uterine prolapse

Summary

Summary: Downward displacement of the UTERUS. It is classified in various degrees: in the first degree the UTERINE CERVIX is within the vaginal orifice; in the second degree the cervix is outside the orifice; in the third degree the entire uterus is outside the orifice.

Top Publications

  1. pmc The prevalence of pelvic organ prolapse symptoms and signs and their relation with bladder and bowel disorders in a general female population
    Marijke C Ph Slieker-ten Hove
    COBRA Research Institute, Pelvic floor research, Amersfoort, The Netherlands
    Int Urogynecol J Pelvic Floor Dysfunct 20:1037-45. 2009
  2. ncbi Anterior colporrhaphy: a randomized trial of three surgical techniques
    A M Weber
    Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, Ohio, USA
    Am J Obstet Gynecol 185:1299-304; discussion 1304-6. 2001
  3. ncbi A prospective, randomised, controlled trial comparing 3 hour and 24 hour postoperative removal of bladder catheter and vaginal pack following vaginal prolapse surgery
    Karin Glavind
    Department of Gynecology and Obstetrics, Aalborg Sygehus, Aalborg, Denmark
    Acta Obstet Gynecol Scand 86:1122-5. 2007
  4. ncbi Complication and reoperation rates after apical vaginal prolapse surgical repair: a systematic review
    Gouri B Diwadkar
    Department of Ob Gyn, Cleveland Clinic, Cleveland, OH 44198, USA
    Obstet Gynecol 113:367-73. 2009
  5. ncbi Pelvic organ prolapse in the Women's Health Initiative: gravity and gravidity
    Susan L Hendrix
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Am J Obstet Gynecol 186:1160-6. 2002
  6. ncbi Long term review of laparoscopic sacrocolpopexy
    P J Higgs
    Urogynaecology Department, Royal Women s Hospital, Melbourne, Australia
    BJOG 112:1134-8. 2005
  7. ncbi Vesicovaginal fistula and mesh erosion after Perigee (transobturator polypropylene mesh anterior repair)
    Brian S Yamada
    Virginia Mason Medical Center, Seattle, Washington 98101, USA
    Urology 68:1121.e5-7. 2006
  8. ncbi Surgical management of pelvic organ prolapse in women: a short version Cochrane review
    C Maher
    Neurourol Urodyn 27:3-12. 2008
  9. ncbi Women seeking treatment for advanced pelvic organ prolapse have decreased body image and quality of life
    J Eric Jelovsek
    Division of Urogynecology and Pelvic Reconstructive Surgery, Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Obstet Gynecol 194:1455-61. 2006
  10. ncbi Laparoscopic sacrocolpopexy for severe vaginal vault prolapse: five-year outcome
    Jim W Ross
    Department of Obstetrics and Gynecology, UCLA School of Medicine, Salinas, California 93901, USA
    J Minim Invasive Gynecol 12:221-6. 2005

Research Grants

  1. A SYSTEM FOR MEASURING PELVIC MUSCLE STRENGTH IN WOMEN
    Neil Cole; Fiscal Year: 2003
  2. Epidemiology of Female Pelvic Floor Disorders
    Kristen Kjerulff; Fiscal Year: 2001
  3. Improved Surgical Treatment of Pelvic Organ Prolapse
    KEITH LIPFORD; Fiscal Year: 2009
  4. Pelvic Floor Disorders Network
    CHARLES WILLIAM NAGER; Fiscal Year: 2013
  5. Mechanisms of anterior vaginal wall support failure
    John O L Delancey; Fiscal Year: 2013
  6. URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERS
    GUNHILDE BUCHSBAUM; Fiscal Year: 2003
  7. Female Pelvic Floor Disorders and Sexual Functions
    Victoria Handa; Fiscal Year: 2007
  8. BOTULINUM TOXIN THERAPY FOR INTERSTITIAL CYSTITIS/CHRON*
    Mary FitzGerald; Fiscal Year: 2007
  9. Sensory Testing in Subjects with Interstitial Cystitis
    Mary FitzGerald; Fiscal Year: 2004
  10. A new tool to diagnose female urinary incontinence
    Catherine Bradley; Fiscal Year: 2008

Detail Information

Publications233 found, 100 shown here

  1. pmc The prevalence of pelvic organ prolapse symptoms and signs and their relation with bladder and bowel disorders in a general female population
    Marijke C Ph Slieker-ten Hove
    COBRA Research Institute, Pelvic floor research, Amersfoort, The Netherlands
    Int Urogynecol J Pelvic Floor Dysfunct 20:1037-45. 2009
    ..Our aim was to obtain normative data on the prevalence of POP and pelvic floor dysfunction (PFD) symptoms and signs and to identify associations...
  2. ncbi Anterior colporrhaphy: a randomized trial of three surgical techniques
    A M Weber
    Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, Ohio, USA
    Am J Obstet Gynecol 185:1299-304; discussion 1304-6. 2001
    ..The addition of polyglactin 910 mesh did not improve the cure rate compared with standard anterior colporrhaphy...
  3. ncbi A prospective, randomised, controlled trial comparing 3 hour and 24 hour postoperative removal of bladder catheter and vaginal pack following vaginal prolapse surgery
    Karin Glavind
    Department of Gynecology and Obstetrics, Aalborg Sygehus, Aalborg, Denmark
    Acta Obstet Gynecol Scand 86:1122-5. 2007
    ....
  4. ncbi Complication and reoperation rates after apical vaginal prolapse surgical repair: a systematic review
    Gouri B Diwadkar
    Department of Ob Gyn, Cleveland Clinic, Cleveland, OH 44198, USA
    Obstet Gynecol 113:367-73. 2009
    ..To compare postoperative complication and reoperation rates for surgical procedures correcting apical vaginal prolapse...
  5. ncbi Pelvic organ prolapse in the Women's Health Initiative: gravity and gravidity
    Susan L Hendrix
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Am J Obstet Gynecol 186:1160-6. 2002
    ..The purpose of this study was to describe the prevalence of and correlates for pelvic organ prolapse...
  6. ncbi Long term review of laparoscopic sacrocolpopexy
    P J Higgs
    Urogynaecology Department, Royal Women s Hospital, Melbourne, Australia
    BJOG 112:1134-8. 2005
    ..Assessment of long term outcome following laparoscopic sacrocolpopexy...
  7. ncbi Vesicovaginal fistula and mesh erosion after Perigee (transobturator polypropylene mesh anterior repair)
    Brian S Yamada
    Virginia Mason Medical Center, Seattle, Washington 98101, USA
    Urology 68:1121.e5-7. 2006
    ..This is a serious complication associated with this technique. Treatment required an open vesicovaginal fistula repair with excision of the exposed and nearby surrounding mesh...
  8. ncbi Surgical management of pelvic organ prolapse in women: a short version Cochrane review
    C Maher
    Neurourol Urodyn 27:3-12. 2008
    ..Pelvic organ prolapse may occur in up to 50% of parous women. A variety of urinary, bowel and sexual symptoms may be associated with prolapse...
  9. ncbi Women seeking treatment for advanced pelvic organ prolapse have decreased body image and quality of life
    J Eric Jelovsek
    Division of Urogynecology and Pelvic Reconstructive Surgery, Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Obstet Gynecol 194:1455-61. 2006
    ..To date, there are no data on body image in patients with advanced pelvic organ prolapse. Our objective was to compare body image and quality of life in women with advanced pelvic organ prolapse with normal controls...
  10. ncbi Laparoscopic sacrocolpopexy for severe vaginal vault prolapse: five-year outcome
    Jim W Ross
    Department of Obstetrics and Gynecology, UCLA School of Medicine, Salinas, California 93901, USA
    J Minim Invasive Gynecol 12:221-6. 2005
    ..To assess the efficacy of the laparoscopic sacrocolpopexy in the treatment of severe vaginal prolapse...
  11. ncbi Sexual function in women with urinary incontinence and pelvic organ prolapse
    Matthew D Barber
    Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Obstet Gynecol 99:281-9. 2002
    ..To compare sexual function in women with urinary incontinence and pelvic organ prolapse and to determine the effects of therapy on sexual function...
  12. ncbi Barriers to seeking treatment for women with persistent or recurrent symptoms in urogynaecology
    M Basu
    Department of Obstetrics and Gynaecology, Medway Maritime Hospital, Gillingham, Kent, UK
    BJOG 116:726-30. 2009
    ..Dominant themes were beliefs about ageing, attitudes towards incontinence, health professionals and treatment and access to services. These factors may be important when counselling women postoperatively...
  13. ncbi The current status of laparoscopic sacrocolpopexy: a review
    Anjali M Ganatra
    Department of Urology, Institut Montsouris, Universite Paris Descartes, Paris, France
    Eur Urol 55:1089-103. 2009
    ..Vaginal prolapse repairs, however, are often faster and offer patients a shorter recovery time. Laparoscopic sacrocolpopexy (LSC) aims to bridge this gap and to provide the outcomes of ASC with decreased morbidity...
  14. ncbi Efficacy and safety of transvaginal mesh kits in the treatment of prolapse of the vaginal apex: a systematic review
    B Feiner
    Division of Urogynaecology and Reconstructive Pelvic Surgery, Royal Women s, Mater and Wesley Hospitals, Brisbane, Queensland, Australia
    BJOG 116:15-24. 2009
    ..Vaginal mesh kits are being used to surgically treat apical vaginal prolapse; however, their safety and efficacy are currently unknown...
  15. ncbi Functional results and quality-of-life after bilateral sacrospinous ligament fixation for genital prolapse
    Emmanuel David-Montefiore
    Service de Gynecologie, obstétrique et médecine de la reproduction, Hopital Tenon, Université Saint Antoine Paris IV, Assistance Publique des Hopitaux de Paris, 4 rue de la Chine, 75020 Paris Cedex 20, France
    Eur J Obstet Gynecol Reprod Biol 132:209-13. 2007
    ..To evaluate intra- and post-operative complications, anatomical results, quality-of-life and sexuality after bilateral sacrospinous ligament fixation (SSLF)...
  16. ncbi Risk factors for uterine prolapse in Nepal
    Barbara Bodner-Adler
    Department of Gynecology, Dr Iwamura Memorial Hospital and Research Center, Sallaghari, Bhaktapur District, Nepal
    Int Urogynecol J Pelvic Floor Dysfunct 18:1343-6. 2007
    b>Uterine prolapse is a significant public health problem in Nepal. The aim of this study was to determine the prevalence of uterine prolapse and to define possible risk factors for this disease in the Kathmandu Valley of Nepal...
  17. ncbi A prospective study of laparoscopic sacrocolpopexy for the management of pelvic organ prolapse
    C E North
    Department of Urogynaecology, St Mary s Hospital, Whitworth Park, Manchester, UK
    BJOG 116:1251-7. 2009
    ..Assessment of the 2-year outcome of laparoscopic sacrocolpopexy...
  18. ncbi Abdominal sacrocolpopexy--standardized surgical technique, perioperative management and outcome in women with posthysterectomy vaginal vault prolapse
    Markus Huebner
    Department of Urogynecology, German Pelvic Floor Center, ST Hedwig Hospitals, Berlin, Germany
    Gynakol Geburtshilfliche Rundsch 49:308-14. 2009
    ..To provide a detailed description of abdominal sacrocolpopexy and to present a retrospective evaluation of the outcomes...
  19. ncbi Repair of the anterior vaginal compartment
    Sarah Hamilton Boyles
    Oregon Health and Science University, Portland, Oregon, USA
    Clin Obstet Gynecol 48:682-90. 2005
  20. ncbi De novo urinary stress incontinence after laparoscopic sacral colpopexy
    Vincent Misrai
    Department of Urology, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris AP HP, Faculte de Medecine Pierre et Marie Curie, University Paris VI, France
    BJU Int 101:594-7. 2008
    ..To analyse the incidence and the risk of developing de novo stress urinary incontinence (SUI) after laparoscopic sacral colpopexy (LSCP)...
  21. ncbi [Prolapse in the young woman: study of risk factors]
    B Deval
    Service de Gynecologie Obstetrique, Université Bichat Beaujon, Hopital Beaujon, 100, Bd du Général Leclerc, 92110 Clichy, France
    Gynecol Obstet Fertil 30:673-6. 2002
    ..To determine the risk factors for genital prolapse in a group of 37 young women less than 45 years old...
  22. ncbi Expression of matrix metalloproteinase-2 and tissue inhibitors of metalloproteinase-1 (TIMP-1, TIMP-2 and TIMP-3) in women with uterine prolapse but without urinary incontinence
    Ching Chung Liang
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Taiwan, ROC
    Eur J Obstet Gynecol Reprod Biol 153:94-8. 2010
    ..metalloproteinase-2 (MMP-2) and its inhibitors, tissue inhibitor of metalloproteinase-1, -2 and -3 (TIMP-1, TIMP-2 and TIMP-3), in the pelvic support and nonsupport tissue of women with uterine prolapse but without urinary incontinence.
  23. ncbi Collagen metabolism in the uterosacral ligaments and vaginal skin of women with uterine prolapse
    Christian H Phillips
    Faculty of Medicine Maternal, Fetal and Neonatal Physiology Group, Department of Gynecology, Princess Anne Hospital, Southampton, Hampshire, UK
    BJOG 113:39-46. 2006
    To compare tissue markers of collagen metabolism in the uterosacral ligaments with those in vaginal tissue in women with uterine prolapse.
  24. ncbi Differential expression of fibulins in the uterosacral ligaments of women with uterine prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology, Jackson Memorial Hospital, University of Miami, Miami, FL 33010, USA
    Arch Gynecol Obstet 282:389-94. 2010
    To compare fibulin-3 (FIB-3) and fibulin-5 (FIB-5) expressions in uterosacral ligaments (USL) of women with and without uterine prolapse.
  25. ncbi Anterior vaginal wall prolapse: a randomized controlled trial of SIS graft versus traditional colporrhaphy
    Paulo Cezar Feldner
    Section of Urogynecology and Pelvic Surgery, Department of Gynecology, Universidade Federal de Sao Paulo, Rua dos Otonis, 601 Vila Clementino, 04025 001, Sao Paulo, SP, Brazil
    Int Urogynecol J 21:1057-63. 2010
    ..This study seeks to compare the small intestine submucosa (SIS) graft with traditional colporrhaphy (TC) for surgical treatment of anterior vaginal prolapse...
  26. ncbi Abdominal sacral colpopexy with prolene mesh
    M Schettini
    Department of Urology, Cristo Re Hospital, Rome, Italy
    Int Urogynecol J Pelvic Floor Dysfunct 10:295-9. 1999
    ..colposacropexy on 15 patients for simple vaginal vault prolapse (in 7 cases after hysterectomy) and for total uterine prolapse in 8 cases. In these cases a simple abdominal hysterectomy was performed...
  27. ncbi Incidence rate and risk factors for vaginal vault prolapse repair after hysterectomy
    Patrick Dällenbach
    Department of Gynecology and Obstetrics, Division of Gynecology, Perineology Unit, University Hospitals of Geneva, 30 Boulevard de la Cluse, 1211, Geneva, Switzerland
    Int Urogynecol J Pelvic Floor Dysfunct 19:1623-9. 2008
    ..9; 95% CI 0.5-1.8).Vaginal vault prolapse repair after hysterectomy is an infrequent event and is due to preexisting weakness of pelvic tissues...
  28. ncbi Vaginal paravaginal repair: one-year outcomes
    S B Young
    Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Massachusetts, UMass Memorial Health Care, Worcester, 01655, USA
    Am J Obstet Gynecol 185:1360-6; discussion 1366-7. 2001
    ..CONCLUSIONS: The vaginal approach to the correction of paravaginal defect cystocele is highly effective in our population at a mean of 11 months after the operation. Frequent complications do occur but are largely manageable...
  29. pmc Uterine prolapse
    Anjum Doshani
    Urogynaecology Department, Women s, Perinatal and Sexual Health Directorate, Leicester General Hospital, University Hospitals of Leicester NHS Trust, Leicester LE5 4PW
    BMJ 335:819-23. 2007
  30. pmc Incidence of pelvic floor repair after hysterectomy: A population-based cohort study
    Roberta E Blandon
    Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Am J Obstet Gynecol 197:664.e1-7. 2007
    ..The objective of the study was to assess the incidence of and risk factors for pelvic floor repair (PFR) procedures after hysterectomy...
  31. pmc One-year follow-up after sacrospinous hysteropexy and vaginal hysterectomy for uterine descent: a randomized study
    Viviane Dietz
    Department of Obstetrics and Gynecology, Catharina Medical Center, Michelangelolaan 2, 5623, Eindhoven, The Netherlands
    Int Urogynecol J 21:209-16. 2010
    ..In a retrospective study, the sacrospinous hysteropexy was associated with a shorter recovery time compared to a vaginal hysterectomy with no differences in anatomical outcomes. No randomized trials are performed...
  32. ncbi Uterine preservation or hysterectomy at sacrospinous colpopexy for uterovaginal prolapse?
    C F Maher
    Royal Women s and Mercy Hospital, Melbourne, Australia
    Int Urogynecol J Pelvic Floor Dysfunct 12:381-4; discussion 384-5. 2001
    ..a sacrospinous hysteropexy and 36 who had a vaginal hysterectomy and sacrospinous fixation for symptomatic uterine prolapse. All women underwent independent review and examination, with a mean follow-up of 36 months in the ..
  33. ncbi Posterior intravaginal slingplasty with preservation of the uterus: a modified surgical technique in a young myelomeningocele patient
    Jasper Verguts
    Bekkenbodemcentrum, University Hospital Gasthuisberg, Leuven, Belgium
    Gynecol Obstet Invest 63:203-4. 2007
    We report a case of uterine prolapse in a young woman, treated by posterior intravaginal slingplasty with preservation of the uterus as a feasible and safe surgical procedure...
  34. ncbi Functional and anatomical outcome of anterior and posterior vaginal prolapse repair with prolene mesh
    Rodolfo Milani
    Divisione di Ginecologia Chirurgica, Ospedale Bassini, University of Milan Bicocca, Italy
    BJOG 112:107-11. 2005
    ..To evaluate the effects of prolene mesh on urinary, bowel and sexual function in prolapse surgery...
  35. ncbi Impact of vaginal surgery on sexuality and quality of life in women with urinary incontinence or genital descensus
    Lotti Helström
    Department of Women and Child Health, Karolinska Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 84:79-84. 2005
    ..To study the effect of vaginal surgery for urinary incontinence and genital descensus on sexual function and quality of life...
  36. ncbi Pelvic Organ Support Study (POSST) and bowel symptoms: straining at stool is associated with perineal and anterior vaginal descent in a general gynecologic population
    Margie A Kahn
    Division of Benign Gynecology, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston 77555 0587, USA
    Am J Obstet Gynecol 192:1516-22. 2005
    ..The purpose of this study was to evaluate the association of constipation symptoms and anal incontinence with vaginal wall and pelvic organ descent in a general gynecologic population...
  37. ncbi Lifetime risk of surgical management for pelvic organ prolapse or urinary incontinence
    M F Fialkow
    Department of Obstetrics and Gynecology, Univ of Washington School of Medicine, Box 356460, Seattle, WA 98195, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:437-40. 2008
    ..POP and UI appear to be common problems, undoubtedly affecting an even larger proportion of the women than suggested by this high cumulative incidence of surgery...
  38. ncbi Clinical relevance of urodynamic investigation tests prior to surgical correction of genital prolapse: a literature review
    Jan Paul W R Roovers
    Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam, Room H4 205, P O Box 22700, 1105 DE, Amsterdam, The Netherlands
    Int Urogynecol J Pelvic Floor Dysfunct 18:455-60. 2007
    ..This review presents a literature overview of what has been proven about the diagnostic and therapeutic value of urodynamic investigations in patients undergoing prolapse surgery...
  39. ncbi A randomised controlled trial comparing abdominal and vaginal prolapse surgery: effects on urogenital function
    Jan Paul W R Roovers
    Department of Obstetrics and Gynaecology, University Medical Center, Utrecht, The Netherlands
    BJOG 111:50-6. 2004
    ..To compare the effects of vaginal hysterectomy (combined with anterior and/or posterior colporraphy) and abdominal sacro-colpopexy (with preservation of the uterus) on urogenital function...
  40. ncbi Obstetric risk factors for symptomatic prolapse: a population-based approach
    Gunilla Tegerstedt
    Department of Obstetrics and Gynaecology, Stockholm Soder Hospital, Stockholm, Sweden
    Am J Obstet Gynecol 194:75-81. 2006
    ..The purpose of this study was to identify obstetric risk factors for symptomatic prolapse...
  41. ncbi Risk factors for pelvic organ prolapse repair after hysterectomy
    Patrick Dällenbach
    Department of Gynecology and Obstetrics, Division of Gynecology, Urogynecology Unit, Geneva University Hospitals, Geneva, Switzerland
    Obstet Gynecol 110:625-32. 2007
    ..To estimate the incidence and identify the risk factors for pelvic organ prolapse repair after hysterectomy...
  42. ncbi The relationship of vaginal prolapse severity to symptoms and quality of life
    G Alessandro Digesu
    Academic Department of Obstetrics and Gynaecology, Urogynaecology Unit, Imperial College, St Mary s Hospital, London, UK
    BJOG 112:971-6. 2005
    ..To assess the relationship and location of vaginal prolapse severity to symptoms and quality of life...
  43. ncbi Recurrent pelvic organ prolapse in a woman with bladder exstrophy: a case report of surgical management and review of the literature
    Tristi W Muir
    The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Int Urogynecol J Pelvic Floor Dysfunct 15:436-8. 2004
    ..A case of recurrent pelvic organ prolapse successfully managed with a sacral colpopexy and a review of the literature are presented...
  44. ncbi Racial characteristics of women undergoing surgery for pelvic organ prolapse in the United States
    Aparna D Shah
    Division of Urogynecology, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Obstet Gynecol 197:70.e1-8. 2007
    ..This study was undertaken to compare the prevalence, demographics, and complications of pelvic organ prolapse surgery across races in the United States...
  45. ncbi National survey on the management of prolapse in the UK
    Swati Jha
    Urogynaecology Department, Birmingham Women s Hospital, Metchley Park Road, Birmingham, United Kingdom
    Neurourol Urodyn 26:325-31; discussion 332. 2007
    ....
  46. ncbi Laparoscopic uterine sling suspension: a new technique of uterine suspension in women desiring surgical management of uterine prolapse with uterine conservation
    A Cutner
    Department of Obstetrics and Gynaecology, University College Hospital, London, UK alfred cutner uclh nhs uk
    BJOG 114:1159-62. 2007
    The surgical management of uterine prolapse in women who wish to retain their uterus remains a challenge. Several techniques have been reported using open abdominal, laparoscopic and vaginal approaches...
  47. ncbi Heterogeneity in anatomic outcome of sacrospinous ligament fixation for prolapse: a systematic review
    Daniel M Morgan
    Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Obstet Gynecol 109:1424-33. 2007
    ..To explore why failure rates vary so much between published reports of sacrospinous ligament fixation to correct pelvic organ prolapse and what the potential sources of heterogeneity may be...
  48. ncbi Long-term results of abdominal sacrocolpopexy
    Wesley S Hilger
    Department of Obstetrics and Gynecology, LDS Hospital, University of Utah Medical Center, Salt Lake City, UT, USA
    Am J Obstet Gynecol 189:1606-10; discussion 1610-1. 2003
    ..Our purpose was to determine the long-term results after abdominal sacrocolpopexy...
  49. ncbi Abdominal sacrocolpopexy and anatomy and function of the posterior compartment
    K Baessler
    Kantonsspital Luzern, Luzern, Switzerland
    Obstet Gynecol 97:678-84. 2001
    ..Twenty-eight percent of women described altered defecation with stool stopping higher in the rectosigmoid colon ("high outlet constipation"), which might have been caused by denervation during rectal mobilization...
  50. ncbi The natural history of pelvic organ support in pregnancy
    A L O'Boyle
    Madigan Army Medical Center, Department of Obstetrics and Gynecology, Division of Urogynecology, 9040A Reid Street Tacoma, WA 98431, USA
    Int Urogynecol J Pelvic Floor Dysfunct 14:46-9; discussion 49. 2003
    ..These findings probably represent normal physiologic changes of the pelvic floor during pregnancy, but suggest that significant changes may be objectively demonstrated prior to delivery...
  51. ncbi Efficacy and safety of using mesh or grafts in surgery for anterior and/or posterior vaginal wall prolapse: systematic review and meta-analysis
    X Jia
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    BJOG 115:1350-61. 2008
    ..The efficacy and safety of mesh/graft in surgery for anterior or posterior pelvic organ prolapse is uncertain...
  52. pmc Is there a pelvic organ prolapse threshold that predicts pelvic floor symptoms?
    Robert E Gutman
    Departments of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 199:683.e1-7. 2008
    ..The objective of this study was to determine the minimum threshold level at which maximum anatomic prolapse predicts bothersome pelvic floor symptoms...
  53. ncbi Vaginal descent and pelvic floor symptoms in postmenopausal women: a longitudinal study
    Catherine S Bradley
    Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    Obstet Gynecol 111:1148-53. 2008
    ..To determine whether vaginal descent changes are associated with pelvic floor symptoms in postmenopausal women...
  54. pmc Functional outcome after sacrospinous hysteropexy for uterine descensus
    Viviane Dietz
    Department of Perinatology and Gynecology, University Medical Center Utrecht, Room F05 126, Heidelberglaan 100, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Int Urogynecol J Pelvic Floor Dysfunct 19:747-52. 2008
    ..Scores on all domains of urogenital symptoms and defecatory symptoms, except for the pain and fecal incontinence domain, improved significantly. Also, quality of life improved on all domains. No major complications were encountered...
  55. ncbi Longterm followup of posthysterectomy vaginal vault prolapse abdominal repair: a report of 85 cases
    Jean Pierre Lefranc
    Department of Gynecologic Surgery, Salpêtrière University Hospital, Assistance Publique Hĵpitaux de Paris, France
    J Am Coll Surg 195:352-8. 2002
    ..The aim of this study was to review the cases of 85 consecutive patients treated by this technique since 1978 by the same surgical team using the same procedure. Our surgical procedure will be explained...
  56. ncbi Prevalence of urinary and fecal incontinence and symptoms of genital prolapse in women
    Uustal Fornell Eva
    Department of Molecular and Clinical Medicine, Division of Obstetrics and Gynecology, University Hospital, Linkoping, Sweden
    Acta Obstet Gynecol Scand 82:280-6. 2003
    ..This epidemiological study describes a general population of women aged 40 and 60 years with regard to the prevalence and frequency of urinary and fecal incontinence and the prevalence of genital prolapse symptoms...
  57. ncbi Pelvic organ prolapse in older women: prevalence and risk factors
    Ingrid Nygaard
    University of Iowa Carver College of Medicine, Department of Obstetrics and Gynecology, Iowa City, Iowa 52242, USA
    Obstet Gynecol 104:489-97. 2004
    ..We sought to estimate the prevalence of pelvic organ prolapse in older women using the Pelvic Organ Prolapse Quantification examination and to identify factors associated with prolapse...
  58. ncbi Fast track vaginal surgery
    Marianne Ottesen
    Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark
    Acta Obstet Gynecol Scand 81:138-46. 2002
    ..Our aim was to describe the need for postoperative hospitalization after vaginal surgery for utero-vaginal prolapse with well-defined charts for postoperative care...
  59. ncbi Prediction of findings at defecography in patients with genital prolapse
    Jan Paul W R Roovers
    Department of Obstetrics and Gynecology, University Medical Center, Utrecht, The Netherlands
    BJOG 112:1547-53. 2005
    ..This study investigated whether discrimination of high and low probability of abnormal defecography is possible based on the quantified findings from patient history, pelvic examination and a validated questionnaire...
  60. ncbi Uterus preservation in surgical correction of urogenital prolapse
    Elisabetta Costantini
    Department of Urology, University of Perugia, Via Brunamonti 51, 06100 Perugia, Italy
    Eur Urol 48:642-9. 2005
    ..This study aimed to evaluate the efficacy of colposacropexy with uterine preservation as therapy for uterovaginal prolapse. Surgical techniques, efficacy and overall results are described...
  61. ncbi Risk factors for prolapse recurrence after vaginal repair
    James L Whiteside
    Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am J Obstet Gynecol 191:1533-8. 2004
    ..The purpose of this study was to determine factors that are associated with recurrent prolapse...
  62. ncbi Long-term success of abdominal sacral colpopexy using synthetic mesh
    Patrick J Culligan
    Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology, and Women s Health, University of Louisville Health Sciences Center, KY, USA
    Am J Obstet Gynecol 187:1473-80; discussion 1481-2. 2002
    ..The aim was to determine the minimum meaningful study period required for prospective trials involving sacral colpopexy...
  63. ncbi Uterine prolapse in pregnancy
    Lorenzo Guariglia
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Gynecol Obstet Invest 60:192-4. 2005
    We present a case of a patient developing uterine prolapse during pregnancy. The cervix reached the introitus at 10 weeks gestation and subsequently protruted progressively as the pregnancy advanced...
  64. ncbi Pelvic Organ Support Study (POSST): the distribution, clinical definition, and epidemiologic condition of pelvic organ support defects
    Steven Swift
    Department of Obstetrics and Gynecology, Divison of Benign Gynecology, Medical University of South Carolina, Charleston, SC, USA
    Am J Obstet Gynecol 192:795-806. 2005
    ..The purpose of this study was to describe the distribution of pelvic organ support in a gynecologic clinic population to define the clinical disease state of pelvic organ prolapse and to analyze its epidemiologic condition...
  65. ncbi Prevalence of severe pelvic organ prolapse in relation to job description and socioeconomic status: a multicenter cross-sectional study
    Patrick J Woodman
    Department of Obstetrics and Gynecology, Division of Urogynecology and Pelvic Reconstructive Surgery, Madigan Army Medical Center, Tacoma, WA, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:340-5. 2006
    ..001). Laborers/factory worker jobs and an annual household income of Dollars 10,000 or less are associated with severe pelvic organ prolapse...
  66. ncbi Mesh erosion after abdominal sacrocolpopexy
    N Kohli
    Division of Urogynecology and Reconstructive Pelvic Surgery, Good Samaritan Hospital, University of Cincinnati School of Medicine, Ohio 45220, USA
    Obstet Gynecol 92:999-1004. 1998
    ..To report our experience with erosion of permanent suture or mesh material after abdominal sacrocolpopexy...
  67. ncbi Long-term results of the Burch procedure combined with abdominal sacrocolpopexy for treatment of vault prolapse
    M Cosson
    Centre Hospitalier de Roubaix, Pavillon Paul Gelle, 91, avenue Julien Lagache, 59100 Roubaix, France
    Int Urogynecol J Pelvic Floor Dysfunct 14:104-7. 2003
    ..At a mean follow up of 7 years, the Burch procedure combined with abdominal sacrocolpopexy appears to be less effective than previously published long-term results for the Burch procedure alone...
  68. ncbi The use of synthetic mesh in pelvic reconstructive surgery
    Beri Ridgeway
    Department of Gynecology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin Obstet Gynecol 51:136-52. 2008
    ..Procedural kits for vaginal placement of synthetic materials are becoming popular, though long-term outcome and safety data are lacking...
  69. ncbi Procedures for pelvic organ prolapse in the United States, 1979-1997
    Sarah Hamilton Boyles
    Department of Obstetrics and Gynecology, Ohio State University, Columbus, OH, USA
    Am J Obstet Gynecol 188:108-15. 2003
    ..The objective of our study was to describe national rates of surgery for pelvic organ prolapse...
  70. ncbi Uterine preservation during surgery for uterovaginal prolapse: a review
    Aparna Diwan
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Int Urogynecol J Pelvic Floor Dysfunct 15:286-92. 2004
    ..The current literature suggests that uterine preservation during surgery for uterovaginal prolapse may be an option in appropriately selected women who desire it; prospective, randomized trials are needed to corroborate this...
  71. ncbi Uterine prolapse complicating pregnancy
    George Daskalakis
    Department of Obstetrics and Gynecology, University of Athens, Alexandra Hospital, Athens, Greece
    Arch Gynecol Obstet 276:391-2. 2007
    BACKGROUND: Uterine prolapse is extremely rare during pregnancy. However in some cases significant complications may develop. We report a case of uterine prolapse which developed during pregnancy...
  72. ncbi Short forms of two condition-specific quality-of-life questionnaires for women with pelvic floor disorders (PFDI-20 and PFIQ-7)
    M D Barber
    Department of Obstetrics and Gynecology at the Cleveland Clinic Foundation, OH 44195, USA
    Am J Obstet Gynecol 193:103-13. 2005
    ....
  73. ncbi Sexual health in women with pelvic floor disorders: measuring the sexual activity and function with questionnaires--a summary
    Montserrat Espuna Pons
    Department of Obstetrics and Gynecology, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona, 08036, Spain
    Int Urogynecol J Pelvic Floor Dysfunct 20:S65-71. 2009
    ..There is a need for a validated sexual function measure that evaluates not only the impact of pelvic floor dysfunction on sexual function but also the impact on sexual activity...
  74. ncbi How long should urinary bladder catheterisation be continued after vaginal prolapse surgery? A randomised controlled trial comparing short term versus long term catheterisation after vaginal prolapse surgery
    R A Hakvoort
    Department of Obstetrics and Gynaecology, Spaarne Hospital, Haarlem, The Netherlands
    BJOG 111:828-30. 2004
    ..To determine whether prolonged urinary bladder catheterisation after vaginal prolapse surgery is advantageous...
  75. ncbi Can a ring pessary have a lasting effect to reverse uterine prolapse even after its removal?
    Shigeki Matsubara
    Department of Obstetrics and Gynecology of Jichi Medical University, 3311 1 Yakushiji Shimotsuke, Tochigi 329 0498, Japan
    J Obstet Gynaecol Res 36:459-61. 2010
    A vaginal ring pessary for uterine prolapse has been considered only to reposition the uterus during fitting and is thus palliative. A ring pessary was fitted in a 71-year-old woman with uterine prolapse to reposition the uterus...
  76. pmc Risk factors for mesh/suture erosion following sacral colpopexy
    Geoffrey W Cundiff
    Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada
    Am J Obstet Gynecol 199:688.e1-5. 2008
    ..The purpose of this study was to identify risks for mesh/suture erosions following abdominal sacral colpopexy (ASC)...
  77. ncbi Lipogranuloma of the cervix in a postmenopausal patient with a uterine prolapse
    Metin Akbulut
    Arch Gynecol Obstet 277:277-9. 2008
    ..Lipogranuloma of the female genitalia is a rather uncommon condition. The lesion is histopathologically characterized by fat vacuoles with foreign body type giant cells and scattered lymphocytes...
  78. ncbi Transvaginal repair of genital prolapse: preliminary results of a new tension-free vaginal mesh (Prolift technique)--a case series multicentric study
    B Fatton
    Department of Obstetrics and Gynecology, Hotel Dieu, University Hospital, Clermont Ferrand, France
    Int Urogynecol J Pelvic Floor Dysfunct 18:743-52. 2007
    ..Anatomical and functional results must be assessed with a long-term follow-up to confirm the effectiveness and safety of the procedure...
  79. pmc The role of preoperative urodynamic testing in stress-continent women undergoing sacrocolpopexy: the Colpopexy and Urinary Reduction Efforts (CARE) randomized surgical trial
    Anthony G Visco
    Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Duke University Medical Center, P O Box 3192, Durham, NC 27710, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:607-14. 2008
    ..Future research is warranted in this patient population to evaluate other treatment options to refine predictions and further reduce the risk of postoperative stress incontinence...
  80. ncbi Myiasis in the uterine cavity of an elderly woman with a complete uterine prolapse
    P V Lopes-Costa
    Department of Gynecology, Federal University of Piaui, Teresina, Piaui, Brazil
    Trans R Soc Trop Med Hyg 102:1058-60. 2008
    ..This case describes an extremely rare situation, and emphasizes the need for good hygiene and surgical correction in patients with a genital prolapse...
  81. ncbi Vaginal paravaginal repair with porcine dermal reinforcement: correction of advanced anterior vaginal prolapse
    Amanda J Simsiman
    Department of Reproductive Medicine, University of California, San Diego, CA, USA
    Am J Obstet Gynecol 195:1832-6. 2006
    ..The objective of the study was to determine the efficacy of the vaginal paravaginal repair using porcine dermal graft reinforcement for the correction of advanced anterior vaginal prolapse...
  82. ncbi Posthysterectomy vault prolapse
    J W Barrington
    Torbay Hospital, Torquay, Devon, UK
    Int Urogynecol J Pelvic Floor Dysfunct 11:241-5. 2000
    ....
  83. ncbi Mesh erosion in abdominal sacral colpopexy with and without concomitant hysterectomy
    Jennifer M Wu
    Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA
    Am J Obstet Gynecol 194:1418-22. 2006
    ..The purpose of this study was to examine risk factors for mesh erosion, including concomitant hysterectomy, in abdominal sacral colpopexies...
  84. ncbi Laparoscopic uterosacral ligament uterine suspension compared with vaginal hysterectomy with vaginal vault suspension for uterovaginal prolapse
    Aparna Diwan
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:79-83. 2006
    ..No LUSUS group patient underwent reoperation for recurrent apical prolapse as compared to three TVH patients. LUSUS is an effective treatment for appropriately selected women with uterovaginal prolapse who desire uterine preservation...
  85. ncbi Why pelvic floor surgeons should utilize ultrasound imaging
    H P Dietz
    Ultrasound Obstet Gynecol 28:629-34. 2006
  86. ncbi Histological and immunohistochemical evaluation of postmenopausal endometrium after 3 weeks of treatment with tibolone, estrogen only, or estrogen plus progestagen
    Anet H A Klaassens
    Department of Obstetrics and Gynecology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Fertil Steril 86:352-61. 2006
    ..To evaluate histological and immunohistochemical parameters of short-term (21 days) tibolone, estrogen-only, and estrogen+progestagen treatment in the human postmenopausal endometrium...
  87. ncbi Is urethral mobility really being assessed by the pelvic organ prolapse quantification (POP-Q) system?
    Stephanie L Cogan
    Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Obstet Gynecol 99:473-6. 2002
    ..To estimate the relationship between Q-tip measurement of urethral hypermobility and visual assessment of the urethrovesical junction as assessed by points Aa and Ba of the pelvic organ prolapse quantification (POP-Q) system...
  88. ncbi A randomized comparison of post-operative pain, quality of life, and physical performance during the first 6 weeks after abdominal or vaginal surgical correction of descensus uteri
    J P W R Roovers
    Department of Obstetrics and Gynecology, University Medical Center Utrecht, The Netherlands
    Neurourol Urodyn 24:334-40. 2005
    ..We performed a randomized trial to compare the effects of both procedures on pain, quality of life and physical performance during the first six weeks after surgery...
  89. ncbi Correlation of symptoms with location and severity of pelvic organ prolapse
    R M Ellerkmann
    Department of Gynecology and Obstetrics, Johns Hopkins Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 185:1332-7; discussion 1337-8. 2001
    ..Increasing severity of pelvic organ prolapse is weakly to moderately associated with several specific symptoms that are related to urinary incontinence and voiding, defecatory, and sexual dysfunction...
  90. ncbi Pelvic organ prolapse: demographics and future growth prospects
    Harold P Drutz
    Section of Urogynecology, Division of Urogynecology, Department of Obstetrics and Gynecology, University of Toronto, Toronto, Canada
    Int Urogynecol J Pelvic Floor Dysfunct 17:S6-9. 2006
    ..The role of adjuvant materials in performing reconstructive pelvic surgery may improve success rates, but evidence based medicine and randomized controlled trials are currently lacking...
  91. ncbi Classification and evaluation of prolapse
    Lone Mouritsen
    Department of Gynecology and Obstetrics, Glostrup Hospital, University of Copenhagen, 2600 Glostrup, Denmark
    Best Pract Res Clin Obstet Gynaecol 19:895-911. 2005
    ..We should work on a common classification system and agreement in which symptoms should be recorded as related to prolapse and expected to improve by prolapse surgery...
  92. ncbi The demographics of pelvic floor disorders: current observations and future projections
    K M Luber
    Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, Southern California Permanenete Medical Group, San Diego, USA
    Am J Obstet Gynecol 184:1496-501; discussion 1501-3. 2001
    ..Our aim was to assess current demand for care of pelvic floor disorders and create projections for future demand for care. We also sought to better understand the characteristics of women seeking care...
  93. ncbi The ability of history and a negative cough stress test to detect occult stress incontinence in patients undergoing surgical repair of advanced pelvic organ prolapse
    Steven Kleeman
    Department of Obstetrics and Gynecology Division of Urogynecology and Pelvic Reconstructive Surgery, Good Samaritan Hospital, Cincinnati, OH, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:27-9. 2006
    ..Further work-up would not be cost effective...
  94. ncbi Sacrohysteropexy with synthetic mesh for the management of uterovaginal prolapse
    E Leron
    Department of Obstetrics and Gynaecology, Soroka Medical Centre, Ben-Gurion University of the Negev, Faculty of Health Sciences, Beer-Sheva, Israel
    BJOG 108:629-33. 2001
    ..MAIN OUTCOME MEASURES: Subjective and objective cure of uterine prolapse and operative and post-operative complications. RESULTS: The mean age of the women was 38 years (range 27-60)...
  95. ncbi Patient-centered surgical outcomes: the impact of goal achievement and urge incontinence on patient satisfaction one year after surgery
    Sangeeta T Mahajan
    Division of Female Pelvic Medicine and Reconstructive Surgery, Loyola University Medical Center, Maywood, IL, USA
    Am J Obstet Gynecol 194:722-8. 2006
    ..The purpose of this study was to assess factors that influence patient satisfaction 1 year after pelvic reconstructive surgery...
  96. ncbi Evaluation of Aa point and cotton-tipped swab test as predictors of urodynamic stress incontinence
    Karen Tapp
    Division of Urogynecology Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7570, USA
    Obstet Gynecol 105:115-9. 2005
    ..To compare the predictive abilities of the Aa point of the pelvic organ prolapse quantification examination and the cotton-tipped swab test straining angle to diagnose urodynamic stress incontinence...
  97. ncbi Long-term outcome of vaginal sacrospinous colpopexy for marked uterovaginal and vault prolapse
    Mohamed A Hefni
    Gynaecology Department, Benenden Hospital, Benenden, Kent TN17 4AX, UK
    Eur J Obstet Gynecol Reprod Biol 127:257-63. 2006
    ..This study was carried out to evaluate the safety and long-term outcome of sacrospinous colpopexy in marked genital prolapse...
  98. ncbi Result of the tension-free vaginal tape in patients with concomitant prolapse surgery: a 2-year follow-up study. An analysis from the Netherlands TVT database
    Steven E Schraffordt Koops
    Department of Gynecology and Obstetrics, Meander Medical Center, Ringweg Randenbroek 110, 3816 CP, Amersfoort, The Netherlands
    Int Urogynecol J Pelvic Floor Dysfunct 18:437-42. 2007
    ..It shows that the procedure in conjunction with prolapse surgery can be safely performed with good results...
  99. ncbi Factors associated with incontinence frequency in a surgical cohort of stress incontinent women
    Holly E Richter
    Division of Medical Surgical Gynecology, Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, USA
    Am J Obstet Gynecol 193:2088-93. 2005
    ..The aim of this study was to identify factors associated with urinary incontinence severity at baseline in women undergoing surgery for stress incontinence...
  100. ncbi Risk factors for failure of transvaginal sacrospinous uterine suspension in the treatment of uterovaginal prolapse
    Tzu Yin Lin
    Urodynamic Unit, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, and Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    J Formos Med Assoc 104:249-53. 2005
    The purpose of this study was to elucidate the risk factors for failure of transvaginal sacrospinous uterine suspension (SSUS) in the treatment of uterine prolapse and to examine methods for controlling these risk factors.
  101. ncbi Lower urinary tract symptoms, quality of life and pelvic organ prolapse: irritative bladder and obstructive voiding symptoms in women planning to undergo abdominal sacrocolpopexy for advanced pelvic organ prolapse
    Holly E Richter
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    J Urol 178:965-9; discussion 969. 2007
    ..We compared lower urinary tract and voiding symptoms in women with and without symptoms of stress urinary incontinence who were planning to undergo abdominal sacrocolpopexy for pelvic organ prolapse...

Research Grants46

  1. A SYSTEM FOR MEASURING PELVIC MUSCLE STRENGTH IN WOMEN
    Neil Cole; Fiscal Year: 2003
    One in nine women suffer from pelvic floor dysfunction, including urinary incontinence and vaginal wall or uterine prolapse (VUP)...
  2. Epidemiology of Female Pelvic Floor Disorders
    Kristen Kjerulff; Fiscal Year: 2001
    ..b>Uterine prolapse is the most common indication for hysterectomy among women aged 60-79, and the second most common indication ..
  3. Improved Surgical Treatment of Pelvic Organ Prolapse
    KEITH LIPFORD; Fiscal Year: 2009
    ..For patients with loss of apical support (vaginal vault or uterine prolapse), restorative surgery is typically performed to repair and prevent vaginal descent...
  4. Pelvic Floor Disorders Network
    CHARLES WILLIAM NAGER; Fiscal Year: 2013
    ..seeking uterine sparing surgery for prolapse and a growing trend of gynecologists and urologists are managing uterine prolapse with vaginal mesh kit procedures...
  5. Mechanisms of anterior vaginal wall support failure
    John O L Delancey; Fiscal Year: 2013
    ..AC prolapse is clinically manifest as the inter-related problems of cystocele and uterine prolapse. Emerging research suggests that AC prolapse involves four fascial failure sites: 1) apical descent, 2) ..
  6. URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERS
    GUNHILDE BUCHSBAUM; Fiscal Year: 2003
    ..A matched pair logistic regression will be performed to obtain an adjusted estimate of the impact of familiality and vaginal delivery in UT and POP, taking into account other risk factors. ..
  7. Female Pelvic Floor Disorders and Sexual Functions
    Victoria Handa; Fiscal Year: 2007
    ..This powerful combination will provide the candidate with the necessary skills and experience to become a successful, independently funded investigator. [unreadable] [unreadable]..
  8. BOTULINUM TOXIN THERAPY FOR INTERSTITIAL CYSTITIS/CHRON*
    Mary FitzGerald; Fiscal Year: 2007
    ..abstract_text> ..
  9. Sensory Testing in Subjects with Interstitial Cystitis
    Mary FitzGerald; Fiscal Year: 2004
    ..abstract_text> ..
  10. A new tool to diagnose female urinary incontinence
    Catherine Bradley; Fiscal Year: 2008
    ..Bradley's research career development. Dr. Bradley has the enthusiastic support of the Colleges of Medicine and Public Health, the Department of Obstetrics and Gynecologv and her mentors and collaborators. ..
  11. Patient-centered goals for pelvic floor dysfunction
    Kathie Hullfish; Fiscal Year: 2004
    ..Patient goals, combined with clinical and QOL measures, may be used to provide comprehensive, multidisciplinary, patient-centered approaches to prevention, management, treatment, and rehabilitation. ..
  12. Conference--National Urology Resident Female Pelvic Med
    Firouz Daneshgari; Fiscal Year: 2006
    ..abstract_text> ..
  13. Natural History of POP-- A Prospective Cohort Study
    Ingrid Nygaard; Fiscal Year: 2005
    ..The national cost burden is large. This project will provide fundamental data to guide future decisions about intervention threshold, preventative measures, and risk factor modification. ..
  14. Function of the Urethra in Continent Women
    Kimberly Kenton; Fiscal Year: 2008
    ..Normative ranges will be calculated for EMG, current perception thresholds, and urethral pressures for Caucasian and African American women. These data can then be used by other centers as reference data. [unreadable] [unreadable]..
  15. Collagenolysis and Elastolysis in Urinary Incontinence
    Bertha Chen; Fiscal Year: 2008
    ..Our goal is to identify specific pathophysiologic changes related to reproductive events and aging which underlie the development of SUI as a first step to identifying potential targets for therapeutic intervention. ..
  16. MOLECULAR AND BIOCHEMICAL STUDY OF COLLAGEN IN PROLAPSE
    Anthony Visco; Fiscal Year: 2002
    ..This study would be the first large-scale comprehensive description of collagen cross-linking, lysine hydroxylation, and of genes coding for enzymes involved in the cross-linking process, in patients with pelvic organ prolapse. ..
  17. Mechanisms of Vaginal Sling Effects on Continence
    Firouz Daneshgari; Fiscal Year: 2006
    ..The long-term goal of this proposal is to expand the findings of this project into an R01 application in order to translate our findings into relevant clinical studies. [unreadable] [unreadable]..
  18. Planning a RCT of Group-Session BMP to Treat Older Adult Women with Incontinence
    Ananias Diokno; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  19. Patient-Oriented Models for Urinary Function in Women
    Linda Brubaker; Fiscal Year: 2008
    ..unreadable] b. To model urinary storage in health and disease [unreadable] c. To model urinary emptying in health and diseas [unreadable] [unreadable]..
  20. Volume-Outcomes in Incontinence Surgery
    Jennifer Anger; Fiscal Year: 2005
    ..The primary outcome will be re-operation rates, repeat sling procedures (for failures), and other postoperative complications, stratified by high and low volume surgeons and hospitals. ..
  21. Assessment of Altered Function in Diabetic Bladder
    Firouz Daneshgari; Fiscal Year: 2005
    ....
  22. Treatment Investigation for Posterior Prolapse
    GEOFFREY CUNDIFF; Fiscal Year: 2005
    ..All subjects will be followed for a total of three years. ..
  23. PKC ALTERATIONS IN LUT DYSFUNCTION
    Firouz Daneshgari; Fiscal Year: 2004
    ..abstract_text> ..
  24. Pelvic Floor Changes Before and After Birth
    REBECCA GLENN ROGERS; Fiscal Year: 2010
    ..This project will provide fundamental data to guide future decisions about labor interventions to prevent PF changes as well as data-based decisions regarding maternal request cesarean. ..
  25. Cesarean After Sphincter Tear (CAST) RCT Planning Grant
    Anthony Visco; Fiscal Year: 2005
    ..The upfront investment of time and resources will result in the submission of an efficient and well-designed R01 application that can be implemented in a timely fashion. ..
  26. BEAUMONT/FORD INTERSTITIAL CYSTITIS CLINICAL CENTER
    Ananias Diokno; Fiscal Year: 2003
    ..The combination therapy will also potentially reduce the dos of BCG, which will lower the cost and decrease the potential morbidity of this treatment program. ..
  27. Limited Access Dataset: The ACTIVE Study
    Sharon Tennstedt; Fiscal Year: 2003
    ..The Coordinating Center for the ACTIVE trial, the New England Research Institutes, will perform this work. ..
  28. Economic Analysis of the Urinary Incontinence Treatment Network Trials (E-UITN)
    Leslee L Subak; Fiscal Year: 2010
    ..The study assembles a group of senior investigators with expertise in economics, cost-effectiveness and UI treatment. The E- UITN will provide critical economic data for commonly used treatments for incontinence. ..
  29. Economic Analysis of the EPRIDE
    Leslee Subak; Fiscal Year: 2008
    ..The E- PRIDE ancillary study allows us to efficiently evaluate the cost-utility of a novel treatment approach - weight reduction -- for incontinence. ..
  30. Interactive Decision Aid for Advance Care Planning
    Sharon Tennstedt; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  31. Beneath the Urologic Iceberg: A Qualitative Study
    Sharon Tennstedt; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  32. IMPACT OF MENOPAUSE ON VAGINAL CONNECTIVE TISSUE SUPPORT
    Pamela Moalli; Fiscal Year: 2008
    ..abstract_text> ..
  33. ADIPOSE DERIVED STEM CELLS FOR TREATMENT OF INCONTINENCE
    LARISSA RODRIGUEZ; Fiscal Year: 2008
    ..Lastly, we will use an animal model of incontinence and decreased urethral resistance to test the hypothesis that these cells can be used to reconstruct a functional urethra as a treatment of stress incontinence. ..
  34. MODEL FOR PELVIC FLOOR DISORDERS
    Amanda Clark; Fiscal Year: 2004
    ..abstract_text> ..
  35. Population Study of Pregnancy and Pelvic Floor Disorders
    Karl Luber; Fiscal Year: 2004
    ..abstract_text> ..
  36. FOOD FOR LIFE: HEALTHIER MEALS ELDERS CAN LIVE WITH
    Sharon Tennstedt; Fiscal Year: 2002
    ..2. To rigorously evaluate the effectiveness of using the package in a workshop in improving participants' diet. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
  37. Reproductive Risk Factors for Pelvic Organ Prolapse
    Jeanette Brown; Fiscal Year: 2004
    ..Identification of risk factors for prolapse will help guide the development of preventive intervention trials to test the efficacy of modifying risk factors for pelvic organ prolapse. ..
  38. Communicating to Improve the Quality of Informal Care
    Sharon Tennstedt; Fiscal Year: 2005
    ....
  39. Race Differences in Female UI: Epidemiology and Biology
    John DeLancey; Fiscal Year: 2005
    ..Knowledge of these factors can then provide the basis for risk factor identification and the development of preventive strategies appropriate to different racial groups. ..
  40. Pittsburgh Collab Reconstructive Pelvic Surgery Program
    Halina Zyczynski; Fiscal Year: 2005
    ..The surgical team is proficient in both surgical approaches and comfortable with the concept of a randomized surgical trial. ..
  41. Doctor-Older Patient Communication About Alcohol Misuse
    Sharon Tennstedt; Fiscal Year: 2006
    ..The program can also be used in medical schools and by advance practice nurses. [unreadable] [unreadable] [unreadable]..
  42. Communicating with Older Drivers: A Web-based Course
    Sharon Tennstedt; Fiscal Year: 2006
    ..The Web-based program will be marketed as a CME product for physicians through NERI's E-commerce Website and the Boston University School of Medicine Office of Continuing Medical Education. [unreadable] [unreadable] [unreadable]..
  43. Training Program for Geriatric Social Workers
    Sharon Tennstedt; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  44. Health Services Use: Analysis of ACTIVE Data
    Sharon Tennstedt; Fiscal Year: 2005
    ..The trial data currently are being archived for public use and are available only to the ACTIVE investigators. ..
  45. Limited Access Dataset: ACTIVE Study Phase II
    Sharon Tennstedt; Fiscal Year: 2007
    ..This project will make the remainder of the study data available for public use. [unreadable] [unreadable] [unreadable]..
  46. ADVANCED STAGE CHRONIC DISEASE: SYMPTONS, DISTRESS, CARE
    Sharon Tennstedt; Fiscal Year: 2002
    ..Finally, the study will provide data on the amount, source, and costs of care that will improve planning and coordination of end-of-life care. ..