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| vaginal neoplasmsSummarySummary: Tumors or cancer of the VAGINA. Top Publications
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Publications
Vaginal dysplastic lesions in women with hysterectomy and receiving radiotherapy are linked to high-risk human papillomavirusLuisa Barzon
Department of Histology, Microbiology, and Medical Biotechnologies, University of Padova, Padova, Italy
J Med Virol 67:401-5. 2002..Whereas colposcopic examination can detect these preneoplastic lesions, HPV genotyping is a sensitive, inexpensive, and noninvasive method that may complement colposcopy and the PAP test...
Effect of human papillomavirus vaccines on vulvar, vaginal, and anal intraepithelial lesions and vulvar cancerMonika Hampl
Department of Gynecology and Obstetrics, Institute of Pathology, University Hospital, Heinrich Heine University, Duesseldorf, Germany
Obstet Gynecol 108:1361-8. 2006..We assessed the prevalence of HPV (and the types) to estimate the possible effect of a HPV vaccine on lower genital tract disease prevention...
Blue nevi of the Müllerian tract: case series and review of the literatureKenneth J Craddock
Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Low Genit Tract Dis 11:284-9. 2007..Because of their rarity (3 previous cases in the literature), vaginal blue nevi have not previously been studied with immunohistochemical and ultrastructural analysis...
The distribution of low and high-risk HPV types in vulvar and vaginal intraepithelial neoplasia (VIN and VaIN)Monica Srodon
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
Am J Surg Pathol 30:1513-8. 2006..Finally, comparison of the distribution of HPV in the vagina and vulva suggests that VaIN is more closely related to cervical intraepithelial neoplasia than to VIN...
Sentinel node detection in a patient with recurrent endometrial cancer initially treated by hysterectomy and radiotherapyP van Dam
Department of Obstetrics and Gynecology, Sint Augustinus Hospital, Antwerp, Belgium
Int J Gynecol Cancer 14:673-6. 2004..This unique case shows that sentinel node detection is possible after previous radiotherapy and surgery and hopes to stimulate further research in this field...
Definitive radiotherapy for patients with isolated vaginal recurrence of endometrial carcinoma after hysterectomyAnuja Jhingran
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 56:1366-72. 2003..To determine the outcome of patients after radical radiotherapy (RT) for isolated vaginal recurrence of endometrial carcinoma and to determine the clinical and pathologic predictors of outcome...
The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the endometriumS Nag
The Ohio State University, Columbus, OH 43210, USA
Int J Radiat Oncol Biol Phys 48:779-90. 2000..To develop recommendations for use of high-dose-rate (HDR) brachytherapy in patients with endometrial cancer...
Incidence of squamous neoplasia of the cervix and vagina in women exposed prenatally to diethylstilbestrol (United States)E E Hatch
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Cancer Causes Control 12:837-45. 2001..The purpose of the current study was to evaluate the long-term risk of developing high-grade squamous neoplasia of the genital tract among women exposed prenatally to DES...
High dose rate (192)Ir afterloading brachytherapy for cancer of the vaginaD M Kushner
Department of Obstertrics and Gynecology, University of Wisconsin Hospital and Clinics, H4/636 CSC, 600 Highland Avenue, Madison, WI 53792-3236, USA
Br J Radiol 76:719-25. 2003..Long-term follow-up is needed to further assess late complications, and larger studies are needed to confirm our results...
Sentinel node biopsy in vulvar and vaginal melanoma: presentation of six cases and a literature reviewLiana Abramova
Department of Surgery, University of Virginia Health Science Center, Charlottesville, Virginia 22906, USA
Ann Surg Oncol 9:840-6. 2002..CONCLUSIONS: This experience, plus reports of a small number of patients from three similar studies, supports the impression that sentinel lymph node biopsy is feasible for vulvar and vaginal melanoma...
Cancer and developmental exposure to endocrine disruptorsLinda S Birnbaum
Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina, USA
Environ Health Perspect 111:389-94. 2003..Implications of these new findings suggest that causes of endocrine-related cancers or susceptibility to cancer may be a result of developmental exposures rather than exposures existing at or near the time of tumor detection...
Sentinel node detection in patients with vaginal carcinomaPeter Van Dam
Department of Obstetrics and Gynecology, Sint Augustinus Hospital, Antwerp, Belgium
Gynecol Oncol 92:89-92. 2004..The objective was to describe sentinel ode detection in patients with primary and recurrent vaginal carcinoma...
Interstitial brachytherapy for salvage treatment of vaginal recurrences in previously unirradiated endometrial cancer patientsSubir Nag
Division of Radiation Oncology, Arthur G James Cancer Hospital and Solove Research Institute, Ohio State University, 300 W Tenth Avenue, Columbus, OH 43210, USA
Int J Radiat Oncol Biol Phys 54:1153-9. 2002..To evaluate whether interstitial brachytherapy can effectively salvage vaginal recurrence from endometrial carcinoma...
High-dose-rate (HDR) brachytherapy with or without external beam radiotherapy in the treatment of primary vaginal carcinoma: long-term results and side effectsUlrike Mock
Department of Radiotherapy and Radiobiology, University Hospital Vienna, Vienna, Austria
Int J Radiat Oncol Biol Phys 56:950-7. 2003..To report toxicity, prognostic factors, and outcome of HDR brachytherapy in the primary management of vaginal carcinoma...
Salvage treatment with high-dose-rate brachytherapy for isolated vaginal endometrial cancer recurrencePatrick Petignat
Department of Gynecologic Oncology, , , , Canada
Gynecol Oncol 101:445-9. 2006..Four patients (18%) presented grades 3-4 gastrointestinal toxicity, and 11 (50%), grade 3 vaginal toxicity. CONCLUSION: Recurrent vaginal endometrial cancer is amenable to salvage therapy with HDRB and EBRT...
Comprehensive analysis of 130 multicentric intraepithelial female lower genital tract lesions by HPV typing and p16 expression profileMonika Hampl
Department of Gynecology and Obstetrics, University Hospital of Duesseldorf, Moorenstr 5, 40 225 Duesseldorf, Germany
J Cancer Res Clin Oncol 133:235-45. 2007..In the current study, HPV infections and oncogene expression were assessed in a large series of patients with multicentric lower genital tract disease to analyze the transformation steps in extracervical disease...
High-dose-rate interstitial brachytherapy for gynecologic malignanciesSushil Beriwal
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
Brachytherapy 5:218-22. 2006..The study aimed to assess the outcome of locally advanced cervical and vaginal cancer treated with high-dose-rate interstitial brachytherapy (HDRB)...
[Clinical analysis of 42 cases of primary malignant melanoma in female genital tract]Ju Sheng An
Department of Gynecologic Oncology, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China
Zhonghua Fu Chan Ke Za Zhi 42:320-4. 2007..To analyze the clinical characteristics, diagnosis, treatment and prognosis of primary malignant melanoma in female genital tract...
Evaluating patients with mildly elevated transaminase levelsKimberly A Burns
Laura Lee Blanton Gynecologic Oncology Center, University of Texas M D Anderson Cancer Center, Houston, USA
Clin J Oncol Nurs 11:499-502. 2007..At completion, her CA-125 normalized and imaging studies showed no evidence of disease. However, within three months, her CA-125 was elevated and a palpable mass at the vaginal apex was proven by biopsy to be recurrent disease...
Incidental diagnosis of primary vaginal adenocarcinoma of intestinal type: a case report and review of the literatureAntonino Ditto
Department of Gynecologic Oncology, Istituto Nazionale Tumori, Milan, Italy
Int J Gynecol Pathol 26:490-3. 2007..Concomitant chemoradiation, as a primary treatment, should be considered...
[Diagnosis of vulval and vaginal neoplasms with magnetic resonance imaging]E A Hauth
Institut fur Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitatsklinikum Essen, Essen, Deutschland
Gynakol Geburtshilfliche Rundsch 47:226-35. 2007..MRI is useful in the pretherapeutic staging of vulval and vaginal neoplasms in order to assess tumor size, local tumor extent and presence of lymph node metastases...
MR imaging features of vaginal malignanciesJyoti H Parikh
Department of Radiology, Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom
Radiographics 28:49-63; quiz 322. 2008..Most vaginal metastases occur by means of direct local spread from the cervix, uterus, or rectum. The MR imaging appearances of these metastases reflect the MR imaging appearances of the primary tumor...
Stage II adenocarcinoma of the endometrium: adjuvant radiotherapy and recurrence patternsScott C Cozad
Therapeutic Radiologists, Inc, Liberty Radiation Oncology Clinic, Liberty, MO 64068, USA
Int J Radiat Oncol Biol Phys 71:205-12. 2008..Review patterns of recurrence for Stage II endometrial cancer in a community practice...
Early-stage vaginal carcinoma--an analysis of 70 patientsG R Otton
Queensland Centre for Gynaecological Cancer, Royal Women s Hospital, Brisbane, Australia
Int J Gynecol Cancer 14:304-10. 2004..The aims of this study were to assess outcomes and define prognostic factors for early-stage vaginal carcinoma...
Protein expression patterns in primary carcinoma of the vaginaK Hellman
Department of Gynecologic Oncology, Radiumhemmet, Karolinska Hospital, S 171 76 Stockholm, Sweden
Br J Cancer 91:319-26. 2004..There might, further, be a possibility to identify tumour-specific markers among the proteins that are differentially expressed. The results from this study have to be confirmed by more comprehensive studies in the future...
Predictors for long-term survival after interdisciplinary salvage surgery for advanced or recurrent gynecologic cancersM C Fleisch
Universitaets Frauenklinik, Heinrich Heine Universitaet, Duesseldorf, Germany
J Surg Oncol 95:476-84. 2007..We wanted to identify factors which allow predicting long-term survival after pelvic exenteration (PE) for locally advanced or recurrent gynecologic malignancies...
Rectovaginal radiation fistula repair using an obturator fasciocutaneous thigh flapRaphael C Lee
Section of Plastic Surgery, Department of Surgery, The University of Chicago, 5812 South Ellis Avenue, Chicago, IL 60637, USA
Gynecol Oncol 94:277-82. 2004..Most often, either permanent colostomy or reconstruction with a well-vascularized flap is necessary. Traditional techniques for fistula repair utilize bulky muscle flaps, disfiguring pudendal artery flaps or may require laparotomy...
MRI of vaginal conditionsC Lopez
Department of Radiology, Birmingham Women s Hospital, Birmingham, UK
Clin Radiol 60:648-62. 2005..In this paper, examples of the above are described and illustrated together with examples of the much rarer primary vaginal malignancies...
Definitive radiation therapy for squamous cell carcinoma of the vaginaSteven J Frank
Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 62:138-47. 2005..Brachytherapy plays an important role in the treatment of many vaginal cancers but should be carefully selected and applied to obtain optimal coverage of the target volume...
Predictors of vaginal relapse in stage I endometrial cancerAndrea Mariani
Section of Gynecologic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Gynecol Oncol 97:820-7. 2005..The cost and morbidity of vaginal brachytherapy should be balanced against the potential risk of vaginal relapse in this group of patients...
Management of a case of primary vaginal cancer with irreducible massive uterine prolapse--a case reportA Karateke
Department of Gynecological Oncology, Zeynep Kamil Women's and Children's Health and Education and Research Hospital, Istanbul, Turkey
Eur J Gynaecol Oncol 27:528-30. 2006..The cervix was bilaterally suspended to the pectineal ligaments by polypropylene mesh...
Recurrent endometrial cancer: patterns of recurrent disease and assessment of prognosisS A Sohaib
Department of Radiology, Royal Marsden Hospital, London, UK
Clin Radiol 62:28-34; discussion 35-6. 2007..To evaluate patterns of disease and identify factors predicting outcome in patients presenting with recurrent endometrial adenocarcinoma following primary surgery...
Recurrence in a Schuchardt incision after Schauta-Amreich radical vaginal hysterectomy for cervical cancerA A Bader
Department of Obstetrics and Gynecology, Medical University of Graz, Auenbruggerplatz 14, A 8036 Graz, Austria
Int J Gynecol Cancer 16:1479-81. 2006..Cervical cancers can implant and recur in perineal incisions. Thus, it appears prudent to avoid such incisions or, if they are made, to irrigate them copiously before closing them...
Small cell carcinoma of the female genital tractSara Crowder
Mid Missouri Gynecologic Oncology, Columbia, MO 65201, USA
Semin Oncol 34:57-63. 2007..Indeed, the majority of patients have an early demise with extensive distant disease. We review the clinical features, evaluation, and management of SCC of the female genital tract based on a comprehensive review of the literature...
Gynecologic cancers: factors affecting survival after pulmonary metastasectomyJose M Clavero
Division of General Thoracic Surgery, Rochester, Minnesota, USA
Ann Thorac Surg 81:2004-7. 2006..Both a short disease-free interval between the primary gynecologic procedure and pulmonary metastasectomy, and a primary cervical tumor had an adverse effect on survival...
Vaginal cancer in a patient treated for cervical intraepithelial neoplasia (CIN 3): case reportG Androutsopoulos
Department of Obstetrics and Gynecology, Patras University Hospital, Rion, Greece
Eur J Gynaecol Oncol 27:638-9. 2006..In women who have undergone total hysterectomy for cervical intraepithelial neoplasia or cervical cancer, postoperative cytologic and colposcopic follow-up of the vagina is necessary...
A prospective study of the accuracy of 18Fluorodeoxyglucose positron emission tomography (18FDG PET) in identifying sites of metastasis prior to pelvic exenterationAmreen Husain
Stanford University School of Medicine, Div of Gynecologic Oncology and Memorial Sloan Kettering Cancer Center, USA
Gynecol Oncol 106:177-80. 2007..To determine the accuracy of (18)FDG PET in identifying sites of metastatic disease prior to pelvic exenteration or radical resection in patients (pts) with recurrent cervical or vaginal cancers...
Predictors of severe gastrointestinal toxicity after external beam radiotherapy and interstitial brachytherapy for advanced or recurrent gynecologic malignanciesMohit Kasibhatla
Department of Radiation Oncology, Dartmouth Hitchcock Medical Center, Hanover, NH 03756, USA
Int J Radiat Oncol Biol Phys 65:398-403. 2006..0...
The role of interstitial brachytherapy in the treatment of vaginal and vulvar malignanciesAnnedore R Seeger
Department of Radiation Oncology, University of Erlangen Nuremberg, Erlangen, Germany
Strahlenther Onkol 182:142-8. 2006..Irradiation has established itself as a treatment for vulvar and vaginal malignancies. Due to the sensitive nature of the vulvar and vaginal tissues, interstitial brachytherapy (iBT) provides an effective, gentle and individualized therapy...
Prognostic factors for outcomes and complications for primary squamous cell carcinoma of the vagina treated with radiationPhuoc T Tran
Department of Radiation Oncology, Stanford Cancer Center, 875 Blake Wilbur Drive, Stanford, CA 94305, USA
Gynecol Oncol 105:641-9. 2007..To analyze the results of treatment and identify prognostic factors for primary squamous cell carcinoma (SCCA) of the vagina managed with radiotherapy at a single institution...
Is cytologic screening an effective surveillance method for detection of vaginal recurrence of uterine cancer?Amy L Cooper
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky Chandler Medical Center, Lexington, Kentucky 40536 0298, USA
Obstet Gynecol 107:71-6. 2006..The study objective was to assess the efficacy and costs associated with Pap tests in routine surveillance of women with uterine cancer...
Surgically (laparotomy/laparoscopy) guided placement of high dose rate interstitial irradiation catheters (LG-HDRT): technique and outcomeJames W Orr
Florida Gynecologic Oncology, Lee Cancer Care, 2780 Cleveland Ave, Suite 717, Ft Myers, FL 33919, USA
Gynecol Oncol 100:145-8. 2006....
Upper vaginectomy for the treatment of vaginal intraepithelial neoplasiaMegan D Indermaur
Department of Gynecology Onclogy, University of South Florida, Tampa, FL, USA
Am J Obstet Gynecol 193:577-80; discussion 580-1. 2005..CONCLUSION: In our patients, upper vaginectomy was efficacious for the treatment of VAIN. The procedure led to the diagnosis of occult invasive cancer in 12% of these women...
Healing of vulvo-vaginal radionecrosis following revascularizationKaren E Hoffman
Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA
Gynecol Oncol 106:262-4. 2007..Patient factors affect non-malignant tissue tolerance to radiation exposure...
Magnetic resonance-guided interstitial therapy for vaginal recurrence of endometrial cancerAkila N Viswanathan
Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 66:91-9. 2006..To evaluate the feasibility and to describe the acute toxicity of a real-time intraoperative magnetic resonance (MR)-image guided interstitial approach to treating vaginal recurrence of endometrial cancer...
Primary mucinous adenocarcinoma of the vagina: possibility of differentiating from metastatic adenocarcinomasMaki Saitoh
Department of Pathology, Yamagata University School of Medicine, Yamagata, Japan
Pathol Int 55:372-5. 2005..These findings indicate that the mucinous adenocarcinoma arose from vaginal adenosis. Further studies are necessary to investigate whether lack of sulfomucin expression is a characteristic feature of vaginal adenosis...
Gynecologic malignancies in women aged less than 25 yearsWhitney You
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, Washington, DC 20307, USA
Obstet Gynecol 105:1405-9. 2005..Health maintenance programs for patients in this age group should continue to include pelvic exams and Pap test screening...
Hormonal replacement therapy after gynaecological cancerNicoletta Biglia
Institute for Cancer Research and Treatment IRCC, Academic Department of Gynaecological Oncology, University of Turin, Candiolo, Italy
Gynakol Geburtshilfliche Rundsch 46:191-6. 2006..The use of HRT in breast cancer patients is, at present, considered contra-indicated, even if results of clinical trials are not concordant. Therapeutic non-hormonal alternatives may be proposed to these patients...
Aggressive angiomyxoma of the vulva and vagina. A common problem: misdiagnosisTayfun Gungor
Department of Oncology, Zekai Tahir Burak Women s Health Education and Research Hospital, Ankara, Turkey
Eur J Obstet Gynecol Reprod Biol 112:114-6. 2004..Unfortunately, the pathological evaluation of the specimens revealed aggressive angiomyxoma. Misdiagnosis of this tumor is a common problem...
Polymorphous low-grade adenocarcinoma of the vulva and vagina: a tumor resembling adenoid cystic carcinomaStephanie Young
Department of Pathology, Cook County Hospital, Chicago, IL 60612, USA
Int J Surg Pathol 11:43-9. 2003..PLGA should be added to the differential diagnosis of vulvar and vaginal neoplasia...
Radiotherapy alone for invasive vaginal cancer: outcome with intracavitary high dose rate brachytherapy versus conventional low dose rate brachytherapyH Kucera
Department of Gynecology, University of Vienna, Vienna, Austria
Acta Obstet Gynecol Scand 80:355-60. 2001..CONCLUSION: With HDRB and its advantages of decreased radiation exposure and patient immobilization and precise positioning, treatment results to be obtained are at least similar to traditional LDRB for primary vaginal cancer...
Lymphovascular space invasion does not predict vaginal relapses in stage I endometrioid adenocarcinoma of the endometriumLaurephile Desrosiers
Department of Pathology, University of Massachusetts Medical Center, Worcester, MA 01605, USA
Ann Diagn Pathol 12:112-7. 2008..However, LVSI does not denote an increased likelihood of vaginal recurrences in S1EE. The presence of LVSI should not, in of itself, alter clinical staging, or trigger unnecessary therapeutic intervention...
Tumor cell spillage to the vaginal cavity and vaginal stump during the surgery of endometrial carcinomaE Ryo
Department of Obstetrics and Gynecology, Musashino Red Cross Hospital, and University of Tokyo, Tokyo, Japan
Acta Obstet Gynecol Scand 80:364-7. 2001..CONCLUSIONS: Endometrial carcinoma cells were spilled into the vaginal cavity in not a few cases and their spillage from there to the vaginal stump could follow during the surgery...
Lymphatic mapping and sentinel node biopsy in gynecological cancers: a critical review of the literatureAli Ayhan
Department of Obstetrics and Gynecology, Division of Gynaecological Oncology, Baskent University School of Medicine, Ankara, Turkey
World J Surg Oncol 6:53. 2008....
Radiation therapy for gynecologic cancerKrishnansu Sujata Tewari
Division of Gynecologic Oncology, The University of California, Irvine 92868, USA
J Obstet Gynaecol Res 28:123-40. 2002
Radiation therapy in endometrial cancerW J Koh
Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA 98195, USA
Best Pract Res Clin Obstet Gynaecol 15:417-32. 2001..In the meantime, we propose guidelines for radiotherapy in endometrial cancer which serve as bases for discussion and collaboration among physicians and as platforms for future study and progress...
Radiographic imaging in gynecologic oncologyJ T Soper
Division of Gynecologic Oncology, Box 3079, Duke University Medical Center, Durham, NC 27710, USA
Clin Obstet Gynecol 44:485-94. 2001..Further refinements of currently available techniques or newer techniques, however, are needed to increase the sensitivity for detection of subclinical or microscopic metastases in patients with gynecologic malignancies...
Ultrasound-guided interstitial brachytherapy in the treatment of advanced vaginal recurrences from cervical and endometrial carcinomaHajo Dirk Weitmann
Universitätsklinik für Strahlentherapie und Strahlenbiologie, Allgemeines Krankenhaus der Stadt Wien, Wahringer Gurtel 18 20, 1090 Vienna, Austria
Strahlenther Onkol 182:86-95. 2006..In advanced vaginal recurrences of cervical and endometrial carcinomas therapeutic options are rare because of preceding therapy...
Outcome and patterns of failure in pathologic stages I-IV clear-cell carcinoma of the endometrium: implications for adjuvant radiation therapyKevin T Murphy
Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
Int J Radiat Oncol Biol Phys 55:1272-6. 2003..To evaluate the outcome and patterns of failure in women with uterine clear-cell carcinoma and discuss implications for adjuvant radiation therapy (RT)...
Cancer of the urinary bladder neovagina in a patient with Morris' syndromeMiroslaw Wielgos
1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland
Onkologie 31:53-5. 2008..Vaginal agenesis is a rare condition, therefore the incidence of a malignant transformation in the neovagina is extremely low...
Time trends in the incidence of cervical and other genital squamous cell carcinomas and adenocarcinomas in Sweden, 1958-1996Kari Hemminki
Department of Biosciences at Novum, Karolinska Institute, CNT Novum, 141 57 Huddinge, Sweden
Eur J Obstet Gynecol Reprod Biol 101:64-9. 2002..We wanted to examine reasons for the different incidence trends for cervical squamous cell carcinoma (SCC, declining) and adenocarcinoma (increasing)...
Low-grade endometrial stromal sarcoma with florid intravenous componentKeith Wing Kit Lo
Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, SAR, China
Gynecol Obstet Invest 66:8-11. 2008..Search for tumor involvement of the venous system at the time of diagnosis of metastasis or recurrence is essential. Surgical management of extensive venous recurrence of LGESS is feasible...
[Sentinel lymph notes in female reproductive tract cancer]Jing-he Lang
Department of Obstetrics and Gynecology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 25:377-80. 2003..Any definitive statements can be made to the validity of sentinel lymphadenectomy until we got data with long-term follow-up...
A comparative analysis of human papillomavirus types 16 and 18 and expression of p53 gene and Ki-67 in cervical, vaginal, and vulvar carcinomasYasuko Koyamatsu
Department of Obstetrics and Gynecology, Saga Medical School, Nabeshima, Saga, Japan
Gynecol Oncol 90:547-51. 2003..This study aimed to investigate the correlation between HPV positivity, p53 overexpression, and cell proliferative activity in cervical, vaginal, and vulvar squamous cell carcinoma...
Sentinel lymph nodes in gynaecological malignancies: frontline between TNM and clinical staging systems?Katalin Zambo
Department of Nuclear Medicine, Faculty of Medicine, University of Pecs, Pecs, Hungary
Eur J Nucl Med Mol Imaging 30:1684-8. 2003..The authors believe that sentinel node sampling is in fact a beneficial method in both early and advanced stage disease for determination of the tumour status and individualisation of surgical interventions...
Laparoscopic radical hysterectomy with vaginectomy and reconstruction of vagina in patients with stage I of primary vaginal carcinomaBin Ling
Department of Obstetrics and Gynecology, Anhui Provincial Hospital and Anhui Medical University, Hefei 230001, China
Gynecol Oncol 109:92-6. 2008....
Laparoscopic-assisted radical parametrectomy including pelvic and/or paraaortic lymphadenectomy in women after prior hysterectomy-three casesYoon S Lee
Department of Obstetrics and Gynecology, Kyungpook National University, School of Medicine, 50 Samduk 2 Ga, Taegu, Korea 700 412
Gynecol Oncol 91:619-22. 2003..This type of surgery for invasive cervical cancer after a hysterectomy or vaginal stump metastasis traditionally requires a major laparotomy; however, a minimal-access approach is now being applied to this type of procedure...
Transperineal high-dose-rate interstitial radiation therapy in the management of gynecologic malignanciesJun Itami
Department of Radiation Therapy and Oncology, International Medical Center of Japan, Tokyo, Japan
Strahlenther Onkol 179:737-41. 2003..Clinical experience in high-dose-rate interstitial radiation therapy was retrospectively investigated...
Successful treatment of a high-grade intraepithelial neoplasia with imiquimod, with vulvar pemphigus as a side effectG Campagne
Department of Obstetrics and Gynecology, Clinica Bella Medica, Partida Cap Negret 17, 03590 Altea, Spain
Eur J Obstet Gynecol Reprod Biol 109:224-7. 2003..The posterior biopsies confirm the absence of lesions but show drug-induced pemphigus as a side effect...
Vaginal neoplasms in infancy: the combined role of chemotherapy and conservative surgical resectionC R McHenry
Division of Pediatric Surgery, Children s Memorial Hospital, Chicago, IL 60614
J Pediatr Surg 23:842-5. 1988..One required a partial vaginectomy for local recurrence 21 months after initial presentation. Both patients are alive and disease-free 18 months and 4 years after surgery...
Alcoholism and risk for cancer of the cervix uteri, vagina, and vulvaE Weiderpass
International Agency for Research on Cancer, Lyon, France
Cancer Epidemiol Biomarkers Prev 10:899-901. 2001..We conclude that alcoholic women are at high risk for in situ and invasive cervical cancer and for cancer of the vagina...
The prevalence of tumors of the breast and female genital tract in ItalyM Sant
Epidemiology Division, National Cancer Institute (INT, Milan, Italy
Tumori 85:382-6. 1999..The prevalence of corpus uteri cancer decreased slightly in the elderly only, whereas that of cervix uteri cancer decreased at all ages...
Risk of anogenital cancer after diagnosis of cervical intraepithelial neoplasia: a prospective population-based studyGustaf Edgren
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
Lancet Oncol 8:311-6. 2007..Associations between HPV and vaginal, vulvar, and anal cancers are well established, but the full extent in terms of age and time since diagnosis of these associations is not well known...
A population-based study of squamous cell vaginal cancer: HPV and cofactorsJanet R Daling
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109 1024, USA
Gynecol Oncol 84:263-70. 2002..We conducted a study to evaluate risk factors for in situ and invasive vaginal cancer and their potential relationship to prior exposure to human papillomaviruses (HPV)...
Descriptive epidemiology of vulvar and vaginal cancers in Vaud, Switzerland, 1974-1994F Levi
Institut Universitaire de Medecine Sociale et Preventive, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Ann Oncol 9:1229-32. 1998..To analyse trends in incidence, survival and risk of second neoplasms following vaginal and vulvar cancers using data collected by the Swiss Cancer Registry of Vaud over the 21-year period 1974-1994...
Leiomyosarcoma of the vagina: a case report and review from the literatureMin Jung Suh
Department of Obstetrics and Gynecology, St Vincent s Hospital, The Catholic University of Korea, Suwon, Korea
J Gynecol Oncol 19:261-4. 2008Leiomyosarcomas comprise fewer than 2% of all malignant vaginal neoplasms. Due to their rarity, treatment for vaginal leiomyosarcomas have not been determined...
Chemoradiation for primary invasive squamous carcinoma of the vaginaJ L Dalrymple
University of California at Davis, Medical Center, Division of Gynecologic Oncology, Sacramento, CA 95817, USA
Int J Gynecol Cancer 14:110-7. 2004..To report outcomes for patients with primary, invasive, squamous carcinoma of the vagina treated with chemoradiation...
Fertility-sparing radical abdominal trachelectomy for clear cell adenocarcinoma of the upper vagina: a case reportKellie S Matthews
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249 7333, USA
Gynecol Oncol 105:820-2. 2007..Due to a bimodal distribution, women of reproductive age are frequently affected and could benefit from radical trachelectomy to preserve fertility...
Population-based incidence of vulvar and vaginal melanoma in various races and ethnic groups with comparisons to other site-specific melanomasDan Ning Hu
Department of Pathology, New York Eye and Ear Infirmary, New York Medical College, Valhalla, New York, USA
Melanoma Res 20:153-8. 2010..The slight decrease of incidence of vulvar melanoma in dark pigmented individuals may be related to the biochemical protective effects of melanin (as an antioxidant) rather than their photo-screen effects...
Vaginal masses: magnetic resonance imaging features with pathologic correlationK M Elsayes
Department of Radiology, University of Michigan Health System, Ann Arbor, MI, USA
Acta Radiol 48:921-33. 2007..In this article, we will review pertinent vaginal anatomy, vaginal and pelvic MRI technique, and the MRI features of a variety of vaginal lesions with pathological correlation...
Medical and surgical management of reproductive neoplasia in two western lowland gorillas (Gorilla gorilla gorilla)Elizabeth M Stringer
North Carolina State University, College of Veterinary Medicine, Raleigh, NC 27606, USA
J Med Primatol 39:328-35. 2010..Reports of female reproductive tract neoplasia are infrequent in great apes...
Non-muscle invasive bladder cancer with concomitant vaginal urothelial carcinoma: a case report and review of the literatureGou Kaneko
Department of Urology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
Int J Clin Oncol 15:626-30. 2010..The pathogenesis of the vaginal UC was considered to be the primary UC or metastasis from the bladder UC. Vaginal UC is extremely rare and this is only the 15th report in the literature...
Exclusive radiotherapy for primary squamous cell carcinoma of the vaginaRenaud de Crevoisier
Department of Radiation Oncology, Institut Gustave Roussy, 39 rue Camille Desmoulins, Villejuif, France
Radiother Oncol 85:362-70. 2007..To retrospectively analyze results of external beam therapy (EBT) with brachytherapy (BT) for primary vaginal squamous cell carcinoma (PVSCC)...
Postirradiation primary vaginal angiosarcoma with widespread intra-abdominal metastasisAidan Brady
Department of Pathology, Gynaecological Oncology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
Int J Gynecol Pathol 30:514-7. 2011..All of the earlier reported cases have been localized to the pelvis without metastatic disease...
Cytological features of transitional cell metaplasia of the lower female genital tractRajmohan Murali
Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, Australia
Pathology 42:113-8. 2010..Transitional cell metaplasia (TCM) of the cervix and vaginal vault is rarely reported. We sought to describe the clinical and cytological features and cytological differential diagnosis of TCM...
Vaginal wall fibroidT D Theodoridis
1st Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, 8, Agias Theodoras Street, 546 23, Thessaloniki, Greece
Arch Gynecol Obstet 278:281-2. 2008..We report about a case of a vaginal leiomyoma in the anterior vaginal wall, preoperatively identified with sonography and CT. Surgical enucleation was performed. Surgical removal in these cases is safe and usually with minimal bleeding...
A clinicopathological study of malignant melanoma with special reference to atypical presentationSubhalakshmi Mukhopadhyay
Department of Pathology, Midnapore Medical College, West Bengal, India
Indian J Pathol Microbiol 51:485-8. 2008..The clinical presentation of the case of vaginal melanoma and the two cases of secondary melanomas, including the one with obscure primary tumor, were bewildering and hence are discussed separately...
Descriptive epidemiology of vaginal cancer incidence and survival by race, ethnicity, and age in the United StatesXiaocheng Wu
Louisiana Tumor Registry, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
Cancer 113:2873-82. 2008..It has many of the same risk factors as cervical cancer, including a strong association with persistent human papillomavirus infection. Descriptive studies of the epidemiology of vaginal cancer are scarce in the literature...
Leiomyoma appearing in the vaginal vault following hysterectomyS R Yanamandra
Birmingham Women's Hospital, Birmingham, UK
J Obstet Gynaecol 27:91-2. 2007
Entirely robotic total pelvic exenterationCatalin Vasilescu
Fundeni Institute of Digestive Disease and Liver Transplantation, Bucharest, Romania
Surg Laparosc Endosc Percutan Tech 21:e200-2. 2011..In 1948, Brunschwig first described a pelvic exenteration as treatment of advanced recurrent malignancy in the pelvis. Currently it represents the only potentially curative option for patients with recurrent endometrial cancer...
Biological effective dose evaluation in gynaecological brachytherapy: LDR and HDR treatments, dependence on radiobiological parameters, and treatment optimisationC Bianchi
Servizio di Fisica Sanitaria, Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
Radiol Med 113:1068-78. 2008....
Clinical utility of the modified segmental boost technique for treatment of the pelvis and inguinal nodesM S Moran
Yale University School of Medicine, Department of Therapeutic Radiology, Yale New Haven Hospital, 333 Cedar Street, P O Box 208040, New Haven, CT 06520 8040, USA
Int J Radiat Oncol Biol Phys 76:1026-36. 2010..We previously reported improved homogeneity with the modified segmental boost technique (MSBT) compared to that with traditional methods, using phantom models. Here we report our institutional clinical experience with MSBT...
Update of HPV-associated female genital cancers in the United States, 1999-2004Meg Watson
Epidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
J Womens Health (Larchmt) 18:1731-8. 2009..Enhancing current cancer surveillance systems, combined with special studies to collect data on in situ or precancerous lesions of these cancers, will provide important information in determining the potential impact of the HPV vaccine...
Bowenoid epidermotropic metastatic squamous cell carcinomaChull-Wan Ihm
Am J Dermatopathol 29:422; author reply 422. 2007
Diethylstilbestrol (DES)-induced clear cell adenocarcinoma of the vagina metastasizing to the brainLi Mei Lin
Department of Neurosurgery, Johns Hopkins School of Medicine, 600 North Wolfe Street, Meyer 8 161, Baltimore, MD 21287, USA
Gynecol Oncol 105:273-6. 2007..Vaginal CCA commonly metastasizes to the lungs and the supraclavicular lymph nodes; however we present a rare case of diethylstilbestrol-induced vaginal CCA with cerebral metastases...
Primary vaginal adenosarcoma with sarcomatous overgrowthMasafumi Toyoshima
Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba, Sendai 980 8574, Japan
Gynecol Oncol 95:759-61. 2004..Primary vaginal adenosarcomas are extremely rare, and typical adenosarcomas are of low malignancy. However, aggressive forms with sarcomatous overgrowth have been reported, those appear to have a poor prognosis...
Adenosarcoma in a patient with vaginal endometriosisJ Anderson
Department of Pathology, Rush Medical College, Chicago, Illinois 60612, USA
Obstet Gynecol 98:964-6. 2001..Eventually, a vaginal adenosarcoma was diagnosed. CONCLUSION: The possibility of adenosarcoma should be considered if an enlarging mass occurs at the site of extraovarian endometriosis...
Bethesda 2001 implementation and reporting rates: 2003 practices of participants in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal CytologyDiane D Davey
Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington 40526 0298, USA
Arch Pathol Lab Med 128:1224-9. 2004..The 2001 Bethesda System for the reporting of cervical cytology specimens and the use of new liquid-based and human papillomavirus testing technologies have led to changes in cervical cytology reporting practices...
Vaginal cuff recurrence of endometrial cancer treated by laparoscopic-assisted vaginal hysterectomyChristina S Chu
Division of Gynecologic Oncology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
Gynecol Oncol 88:62-5. 2003..Although studies have reported good results with equivalent rates of recurrence and survival, the need for use of intrauterine manipulators during the LAVH raises the concern for operative dissemination of tumor cells...
[Primary vaginal and uterine melanoma--a case of long term survival after local excision and vaginal brachytherapy]G Panek
Ginekol Pol 72:1501-6. 2001..In general the prognosis in women with these malignancy is poor regardless of type of surgery. Depth of infiltration seems to be the only important prognostic factor influencing the survival...
Aggressive angiomyxoma of the vagina: a case report and review of the literatureD J Papachristou
Department of Pathology, University Hospital of Ioannina, Ioannina, Greece
Eur J Gynaecol Oncol 25:519-21. 2004..Furthermore, we attempt to enlighten the possible mechanisms that govern the pathogenesis and the biological behavior of this "mysterious" neoplasm...
Research Grants
- A Molecular Signature of Early Cervical CarcinomaConcepcion Diaz Arrastia; Fiscal Year: 2007..I propose to identify a genomic and proteomic signature of cervical cancer that will predict the aggressive behavior of the tumor and function clinically to develop molecular-based treatment plans. ..
- Inflamation and the Risk of Endometrial CancerAkila Viswanathan; Fiscal Year: 2007..This proposal will ensure that she will become an established independent investigator and a leading expert in gynecologic cancer epidemiology. ..
- A Pilot Study Of Internet Recruitment and follow-up among Reproductive Age WomenELIZABETH HATCH; Fiscal Year: 2007..If successful, we envision this study to be the first of more elaborate studies that employ the internet to enroll cohort members into long-term follow-up studies. ..
- CCBAR Workshop 2006-2007STACY LINDAU; Fiscal Year: 2007....
- The Association between obesity, central adiposity and endocrine disruptorsELIZABETH HATCH; Fiscal Year: 2007..The study is limited by its cross-sectional nature. Nevertheless, it may provide important clues for future, epidemiologic studies of the effect of these environmental contaminants on the risk of obesity. ..
- Gene Polymorphisms in Relation to Cancer in Black WomenJulie Palmer; Fiscal Year: 2007..The BWHS will provide the largest source of data on gene-environment interactions in black women, and will contribute substantially to the data available on young women of any race. ..
- Lifestyle Factors and Type 2 Diabetes in Black WomenJulie Palmer; Fiscal Year: 2007..Because the follow-up and data collection are funded by another grant, the proposed large study of modifiable risk factors for type 2 diabetes can be carried out at a relatively modest cost. ..
- Breast and Prostate Cancer Data Quality and Patterns of Care StudyXiaocheng Wu; Fiscal Year: 2007..abstract_text> ..
- Progestin Actions in the Primate Breast and UterusCharles Wood; Fiscal Year: 2007..This work will have immediate public health relevance to postmenopausal women seeking the safest form of hormone therapy. ..
- Effect of Male Circumcision on Penile HPV InfectionJENNIFER SUSAN SMITH; Fiscal Year: 2010..If male circumcision is found to be effective and safe in reducing HPV infection or penile lesions in men, it could in turn reduce HPV prevalence and associated cervical neoplasia in women. ..
- An internet based prospective study of time to pregnancyElizabeth E Hatch; Fiscal Year: 2010..Identifying modifiable risk factors for infertility and miscarriage is an important public health goal, especially because the effectiveness of treatments for these conditions is relatively poor. ..
- CALCIUM CHANNEL BLOCKERS IN BREAST CANCER ETIOLOGYJanet Daling; Fiscal Year: 2001..cimetidine, anti-depressants, lipid lowering drugs) frequently used by women in this age group. ..
- HRT USE AND RISK OF LOBULAR AND DUCTAL BREAST CANCERJanet Daling; Fiscal Year: 2004..of CHRT associated with alteration in the histologic characteristics, tumor cell proliferation, or expression of steroid hormone receptors, oncogenes, and cell cycle and cell death regulator proteins of lobular and ductal breast cancers? ..
- Tamoxifen & Second Breast Cancer: Epidemiology/PathologyJanet Daling; Fiscal Year: 2004..which women have increased or decreased risks of developing CBC if they use tamoxifen? (4) Among the CBC cases, how does tamoxifen alter the expression of these tumor markers in first compared to contralateral cancers? ..
- ELECTRIC INJURY--IMAGING OF THERMAL/NON-THERMAL ASPECTSRaphael Lee; Fiscal Year: 2003..abstract_text> ..
- Biopolymer Surfactants for Sealing Electroporated MembranesRaphael Lee; Fiscal Year: 2007..Finally, we will conduct studies in parallel to determine if surfactant rescued cells manifest normal phenotype during proliferation or exhibit effects of mutations caused by unrepaired DMA. ..
