Research Topics
Genomes and Genes
| fetal deathSummarySummary: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH. Top Publications
Research Grants
| Scientific Experts
|
Detail Information
Publications
Effect of maternal multiple micronutrient supplementation on fetal loss and infant death in Indonesia: a double-blind cluster-randomised trialA H Shankar
Helen Keller International, Jakarta, Indonesia Johns Hopkins University, Baltimore, MD, USA
Lancet 371:215-27. 2008..We assessed the effect of maternal supplementation with MMN, compared with IFA, on fetal loss and infant death in the setting of routine prenatal care services...
Reducing stillbirths: screening and monitoring during pregnancy and labourRachel A Haws
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
BMC Pregnancy Childbirth 9:S5. 2009..2 million estimated annual stillbirths, as well as minimise maternal and neonatal morbidity and mortality...
Prepregnancy obesity and fetal death: a study within the Danish National Birth CohortEllen Aagaard Nohr
Danish Epidemiology Science Centre, Institute of Public Health, University of Aarhus, Aarhus, Denmark
Obstet Gynecol 106:250-9. 2005To examine the association between high prepregnancy body mass index and fetal death, allowing for the effects of gestational age, weight gain, and maternal diseases in pregnancy.
Epigenetic instability in ES cells and cloned miceD Humpherys
Whitehead Institute for Biomedical Research, Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge MA 02142, USA
Science 293:95-7. 2001..These data imply that even apparently normal cloned animals may have subtle abnormalities in gene expression...
Global report on preterm birth and stillbirth (3 of 7): evidence for effectiveness of interventionsFernando C Barros
Post Graduate Course in Health and Behaviour, Universidade Catolica de Pelotas, Brazil
BMC Pregnancy Childbirth 10:S3. 2010..Survival of preterm newborns may also be improved with interventions given during these times or soon after birth. This comprehensive review assesses existing interventions for low- and middle-income countries (LMICs)...
Managing Q fever during pregnancy: the benefits of long-term cotrimoxazole therapyXavier Carcopino
Service de Gynecologie Obstetrique, Hopital Nord, Chemin des Bourrely, France
Clin Infect Dis 45:548-55. 2007..During pregnancy, it may result in obstetric complications, such as spontaneous abortion, intrauterine growth retardation, intrauterine fetal death, and premature delivery. Pregnant women are exposed to the risk of chronic Q fever.
Etiology and prevention of stillbirthRuth C Fretts
Harvard Vanguard Medical Associates, Wellesley, MA 02481, USA
Am J Obstet Gynecol 193:1923-35. 2005..This is a systematic review of the literature on the causes of stillbirth and clinical opinion regarding strategies for its prevention...
Vitamins and perinatal outcomes among HIV-negative women in TanzaniaWafaie W Fawzi
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
N Engl J Med 356:1423-31. 2007..Prematurity and low birth weight are associated with high perinatal and infant mortality, especially in developing countries. Maternal micronutrient deficiencies may contribute to these adverse outcomes...
Reducing stillbirths: behavioural and nutritional interventions before and during pregnancyMohammad Yawar Yakoob
Division of Maternal and Child Health, The Aga Khan University, Karachi 74800, Pakistan
BMC Pregnancy Childbirth 9:S3. 2009..Interventions to reduce these risks could reduce the resulting burden of stillbirths, but the evidence for the impact of such interventions has not yet been comprehensively evaluated...
Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndromePatricia Redecha
Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York, USA
J Clin Invest 118:3453-61. 2008..receptor 2 (PAR2), and stimulation of this receptor led to neutrophil activation, trophoblast injury, and fetal death. An antibody specific for human TF that has little impact on coagulation, but potently inhibits TF/Factor VIIa (..
Stillbirth classification--developing an international consensus for research: executive summary of a National Institute of Child Health and Human Development workshopUma M Reddy
Pregnancy and Perinatology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7510, USA
Obstet Gynecol 114:901-14. 2009..In all cases, owing to lack of sufficient knowledge about disease states and normal development, there will be a degree of uncertainty regarding whether a specific condition was indeed the cause of death...
Second-trimester abortion for fetal anomalies or fetal death: labor induction compared with dilation and evacuationAmy G Bryant
Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Obstet Gynecol 117:788-92. 2011To compare the safety and effectiveness of dilation and evacuation (D&E) and labor-induction abortion performed for fetal anomalies or fetal death in the second trimester.
Perinatal mortality in developing countriesJelka Zupan
Department of Making Pregnancy Safer, World Health Organization, Geneva
N Engl J Med 352:2047-8. 2005
Obesity in pregnancy: pre-conceptional to postpartum consequencesKristina Arendas
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The Ottawa Hospital, University of Ottawa, Ottawa ON
J Obstet Gynaecol Can 30:477-88. 2008..To review the effects of obesity on reproduction and pregnancy outcome...
Fetal death in mice lacking 5alpha-reductase type 1 caused by estrogen excessM S Mahendroo
Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas 75235 9046, USA
Mol Endocrinol 11:917-27. 1997..Administration of an estrogen receptor antagonist or inhibitors of aromatase reverse the high rate of fetal death in the mutant mice, and estradiol treatment of wild type pregnant mice causes fetal wastage...
Analysis of stillbirths in a Nigerian mission hospitalAlphonsus N Onyiriuka
Department of Child Health University of Benin Teaching Hospital PMB 1111, Benin City, Nigeria
Nig Q J Hosp Med 19:27-31. 2009..Knowledge of the relative importance of the different causes of stillbirth is lacking, even in hospital settings...
Infection and stillbirthElizabeth M McClure
Department of Epidemiology, UNC Global School of Public Health, Chapel Hill, North Carolina, USA
Semin Fetal Neonatal Med 14:182-9. 2009..However, because infection-related stillbirth is uncommon in developed countries, and because those that do occur are caused by a wide variety of organisms, reducing this etiologic component of stillbirth much further will be difficult...
A kick from within--fetal movement counting and the cancelled progress in antenatal careJ Frederik Frøen
Department of Obstetrics and Gynecology, Rikshospitalet University Clinic, University of Oslo, Norway
J Perinat Med 32:13-24. 2004..While screening for fetal well-being by maternal fetal movement counting can reduce fetal mortality rates, a resurrection in research activity is urgently needed to optimize its benefits...
Delivering interventions to reduce the global burden of stillbirths: improving service supply and community demandZulfiqar A Bhutta
Division of Maternal and Child Health, The Aga Khan University, Karachi, Pakistan
BMC Pregnancy Childbirth 9:S7. 2009....
Waddlia chondrophila, a potential agent of human fetal deathDavid Baud
University of Lausanne, Lausanne, Switzerland
Emerg Infect Dis 13:1239-43. 2007..Waddlia seroprevalence was higher in women who had had sporadic and recurrent miscarriages than in control women (p < 0.001). Waddlia spp. may represent a cause of human fetal loss...
Risk of perinatal death associated with labor after previous cesarean delivery in uncomplicated term pregnanciesGordon C S Smith
Department of Obstetrics and Gynaecology, Cambridge University, Rosie Maternity Hospital, Cambridge, CB2 2QQ, England
JAMA 287:2684-90. 2002..However, no reliable data exist on the effect of a trial of labor on the risk of perinatal death in otherwise uncomplicated term pregnancies...
Reducing stillbirths: prevention and management of medical disorders and infections during pregnancyEsme V Menezes
Division of Maternal and Child Health, The Aga Khan University, Karachi 74800, Pakistan
BMC Pregnancy Childbirth 9:S4. 2009..Poorly recognised, untreated or inadequately treated maternal infections such as syphilis and malaria, and maternal conditions including hypertensive disorders, are known risk factors for stillbirth...
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa BA A Beg
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
Nature 376:167-70. 1995..These results indicate that RelA controls inducible, but not basal, transcription in NF-kappa B-regulated pathways...
Somatic cell nuclear transferI Wilmut
Roslin Institute, Roslin, Midlothian EH25 9PS, UK
Nature 419:583-6. 2002..When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term...
The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesisP Riley
Program in Development and Fetal Health, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
Nat Genet 18:271-5. 1998..Their heart tubes showed abnormal looping and ventricular myocardial differentiation. Therefore, Hand1 is essential for differentiation of both trophoblast and cardiomyocytes, which are embryologically distinct cell lineages...
Herpes simplex virus type-2 infection in pregnancy: no risk of fetal death: results from a nested case-control study within 35,940 womenAnne Eskild
Section of Epidemiology, National Institute of Public Health, Oslo, Norway
BJOG 109:1030-5. 2002OBJECTIVE: The aim of this study was to assess the association of fetal death with herpes simplex virus type-2 (HSV-2) antibody status during pregnancy: 1. presence of antibodies in first trimester; 2...
Birth weight and fetal death in the United States: the effect of maternal diabetes during pregnancyMyriam A J Mondestin
Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School/Saint Peter's University Hospital, New Brunswick, NJ, USA
Am J Obstet Gynecol 187:922-6. 2002OBJECTIVE: Our purpose was to evaluate the association between birth weight (BW) and fetal death (FD) among pregnant nondiabetic and diabetic patients...
Fever in pregnancy and risk of fetal death: a cohort studyAnne Marie Nybo Andersen
Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
Lancet 360:1552-6. 2002Hyperthermia acts as a teratogen in some animals where it can induce resorption of the fetus and fetal death. Fever during pregnancy, especially in the period of embryogenesis, is also suspected as being a risk factor for fetal death in ..
Diverse placental pathologies as the main causes of fetal deathFleurisca J Korteweg
Department of Obstetrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Obstet Gynecol 114:809-17. 2009To estimate the occurrence of placental causes of fetal death in relation to different gestational ages and their clinical manifestations during pregnancy.
Reduced body weight and increased postimplantation fetal death in tyrosylprotein sulfotransferase-1-deficient miceYing Bin Ouyang
Cardiovascular Biology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA
J Biol Chem 277:23781-7. 2002..Tpst1(-/-) males and females per se is normal, Tpst1(-/-) females have significantly smaller litters because of fetal death between 8.5 and 15.5 days postcoitum...
Fetal death as a result of placental immune reconstitution inflammatory syndromeF Caby
Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitie Salpetriere, Assistance Publique des Hopitaux de Paris AP HP, Paris, France
J Infect 61:185-8. 2010..A fetal death was diagnosed 7 weeks after starting HAART (CD4 = 185/mm(3), HIV-1 RNA = 391 copies/mL) with a positive ..
Atrial hemangioma: a rare cause of hydrops fetalis and intrauterine fetal deathChuan-Fei Hou
Eur J Obstet Gynecol Reprod Biol 130:271-2. 2007
Couple distress after sudden infant or perinatal death: a 30-month follow upJ C Vance
Department of Paediatrics and Child Health, University of Queensland, St Lucia, Queensland, Australia
J Paediatr Child Health 38:368-72. 2002..Gender differences are common and partners' needs may change over time. Early recognition of these differences may facilitate longer-term adjustment for both partners...
Maternal and fetal inflammatory responses in unexplained fetal deathS Blackwell
Department of Obstetrics and Gynecology, Wayne State University/Hutzel Hospital, Detroit, Michigan, 48201, USA
J Matern Fetal Neonatal Med 14:151-7. 2003OBJECTIVE: The role of intra-amniotic infection in the etiology of fetal death has been proposed...
Clinical value of postnatal autopsy and genetics consultation in fetal deathL A Hefler
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
Am J Med Genet 104:165-8. 2001..present study was to investigate the clinical use of postnatal autopsy and genetics consultation in cases of fetal death in a teaching hospital...
Maternal thyroid function at 11 to 13 weeks of gestation and subsequent fetal deathGhalia Ashoor
Harris Birthright Research Centre, King s College Hospital, London, United Kingdom
Thyroid 20:989-93. 2010..Our hypothesis is that maternal thyroid function in the first trimester is altered in pregnancies ending in miscarriage or fetal death.
How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic reviewZarko Alfirevic
Liverpool Women s Hospital, Crown Street, Liverpool L8 7SS, UK
Eur J Obstet Gynecol Reprod Biol 101:6-14. 2002..To determine whether inherited and acquired thrombophilias are associated with adverse obstetric complications...
Mortality associated with congenital syphilis in the United States, 1992-1998Deborah A Gust
Division of STD Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
Pediatrics 109:E79-9. 2002..To summarize national trends in the incidence of congenital syphilis (CS) and associated mortality...
Syphilis-associated perinatal and infant mortality in rural MalawiJ McDermott
Epidemiologist, Malaria Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333
Bull World Health Organ 71:773-80. 1993....
Maternal and congenital syphilis in Shanghai, China, 2002 to 2006Liping Zhu
Shanghai First Maternity and Infant Hospital Tongji University, Shanghai Women s Health Institute, Shanghai, China
Int J Infect Dis 14:e45-8. 2010..To assess the trends and determinants of maternal and congenital syphilis in Shanghai, China...
Intrauterine infection may be a major cause of stillbirth in SwedenE Tolockiene
Department of Pathology, University of Lund, Lund, Sweden
Acta Obstet Gynecol Scand 80:511-8. 2001..CONCLUSIONS: Thus, a large part of otherwise unexplained stillbirths might be due to ascending infections...
Detection of cytomegalovirus, parvovirus B19 and herpes simplex viruses in cases of intrauterine fetal death: association with pathological findingsGaryfallia Syridou
Department of Microbiology, Medical School, University of Athens, Athens, Greece
J Med Virol 80:1776-82. 2008..B19 (PB19) and herpes simplex virus types 1 and 2 (HSV-1/2) cause fetal infections, which may lead to fetal death. In a prospective case-control study we examined the incidence of these viruses in intrauterine fetal death and ..
Fetal morbidity and mortality after acute human parvovirus B19 infection in pregnancy: prospective evaluation of 1018 casesMartin Enders
Labor Enders und Partner, Institut fur Virologie, Infektiologie und Epidemiologie e V, Stuttgart, Germany
Prenat Diagn 24:513-8. 2004..To determine more precisely the incidence of fetal complications following maternal parvovirus B19 infection at various gestational ages...
Preventing those so-called stillbirthsJonathan M Spector
UMass Memorial Children's Medical Center, Worcester, MA, USA
Bull World Health Organ 86:315-6. 2008
Reducing stillbirths: interventions during labourGary L Darmstadt
Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
BMC Pregnancy Childbirth 9:S6. 2009..The evidence for impact of intrapartum interventions on stillbirth and perinatal mortality outcomes has not yet been systematically examined...
High prevalence of the prothrombin gene mutation in women with intrauterine growth retardation, abruptio placentae and second trimester lossM J Kupferminc
Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Israel
Acta Obstet Gynecol Scand 79:963-7. 2000..Our objective was to investigate the association between pregnancy complications and the guanine 20210 adenine (G20210A) mutation in prothrombin gene...
Management of other complications specific to monochorionic twin pregnanciesL Pasquini
Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, Du Cane Road, Hammaersmith, W12 0HS London, UK
Best Pract Res Clin Obstet Gynaecol 18:577-99. 2004..Recent strategies to reduce the high perinatal mortality due to cord entanglement in antenatally diagnosed monoamniotic twins including medical amnioreduction and elective caesarean delivery at 32 weeks, are also discussed...
Maternal risk factors associated with fetal death during antenatal care in low-resource tertiary hospitalsOlufemi T Oladapo
Maternal and Fetal Health Research Unit, Department of Obstetrics and Gynaecology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria
Aust N Z J Obstet Gynaecol 47:383-8. 2007Data on maternal characteristics that could predict antepartum fetal death in women receiving antenatal care in resource-constrained settings are limited...
Maternal age and risk of fetal death in singleton gestations: USA, 1995-2000J C Canterino
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School/Robert Wood Johnson University Hospital, New Brunswick, USA
J Matern Fetal Neonatal Med 15:193-7. 2004OBJECTIVE: To determine the magnitude of risk for fetal death among singleton pregnancies in relation to maternal age, and to compare the risks with other common indications for fetal testing...
Frequency of human parvovirus B19 infection in intrauterine fetal deathT Tolfvenstam
Departments of Clinical Virology, Karolinska Institutet, Huddinge University Hospital, SE 141 86, Stockholm, Sweden
Lancet 357:1494-7. 2001Parvovirus B19 is known to cause fetal death in the second trimester, mainly in combination with hydrops fetalis...
Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2Yong Tian
Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
J Biol Chem 281:28438-49. 2006..These results illustrate a non-redundant role for EtnK2 expression in regulating placental hemostasis...
Maternal and perinatal outcomes associated with a trial of labor after prior cesarean deliveryMark B Landon
Department of Obstetrics and Gynecology at Ohio State University, College of Medicine and Public Health, Columbus 43210 1228, USA
N Engl J Med 351:2581-9. 2004..The absolute and relative risks associated with a trial of labor in women with a history of cesarean delivery, as compared with elective repeated cesarean delivery without labor, are uncertain...
Bacterial vaginosis as a risk factor for preterm delivery: a meta-analysisHarald Leitich
Departments of Obstetrics and Gynecology and Medical Computer Sciences, University of Vienna, Vienna, Austria
Am J Obstet Gynecol 189:139-47. 2003..We performed a meta-analysis to evaluate bacterial vaginosis as a risk factor for preterm delivery...
Antiretroviral therapy during pregnancy and the risk of an adverse outcomeRuth E Tuomala
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston 02115, USA
N Engl J Med 346:1863-70. 2002..Some studies suggest that combination antiretroviral therapy in pregnant women with human immunodeficiency virus type 1 (HIV-1) infection increases the risk of premature birth and other adverse outcomes of pregnancy...
Pre-pregnancy weight and the risk of stillbirth and neonatal deathJanni Kristensen
Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, 8200 Aarhus N, Denmark
BJOG 112:403-8. 2005..The present and other studies linking maternal obesity to an increased risk of severe adverse pregnancy outcomes emphasise the need for public interventions to prevent obesity in young women...
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc geneM Oshima
Banyu Tsukuba Research Institute Merck, Japan
Proc Natl Acad Sci U S A 92:4482-6. 1995..It is therefore unlikely that the truncated product interacts directly with the wild-type protein and causes the microadenomas by a dominant negative mechanism...
Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in miceE Georges-Labouesse
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, Illkirch, C U de Strasbourg, France
Nat Genet 13:370-3. 1996..Our study provides evidence that some forms of epidermolysis bullosa may originate from defects of the alpha 6 gene...
Cesarean section on request at 39 weeks: impact on shoulder dystocia, fetal trauma, neonatal encephalopathy, and intrauterine fetal demiseGary D V Hankins
The University of Texas Medical Branch, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Galveston, TX 77555 0587, USA
Semin Perinatol 30:276-87. 2006....
Exogenous shocks to the human sex ratio: the case of September 11, 2001 in New York CityR Catalano
School of Public Health, University of California, Berkeley, Berkeley, CA, USA
Hum Reprod 21:3127-31. 2006..We contribute to the literature by testing the association between the secondary sex ratio and the events of September 11 in New York City...
Racial variation in spontaneous fetal deaths at 20 weeks or older in upstate New York, 1980-86G M Buck
Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo 14214, USA
Public Health Rep 110:587-92. 1995..Using the fetal death certificate registry maintained by the New York State Department of Health, 8,592 spontaneous fetal deaths at ..
Severe hypotension and fetal death due to tocolysis with nifedipineA J van Veen
Department of Obstetrics and Gynaecology, University Hospital Groningen, PO Box 30001, 9700 RB Groningen, The Netherlands
BJOG 112:509-10. 2005
New indicator of quality of emergency obstetric and newborn careVincent Fauveau
Lancet 370:1310. 2007
Guidelines for investigating stillbirths: an update of a systematic reviewPaula Corabian
Institute of Health Economics, Edmonton AB
J Obstet Gynaecol Can 29:560-7. 2007..To identify formal, publicly available guidelines for stillbirth investigation and to identify the most appropriate clinical practice guideline (or component of a guideline) for use in Alberta...
Association of myocarditis with high viral load of porcine circovirus type 2 in several tissues in cases of fetal death and high mortality in piglets. A case studyInger M Brunborg
Section for Virology and Serology, National Veterinary Institute, N 0033 Oslo, Norway
J Vet Diagn Invest 19:368-75. 2007..Neither porcine parvovirus nor encepaholomyocarditis virus was detected. These results indicate that the PCV2 infection might have been of etiological importance for the fetal deaths and piglet mortality observed in this herd...
Prospective risk of stillbirth in multiple-gestation pregnancies: a population-based analysisShanthi Sairam
Feto-Maternal Medicine Unit, Academic Department of Obstetrics and Gynaecology, St George's Hospital Medical School, London, United Kingdom
Obstet Gynecol 100:638-41. 2002..Because multiple gestations rarely proceed beyond 39 weeks, and because stillbirth risk increases several-fold beyond this stage, elective delivery might be justified at this gestational age...
Guidelines for neuropathologic diagnostics of perinatal unexpected loss and sudden infant death syndrome (SIDS): a technical protocolLuigi Matturri
Institute of Pathology, University of Milan, Via della Commenda, Milan, Italy
Virchows Arch 452:19-25. 2008....
Advanced paternal age and risk of fetal death: a cohort studyAnne Marie Nybo Andersen
Department of Social Medicine, University of Copenhagen, Copenhagen, Denmark
Am J Epidemiol 160:1214-22. 2004..to the Danish National Birth Cohort from 1997 to 1999 to assess the association between paternal age and fetal death. Fathers of the pregnancies were identified by record linkage to population registers...
Interpregnancy interval and risk of preterm birth and neonatal death: retrospective cohort studyGordon C S Smith
Department of Obstetrics and Gynaecology, Cambridge University, Box The Rosie Hospital, Cambridge CB2 2QQ
BMJ 327:313. 2003..To determine whether a short interval between pregnancies is an independent risk factor for adverse obstetric outcome...
Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in miceZ F Huang
Division of Hematology, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO 63110, USA
Blood 90:944-51. 1997..Human TFPI-deficient embryos may suffer a similar fate because an individual with TFPI deficiency has not been identified...
The influence of obstetric intervention on trends in twin stillbirths: United States, 1989-99C V Ananth
Section of Epidemiology and Biostatistics, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08901-1977, USA
J Matern Fetal Neonatal Med 15:380-7. 2004....
Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine studyS E Vollset
Section for Medical Statistics, The Department of Public Health and Primary Health Care, Norway
Am J Clin Nutr 71:962-8. 2000..Total homocysteine (tHcy) measured in serum or plasma is a marker of folate status and a risk factor for cardiovascular disease...
Unexplained antepartum fetal deaths: what are the determinants?Rachana Chibber
Department of Obstetrics and Gynecology, King Faisal University Teaching Hospital, PO BOX 40126, 31952 Al Khobar, Kingdom of Saudi Arabia
Arch Gynecol Obstet 271:286-91. 2005The objective was to assess fetal, antenatal, and pregnancy determinants of unexplained antepartum fetal death.
Maternal and biochemical predictors of antepartum stillbirth among nulliparous women in relation to gestational age of fetal deathG C S Smith
Department of Obstetrics and Gynaecology, Cambridge University, Rosie Maternity Hospital, Cambridge, UK
BJOG 114:705-14. 2007..To determine whether maternal serum levels of alphafetoprotein (alpha-FP) and human chorionic gonadotrophin (hCG) at 15-21 weeks provided clinically useful prediction of stillbirth in first pregnancies...
Medical treatment for early fetal death (less than 24 weeks)J P Neilson
University of Liverpool, Division of Perinatal and Reproductive Medicine, First Floor, Liverpool Women s NHS Foundation Trust, Crown Street, Liverpool, UK L8 7SS
Cochrane Database Syst Rev 3:CD002253. 2006..can reveal abnormal findings during this phase by demonstrating anembryonic pregnancies or embryonic or fetal death. Treatment before 14 weeks has traditionally been surgical but medical treatments may be effective, safe, and ..
Fetal deathRobert M Silver
Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT 84132, USA
Obstet Gynecol 109:153-67. 2007..With improved care for conditions such as RhD alloimmunization, diabetes, and preeclampsia, the rate of fetal death in the United States decreased substantially in the mid twentieth century...
Complement C3 activation is required for antiphospholipid antibody-induced fetal lossV Michael Holers
Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
J Exp Med 195:211-20. 2002..Recent studies have shown that uncontrolled complement activation in the placenta leads to fetal death in utero...
Third-trimester unexplained intrauterine fetal death is associated with inherited thrombophiliaAriel Many
Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
Obstet Gynecol 99:684-7. 2002..These findings suggest that thrombophilia work-ups should be part of IUFD investigations and may have therapeutic and prognostic implications in future pregnancies...
Obstetric intervention, stillbirth, and preterm birthK S Joseph
Department of Obstetrics and Gynecology, Dalhousie University, Halifax, Nova Scotia, Canada
Semin Perinatol 26:250-9. 2002..Obstetric intervention at preterm gestation, when indicated, can prevent stillbirth and reduce infant morbidity and mortality despite the increasing rates of preterm delivery...
The epidemiology of stillbirthSven Cnattingius
Department of Medical Epidemiology, Karolinska Institutet, Stockholm
Semin Perinatol 26:25-30. 2002..The prevalence of delayed childbearing and, especially overweight, are increasing in most developed countries. The proportion of stillbirth attributable to overweight is likely to increase...
Perinatal outcome of quadruplet pregnancies in relation to chorionicityA L Adegbite
Department of Obstetrics and Gynecology, University of Manchester, St Mary s Hospital, Manchester, UK
J Perinatol 27:15-21. 2007..To compare the perinatal outcome of quadruplets in relation to chorionicity...
Is small for gestational age a marker of future fetal survival in utero?Hamisu M Salihu
Department of Obstetrics, Gynecology, and Reproductive Sciences, UMDNJ Robert Wood Johnson Medical School, New Brunswick 08901 1977, USA
Obstet Gynecol 107:851-6. 2006..We sought to assess whether small for gestational age is a risk factor for stillbirth of a subsequent sibling...
Pregnancy loss after first trimester viability in women with sickle cell trait: a preliminary reportMichelle Y Taylor
Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, Mississippi, USA
South Med J 101:150-1. 2008Traditionally, sickle cell trait has not been associated with a higher risk of fetal death, but we noted several, which led us to assess all such pregnancies.
Transplacental fetal treatment improves the outcome of prenatally diagnosed complete atrioventricular block without structural heart diseaseEdgar T Jaeggi
Division of Cardiology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
Circulation 110:1542-8. 2004..A standardized treatment approach, including maternal dexamethasone at CAVB diagnosis and beta-stimulation for fetal heart rates <55 bpm, has been used at our institutions since 1997. The study presents the impact of this approach...
Congenital malformations of the diaphragm: findings of the West Midlands Congenital Anomaly Register 1995 to 2000A Tonks
West Midlands Perinatal Institute, Birmingham, UK
Prenat Diagn 24:596-604. 2004..This presents significant challenges for those involved in counselling the parents of affected fetuses...
Improving outcomes in fetuses and neonates with congenital displacement (Ebstein's malformation) or dysplasia of the tricuspid valveDoff B McElhinney
Department of Cardiology, Children's Hospital Boston, Boston, Massachusetts, USA
Am J Cardiol 96:582-6. 2005..To improve outcomes in this group of high-risk patients, novel approaches to management may be indicated...
High perinatal survival in monoamniotic twins managed by prophylactic sulindac, intensive ultrasound surveillance, and Cesarean delivery at 32 weeks' gestationL Pasquini
Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
Ultrasound Obstet Gynecol 28:681-7. 2006....
Perinatal outcomes in monoamniotic gestationsH Roque
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Connecticut, Farmington, Connecticut 06030, USA
J Matern Fetal Neonatal Med 13:414-21. 2003....
Pregnancy loss rate following routine genetic amniocentesis at Wellington HospitalMichel Sangalli
Department of Obstetrics and Gynaecology, Wellington School of Medicine and Health Sciences CCDHB, Wellington Women s Hospital, Wellington, New Zealand
N Z Med J 117:U818. 2004..To determine the institutional pregnancy loss rate following second-trimester genetic amniocentesis...
Current outcome of antenally diagnosed cystic lung diseaseMark Davenport
Department of Paediatric Surgery, King's College Hospital, London, England, UK
J Pediatr Surg 39:549-56. 2004..The need for surgery should be based on appropriate postnatal investigations (eg, CT scans), rather than on antenatal behavior...
The outcome of twin pregnancies complicated by single fetal death after 20 weeks of gestationHalil Aslan
Department of Perinatology, SSK Bakirkoy Maternity and Children s Hospital, Istanbul, Turkey
Twin Res 7:1-4. 2004..twin births was conducted to evaluate the maternal and fetal outcomes of twin pregnancies complicated by single fetal death. The incidence of single fetal death in twin pregnancies after 20 weeks was 3.3%...
Pregnancy outcome in lupus nephropathyFarooq Z Rahman
Department of Medicine, The Whittington Hospital, Highgate Hill, London, UK
Arch Gynecol Obstet 271:222-6. 2005..Pregnant women with LN require intense fetal and maternal surveillance for the best outcomes of pregnancy...
Sacrococcygeal teratoma: prenatal assessment, fetal intervention, and outcomeHolly L Hedrick
Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA
J Pediatr Surg 39:430-8; discussion 430-8. 2004..Amnioreduction, cyst aspiration, and surgical debulking are potentially life-saving interventions...
Risk factors predisposing to abruptio placentae. Maternal and fetal outcomeSaad E Dafallah
Faculty of Medicine, University of Gezira, Medani, Sudan
Saudi Med J 25:1237-40. 2004..The study was designed as a case control study from live, singleton births and singleton fetal death. RESULTS: The total number of abruptio placentae collected during this period was 1028, while the total number ..
Pregnancy outcome in women with prosthetic heart valvesAnwar H Nassar
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Lebanon
Am J Obstet Gynecol 191:1009-13. 2004..Despite a high maternal morbidity rate, the perinatal outcome is acceptable when pregnancy progresses beyond the first trimester...
Usefulness of a placental profile in high-risk pregnanciesMeghana Toal
Department of Obstetrics and Gynecology, Placenta Clinic, Maternal Fetal Medicine Division, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
Am J Obstet Gynecol 196:363.e1-7. 2007....
Intrauterine growth restriction and absent or reverse end-diastolic blood flow in umbilical artery (Doppler class II or III): A retrospective study of short- and long-term fetal morbidity and mortalityStefan Gerber
Department of Obstetrics and Gynecology, University Hospital of Lausanne, Maternity CHUV, 1011 Lausanne, Switzerland
Eur J Obstet Gynecol Reprod Biol 126:20-6. 2006..The optimal timing of delivery is still controversial. We studied the short- and long-term morbidity and mortality among these children associated with our defined management...
Dispelling the preconceived notion that lupus pregnancies result in poor outcomesJill P Buyon
J Rheumatol 32:1641-2. 2005
Pregnancy outcome in women with pre-existing lupus nephritisL Soubassi
Department of Nephrology, Alexandra Hospital, Athens, Greece
J Obstet Gynaecol 24:630-4. 2004..Pregnancy is not contraindicated in women with lupus nephritis, but is associated with significant fetal and maternal risks...
The influence of race on fetal outcomeCindy L Allen
Medical University of South Carolina, College of Nursing, Charleston, South Carolina 29425, USA
Am J Perinatol 22:245-8. 2005The purpose of this study was to examine racial differences in fetal death by gestational age among South Carolinians during 1999 to 2000 in an attempt to identify sociodemographic risk factors that may contribute to the refinement of ..
Vitamins C and E and the risks of preeclampsia and perinatal complicationsAlice R Rumbold
Discipline of Obstetrics and Gynaecology, University of Adelaide, Women's and Children's Hospital, North Adelaide, Australia
N Engl J Med 354:1796-806. 2006..Controlledtrials.com number, ISRCTN00416244.)...
The relationship between perinatal outcome of singleton pregnancies and isolated highly elevated levels of maternal serum human chorionic gonadotropin at mid-gestationOren Tavor
Department of Pediatrics, Dana Children s Hospital, Tel Aviv, Israel
Isr Med Assoc J 9:509-12. 2007..The measurement of maternal serum human chorionic gonadotropin as a predictor of fetuses with Down syndrome has been in use since 1987...
Research Grants
- Neonatal Long QT Syndrome and Sudden Infant DeathAlfred L George; Fiscal Year: 2010..Additional anecdotal evidence indicates that LQTS may also present as intrauterine fetal death (IUFD)...
- Neonatal Long QT Syndrome and Sudden Infant DeathALFRED GEORGE; Fiscal Year: 2009..Additional anecdotal evidence indicates that LQTS may also present as intrauterine fetal death (IUFD)...
- Neonatal Long QT Syndrome and Sudden Infant DeathALFRED GEORGE; Fiscal Year: 2007..Additional anecdotal evidence indicates that LQTS may also present as intrauterine fetal death (IUFD)...
- Air Pollution and Adverse Birth OutcomesBeate Ritz; Fiscal Year: 2004..of proximity to high traffic density roadways; (2) short-term increases in air pollution prior to birth or fetal death and/or medium-term exposures accumulated over months or trimesters of pregnancy are more important; (3) ..
- Triggers of Abruptio Placentae - A Case Crossover Study of an Ischemic PlacentalMICHELLE A contact WILLIAMS; Fiscal Year: 2010..large part because of its association with adverse outcomes in newborns and mothers including preterm delivery, fetal death, maternal hemorrhagic shock, and renal failure...
- Child Health After Assisted Reproductive Technology: A Population-Based StudyBARBARA JOAN LUKE; Fiscal Year: 2010..link ART clinical data from 2004 to 2011 to the Massachusetts Pregnancy to Early Life Longitudinal birth and fetal death file (resulting in approximately 18,000 ART assisted births, 5,000 births with no ART but other subfertility ..
- Plurality and Contemporary Infant Mortality RisksBarbara Luke; Fiscal Year: 2006..g., weight discordance, gender mix, fetal death of a sibling)...
- Renal Transporters and Fetal NeuroendocrinologyCharles Wood; Fiscal Year: 2009..PUBLIC HEALTH RELEVANCE: Fetal stress is a prevalent cause of fetal death and morbidity in utero...
- Renal Transporters and Fetal NeuroendocrinologyCharles Wood; Fiscal Year: 2009..PUBLIC HEALTH RELEVANCE: Fetal stress is a prevalent cause of fetal death and morbidity in utero...
- Renal Transporters and Fetal NeuroendocrinologyCharles E Wood; Fiscal Year: 2010..PUBLIC HEALTH RELEVANCE: Fetal stress is a prevalent cause of fetal death and morbidity in utero...
- A Model Statewide Trial to Detect and Treat Maternal Hypothyroidism in PregnancyJames Haddow; Fiscal Year: 2007..g., fetal death, prematurity, preeclampsia)...
- Mechanisms of aPL antibody-induced pregnancy lossJane Salmon; Fiscal Year: 2007..Pregnancy complications in women with APS include fetal death, preeclampsia, and intrauterine growth restriction (IUGR)...
- Mechanism of aPL antibody-induced Pregnancy lossJane E Salmon; Fiscal Year: 2010..Pregnancy complications in women with APS include fetal death, preeclampsia, and intrauterine growth restriction (IUGR)...
- Mechanism of aPL antibody-induced Pregnancy lossJane Salmon; Fiscal Year: 2009..Pregnancy complications in women with APS include fetal death, preeclampsia, and intrauterine growth restriction (IUGR)...
- ANTICARDIOLIPIN ANTIBODIES AND OXIDIZED PHOSPHOLIPIDSJoseph Witztum; Fiscal Year: 2000..and/or the lupus anticoagulant and clinically experience recurrent venous or arterial thrombosis, history of fetal death and autoimmune thrombocytopenia...
- ANTICARDIOLIPIN ANTIBODIES AND OXIDIZED PHOSPHOLIPIDSJoseph Witztum; Fiscal Year: 2004..and/or the lupus anticoagulant and clinically experience recurrent venous or arterial thrombosis, history of fetal death and autoimmune thrombocytopenia...
- Prolactin regulation of decidual activin and apoptosisJennifer Bowen Shauver; Fiscal Year: 2003..decidualization during early pregnancy, in the presence of exogenous progesterone, but are infertile due to fetal death and resorption from midpregnancy...
- Reprogramming of X-linked genes by nuclear transferX Tian; Fiscal Year: 2003..Abnormal XCI has been found to have deleterious effect on placental growth and causes fetal death. The abnormal XCI may be caused by the impaired ability of cloned embryos to erase epigenetic marks of XCI in ..
- FAILURE TO MODULATE T & NK CELL ZETA EXPRESSION IN RSADouglas Taylor; Fiscal Year: 2005..NK and T cell dysfunction in some pregnant women could be for poor pregnancy outcomes from pre-term labor to fetal death. Understanding the mechanisms of pregnancy-associated T and NK cell dysfunction will provide the greatest ..
- MISOPROSTOL FOR TREATMENT OF FETAL DEATH AT 14-28 WEEKS PHASE IIIBeverly Winikoff; Fiscal Year: 2007The proposed project is a Phase 3 trial of the drug misoprostol for the treatment of fetal death at 14 to 28 weeks of pregnancy, inclusive...
- Regulation of Trophoblast Differentiation and FunctionYoel Sadovsky; Fiscal Year: 2010..PPARY-null mouse embryos exhibit intrauterine growth restriction and subsequently fetal death, associated with diminished fat accumulation within the labyrinthine placenta...
- Regulation of Trophoblast Differentiation and FunctionYoel Sadovsky; Fiscal Year: 2007..PPARY-null mouse embryos exhibit intrauterine growth restriction and subsequently fetal death, associated with diminished fat accumulation within the labyrinthine placenta...
- Regulation of Trophoblast Differentiation and FunctionYoel Sadovsky; Fiscal Year: 2005..3) PPARy -I- embryos exhibit intrauterine growth restriction and subsequently fetal death, associated with diminished size of fat globules within the labyrinthine placenta...
- Burden of Malaria in Pregnancy in IndiaDavidson Hamer; Fiscal Year: 2007..Malaria in pregnancy (MIP) is associated with an increased risk of fetal death, prematurity, intrauterine growth retardation (IUGR), low birth weight (LBW), and maternal anemia...
- THE IMPACT OF AIRBORNE PARTICULATES ON INFANT HEALTHKENNETH CHAY; Fiscal Year: 2005..Detail Files, National Natality Detail Files, Linked Birth and Infant Death Public-use Data Files, and the Fetal Death Data Public-use Data Files...
