iritis

Summary

Summary: Inflammation of the iris characterized by circumcorneal injection, aqueous flare, keratotic precipitates, and constricted and sluggish pupil along with discoloration of the iris.

Top Publications

  1. ncbi An unusual case of late ocular changes after lightning injury
    Himadri Datta
    Department of Ophthalmology, Bankura Sammilani Medical College, Bankura, West Bengal, India
    Indian J Ophthalmol 50:224-5. 2002
  2. ncbi Ocular involvement as the initial manifestation of Wegener's granulomatosis in children
    Michelle Levi
    North Shore Long Island Jewish Health System, Great Neck, New York, USA
    J AAPOS 12:94-6. 2008
  3. ncbi Iritis and pupillary distortion after periorbital cosmetic alexandrite laser
    Chih Chung Lin
    Department of Ophthalmology, Taipei City Hospital, Renai Branch, No 10, Sec 4, Ren Ai Rd, Taipei, 106, Taiwan, Republic of China
    Graefes Arch Clin Exp Ophthalmol 249:783-5. 2011
  4. ncbi Iritis associated with intravenous cidofovir
    A L Tseng
    The Toronto Hospital, Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Ann Pharmacother 33:167-71. 1999
  5. ncbi Metipranolol-associated granulomatous iritis
    R B Melles
    Department of Ophthalmology, Kaiser Permanente Medical Center, Redwood City, CA 94063
    Am J Ophthalmol 118:712-5. 1994
  6. ncbi Recurrent iritis after implantation of an iris-fixated phakic intraocular lens for the correction of myopia Case report and clinicopathologic correlation
    Guy Kleinmann
    Laboratories for Ophthalmic Devices Research, John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah 84132, USA
    J Cataract Refract Surg 32:1385-7. 2006
  7. ncbi Placement of a collagen glaucoma drainage device to control intraocular pressure and chronic iritis secondary to juvenile rheumatoid arthritis
    Francis W Price
    Price Vision Group, Indianapolis, Indiana 46260 5354, USA
    Ophthalmic Surg Lasers 33:233-6. 2002
  8. ncbi Pouchitis-associated iritis (uveitis) following total proctocolectomy and ileal pouch-to-anal anastomosis in ulcerative colitis
    H J Freeman
    Gastroenterology, ACU F-137, University of British Columbia Hospital, 2211 Wesbrook Mall, Vancouver, British Columbia V6T 1W5, Canada
    Can J Gastroenterol 15:131-3. 2001
  9. pmc Blockage of complement regulators in the conjunctiva and within the eye leads to massive inflammation and iritis
    D S Bardenstein
    Institute of Pathology, Center for Vision Research, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Immunology 104:423-30. 2001
  10. ncbi The interrelationship between sex, susceptibility factors, and outcome in ankylosing spondylitis and its associated disorders including inflammatory bowel disease, psoriasis, and iritis
    Sinead Brophy
    Epidemiology Department, Royal National Hospital for Rheumatic Disease, Upper Borough Walls, Bath BA1 1RL, UK
    J Rheumatol 30:2054-8. 2003

Research Grants

  1. ENDOTOXIN INDUCED UVEITIS
    James Rosenbaum; Fiscal Year: 2000
  2. IONTOPHORESIS OF ARA-AMP TO HERPES VIRUS LESIONS
    James Hill; Fiscal Year: 1980
  3. HERPES EYE DISEASE
    Roy Beck; Fiscal Year: 2000
  4. FOUR DIMENSIONAL IMAGING OF THE IMMUNE RESPONSE IN VIVO
    James T Rosenbaum; Fiscal Year: 2010
  5. UVEITIS GENE-EXPRESSION PROFILING
    James Rosenbaum; Fiscal Year: 2008
  6. Endotoxin-induced Uveitis Revisited
    James T Rosenbaum; Fiscal Year: 2010
  7. Iron Deficiency and Anemia in HIV and HCV-Infected Women
    Richard Semba; Fiscal Year: 2005
  8. Hepcidin and the pathogenesis of anemia in older adults.
    Richard D Semba; Fiscal Year: 2010
  9. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
  10. OCULAR HERPES SIMPLEX
    Herbert Kaufman; Fiscal Year: 2008

Detail Information

Publications182 found, 100 shown here

  1. ncbi An unusual case of late ocular changes after lightning injury
    Himadri Datta
    Department of Ophthalmology, Bankura Sammilani Medical College, Bankura, West Bengal, India
    Indian J Ophthalmol 50:224-5. 2002
    We describe a case of late ocular changes after lightning injury. One year after the injury, complete ankyloblepharon, severe dry eye, corneal opacity, healed iritis and mature cataracts were noted in both eyes of the patient.
  2. ncbi Ocular involvement as the initial manifestation of Wegener's granulomatosis in children
    Michelle Levi
    North Shore Long Island Jewish Health System, Great Neck, New York, USA
    J AAPOS 12:94-6. 2008
    ..The disease may present initially with ocular manifestations. We report the largest series to date of children whose ocular findings were the initial presenting signs of Wegener's granulomatosis...
  3. ncbi Iritis and pupillary distortion after periorbital cosmetic alexandrite laser
    Chih Chung Lin
    Department of Ophthalmology, Taipei City Hospital, Renai Branch, No 10, Sec 4, Ren Ai Rd, Taipei, 106, Taiwan, Republic of China
    Graefes Arch Clin Exp Ophthalmol 249:783-5. 2011
    ....
  4. ncbi Iritis associated with intravenous cidofovir
    A L Tseng
    The Toronto Hospital, Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Ann Pharmacother 33:167-71. 1999
    To report two patients with AIDS and cytomegalovirus retinitis who developed iritis after receiving intravenous cidofovir. Both experienced recurrent symptoms upon rechallenge.
  5. ncbi Metipranolol-associated granulomatous iritis
    R B Melles
    Department of Ophthalmology, Kaiser Permanente Medical Center, Redwood City, CA 94063
    Am J Ophthalmol 118:712-5. 1994
    ..We studied granulomatous uveitis reactions to topical metipranolol 0.3% therapy for primary open-angle glaucoma in two patients in the United States...
  6. ncbi Recurrent iritis after implantation of an iris-fixated phakic intraocular lens for the correction of myopia Case report and clinicopathologic correlation
    Guy Kleinmann
    Laboratories for Ophthalmic Devices Research, John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah 84132, USA
    J Cataract Refract Surg 32:1385-7. 2006
    ..We report the case of a young healthy patient who experienced persistent and intolerable iritis after implantation of an iris-claw IOL. The iritis was resolved only after explantation of the IOL.
  7. ncbi Placement of a collagen glaucoma drainage device to control intraocular pressure and chronic iritis secondary to juvenile rheumatoid arthritis
    Francis W Price
    Price Vision Group, Indianapolis, Indiana 46260 5354, USA
    Ophthalmic Surg Lasers 33:233-6. 2002
    A patient with juvenile rheumatoid arthritis and chronic iritis is reported with intraocular pressure near 30 mm Hg and previous episodes of intraocular pressure as high as 50 mm Hg despite maximally tolerated medical therapy...
  8. ncbi Pouchitis-associated iritis (uveitis) following total proctocolectomy and ileal pouch-to-anal anastomosis in ulcerative colitis
    H J Freeman
    Gastroenterology, ACU F-137, University of British Columbia Hospital, 2211 Wesbrook Mall, Vancouver, British Columbia V6T 1W5, Canada
    Can J Gastroenterol 15:131-3. 2001
    ..Although no ophthalmological manifestations were present before the staged surgical procedures, iritis developed after appearance of the pouchitis...
  9. pmc Blockage of complement regulators in the conjunctiva and within the eye leads to massive inflammation and iritis
    D S Bardenstein
    Institute of Pathology, Center for Vision Research, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Immunology 104:423-30. 2001
    ..blockage of 5I2 Ag function in periocular tissues and within the eye causes intense conjunctival inflammation and iritis demonstrates the importance of intrinsic complement regulators in protecting ocular tissues from spontaneous or ..
  10. ncbi The interrelationship between sex, susceptibility factors, and outcome in ankylosing spondylitis and its associated disorders including inflammatory bowel disease, psoriasis, and iritis
    Sinead Brophy
    Epidemiology Department, Royal National Hospital for Rheumatic Disease, Upper Borough Walls, Bath BA1 1RL, UK
    J Rheumatol 30:2054-8. 2003
    ..This suggests that either women with disease carry more susceptibility factors than men or that the uterine environment/breast feeding may play a role in AS...
  11. ncbi Hypopyon iritis after primary fresh amniotic membrane transplantation
    Renuka Srinivasan
    Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
    Cornea 26:1275-6. 2007
    To report the occurrence of hypopyon iritis after primary, fresh amniotic membrane transplant (AMT).
  12. ncbi Herpetic keratitis with iritis after corneal crosslinking with riboflavin and ultraviolet A for keratoconus
    George D Kymionis
    Department of Ophthalmology, University of Crete, Crete, Greece
    J Cataract Refract Surg 33:1982-4. 2007
    ..Five days postoperatively, she presented with geographic epithelial keratitis and iritis. Analysis of tear samples by polymerase chain reaction confirmed the diagnosis...
  13. ncbi Effect of etanercept on iritis in patients with ankylosing spondylitis
    James T Rosenbaum
    Arthritis Rheum 50:3736-7. 2004
  14. ncbi Cyclosporin-augmented laser peripheral iridoplasty
    Earl R Crouch
    Thomas R Lee Center for Ocular Pharmacology, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Ophthalmic Surg Lasers Imaging 35:475-81. 2004
    Almost all patients develop iritis following argon laser peripheral iridoplasty. Numerous adverse effects, particularly elevated intraocular pressure (IOP) and reduced microbial resistance, complicate therapy with topical corticosteroids...
  15. ncbi Effects of pupil stretch technique during phacoemulsification on postoperative vision, intraocular pressure, and inflammation
    Bradford J Shingleton
    Ophthalmic Consultants of Boston, Boston, Massachusetts 02114, USA
    J Cataract Refract Surg 32:1142-5. 2006
    ..To determine whether pupil stretch during phacoemulsification affects postoperative best corrected visual acuity (BCVA), intraocular pressure (IOP), and inflammation compared with results in patients without pupil stretch...
  16. ncbi Enhanced ocular anti-inflammatory activity of ibuprofen carried by an Eudragit RS100 nanoparticle suspension
    Claudio Bucolo
    Bausch and Lomb Fidia Oftal Pharmaceuticals, Catania, Italy
    Ophthalmic Res 34:319-23. 2002
    ..To investigate the ocular pharmacodynamic profile of a polymer nanoparticle system loaded with sodium ibuprofen (IBU-RS) in comparison to an aqueous solution of ibuprofen lysinate (IBL) in the rabbit eye both being applied topically...
  17. ncbi Collamer intraocular lens implantation with active uveitis
    Jonathan Stanwood Till
    Lewis Gale Clinic, Salem, VA 24153, USA
    J Cataract Refract Surg 29:2439-43. 2003
    Two patients with active iritis developed cataracts and had successful cataract surgery with implantation of a Collamer (Staar Surgical, AG) intraocular lens (IOL)...
  18. ncbi Ocular manifestations in Blau syndrome associated with a CARD15/Nod2 mutation
    Toru Kurokawa
    Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Ophthalmology 110:2040-4. 2003
    ..To report cases of Blau syndrome with a CARD15/Nod2 mutation...
  19. ncbi Risks of intravitreous injection: a comprehensive review
    Rama D Jager
    The Beetham Eye Institute, Joslin Diabetes Center and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
    Retina 24:676-98. 2004
    ..To evaluate the prevalence of the most common serious adverse events associated with intravitreous (IVT) injection...
  20. ncbi Management of the red eye for the primary care physician
    Christopher Wirbelauer
    Klinik fur Augenheilkunde, Vivantes Klinikum Neukölln, Berlin, Germany
    Am J Med 119:302-6. 2006
    ..The most frequent causes of a red eye, such as dry eye, conjunctivitis, keratitis, iritis, acute glaucoma, subconjunctival hematoma, foreign bodies, corneal abrasion, and blunt or penetrating trauma, are ..
  21. ncbi The natural history of ankylosing spondylitis as defined by radiological progression
    Sinead Brophy
    Royal National Hospital for Rheumatic Diseases, Bath, UK
    J Rheumatol 29:1236-43. 2002
    ..Radiological status is an important objective endpoint in the assessment of ankylosing spondylitis (AS). We investigated the disease development of AS using radiological change...
  22. ncbi A longitudinal study of disease activity and functional status in a hospital cohort of patients with ankylosing spondylitis
    L P Robertson
    Rheumatology, Bristol Royal Infirmary, Bristol, UK
    Rheumatology (Oxford) 43:1565-8. 2004
    ....
  23. ncbi Inflammatory eye, skin, and bowel disease in spondyloarthritis: genetic, phenotypic, and environmental factors
    S Brophy
    Epidemiology Department, Royal National Hospital for Rheumatic Diseases, Bath, UK
    J Rheumatol 28:2667-73. 2001
    ..e., ankylosing spondylitis (AS), psoriasis, iritis, inflammatory bowel disease (IBD)]...
  24. ncbi Effects of enzymatic sterilization detergents on the corneal endothelium
    Chirag Parikh
    Emory Eye Center, 1365 B Clifton Rd NE, Suite B2600, Atlanta, GA 30322, USA
    Arch Ophthalmol 120:165-72. 2002
    ..To evaluate the potential of enzymatic detergents to cause endothelial damage and anterior segment inflammation...
  25. ncbi COX-2 inhibitors prolong trauma-induced elevations of iris hyaluronan
    Anna Koralewska-Makár
    Department of Ophthalmology, University of Lund, Lund, Sweden
    J Ocul Pharmacol Ther 19:385-95. 2003
    To investigate whether and how treatment with COX-2 inhibitors influences hyaluronan responses to a standardized trauma, argon laser induced iritis, in rabbits.
  26. ncbi The red eye
    F Hampton Roy
    University of Arkansas Medical Science Campus, Little Rock, AR, USA
    Ann Ophthalmol (Skokie) 38:35-8. 2006
    ..Ciliary injection indicates inflammation of the cornea, iris, or ciliary body, whereas conjunctival injection mainly affects the posterior conjunctival blood vessels...
  27. ncbi Endogenous pneumococcal endophthalmitis followed by pneumococcal-induced uveitis
    Fabio Nessi
    Hopital Ophtalmique Jules Gonin, Lausanne, Suisse
    Klin Monbl Augenheilkd 220:204-6. 2003
    ..We describe the case of a fulminant bilateral endophthalmitis occurring in a patient, who had 9 years earlier a splenectomy for an idiopathic thrombocytopenic purpura...
  28. ncbi [Glaucoma related with photoreceptor outer segments in aqueous humor. Schwartz-Matsuo syndrome]
    C Gutierrez
    Servicio de Oftalmologia, Hospital Ramon y Cajal, Madrid
    Arch Soc Esp Oftalmol 76:315-8. 2001
    ..DISCUSSION: The presence of photoreceptor outer segments in aqueous humor confirms the diagnosis of Schwartz-Matsuo syndrome, which should be considered as a differential diagnosis of iritis and glaucoma.
  29. ncbi [Ophthalmological emergencies. 1. The acute red eye]
    B Gabler
    Augenklinik, Universitat Regensburg
    MMW Fortschr Med 144:39-40. 2002
  30. ncbi Long-term acyclovir use to prevent recurrent ocular herpes simplex virus infection
    Uchoandro B C Uchoa
    Cornea Service, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Arch Ophthalmol 121:1702-4. 2003
    ..To evaluate the effectiveness of more than 12 months of oral acyclovir therapy in reducing recurrences of ocular herpes simplex virus...
  31. ncbi Severe iritis and choroidal effusion following selective laser trabeculoplasty
    Danny Y Kim
    University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    Ophthalmic Surg Lasers Imaging 39:409-11. 2008
    ..The authors believe this is the first reported case of severe iritis and choroidal effusion following selective laser trabeculoplasty.
  32. ncbi Diffuse lamellar keratitis associated with iritis 10 months after laser in situ keratomileusis
    V A Keszei
    621 Memorial Drive, Suite 512, South Bend, IN 46601, USA
    J Cataract Refract Surg 27:1126-7. 2001
    ..The DLK was associated with acute iritis, not with manipulation of the LASIK flap or epithelium...
  33. ncbi Clinical performance of Alcon SA30AL and SA60AT single-piece acrylic intraocular lenses
    James A Davison
    Department of Ophthalmology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
    J Cataract Refract Surg 28:1112-23. 2002
    ..To report the clinical performance characteristics of single-piece acrylic Alcon SA30AL and SA60AT intraocular lenses (IOLs)...
  34. pmc Chlamydiae as etiologic agents in chronic undifferentiated spondylarthritis
    John D Carter
    University of South Florida College of Medicine, Tampa, FL 33612, USA
    Arthritis Rheum 60:1311-6. 2009
    ..with Chlamydia-induced reactive arthritis do not present with the classic triad of arthritis, conjunctivitis/iritis, and urethritis. Moreover, acute chlamydial infections are often asymptomatic...
  35. ncbi Epidemiological survey of intraocular inflammation in Japan
    Hiroshi Goto
    Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan
    Jpn J Ophthalmol 51:41-4. 2007
    ..To report the frequency and trend of intraocular inflammation based on a survey of new ophthalmology patient visits to university hospitals throughout Japan during 2002...
  36. ncbi An eye on inflammatory eye disease
    P G Kestelyn
    Afdeling Oogheelkunde, Universitair Ziekenhuis, Gent
    Acta Clin Belg 60:270-5. 2005
    ..nongranulomatous, unilateral, anterior uveitis) and matched (meshing) to a potential list of etiologies (eg, viral iritis, HLA-B 27 associated iritis)...
  37. pmc Surgical results of triamcinolone assisted pars plana vitrectomy combined with phacoemulsification in diabetic patients
    Hakki Birinci
    Department of Ophthalmology, Medical Faculty, University of Ondokuz Mayis, Turkey
    Open Ophthalmol J 2:5-8. 2008
    ....
  38. ncbi The use of cytokine-stimulated healthy donors in allogeneic stem cell transplantation
    Simone Cesaro
    Clinic of Pediatric Oncology Hematology, Department of Pediatrics, University of Padova, Via Giustiniani 3, 35128 Padua, Italy
    Haematologica 87:35-41. 2002
    ..to the stimulation of healthy donors with rhG-CSF but the description of cases of non-traumatic splenic rupture, iritis, cardiac ischemia, and gouty arthritis suggests that further precautionary restrictions are advisable when ..
  39. ncbi The genetics of spondyloarthropathies
    K Y Fong
    Department of Medicine, National University of Singapore, Singapore
    Ann Acad Med Singapore 29:370-5. 2000
    ..Ocular involvement like uveitis, iritis and conjunctivitis can be present in up to a third of the patients...
  40. ncbi Friedrich August von Ammon (1799-1861)
    D M Reifler
    Michigan State University College of Human Medicine GRAMEC, Grand Rapids, USA
    Doc Ophthalmol 99:199-213. 1999
    ..His prize-winning treatise, De Iritide (1835), correctly categorized iritis and gave a detailed description of sympathetic ophthalmia...
  41. ncbi Drug-induced ocular inflammatory diseases
    Frederick W Fraunfelder
    The National Registry of Drug Induced Ocular Side Effects, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239 4197, USA
    Drugs Today (Barc) 43:117-23. 2007
    ..g., iritis, pars planitis or iridocyclitis...
  42. ncbi Cystoid macular edema following immune recovery and treatment with cidofovir for cytomegalovirus retinitis
    A J Kersten
    Augenklinik der Heinrich Heine Universität, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Graefes Arch Clin Exp Ophthalmol 237:893-6. 1999
    ..Cidofovir has proved to be highly effective in treatment of CMV retinitis. Iritis and bulbar hypotony are known as the major complications after intravenous and intravitreal use of this antiviral ..
  43. ncbi Sequential bilateral solitary extramedullary plasmacytoma of the ciliary body
    Carol L Shields
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cornea 26:759-61. 2007
    ..To report bilateral plasmacytoma of the ciliary body in a healthy patient...
  44. ncbi [Lightning injuries: case report of a 17-year-old man and a brief review of the literature]
    N Stutz
    Abteilung für Plastische, Hand und Wiederherstellungschirurgie, Zentrum für Schwerbrandverletzte, Klinikum Nürnberg Süd, Breslauerstrasse 201, 90471 Nürnberg
    Unfallchirurg 109:495-8. 2006
    ..The patient suffered transient symptoms, including pain, loss of consciousness, tinnitus, iritis and paresthesia...
  45. ncbi Effects of intracameral administration of α-chymotrypsin on intracapsular lens extraction and postoperative outcome in clinically normal dogs
    David J Maggs
    Department of Veterinary Medicine and Surgery College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Am J Vet Res 71:1475-83. 2010
    ..To assess the intraoperative and postoperative clinical effects and histologic effects of intracameral administration of α-chymotrypsin in clinically normal dogs undergoing standard intracapsular lens extraction (ICLE)...
  46. ncbi [Ocular injuries related to Independence Day celebrations]
    Assaf Kratz
    Department of Ophthalmology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Harefuah 145:254-6, 320. 2006
    ..This study aims to describe and characterize the ocular injuries that are directly related to the use of these devices...
  47. ncbi Diagnosis and management of red eye in primary care
    Holly Cronau
    Department of Family Medicine, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Am Fam Physician 81:137-44. 2010
    ..Other common causes include blepharitis, corneal abrasion, foreign body, subconjunctival hemorrhage, keratitis, iritis, glaucoma, chemical burn, and scleritis...
  48. ncbi Phacoemulsification in eyes with white cataract
    A Chakrabarti
    Aravind Eye Hospital and PG Institute of Ophthalmology, Tamilnadu, India
    J Cataract Refract Surg 26:1041-7. 2000
    ..To study the results of phacoemulsification in eyes with white cataract...
  49. ncbi Hepatitis B vaccine and uveitis: an emerging hypothesis suggested by review of 32 case reports
    Frederick W Fraunfelder
    Casey Eye Institute, Portland, Oregon 97239, USA
    Cutan Ocul Toxicol 29:26-9. 2010
    ..To report a possible association between hepatitis B vaccine and uveitis...
  50. ncbi Diverse virulence of Staphylococcus aureus strains for the conjunctiva
    Clare C McCormick
    Department of Microbiology, University of Mississippi Medical Center, 2500 N State St, Jackson, MS 39216, USA
    Curr Eye Res 36:14-20. 2011
    ..To determine the virulence of Staphylococcus aureus strains in the rabbit conjunctiva...
  51. ncbi The ocular complications of smallpox and smallpox immunization
    Richard D Semba
    Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Arch Ophthalmol 121:715-9. 2003
    ..ocular complications, including eyelid and conjunctival infection, corneal ulceration, disciform keratitis, iritis, optic neuritis, and blindness...
  52. ncbi Search for autoantibodies against the HNK-1 carbohydrate epitope in the human eye in intermediate uveitis
    M Uusitalo
    Department of Ophthalmology, Helsinki University Central Hospital, Finland
    Acta Ophthalmol Scand 78:536-8. 2000
    ..We investigated whether autoantibodies to these molecules can be detected in patients with intermediate uveitis, which affects the ciliary body...
  53. ncbi Nonclinical safety and pharmacokinetics of intravitreally administered human-derived plasmin in rabbits and minipigs
    Joel W Proksch
    Global Preclinical Development, Bausch and Lomb, Rochester, NY 14609, USA
    J Ocul Pharmacol Ther 24:320-32. 2008
    ..Effects at the higher doses included myosis, iritis, iridolenticular synechiae, and changes in electroretinogram waveforms and parameters that were generally not ..
  54. ncbi Bioadhesive sulfacetamide sodium microspheres: evaluation of their effectiveness in the treatment of bacterial keratitis caused by Staphylococcus aureus and Pseudomonas aeruginosa in a rabbit model
    Demet Sensoy
    Department of Pharmaceutical Technology, Istanbul University, Istanbul, Turkey
    Eur J Pharm Biopharm 72:487-95. 2009
    ..therapy, the eyes were examined in respect to clinical signs of infection (blepharitis, conjunctivitis, iritis, corneal oedema and corneal infiltrates) which are the main symptoms of bacterial keratitis and then cornea ..
  55. ncbi [Trypan blue capsule staining for phacoemulsification in white cataract]
    M Cheour
    Service d Ophtalmologie, Hopital Habib Thameur, Tunis, Tunisie
    J Fr Ophtalmol 30:914-7. 2007
    ..To study the results of phacoemulsification in eyes with white cataract using trypan blue for capsule staining...
  56. ncbi Treatment of viral diseases of the cornea and external eye
    H E Kaufman
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans 70112, USA
    Prog Retin Eye Res 19:69-85. 2000
    ..New studies indicate that herpetic stromal disease and iritis are effectively treated with a combination of corticosteroid and antiviral without additional risk...
  57. ncbi Sympathetic ophthalmia in vater association combined with persisting hyperplastic primary vitreous after cyclodestructive procedure
    J B Jonas
    Department of Ophthalmology, Faculty of Clinical Medicine Mannheim, Ruprecht Karls University of Heidelberg, Mannheim, Germany
    Eur J Ophthalmol 16:171-2. 2006
    ....
  58. ncbi Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage
    Baruch D Kuppermann
    Department of Ophthalmology, University of California, Irvine, Irvine 92697, California
    Am J Ophthalmol 140:585-97. 2005
    ..To evaluate the safety of intravitreous ovine hyaluronidase for the management of vitreous hemorrhage...
  59. ncbi [Ulcerative esophagitis and colitis as rare manifestations of Adamantiades-Behcet disease]
    R Glosemeyer
    Medizinische Klinik, Klinikum Bayreuth
    Z Gastroenterol 39:167-71. 2001
    ..In the course of the disease she developed recurrent iritis, nodular skleritis, oral and genital ulcer, erythema nodosum and axillary folliculitis...
  60. pmc Collecting a set of psoriasis family material through a patient organisation; clinical characterisation and presence of additional disorders
    Annica Inerot
    Department of Dermatology, Sahlgrenska University Hospital Sahlgrenska, SE 413 45 Goteborg, Sweden
    BMC Dermatol 5:10. 2005
    ..Furthermore, we wanted to compare siblings with and without psoriasis regarding the occurrence of other diseases...
  61. ncbi [Ocular syphilis]
    Dieter Schmidt
    Augenklinik, Universitat Freiburg
    Klin Monbl Augenheilkd 219:433-9. 2002
    ..Syphilis has distinctly increased in the last decades. It is necessary to know the different eye changes in syphilis...
  62. pmc Efficacy of a helicase-primase inhibitor in animal models of ocular herpes simplex virus type 1 infection
    Herbert E Kaufman
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center in New Orleans, New Orleans, LA, USA
    J Ocul Pharmacol Ther 24:34-42. 2008
    ..The aim of this study was to evaluate the effect of BAY 57-1293, a helicase-primase inhibitor, on herpes simplex virus type 1 (HSV-1) reactivation in mice and its efficacy on established disease in rabbits...
  63. ncbi Feasibility of bimanual microincision phacoemulsification in hard cataracts
    A Assaf
    Department of Ophthalmology, Ain Shams University, Nasr City, Cairo, Egypt
    Eye (Lond) 21:807-11. 2007
    ..The purpose of this work was to assess the feasibility of bimanual phacoemulsification in hard cataracts of N3+ using WhiteStar technology of Soveriegn (Advanced Medical Optics, Santa Ana, CA, USA)...
  64. ncbi Analysis of uveitis rates across all etanercept ankylosing spondylitis clinical trials
    J Sieper
    Universitatsmedizin Berlin, Campus Benjamin Franklin, Med Klinik I Rheumatologie, Hindenburgdamm 30, 12200 Berlin, Germany
    Ann Rheum Dis 69:226-9. 2010
    To assess uveitis (including iritis and iridocyclitis) incidence from clinical trials of etanercept in patients with ankylosing spondylitis (AS).
  65. ncbi [A case of panuveitis with optic disc neovascularization associated with juvenile idiopathic arthritis which progressed during a clinical trial of etanercept]
    Reiko Kinouchi
    Department of Ophthalmology, Asahikawa Medical College, Japan
    Nihon Ganka Gakkai Zasshi 111:970-5. 2007
    To report a case of uveitis associated with juvenile idiopathic arthritis that progressed from iritis to panuveitis with disc neovascularization during a clinical trial of etanercept, a tumor necrosis factor a (TNF-alpha) blocker.
  66. ncbi Intravenous cidofovir for compassionate use in AIDS patients with cytomegalovirus retinitis. Spanish Cidofovir Study Group
    J Berenguer
    Servicio de Microbiologia y Enfermedades Infecciosas, Hospital Gregorio Maranon, 28007, Madrid, Spain
    Clin Infect Dis 30:182-4. 2000
    ..Two deaths were considered related to the drug. Iritis developed in 21 patients (41.2%), a frequency higher than that reported during the pre-HAART era...
  67. ncbi Intraocular inflammation following intravitreal injection of bevacizumab
    Sophie J Bakri
    Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Graefes Arch Clin Exp Ophthalmol 246:779-81. 2008
    ..Failure to recognize an eye with anterior chamber and vitreous cell as sterile inflammation can lead to unnecessary treatment for endophthalmitis...
  68. ncbi Longterm visual prognosis of patients with ocular Adamantiades-Behçet's disease treated with interferon-alpha-2a
    Lothar Krause
    Department of Ophthalmology, Charite Universitaetsmedizin Berlin, Berlin, Germany
    J Rheumatol 35:896-903. 2008
    ..Interferon-alpha (IFN-alpha) has proven to be effective in mucocutaneous ABD and has been reported to improve ocular lesions. We examined the longterm effects of IFN-alpha-2a in a case series of 45 patients with ocular involvement...
  69. ncbi An outbreak of iritis and uveitis in dairy cattle at pasture associated with the supplementary feeding of baleage
    R A Laven
    N Z Vet J 54:151-2. 2006
  70. ncbi [F99, a mental disorder not otherwise specified]
    Ville Levänen
    Duodecim 119:343, 345. 2003
  71. ncbi Uveitis associated with West Nile virus infection
    Rachel W Kuchtey
    Arch Ophthalmol 121:1648-9. 2003
  72. ncbi Iritis presumed as secondary to disseminated coccidioidomycosis
    Julie M Hwang
    VA Greater Los Angeles Healthcare System, Los Angeles, California, USA
    Optometry 77:547-53. 2006
    ..Ocular involvement may include anterior segment, posterior segment, or extraorbital involvement...
  73. ncbi Bilateral ankle edema with bilateral iritis
    Sunil Kumar
    Department of Ophthalmology, Mohammad Dossary Hospital, PO Box 335 Al Khobar 31952, Kingdom of Saudi Arabia
    Clin Rheumatol 26:1145-7. 2007
    I report two patient presented to me with bilateral symmetrical ankle edema and bilateral acute iritis. A 42-year-old female of Indian origin and 30-year-old female from Somalia both presented with bilateral acute iritis...
  74. ncbi Tubulointerstitial nephritis and uveitis syndrome associated with hyperthyroidism
    Itaru Ebihara
    Department of Nephrology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, and Department of Nephrology, Tokyo Medical University Kasumigaura Hospital, Ibaraki, 311 4198, Japan
    Clin Exp Nephrol 10:216-21. 2006
    ..He had iritis, which was complicated by fibrin in the anterior chamber, diagnosed by slit-lamp examination...
  75. ncbi [The Greek and the Turk: Benediktos Adamantiades (1875-1965) and Hulûsi Behçet (1889-1948)]
    W Keitel
    Z Rheumatol 62:88-94. 2003
  76. ncbi Clinically unsuspected diffuse uveal melanoma presenting as recurrent iritis
    Benjamin Mathew
    Department of Ophthalmology, University of Ottawa Eye Institute, University of Ottawa, The Ottawa Hospital, Ottawa, Ont
    Can J Ophthalmol 39:464-7. 2004
  77. ncbi Cat-scratch uveitis confirmed by histological, serological, and molecular diagnoses
    Ramon L Font
    Ophthalmic Pathology Laboratory, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA
    Cornea 30:468-71. 2011
    ..To report a case of a cat-scratch uveitis caused by Bartonella henselae, which was confirmed by histology, serology, and polymerase chain reaction (PCR) methodology...
  78. pmc Susceptibility of human iris stromal cells to herpes simplex virus 1 entry
    John Baldwin
    Department of Microbiology and Immunology, Midwestern University, Downers Grove, Illinois, USA
    J Virol 87:4091-6. 2013
    Ocular herpes simplex virus 1 (HSV-1) infection can lead to multiple complications, including iritis, an inflammation of the iris...
  79. ncbi Two cases of SAPHO syndrome accompanied by classic features of Behcet's disease and review of the literature
    Hiroki Yabe
    Department of Orthopaedic Surgery, National Hospital Organization Tokyo Medical Center, Higashigaoka 2 5 1, Meguro ku, Tokyo, 152 8902, Japan
    Clin Rheumatol 27:133-5. 2008
    ..Another conspicuous complication was bilateral glaucoma and episodes of iritis were recognized during the follow-up period...
  80. pmc Frequency and characteristics of disease flares in ankylosing spondylitis
    Roxanne Cooksey
    School of Medicine, Swansea University, Swansea, UK
    Rheumatology (Oxford) 49:929-32. 2010
    ..To examine the characteristics and frequency of disease flares in a cohort of people with AS...
  81. ncbi Association between ocular injuries and internal orbital fractures
    Dongmei He
    University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
    J Oral Maxillofac Surg 65:713-20. 2007
    ..This study was performed to assess the association between orbital blowout fractures and ocular injuries...
  82. ncbi Traumatic macular hole from intentional basketball overinflation
    Yoshihiro Yonekawa
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmic Surg Lasers Imaging Retina 44:303-5. 2013
    ..A basketball was intentionally overinflated until it exploded, resulting in corneal edema, hyphema, iritis, vitreous hemorrhage, commotio retinae, and a macular hole...
  83. pmc Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods
    Els Adriaens
    Adriaens Consulting BVBA, Bellem, Belgium
    Arch Toxicol 88:701-23. 2014
    ..b>Iritis was found to rarely drive the classification (<4 % of both Cat 1 and Cat 2 chemicals)...
  84. ncbi Uveitic secondary glaucoma: influence in James Joyce's (1882-1941) last works
    Francisco J Ascaso
    Department of Ophthalmology, University Clinic Hospital, San Juan Bosco Avenue 15, 50009 Zaragoza, Spain
    J Med Biogr 18:57-60. 2010
    ..Could Ulysses and Finnegans wake have been different if Joyce's visual problems had begun in the second rather than the first half of 20th century?..
  85. ncbi Clinical outcome of iridotomy with Argon-YAG laser at a tertiary care center in Karachi, Pakistan
    Rashid Baig
    Section of Ophthalmology, Department of Surgery, Aga Khan University, Karachi, Pakistan
    J Pak Med Assoc 60:220-3. 2010
    ..To assess the the efficacy and early and late complications of Argon-YAG combined laser iridotomy in the outpatient department of a tertiary care hospital...
  86. ncbi [The clinical characters of 30 patients with enteropathic arthritis and literature review]
    Jiang Lin Zhang
    Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China
    Zhonghua Nei Ke Za Zhi 49:223-5. 2010
    ..To better understand the clinical characters of enteropathic arthritis patients...
  87. ncbi [Cataract surgery in nanophthalmic eyes]
    D Pahor
    Department of Ophthalmology, University Clinical Centre Maribor, Maribor, Slovenia
    Klin Monbl Augenheilkd 229:1113-7. 2012
    ..The aim of this study was to determine the prevalence of nanophthalmos among cataract patients and to evaluate intraoperative and postoperative complications in nanophthalmic eyes...
  88. ncbi Anti-TNF alpha therapy in the management of extraintestinal manifestation of inflammatory bowel disease
    G Andrisani
    Complesso Integrato Columbus, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Eur Rev Med Pharmacol Sci 16:890-901. 2012
    ..Some extraintestinal manifestations such as arthritis, erytema nodosum, pyoderma gangrenosum, iritis, uveitis have a pathogenic tumor necrosis factor alpha-dependent mechanism common with Crohn's disease and ..
  89. ncbi Clinical statistics of endogenous uveitis: comparison between general eye clinic and university hospital
    J I Sakai
    Department of Ophthalmology, Tokyo Medical University, 6 7 1 Nishi shinjuku, Shinjuku ku, Tokyo, 160 0023, Japan
    Int Ophthalmol 30:297-301. 2010
    ..We observed that diabetic iritis and herpetic iritis were significantly more frequent in the clinic whereas Vogt-Koyanagi-Harada disease and Behcet'..
  90. ncbi Outcomes of high volume cataract surgeries at a Lions Sight First Eye Hospital in Kenya
    Jyotee Trivedy
    Lions Sight First Eye Hospital, Loresho, Kenya
    Nepal J Ophthalmol 3:31-8. 2011
    ..High volume cataract surgery is practised in many eye centres...
  91. ncbi A 5-year, randomized, open-label safety study of latanoprost and usual care in patients with open-angle glaucoma or ocular hypertension
    I Goldberg
    Eye Associates, Glaucoma Services, Sydney Eye Hospital, University of Sydney Australia
    Eur J Ophthalmol 18:408-16. 2008
    ..To investigate the incidence of latanoprost-related adverse events of the cornea, iris, and retina and the occurrence of hyperpigmentation...
  92. ncbi [Portrait of the artist as a sick man. Rheumatological pathography of James Joyce (1882-1941)]
    L Ventura
    U O C Anatomia Patologica, ASL 4 L Aquila, Ospedale San Salvatore, Coppito, L Aquila, Italy
    Reumatismo 60:150-8. 2008
    ..Severe eye problems, caused by recurrent iritis attacks even complicated by glaucoma and cataracts, led him almost to blindness...
  93. ncbi Management of patient with Cogan's syndrome: a case report
    Tatjana Ziu
    Department of Ophthalmology, Hospital Centre of Elbasan, Albany
    Oftalmologia 54:73-5. 2010
    ..Cogan syndrome-CS, is a rare autoimmune disease defined as an inflammation of the eyes followed by bilateral audiovestibular symptoms...
  94. ncbi Oculomucosal and gastrointestinal involvement in Epstein-Barr virus-associated hydroa vacciniforme
    Takenobu Yamamoto
    Department of Dermatology, Okayama Graduate School of Medicine, Okayama, Japan
    Eur J Dermatol 22:380-3. 2012
    ..8%) had ocular symptoms including iritis, conjunctival hyperemia and corneal erosions, and 2 patients (3...
  95. ncbi Juvenile idiopathic arthritis
    Maria Espinosa
    The Steven and Alexandra Cohen Children s Medical Center of New York, North Shore Long Island Jewish Health System, New Hyde Park, NY, USA
    Pediatr Rev 33:303-13. 2012
    ..Genetic analysis also may allow physicians to target therapies more effectively. It is hoped that development of more specific therapies will decrease overall immunosuppression and other associated toxicities...
  96. pmc The comparison of fluoroquinolones to nonfluoroquinolone antibacterial agents for the prevention of endophthalmitis in a rabbit model
    Regis P Kowalski
    The Charles T Campbell Ophthalmic Microbiology Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Ocul Pharmacol Ther 28:604-8. 2012
    ..We hypothesize that FQ anti-infectives are more effective than non-FQ antibacterial agents for preventing endophthalmitis...
  97. ncbi Similarity between chronic reactive arthritis and ankylosing spondylitis.A 32-35-year follow-up study
    K Kaarela
    Rheumatism Foundation Hospital, Heinola, Finland
    Clin Exp Rheumatol 27:325-8. 2009
    ..We assessed the long-term outcome of recent reactive arthritis (ReA) during 1973-2007 and ankylosing spondylitis (AS) during 1973-1997 to identify similarities in manifestations of disease...
  98. ncbi Extracranial carotid artery aneurysm due to Behcet's disease
    Sebnem Albeyoglu
    Department of Cardiovascular Surgery, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Center, Istanbul, Turkey
    Asian Cardiovasc Thorac Ann 18:574-6. 2010
    Behçet's disease is a chronic systemic inflammatory disorder associated with recurrent oral and genital ulcers and iritis. Vascular lesions are encountered in 7%-29% of patients, gravely affecting the course of the disease...
  99. ncbi Prevalence of ossification of posterior longitudinal ligament in patients with ankylosing spondylitis
    Tae Jong Kim
    Department of Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University College of Medicine, Seoul, Republic of Korea
    J Rheumatol 34:2460-2. 2007
    ..To determine the prevalence of ossification of the posterior longitudinal ligament (OPLL) in patients with ankylosing spondylitis (AS)...
  100. ncbi Ophthalmological aspects of IBD
    C Manganelli
    Department of Ophthalmology, Catholic University of the Sacred Heart, Rome, Italy
    Eur Rev Med Pharmacol Sci 13:11-3. 2009
    Ocular manifestations occur in 4-12% of patients with IBD. Uveitis and iritis are more frequently associated with ulcerative colitis while episcleritis is more common in Crohn's disease...
  101. ncbi Extradigestive manifestations of IBD in pediatrics
    M Aloi
    Pediatric Gastroenterology and Hepatology Unit, Department of Pediatrics, University La Sapienza, Rome, Italy
    Eur Rev Med Pharmacol Sci 13:23-32. 2009
    ..e., pyoderma gangrenosum, anterior uveitis/iritis, ankylosing spondylitis, primary sclerosing cholangitis)...

Research Grants19

  1. ENDOTOXIN INDUCED UVEITIS
    James Rosenbaum; Fiscal Year: 2000
    ..uveitis in transgenic HLA-B27 rats will permit studies on the relationship between HLA-B27, gram negative bacteria, and iritis. When taken together, the specific aims are designed to help clarify the pathogenesis of the anterior uveitis.
  2. IONTOPHORESIS OF ARA-AMP TO HERPES VIRUS LESIONS
    James Hill; Fiscal Year: 1980
    ..therapeutic efficacy of iontophoretic application of Ara-AMP, Ara-T, Ara-TMP, and ACG for the treatment of HSV-1 iritis (uveitis) in rabbit eyes...
  3. HERPES EYE DISEASE
    Roy Beck; Fiscal Year: 2000
    ..placebo for 1) prevention or delay of recurrences (HEDS-APT) and 2) prevention or delay of stromal keratitis or iritis subsequent to epithelial keratitis (HEDS-EKT)...
  4. FOUR DIMENSIONAL IMAGING OF THE IMMUNE RESPONSE IN VIVO
    James T Rosenbaum; Fiscal Year: 2010
    ..These studies should result in a fundamental improvement in the understanding of how T cells behave within a site of inflammation. ..
  5. UVEITIS GENE-EXPRESSION PROFILING
    James Rosenbaum; Fiscal Year: 2008
    ..The creation of a gene expression data base for patients with uveitis has the potential to clarify the pathogenesis of disease, establish new diagnostic tools, and provide a means for predicting prognosis. ..
  6. Endotoxin-induced Uveitis Revisited
    James T Rosenbaum; Fiscal Year: 2010
    ..Future studies can buil d on these observations to test anti-inflammtory molecules induced by endotoxin as these molecules are potentially useful in the treatment of uveitis and other inflammations. ..
  7. Iron Deficiency and Anemia in HIV and HCV-Infected Women
    Richard Semba; Fiscal Year: 2005
    ..S. and elsewhere. ..
  8. Hepcidin and the pathogenesis of anemia in older adults.
    Richard D Semba; Fiscal Year: 2010
    ..This study should provide new insight into the epidemiology and biological mechanisms of anemia among older adults and help identify strategies aimed at the prevention and treatment of anemia. ..
  9. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
    ..The relationship between mastitis and breastmilk HIV load and the epidemiology and microbiology of mastitis will be examined in a new cohort of HIV-infected lactating women. ..
  10. OCULAR HERPES SIMPLEX
    Herbert Kaufman; Fiscal Year: 2008
    ..acyclovir and trifluridine to determine its efficacy in models of epithelial keratitis, stromal keratitis, and iritis and to determine if BAY 57-1293 can prevent recurrences of herpes when administered both topically and ..
  11. CHEMOTACTIC FACTORS IN ANIMAL MODELS OF UVEITIS
    James Rosenbaum; Fiscal Year: 2008
    ..We believe that these aims are novel, innovative, especially suited to the skills and achievements demonstrated by our laboratory, and highly relevant to clarifying the pathogenesis of anterior uveitis. ..
  12. CORE GRANT FOR VISION RESEARCH
    Herbert Kaufman; Fiscal Year: 2008
    ..This Core Grant has [unreadable] been a vital force in keeping vision research highly active at LSU for the past 25 years, and we hope that it will continue to serve this function in the future. [unreadable] [unreadable]..
  13. ADJUNCT VITAMIN A THERAPY FOR TUBERCULOSIS AND HIV/AIDS
    Richard Semba; Fiscal Year: 2005
    ....
  14. Anterior Uveal Dendritic Cells
    James Rosenbaum; Fiscal Year: 2004
    ..These studies will clarify the function of the immune system within the eye and may suggest novel therapeutic approaches in the treatment of uveitis. ..
  15. VITAMIN A SUPPLEMENTATION FOR HIV INFECTED CHILDREN
    Richard Semba; Fiscal Year: 2002
    ....
  16. IMMUNOLOGY/MOLECULAR BIOLOGY TRAINING IN OPHTHALMOLOGY
    James Rosenbaum; Fiscal Year: 2007
    ..The quality of the institution, the talents of the specific faculty, the abilities of the applicant pool, and the proven success of the program areadditional strengths of this application. ..
  17. Oxidative Stress and the Pathogenesis of Sarcopenia and Disability in Older Women
    Richard Semba; Fiscal Year: 2008
    ..AGEs are a potentially modifiable risk factor, as circulating AGEs can be lowered by dietary modification and by pharmacological intervention. ..
  18. Ophthalmic Antibiotic Resistance Study
    Kirk Wilhelmus; Fiscal Year: 2003
    ..abstract_text> ..
  19. OCULAR INFECTION WITH THE HERPES VIRUSES
    TODD MARGOLIS; Fiscal Year: 2003
    ..Taken together, these studies will begin to elucidate mechanisms by which neurons survive HSV infection to become reservoirs of latent virus responsible for recurrent disease. ..