retinal perforations

Summary

Summary: Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes.

Top Publications

  1. ncbi Photoreceptor inner/outer segment defect imaging by spectral domain OCT and visual prognosis after macular hole surgery
    Jaeryung Oh
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, Florida
    Invest Ophthalmol Vis Sci 51:1651-8. 2010
  2. ncbi Postoperative complications associated with 25-gauge pars plana vitrectomy
    Omesh P I Gupta
    Retina Service, Wills Eye at Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmic Surg Lasers Imaging 38:270-5. 2007
  3. pmc Population-based incidence of macular holes
    Colin A McCannel
    Jules Stein Eye Institute, Department of Ophthalmology, UCLA David Geffen School of Medicine, Los Angeles, California 90095, USA
    Ophthalmology 116:1366-9. 2009
  4. ncbi Anatomical outcomes of surgery for idiopathic macular hole as determined by optical coherence tomography
    Michael S Ip
    Department of Ophthalmology, University of Wisconsin, Clinical Science Center, F4 336, 600 Highland Ave, Madison, WI 53792, USA
    Arch Ophthalmol 120:29-35. 2002
  5. pmc Vitrectomy and gas for inferior break retinal detachments: are the results comparable to vitrectomy, gas, and scleral buckle?
    L Wickham
    Western Eye Hospital, Marylebone Road, London NW1 5YE, UK
    Br J Ophthalmol 88:1376-9. 2004
  6. pmc High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography
    Vivek J Srinivasan
    Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Ophthalmology 113:2054.e1-14. 2006
  7. ncbi Tears of the retinal pigment epithelium: an old problem in a new era
    Louis K Chang
    Jules Stein Eye Institute, Department of Ophthalmology, University of California Los Angeles, 100 Stein Plaza, Los Angeles, CA 90095, USA
    Retina 27:523-34. 2007
  8. ncbi Value of internal limiting membrane peeling in surgery for idiopathic macular hole and the correlation between function and retinal morphology
    Ulrik Correll Christensen
    Department of Ophthalmology, Glostrup Hospital, Glostrup, Denmark
    Acta Ophthalmol 87:1-23. 2009
  9. ncbi Correlation of visual recovery and presence of photoreceptor inner/outer segment junction in optical coherence images after successful macular hole repair
    Takayuki Baba
    Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan
    Retina 28:453-8. 2008
  10. pmc 25-gauge vs 20-gauge system for pars plana vitrectomy: a prospective randomised clinical trial
    Lukas Kellner
    Department of Ophthalmology, Rudolph Foundation Clinic, Vienna, Austria
    Br J Ophthalmol 91:945-8. 2007

Research Grants

  1. New Tool to Study Neurochemical Modulation of Feeding
    SCOTT SHIPPY; Fiscal Year: 2005
  2. In Vivo Sampling to Study the Neurobiology of Gluacoma
    SCOTT SHIPPY; Fiscal Year: 2005
  3. Control of Eye Melanoma Metastasis
    Hans Grossniklaus; Fiscal Year: 2003
  4. SUBMACULAR SURGERY TRIALS PATHOLOGY CENTER
    Hans Grossniklaus; Fiscal Year: 2003
  5. Eye Disease in Cuban-American and Puerto Rican Adults
    Ingrid Scott; Fiscal Year: 2003
  6. Control of Eye Melanoma Metastsis
    Hans E Grossniklaus; Fiscal Year: 2010

Detail Information

Publications268 found, 100 shown here

  1. ncbi Photoreceptor inner/outer segment defect imaging by spectral domain OCT and visual prognosis after macular hole surgery
    Jaeryung Oh
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, Florida
    Invest Ophthalmol Vis Sci 51:1651-8. 2010
    ..To evaluate photoreceptor inner/outer segment (IS/OS) defect parameters by using spectral domain-optical coherence tomography (SD-OCT) for correlation with visual outcomes in macular hole surgery (MHS)...
  2. ncbi Postoperative complications associated with 25-gauge pars plana vitrectomy
    Omesh P I Gupta
    Retina Service, Wills Eye at Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmic Surg Lasers Imaging 38:270-5. 2007
    ..To report postoperative complications in eyes undergoing 25-gauge pars plana vitrectomy (PPV)...
  3. pmc Population-based incidence of macular holes
    Colin A McCannel
    Jules Stein Eye Institute, Department of Ophthalmology, UCLA David Geffen School of Medicine, Los Angeles, California 90095, USA
    Ophthalmology 116:1366-9. 2009
    ..To determine the incidence of full-thickness macular holes in Olmsted County, Minnesota...
  4. ncbi Anatomical outcomes of surgery for idiopathic macular hole as determined by optical coherence tomography
    Michael S Ip
    Department of Ophthalmology, University of Wisconsin, Clinical Science Center, F4 336, 600 Highland Ave, Madison, WI 53792, USA
    Arch Ophthalmol 120:29-35. 2002
    ....
  5. pmc Vitrectomy and gas for inferior break retinal detachments: are the results comparable to vitrectomy, gas, and scleral buckle?
    L Wickham
    Western Eye Hospital, Marylebone Road, London NW1 5YE, UK
    Br J Ophthalmol 88:1376-9. 2004
    ..To compare the success rates of vitrectomy and gas with vitrectomy, gas, and buckle in the treatment of inferior break retinal detachments...
  6. pmc High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography
    Vivek J Srinivasan
    Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Ophthalmology 113:2054.e1-14. 2006
    ..To assess high-speed ultrahigh-resolution optical coherence tomography (OCT) image resolution, acquisition speed, image quality, and retinal coverage for the visualization of macular pathologies...
  7. ncbi Tears of the retinal pigment epithelium: an old problem in a new era
    Louis K Chang
    Jules Stein Eye Institute, Department of Ophthalmology, University of California Los Angeles, 100 Stein Plaza, Los Angeles, CA 90095, USA
    Retina 27:523-34. 2007
    ..The authors review the clinical features, etiologies, imaging characteristics, and pathogenesis of RPE tears and their relationship with intravitreal anti-VEGF treatments...
  8. ncbi Value of internal limiting membrane peeling in surgery for idiopathic macular hole and the correlation between function and retinal morphology
    Ulrik Correll Christensen
    Department of Ophthalmology, Glostrup Hospital, Glostrup, Denmark
    Acta Ophthalmol 87:1-23. 2009
    ..05% isotonic ICG-assisted ILM peeling in stage 2 macular hole surgery...
  9. ncbi Correlation of visual recovery and presence of photoreceptor inner/outer segment junction in optical coherence images after successful macular hole repair
    Takayuki Baba
    Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan
    Retina 28:453-8. 2008
    ....
  10. pmc 25-gauge vs 20-gauge system for pars plana vitrectomy: a prospective randomised clinical trial
    Lukas Kellner
    Department of Ophthalmology, Rudolph Foundation Clinic, Vienna, Austria
    Br J Ophthalmol 91:945-8. 2007
    ..To compare 25-gauge vs 20-gauge system for pars plana vitrectomy in a prospective, randomised, controlled clinical trial...
  11. pmc Phacovitrectomy without prone posture for full thickness macular holes
    P R Simcock
    West of England Eye Unit, Royal Devon and Exeter Hospital Wonford, Barrack Road, Exeter EX2 5DW, UK
    Br J Ophthalmol 85:1316-9. 2001
    ..To investigate the role of phacovitrectomy surgery without prone posture for stage 2 and 3 macular holes...
  12. ncbi Clinical evaluation of the use of indocyanine green for peeling the internal limiting membrane in macular hole surgery
    Aude Husson-Danan
    Centre Hospitalier National d Ophtalmologie des Quinze Vingts, 28 rue de Charenton, 75012 Paris, France
    Graefes Arch Clin Exp Ophthalmol 244:291-7. 2006
    ..To evaluate the role of indocyanine green (infracyanine) in macular hole surgery...
  13. ncbi Proinflammatory cytokines and angiogenic and anti-angiogenic factors in vitreous of patients with proliferative diabetic retinopathy and eales' disease
    Ponnalagu Murugeswari
    Department of Immunology, Dr G Venkataswamy Eye Research Institute, Aravind Medical Research Foundation, Tamilnadu, India
    Retina 28:817-24. 2008
    ....
  14. ncbi Diagnosis of macular pseudoholes and lamellar macular holes by optical coherence tomography
    Belkacem Haouchine
    Department of Ophthalmology, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Universite, Paris, France
    Am J Ophthalmol 138:732-9. 2004
    ..To assess the usefulness of optical coherence tomography (OCT) for better differential diagnosis of macular pseudoholes (MPH) and lamellar macular holes (LMH)...
  15. ncbi Prediction of postoperative visual outcome based on hole configuration by optical coherence tomography in eyes with idiopathic macular holes
    Sentaro Kusuhara
    Department of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan
    Am J Ophthalmol 138:709-16. 2004
    ..To evaluate whether an index based on hole configuration can be used to predict visual outcome in eyes with idiopathic macular holes...
  16. pmc Visual quality of life after macular hole surgery: outcome and predictive factors
    Christoph Hirneiss
    Department of Ophthalmology, Ludwig Maximilians University, Mathildenstr 8, 80336 Munich
    Br J Ophthalmol 91:481-4. 2007
    ..In the present study we evaluated the functional success after macular hole surgery in correlation to visual quality of life and looked for predictive factors determining surgical success...
  17. ncbi Brilliant blue G selectively stains the internal limiting membrane/brilliant blue G-assisted membrane peeling
    Hiroshi Enaida
    Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Retina 26:631-6. 2006
    ..To report the use of the dye brilliant blue G (BBG) for staining of the internal limiting membrane (ILM) during macular hole (MH) and epiretinal membrane (ERM) surgery...
  18. ncbi A novel segmentation algorithm for volumetric analysis of macular hole boundaries identified with optical coherence tomography
    David Xu
    Ophthalmic Imaging Center, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Invest Ophthalmol Vis Sci 54:163-9. 2013
    ..To demonstrate a novel algorithm for macular hole (MH) segmentation and volumetric analysis...
  19. ncbi Value of internal limiting membrane peeling in surgery for idiopathic macular hole stage 2 and 3: a randomised clinical trial
    U C Christensen
    Department of Ophthalmology, Glostrup Hospital, Nordre Ringvej 57, DK 2600 Glostrup, Denmark
    Br J Ophthalmol 93:1005-15. 2009
    ..To determine the effect of internal limiting membrane (ILM) peeling on anatomical and functional success rates in stage 2 and 3 idiopathic macular hole surgery (MHS)...
  20. ncbi Prevalence of full-thickness macular holes in urban and rural adult Chinese: the Beijing Eye Study
    Shuang Wang
    Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
    Am J Ophthalmol 141:589-91. 2006
    ..To determine the prevalence of full-thickness macular holes in the elderly Chinese population...
  21. ncbi Clinical course of macular holes: the Eye Disease Case-Control Study
    E Y Chew
    Division of Biometry and Epidemiology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892 2510, USA
    Arch Ophthalmol 117:242-6. 1999
    ..To describe the clinical course of affected and unaffected eyes in patients with idiopathic macular holes...
  22. ncbi Management of inferior breaks in pseudophakic rhegmatogenous retinal detachment with pars plana vitrectomy and air
    Vicente Martinez-Castillo
    Vall d Hebron Hospital, Universidad Autonoma de Barcelona, Calle Londres No 54, 41B, Barcelona 08036, Spain
    Arch Ophthalmol 123:1078-81. 2005
    ..To determine the role of pars plana vitrectomy without scleral buckling and air as a tamponade with 24 hours of prone positioning in the management of inferior breaks in primary pseudophakic rhegmatogenous retinal detachment...
  23. ncbi Optical coherence tomography predictive factors for macular hole surgery outcome
    J M Ruiz-Moreno
    Albacete Medical School, University of Castilla La Mancha, Albacete, Spain
    Br J Ophthalmol 92:640-4. 2008
    ..To evaluate the use of preoperative optical coherence tomography (OCT) findings as predictive factors for macular hole (MH) surgery outcomes...
  24. ncbi Prevalence of idiopathic macular hole in adult rural and urban south Indian population
    Parveen Sen
    Bhagwan Mahavir Vitreo Retinal Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India
    Clin Experiment Ophthalmol 36:257-60. 2008
    ..This study was undertaken to evaluate the prevalence of idiopathic macular hole in a defined community in Southern India...
  25. ncbi Retinal detachment associated with macular hole in high myopia: using the vitreous anatomy to optimize the surgical approach
    Guido Ripandelli
    Fondazione G B Bietti per lo Studio e la Ricerca in Oftalmologia, Via Pasubio 6, 00195 Rome, Italy
    Ophthalmology 111:726-31. 2004
    ..To evaluate the efficacy of different surgical strategies on the postoperative outcomes of retinal detachments (RDs) associated with macular holes (MHs) in high myopia...
  26. ncbi Subfoveal liquid perfluorocarbon
    Guido Lesnoni
    Policlinico Città di Pomezia, Unità Operativa di Chirurgia Oculistica, Unità Operativa di Chirurgia Vitreoretinica, Rome, Italy
    Retina 24:172-6. 2004
  27. ncbi Correlation between foveal structure and visual outcome following macular hole surgery: a spectral optical coherence tomography study
    Zofia Michalewska
    Klinika Okulistyczna Jasne Blonia, ul Rojna 90, Lodz 91 162, Poland
    Graefes Arch Clin Exp Ophthalmol 246:823-30. 2008
    ....
  28. pmc Relationship between macular hole size and the potential benefit of internal limiting membrane peeling
    R Tadayoni
    Service d Ophtalmologie, Hopital Lariboisiere, 2, rue Ambroise Pare, Paris, France
    Br J Ophthalmol 90:1239-41. 2006
    ..To investigate the relationship between the size of macular holes and the possible benefit of internal limiting membrane (ILM) peeling...
  29. ncbi Pars plana vitrectomy alone for the management of inferior breaks in pseudophakic retinal detachment without facedown position
    Vicente Martinez-Castillo
    Vall d Hebron Hospital, Universidad Autonoma de Barcelona, Barcelona, Spain
    Ophthalmology 112:1222-6. 2005
    ..To introduce a new approach with pars plana vitrectomy (PPV) alone and no facedown positioning in the management of pseudophakic retinal detachments (RDs) with inferior breaks...
  30. pmc Management of primary rhegmatogenous retinal detachment with inferior breaks
    A Sharma
    Department of Ophthalmology, St Thomas s Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Br J Ophthalmol 88:1372-5. 2004
    ..Following a recent pilot study showing that such cases can be safely treated by PPV without SB the authors re-examined their management of RRD in which inferior breaks were present...
  31. ncbi Three-dimensional imaging of macular holes with high-speed optical coherence tomography
    Masanori Hangai
    Department of Ophthalmology and Visual Science, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Ophthalmology 114:763-73. 2007
    ..To demonstrate the advantages of 3-dimensional imaging of macular hole pathology using new-generation high-speed optical coherence tomography (OCT)...
  32. ncbi Macular holes: classification, epidemiology, natural history and treatment
    Morten la Cour
    Eye Department, Rigshospitalet, Copenhagen, Denmark
    Acta Ophthalmol Scand 80:579-87. 2002
    ..If the posterior vitreous is attached, the risk is approximately 15%. If an impending hole is found in the other eye, the risk rises to 50%...
  33. ncbi Mathematical analysis of specific anatomic foveal configurations predisposing to the formation of macular holes
    Yoreh Barak
    Department of Ophthalmology and Visual Sciences, University of Louisville, Kentucky, USA
    Invest Ophthalmol Vis Sci 52:8266-70. 2011
    ..To mathematically analyze and to clinically describe specific anatomic foveal configurations predisposing to the formation of macular holes in comparison with normal foveal anatomy...
  34. ncbi Photoreceptor damage and foveal sensitivity in surgically closed macular holes: an adaptive optics scanning laser ophthalmoscopy study
    Sotaro Ooto
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Am J Ophthalmol 154:174-186.e2. 2012
    ....
  35. ncbi Macular hole surgery and cataract extraction: combined vs consecutive surgery
    Aurore Muselier
    Department of Ophthalmology University Hospital, rue du Faubourg Raines, Dijon, France
    Am J Ophthalmol 150:387-91. 2010
    ..To compare the functional and the anatomic outcomes of a combined surgery and consecutive surgery for macular hole and cataract extraction...
  36. ncbi Lamellar macular hole: a clinicopathologic correlation of surgically excised epiretinal membranes
    Barbara Parolini
    Department of Ophthalmology, Ospedale Sacrocuore Don Calabria, Negrar, Verona, Italy
    Invest Ophthalmol Vis Sci 52:9074-83. 2011
    ..To correlate clinical and optical coherence tomographic (OCT) features with morphologic and immunohistochemical findings of epiretinal membranes (ERMs) in lamellar macular holes (LMHs)...
  37. ncbi Macular hole surgery prognostic success rates based on macular hole size
    Amanda B Salter
    Department of Ophthalmology, New York University Medical Center, New York, New York, USA
    Ophthalmic Surg Lasers Imaging 43:184-9. 2012
    ..To evaluate the correlation between macular hole (MH) surgery outcomes and preoperative factors believed to affect surgical success rates...
  38. ncbi Idiopathic full-thickness macular holes and the vitreomacular interface: a high-resolution spectral-domain optical coherence tomography study
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
    Am J Ophthalmol 154:881-892.e2. 2012
    ..To analyze the vitreomacular interface in idiopathic full-thickness macular holes (MHs) using spectral-domain optical coherence tomography...
  39. ncbi The natural history of lamellar macular holes: a spectral domain optical coherence tomography study
    Ferdinando Bottoni
    Eye Clinic, Department of Clinical Science Luigi Sacco, Sacco Hospital, University of Milan, Via Andrea Verga 8, 20144, Milano, Italy
    Graefes Arch Clin Exp Ophthalmol 251:467-75. 2013
    ..To study the evolution of lamellar macular holes (LMHs) using spectral domain-optical coherence tomography (SD-OCT)...
  40. ncbi A comparison of several methods of macular hole measurement using optical coherence tomography, and their value in predicting anatomical and visual outcomes
    Laura Wakely
    Calderdale Royal Hospital, Salterhebble Hill, Halifax, UK
    Br J Ophthalmol 96:1003-7. 2012
    ..To compare several methods of macular hole measurement using optical coherence tomography (OCT), and to assess their predictive capability against anatomical and visual outcomes in a single cohort of patients...
  41. ncbi The 1-year incidence of rhegmatogenous retinal detachment post 23-gauge pars plana vitrectomy
    Mahta Rasouli
    Department of Ophthalmology, University of Alberta, Edmonton, Alta
    Can J Ophthalmol 47:262-3. 2012
    ..The purpose of this study was to evaluate the 1-year incidence of retinal tear or retinal detachment following 23-gauge pars plana vitrectomy (PPV) for epiretinal membrane (ERM), macular hole (MH), or vitreomacular traction (VMT)...
  42. ncbi United Kingdom National Ophthalmology Database study of vitreoretinal surgery: report 2, macular hole
    Timothy L Jackson
    King s College London, London, United Kingdom
    Ophthalmology 120:629-34. 2013
    ..To study macular hole (MH) surgery in terms of baseline demographics, intraoperative complications, post-vitrectomy cataract, reoperation, and visual outcome...
  43. pmc Decreased retinal sensitivity after internal limiting membrane peeling for macular hole surgery
    Ramin Tadayoni
    Service d Ophtalmologie, Hopital Lariboisiere, 2, rue Ambroise Pare, Paris 75010, France
    Br J Ophthalmol 96:1513-6. 2012
    ....
  44. ncbi Use of heavy Trypan blue in macular hole surgery
    S Y Lesnik Oberstein
    Department of Ophthalmology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Eye (Lond) 24:1177-81. 2010
    ..Heavy Trypan blue eliminates the need for an air-fluid exchange (AFX) and appears to have little retinal toxicity. This study refers to a prospective, consecutive trial with heavy Trypan blue in macular hole surgery...
  45. ncbi Macular hole surgery with and without indocyanine green assistance
    K Slaughter
    Ophthalmology Department, Royal Brisbane Hospital, Herston, Queensland, Australia
    Eye (Lond) 18:376-8. 2004
    ..To compare the results of macular hole surgery with the use of indocyanine green (ICG) to assist internal limiting membrane (ILM) peeling and macular hole surgery without indocyanine green use...
  46. ncbi Retinal pigment epithelial tears after intravitreal bevacizumab injection for predominantly classic choroidal neovascularization
    L Arias
    Department of Ophthalmology, Bellvitge University Hospital, L Hospitalet de Llobregat, Barcelona, Spain
    Eur J Ophthalmol 17:992-5. 2007
    ..To detect retinal pigment epithelium (RPE) tears in predominantly classic choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) treated with intravitreal bevacizumab injections...
  47. ncbi Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial
    Noemi Lois
    Ophthalmology Department, Grampian University Hospitals NHS National Health Service Trust, Aberdeen, United Kingdom
    Invest Ophthalmol Vis Sci 52:1586-92. 2011
    ..To determine whether internal limiting membrane (ILM) peeling is effective and cost effective compared with no peeling in patients with idiopathic stage 2 or 3 full-thickness maculay hole (FTMH)...
  48. ncbi Microperimetric determination of retinal sensitivity in areas of dissociated optic nerve fiber layer following internal limiting membrane peeling
    Hiroki Imai
    Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan
    Jpn J Ophthalmol 54:435-40. 2010
    ..To investigate the effects of a dissociated optic nerve fiber layer (DONFL) on retinal sensitivity...
  49. ncbi The dynamic healing process of idiopathic macular holes after surgical repair: a spectral-domain optical coherence tomography study
    Ferdinando Bottoni
    Eye Clinic, Department of Clinical Science Luigi Sacco, Sacco Hospital, University of Milan, Milan, Italy
    Invest Ophthalmol Vis Sci 52:4439-46. 2011
    ..To analyze progressive changes of the outer retina after vitrectomy for macular hole (MH) repair...
  50. ncbi Internal limiting membrane peeling with indocyanine green or trypan blue in macular hole surgery: a randomized trial
    Julia Beutel
    University Eye Clinic, University Hospital Schleswig Holstein, Campus Lubeck, University at Lubeck, Lubeck, Germany
    Arch Ophthalmol 125:326-32. 2007
    ..To report on anatomical and visual outcomes after vitrectomy and internal limiting membrane peeling for idiopathic macular hole repair...
  51. ncbi Relationship of dissociated optic nerve fiber layer appearance to internal limiting membrane peeling
    Yoshinori Mitamura
    Department of Ophthalmology, School of Medicine, Sapporo Medical University, Sapporo, Japan
    Ophthalmology 112:1766-70. 2005
    ..We studied the relation between the DONFL appearance and internal limiting membrane (ILM) peeling and performed static microperimetry to explore the possible mechanisms underlying the DONFL appearance...
  52. ncbi Dyes in ocular surgery: principles for use in chromovitrectomy
    Michel Eid Farah
    Vision Institute, Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
    Am J Ophthalmol 148:332-40. 2009
    ..To present the current state-of-the-art information regarding the properties, indications, surgical techniques, and toxic effects of current and past applications of vital dyes in chromovitrectomy...
  53. ncbi Long-term follow-up after macular hole surgery with internal limiting membrane peeling
    Christos Haritoglou
    Department of Ophthalmology, Ludwig Maximilians University, Munich, Germany
    Am J Ophthalmol 134:661-6. 2002
    ..To report long-term anatomical and functional results after pars plana vitrectomy with peeling of the internal limiting membrane (ILM) for idiopathic macular hole...
  54. ncbi Improvements in the understanding and treatment of macular hole
    Mark W Johnson
    W K Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan School of Medicine, Ann Arbor, Michigan 48105, USA
    Curr Opin Ophthalmol 13:152-60. 2002
    ....
  55. ncbi Can the risk of retinal pigment epithelium tears after bevacizumab treatment be predicted? An optical coherence tomography study
    M Leitritz
    Department of Ophthalmology, University Eye Hospital, Tuebingen, Germany
    Eye (Lond) 22:1504-7. 2008
    ..The purpose of this study was to evaluate whether simple measurements of optical coherence tomography (OCT) can predict the individual risk of an RPE tear in preoperative candidates...
  56. ncbi Retinal pigment epithelial tears in ranibizumab-treated eyes
    Bradley T Smith
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    Retina 29:335-9. 2009
    ..To report the incidence of retinal pigment epithelial (RPE) tears in patients treated with ranibizumab therapy for choroidal neovascularization due to age-related macular degeneration...
  57. ncbi Management of macular holes: a comparison of 1-year outcomes of 3 surgical techniques
    Shlomit Schaal
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Retina 29:1091-6. 2009
    ..To evaluate the contribution of internal limiting membrane (ILM) peeling with and without indocyanine green (ICG) to hole closure and functional results in patients with idiopathic macular hole...
  58. pmc Types of macular hole closure and their clinical implications
    S W Kang
    Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Br J Ophthalmol 87:1015-9. 2003
    ..To evaluate the clinical significance of macular hole closure types assessed by optical coherence tomography (OCT)...
  59. ncbi Foveal pseudocyst as the first step in macular hole formation: a prospective study by optical coherence tomography
    B Haouchine
    Department of Ophthalmology, , , , France
    Ophthalmology 108:15-22. 2001
    ..Foveal pseudocyst formation may be the result of the incomplete separation of the vitreous cortex at the foveal center and the particular structure of the foveal Müller cells...
  60. ncbi Pathogenesis of macular holes and therapeutic implications
    William E Smiddy
    Department of Ophthalmology, University of Miami School of Medicine, Bascom Palmer Eye Institute, Miami, Florida 33101, USA
    Am J Ophthalmol 137:525-37. 2004
    ..To review the literature and identify consistencies and inconsistencies in existing theories of pathogenesis and to consider some of their possible therapeutic implications...
  61. ncbi Intraoperative sclerotomy-related retinal breaks for macular surgery, 20- vs 25-gauge vitrectomy systems
    Richard Scartozzi
    Retina Service, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, USA
    Am J Ophthalmol 143:155-6. 2007
    ..To compare the rate of intraoperative sclerotomy-related retinal breaks (SRRB) between 20- and 25-gauge vitrectomy systems for the correction of macular pucker (MP) and macular hole (MH)...
  62. ncbi Disruption of the photoreceptor inner segment-outer segment junction in eyes with macular holes
    Louis K Chang
    Vitreous, Retina, Macula Consultants of New York, and the LuEsther T Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York, USA
    Retina 28:969-75. 2008
    ..To examine the relationship between visual acuity and morphologic characteristics of macular holes as determined using spectral domain optical coherence tomography (SD OCT)...
  63. ncbi An in vivo evaluation of Brilliant Blue G in animals and humans
    M Remy
    Department of Ophthalmology, Ludwig Maximilians University, Mathildenstr 8, 80336 Munich, Germany
    Br J Ophthalmol 92:1142-7. 2008
    ..To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining properties in humans...
  64. ncbi Foveal anatomic changes in a progressing stage 1 macular hole documented by spectral-domain optical coherence tomography
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
    Ophthalmology 117:806-10. 2010
    ..To report the case of a stage 1 macular hole and the sequential intrafoveal changes with spectral-domain optical coherence tomography (SD-OCT)...
  65. ncbi Prevalence and characteristics of foveal retinal detachment without macular hole in high myopia
    Takayuki Baba
    Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Am J Ophthalmol 135:338-42. 2003
    ....
  66. ncbi Traumatic macular hole: observations, pathogenesis, and results of vitrectomy surgery
    R N Johnson
    Retina Research Fund of St. Mary's Medical Center, San Francisco, California 94109, USA
    Ophthalmology 108:853-7. 2001
    ..The visual acuity improved two or more lines in 21 (84%) cases, and 16 (64%) achieved 20/50 or better vision. CONCLUSIONS: Vitrectomy surgery can successfully close macular holes associated with trauma and improve vision...
  67. ncbi 23-Gauge versus 20-gauge system for pars plana vitrectomy: a prospective randomised clinical trial
    B Wimpissinger
    Department of Ophthalmology, Rudolph Foundation Clinic, Vienna, Austria
    Br J Ophthalmol 92:1483-7. 2008
    ..To compare the sutureless 23-gauge system with a standard 20-gauge system in pars plana vitrectomy...
  68. ncbi Macular hole formation: new data provided by optical coherence tomography
    A Gaudric
    Department of Ophthalmology, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Universite Paris 7, France
    Arch Ophthalmol 117:744-51. 1999
    ..To establish the sequence of events leading from vitreofoveal traction to full-thickness macular hole formation...
  69. ncbi A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery
    Gildo Y Fujii
    Microsurgery Advanced Design Laboratory, Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Ophthalmology 109:1807-12; discussion 1813. 2002
    ..To introduce and evaluate the infusion and aspiration rates and operative times of the 25-gauge transconjunctival sutureless vitrectomy system (TSV) DESIGN: In vitro experimental and comparative interventional study...
  70. ncbi Retinal detachment due to a macular hole in a patient with Behcet disease treated with vitrectomy and silicone oil tamponade
    I Georgalas
    Department Ophthalmology, G Genimatas General Hospital of Athens, NHS, Athens Greece
    Eur J Ophthalmol 18:1023-4. 2008
    ..A rare case of unilateral retinal detachment due to a macular hole in a patient with Behçet disease is presented...
  71. ncbi Intravitreal injection of microplasmin for treatment of vitreomacular adhesion: results of a prospective, randomized, sham-controlled phase II trial (the MIVI-IIT trial)
    Peter Stalmans
    Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium
    Retina 30:1122-7. 2010
    ..It may be avoided by using enzymatic vitreolysis. The MIVI-IIT (traction) study evaluated the ability of a single or repeated injection of microplasmin to release vitreomacular traction...
  72. ncbi Long-term outcome of idiopathic macular hole surgery
    Marie Passemard
    Department of Ophthalmology, University Hospital, Dijon, France
    Am J Ophthalmol 149:120-6. 2010
    ..To evaluate the role of preoperative macular hole (MH) diameter, cataract surgery, and cystoid macular edema (CME) in the reopening of idiopathic macular hole (IMH) after initially successful surgery...
  73. ncbi Inverted internal limiting membrane flap technique for large macular holes
    Zofia Michalewska
    Klinika Okulistyczna Jasne Blonia, Lodz, Poland
    Ophthalmology 117:2018-25. 2010
    ..Flat-open macular holes are associated with limited visual acuity. This article presents a modification of the standard macular hole surgery to improve functional and anatomic outcomes in patients with large macular holes...
  74. ncbi Internal limiting membrane peeling in macular hole surgery
    W E Smiddy
    Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, Florida, USA
    Ophthalmology 108:1471-6; discussion 1477-8. 2001
    ..To evaluate prospectively the ability to peel epiretinal membranes and to correlate the degree of membrane peeling to anatomic success rates...
  75. ncbi A comparison of brilliant blue G, trypan blue, and indocyanine green dyes to assist internal limiting membrane peeling during macular hole surgery
    Dhananjay Shukla
    Retina Vitreous Service, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India
    Retina 31:2021-5. 2011
    ..To compare surgical outcomes with three dyes, brilliant blue G (BBG), trypan blue (TB) and indocyanine green (ICG), used to facilitate internal limiting membrane peeling during macular hole surgery...
  76. ncbi Risk factors for retention of subretinal perfluorocarbon liquid in vitreoretinal surgery
    Enrique Garcia-Valenzuela
    Emory University Eye Center, Atlanta, Georgia 30322, USA
    Retina 24:746-52. 2004
    ..To analyze factors that may lead to inadvertent subretinal retention of perfluorocarbon liquid (PFCL) after vitreoretinal surgery and compare surgical outcomes and complications associated with these events...
  77. ncbi Incidence of endophthalmitis after 20-gauge vs 23-gauge vs 25-gauge pars plana vitrectomy
    Ingrid U Scott
    Departments of Ophthalmology and Public Health Sciences, Penn State College of Medicine, 500 University Drive, HU19, Hershey, PA 17083 0850, USA
    Graefes Arch Clin Exp Ophthalmol 249:377-80. 2011
    ..To compare endophthalmitis rates after 20-gauge versus 23-gauge versus 25-gauge pars plana vitrectomy (PPV) in 2007-2008, and compare the rates with those of 2005-2006...
  78. ncbi Outcomes of 23- and 25-gauge transconjunctival sutureless vitrectomies for idiopathic macular holes
    S Kusuhara
    Department of Ophthalmology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Hyogo, Japan
    Br J Ophthalmol 92:1261-4. 2008
    ..To assess the outcomes of 23-gauge sutureless transconjunctival vitrectomies (TSV), as compared with 25-gauge TSV in macular hole surgeries...
  79. ncbi Outcome results in macular hole surgery: an evaluation of internal limiting membrane peeling with and without indocyanine green
    Tom G Sheidow
    Department of Ophthalmology, University of Western Ontario, London, Ontario, Canada
    Ophthalmology 110:1697-701. 2003
    ..To evaluate the anatomic closure rate and visual outcome in patients undergoing pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling with and without indocyanine green (ICG) enhancement...
  80. ncbi Indocyanine green-assisted peeling of the retinal internal limiting membrane during vitrectomy surgery for macular hole repair
    A P Da Mata
    Cincinnati Eye Institute, Cincinnati, Ohio 45242, USA
    Ophthalmology 108:1187-92. 2001
    ..Indocyanine green staining of the ILM appears to be a safe and useful adjunct in vitreous surgery for macular hole repair...
  81. ncbi Macular hole in Behcet's disease
    Shwu Jiuan Sheu
    Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 20:558-62. 2004
    ..In this report, we present two cases of macular hole in the worse eye of bilateral cases of Behcet's disease, and discuss the possible mechanisms and management in such cases...
  82. ncbi Optical coherence tomography-measured pigment epithelial detachment height as a predictor for retinal pigment epithelial tears associated with intravitreal bevacizumab injections
    Clement K Chan
    Southern California Desert Retina Consultants, Palm Springs, California 92263, USA
    Retina 30:203-11. 2010
    ....
  83. ncbi Dissociated optic nerve fiber layer appearance after internal limiting membrane peeling for idiopathic macular holes
    Yasuki Ito
    Department of Ophthalmology, Nagoya University School of Medicine, Nagoya, Japan
    Ophthalmology 112:1415-20. 2005
    ..To investigate the characteristics and incidence of a dissociated optic nerve fiber layer (DONFL) appearance in eyes after idiopathic macular hole surgery...
  84. pmc Proliferative diabetic retinopathy and relations among antioxidant activity, oxidative stress, and VEGF in the vitreous body
    Hiroshi Izuta
    Department of Biofunctional Evaluation, Molecular Pharmacology, Gifu Pharmaceutical University, Gifu, Japan
    Mol Vis 16:130-6. 2010
    ..To investigate the relationships among antioxidant activities, oxidative stress, and vascular endothelial growth factor (VEGF) in the vitreous body and serum from proliferative diabetic retinopathy (PDR) patients...
  85. ncbi Müller cell cone, an overlooked part of the anatomy of the fovea centralis: hypotheses concerning its role in the pathogenesis of macular hole and foveomacualr retinoschisis
    J D Gass
    Department of Ophthalmology, Vanderbilt University, Nashville, Tenn 37232 8808, USA
    Arch Ophthalmol 117:821-3. 1999
    ....
  86. ncbi Observation of idiopathic full-thickness macular hole closure in early postoperative period as evaluated by optical coherence tomography
    Hiroaki Sato
    Department of Ophthalmology, Yamagata University School of Medicine, Yamagata, Japan
    Am J Ophthalmol 136:185-7. 2003
    ..To report the optical coherence tomography (OCT)-determined progressive changes in a macular hole (MH) following vitreous surgery with a gas tamponade. Observational case report...
  87. ncbi Prevalence of asymptomatic macular holes in highly myopic eyes
    Andrea Maria Coppè
    Fondazione G B Bietti per l Oftalmologia I R C C S, Rome, Italy
    Ophthalmology 112:2103-9. 2005
    ..To evaluate the presence of macular holes (MHs) in very highly myopic eyes in the absence of visual symptoms...
  88. ncbi Immunocytochemical characterization of macular hole opercula
    E Ezra
    Vitreoretinal Unit, Moorfields Eye Hospital, City Road, London EC1V 2PD, England
    Arch Ophthalmol 119:223-31. 2001
    ..To immunocytochemically characterize the neural and glial elements of idiopathic full-thickness macular hole (FTMH) opercula excised during vitrectomy, and to correlate them with the outcome of surgery...
  89. ncbi Combined phacoemulsification and pars plana vitrectomy for macular hole treatment
    Ioannis P Theocharis
    Department of Ophthalmology, University Hospital, Uppsala, Sweden
    Acta Ophthalmol Scand 83:172-5. 2005
    ..To assess the outcome of simultaneous phacoemulsification, pars plana vitrectomy and intraocular lens (IOL) implantation in eyes with macular hole...
  90. ncbi 25-Gauge sutureless vitrectomy versus 20-gauge vitrectomy for the repair of primary rhegmatogenous retinal detachment
    Manfred A Von Fricken
    Retina Group of Washington, Fairfax, Virginia, USA
    Retina 29:444-50. 2009
    ..To compare the anatomic and visual results and complications of 25-gauge transconjunctival sutureless vitrectomy versus conventional 20-gauge vitrectomy for the management of primary rhegmatogenous retinal detachment...
  91. ncbi Watzke-Allen slit beam test in macular holes confirmed by optical coherence tomography
    V Tanner
    Vitreo Retinal Unit, Department of Ophthalmology, 9th Floor, North Wing, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, England
    Arch Ophthalmol 118:1059-63. 2000
    ..To examine the role, validity, and interpretation of Watzke-Allen slit beam testing in patients with idiopathic senile macular holes...
  92. ncbi Outcome of ICG-assisted ILM peel in macular hole surgery
    J Lochhead
    Oxford Eye Hospital, Radcliffe Infirmary, Woodstock Road, UK
    Eye (Lond) 18:804-8. 2004
    ..To investigate whether indocyanine green (ICG) staining of the internal limiting membrane (ILM) improves surgical outcome...
  93. ncbi Indocyanine green staining and removal of internal limiting membrane in macular hole surgery: histology and outcome
    Christos Haritoglou
    Am J Ophthalmol 133:587-8; author reply 588. 2002
  94. pmc The effect of internal limiting membrane removal and indocyanine green on the success of macular hole surgery
    John T Thompson
    Retina Specialists, Greater Baltimore Medical Center, Baltimore, Maryland, USA
    Trans Am Ophthalmol Soc 105:198-205; discussion 205-6. 2007
    ..To compare the anatomic and functional results of 3 different epimacular dissection techniques on macular hole surgery...
  95. ncbi Histology of the vitreoretinal interface after staining of the internal limiting membrane using glucose 5% diluted indocyanine and infracyanine green
    Christos Haritoglou
    Department of Ophthalmology, Ludwig Maximilians University, Munich, Germany
    Am J Ophthalmol 137:345-8. 2004
    ..To evaluate the effect of indocyanine green (ICG) diluted with glucose 5% on the human retina in an experimental setting in postmortem eyes and during surgery for macular hole formation...
  96. ncbi Prognostic significance of delayed structural recovery after macular hole surgery
    Ulrik C Christensen
    Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark
    Ophthalmology 116:2430-6. 2009
    ..To assess the prognostic significance for visual function of persistent subfoveal fluid and persistent photoreceptor layer discontinuity in eyes in which hole closure had been obtained 3 months after macular hole surgery...
  97. ncbi Spontaneous closure of traumatic macular hole
    Haruhiko Yamada
    Department of Ophthalmology, Kansai Medical University, Osaka, Japan
    Am J Ophthalmol 134:340-7. 2002
    ..To investigate the mechanism by which traumatic macular hole closes spontaneously...
  98. ncbi Retinal pigment epithelial tear following intravitreal pegaptanib sodium
    Mandeep Singh Dhalla
    Barnes Retina Institute, St Louis, Missouri, USA
    Am J Ophthalmol 141:752-4. 2006
    ..To report two cases of a retinal pigment epithelial tear after intravitreal injection of pegaptanib sodium. To our knowledge, this is the first report of this finding after intraocular antivascular endothelial growth factor therapy...
  99. ncbi Meta-analysis of chromovitrectomy with indocyanine green in macular hole surgery
    Eduardo B Rodrigues
    Department of Ophthalmology, Philipps University Marburg, Marburg, Germany
    Ophthalmologica 222:123-9. 2008
    ..To report a meta-analysis of the literature comparing internal limiting membrane (ILM) peeling with and without indocyanine green (ICG) staining in macular hole (MH) treatment...
  100. ncbi Ultrastructure of the membrana limitans interna after dye-assisted membrane peeling
    Tobias Brockmann
    Department of Ophthalmology, Electron Microscopy Center, University Hospital Jena, Jena, Germany
    Ophthalmologica 226:228-33. 2011
    ..A possible explanation might be seen in the known photosensitivity of ICG, which induces a stiffening and shrinkage of the ILM but also generates retinal toxic metabolites...
  101. ncbi Dissociated optic nerve fiber layer appearance after internal limiting membrane peeling for idiopathic macular hole
    Masahiro Miura
    Department of Ophthalmology, Tokyo Medical University, Kasumigaura Hospital, 3 20 1 Chuo, Ami, Inashiki, Ibaraki 300 0395, Japan
    Retina 23:561-3. 2003

Research Grants6

  1. New Tool to Study Neurochemical Modulation of Feeding
    SCOTT SHIPPY; Fiscal Year: 2005
    ..The unique capabilities of low-flow push-pull perfusion complement other sampling methodologies and are widely applicable to in vivo sampling studies. ..
  2. In Vivo Sampling to Study the Neurobiology of Gluacoma
    SCOTT SHIPPY; Fiscal Year: 2005
    ..Further, the ability to characterize chemical composition at the retina demonstrated in this study may be applicable to innovative studies of other diseases of the retina. ..
  3. Control of Eye Melanoma Metastasis
    Hans Grossniklaus; Fiscal Year: 2003
    ..Both the IFN and angiostatin will prevent the progression of micrometastases into metastases by anti-angiogenesis. Angiostatin will prevent metastases by an anti-melanoma invasion effect. ..
  4. SUBMACULAR SURGERY TRIALS PATHOLOGY CENTER
    Hans Grossniklaus; Fiscal Year: 2003
    ..Additionally, eyes obtained post-mortem from patients enrolled in the SST will be studied for pathologic correlation with clinical findings and outcomes. ..
  5. Eye Disease in Cuban-American and Puerto Rican Adults
    Ingrid Scott; Fiscal Year: 2003
    ..g. NEI-VFQ 25) and eye service use. Subjects who refuse will be questioned as to reason(s) for refusal. ..
  6. Control of Eye Melanoma Metastsis
    Hans E Grossniklaus; Fiscal Year: 2010
    ..The third aim determines the mechanism of combined angiostatin/IFN control of the micrometastases using methods in the first two aims. ..