucoid degeneration of the ACL proved to be a safe and effective method, without causing ligamentary instability in daily activities...
  12. ncbi Pain in older adults: a prevalence study in the Mediterranean region of Catalonia
    Jordi Miró
    Department of Psychology, Rovira i Virgili University, Carretera de Valls, S N, 43007 Tarragona, Spain
    Eur J Pain 11:83-92. 2007
    ..This study provides new evidence that pain is an important problem for the older adult, one that severely impacts on their health status, causing disability and reduced ability to function, particularly in older women...
  13. ncbi Mucoid degeneration of the anterior cruciate ligament
    S Fealy
    Department of Sports Medicine, Hospital for Special Surgery, affiliated with Cornell University Medical Center, New York, New York, USA
    Arthroscopy 17:E37. 2001
    ..We present this case to demonstrate the presence of intraligamentous mucoid degeneration in the ACL as a source of knee pain without instability. Partial ACL debridement did not preclude adequate knee stability...
  14. ncbi Quantifying the impact of transient joint symptoms, chronic joint symptoms, and arthritis: a population-based approach
    Lucy Busija
    The University of Melbourne, Melbourne, Victoria, Australia
    Arthritis Rheum 61:1312-21. 2009
    ....
  15. ncbi Pain and OA
    J J McDougall
    Department of Physiology and Biophysics, University of Calgary, Calgary, AB, Canada
    J Musculoskelet Neuronal Interact 6:385-6. 2006
  16. ncbi Mucoid degeneration of the anterior cruciate ligament
    Chin Jung Hsu
    Department of Orthopedics, China Medical University Hospital, Taichung, Taiwan, ROC
    J Chin Med Assoc 69:449-52. 2006
    ..Arthroscopic debridement of the mucoid degeneration of the ACL was safe and effective in these 2 patients...
  17. pmc A treatment applying a biomechanical device to the feet of patients with knee osteoarthritis results in reduced pain and improved function: a prospective controlled study
    Yaron Bar-Ziv
    Department of Orthopedic Surgery, Assaf Harofeh Medical Center, Zerifin, Israel
    BMC Musculoskelet Disord 11:179. 2010
    ..This study examined the effect of treatment with a novel biomechanical device on the level of pain and function in patients with knee OA...
  18. ncbi Mucoid degeneration of the anterior cruciate ligament--a report of two cases
    Makoto Nishimori
    Department of Orthopedic Surgery, JA Onomichi General Hospital, Onomichi, Hiroshima 722 8508, Japan
    Magn Reson Imaging 22:1325-8. 2004
    ..If this disease is considered preoperatively, it can be diagnosed easily based on characteristic findings...
  19. doi Field evaluation of clinical features during chikungunya outbreak in Mayotte, 2005-2006
    Daouda Sissoko
    Institut de Veille Sanitaire, Cellule interrégionale d Epidémiologie de la Réunion Mayotte, 2 bis Av G Brassens, Saint Denis Messag 9, France
    Trop Med Int Health 15:600-7. 2010
    ..To record and assess the clinical features of chikungunya fever (CHIKF), with a view to enable diagnosis based on clinical criteria rather than costly laboratory procedures in field conditions...
  20. ncbi Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune response
    Jean Jacques Hoarau
    Biology Unit, Centre Hospitalier Régional Nord Félix Guyon and Cyclotron Réunion Océan Indien, Universite de la Reunion, St Denis, France
    J Immunol 184:5914-27. 2010
    ..virus (CHIKV), produce a transient illness in humans, but severe forms leading to chronic incapacitating arthralgia/arthritis have been reported by mechanisms largely ill-characterized...
  21. pmc The visual analogue WOMAC 3.0 scale--internal validity and responsiveness of the VAS version
    Paula Kersten
    School of Health Sciences, University of Southampton, Highfield, Southampton, UK
    BMC Musculoskelet Disord 11:80. 2010
    ..However, there is relatively little evidence to support the use of the Visual Analogue Scale (VAS) version of the scale. We aimed to explore the internal validity and responsiveness of this VAS version of the WOMAC...
  22. doi Isolated resurfacing of the previously unresurfaced patella total knee arthroplasty
    Ryan M Garcia
    Department of Orthopaedic Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Arthroplasty 25:754-8. 2010
    ..Isolated patellar resurfacing for anterior knee pain in total knee arthroplasty with an unresurfaced patella has a low morbidity and revision rate but may not provide patients with predictable symptomatic improvement...
  23. pmc Management of chronic knee pain: a survey of patient preferences and treatment received
    Helene L Mitchell
    Rehabilitation Research Unit King s College London, Dulwich Community Hospital, London, UK
    BMC Musculoskelet Disord 9:123. 2008
    ..In this study the management received by people with chronic knee pain, their management preferences and reasons for these preferences were recorded...
  24. ncbi Effects of training on general practitioners' management of pain in osteoarthritis: a randomized multicenter study
    Olivier Chassany
    Département de la Recherche Clinique et du Développement de l Assistance Publique, Hopitaux de Paris, France
    J Rheumatol 33:1827-34. 2006
    ..To evaluate the effects of a short interactive training program for general practitioners (GP) on pain management in patients with osteoarthritis (OA)...
  25. pmc A prospective study of aromatase inhibitor-associated musculoskeletal symptoms and abnormalities on serial high-resolution wrist ultrasonography
    N Lynn Henry
    Breast Oncology Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48109 5419, USA
    Cancer 116:4360-7. 2010
    ..Tendon sheath fluid and tenosynovial changes have been demonstrated by imaging symptomatic patients who were treated with AIs. The authors hypothesized that these abnormalities are correlated with AIMSS...
  26. ncbi Long-term benefits and repeated treatment cycles of intra-articular sodium hyaluronate (Hyalgan) in patients with osteoarthritis of the knee
    Gernot Kolarz
    Institut für Rheumatologie der Kurstadt Baden, Baden, Austria
    Semin Arthritis Rheum 32:310-9. 2003
    ..The benefits of a second treatment cycle in patients with renewed need for therapy also were examined...
  27. doi Joint pain
    Hans Georg Schaible
    Institute of Physiology 1 Neurophysiology, University Hospital Jena, Teichgraben 8, 07740 Jena, Germany
    Exp Brain Res 196:153-62. 2009
    ..The overview will also address long-term changes of pain-related behavior, response properties of neurons and receptor expression in chronic animal models of arthritis...
  28. ncbi Joint pain with aromatase inhibitors: abnormal frequency of Sjögren's syndrome
    Michel Laroche
    Service de Rhumatologie, CHU Rangueil, 1 avenue Jean Poulhes, Toulouse, France
    J Rheumatol 34:2259-63. 2007
    ..With these treatments, joint pain is frequent (30% to 40%) and quite often disabling (5% to 10%). Our objective was to investigate the origin of the pain induced by the anti-aromatases...
  29. doi Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain
    Kay E McNamee
    Kennedy Institute of Rheumatology, Imperial College London, London W6 8LH, UK
    Pain 149:386-92. 2010
    ..They also suggest that, unlike post-operative pain, induction of pain in OA may not necessarily be driven by classical inflammatory processes...
  30. ncbi Risk factors for joint symptoms in patients enrolled in the ATAC trial: a retrospective, exploratory analysis
    Ivana Sestak
    Cancer Research UK, Centre for Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, London, UK
    Lancet Oncol 9:866-72. 2008
    Joint symptoms (eg, arthralgia and arthritis) are a well-known side-effect of aromatase inhibitors. Low oestrogen concentrations and postmenopausal status are associated with the development of these symptoms...
  31. doi Menopausal arthralgia: Fact or fiction
    Malgorzata Magliano
    Stoke Mandeville Hospital, Aylesbury, HP21 8AL, UK
    Maturitas 67:29-33. 2010
    b>Arthralgia is experienced by more then half of the women around the time of menopause...
  32. doi Aromatase inhibitor-induced arthralgia in early breast cancer: what do we know and how can we find out more?
    Omar S Din
    Academic Unit of Clinical Oncology, Cancer Research Centre, Weston Park Hospital, Sheffield, S10 2SJ, UK
    Breast Cancer Res Treat 120:525-38. 2010
    ..b>Arthralgia was a somewhat unexpected side effect of this class of agents and has proven to be potentially problematic in ..
  33. ncbi Osteoarthritis and joint pain
    Bruce L Kidd
    Bone and Joint Research Unit, Queen Mary School of Medicine, Charterhouse Square, London E1 2AD, UK
    Pain 123:6-9. 2006
  34. ncbi Population requirement for primary hip-replacement surgery: a cross-sectional study
    S Frankel
    Department of Social Medicine, University of Bristol
    Lancet 353:1304-9. 1999
    ..We set out to estimate the population requirement for primary total hip replacement in England...
  35. ncbi Aromatase inhibitors and the syndrome of arthralgias with estrogen deprivation
    David T Felson
    Boston University Clinical Epidemiology Research and Training Unit, Boston, Massachusetts, USA
    Arthritis Rheum 52:2594-8. 2005
  36. doi Factors associated with persistence of arthralgia among Chikungunya virus-infected travellers: report of 42 French cases
    Sophie Larrieu
    Cellule Interrégionale d Epidémiologie d Aquitaine, Bordeaux, France
    J Clin Virol 47:85-8. 2010
    ..In 2005-2006, a major epidemic of CHIKV infection occurred in the Islands of the south-western Indian Ocean, and longstanding manifestations seemed to be more frequent than described before...
  37. ncbi Long term effects of intra-articular botulinum toxin A for refractory joint pain
    M L Mahowald
    Minneapolis VAMC, University of Minnesota Department of Medicine, USA
    Neurotox Res 9:179-88. 2006
    ....
  38. pmc 25-hydroxyvitamin D concentration, vitamin D intake and joint symptoms in postmenopausal women
    Rowan T Chlebowski
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, United States
    Maturitas 68:73-8. 2011
    ..However, the results are mixed and few studies have evaluated associations between 25(OH) D concentrations and both total vitamin D intake and clinical joint symptoms...
  39. pmc Arthritis and pain. Future targets to control osteoarthritis pain
    Andy Dray
    AstraZeneca R and D Montreal, Frederick Banting St, Montreal H4S 1Z9, Canada
    Arthritis Res Ther 9:212. 2007
    ..Future neurological treatments of pain appear optimistic but will require the systematic evaluation of emerging opportunities...
  40. pmc Perceptions of joint pain and feeling well in older people who reported being healthy: a qualitative study
    Janet Grime
    Keele University, Arthritis Research UK Primary Care Centre, Keele
    Br J Gen Pract 60:597-603. 2010
    ..Professionals have mixed views about this. One concern is that seeing osteoarthritis as a result of 'wear and tear' leads to restricting exercise in order to avoid further wear...
  41. doi Natural course of knee osteoarthritis in middle-aged subjects with knee pain: 12-year follow-up using clinical and radiographic criteria
    C A Thorstensson
    Research and Development Centre, Spenshult, S 313 92 Oskarström, Sweden
    Ann Rheum Dis 68:1890-3. 2009
    ..To explore the natural course of knee osteoarthritis (OA) in a middle-aged population with chronic knee pain...
  42. doi Persistent arthralgia associated with chikungunya virus: a study of 88 adult patients on reunion island
    Gianandrea Borgherini
    Service de Pneumologie et Maladies Infectieuses, Groupe Hospitalier Sud Reunion, Saint Pierre, La Reunion, France
    Clin Infect Dis 47:469-75. 2008
    An outbreak of chikungunya virus infection occurred on Reunion Island during the period 2005-2006. Persistent arthralgia after chikungunya virus infection has been reported, but few studies have treated this aspect of the disease.
  43. pmc Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial
    Christos Markopoulos
    Hellenic Society of Breast Surgeons, 6 Eslin Street, Athens, Greece
    Breast Cancer Res 12:R24. 2010
    ....
  44. ncbi Effects of duodenal seal oil administration in patients with inflammatory bowel disease
    Gulen Arslan
    Division of Gastroenterology, Institute of Medicine, Haukeland University Hospital, N 5021 Bergen, Norway
    Lipids 37:935-40. 2002
    ..The results suggest positive effects of seal oil in patients with IBD, especially on IBD-associated joint pain. Further controlled studies are warranted...
  45. doi Inferior or double joint spaces injection versus superior joint space injection for temporomandibular disorders: a systematic review and meta-analysis
    Chunjie Li
    Department of Oral and Maxillofacial Surgery, State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, Chengdu, China
    J Oral Maxillofac Surg 70:37-44. 2012
    ..To compare the effect and safety of inferior or double temporomandibular joint spaces drug injection versus superior temporomandibular joint space injection in the treatment of temporomandibular disorders...
  46. pmc Does ultrasound correlate with surgical or histologic findings in greater trochanteric pain syndrome? A pilot study
    A M Fearon
    Australian National University, Canberra, Australia
    Clin Orthop Relat Res 468:1838-44. 2010
    ..Greater trochanteric pain syndrome can be severely debilitating. Ideal imaging modalities are not established, treatments are not reliably evaluated, and the underlying pathology is not well understood...
  47. ncbi Magnetic resonance imaging and musculoskeletal ultrasonography detect and characterize covert inflammatory arthropathy in systemic sclerosis patients with arthralgia
    Sarang Chitale
    Department of Rheumatology, Inflammation Research Unit, School of Clinical Sciences, University of Liverpool, Liverpool L9 7AL, UK
    Rheumatology (Oxford) 49:2357-61. 2010
    ..We explored the role of MRI and musculoskeletal ultrasonography (MSUS) in detecting and characterizing synovial inflammation in SSc patients with arthralgia while comparing the two imaging modalities.
  48. pmc Leg-length inequality is not associated with greater trochanteric pain syndrome
    Neil A Segal
    Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 0728 JPP, Iowa City, IA 52242 1088, USA
    Arthritis Res Ther 10:R62. 2008
    ..Although leg-length inequality has been suggested as a potential risk factor for GTPS, this widely held assumption has not been tested...
  49. ncbi Pressure-pain thresholds and MRI effusions in TMJ arthralgia
    J R Shaefer
    Department of Diagnostic and Surgical Sciences, University of Minnesota, School of Dentistry, Minneapolis, USA
    J Dent Res 80:1935-9. 2001
    It has been suggested that MRI-depicted effusions identify patients with TMJ arthralgia. The Research Diagnostic Criteria (RDC) propose a pressure-pain threshold (PPT) of 1 pound for the identification of TMJ arthralgia...
  50. doi Long-term chikungunya infection clinical manifestations after an outbreak in Italy: a prognostic cohort study
    M L Moro
    Area Rischio Infettivo, Agenzia Sanitaria e Sociale Regione Emilia Romagna, Viale Aldo Moro 21, Bologna, Italy
    J Infect 65:165-72. 2012
    ..Following a Chikungunya (CHIKV) outbreak in Italy, a cohort study was conducted to describe the infection long-term clinical course and outcome...
  51. ncbi An open-label trial of the selective cyclo-oxygenase-2 inhibitor, rofecoxib, in inflammatory bowel disease-associated peripheral arthritis and arthralgia
    W Reinisch
    Department of Internal Medicine IV, Division of Gastroenterology and Hepatology, University of Vienna, Vienna, Austria
    Aliment Pharmacol Ther 17:1371-80. 2003
    ..Conventional non-steroidal anti-inflammatory drugs have been associated with an increased risk of exacerbation of inflammatory bowel disease...
  52. pmc Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia
    Laurence Dupuis-Maguiraga
    CEA, Division of Immuno Virologie, Institute of Emerging Diseases and Innovative Therapies, Fontenay aux Roses, France
    PLoS Negl Trop Dis 6:e1446. 2012
    ..In humans, it causes a disease characterized by a typical acute infection, sometimes followed by persistent arthralgia and myalgia lasting months or years...
  53. ncbi Probiotics in arthralgia and spondyloarthropathies in patients with inflammatory bowel disease. Prospective randomized trials are necessary
    O Karimi
    Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands
    Rev Esp Enferm Dig 97:570-4. 2005
    ..In this review we will focus on the pathogenesis of spondyloarthropathies and arthralgia in patients suffering from inflammatory bowel disease...
  54. doi Hand problems in community-dwelling older adults: onset and effect on global physical function over a 3-year period
    E Thomas
    Arthritis Research Campaign National Primary Care Centre, Primary Care Sciences, Keele University, Keele, Staffordshire ST55BG, UK
    Rheumatology (Oxford) 48:183-7. 2009
    ..To determine the impact of the onset of hand problems on global physical functioning in community-dwelling older adults...
  55. ncbi Ganglion cyst of the anterior cruciate ligament: a case report
    B Dinakar
    Fujairah Hospital, Fujairah, UAE
    J Orthop Surg (Hong Kong) 13:181-5. 2005
    ..Ganglia are typically treated by arthroscopic excision and debridement. We report a case of ganglion cyst of the anterior cruciate ligament in a 16-year-old man...
  56. ncbi Antinociceptive effects of tumor necrosis factor alpha neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal target
    Michael K Boettger
    University Hospital of Jena, Jena, Germany
    Arthritis Rheum 58:2368-78. 2008
    ....
  57. doi Gait differs between unilateral and bilateral knee osteoarthritis
    Mark W Creaby
    Centre of Physical Activity Across the Lifespan, School of Exercise Science, Australian Catholic University, Brisbane, Queensland, Australia
    Arch Phys Med Rehabil 93:822-7. 2012
    ....
  58. ncbi Chronic fatigue syndrome and arthralgia following parvovirus B19 infection
    Jonathan R Kerr
    Department of Microbiology, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College School of Medicine, London, UK
    J Rheumatol 29:595-602. 2002
    To determine the incidence of arthralgia and fatigue complicating B19 infection, along with associated B19 markers and autoantibodies.
  59. ncbi Intra-articular morphine as analgesic in temporomandibular joint arthralgia/osteoarthritis
    T List
    TMD Unit, Specialist Centre for Oral Rehabilitation, SE 581 85 Linkoping, Sweden
    Pain 94:275-82. 2001
    ..a.) of morphine in 53 patients with unilateral arthralgia/osteoarthritis of the temporomandibular joint (TMJ)...
  60. doi Surgical repair of the gluteal tendons: a report of 72 cases
    Michael J Walsh
    Hawkesbury District Health Service, Windsor, NSW, Australia
    J Arthroplasty 26:1514-9. 2011
    ..00001). Surgical reconstruction of detached gluteal tendons causing chronic lateral hip pain addresses the problem directly and reliably relieves the symptoms of so-called "trochanteric bursitis."..
  61. ncbi Reliability of the lateral pull test and tilt test to assess patellar alignment in subjects with symptomatic knees: student raters
    C J Watson
    University of Texas Southwestern Medical Center, Dallas 75390 8876, USA
    J Orthop Sports Phys Ther 31:368-74. 2001
    ..Test-retest reliability with blinded testers...
  62. doi Panniculitis with arthralgia in patients with melanoma treated with selective BRAF inhibitors and its management
    Lisa Zimmer
    Department of Dermatology, University Hospital Essen, Essen, Germany
    Arch Dermatol 148:357-61. 2012
    ..Painful lobular panniculitis appears to be a novel cutaneous adverse effect of selective BRAF inhibitors...
  63. ncbi Prevalence of self-reported peripheral joint pain and swelling in an Italian population: the Chiavari study
    M A Cimmino
    Unita di Reumatologia, Dipartimento di Medicina Interna, Universita di Genova, Italy
    Clin Exp Rheumatol 19:35-40. 2001
    ..To evaluate the prevalence of self-reported joint pain and swelling in the peripheral joints of subjects from an Italian general population. To correlate the result with demographic data and physical activity...
  64. doi Meniscal root injury and spontaneous osteonecrosis of the knee: an observation
    D D Robertson
    University of Pittsburgh, Pittsburgh, PA, USA
    J Bone Joint Surg Br 91:190-5. 2009
    ..Although tears of the posterior root of the medial meniscus were frequently present in patients with spontaneous osteonecrosis of the knee, this does not prove cause and effect. Further study is warranted...
  65. ncbi [Reduction of arthrosis associated knee pain through a single intra-articular injection of synthetic hyaluronic acid]
    D Krocker
    Centrum für Muskuloskeletale Chirurgie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Z Rheumatol 65:327-31. 2006
    ..Clinical outcome using Durolane should be compared with the results of studies using hyaluronic acids or glucocorticoids...
  66. doi Getting a grip on aromatase inhibitor-associated arthralgias
    Dawn L Hershman
    J Clin Oncol 26:3120-1. 2008
  67. ncbi Associations between physical examination and self-reported physical function in older community-dwelling adults with knee pain
    Laurence Wood
    Primary Care Musculoskeletal Research Centre, Keele University, Keele, Stoke on Trent ST5 5BG, United Kingdom
    Phys Ther 88:33-42. 2008
    ..Clinicians depend on the history and physical examination to direct treatment. The purpose of this study was to examine the associations between simple physical examination tests and self-reported physical functional limitations...
  68. ncbi Improvement of arthritis and arthralgia after treatment with infliximab (Remicade) in a German prospective, open-label, multicenter trial in refractory Crohn's disease
    Hans Herfarth
    Am J Gastroenterol 97:2688-90. 2002
  69. ncbi The role of the shared epitope in arthralgia with anti-cyclic citrullinated peptide antibodies (anti-CCP), and its effect on anti-CCP levels
    W H Bos
    Jan van Breemen Institute, Department of Rheumatology, Amsterdam, The Netherlands
    Ann Rheum Dis 67:1347-50. 2008
    Patients presenting with both arthralgia and antibodies to cyclic citrullinated peptide (anti-CCP) have an increased risk of developing rheumatoid arthritis (RA)...
  70. ncbi Two cases with pachydermoperiostosis and discussion of tamoxifen citrate treatment for arthralgia
    Aysenur Okten
    Department of Pediatrics, School of Medicine, Karadeniz Technical University, Pediatri Anabilim Dali, 61080 Trabzon, Turkey
    Clin Rheumatol 26:8-11. 2007
    ..It is a self-limiting condition but arthralgia may be as severe as limiting social life and activity, and it is the main complaint to be treated...
  71. ncbi [The effect of L-Glutamine and Shakuyaku-Kanzo-to for paclitaxel-induced myalgia/arthralgia]
    Kosei Hasegawa
    Dept of Obstetrics and Gynecology, Okayama University Medical School
    Gan To Kagaku Ryoho 29:569-74. 2002
    Myalgia/arthralgia is a crucial side effect of paclitaxel, and may become the major dose-limiting side effect. However, this is a situation where there is little effective preventive treatment...
  72. pmc The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature
    John Bedson
    Arthritis Research Campaign National Primary Care Centre, Keele University, Staffordshire, ST5 5BG, United Kingdom
    BMC Musculoskelet Disord 9:116. 2008
    ....
  73. ncbi Sindbis viruses and other alphaviruses as cause of human arthritic disease
    M Laine
    Keuruu Health Center, Keuruu, Finland
    J Intern Med 256:457-71. 2004
    ..Several factors related to the viruses, their hosts, and global environmental changes may affect the spread of these viruses. All over the world arbovirus-caused diseases have increased, because of global changes...
  74. doi Vitamin D threshold to prevent aromatase inhibitor-induced arthralgia: a prospective cohort study
    Daniel Prieto-Alhambra
    Department of Internal Medicine, URFOA IMIM Hospital del Mar, Parc de Salut Mar, Autonomous University of Barcelona, Barcelona, Spain
    Breast Cancer Res Treat 125:869-78. 2011
    Aromatase inhibitor (AI)-associated arthralgia limits adherence to therapy in breast cancer. The pathophysiology may involve vitamin D status...
  75. ncbi Multiple joint pain and lower extremity disability in middle and old age
    George Peat
    Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, UK
    Disabil Rehabil 28:1543-9. 2006
    ..To determine whether the extent of multiple-site lower extremity joint pain contributes to disability in middle and old age and describe patterns of severity in site-specific measures amongst those with multiple-site pain...
  76. doi Aromatase inhibitor therapy: toxicities and management strategies in the treatment of postmenopausal women with hormone-sensitive early breast cancer
    Susan F Dent
    The Ottawa Hospital Cancer Centre, The University of Ottawa, 501 Smyth Rd, Ottawa, ON, K1H 8L6, Canada
    Breast Cancer Res Treat 126:295-310. 2011
    ..Aromatase inhibitors are generally well tolerated; however, certain side effects, particularly arthralgia/musculoskeletal symptoms and gynecologic effects, may result in poor adherence to treatment...
  77. ncbi The association of bone marrow lesions with pain in knee osteoarthritis
    D T Felson
    Boston University School of Medicine, 715 Albany Street, A203, Boston, MA 02118, USA
    Ann Intern Med 134:541-9. 2001
    ..Among persons with knee pain, bone marrow lesions were not associated with pain severity. CONCLUSIONS: Bone marrow lesions on MRI are strongly associated with the presence of pain in knee osteoarthritis...
  78. ncbi Animal models of osteoarthritis
    Kenneth D Brandt
    Rheumatology Division, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Biorheology 39:221-35. 2002
    ..Indeed, it should not be assumed a priori that reduction in the rate of progression of joint damage in OA will be associated with a reduction in joint pain...
  79. ncbi Minimal clinically important changes in chronic musculoskeletal pain intensity measured on a numerical rating scale
    Fausto Salaffi
    Department of Rheumatology, University of Ancona, Ospedale A Murri, ASL5, Via dei Colli 52, 60035 Jesi Ancona, Italy
    Eur J Pain 8:283-91. 2004
    ....
  80. pmc Help-seeking behaviour among people living with chronic hip or knee pain in the community
    Carina A Thorstensson
    Research and Development Centre, Spenshult Hospital for Rheumatic Diseases, Oskarström, Sweden
    BMC Musculoskelet Disord 10:153. 2009
    ..This study explores the importance of several potential risk factors on help seeking across different practitioner groups, among adults living with chronic hip or knee pain in a large community sample...
  81. pmc Feasibility trial of electroacupuncture for aromatase inhibitor--related arthralgia in breast cancer survivors
    James J Mao
    Department of Family Medicine and Community Health, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Integr Cancer Ther 8:123-9. 2009
    b>Arthralgia affects postmenopausal women receiving aromatase inhibitors (AIs) for breast cancer...
  82. pmc Corticosteroid injections for greater trochanteric pain syndrome: a randomized controlled trial in primary care
    Aaltien Brinks
    Department of General Practice, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Fam Med 9:226-34. 2011
    ..We undertook a study to evaluate the effectiveness of corticosteroid injections in primary care patients with greater trochanteric pain syndrome (GTPS)...
  83. pmc Short and medium-term effects of an education self-management program for individuals with osteoarthritis of the knee, designed and delivered by health professionals: a quality assurance study
    Sophie Coleman
    Arthritis Foundation of Western Australia, PO Box 34, Wembley, Western Australia, 6913, Australia
    BMC Musculoskelet Disord 9:117. 2008
    ....
  84. ncbi Modulation of the gait deficit in arthritic rats by infusions of muscimol and bicuculline
    Shabana U Simjee
    School of Biological Sciences, The University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Pain 109:453-60. 2004
    ..The results suggest that the development of arthritic pain is increased in the absence of GABA(A) receptor tone and that increasing GABA(A) receptor tone can reduce arthritic pain but does not affect the disease process...
  85. ncbi Using the CatWalk method to assess weight-bearing and pain behaviour in walking rats with ankle joint monoarthritis induced by carrageenan: effects of morphine and rofecoxib
    Kristina Angeby-Möller
    AstraZeneca R and D Sodertalje, Local Discovery Research Area CNS and Pain Control, Sodertalje, Sweden
    J Neurosci Methods 174:1-9. 2008
    ..In conclusion, behavioural effects interpreted as reflecting movement-related pain in monoarthritic rats and pharmacological treatment of the monoarthritis can objectively and efficiently be quantified in detail by the CatWalk method...
  86. doi Effect of vitamin D supplementation on serum 25-hydroxy vitamin D levels, joint pain, and fatigue in women starting adjuvant letrozole treatment for breast cancer
    Qamar J Khan
    Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA
    Breast Cancer Res Treat 119:111-8. 2010
    ..Vitamin D3 supplementation with 50,000 IU per week is safe, significantly increases 25OHD levels, and may reduce disability from AI-induced arthralgias...
  87. ncbi Knee buckling: prevalence, risk factors, and associated limitations in function
    David T Felson
    Boston University School of Medicine, Hebrew SeniorLife, Brigham and Women s Hospital, and Boston Medical Center, Boston, Massachusetts 02118, USA
    Ann Intern Med 147:534-40. 2007
    ..Knee buckling is common in persons with advanced knee osteoarthritis and after orthopedic procedures. Its prevalence in the community is unknown...
  88. ncbi Hamato-lunate impingement: an uncommon cause of ulnar-sided wrist pain
    A J Thurston
    Department of Surgery, Wellington School of Medicine, Wellington, New Zealand
    Arthroscopy 16:540-4. 2000
    ..The pain could be reproduced by a modification of the Lichtman test. The diagnosis was confirmed by arthroscopy. All 4 patients responded favorably to resection of the head of the hamate...
  89. ncbi Magnetic resonance imaging evaluation of patellofemoral malalignment
    Jocelyn R Wittstein
    Division of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA
    Arthroscopy 22:643-9. 2006
    ....
  90. ncbi Comparison of symptoms and clinical findings in subgroups of individuals with patellofemoral pain
    Jan Naslund
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Physiother Theory Pract 22:105-18. 2006
    ..The main finding in our study on patients clinically diagnosed with PFPS is that possible pathologies cannot be detected from the patient's history or from commonly used clinical tests...
  91. ncbi Which factors predict the long-term outcome in chronic patellofemoral pain syndrome? A 7-yr prospective follow-up study
    A Natri
    Tampere Research Center of Sports Medicine and Accident and Trauma Research Center, UKK Institute, Finland
    Med Sci Sports Exerc 30:1572-7. 1998
    ..The aim of this prospective study was to determine which factors predict the long-term (7-yr) outcome of conservative treatment of chronic patellofemoral pain syndrome...
  92. ncbi Imaging of ulnar-sided wrist pain
    Claire A Coggins
    Department of Radiology, Virginia Commonwealth University, Main Hospital, 3rd Floor, Room 3 343, 1250 East Marshall Street, Richmond, VA 23298, USA
    Clin Sports Med 25:505-26, vii. 2006
    ..Conventional radiographs, conventional arthrography, CT, MRI, and MR arthrography are useful modalities that are often used in concert to help guide diagnosis and treatment...
  93. ncbi Chikungunya fever in travelers: clinical presentation and course
    Winfried Taubitz
    Department of Infectious Diseases and Tropical Medicine, University Munich, Germany
    Clin Infect Dis 45:e1-4. 2007
    ..5 million patients, including travelers who have visited these areas...
  94. ncbi Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging
    David T Felson
    Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Arthritis Rheum 56:2986-92. 2007
    ..This study was undertaken to determine whether enlarging BMLs are associated with new knee pain...
  95. doi Predictors of onset and progression of knee pain in adults living in the community. A prospective study
    C Jinks
    Primary Care Musculoskeletal Research Centre, Primary Care Sciences, Keele University, Keele, Staffordshire ST5 5BG, UK
    Rheumatology (Oxford) 47:368-74. 2008
    ..To investigate determinants of the onset and progression of knee pain in a population-based sample of people aged > or = 50 yrs...
  96. ncbi Aromatase inhibitor-induced arthralgia: clinical experience and treatment recommendations
    R E Coleman
    Academic Unit of Clinical Oncology, Weston Park Hospital, Witham Road, Sheffield S10 2SJ, UK
    Cancer Treat Rev 34:275-82. 2008
    ..However, compared with tamoxifen, an elevated incidence of arthralgia has been observed during AI treatment...
  97. ncbi Effect of meniscal damage on the development of frequent knee pain, aching, or stiffness
    M Englund
    Clinical Epidemiology Branch and Training Unit, Boston University School of Medicine, 650 Albany Street, Boston, MA 02118, USA
    Arthritis Rheum 56:4048-54. 2007
    ..To evaluate the effect of meniscal damage on the development of frequent knee pain, aching, or stiffness in middle-aged and older adults...
  98. ncbi Determinants of reduced walking speed in people with musculoskeletal pain
    Salma Ayis
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Rheumatol 34:1905-12. 2007
    ..People with musculoskeletal disease often have reduced walking speed. We investigated determinants of slower walking, other than musculoskeletal disease, that might provide valuable additional targets for therapy...
  99. ncbi Brief report: use of complementary and alternative medicine and psychological functioning in Latino children with juvenile idiopathic arthritis or arthralgia
    Kathy Zebracki
    Loyola University Chicago, Department of Psychology, IL 60626, USA
    J Pediatr Psychol 32:1006-10. 2007
    To describe the use of complementary and alternative medicine (CAM) and its relationship to symptoms of anxiety, depression, and dysthymia in Latino children with juvenile idiopathic arthritis (JIA) or arthralgia.
  100. pmc Knee complaints seen in general practice: active sport participants versus non-sport participants
    Marienke van Middelkoop
    Department of General Practice, Erasmus MC, Rotterdam, The Netherlands
    BMC Musculoskelet Disord 9:36. 2008
    ..Further, differences in the initial policy of the GP, medical consumption, and outcome at one-year follow-up were also investigated...
  101. ncbi Aromatase inhibitor-associated arthralgia and/ or bone pain: frequency and characterization in non-clinical trial patients
    Cary A Presant
    Wilshire Oncology Medical Group, West Covina, CA 91790, USA
    Clin Breast Cancer 7:775-8. 2007
    The frequency of aromatase inhibitor (AI)-associated arthralgia and/or bone pain in clinical practice is not known.

Research Grants105 found, 100 shown here

  1. TOGAVIRUS TROPISM FOR BONES, JOINTS, AND CNS
    Mark Heise; Fiscal Year: 2004
    Togavirus infection of humans is characterized by acute and persistent arthritis/arthralgia, as well as viral encephalitis. Infection of adult mice with S.A...
  2. RCT of exercise on aromatase inhibitor side effects in breast cancer survivors
    Melinda L Irwin; Fiscal Year: 2010
    ..Data from the large adjuvant trials evaluating the use of the AI's indicate that arthralgia is one of the major toxicities associated with AI therapy and one of the most common reasons for AI treatment ..
  3. Determining Molecular Mechanisms of Chikungunya Virulence and Attenuation
    KATHERINE RYMAN; Fiscal Year: 2009
    ..The symptoms of arthralgia/arthritis frequently persist for weeks or months later the initial illness has disappeared...
  4. Determining Molecular Mechanisms of Chikungunya Virulence and Attenuation
    KATHERINE D RYMAN; Fiscal Year: 2009
    ..The symptoms of arthralgia/arthritis frequently persist for weeks or months later the initial illness has disappeared...
  5. Determining Molecular Mechanisms of Chikungunya Virulence and Attenuation
    KATHERINE D RYMAN; Fiscal Year: 2010
    ..The symptoms of arthralgia/arthritis frequently persist for weeks or months later the initial illness has disappeared...
  6. RCT of exercise on aromatase inhibitor side effects in breast cancer survivors
    Melinda Irwin; Fiscal Year: 2009
    ..Data from the large adjuvant trials evaluating the use of the AI's indicate that arthralgia is one of the major toxicities associated with AI therapy and one of the most common reasons for AI treatment ..
  7. Acupuncture for Aromatase Inhibitor-Related Arthralgias in Breast Cancer Patients
    Dawn Hershman; Fiscal Year: 2012
    ..However, up to 50% of women on AI report symptoms of debilitating musculoskeletal pain and joint arthralgia that can lead to noncompliance and early discontinuation, thereby impacting survival...
  8. Oral BMS-275291 Metalloproteinase Inhibitor in Cancer
    Naiyer Rizvi; Fiscal Year: 2000
    ..release from the cell surface, and sheddase inhibition is hypothesized to play a role in the dose limiting arthralgia/myalgia reported for some hydroxamate-based MMPIs...
  9. Pain in adolescents: biologic/psychosocial risk factors
    Linda LeResche; Fiscal Year: 2000
    ..and b) estimate the prevalence of specific clinical subtypes of TMD (myofascial pain, disc displacements, arthralgia, arthritis/arthrosis) using standardized examination methods and diagnostic algorithms...
  10. Pain in adolescents: biologic/psychosocial risk factors
    Linda LeResche; Fiscal Year: 2001
    ..and b) estimate the prevalence of specific clinical subtypes of TMD (myofascial pain, disc displacements, arthralgia, arthritis/arthrosis) using standardized examination methods and diagnostic algorithms...
  11. Pain in adolescents: biologic/psychosocial risk factors
    Linda LeResche; Fiscal Year: 1999
    ..and b) estimate the prevalence of specific clinical subtypes of TMD (myofascial pain, disc displacements, arthralgia, arthritis/arthrosis) using standardized examination methods and diagnostic algorithms...
  12. SURROGATE ASSAY FOR B19 PARVOVIRUS SERUM NEUTRALIZATION
    GEETHA BANSAL; Fiscal Year: 1990
    ..disease syndromes including mild illness with rash in children (erythema infectiosum), febrile illness with arthralgia or arthritis in adults, serious transient or chronic aplastic anemia in hematology, oncology, and ..
  13. Mechanisms of Chikungunya Virus Binding and Entry
    LAURIE SILVA; Fiscal Year: 2012
    ..human pathogen causes an acute febrile illness characterized by a maculopapular rash and incapacitating arthralgia, which can evolve to chronic arthritis...
  14. TOGAVIRUS TROPISM FOR BONES, JOINTS, AND CNS
    Mark Heise; Fiscal Year: 2000
    Togavirus infection of humans is characterized by acute and persistent arthritis/arthralgia, as well as viral encephalitis. Infection of adult mice with S.A...
  15. TOGAVIRUS TROPISM FOR BONES, JOINTS, AND CNS
    Mark Heise; Fiscal Year: 2003
    Togavirus infection of humans is characterized by acute and persistent arthritis/arthralgia, as well as viral encephalitis. Infection of adult mice with S.A...
  16. TOGAVIRUS TROPISM FOR BONES, JOINTS, AND CNS
    Mark Heise; Fiscal Year: 2001
    Togavirus infection of humans is characterized by acute and persistent arthritis/arthralgia, as well as viral encephalitis. Infection of adult mice with S.A...
  17. TOGAVIRUS TROPISM FOR BONES, JOINTS, AND CNS
    Mark Heise; Fiscal Year: 2002
    Togavirus infection of humans is characterized by acute and persistent arthritis/arthralgia, as well as viral encephalitis. Infection of adult mice with S.A...
  18. DEFINITION OF THE CHRONIC EPSTEIN-BARR VIRUS SYNDROME
    James Jones; Fiscal Year: 1990
    ..end, patients who have had varying combinations of pharyngitis, lymphadenopathy, headache, fatigue, myalgia, arthralgia, neuralgia, paresthesis, depression and dyslogia for over two years, and four controls--unrelated individuals ..
  19. Chimeric Alphavirus Vaccines for Chikungunya
    Scott Weaver; Fiscal Year: 2009
    ..is an emerging, mosquito-borne alphavirus and potential biological weapon that has caused debilitating, chronic arthralgia in at least 2 million persons in Asia and Africa since 2005...
  20. Chimeric Alphavirus Vaccines for Chikungunya
    Scott C Weaver; Fiscal Year: 2010
    ..is an emerging, mosquito-borne alphavirus and potential biological weapon that has caused debilitating, chronic arthralgia in at least 2 million persons in Asia and Africa since 2005...
  21. Development of a Novel, Chimeric Chikungunya Vaccine
    Richard Kinney; Fiscal Year: 2009
    ..mosquito-borne alphavirus and potential biological weapon that has caused debilitating and often chronic arthralgia in at least 2 million persons during the past 2 years, was recently placed on the NIAID list of priority ..
  22. Development of a Novel, Chimeric Chikungunya Vaccine
    Richard Kinney; Fiscal Year: 2009
    ..mosquito-borne alphavirus and potential biological weapon that has caused debilitating and often chronic arthralgia in at least 2 million persons during the past 2 years, was recently placed on the NIAID list of priority ..
  23. Acupuncture and aromatase inhibitor ralated arthralgia
    Jun Mao; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Arthralgia, joint pain, is emerging as a major source of symptom burden in postmenopausal breast cancer survivors receiving Aromatase Inhibitors (AIs) as adjuvant therapy...
  24. Acupuncture and aromatase inhibitor ralated arthralgia
    Jun J Mao; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Arthralgia, joint pain, is emerging as a major source of symptom burden in postmenopausal breast cancer survivors receiving Aromatase Inhibitors (AIs) as adjuvant therapy...
  25. Characterization of alphavirus infection receptors
    William Klimstra; Fiscal Year: 2009
    ..are arthropod-vectored viruses that can cause human diseases ranging from mild febrile illness to severe arthralgia or fatal encephalitis...
  26. Characterization of alphavirus infection receptors
    William B Klimstra; Fiscal Year: 2009
    ..are arthropod-vectored viruses that can cause human diseases ranging from mild febrile illness to severe arthralgia or fatal encephalitis...
  27. MOLECULAR IMMUNE RESPONSE DETERMINANTS OF RUBELLA VIRUS
    Jerry Wolinsky; Fiscal Year: 1993
    ..and pathological manifestations of the congenital rubella syndrome, progressive rubella panencephalitis, vaccine arthralgia and perhaps rheumatoid arthritis and multiple sclerosis...
  28. MOLECULAR IMMUNE RESPONSE DETERMINANTS OF RUBELLA VIRUS
    Jerry Wolinsky; Fiscal Year: 1990
    ..and pathological manifestations of the congenital rubella syndrome, progressive rubella panencephalitis, vaccine arthralgia and perhaps rheumatoid arthritis and multiple sclerosis...
  29. COMPUTERIZED THERMOGRAPHY OF CRANIOMANDIBULAR DISORDERS
    BARTON GRATT; Fiscal Year: 1990
    ..be able to distinguish between normal subjects and patients having internal derangements, osteoarthritis, or arthralgia of the TMJ; 2...
  30. PAIN SENSITIVITY AND THE DEVELOPMENT OF TEMPOROMANDIBULAR DISORDERS
    W Maixner; Fiscal Year: 2000
    ..We established that TMD patients who have muscle pain (myalgia) with or without joint pain (arthralgia) exhibit enhanced perceptual responses to quantitative noxious stimuli compared to age-and gender-matched ..
  31. PAIN SENSITIVITY AND THE DEVELOPMENT OF TEMPOROMANDIBULAR DISORDERS
    W Maixner; Fiscal Year: 2001
    ..We established that TMD patients who have muscle pain (myalgia) with or without joint pain (arthralgia) exhibit enhanced perceptual responses to quantitative noxious stimuli compared to age-and gender-matched ..
  32. Mechanisms of Pain Caused by Disruption of Microtubles
    Jon Levine; Fiscal Year: 2004
    ..primarily by the development of a painful peripheral neuropathy characterized by paresthesias, myalgia and arthralgia. Similar dose-limiting painful neuropathies are produced by other microtubule-disrupting chemotherapeutic drugs, ..
  33. Mechanisms of Pain Caused by Disruption of Microtubles
    Jon Levine; Fiscal Year: 2003
    ..primarily by the development of a painful peripheral neuropathy characterized by paresthesias, myalgia and arthralgia. Similar dose-limiting painful neuropathies are produced by other microtubule-disrupting chemotherapeutic drugs, ..
  34. Mechanisms of Pain Caused by Disruption of Microtubles
    Jon Levine; Fiscal Year: 2001
    ..primarily by the development of a painful peripheral neuropathy characterized by paresthesias, myalgia and arthralgia. Similar dose-limiting painful neuropathies are produced by other microtubule-disrupting chemotherapeutic drugs, ..
  35. Risk Factors for Onset and Persistence of TMD
    William Maixner; Fiscal Year: 2010
    Risk factors for onset and persistence of TMD: Myogenous temporomandibular disorder (TMD), with or without arthralgia, ranks second only to headache as the clinical condition most likely to cause craniofacial pain and dysfunction in the ..
  36. Risk Factors for Onset and Persistence of TMD
    William Maixner; Fiscal Year: 2005
    Risk factors for onset and persistence of TMD: Myogenous temporomandibular disorder (TMD), with or without arthralgia, ranks second only to headache as the clinical condition most likely to cause craniofacial pain and dysfunction in the ..
  37. Risk Factors for Onset and Persistence of TMD
    William Maixner; Fiscal Year: 2009
    Risk factors for onset and persistence of TMD: Myogenous temporomandibular disorder (TMD), with or without arthralgia, ranks second only to headache as the clinical condition most likely to cause craniofacial pain and dysfunction in the ..
  38. Risk Factors for Onset and Persistence of TMD
    William Maixner; Fiscal Year: 2007
    Risk factors for onset and persistence of TMD: Myogenous temporomandibular disorder (TMD), with or without arthralgia, ranks second only to headache as the clinical condition most likely to cause craniofacial pain and dysfunction in the ..
  39. Risk Factors for Onset and Persistence of TMD
    William Maixner; Fiscal Year: 2006
    Risk factors for onset and persistence of TMD: Myogenous temporomandibular disorder (TMD), with or without arthralgia, ranks second only to headache as the clinical condition most likely to cause craniofacial pain and dysfunction in the ..
  40. Risk Factors for Onset and Persistence of TMD
    William Maixner; Fiscal Year: 2010
    Risk factors for onset and persistence of TMD: Myogenous temporomandibular disorder (TMD), with or without arthralgia, ranks second only to headache as the clinical condition most likely to cause craniofacial pain and dysfunction in the ..
  41. Risk Factors for Onset and Persistence of TMD
    William Maixner; Fiscal Year: 2010
    Risk factors for onset and persistence of TMD: Myogenous temporomandibular disorder (TMD), with or without arthralgia, ranks second only to headache as the clinical condition most likely to cause craniofacial pain and dysfunction in the ..
  42. PILOT--DNA AND LIPID INDUCE TH1 MEDIATED PULMONARY INFLAMMATION
    FRITS VAN GINKEL; Fiscal Year: 2002
    ..The symptoms observed include fever, myalgia and arthralgia, occurring at six hours with full recovery between 24-48 hours after the administration of DNA/lipid 67 ..
  43. Novel regulatory role of cryopyrin in inflammation
    Harold Hoffman; Fiscal Year: 2004
    ..syndome (FCAS) is an autosomal dominant disorder characterized by recurrent episodes of rash, fever, and arthralgia following generalized exposure to cold...
  44. Novel regulatory role of cryopyrin in inflammation
    Harold Hoffman; Fiscal Year: 2005
    ..syndome (FCAS) is an autosomal dominant disorder characterized by recurrent episodes of rash, fever, and arthralgia following generalized exposure to cold...
  45. Structural Correlates of Knee Pain
    David Felson; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  46. RHEUMATOLOGY TRAINING GRANT
    David Felson; Fiscal Year: 2008
    ..The faculty provide a strong and experienced approach and will devote their talents to the training grant. [unreadable] [unreadable] [unreadable]..
  47. Relation of Alignment and Other Risk Factors to Knee OA
    David Felson; Fiscal Year: 2008
    ....
  48. Multicenter Osteoarthritis Study (MOST) Renewal
    David Felson; Fiscal Year: 2008
    ..Also, MOST will provide the best understanding yet of the relation between changes in knee structures and their effects on pain and function, providing structural targets for treatment. ..
  49. RHEUMATOLOGY TRAINING GRANT
    David Felson; Fiscal Year: 2007
    ..The faculty provide a strong and experienced approach and will devote their talents to the training grant. [unreadable] [unreadable] [unreadable]..
  50. NIAMS MULTIDISCIPLINARY CLINICAL RESEARCH CENTER
    David Felson; Fiscal Year: 2008
    ..An administrative unit will provide oversight to ensure that these projects are successfully accomplished and that core resources for support of these and other projects are allocated efficiently. ..
  51. MULTICENTER OSTEOARTHRITIS STUDY (MOST)
    David Felson; Fiscal Year: 2007
    ..abstract_text> ..
  52. Relation of Alignment and Other Risk Factors to Knee OA
    David Felson; Fiscal Year: 2009
    ....
  53. Strutural Correlates of Knee Pain
    David Felson; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  54. THE FRAMINGHAM OSTEOARTHRITIS STUDY
    David Felson; Fiscal Year: 2004
    ....
  55. THE FRAMINGHAM OSTEOARTHRITIS STUDY
    David Felson; Fiscal Year: 2003
    ....
  56. Relation of Alignment and Other Risk Factors to Knee OA
    David Felson; Fiscal Year: 2007
    ....
  57. CLINICAL RESEARCH TRAINING PROGRAM
    David Felson; Fiscal Year: 2004
    ..Fourth, we will integrate residents in training into the CREST program to develop an interest in clinical research at an early stage of training. ..
  58. THE FRAMINGHAM OSTEOARTHRITIS STUDY
    David Felson; Fiscal Year: 2005
    ....
  59. Relation of Alignment and Other Risk Factors to Knee OA
    DAVID TOBIN FELSON; Fiscal Year: 2010
    ....
  60. THE FRAMINGHAM OSTEOARTHRITIS STUDY
    David Felson; Fiscal Year: 2000
    ....
  61. Structural Correlates of Knee Pain
    David Felson; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  62. Relation of Alignment and Other Risk Factors to Knee OA
    David Felson; Fiscal Year: 2006
    ....
  63. (BOAMRI) Biomarkers in Osteoarthritis MRI Studies
    David Felson; Fiscal Year: 2006
    ..Use of validated biomarkers will greatly accelerate therapeutic development for this pressing public health concern. ..
  64. Multicenter Osteoarthritis Study (MOST) Renewal
    David Felson; Fiscal Year: 2008
    ..Also, MOST will provide the best understanding yet of the relation between changes in knee structures and their effects on pain and function, providing structural targets for treatment. ..
  65. THE FRAMINGHAM OSTEOARTHRITIS STUDY
    David Felson; Fiscal Year: 2002
    ....
  66. PARAFUNCTIONAL ACTIVITY AND TEMPOROMANDIBULAR DISORDERS
    Alan Glaros; Fiscal Year: 2002
    ....
  67. Molecular Mechanisms in Arterial Calcification
    Robert Terkeltaub; Fiscal Year: 2009
    ....
  68. Determinants and risks of use and overuse of expensive oncology drugs
    Dawn Hershman; Fiscal Year: 2008
    ..We propose to use the linked Surveillance, Epidemiology and End Results (SEER)-Medicare database to evaluate several important new costly therapies for their patterns of "appropriate use", "over-use", benefits and toxicities ..
  69. Chondrocyte S100/Calgranulins and RAGE in Osteoarthritis
    Robert Terkeltaub; Fiscal Year: 2008
    ..Completion of the work will reveal new potential targets for therapeutic intervention in OA by disconnecting inflammation from deleterious alteration of chondrocyte differentiation and function. ..
  70. Cooperative Lifestyle Intervention Program
    WALTER REJESKI; Fiscal Year: 2008
    ..Analyses will also be conducted to determine whether changes in the primary outcome are mediated by changes in constructs from social cognitive theory. ..
  71. Chondrocyte S100/Calgranulins and RAGE in Osteoarthritis
    Robert Terkeltaub; Fiscal Year: 2007
    ..Completion of the work will reveal new potential targets for therapeutic intervention in OA by disconnecting inflammation from deleterious alteration of chondrocyte differentiation and function. ..
  72. Estrogenic Regulation of Inflammation Related to TMJD
    Phillip Kramer; Fiscal Year: 2003
    ..The function of estrogen receptors ER alpha and/or ER beta will be directly addressed pharmacologically (e.g., antiestrogen) and through mutation studies of the Fc gamma RIIIA promoter. ..
  73. Chondrocyte S100/Calgranulins and RAGE in Osteoarthritis
    Robert Terkeltaub; Fiscal Year: 2006
    ..Completion of the work will reveal new potential targets for therapeutic intervention in OA by disconnecting inflammation from deleterious alteration of chondrocyte differentiation and function. ..
  74. Estrogenic LXR Alpha Response /Cholesterol Homeostasis
    Phillip Kramer; Fiscal Year: 2003
    ..abstract_text> ..
  75. Cooperative Lifestyle Intervention Program
    WALTER REJESKI; Fiscal Year: 2006
    ..Analyses will also be conducted to determine whether changes in the primary outcome are mediated by changes in constructs from social cognitive theory. ..
  76. Estrogenic Regulation of Inflammation Related to TMJD
    Phillip Kramer; Fiscal Year: 2006
    ..The function of estrogen receptors ER alpha and/or ER beta will be directly addressed pharmacologically (e.g., antiestrogen) and through mutation studies of the Fc gamma RIIIA promoter. ..
  77. HARVARD PEDIATRIC BRAIN TUMOR CENTER
    Mark Kieran; Fiscal Year: 2003
    ..David Louis). In summary, we will bring the full thrust of a Comprehensive Cancer Center and the full services of a pediatric center to enhance the Consortium and our mutual missions. ..
  78. Cooperative Lifestyle Intervention Program
    WALTER REJESKI; Fiscal Year: 2005
    ..Analyses will also be conducted to determine whether changes in the primary outcome are mediated by changes in constructs from social cognitive theory. ..
  79. Estrogenic Regulation of Inflammation Related to TMJD
    Phillip Kramer; Fiscal Year: 2004
    ..The function of estrogen receptors ER alpha and/or ER beta will be directly addressed pharmacologically (e.g., antiestrogen) and through mutation studies of the Fc gamma RIIIA promoter. ..
  80. Xenogen's IVIS 100 Imaging System
    Mark Kieran; Fiscal Year: 2004
    ..This luciferase-based technology affords a superior method to achieve this aim. ..
  81. PTHRP 1 to 173 IN CHONDROCYTES
    Robert Terkeltaub; Fiscal Year: 2004
    ..Completion of these studies will indicate not only how PTHrP 1-173 can modulate OA, but also how functional properties of the PTHrP 1-173 C-terminal 140-173 domain can be harnessed to promote cartilage repair. ..
  82. NPP1 and Molecular Mechanisms in Artery Calcification
    Robert Terkeltaub; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  83. The Relationship of n-3 Fatty Acids with Pain and Synovium in knee OA
    Kristin Baker; Fiscal Year: 2007
    ..It is a major public health issue with substantial economic impact that will increase as the population ages. Individuals with the disease are eager for nonpharmacological treatments such as a nutrition intervention. ..
  84. NPP1 and Molecular Mechanisms in Artery Calcification
    Robert Terkeltaub; Fiscal Year: 2004
    ..Completion of these studies will link alterations in VSMC PPi metabolism with modulation of oxidant stress and chemokine responses pertinent to pathologic calcification in both degenerative disorders and atherosclerosis. ..
  85. Optimizing Mobility in Elders with Knee Osteoarthritis: Gait and Power Training
    Neil Segal; Fiscal Year: 2007
    ..This substantial commitment will enhance training and research productivity, enabling the candidate to become an independent investigator who will advance physical function in older adults. ..
  86. Predictors and Consequences of Subchondral Bone Attrition in Osteoarthritis
    Tuhina Neogi; Fiscal Year: 2007
    ....
  87. Predictors and Consequences of Subchondral Bone Attrition in Osteoarthritis
    Tuhina Neogi; Fiscal Year: 2008
    ....
  88. ANK and Joint Ankylosis in Spondylitis
    Robert Terkeltaub; Fiscal Year: 2007
    ..These studies will identify novel targets for enthesopathic bone fusion in spondyloarthritis. ..
  89. Chondrocyte S100/Calgranulins and RAGE in Osteoarthritis
    Robert Terkeltaub; Fiscal Year: 2009
    ..Completion of the work will reveal new potential targets for therapeutic intervention in OA by disconnecting inflammation from deleterious alteration of chondrocyte differentiation and function. ..
  90. PTHRP 1 to 173 IN CHONDROCYTES
    Robert Terkeltaub; Fiscal Year: 2002
    ..Completion of these studies will indicate not only how PTHrP 1-173 can modulate OA, but also how functional properties of the PTHrP 1-173 C-terminal 140-173 domain can be harnessed to promote cartilage repair. ..
  91. Cooperative Lifestyle Intervention Program
    WALTER REJESKI; Fiscal Year: 2009
    ..Analyses will also be conducted to determine whether changes in the primary outcome are mediated by changes in constructs from social cognitive theory. ..
  92. Mechanics of non-contact ACL injuries in female athletes
    Christopher Powers; Fiscal Year: 2006
    ..abstract_text> ..
  93. Transglutaminase 2 in Arterial Calcification and Atherosclerosis
    Robert Terkeltaub; Fiscal Year: 2008
    ..Completion of these studies will delineate the potential for modulation of arterial TG2 as a therapy to suppress artery calcification or atherosclerotic lesion progression. ..
  94. Cooperative Lifestyle Intervention Program
    WALTER REJESKI; Fiscal Year: 2007
    ..Analyses will also be conducted to determine whether changes in the primary outcome are mediated by changes in constructs from social cognitive theory. ..
  95. NPP1 and Molecular Mechanisms in Artery Calcification
    Robert Terkeltaub; Fiscal Year: 2005
    ..Completion of these studies will link alterations in VSMC PPi metabolism with modulation of oxidant stress and chemokine responses pertinent to pathologic calcification in both degenerative disorders and atherosclerosis. ..
  96. Transglutaminase 2 in Arterial Calcification and Atherosclerosis
    Robert Terkeltaub; Fiscal Year: 2009
    ..Completion of these studies will delineate the potential for modulation of arterial TG2 as a therapy to suppress artery calcification or atherosclerotic lesion progression. ..
  97. PARAFUNCTIONAL ACTIVITY AND TEMPOROMANDIBULAR DISORDERS
    Alan Glaros; Fiscal Year: 2000
    ....
  98. PTHRP 1 to 173 IN CHONDROCYTES
    Robert Terkeltaub; Fiscal Year: 2001
    ..Completion of these studies will indicate not only how PTHrP 1-173 can modulate OA, but also how functional properties of the PTHrP 1-173 C-terminal 140-173 domain can be harnessed to promote cartilage repair. ..