- Defining the safe working zones using the minimally invasive lateral retroperitoneal transpsoas approach: an anatomical study
Juan S Uribe
Department of Neurological Surgery, University of South Florida, Tampa, Florida 33606, USA
J Neurosurg Spine 13:260-6. 2010
..The authors undertook this anatomical cadaveric dissection study to define the anatomical safe zones relative to the disc spaces for prevention of nerve injuries during the lateral retroperitoneal transpsoas approach...
- Surgical complications of posterior lumbar interbody fusion with total facetectomy in 251 patients
Department of Orthopaedic Surgery, Osaka Rosai Hospital, Osaka, Japan
J Neurosurg Spine 4:304-9. 2006
..The purpose of the present study was to examine rates of intraoperative and postoperative complications of PLIF using a large number of cases with uniform instrumentation and a uniform fusion technique...
- Direct lateral lumbar interbody fusion for degenerative conditions: early complication profile
Reginald Q Knight
Orthopedics International Spine, Kirkland, WA, USA
J Spinal Disord Tech 22:34-7. 2009
..Adverse events: new complaints and increasing length of stay limit early mobilization and require consultation with other physicians or reoperation. These formed the focus of the study...
- Biology of lumbar spine fusion and use of bone graft substitutes: present, future, and next generation
S D Boden
Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, Georgia 30033, USA
Tissue Eng 6:383-99. 2000
..This strategy of local gene therapy may provide a basis for the next generation of bone graft substitutes...
- Radiation exposure during fluoroscopically assisted pedicle screw insertion in the lumbar spine
D P Jones
Christchurch Hospital, New Zealand
Spine (Phila Pa 1976) 25:1538-41. 2000
..CONCLUSIONS: The source-superior position is the preferred position for pedicle screw screening if a working space is required. Patient exposure is minimized, and surgeon dose is well within current recommendations...
- Extreme lateral interbody fusion approach for isolated thoracic and thoracolumbar spine diseases: initial clinical experience and early outcomes
Isaac O Karikari
Division of Neurosurgery, Duke University Medical Center, Durham, NC 27710, USA
J Spinal Disord Tech 24:368-75. 2011
..Retrospective review of prospective collected data on 22 patients...
- Complications of lateral plating in the minimally invasive lateral transpsoas approach
Tien V Le
Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida 33606, USA
J Neurosurg Spine 16:302-7. 2012
..Three cases of hardware failure and 3 cases of vertebral body (VB) fractures associated with lateral plate placement are reported. The authors also review the literature pertaining to lateral plates and related complications...
- Recurrent low back pain and early disc degeneration in the young
J J Salminen
Department of Physical Medicine and Rehabilitation, University Hospital of Turku, Finland
Spine (Phila Pa 1976) 24:1316-21. 1999
- Vertebral endplate signal changes (Modic change): a systematic literature review of prevalence and association with non-specific low back pain
Tue Secher Jensen
The Back Research Center, Lindevej 5, Ringe, Denmark
Eur Spine J 17:1407-22. 2008
..0 to 19.9. This systematic review shows that VESC is a common MRI-finding in patients with non-specific LBP and is associated with pain. However, it should be noted that VESC may be present in individuals without LBP...
- Vascular injury in anterior lumbar surgery
J K Baker
Center for Spinal Disorders, Baylor College of Medicine, Houston, Texas
Spine (Phila Pa 1976) 18:2227-30. 1993
..abstract truncated at 250 words)..
- Health-related quality of life assessment by the EuroQol-5D can provide cost-utility data in the field of low-back surgery
Tore K Solberg
Department of Neurosurgery, University Hospital of North Norway, 9038, Tromsø, Norway
Eur Spine J 14:1000-7. 2005
..Our results indicate that the EQ-5D is useful for estimating health state values and for monitoring outcome of patients undergoing low-back surgery. Hence, this instrument would provide valid data for cost-utility analyses...
- Complications of posterior cervical plating
J G Heller
Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia, USA
Spine (Phila Pa 1976) 20:2442-8. 1995
..This study finds the risk of lateral mass screw insertion to be considerably less than predicted in vitro. The present study reports other complications that were not predicted in laboratory studies...
- Transplantation of mesenchymal stem cells in a canine disc degeneration model
Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa, 259 1193, Japan
J Orthop Res 26:589-600. 2008
..The results of this study suggest that MSC transplantation may contribute to the maintenance of IVD immune privilege by the differentiation of transplanted MSCs into cells expressing FasL...
- Diagnostic evaluation of low back pain with emphasis on imaging
Jeffrey G Jarvik
Department of Radiology, University of Washington, Seattle, Washington 98195, USA
Ann Intern Med 137:586-97. 2002
..To review evidence on the diagnostic accuracy of clinical information and imaging for patients with low back pain in primary care settings...
- Association between the -1562 C/T polymorphism of matrix metalloproteinase-9 gene and lumbar disc disease in the young adult population in North China
Zheng ming Sun
Department of Orthopaedics of the First Affiliated Hospital, Medical School, Xi an Jiaotong University, Xi an, China
Connect Tissue Res 50:181-5. 2009
..These results indicated that the -1562C/T polymorphism of the MMP-9 gene is associated with a high risk of degenerative disc disease in the young adult population in North China...
- Genetic risk factors for lumbar disc disease
Department of Medical Biochemistry, University of Oulu, Finland
Ann Med 34:42-7. 2002
..In addition, disc degeneration has been shown to be related to an aggrecan gene polymorphism, a vitamin D receptor and matrix metalloproteinase-3 gene alleles...
- Lumbar fusion outcomes stratified by specific diagnostic indication
Steven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA
Spine J 9:13-21. 2009
..Diagnostic specificity beyond the symptom of low back pain or the presence of lumbar degeneration needs to be delineated such that outcomes data can be effectively translated into clinical decision making or evidence-based guidelines...
- The value of fat saturation sequences and contrast medium administration in MRI of degenerative disease of the posterior/perispinal elements of the lumbosacral spine
Department of Neuroradiology, San Paolo Hospital, Bari, Italy
Eur Radiol 17:523-31. 2007
- Atherosclerosis and disc degeneration/low-back pain--a systematic review
L I Kauppila
Terveystalo Healthcare, Helsinki, Finland
Eur J Vasc Endovasc Surg 37:661-70. 2009
..The diminished blood flow could result in various back problems. The aim of this systematic literature review was to assess associations between atherosclerosis and disc degeneration (DD) or low-back pain (LBP)...
- Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science
Orthopaedic University Hospital Balgrist, Zurich, Switzerland
Spine (Phila Pa 1976) 27:2631-44. 2002
..A histologic study on age-related changes of the human lumbar intervertebral disc was conducted...
- Major complications in revision adult deformity surgery: risk factors and clinical outcomes with 2- to 7-year follow-up
Samuel K Cho
Department of Orthopaedics, Mount Sinai School of Medicine, New York, NY, USA
Spine (Phila Pa 1976) 37:489-500. 2012
..Retrospective cohort comparative study...
- Vascular injury in elective anterior lumbosacral surgery
Kirkham B Wood
Massachusetts General Hospital, Department of Orthopaedics, Harvard Medical School, Boston, MA 02114, USA
Spine (Phila Pa 1976) 35:S66-75. 2010
- Postsurgical spinal magnetic resonance imaging with iterative decomposition of water and fat with echo asymmetry and least-squares estimation
Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
J Comput Assist Tomogr 35:16-20. 2011
..Here, we compared postsurgical spinal MRI with IDEAL versus chemical shift selective saturation (CHESS)...
- Intervertebral disc degeneration: the role of the mitochondrial pathway in annulus fibrosus cell apoptosis induced by overload
Division of Biomedical Sciences, University of California, Riverside, California 92521 0121, USA
Am J Pathol 164:915-24. 2004
..Our results from human samples, mouse models, and annulus fibrosus culture experiments demonstrate that the mechanical overload-induced IVD degeneration is mediated through the mitochondrial apoptotic pathway in IVD cells...
- Obesity and spine surgery: relation to perioperative complications
Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois, USA
J Neurosurg Spine 6:291-7. 2007
..The authors retrospectively assessed the prevalence of obesity in a cohort of patients undergoing thoracic and lumbar fusion and correlate the presence of obesity with the incidence of operative complications...
- Systematic review of randomized trials comparing lumbar fusion surgery to nonoperative care for treatment of chronic back pain
Sohail K Mirza
Center for Cost and Outcomes Research, and Department of Orthopedics and Sports Medicine, University of Washington, Seattle, WA 98104 2499, USA
Spine (Phila Pa 1976) 32:816-23. 2007
..Systematic review of randomized trials comparing surgical to nonsurgical treatment of discogenic back pain...
- Compensatory spinopelvic balance over the hip axis and better reliability in measuring lordosis to the pelvic radius on standing lateral radiographs of adult volunteers and patients
R P Jackson
Spine Surgery Service, North Kansas City Hospital, Missouri, USA
Spine (Phila Pa 1976) 23:1750-67. 1998
..Understanding the common and characteristically different compensations that occur with balance in these patients who had specific spinal disorders may help to improve their care...
- Diagnostic imaging practice guidelines for musculoskeletal complaints in adults-an evidence-based approach-part 3: spinal disorders
André E Bussières
Chiropractic Department, Universite du Quebec a Trois Rivieres, Quebec, Canada
J Manipulative Physiol Ther 31:33-88. 2008
..To develop evidence-based diagnostic imaging practice guidelines to assist chiropractors and other primary care providers in decision making for the appropriate use of diagnostic imaging for spinal disorders...
- United States trends in lumbar fusion surgery for degenerative conditions
Richard A Deyo
Department of Medicine, University of Washington, Seattle, Washington, USA
Spine (Phila Pa 1976) 30:1441-5; discussion 1446-7. 2005
..Retrospective cohort study using national sample administrative data...
- Aneurysmal bone cyst of spine: a review of literature
Orthopaedic and Traumatologic Surgery, Gabriele d Annunzio University, Chieti Scalo, Italy
Arch Orthop Trauma Surg 128:1145-7. 2008
..Children and young adults are most affected by spinal ABCs. We document a review of literature...
- Polymethylmethacrylate augmentation of pedicle screw for osteoporotic spinal surgery: a novel technique
Ming Chau Chang
Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Spine (Phila Pa 1976) 33:E317-24. 2008
A retrospective study to evaluate the clinical results of patients with osteoporosis and various spinal diseases treated surgically with polymethylmethacrylate (PMMA) augmented pedicle screw.
- 4- and 5-level anterior fusions of the cervical spine: review of literature and clinical results
German Scoliosis Center, Bad Wildungen, Hessen, Germany
Eur Spine J 16:2055-71. 2007
..The discussion of our results are accompanied by a detailed review of literature, shedding light on the biomechanical challenges in multilevel cervical procedures and suggests conclusions...
- Dynesys fixation for lumbar spine degeneration
Department of Surgery, Neurosurgery, Kantonsspital Winterthur, Brauerstrasse 15, 8401 Winterthur, Switzerland
Neurosurg Rev 31:189-96. 2008
..Outcome data were not superior to conventional rigid fusion systems and had a considerable number of complications requiring revision surgery in 27.5% of cases...
- Complications related to osteobiologics use in spine surgery: a systematic review
Thomas E Mroz
Neurological Institute, Center for Spine Health, Departments of Orthopaedic and Neurological Surgery, The Cleveland Clinic, Cleveland, OH 44195, USA
Spine (Phila Pa 1976) 35:S86-104. 2010
- Posterior cervical arthrodesis and stabilization with a lateral mass plate. Clinical and computed tomographic evaluation of lateral mass screw placement and associated complications
A W Graham
Florida Fellowship in Reconstructive Spinal Surgery, Gainesville, USA
Spine (Phila Pa 1976) 21:323-8; discussion 329. 1996
..Radicular symptoms improved with screw removal in each case. The advantages of segmental fixation achieved with lateral mass plates and screws must be weighed against the risk of radiculopathy...
- Lumbar spine fusion in obese and morbidly obese patients
Department of Orthopedic Surgery, Detroit Receiving Hospital and University Health Center, Detroit, MI 48201, USA
Spine (Phila Pa 1976) 34:495-500. 2009
..Single-center retrospective study...
- Multilevel cervical fusion without plates, screws or autogenous iliac crest bone graft
Mehmet Nusret Demircan
GATA Haydarpasa Training Hospital, Department of Neurosurgery, Istanbul, Turkey
J Clin Neurosci 14:723-8. 2007
- A population-based study of spinal pain among 35-45-year-old individuals. Prevalence, sick leave, and health care use
S J Linton
Department of Occupational and Environmental Medicine, Orebro Medical Center, Sweden
Spine (Phila Pa 1976) 23:1457-63. 1998
..Gender differences exist in the pattern of sick leave and health care use, and a small proportion of those with pain consume very large amounts of the resources. Consequently, there is a need for early, effective, preventive treatments...
- MR imaging evaluation of the bone marrow and marrow infiltrative disorders of the lumbar spine
Department of Radiology, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, London, UK, HA7 4LP
Magn Reson Imaging Clin N Am 15:199-219, vi. 2007
..The appearances of infiltrative marrow disease are explained on the basis of marrow composition and whether disease causes proliferation, replacement, or depletion of normal marrow components...
- Factors associated with good outcome using lateral mass plate fixation
Department of Orthopedics and Traumatology, University of Crete, Medical School Heraklion, Crete, Greece
Orthopedics 27:1080-6. 2004
- Cutting-edge imaging of the spine
A Talia Vertinsky
Stanford University, Department of Radiology, Lucas Center, PS08, 1201 Welch Road, Stanford, CA 94305 5488, USA
Neuroimaging Clin N Am 17:117-36. 2007
..These new "cutting-edge" technologies have the potential to impact profoundly the ease and confidence of spinal disease interpretation and offer a more efficient diagnostic workup of patients suffering from spinal disease...
- Modern surgical treatment of primary aneurysmal bone cyst of the spine in children and adolescents
Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
J Pediatr Orthop 25:387-92. 2005
..The four-step approach to treatment of ABC of the spine with appropriate spinal instrumentation and fusion is recommended for successful treatment of this aggressive lesion...
- T1- and T2-weighted fast spin-echo imaging of the brachial plexus and cervical spine with IDEAL water-fat separation
Scott B Reeder
Department of Radiology, University of Wisconsin, Madison, Wisconsin 53792 3252, USA
J Magn Reson Imaging 24:825-32. 2006
- Radiographic anomalies that may alter chiropractic intervention strategies found in a New Zealand population
J Manipulative Physiol Ther 28:375; author reply 375-6. 2005
- Lateral mass screw-rod fixation of the cervical spine: a prospective clinical series with 1-year follow-up
H Gordon Deen
Department of Neurosurgery, Mayo Clinic Jacksonville, Jacksonville, FL 32224, USA
Spine J 3:489-95. 2003
- Influence of smoking on the health status of spinal patients: the National Spine Network database
Molly T Vogt
Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Spine (Phila Pa 1976) 27:313-9. 2002
..Multicenter, cross-sectional analysis of data from the National Spine Network...
- Advanced imaging of the spine in small animals
Ronaldo C da Costa
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp Street, Columbus, OH 43210 1089, USA
Vet Clin North Am Small Anim Pract 40:765-90. 2010
..The CT and MRI features of common spinal diseases are discussed and illustrated...
- Outcome of pedicle subtraction osteotomies for fixed sagittal imbalance of multiple etiologies: a retrospective review of 140 patients
Ki Tack Kim
Department of Orthopaedic Surgery, School of Medicine, Kyung Hee University, Seoul, Korea
Spine (Phila Pa 1976) 37:1667-75. 2012
..A retrospective study...
- Spinal aneurysmal bone cyst causing acute cord compression without vertebral collapse: CT and MRI findings
Monica S M Chan
Department of Diagnostic Radiology, Tuen Mun Hospital, Tsing Chung Koon Road, Tuen Mun, New Territories, Hong Kong
Pediatr Radiol 32:601-4. 2002
..This case illustrates a less frequently recognised mechanism of acute spinal cord compression by ABC...
- The prevalence of and specific risk factors for venous thromboembolic disease following elective spine surgery
Jason M Sansone
Department of Orthopedics and Rehabilitation, University of Wisconsin, Madison, WI 53792, USA
J Bone Joint Surg Am 92:304-13. 2010
..We sought to investigate the prevalence of thromboembolism as well as the efficacy and complications of various prophylactic measures in a population of patients who had undergone elective spine surgery...
- An evidence-based clinical guideline for the use of antithrombotic therapies in spine surgery
Christopher M Bono
North American Spine Society
Spine J 9:1046-51. 2009
..The goal of the guideline recommendations was to assist in delivering optimum, efficacious treatment with the goal of preventing thromboembolic events...
- Aggressive "benign" primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor
James S Harrop
Department of Neurological Surgery and Orthopedic Surgery, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
Spine (Phila Pa 1976) 34:S39-47. 2009
..Clinically based systematic review...
- Retrograde ejaculation after anterior lumbar spine surgery
Emily M Lindley
Department of Orthopaedics, The Spine Center, University of Colorado Denver, Anschutz Medical Campus, Denver, CO, USA
Spine (Phila Pa 1976) 37:1785-9. 2012
..A retrospective cohort study...
- Correlation of diffusion in lumbar intervertebral disks with occlusion of lumbar arteries: a study in adult volunteers
Department of Diagnostic Radiology, Oulu University Hospital, Kajaanintie 50, 90220 Oulu, Finland
Radiology 221:779-86. 2001
..To evaluate the correlation of the diffusion values in lumbar intervertebral disks with lumbar artery status and the degree of disk degeneration...
- Aneurysmal bone cyst of the cervical spine (2008:7b)
Institute of Diagnostic and Interventional Radiology and Nuclear Medicine, BG Kliniken Bergmannsheil, Ruhr University Bochum, Buerkle de la Camp Platz 1, 44789 Bochum, Germany
Eur Radiol 18:2356-60. 2008
..The typical macroscopic and histological findings were present. The tumor was resected en bloc, after which the patient underwent adjuvant radiation therapy. The patient made a complete recovery...
- Obesity and spine surgery: reassessment based on a prospective evaluation of perioperative complications in elective degenerative thoracolumbar procedures
Department of Neurosurgery, Thomas Jefferson University Medical Center, Philadelphia, PA 19107, USA
Spine J 10:581-7. 2010
..The correlation between obesity and incidence of complications in spine surgery is unclear, with some reports suggesting linear relationships between body mass index (BMI) and complication incidence and others noting no relationship...
- Symptomatic intraspinal pneumocoele resulting from closed head injury
Department of Neurosurgery, Royal Victoria Hospital, Belfast, Northern Ireland, UK
Br J Neurosurg 17:248-9. 2003
..Intraspinal pneumocoele is rarely associated with closed head injury. We describe a case of intra-spinal pneumocoele following a closed head injury. We believe this to be the first case presenting with radicular symptoms...
- Treatment of traumatic cervical spine instability with interbody fusion cages: a prospective controlled study with a 2-year follow-up
Centrum für Muskuloskeletale Chirurgie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
Injury 36:B27-35. 2005
..The purpose of this prospective cohort study was to define indications and analyze the clinical and radiographic results of using interbody cages to surgically treat traumatic cervical spine instability...
- Anterior corpectomy with iliac bone fusion or discectomy with interbody titanium cage fusion for multilevel cervical degenerated disc disease
Shiuh Lin Hwang
Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
J Spinal Disord Tech 20:565-70. 2007
..Clinical and radiologic study evaluating the outcome after anterior corpectomy with iliac bone fusion compared with discectomy with interbody titanium cage fusion for multilevel cervical degenerated disc disease...
- The characteristics of patient satisfaction measures
P L Hudak
Institute for Medical Sciences, University of Toronto, Toronto, ON, Canada
Spine (Phila Pa 1976) 25:3167-77. 2000
- [Experiences with six different intervertebral disc spacers for spondylodesis of the cervical spine]
Klinik für Neurochirurgie, Unfallkrankenhaus, Berlin
Orthopade 33:1290-9. 2004
..The PEEK spacer from Intromed can be implanted safely but shows a tendency for dislocation. Long-term results are yet to be reported...
- The Oswestry Disability Index
J C Fairbank
Nuffield Orthopaedic Centre, Oxford, United Kingdom
Spine (Phila Pa 1976) 25:2940-52; discussion 2952. 2000
..This review is based on publications using the ODI identified from the authors' personal databases, the Science Citation Index, and hand searches of Spine and current textbooks of spinal disorders...
- Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and finite-element study
J C Lotz
Department of Orthopaedic Surgery, University of California, San Francisco, California, USA
Spine (Phila Pa 1976) 23:2493-506. 1998
- Evidence for skeletal progenitor cells in the degenerate human intervertebral disc
Makarand V Risbud
Department of Orthopaedic Surgery and Graduate Program in Tissue Engineering and Regenerative Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
Spine (Phila Pa 1976) 32:2537-44. 2007
..To identify and characterize endogenous progenitor cell population from intervertebral disc...
- Histology and pathology of the human intervertebral disc
Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Oswestry, Shropshire SY10 7AG, United Kingdom
J Bone Joint Surg Am 88:10-4. 2006
..Whatever the initial cause, a change in the morphology of the tissue is likely to alter the physiologic and mechanical functioning of the tissue...
- Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs
J I Sive
Musculoskeletal Research Group, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
Mol Pathol 55:91-7. 2002
..To investigate the phenotype of cells in normal and degenerate intervertebral discs by studying the expression of molecules characteristic of chondrocytes in situ...
- Adjacent segment degeneration in the lumbar spine
Denver Spine Center, 1601 East 19th Avenue, Suite 4000, Denver, CO 80218, USA
J Bone Joint Surg Am 86:1497-503. 2004
..A retrospective investigation was performed to determine the rates of degeneration and survival of the motion segments adjacent to the site of a posterior lumbar fusion...
- Roentgenographic analysis of posture in spinal osteoporotics
Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan
Spine (Phila Pa 1976) 16:750-6. 1991
..Low-back pain was highly associated with decreased lumbar lordosis and increased sacropelvic angle, suggesting that the sacroiliac joint was one of the causes of low-back pain...
- The Longitudinal Assessment of Imaging and Disability of the Back (LAIDBack) Study: baseline data
J J Jarvik
Department of Radiology, University of Washington, Seattle 98195, USA
Spine (Phila Pa 1976) 26:1158-66. 2001
..Prospective cohort study of randomly selected Veterans Affairs (VA) outpatients...
- Minimally invasive lumbar fusion
Kevin T Foley
Image Guided Surgery Research Center, Methodist Hospitals of Memphis, Semmes Murphey Clinic and the Department of Neurosurgery, University of Tennessee, Memphis 38104, USA
Spine (Phila Pa 1976) 28:S26-35. 2003
- ISSLS prize winner: repeated disc injury causes persistent inflammation
Jill A Ulrich
Orthopaedic Bioengineering Laboratory, Department of Orthopaedic Surgery, University of California at San Francisco, San Francisco, CA 94143 0514, USA
Spine (Phila Pa 1976) 32:2812-9. 2007
..An in vivo rat model of disc degeneration with emphasis on characterizing acute and chronic cytokine production...
- Pneumorrhachis of the entire spinal canal
M F Oertel
Department of Neurosurgery, University Hospital, School of Medicine, Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany
J Neurol Neurosurg Psychiatry 76:1036. 2005
- Acute hemorrhagic cyst of the ligamentum flavum
Department of Neurosurgery, San Giovanni Addolorata Hospital, Roma, Italy
J Spinal Disord Tech 20:536-8. 2007
..A case report and clinical discussion...
- A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration
Christine L Le Maitre
Division of Laboratory and Regenerative Medicine, School of Medicine, University of Manchester, Manchester, UK
Int J Exp Pathol 87:17-28. 2006
..This in vitro study has shown that the use of ex vivo gene transfer to degenerate disc tissue is a feasible therapy for the inhibition of IL-1-mediated events during disc degeneration...
- Are lumbar spine reoperation rates falling with greater use of fusion surgery and new surgical technology?
Brook I Martin
Department of Medicine, University of Washington, Seattle, WA, USA
Spine (Phila Pa 1976) 32:2119-26. 2007
..A retrospective analysis of population-based hospital discharge registry from all nonfederal acute care hospitals in Washington State...
- Restoration of disc height loss by recombinant human osteogenic protein-1 injection into intervertebral discs undergoing degeneration induced by an intradiscal injection of chondroitinase ABC
Department of Orthopedic Surgery, Rush Medical College at Rush University Medical Center, Chicago, IL 60612, USA
Spine (Phila Pa 1976) 32:1197-205. 2007
..In vivo study of the effect of an injection of recombinant human osteogenic protein-1 into degenerated discs induced by chondroitinase ABC...
- Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc
J A Hoyland
Tissue Injury and Repair Group, Research School in Clinical and Laboratory Sciences, Stopford Building, The University of Manchester, Oxford Road, Manchester M13 9PT, UK
Rheumatology (Oxford) 47:809-14. 2008
..To establish if IL-1 or TNF regulates matrix degradation in the non-degenerate or degenerate intervertebral disc (IVD)...
- Diagnostic accuracy and reliability of fine-cut CT scans with reconstructions to determine the status of an instrumented posterolateral fusion with surgical exploration as reference standard
Leah Y Carreon
Kenton D Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 32:892-5. 2007
..Accuracy of a diagnostic test referenced to the gold standard...
- Bone morphogenetic proteins and bone defects: a systematic review
Department of Biomedical Science and Human Oncology, University of Turin, Italy
Spine (Phila Pa 1976) 32:824-30. 2007
..A systematic review of scientific literature...
- The Dynesys lumbar spinal stabilization system: a preliminary report on positional magnetic resonance imaging findings
Woodend Hospital, Aberdeen, Scotland
Spine (Phila Pa 1976) 32:685-90. 2007
..We present the positional magnetic resonance imaging findings of a prospective case series of patients undergoing surgery with the Dynesys spinal stabilization device (Zimmer, Inc., Warsaw, IN)...
- Reverse transformation of Modic type 2 changes to Modic type 1 changes during sustained chronic low-back pain severity. Report of two cases and review of the literature
Laurence A G Marshman
Department of Spinal Surgery, University Hospital of North Tees, United Kingdom
J Neurosurg Spine 6:152-5. 2007
..Each type can change, with equal symptom-generating capacity. More representative imaging-pathological correlates are required to determine the precise nature of MT changes...
- Human disc degeneration is associated with increased MMP 7 expression
C L Le Maitre
Division of Regenerative Medicine, School of Medicine, University of Manchester, Manchester, M13 9PT, United Kingdom
Biotech Histochem 81:125-31. 2006
..Prolapsed discs showed more MMP 7 immunopositive cells compared to nondegenerated discs, but fewer than those seen in cases of severe degeneration...
- MRI follow-up of subchondral signal abnormalities in a selected group of chronic low back pain patients
Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, 00250, Helsinki, Finland
Eur Spine J 17:1300-8. 2008
..They seem to have a highly variable course. There appears to be a link between endplate lesions and subchondral signal abnormalities. Further study is needed to explain the contribution of these findings to low back symptoms...
- Reliability of the prospective data collection protocol of the Swedish Spine Register: test-retest analysis of 119 patients
Department of Orthopedics, Lund University Hospital Lund, SE 221 85 Sweden
Acta Orthop 77:662-9. 2006
..In a few years, it will produce useful clinical information just as arthroplasty registers have, but to permit proper interpretation of data in the future, the reliability of the protocol must be tested...
- Ultrasound imaging of the intervertebral disc
Anatomy Department, University of Bristol
Spine (Phila Pa 1976) 28:107-13. 2003
..In vitro ultrasound imaging of dog intervertebral discs was performed...
- Comparison of conventional versus minimally invasive extraperitoneal approach for anterior lumbar interbody fusion
Department of Orthopaedic Surgery, Leopold Franzens University, Anichstrasse 35, 6020 Innsbruck, Austria
Eur Spine J 13:425-31. 2004
..In addition, this approach showed significant improvement in postoperative back pain in comparison to the conventional approach for ALIF...
- Disc chondrocyte transplantation in a canine model: a treatment for degenerated or damaged intervertebral disc
Atlanta Medical Center, Atlanta, Georgia 30312, USA
Spine (Phila Pa 1976) 28:2609-20. 2003
..A dog model was used to investigate the hypothesis that autologous disc chondrocytes can be used to repair damaged intervertebral disc...
- Stability of posterior spinal instrumentation and its effects on adjacent motion segments in the lumbosacral spine
Department of Orthopaedic Surgery, Hokkaido University School of Medicine, Sapporo, Japan
Spine (Phila Pa 1976) 23:1550-8. 1998
- Collagen type I alpha1 Sp1 polymorphism, osteoporosis, and intervertebral disc degeneration in older men and women
S M F Pluijm
Institute for Research in Extramural Medicine EMGO Institute, VU University Medical Centre, Amsterdam, The Netherlands
Ann Rheum Dis 63:71-7. 2004
..To examine whether collagen type I alpha1 (COLIA1) Sp1 polymorphism is associated with osteoporosis and/or intervertebral disc degeneration in older people...
- Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis
A S Hilibrand
Department of Orthopaedic Surgery, University Hospitals Spine Institute, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
J Bone Joint Surg Am 81:519-28. 1999
- Circumferential lumbar spinal fusion with Brantigan cage versus posterolateral fusion with titanium Cotrel-Dubousset instrumentation: a prospective, randomized clinical study of 146 patients
Finn B Christensen
Spine Section, Department of Orthopedic Surgery, University Hospital of Aarhus, Denmark
Spine (Phila Pa 1976) 27:2674-83. 2002
..A prospective randomized clinical study with a 2-year follow-up period was conducted...
- Comparison of posterior and transforaminal approaches to lumbar interbody fusion
S C Humphreys
Center for Sports Medicine and Orthopaedics, Foundation for Research, Chattanooga, Tennesse 37404, USA
Spine (Phila Pa 1976) 26:567-71. 2001
..A study of the transforaminal lumbar interbody fusion and the posterior lumbar interbody fusion techniques was performed...
- Schmorl nodes of the thoracic and lumbar spine: radiographic-pathologic study of prevalence, characterization, and correlation with degenerative changes of 1,650 spinal levels in 100 cadavers
C W Pfirrmann
Department of Radiology, Veterans Affairs San Diego Healthcare System, 3350 La Jolla Village Dr, San Diego, CA 92161, USA
Radiology 219:368-74. 2001
..Geometric observations regarding the vertebral endplates support the concept that Schmorl nodes are caused by an abnormality of the discovertebral junction...
- The impact of adjacent level disc degeneration on health status outcomes following lumbar fusion
Thomas W Throckmorton
The Vanderbilt University Spine Center, Department of Orthopaedics and Rehabilitation, Nashville, Tennessee, USA
Spine (Phila Pa 1976) 28:2546-50. 2003
..A retrospective review of patient outcomes after lumbar spinal fusion...
- Rates of advanced spinal imaging and spine surgery
Jon D Lurie
Center for the Evaluative Clinical Sciences, Dartmouth Medical School, Hanover, New Hampshire, USA
Spine (Phila Pa 1976) 28:616-20. 2003
..Small area analysis...
- Single-level lumbar spine fusion: a comparison of anterior and posterior approaches
Ben B Pradhan
Department of Orthopaedic Surgery, UCLA School of Medicine, Los Angeles 90095 6902, USA
J Spinal Disord Tech 15:355-61. 2002
..This may in turn affect surgical outcome and hospital cost. However, both approaches to single-level lumbar fusion produce similar early fusion rates and clinical results. Revision fusions had poor early results regardless of approach...
- Relationships among selected measures of impairment, functional limitation, and disability in patients with cervical spine disorders
K M Hermann
The Therapy Center, College Station Medical Center, 1605 Rock Praire Rd, Ste 5, College Station, TX 77845, USA
Phys Ther 81:903-14. 2001
..A secondary purpose was to determine the influence of payment source and time since onset of symptoms on these same measures...
- 2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption
Institute of Pathology, University of Munich, Germany
Eur Spine J 11:308-20. 2002
..These findings implicate a leading function for MMPs in IVD degeneration resulting in the loss of normal disc function, eventually leading to low-back pain...
- Calcification of intervertebral discs in the dachshund: a radiographic study of 115 dogs at 1 and 5 years of age
Department of Small Animal Clinical Sciences, Norwegian College of Veterinary Medicine, Oslo, Norway
Acta Vet Scand 37:229-37. 1996
..6%) of the dogs in which calcified discs were not identified at 1 year of age. Of all dogs in which one or more calcified discs had disappeared during the study-period, signs of spinal disease were registered in 9 (75.0%)...
- In vivo stress measurement can predict pain on discography
D S McNally
Department of Anatomy, University of Bristol, UK
Spine (Phila Pa 1976) 21:2580-7. 1996
..017). CONCLUSIONS: Stress profilometry is an effective investigation of the mechanics of intervertebral discs in vivo. Discogenic pain is caused by changes in the pattern of loading of the posterolateral anulus or nucleus pulposus...
- Impact of degenerative spinal diseases on bone mineral density of the lumbar spine in elderly women
Department of Orthopedic Surgery, Tokyo University School of Medicine, Japan
Osteoporos Int 15:724-8. 2004
..The aim of this study is to determine whether the degree of degenerative spinal diseases is correlated with lumbar spine and femoral neck BMD...