postpartum hemorrhage

Summary

Summary: Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).

Top Publications

  1. pmc Incidence and predictors of severe obstetric morbidity: case-control study
    M Waterstone
    Department of Public Health Medicine, Guy's, King's College, and St Thomas's Hospitals Schools of Medicine and Dentistry, Capital House, London SE1 3QD
    BMJ 322:1089-93; discussion 1093-4. 2001
  2. ncbi Risk factors for postpartum hemorrhage: can we explain the recent temporal increase?
    Michael S Kramer
    Department of Pediatrics, Faculty of Medicine, McGill University, Montreal QC
    J Obstet Gynaecol Can 33:810-9. 2011
  3. doi The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries
    Brian T Bateman
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Anesth Analg 110:1368-73. 2010
  4. doi Community-based distribution of misoprostol for treatment or prevention of postpartum hemorrhage: cost-effectiveness, mortality, and morbidity reduction analysis
    Tori Sutherland
    Department of Obstetrics and Gynecology, Johns Hopkins School of Medicine, Baltimore, USA
    Int J Gynaecol Obstet 108:289-94. 2010
  5. pmc Where there are (few) skilled birth attendants
    Ndola Prata
    Bixby Center for Population, Health and Sustainability, University of California Berkeley, 229 University Hall, Berkeley, CA 94720 6390, USA
    J Health Popul Nutr 29:81-91. 2011
  6. doi Increasing trends in atonic postpartum haemorrhage in Ireland: an 11-year population-based cohort study
    J E Lutomski
    National Perinatal Epidemiology Centre, Cork University Maternity Hospital, Wilton, Cork, Ireland
    BJOG 119:306-14. 2012
  7. doi Maternal obesity and risk of postpartum hemorrhage
    Marie Blomberg
    Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    Obstet Gynecol 118:561-8. 2011
  8. ncbi Postpartum hemorrhage after vaginal birth: an analysis of risk factors
    Everett F Magann
    School of Women and Infants Health, King Edward Memorial Hospital, Perth, Australia
    South Med J 98:419-22. 2005
  9. doi Prevalence and risk factors of severe obstetric haemorrhage
    I Al-Zirqi
    Division of Obstetrics and Gynaecology, Rikshospitalet, Faculty of Medicine, University of Oslo, Oslo, Norway
    BJOG 115:1265-72. 2008
  10. doi Estimation of potential effects of improved community-based drug provision, to augment health-facility strengthening, on maternal mortality due to post-partum haemorrhage and sepsis in sub-Saharan Africa: an equity-effectiveness model
    Christina Pagel
    Clinical Operational Research Unit, Department of Mathematics, University College London, London, UK
    Lancet 374:1441-8. 2009

Detail Information

Publications299 found, 100 shown here

  1. pmc Incidence and predictors of severe obstetric morbidity: case-control study
    M Waterstone
    Department of Public Health Medicine, Guy's, King's College, and St Thomas's Hospitals Schools of Medicine and Dentistry, Capital House, London SE1 3QD
    BMJ 322:1089-93; discussion 1093-4. 2001
    ..Caesarean section quadruples the risk of morbidity. Development and evaluation of ways of predicting and reducing risk are required with particular emphasis paid on the management of haemorrhage and pre-eclampsia...
  2. ncbi Risk factors for postpartum hemorrhage: can we explain the recent temporal increase?
    Michael S Kramer
    Department of Pediatrics, Faculty of Medicine, McGill University, Montreal QC
    J Obstet Gynaecol Can 33:810-9. 2011
    To assess risk factors for postpartum hemorrhage (PPH) and the extent to which changes in those risk factors may explain the rising incidence of PPH recently reported from industrialized countries.
  3. doi The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries
    Brian T Bateman
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Anesth Analg 110:1368-73. 2010
    In this study, we sought to (1) define trends in the incidence of postpartum hemorrhage (PPH), and (2) elucidate the contemporary epidemiology of PPH focusing on risk factors and maternal outcomes related to this delivery complication.
  4. doi Community-based distribution of misoprostol for treatment or prevention of postpartum hemorrhage: cost-effectiveness, mortality, and morbidity reduction analysis
    Tori Sutherland
    Department of Obstetrics and Gynecology, Johns Hopkins School of Medicine, Baltimore, USA
    Int J Gynaecol Obstet 108:289-94. 2010
    To compare the cost-effectiveness of community-based distribution of misoprostol for prevention with misoprostol for treatment of postpartum hemorrhage (PPH).
  5. pmc Where there are (few) skilled birth attendants
    Ndola Prata
    Bixby Center for Population, Health and Sustainability, University of California Berkeley, 229 University Hall, Berkeley, CA 94720 6390, USA
    J Health Popul Nutr 29:81-91. 2011
    ..g. misoprostol, family planning, measurement of blood loss, and postpartum care) will increase the chance that women in the lowest economic quintiles will also benefit from global safe motherhood efforts...
  6. doi Increasing trends in atonic postpartum haemorrhage in Ireland: an 11-year population-based cohort study
    J E Lutomski
    National Perinatal Epidemiology Centre, Cork University Maternity Hospital, Wilton, Cork, Ireland
    BJOG 119:306-14. 2012
    ..To derive nationally representative incidence rates of postpartum haemorrhage (PPH), and to investigate trends associated with method of delivery, blood transfusion and morbidly adherent placenta (accreta, percreta and increta)...
  7. doi Maternal obesity and risk of postpartum hemorrhage
    Marie Blomberg
    Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    Obstet Gynecol 118:561-8. 2011
    To estimate whether maternal obesity was associated with an increased risk for postpartum hemorrhage more than 1,000 mL and whether there was an association between maternal obesity and causes of postpartum hemorrhage and mode of delivery.
  8. ncbi Postpartum hemorrhage after vaginal birth: an analysis of risk factors
    Everett F Magann
    School of Women and Infants Health, King Edward Memorial Hospital, Perth, Australia
    South Med J 98:419-22. 2005
    To determine, in a single tertiary obstetric hospital, the incidence of and risk factors for postpartum hemorrhage (PPH) after a vaginal birth.
  9. doi Prevalence and risk factors of severe obstetric haemorrhage
    I Al-Zirqi
    Division of Obstetrics and Gynaecology, Rikshospitalet, Faculty of Medicine, University of Oslo, Oslo, Norway
    BJOG 115:1265-72. 2008
    ..To determine the prevalence, causes, risk factors and acute maternal complications of severe obstetric haemorrhage...
  10. doi Estimation of potential effects of improved community-based drug provision, to augment health-facility strengthening, on maternal mortality due to post-partum haemorrhage and sepsis in sub-Saharan Africa: an equity-effectiveness model
    Christina Pagel
    Clinical Operational Research Unit, Department of Mathematics, University College London, London, UK
    Lancet 374:1441-8. 2009
    ....
  11. doi Postpartum hemorrhage: epidemiology, risk factors, and causes
    Yinka Oyelese
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Tennessee Institute of Fetal Maternal and Infant Health, University of Tennessee Health Sciences Center, Memphis, TN, USA
    Clin Obstet Gynecol 53:147-56. 2010
    b>Postpartum hemorrhage (PPH) is a leading cause of death and morbidity relating to pregnancy. Uterine atony is the leading cause of PPH, and trauma, including iatrogenic trauma, increases the risk for postpartum hemorrhage...
  12. pmc Multifaceted intervention to decrease the rate of severe postpartum haemorrhage: the PITHAGORE6 cluster-randomised controlled trial
    C Deneux-Tharaux
    INSERM, UMR S953, UPMC, Epidemiological Research Unit on Perinatal Health and Women s and Children s Health, Paris, France
    BJOG 117:1278-87. 2010
    ..We tested the hypothesis that a multifaceted intervention aimed at increasing the translation into practice of a protocol for early management of PPH, would reduce the incidence of severe PPH...
  13. doi Trends in postpartum hemorrhage: United States, 1994-2006
    William M Callaghan
    Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Obstet Gynecol 202:353.e1-6. 2010
    The purpose of this study was to estimate the incidence of postpartum hemorrhage (PPH) in the United States and to assess trends.
  14. doi A behavioral intervention to improve obstetrical care
    Fernando Althabe
    Institute of Clinical Effectiveness and Health Policy, Buenos Aires, Argentina
    N Engl J Med 358:1929-40. 2008
    ..Implementation of evidence-based obstetrical practices remains a significant challenge. Effective strategies to disseminate and implement such practices are needed...
  15. ncbi Uterine compression sutures: surgical management of postpartum hemorrhage
    R G Hayman
    Department of Obstetrics and Gynaecology, Derby City Hospital, Derby, United Kingdom
    Obstet Gynecol 99:502-6. 2002
    It has been estimated that worldwide, over 125,000 women die of postpartum hemorrhage each year...
  16. ncbi Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects
    O S Tang
    Department of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong SAR, China
    Int J Gynaecol Obstet 99:S160-7. 2007
    ..abortion, cervical priming, the management of miscarriage, induction of labor and the management of postpartum hemorrhage. It can be given orally, vaginally, sublingually, buccally or rectally...
  17. doi The role of interventional radiology in obstetric hemorrhage
    M Gonsalves
    Radiology Department, St Georges Hospital, Tooting, London, UK
    Cardiovasc Intervent Radiol 33:887-95. 2010
    ..We review current literature regarding the role of interventional radiology in postpartum hemorrhage, abnormal placentation, abortion, and cervical ectopic pregnancy...
  18. ncbi Delayed postpartum hemorrhage due to cesarean scar dehiscence
    Tsuyoshi Baba
    Department of Obstetrics and Gynecology, Kitami Red Cross Hospital, Kitami, Japan
    Arch Gynecol Obstet 272:82-3. 2005
    A 28-year-old woman presented with massive postpartum hemorrhage. Laparotomy revealed a cesarean scar dehiscence due to wound infection.
  19. pmc Trends in postpartum hemorrhage in high resource countries: a review and recommendations from the International Postpartum Hemorrhage Collaborative Group
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK
    BMC Pregnancy Childbirth 9:55. 2009
    b>Postpartum hemorrhage (PPH) is a major cause of maternal mortality and morbidity worldwide. Several recent publications have noted an increasing trend in incidence over time...
  20. doi Hospitalized delivery and maternal deaths from obstetric hemorrhage in China from 1996 to 2006
    Xiaohong Li
    National Office for Maternal and Child Health Surveillance, West China Second University Hospital, Sichuan University, No 17 Section 3 Ren Min Nan Lu, Chengdu, Sichuan, China
    Acta Obstet Gynecol Scand 90:586-92. 2011
    ..To evaluate the role of hospitalized delivery in reducing maternal deaths from obstetric hemorrhage in urban and rural areas of China...
  21. doi Bedside assessment of fibrinogen level in postpartum haemorrhage by thrombelastometry
    C Huissoud
    Department of Obstetrics and Gynecology, Croix Rousse University Hospital, Hospices Civils de Lyon, Lyon, France
    BJOG 116:1097-102. 2009
    ..To establish whether reagent-supported thrombelastometry with the rotation thrombelastometry system (ROTEM) point-of-care device correlated with fibrinogen level in postpartum haemorrhages...
  22. doi Active management of the third stage of labour with and without controlled cord traction: a randomised, controlled, non-inferiority trial
    A Metin Gulmezoglu
    UNDP UNFPA WHO World Bank Special Programme of Research, Development and Research Training in Human Reproduction, World Health Organization, Geneva, Switzerland
    Lancet 379:1721-7. 2012
    ..We aimed to assess whether controlled cord traction can be omitted from active management of this stage without increasing the risk of severe haemorrhage...
  23. doi Predictive factors of advanced interventional procedures in a multicentre severe postpartum haemorrhage study
    Etienne Gayat
    Department of Anesthesiology and Critical Care Medicine, Mobile Care Unit, Lariboisiere University Hospital, AP HP, EA322, Paris Cedex 10, France
    Intensive Care Med 37:1816-25. 2011
    ..The aim of the study was to define factors predictive of the need for an AIP in the management of emergent PPH...
  24. doi Use of recombinant activated factor VII in severe post-partum haemorrhage: data from the Italian Registry: a multicentric observational retrospective study
    Giovanni Barillari
    Center for Hemorrhagic and Thrombotic Diseases, Department of Transfusion Medicine, General University Hospital of Udine, Italy
    Thromb Res 124:e41-7. 2009
    ..To report the Italian real experience in clinical practice about recombinant factor VII activated (rFVIIa) in Post-Partum Haemorrhage (PPH) treatment...
  25. doi Obstetric hemorrhage
    Patricia C Devine
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Semin Perinatol 33:76-81. 2009
    ..Depending on the definition that is used, postpartum hemorrhage complicates up to 18% of all deliveries...
  26. ncbi Obstetric critical care: a blueprint for improved outcomes
    Gerda G Zeeman
    Department of Obstetrics and Gynecology, University Medical Center, Groningen, The Netherlands
    Crit Care Med 34:S208-14. 2006
    ..This may be related to the pregnancy itself, aggravation of a preexisting illness, or complications of the (operative) delivery...
  27. ncbi Prevention of postpartum hemorrhage with misoprostol
    Z Alfirevic
    School of Reproductive and Developmental Medicine, University of Liverpool, Liverpool, UK
    Int J Gynaecol Obstet 99:S198-201. 2007
    ..a stable, orally active and cheap uterotonic, misoprostol would appear ideally suited to the prevention of postpartum hemorrhage (PPH) in the developing world...
  28. doi Standard haemostatic tests following major obstetric haemorrhage
    L de Lloyd
    Department of Anaesthesia, University Hospital of Wales and School of Medicine, Cardiff University, Cardiff, UK
    Int J Obstet Anesth 20:135-41. 2011
    ..Postpartum haemorrhage is an important cause of maternal morbidity and mortality. It is associated with haemostatic impairment which may exacerbate bleeding...
  29. ncbi Maternal and perinatal outcome in varying degrees of anemia
    Monika Malhotra
    Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India
    Int J Gynaecol Obstet 79:93-100. 2002
    ..To analyze the maternal and perinatal outcome in varying degrees of anemia...
  30. doi Blood component therapy in postpartum hemorrhage
    Andra H James
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA
    Transfusion 49:2430-3. 2009
    The purpose of this study was to examine blood component therapy in the treatment of postpartum hemorrhage.
  31. doi The use of fibrinogen concentrate to correct hypofibrinogenaemia rapidly during obstetric haemorrhage
    S F Bell
    Department of Anaesthesia, University Hospital of Wales, Cardiff, UK
    Int J Obstet Anesth 19:218-23. 2010
    ..These cases suggest that fibrinogen concentrate may be an effective addition to conventional treatments for obstetric haemorrhage associated with hypofibrinogenaemia...
  32. ncbi Risk factors and obstetric complications associated with macrosomia
    N E Stotland
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA
    Int J Gynaecol Obstet 87:220-6. 2004
    ..Macrosomia is associated with adverse maternal outcomes. The objective of this study was to characterize the epidemiology of macrosomia and related maternal complications...
  33. doi Policies for manual removal of placenta at vaginal delivery: variations in timing within Europe
    C Deneux-Tharaux
    INSERM, UMR S149, IFR 69, UPMC, Epidemiological Research Unit on Perinatal Health and Women s health, Hopital Tenon, Paris, France
    BJOG 116:119-24. 2009
    ..A randomised controlled trial is needed to provide definitive evidence on the risks and benefits of manual removal of placenta at different timings after vaginal delivery...
  34. pmc No reduction in instrumental vaginal births and no increased risk for adverse perineal outcome in nulliparous women giving birth on a birth seat: results of a Swedish randomized controlled trial
    Li Thies-Lagergren
    Department of Women s and Children s Health, Division of Reproductive and Perinatal Health Care, Karolinska Institutet, Stockholm SE 171 76, Sweden
    BMC Pregnancy Childbirth 11:22. 2011
    ....
  35. doi Critical care and transfusion management in maternal deaths from postpartum haemorrhage
    Marie Pierre Bonnet
    INSERM, UMR S953, Epidemiological Research Unit on Perinatal Health and Women s and Children s Health, Hopital Tenon, Paris, France
    Eur J Obstet Gynecol Reprod Biol 158:183-8. 2011
    ..The aim of this study was to describe critical care management, particularly transfusion practices, in cases of maternal deaths from PPH...
  36. pmc Administration of misoprostol by trained traditional birth attendants to prevent postpartum haemorrhage in homebirths in Pakistan: a randomised placebo-controlled trial
    N Mobeen
    Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan Gynuity Health Projects, New York, NY, USA
    BJOG 118:353-61. 2011
    ..to determine if misoprostol is safe and efficacious in preventing postpartum haemorrhage (PPH) when administered by trained traditional birth attendants (TBA) at home deliveries...
  37. pmc Risk factors for postpartum hemorrhage in vaginal deliveries in a Latin-American population
    Claudio G Sosa
    Perinatal Research Unit, School of Medicine, University of Uruguay, Montevideo, Uruguay
    Obstet Gynecol 113:1313-9. 2009
    To identify risk factors for immediate postpartum hemorrhage after vaginal delivery in a South American population.
  38. doi Surgical intervention in the management of postpartum hemorrhage
    Monjri Shah
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Semin Perinatol 33:109-15. 2009
    ..The type of hysterectomy (subtotal vs. total) must be individualized to each patient. Hemostatic agents may be particularly useful in patients who have excessive blood loss from raw tissue surfaces...
  39. doi Transfusion therapy in postpartum hemorrhage
    Anand Padmanabhan
    The Section of Transfusion Medicine and Cell Therapy, Department of Pathology and Cell Biology, Columbia University Medical Center, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    Semin Perinatol 33:124-7. 2009
    b>Postpartum hemorrhage (PPH) is an obstetric emergency that can occur following vaginal or cesarean delivery. Rapid diagnosis of PPH using laboratory and clinical parameters is an important first step in its management...
  40. doi Incidence and management of postpartum haemorrhage following the dissemination of guidelines in a network of 16 maternity units in France
    C Dupont
    Healthcare Practices Assessment Unit, Pole IMER des Hospices Civils de Lyon, 162, avenue Lacassagne, 69424 Lyon Cedex 03, France
    Int J Obstet Anesth 18:320-7. 2009
    ..In France obstetric haemorrhage is the leading cause of maternal death. The aim of this study was to evaluate if the management of postpartum haemorrhage at individual maternity units followed guidelines established by the Aurore Network...
  41. ncbi Postpartum hemorrhage
    Gowri Ramanathan
    Department of Obstetrics and Gynaecology, St George s Hospital Medical School, London UK
    J Obstet Gynaecol Can 28:967-73. 2006
    b>Postpartum hemorrhage (PPH) is the most important single cause of maternal death in both developing and developed countries. It arises from abnormalities in one of four basic processes, with uterine atony being the most common...
  42. ncbi Secondary postpartum hemorrhage: treatment with selective arterial embolization
    J P Pelage
    Department of Vascular Imaging, Hopital Lariboisiere, Paris, France
    Radiology 212:385-9. 1999
    To evaluate the efficacy and safety of selective arterial embolization of the uterine arteries in the management of intractable delayed postpartum hemorrhage.
  43. ncbi Estimation of blood loss after cesarean section and vaginal delivery has low validity with a tendency to exaggeration
    Christina Larsson
    Division of Obstetrics and Gynecology, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 85:1448-52. 2006
    ..Excessive bleeding is one of the major threats to women at childbirth. The aim of this study was to validate estimation of blood loss during delivery...
  44. ncbi Severe acute maternal morbidity and maternal death audit--a rapid diagnostic tool for evaluating maternal care
    L Cochet
    Medical Research Council Maternal and Infant Health Care Strategies Research Unit, Department of Obstetrics and Gynaecology, University of Pretoria
    S Afr Med J 93:700-2. 2003
    ..To analyse severe acute maternal morbidity (SAMM) and maternal mortality in the Pretoria region over a 2-year period (2000-2001)...
  45. pmc The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial
    Haleema Shakur
    Clinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trials 11:40. 2010
    ..At present there is little reliable evidence from randomised trials on the effectiveness of tranexamic acid in the treatment of postpartum haemorrhage...
  46. doi Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women receiving prophylactic oxytocin: a double-blind, randomised, non-inferiority trial
    Jennifer Blum
    Gynuity Health Projects, New York, NY 10010, USA
    Lancet 375:217-23. 2010
    ..This trial established whether sublingual misoprostol is non-inferior to intravenous oxytocin for treatment of post-partum haemorrhage in women receiving prophylactic oxytocin...
  47. ncbi Maternal morbidity associated with cesarean delivery without labor compared with spontaneous onset of labor at term
    V M Allen
    Department of Obstetrics and Gynecology, Dalhousie University, Halifax, Nova Scotia, Canada
    Obstet Gynecol 102:477-82. 2003
    ..To estimate the maternal morbidity associated with cesarean deliveries performed at term without labor compared with morbidity associated with spontaneous labor...
  48. doi Epidemiology of postpartum haemorrhage: a systematic review
    Guillermo Carroli
    Centro Rosarino de Estudios Perinatales CREP, Rosario, Argentina
    Best Pract Res Clin Obstet Gynaecol 22:999-1012. 2008
    ..For a reliable picture of PPH worldwide - its magnitude, distribution and consequences - a global survey tackling this condition is necessary...
  49. ncbi Incidence of severe pre-eclampsia, postpartum haemorrhage and sepsis as a surrogate marker for severe maternal morbidity in a European population-based study: the MOMS-B survey
    Wei Hong Zhang
    Unité de recherche en Santé Reproductive et Epidémiologie Périnatale, Département des Politiques et Systémes de Santé, Ecole de Santé Publique, Universite Libre de Bruxelles, Brussels, Belgium
    BJOG 112:89-96. 2005
    ..To describe the incidence of three conditions of acute severe maternal morbidity in selected regions in nine European countries...
  50. doi Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women not exposed to oxytocin during labour: a double-blind, randomised, non-inferiority trial
    Beverly Winikoff
    Gynuity Health Projects, New York, NY, USA
    Lancet 375:210-6. 2010
    ..This trial established whether sublingual misoprostol was similarly efficacious to intravenous oxytocin for treatment of post-partum haemorrhage in women not exposed to oxytocin during labour...
  51. ncbi Postpartum haemorrhage in nulliparous women: incidence and risk factors in low and high risk women. A Dutch population-based cohort study on standard (> or = 500 ml) and severe (> or = 1000 ml) postpartum haemorrhage
    Joke M J Bais
    Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Obstet Gynecol Reprod Biol 115:166-72. 2004
    ..To determine the incidence and risk factors for standard and severe postpartum haemorrhage (PPH) in vaginally delivering nulliparous women, before and after risk stratification...
  52. ncbi Blood transfusion for primary postpartum hemorrhage: a tertiary care hospital review
    Mrinalini Balki
    Department of Anesthesia and Pain Management, Mount Sinai Hospital, University of Toronto, Toronto ON
    J Obstet Gynaecol Can 30:1002-7. 2008
    ..To describe the common characteristics, clinical management, and outcome of patients requiring blood transfusion within 24 hours of delivery...
  53. pmc Association between anaemia during pregnancy and blood loss at and after delivery among women with vaginal births in Pemba Island, Zanzibar, Tanzania
    Justine A Kavle
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Health Popul Nutr 26:232-40. 2008
    ....
  54. ncbi Risk factors for hospital admission related to excessive and/or prolonged postpartum vaginal blood loss after the first 24 h following childbirth
    Sally Marchant
    Institute of Health and Community Studies, Bournemouth University, Bournemouth, Dorset, UK
    Paediatr Perinat Epidemiol 20:392-402. 2006
    ..It is considered that raising awareness about these factors, both among healthcare professionals and women themselves, may play an important part in the recognition and treatment of postpartum morbidity...
  55. ncbi Pharmacokinetics and adverse-effect profile of rectally administered misoprostol in the third stage of labor
    Rehan Uddin Khan
    Division of Maternal and Fetal Medicine, Imperial College School of Medicine, London, United Kingdom
    Obstet Gynecol 101:968-74. 2003
    ..To characterize the pharmacokinetics and adverse-effect profile of rectally administered misoprostol...
  56. pmc What measured blood loss tells us about postpartum bleeding: a systematic review
    N L Sloan
    Gynuity Health Projects, New York, NY, USA
    BJOG 117:788-800. 2010
    ..Meta-analyses of postpartum blood loss and the effect of uterotonics are biased by visually estimated blood loss...
  57. pmc Factors associated with peripartum hysterectomy
    Clara Bodelon
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Obstet Gynecol 114:115-23. 2009
    ..To identify factors associated with peripartum hysterectomy performed within 30 days postpartum...
  58. doi Strategies to manage major obstetric haemorrhage
    Arlene Wise
    South East of Scotland School of Anaesthesia, Edinburgh, UK
    Curr Opin Anaesthesiol 21:281-7. 2008
    ..Haemorrhage remains a cause of significant maternal morbidity and mortality. This review summarizes the prevention, management and treatment of obstetric haemorrhage and highlights recent advances and developments...
  59. doi Major obstetric hemorrhage
    Frederic J Mercier
    Department of Anesthesia and Intensive Care, Hopital Antoine Beclere, APHP and Universite Paris Sud, Clamart Cedex BP 405, France
    Anesthesiol Clin 26:53-66, vi. 2008
    ..Basic treatment of postpartum hemorrhage relies on manual removal of the placenta or manual exploration of the uterus plus bladder emptying and ..
  60. ncbi Postpartum hemorrhage after cesarean delivery: an analysis of risk factors
    Everett F Magann
    School of Women and Infants Health, King Edward Memorial Hospital, Perth, Australia
    South Med J 98:681-5. 2005
    To determine the incidence and risk factors for postpartum hemorrhage (PPH) associated with cesarean delivery.
  61. doi The risk of postpartum hemorrhage with selective serotonin reuptake inhibitors and other antidepressants
    Erin Salkeld
    Department of Public Health Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada
    J Clin Psychopharmacol 28:230-4. 2008
    ..is common and is often treated with antidepressants, we sought to determine if exposure to SSRI antidepressants in late pregnancy is associated with an increased risk of postpartum hemorrhage compared with non-SSRI antidepressants.
  62. doi Evaluation of multi-professional obstetric skills training for postpartum hemorrhage
    Veronika Markova
    Copenhagen University, Faculty of Health Sciences, Denmark
    Acta Obstet Gynecol Scand 91:346-52. 2012
    To evaluate the effect of multi-professional obstetric skills training on the incidence of postpartum hemorrhage (PPH) indicated by red blood cell (RBC) transfusion and time delay in surgical interventions before, during, and after ..
  63. doi Clinical evaluation during postpartum hemorrhage
    Joanne N Quinones
    Division of Maternal Fetal Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania, USA
    Clin Obstet Gynecol 53:157-64. 2010
    ..evaluations of the patient's status, it is helpful to have an evaluation strategy prepared for when a postpartum hemorrhage is encountered to facilitate interventions...
  64. doi Placenta accreta and postpartum hemorrhage
    Andrew D Hull
    Department of Reproductive Medicine, Division of Perinatal Medicine, University of California San Diego, CA 92103 8433, USA
    Clin Obstet Gynecol 53:228-36. 2010
    ..the failure of the placenta to separate normally from the uterus after delivery is accompanied by severe postpartum hemorrhage. The best outcomes in placenta accreta are in prenatally diagnosed electively delivered cases...
  65. pmc High fever following postpartum administration of sublingual misoprostol
    J Durocher
    Gynuity Health Projects, New York, NY, USA
    BJOG 117:845-52. 2010
    ..To explore what triggers an elevated body temperature of > or =40.0 degrees C in some women given misoprostol, a prostaglandin E1 analogue, for postpartum haemorrhage (PPH)...
  66. ncbi Investigation of an increase in postpartum haemorrhage in Canada
    K S Joseph
    Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, Canada
    BJOG 114:751-9. 2007
    ..To investigate the cause of a recent increase in hysterectomies for postpartum haemorrhage in Canada...
  67. doi Comparison of sublingual misoprostol, intravenous oxytocin, and intravenous methylergometrine in active management of the third stage of labor
    Gunjan Singh
    Department of Obstetrics and Gynecology, University College of Medical Sciences, Guru Teg Bahadur Hospital, New Delhi, India
    Int J Gynaecol Obstet 107:130-4. 2009
    ..To compare the efficacy and adverse effects of sublingual misoprostol, intravenous oxytocin, and intravenous methylergometrine in active management of the third stage of labor (AMTSL)...
  68. doi Surgical treatment of intractable postpartum hemorrhage and changing trends in modern obstetric perspective
    Tayfun Gungor
    Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Women Health, Education and Research Hospital, Saime Kadin Mahallesi, Calikavak Sokak, No 22 4 Abidinpasa Mamak, Ankara, Turkey
    Arch Gynecol Obstet 280:351-5. 2009
    To update the prevalence and risk factors of intractable postpartum hemorrhage (IPH) and evaluate the effectiveness of surgical treatment modalities.
  69. doi Using Uniject to increase the use of prophylactic oxytocin for management of the third stage of labor in Latin America
    Fernando Althabe
    Institute for Clinical Effectiveness and Health Policy, IECS, Buenos Aires, Argentina
    Int J Gynaecol Obstet 114:184-9. 2011
    ..To evaluate a multifaceted intervention for effectiveness in increasing the use of prophylactic oxytocin by birth attendants (obstetricians, midwives, and nurses) working in small maternity hospitals in Argentina...
  70. ncbi Oxytocin in prefilled Uniject injection devices for managing third-stage labor in Indonesia
    V D Tsu
    Program for Appropriate Technology in Health PATH, Seattle, WA 98107, USA
    Int J Gynaecol Obstet 83:103-11. 2003
    ..b>Postpartum hemorrhage rates did not change substantially...
  71. ncbi Analysis of the venous thromboembolic risk associated with severe postpartum haemorrhage in the NOHA First cohort
    Celine Chauleur
    Laboratoire d Hematologie, Centre Hospitalier Universitaire, Groupe Hospitalo Universitaire Caremeau, place du Pr Robert Debré, F 30029 Nimes cedex 9, France
    Thromb Haemost 100:773-9. 2008
    ..Severe PPH increases the risk of postpartum SVT, but transfusion with platelet units and plasma supplementation using fresh frozen plasma or fibrinogen concentrates do not markedly modulate the risk of venous thrombosis...
  72. ncbi The use of recombinant factor VIIa in severe postpartum hemorrhage
    Shmuel Segal
    Barzilai Medical Center, Ashkelon, Israel
    Acta Obstet Gynecol Scand 83:771-2. 2004
  73. ncbi Medical and conservative surgical management of postpartum hemorrhage
    George Stanley Condous
    Division of Obstetrics and Gynaecology, St George s Hospital Medical School, London, England
    J Obstet Gynaecol Can 25:931-6. 2003
    Massive postpartum hemorrhage (PPH) is a major cause of maternal mortality in the United Kingdom and worldwide. Life-threatening PPH occurs with a frequency of 1 in 1000 deliveries in the developed world...
  74. ncbi Obstetric skills drills: evaluation of teaching methods
    L Birch
    Practice Development and Research Unit, Duchess of Westminster Wing, Arrowe Park Hospital, Upton, Wirral, Cheshire CH49 5PE, United Kingdom
    Nurse Educ Today 27:915-22. 2007
    ..To determine the most effective method of delivering training to staff on the management of an obstetric emergency...
  75. ncbi [Clinical study on prevention of postpartum hemorrhage of cesarean section using hemabat in high risk pregnant women]
    Lian Fang Wu
    Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
    Zhonghua Fu Chan Ke Za Zhi 42:577-81. 2007
    To observe the effect and safety of hemabat (H) on prevention of postpartum hemorrhage in cesarean section and after cesarean section in high risk pregnant women.
  76. ncbi How we treat: management of life-threatening primary postpartum hemorrhage with a standardized massive transfusion protocol
    Matthew Burtelow
    Department of Pathology, Stanford University Medical Center, Stanford, California, USA
    Transfusion 47:1564-72. 2007
    Management of massive, life-threatening primary postpartum hemorrhage in the labor and delivery service is a challenge for the clinical team and hospital transfusion service...
  77. doi A randomised controlled trial of oxytocin 5IU and placebo infusion versus oxytocin 5IU and 30IU infusion for the control of blood loss at elective caesarean section--pilot study. ISRCTN 40302163
    Deirdre J Murphy
    Academic Department of Obstetrics and Gynaecology, Coombe Women s Hospital and Trinity College, University of Dublin, Dublin 8, Ireland
    Eur J Obstet Gynecol Reprod Biol 142:30-3. 2009
    ..To compare the blood loss at elective lower segment caesarean section with administration of oxytocin 5IU bolus versus oxytocin 5IU bolus and oxytocin 30IU infusion and to establish whether a large multi-centre trial is feasible...
  78. ncbi Successful use of recombinant factor VIIa for treatment of severe postpartum hemorrhage
    Ankie E W Hamaekers
    Department of Anaesthesiology, University Hospital Maastricht, Maastricht, The Netherlands
    Am J Crit Care 15:399-401. 2006
  79. doi Variation in the postpartum hemorrhage rate in a clinical trial of oral misoprostol
    Shivaprasad S Goudar
    Jawaharlal Nehru Medical College, Belgaum, Karnataka, India
    J Matern Fetal Neonatal Med 21:559-64. 2008
    The main objective of this study was to identify factors associated with variation in the rate of acute postpartum hemorrhage (PPH), defined as blood loss >or= 500 mL within 2 hours of delivery, observed in a randomized clinical trial ..
  80. ncbi Misoprostol and active management of the third stage of labor
    N Prata
    Bixby Program in Population, Family Planning and Maternal Health, School of Public Health, University of California, Berkeley, USA
    Int J Gynaecol Obstet 94:149-55. 2006
    ..To compare current practices for the active management of the third stage of labor (AMTSL) with the use of 600 mug of oral misoprostol...
  81. doi Risk factors and interventions associated with major primary postpartum hemorrhage unresponsive to first-line conventional therapy
    Hatem A Mousa
    Division of Perinatal and Reproductive Medicine, University of Liverpool, Liverpool, UK
    Acta Obstet Gynecol Scand 87:652-61. 2008
    To examine risk factors and interventions associated with major primary postpartum hemorrhage (PPH) unresponsive to first-line conventional therapy.
  82. ncbi Improving the accuracy of estimated blood loss at obstetric haemorrhage using clinical reconstructions
    P Bose
    Department of Obstetrics and Gynaecology, Queen Charlotte s Hospital, London, UK Email
    BJOG 113:919-24. 2006
    ....
  83. pmc Factors associated with acute postpartum hemorrhage in low-risk women delivering in rural India
    Stacie E Geller
    University of Illinois, Chicago College of Medicine, Chicago, IL, USA
    Int J Gynaecol Obstet 101:94-9. 2008
    b>Postpartum hemorrhage (PPH), a major cause of maternal mortality and morbidity in low-income countries, can occur unpredictably...
  84. ncbi Risk factors for primary postpartum hemorrhage in Bhumibol Adulyadej Hospital
    Wibool Rueangchainikhom
    Department of Obstetrics and Gynecology, Bhumibol Adulyadej Hospital, Bangkok, Thailand
    J Med Assoc Thai 92:1586-90. 2009
    b>Postpartum hemorrhage remains one of the main causes of maternal morbidity and mortality in both developed and developing countries...
  85. doi Secondary postpartum hemorrhage due to a pseudoaneurysm rupture at the fundal area of the uterus: a case treated with selective uterine arterial embolization
    Sang Wook Yi
    Department of Obstetrics and Gynecology, Gangneung Asan Hospital, College of Medicine, University of Ulsan, Gangneung, South Korea
    Fertil Steril 93:2048-9. 2010
    A 37-year-old woman with secondary postpartum hemorrhage due to a pseudoaneurysm rupture of the uterus was given selective uterine arterial embolization, and she was discharged in stable condition on the fourth postembolization day...
  86. ncbi Laparoscopic bipolar coagulation of uterine vessels to manage delayed postpartum hemorrhage
    Yu Ching Chou
    Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, 201, Section 2, Shih Pai Road, Taipei 112, Taiwan
    J Am Assoc Gynecol Laparosc 9:541-4. 2002
    b>Postpartum hemorrhage (PPH) is a big challenge for obstetricians. Fertility-preserving procedures are encouraged, especially in young women...
  87. doi Carbetocin versus oxytocin for the prevention of postpartum haemorrhage following caesarean section: the results of a double-blind randomised trial
    G Attilakos
    Directorate of Women s and Children s Health, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
    BJOG 117:929-36. 2010
    ..To compare the effectiveness of carbetocin and oxytocin when they are administered after caesarean section for prevention of postpartum haemorrhage (PPH)...
  88. ncbi Active versus expectant management of the third stage of labor in rural Ghana
    Diederike Geelhoed
    Holy Family Hospital, Berekum, Ghana
    Acta Obstet Gynecol Scand 81:172-3. 2002
  89. doi Risks for peroperative excessive blood loss in cesarean delivery
    Toril Kolås
    Department of Obstetrics and Gynecology, Innlandet Hospital Trust, Lillehammer, Norway
    Acta Obstet Gynecol Scand 89:658-63. 2010
    ..To analyze risk factors for peroperative excessive blood loss at cesarean delivery...
  90. doi [Postpartum hemorrhage--an update]
    Wiebke Gogarten
    Klinik für Anästhesiologie und operative Intensivmedizin am Klinikum Harlaching in München
    Anasthesiol Intensivmed Notfallmed Schmerzther 46:508-14. 2011
    b>Postpartum hemorrhage remains a major cause of maternal morbidity and mortality...
  91. doi Challenges in managing postpartum hemorrhage in resource-poor countries
    Mahantesh Karoshi
    Department of Obstetrics and Gynecology, Kingston Hospital, Galsworthy Road, Kingston upon Thames, Surrey, United Kingdom
    Clin Obstet Gynecol 52:285-98. 2009
    Managing postpartum hemorrhage depends in part on having a prepared mind, a complement of trained coworkers, and full access to modern therapies...
  92. doi Prolonged second stage of labor and postpartum hemorrhage
    Michael C Lu
    Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1772, USA
    J Matern Fetal Neonatal Med 22:227-32. 2009
    To examine the relationship between prolonged second stage and postpartum hemorrhage (PPH).
  93. doi Use of additional oxytocin to reduce blood loss at elective caesarean section: A randomised control trial
    Kemal Gungorduk
    Erzincan Military Hospital, Turkey
    Aust N Z J Obstet Gynaecol 50:36-9. 2010
    ....
  94. doi Five unit bolus oxytocin at cesarean delivery in women at risk of atony: a randomized, double-blind, controlled trial
    Kylie J King
    Department of Anaesthesia, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, New South Wales 2310, Australia
    Anesth Analg 111:1460-6. 2010
    I.v. bolus oxytocin is used routinely during cesarean delivery to prevent postpartum hemorrhage. Its adverse hemodynamic effects are well known, resulting in a recent change in dose from 10 IU to 5...
  95. ncbi Prevention of postpartum hemorrhage: options for home births in rural Ethiopia
    N Prata
    Bixby Center for Population, Health and Sustainability, University of California, Berkeley, School o Public Health, 229 University Hall, Berkeley, CA 94720, USA
    Afr J Reprod Health 13:87-95. 2009
    This paper sought to determine the safety and feasibility of home-based prophylaxis of postpartum hemorrhage (PPH) with misoprostol, including assessment of the need for referrals and additional interventions...
  96. ncbi Oral misoprostol for prevention of postpartum hemorrhage by paramedical workers in India
    N Chandhiok
    Division of Reproductive Health and Nutrition, Indian Council of Medical Research, Ansari Nagar, New Delhi
    Int J Gynaecol Obstet 92:170-5. 2006
    To study whether paramedical workers from rural primary health centers in India are able to administer oral misoprostol and actively manage the third stage of labor to prevent postpartum hemorrhage (PPH).
  97. ncbi Oral misoprostol for third stage of labor: a randomized placebo-controlled trial
    D V Surbek
    Department of Obstetrics and Gynecology, University of Basel, Switzerland
    Obstet Gynecol 94:255-8. 1999
    ..To investigate whether orally administered misoprostol during the third stage of labor is efficient in reducing postpartum blood loss...
  98. ncbi Hypogastric arterial selective and superselective embolization for severe postpartum hemorrhage: a retrospective review of 36 cases
    C Boulleret
    Service de Gynecologie Obstetrique, Clermont Ferrand University Hospital, BP69 63003, France
    Cardiovasc Intervent Radiol 27:344-8. 2004
    We report on embolization in 36 cases of postpartum hemorrhage (PPH)...
  99. ncbi Treatment of postpartum hemorrhage with misoprostol
    J Blum
    Gynuity Health Projects, New York, NY 10010, USA
    Int J Gynaecol Obstet 99:S202-5. 2007
    A literature review was conducted to determine whether misoprostol is an effective treatment for postpartum hemorrhage (PPH) and in what dose...
  100. ncbi Massive primary postpartum haemorrhage: setting up standards of care
    Lumaan Sheikh
    Department of Obstetrics and Gynaecology, The Aga Khan University, Karachi
    J Pak Med Assoc 56:26-31. 2006
    ..To review practice of massive primary postpartum haemorrhage management and develop a protocol...
  101. ncbi Intrauterine balloon tamponade in the management of postpartum hemorrhage
    Victor Dabelea
    Department of Obstetrics and Gynecology, Exempla Saint Joseph Hospital, Denver, Colorado 80205, USA
    Am J Perinatol 24:359-64. 2007
    ..our experience with the use of intrauterine tamponade with balloon catheters in the management of severe postpartum hemorrhage. This is a case series report of 23 patients with postpartum hemorrhage unresponsive to medical therapy ..

Research Grants43

  1. UIC-JNMC Women's & Children's Research Unit
    Richard Derman; Fiscal Year: 2006
    ..Out initial collaborative effort will be to conduct a prospective study directed at the problem of postpartum hemorrhage. Our study will be carried out in the Belgaum District (State of Karnataka) and test the hypothesis that ..
  2. Non-pneumatic Anti-Shock Garment for Obstetrical Hemorrhage
    Suellen Miller; Fiscal Year: 2009
    ....
  3. Non-pneumatic Anti-Shock Garment for Obstetrical Hemorrhage
    Suellen Miller; Fiscal Year: 2007
    ..abstract_text> ..
  4. Non-pneumatic Anti-Shock Garment for Obstetrical Hemorrhage
    Suellen Miller; Fiscal Year: 2010
    ....
  5. UIC Program for Interdisciplinary Careers in Women's Health Research
    Stacie Geller; Fiscal Year: 2007
    ..Work in women's health ranges from the molecular and cellular level to the community level; these levels are inter-related. Therefore, UlC's research programs are translational and incorporate multiple levels of analysis. ..
  6. Risk factors for medically indicated preterm birth in a Latin American population
    CLAUDIO GERARDO SOSA; Fiscal Year: 2010
    ..The long-term goal of this research program is to develop intervention strategies that are based on the risk factors identified in the proposed study resulting in decreased morbidity and mortality. ..
  7. Risk factors for medically indicated preterm birth in a Latin American population
    Claudio Sosa; Fiscal Year: 2007
    ..The long-term goal of this research program is to develop intervention strategies that are based on the risk factors identified in the proposed study resulting in decreased morbidity and mortality. ..
  8. Genomic/Proteomic Premature Birth Research Clinical Core
    RADOSLAW BUKOWSKI; Fiscal Year: 2007
    ..Our concept protocols propose to examine networks of co-expressed genes in the uterus during preterm birth. We accept the RFA's capitation and participatory stipulations and stand ready to contribute as a member of the Network. ..
  9. MIDCAREER AWARD IN PATIENT ORIENTED OBSTETRIC RESEARCH
    Dwight Rouse; Fiscal Year: 2004
    ..Finally, the effectiveness of an intervention (how it would perform under conditions of actual clinical practice) is an attribute that, in many situations, is as important as its efficacy (how it performs under ideal conditions). ..
  10. GENETIC TESTING AND THE ECONOMICS OF LIFE INSURANCE
    David Asch; Fiscal Year: 2002
    ..abstract_text> ..
  11. CHLORHEXIDINE IRRIGATION TO PREVENT INFECTION
    Dwight Rouse; Fiscal Year: 2001
    ....
  12. Age, Disruption, and Life Reorganization after Hurricane Katrina
    Vincanne Adams; Fiscal Year: 2010
    ..Examining the process of unwanted change in later life can provide many insights about how people deal with change, the ways they adjust and accommodate it in daily life, and the effects of unwanted change on health and well-being. ..
  13. Blood Donation and HIV Prevention in China
    Vincanne Adams; Fiscal Year: 2006
    ..Data collection will occur in Shanghai; overall project oversight and data analysis will occur in San Francisco, CA. ..
  14. NICHD Maternal Fetal Medicine Units Network
    Dwight Rouse; Fiscal Year: 2007
    ..We believe that we remain well positioned for competitive renewal as an NICHD MFMU Network center for the next five years. ..
  15. Age, Disruption, and Life Reorganization after Hurricane Katrina
    Vincanne Adams; Fiscal Year: 2007
    ..Examining the process of unwanted change in later life can provide many insights about how people deal with change, the ways they adjust and accommodate it in daily life, and the effects of unwanted change on health and well-being. ..
  16. Antenatal and preschool iron and zinc use and cognition
    Parul Christian; Fiscal Year: 2007
    ..The study will fill critical gaps in knowledge and inform policy on the efficacy of selective micronutrient interventions in pregnancy and early childhood to improve school-aged cognition. ..
  17. The Effects of HIV/AIDS Stigma on Use of Services by Pregnant Women in Kenya
    Janet Turan; Fiscal Year: 2007
    ....