epiretinal membrane

Summary

Summary: A membrane on the vitreal surface of the retina resulting from the proliferation of one or more of three retinal elements: (1) fibrous astrocytes; (2) fibrocytes; and (3) retinal pigment epithelial cells. Localized epiretinal membranes may occur at the posterior pole of the eye without clinical signs or may cause marked loss of vision as a result of covering, distorting, or detaching the fovea centralis. Epiretinal membranes may cause vascular leakage and secondary retinal edema. In younger individuals some membranes appear to be developmental in origin and occur in otherwise normal eyes. The majority occur in association with retinal holes, ocular concussions, retinal inflammation, or after ocular surgery. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p291)

Top Publications

  1. ncbi 25-gauge, sutureless vitrectomy and standard 20-gauge pars plana vitrectomy in idiopathic epiretinal membrane surgery: a comparative pilot study
    Stanislao Rizzo
    Santa Chiara Hospital, Eye Surgery Clinic, Via Roma 67, 56100, Pisa, Italy
    Graefes Arch Clin Exp Ophthalmol 244:472-9. 2006
  2. ncbi Clinical evaluation of the use of indocyanine green for peeling the internal limiting membrane in macular hole surgery
    Aude Husson-Danan
    Centre Hospitalier National d Ophtalmologie des Quinze Vingts, 28 rue de Charenton, 75012 Paris, France
    Graefes Arch Clin Exp Ophthalmol 244:291-7. 2006
  3. doi Circulating bone-marrow-derived endothelial precursor cells contribute to neovascularization in diabetic epiretinal membranes
    Ahmed M Abu El-Asrar
    Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Acta Ophthalmol 89:222-8. 2011
  4. doi High-resolution imaging of the photoreceptor layer in epiretinal membrane using adaptive optics scanning laser ophthalmoscopy
    Sotaro Ooto
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Ophthalmology 118:873-81. 2011
  5. doi Effect of Robo1 on retinal pigment epithelial cells and experimental proliferative vitreoretinopathy
    Lvzhen Huang
    Department of Ophthalmology, Peking University People s Hospital, Beijing, China
    Invest Ophthalmol Vis Sci 51:3193-204. 2010
  6. ncbi Comparison of visual function after epiretinal membrane removal by 20-gauge and 25-gauge vitrectomy
    Kazuaki Kadonosono
    Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan
    Am J Ophthalmol 142:513-5. 2006
  7. doi Correlation of visual recovery with presence of photoreceptor inner/outer segment junction in optical coherence images after epiretinal membrane surgery
    Y Mitamura
    Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba, Japan
    Br J Ophthalmol 93:171-5. 2009
  8. doi Expression of cyclo-oxygenase-2 and downstream enzymes in diabetic fibrovascular epiretinal membranes
    A M Abu El-Asrar
    Department of Ophthalmology, King Abdulaziz University Hospital, Old Airport Road, Riyadh, Saudi Arabia
    Br J Ophthalmol 92:1534-9. 2008
  9. doi Vital staining with indocyanine green: a review of the clinical and experimental studies relating to safety
    D Stanescu-Segall
    Department of Ophthalmology, King s College Hospital, London, UK
    Eye (Lond) 23:504-18. 2009
  10. doi Three-dimensional evaluation of vitreomacular traction and epiretinal membrane using spectral-domain optical coherence tomography
    Hideki Koizumi
    Vitreous Retina Macula Consultants of New York, Manhattan Eye, Ear, and Throat Hospital, New York, New York 10022, USA
    Am J Ophthalmol 145:509-517. 2008

Research Grants

Detail Information

Publications237 found, 100 shown here

  1. ncbi 25-gauge, sutureless vitrectomy and standard 20-gauge pars plana vitrectomy in idiopathic epiretinal membrane surgery: a comparative pilot study
    Stanislao Rizzo
    Santa Chiara Hospital, Eye Surgery Clinic, Via Roma 67, 56100, Pisa, Italy
    Graefes Arch Clin Exp Ophthalmol 244:472-9. 2006
    ..The aim of the study was to evaluate the safety and functional outcome of a small incision, sutureless vitrectomy in the treatment of idiopathic epiretinal membranes (ERM) compared with a standard 20-gauge vitrectomy system...
  2. ncbi Clinical evaluation of the use of indocyanine green for peeling the internal limiting membrane in macular hole surgery
    Aude Husson-Danan
    Centre Hospitalier National d Ophtalmologie des Quinze Vingts, 28 rue de Charenton, 75012 Paris, France
    Graefes Arch Clin Exp Ophthalmol 244:291-7. 2006
    ..To evaluate the role of indocyanine green (infracyanine) in macular hole surgery...
  3. doi Circulating bone-marrow-derived endothelial precursor cells contribute to neovascularization in diabetic epiretinal membranes
    Ahmed M Abu El-Asrar
    Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Acta Ophthalmol 89:222-8. 2011
    ..We investigated the presence of bone-marrow-derived endothelial precursor cells and the expression of the chemotactic pathway SDF-1 ⁄CXCL12)CXCR4 in PDR epiretinal membranes...
  4. doi High-resolution imaging of the photoreceptor layer in epiretinal membrane using adaptive optics scanning laser ophthalmoscopy
    Sotaro Ooto
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Ophthalmology 118:873-81. 2011
    To compare, in eyes with an idiopathic epiretinal membrane (ERM), photoreceptor cell structural abnormalities identified on high-resolution images obtained by adaptive optics scanning laser ophthalmoscopy (AO-SLO) with the severity of ..
  5. doi Effect of Robo1 on retinal pigment epithelial cells and experimental proliferative vitreoretinopathy
    Lvzhen Huang
    Department of Ophthalmology, Peking University People s Hospital, Beijing, China
    Invest Ophthalmol Vis Sci 51:3193-204. 2010
    ..This study was conducted to determine whether Robo1 is expressed in the retina of patients with proliferative retinal disease and whether it has a pathobiological role in the disease...
  6. ncbi Comparison of visual function after epiretinal membrane removal by 20-gauge and 25-gauge vitrectomy
    Kazuaki Kadonosono
    Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan
    Am J Ophthalmol 142:513-5. 2006
    ..To compare the efficacy and safety of 25-gauge vitrectomy with 20-gauge vitrectomy for macular pucker...
  7. doi Correlation of visual recovery with presence of photoreceptor inner/outer segment junction in optical coherence images after epiretinal membrane surgery
    Y Mitamura
    Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba, Japan
    Br J Ophthalmol 93:171-5. 2009
    To investigate the relationship between the presence of the photoreceptor inner and outer segment (IS/OS) junction and visual acuity after epiretinal membrane (ERM) surgery.
  8. doi Expression of cyclo-oxygenase-2 and downstream enzymes in diabetic fibrovascular epiretinal membranes
    A M Abu El-Asrar
    Department of Ophthalmology, King Abdulaziz University Hospital, Old Airport Road, Riyadh, Saudi Arabia
    Br J Ophthalmol 92:1534-9. 2008
    ....
  9. doi Vital staining with indocyanine green: a review of the clinical and experimental studies relating to safety
    D Stanescu-Segall
    Department of Ophthalmology, King s College Hospital, London, UK
    Eye (Lond) 23:504-18. 2009
    ..Although the use of ICG continues, on the balance of evidence, this review suggests that it is has the potential to produce subtle visual damage...
  10. doi Three-dimensional evaluation of vitreomacular traction and epiretinal membrane using spectral-domain optical coherence tomography
    Hideki Koizumi
    Vitreous Retina Macula Consultants of New York, Manhattan Eye, Ear, and Throat Hospital, New York, New York 10022, USA
    Am J Ophthalmol 145:509-517. 2008
    To delineate the 3-dimensional (3-D) relationship in vitreomacular traction (VMT) and idiopathic epiretinal membrane (ERM).
  11. ncbi Brilliant blue G selectively stains the internal limiting membrane/brilliant blue G-assisted membrane peeling
    Hiroshi Enaida
    Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Retina 26:631-6. 2006
    To report the use of the dye brilliant blue G (BBG) for staining of the internal limiting membrane (ILM) during macular hole (MH) and epiretinal membrane (ERM) surgery.
  12. ncbi Upregulation of RAGE and its ligands in proliferative retinal disease
    Sophia I Pachydaki
    Department of Ophthalmology, College of Physician and Surgeons, Columbia University, New York, NY 10032, USA
    Exp Eye Res 82:807-15. 2006
    ..These findings suggest a role for the proinflammatory RAGE axis in the pathogenesis of proliferative retinal diseases...
  13. doi Associations between macular findings by optical coherence tomography and visual outcomes after epiretinal membrane removal
    Min Hee Suh
    Department of Ophthalmology, Seoul National University College of Medicine, Korea
    Am J Ophthalmol 147:473-480.e3. 2009
    To identify characteristics measured by optical coherence tomography (OCT) that are correlated with visual outcome after epiretinal membrane (ERM) removal by pars plana vitrectomy (PPV).
  14. pmc Expression of hypoxia-inducible factor-1alpha and the protein products of its target genes in diabetic fibrovascular epiretinal membranes
    Ahmed M Abu El-Asrar
    Department of Ophthalmology, King Abdulaziz University Hospital, Airport Road, PO Box 245, Riyadh 11411, Saudi Arabia
    Br J Ophthalmol 91:822-6. 2007
    ....
  15. doi Incidence and characteristics of macular pucker formation after primary retinal detachment repair by pars plana vitrectomy alone
    Reshma C Katira
    Retina Group of Washington, Chevy Chase, Maryland, USA
    Retina 28:744-8. 2008
    ..To evaluate postoperative macular pucker formation in patients who underwent pars plana vitrectomy (PPV) for repair of primary rhegmatogenous retinal detachment (RD)...
  16. pmc Perifoveal vitreous detachment and its macular complications
    Mark W Johnson
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA
    Trans Am Ophthalmol Soc 103:537-67. 2005
    ..To evaluate the vitreoretinal relationship in eyes with idiopathic macular disorders putatively caused by vitreomacular traction associated with early stages of age-related posterior vitreous detachment (PVD)...
  17. doi [Preoperative assessment of topographic features in macular pucker using high-definition optical coherence tomography]
    L O Hattenbach
    Augenklinik, Klinikum Ludwigshafen
    Klin Monbl Augenheilkd 226:649-53. 2009
    ..In the current study, we sought to investigate whether the surgical removal of macular pucker can be facilitated by the preoperative assessment of topographic features using high-definition optical coherence tomography (HD-OCT)...
  18. doi Anatomic and functional outcome after 23-gauge vitrectomy, peeling, and intravitreal triamcinolone for idiopathic macular epiretinal membrane
    Lazaros Konstantinidis
    Hopital Ophtalmique Jules Gonin, University of Lausanne, Lausanne, Switzerland
    Retina 29:1119-27. 2009
    ....
  19. ncbi Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery
    Homayoun Tabandeh
    Department of Ophthalmology, University of Florida, Gainesville, Florida, USA
    Retina 24:714-20. 2004
    ..To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes...
  20. ncbi Retinal contraction and metamorphopsia scores in eyes with idiopathic epiretinal membrane
    Eiko Arimura
    Department of Ophthalmology, Kinki University School of Medicine, Osaka, Japan
    Invest Ophthalmol Vis Sci 46:2961-6. 2005
    ..software, which was developed to quantify retinal contraction, the authors investigated the relationship between the degree of retinal contraction and the degree of metamorphopsia in eyes with idiopathic epiretinal membrane (ERM).
  21. doi Prevalence and associations of epiretinal membranes in an adult Japanese population: the Funagata study
    R Kawasaki
    Department of Ophthalmology and Visual Science, Yamagata University Faculty of Medicine, Yamagata, Japan
    Eye (Lond) 23:1045-51. 2009
    ..To determine the prevalence and risk factors of epiretinal membranes (ERM) in a Japanese population...
  22. ncbi Epiretinal membrane formation with internal limiting membrane wrinkling after Nd:YAG laser membranotomy in valsalva retinopathy
    Alvin K H Kwok
    Department of Ophthalmology, The Hong Kong Sanatorium and Hospital, Hong Kong, China
    Am J Ophthalmol 136:763-6. 2003
    To report the location of premacular hemorrhage in Valsalva retinopathy and epiretinal membrane formation with internal limiting membrane (ILM) wrinkling after neodymium;yttrium-aluminum-garnet (Nd:YAG) laser membranotomy.
  23. ncbi Dissociated optic nerve fiber layer appearance of the fundus after idiopathic epiretinal membrane removal
    R Tadayoni
    Department of Ophthalmology, , , Assistance Publique, , , 75010 Paris, France
    Ophthalmology 108:2279-83. 2001
    PURPOSE: To report the appearance of the fundus, that is seen frequently after removal of an idiopathic epiretinal membrane and which we refer to as the dissociated optic nerve fiber layer appearance...
  24. ncbi Surgical management of epiretinal membrane in combined hamartomas of the retina and retinal pigment epithelium
    Xiao Zhang
    Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
    Retina 30:305-9. 2010
    ..The purpose of this study was to evaluate the surgical outcome of combined hamartomas of the retina and retinal pigment epithelium in five patients...
  25. doi Pathological changes in the vitreoretinal junction 1: epiretinal membrane formation
    D R J Snead
    Department of Pathology, University Hospital Coventry, Coventry, UK
    Eye (Lond) 22:1310-7. 2008
    b>Epiretinal membrane (ERM) formation is a common change resulting in disturbance of macular vision and predisposing to rhegmatogenous retinal detachment...
  26. ncbi Visual outcomes and complications of epiretinal membrane removal secondary to rhegmatogenous retinal detachment
    Matthew D Council
    Washington University School of Medicine, St Louis, Missouri, USA
    Ophthalmology 112:1218-21. 2005
    To examine visual outcomes after surgery for removal of epiretinal membrane after retinal detachment (RD) repair, and to identify possible complications.
  27. doi Inner segment/outer segment junction assessed by spectral-domain optical coherence tomography in patients with idiopathic epiretinal membrane
    Maiko Inoue
    Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan
    Am J Ophthalmol 150:834-9. 2010
    ..segment (IS/OS) junction before and after surgery by spectral-domain optical coherence tomography in patients undergoing idiopathic epiretinal membrane (ERM) surgery and to correlate these features with the functional outcomes.
  28. doi An in vivo evaluation of Brilliant Blue G in animals and humans
    M Remy
    Department of Ophthalmology, Ludwig Maximilians University, Mathildenstr 8, 80336 Munich, Germany
    Br J Ophthalmol 92:1142-7. 2008
    ..To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining properties in humans...
  29. pmc High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography
    Vivek J Srinivasan
    Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Ophthalmology 113:2054.e1-14. 2006
    ..To assess high-speed ultrahigh-resolution optical coherence tomography (OCT) image resolution, acquisition speed, image quality, and retinal coverage for the visualization of macular pathologies...
  30. doi Expression of advanced glycation end products and related molecules in diabetic fibrovascular epiretinal membranes
    Ahmed M Abu El-Asrar
    Department of Ophthalmology, King Saud University, Riyadh, Saudi Arabia
    Clin Experiment Ophthalmol 38:57-64; quiz 87. 2010
    ....
  31. ncbi Morphologically functional correlations of macular pathology connected with epiretinal membrane formation in spectral optical coherence tomography (SOCT)
    Janusz Michalewski
    The Jasne Blonia Eye Clinic, Lodz, Poland
    Graefes Arch Clin Exp Ophthalmol 245:1623-31. 2007
    ..In our study we use high-speed and high-resolution spectral OCT. Our goal was to present different forms of ERM and to analyze the influence of some morphological changes on visual acuity...
  32. doi Outcomes of idiopathic macular epiretinal membrane removal with and without internal limiting membrane peeling: a comparative study
    Ji Woong Lee
    Department of Ophthalmology, Pusan National University School of Medicine, Pusan, Korea
    Jpn J Ophthalmol 54:129-34. 2010
    To compare visual acuity and macular morphology after epiretinal membrane (ERM) removal with and without internal limiting membrane (ILM) peeling.
  33. pmc Intraoperative use of handheld spectral domain optical coherence tomography imaging in macular surgery
    Pouya N Dayani
    Department of Ophthalmology, Duke University Eye Center, Durham, NC 27710, USA
    Retina 29:1457-68. 2009
    ..To describe the intraoperative use of handheld spectral domain optical coherence tomography (SDOCT) imaging in macular surgery...
  34. doi Three-dimensional spectral-domain optical coherence tomography images of the retina in the presence of epiretinal membranes
    John E Legarreta
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 1638 NW 10th Avenue, Miami, FL 33136, USA
    Am J Ophthalmol 145:1023-1030. 2008
    ..To study the inner surface of the retina in the presence of epiretinal membranes (ERMs) using a prototype spectral-domain optical coherence tomography (SD-OCT) device...
  35. ncbi Functional outcome after trypan blue-assisted vitrectomy for macular pucker: a prospective, randomized, comparative trial
    Christos Haritoglou
    Department of Ophthalmology, Ludwig Maximilians University, Mathildenstrasse 8, 80336 Munich, Germany
    Am J Ophthalmol 138:1-5. 2004
    ..To evaluate functional outcome after the intraoperative application of 0.06% trypan blue during vitrectomy for macular pucker...
  36. doi Expression of myofibroblast activation molecules in proliferative vitreoretinopathy epiretinal membranes
    Ahmed M Abu El-Asrar
    Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Acta Ophthalmol 89:e115-21. 2011
    ..We investigated the expression of molecules involved in myofibroblast activation, migration and proliferation in PVR epiretinal membranes...
  37. doi Incidence of retinal detachment after small-incision, sutureless pars plana vitrectomy compared with conventional 20-gauge vitrectomy in macular hole and epiretinal membrane surgery
    Stanislao Rizzo
    Santa Chiara Hospital, Eye Surgery Clinic, Pisa, Italy
    Retina 30:1065-71. 2010
    ..retinal detachment (RD) after a small-incision, sutureless vitrectomy compared with conventional 20-gauge vitrectomy in macular hole and epiretinal membrane surgery and to investigate the clinical features and possible causative agents.
  38. doi Involvement of Müller glial cells in epiretinal membrane formation
    Andreas Bringmann
    Department of Ophthalmology, Faculty of Medicine, University of Leipzig, Eye Hospital, Leipzig, Germany
    Graefes Arch Clin Exp Ophthalmol 247:865-83. 2009
    ..regarding the role of Müller cells in periretinal membrane formation, especially in the early steps of epiretinal membrane formation, which involve an interaction of inflammatory and glial cells, and gives a survey of the factors ..
  39. ncbi Functional assessment of the possible toxicity of indocyanine green dye in macular hole surgery
    Mária Ferencz
    Department of Ophthalmology, Mária Street, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Am J Ophthalmol 142:765-70. 2006
    ..To evaluate the possible toxicity of indocyanine green (ICG) dye in macular hole surgery by comparing functional results after successful surgeries performed with and without staining...
  40. ncbi Prevalence and associations of epiretinal membranes in the visual impairment project
    Daniel J McCarty
    Marshfield Clinic Research Foundation, Marshfield, Wisconsin 54449, USA
    Am J Ophthalmol 140:288-94. 2005
    ..To determine the prevalence and factors associated with epiretinal membranes in a random sample of the population aged 40 years and older in Victoria, Australia...
  41. ncbi Incidence of endophthalmitis after 20- and 25-gauge vitrectomy
    Derek Y Kunimoto
    Retina Service, Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 114:2133-7. 2007
    ..To assess the incidence rate of endophthalmitis after 25-gauge pars plana vitrectomy and to compare it with the endophthalmitis rate after 20-gauge pars plana vitrectomy...
  42. doi Double staining with brilliant blue G and double peeling for epiretinal membranes
    Hiroyuki Shimada
    Department of Ophthalmology, School of Medicine, Nihon University, Surugadai, Kanda, Chiyodaku, Tokyo, Japan
    Ophthalmology 116:1370-6. 2009
    ..To compare methods of removing epiretinal membranes (ERM) and evaluate the usefulness of the double brilliant blue G (BBG) staining and double-peeling method...
  43. ncbi Outcome results in macular hole surgery: an evaluation of internal limiting membrane peeling with and without indocyanine green
    Tom G Sheidow
    Department of Ophthalmology, University of Western Ontario, London, Ontario, Canada
    Ophthalmology 110:1697-701. 2003
    ..To evaluate the anatomic closure rate and visual outcome in patients undergoing pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling with and without indocyanine green (ICG) enhancement...
  44. ncbi Optical coherence tomography of idiopathic macular epiretinal membranes before and after surgery
    P Massin
    Department of Ophthalmology, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Universite Paris 7, Paris, France
    Am J Ophthalmol 130:732-9. 2000
    To examine the preoperative and postoperative anatomical features of the macula using optical coherence tomography in patients who underwent surgery for epiretinal membrane and to correlate these features with functional results.
  45. doi Circulating fibrocytes contribute to the myofibroblast population in proliferative vitreoretinopathy epiretinal membranes
    A M Abu El-Asrar
    Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Br J Ophthalmol 92:699-704. 2008
    ..We investigated the presence of fibrocytes and the expression of their chemotactic pathways CCL21/CCR7 and CXCL12/CXCR4 in proliferative vitreoretinopathy (PVR) epiretinal membranes...
  46. ncbi A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery
    Gildo Y Fujii
    Microsurgery Advanced Design Laboratory, Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Ophthalmology 109:1807-12; discussion 1813. 2002
    ..To introduce and evaluate the infusion and aspiration rates and operative times of the 25-gauge transconjunctival sutureless vitrectomy system (TSV) DESIGN: In vitro experimental and comparative interventional study...
  47. ncbi Epiretinal membranes after extracapsular cataract surgery(1)
    C E Jahn
    Augenpraxisklinik, Kempten, Germany
    J Cataract Refract Surg 27:753-60. 2001
    ..To determine whether uneventful extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens (PC IOL) implantation induces epiretinal membranes (ERMs)...
  48. ncbi Pars Plana vitrectomy and epiretinal membrane peeling for vitreoretinal traction associated with combined hamartoma of the retina and retinal pigment epithelium (CHRRPE)
    L Konstantinidis
    Jules Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland
    Klin Monbl Augenheilkd 224:356-9. 2007
    ..appear slightly elevated and are characterised by varying amounts of pigmentation, vascular tortuosity, and epiretinal membrane formation that can be related to macular distortion...
  49. ncbi Intravitreous hepatocyte growth factor in patients with proliferative diabetic retinopathy: a case-control study
    Rafael Simo
    Diabetes Research Unit, Endocrinology Division, Hospital Univesitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
    Diabetes Res Clin Pract 71:36-44. 2006
    ..Our findings suggest that HGF is related to pathological conditions in which fibroproliferative processes or wound healing are involved rather than with angiogenesis itself...
  50. doi Correlation between thickening of the inner and outer retina and visual acuity in patients with epiretinal membrane
    Shigeta Arichika
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Shogoin, Sakyo ku, Kyoto, Japan
    Retina 30:503-8. 2010
    The purpose of this study was to examine the relationship between thickening of the inner and outer retinal layers and visual acuity in patients with idiopathic epiretinal membrane.
  51. ncbi Direct comparison of the migration of three cell types involved in epiretinal membrane formation
    Penny A Hogg
    St Paul s Unit of Ophthalmology, Department of Medicine, Royal Liverpool University Hospital, Liverpool, United Kingdom
    Invest Ophthalmol Vis Sci 43:2749-57. 2002
    ..pigment epithelial (RPE) cells, retinal glial (RG) cells, and fibroblasts (the cell types crucial in epiretinal membrane [ERM] formation) under identical microenvironmental conditions and thus to identify potential target areas ..
  52. doi Alphab-crystallin expression in epiretinal membrane of human proliferative diabetic retinopathy
    Zhenyu Dong
    Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan
    Retina 32:1190-6. 2012
    To examine the expression of alphaB-crystallin and its colocalization with vascular endothelial growth factor in the epiretinal membrane of human proliferative diabetic retinopathy.
  53. doi The long-term anatomical and visual effect of intravitreal triamcinolone injection during vitrectomy for the treatment of idiopathic macular epiretinal membrane
    Chi Chun Lai
    Department of Ophthalmology, Chang Gung Memorial Hospital, Linkuo Medical Center, Taoyuan, Taiwan
    Cutan Ocul Toxicol 30:292-7. 2011
    To compare the long-term anatomical and visual outcomes of patients with idiopathic epiretinal membrane (ERM) removed by vitrectomy and membrane peeling with or without the use of intravitreal injection of triamcinolone acetonide (IVTA).
  54. pmc Prevalence and risk factors for epiretinal membranes in a multi-ethnic United States population
    Ching Hui Ng
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Ophthalmology 118:694-9. 2011
    To describe the prevalence of and risk factors for epiretinal membrane (ERM) in a multi-ethnic population and to evaluate possible racial or ethnic differences.
  55. doi Intraoperative characteristics of the posterior vitreous cortex in patients with epiretinal membrane
    Toshifumi Yamashita
    Department of Ophthalmology, Kagoshima City Hospital, 20 17 Kajiya cho, Kagoshima 892 8580, Japan
    Graefes Arch Clin Exp Ophthalmol 246:333-7. 2008
    ..The aim of the study was to investigate the intraoperative characteristics of the posterior vitreous cortex in patients with epiretinal membranes...
  56. ncbi Surgical removal of idiopathic epiretinal membrane with or without the assistance of indocyanine green: a randomised controlled clinical trial
    Jost Hillenkamp
    Department of Ophthalmology, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Graefes Arch Clin Exp Ophthalmol 245:973-9. 2007
    To carry out a prospective investigation of the functional and morphological outcome of idiopathic epiretinal membrane (IEM) surgery with or without the assistance of indocyanine green (ICG) in a randomised controlled clinical trial.
  57. pmc Visual function and quality of life following vitrectomy and epiretinal membrane peel surgery
    S M S Ghazi-Nouri
    Moorfields Eye Hospital, London, UK
    Br J Ophthalmol 90:559-62. 2006
    To investigate the effect of epiretinal membrane (ERM) peel on patients' health related quality of life (HR-QOL) and to explore the association between self reported HR-QOL and conventional measures of visual function.
  58. ncbi Epiretinal membrane surgery with or without internal limiting membrane peeling
    Alvin Kh Kwok
    Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong
    Clin Experiment Ophthalmol 33:379-85. 2005
    The purpose of the present paper was to evaluate the visual outcome and recurrence rate of epiretinal membrane (ERM) formation following vitreoretinal surgery with and without internal limiting membrane (ILM) peel.
  59. ncbi Apoptosis and cell proliferation in proliferative retinal disorders: PCNA, Ki-67, caspase-3, and PARP expression
    Xinyuan Zhang
    Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Curr Eye Res 30:395-403. 2005
    ....
  60. doi Prevalence and associations of epiretinal membranes in a rural Chinese adult population: the Handan Eye Study
    Xin Rong Duan
    Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing, China
    Invest Ophthalmol Vis Sci 50:2018-23. 2009
    ..To determine the prevalence and association of epiretinal membranes (ERMs), as assessed by retinal photography and optical coherence tomography (OCT), in a Chinese population...
  61. pmc Lama1 mutations lead to vitreoretinal blood vessel formation, persistence of fetal vasculature, and epiretinal membrane formation in mice
    Malia M Edwards
    The Wilmer Eye Institute, Baltimore, MD 21287, USA
    BMC Dev Biol 11:60. 2011
    ..These mutants have a persistence of the fetal vasculature of vitreous (FVV) but lack a primary retinal vascular plexus. The present study provides a detailed analysis of astrocyte and vascular development in these Lama1 mutants...
  62. pmc Incidence and clinical characteristics of epiretinal membranes in children
    Hena A Khaja
    Mayo Clinic College of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Arch Ophthalmol 126:632-6. 2008
    ..To describe the incidence and clinical characteristics of epiretinal membranes (ERMs) in children...
  63. doi Racial difference in the prevalence of epiretinal membrane between Caucasians and Asians
    R Kawasaki
    Centre for Eye Research Australia, University of Melbourne, Australia
    Br J Ophthalmol 92:1320-4. 2008
    ..To describe the prevalence and risk factors of epiretinal membranes (ERM) in Asian Malays and to compare this with a white population...
  64. doi Idiopathic and secondary epiretinal membranes: do they differ in terms of morphology? An optical coherence tomography-based study
    Ahmet T Yazici
    Beyoglu Eye Training and Research Hospital, Istanbul, Turkey
    Retina 31:779-84. 2011
    ..The purpose of this study was to define the morphologic differences in idiopathic and secondary epiretinal membranes (ERMs) using a time domain optical coherence tomography...
  65. doi Role of the intravitreal growth factors in the pathogenesis of idiopathic epiretinal membrane
    Ludovico Iannetti
    Department of Ophthalmology, Sapienza University of Rome, Rome, Italy
    Invest Ophthalmol Vis Sci 52:5786-9. 2011
    The aim of the present study is to evaluate the roles of TGFs β1 and β2, glial cell line-derived neurotrophic factor (GDNF), and nerve growth factor (NGF) in the pathogenesis of idiopathic epiretinal membrane (ERM).
  66. doi Residual internal limiting membrane in epiretinal membrane surgery
    K Kifuku
    Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Br J Ophthalmol 93:1016-9. 2009
    To examine the degree of the residual internal limiting membrane (ILM) after epiretinal membrane (ERM) peeling.
  67. doi Gene expression profile of fibrovascular membranes from patients with proliferative diabetic retinopathy
    Shigeo Yoshida
    Department of Ophthalmology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Br J Ophthalmol 94:795-801. 2010
    ..The purpose of this study was to generate a profile of genes expressed in preretinal fibrovascular membranes (FVMs) from patients with proliferative diabetic retinopathy...
  68. ncbi Prevalence and risk factors for epiretinal membranes in a Japanese population: the Hisayama study
    Miho Miyazaki
    Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, 812 8582 Fukuoka, Japan
    Graefes Arch Clin Exp Ophthalmol 241:642-6. 2003
    ..To examine the prevalence and risk factors for epiretinal membranes (ERMs) in a sample Japanese population...
  69. doi Functional outcome of indocyanine green-assisted macular surgery: 7-year follow-up
    Burkhard von Jagow
    Department of Ophthalmology, Ludwig Maximilian University, Munich, Germany
    Retina 29:1249-56. 2009
    ..To evaluate the long-term functional results after surgery for macular pucker and macular holes with indocyanine green (ICG) staining of the internal limiting membrane...
  70. ncbi Negative indocyanine green staining of epiretinal membranes
    Robert E Foster
    Cincinnati Eye Institute, Ohio 45242, USA
    Retina 22:106-8. 2002
  71. doi Ability of new vital dyes to stain intraocular membranes and tissues in ocular surgery
    Eduardo B Rodrigues
    Vision Institute, Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
    Am J Ophthalmol 149:265-77. 2010
    To evaluate the ability of novel dyes to stain lens capsule (LC), internal limiting membrane (ILM), epiretinal membrane (ERM), and vitreous.
  72. doi Foveal structure and thickness of retinal layers long-term after surgical peeling of idiopathic epiretinal membrane
    Felix Treumer
    Department of Ophthalmology, University Medical Center Schleswig Holstein, Kiel, Germany
    Invest Ophthalmol Vis Sci 52:744-50. 2011
    To better understand the long-term effect of idiopathic epiretinal membrane peeling on retinal anatomy, the foveal structure and the thickness of individual retinal layers were analyzed with frequency-domain optical coherence tomography (..
  73. doi [High-resolution optical coherence tomography to evaluate vitreomacular traction before and after membrane peeling]
    M Georgopoulos
    Universitätsklinik für Augenheilkunde und Optometrie, Medizinische Universität Wien, Wahringer Gurtel 18 20, 1090, Wien, Osterreich
    Ophthalmologe 105:753-60. 2008
    ....
  74. ncbi Visual outcomes following vitrectomy and peeling of epiretinal membrane
    James G Wong
    Sydney Eye Hospital, Sydney, New South, Australia
    Clin Experiment Ophthalmol 33:373-8. 2005
    ....
  75. doi Trypan blue selective staining using whole blood for internal limiting membrane peeling during macular hole corrective surgery
    Chi Chun Lai
    Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Cutan Ocul Toxicol 28:114-8. 2009
    ..To prevent trypan blue (TB) retention and its potential toxicity by selectively staining the internal limiting membrane (ILM) with the aid of whole blood...
  76. doi Subfoveal pigment changes in patients with longstanding epiretinal membranes
    Nuno L Gomes
    Department of Ophthalmology, Columbia University, New York, New York, USA
    Am J Ophthalmol 147:865-8. 2009
    ..To characterize subfoveal changes in patients with longstanding epiretinal membranes (ERM)...
  77. ncbi Spectral domain high-definition optical coherence tomography in patients undergoing epiretinal membrane surgery
    Christiane I Falkner-Radler
    The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Lasersurgery, Department of Ophthalmology, Rudolf Foundation Clinic, Vienna, Austria
    Ophthalmic Surg Lasers Imaging 40:270-6. 2009
    ..To evaluate possible advantages of spectral domain optical coherence tomography (SD-OCT) in epiretinal membranes...
  78. ncbi Modified technique for safer indocyanine-green-assisted peeling of the internal limiting membrane during vitrectomy for macular hole repair
    Stanislao Rizzo
    Santa Chiara Hospital, Eye Surgery Clinic, Via Roma 67, 56100 Pisa, Italy
    Graefes Arch Clin Exp Ophthalmol 244:1615-9. 2006
    ..To reduce its toxicity and to avoid contact between ICG and the RPE, we have developed a modified technique by using autologous whole blood...
  79. ncbi Indocyanine green-assisted peeling of the epiretinal membrane in proliferative vitreoretinopathy
    Hidehisa Sakamoto
    Department of Ophthalmology, Beppu National Hospital, Japan
    Graefes Arch Clin Exp Ophthalmol 241:204-7. 2003
    ....
  80. ncbi Impact of optical coherence tomography on surgical decision making for epiretinal membranes and vitreomacular traction
    Diana V Do
    Retina Division, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Retina 27:552-6. 2007
    ....
  81. ncbi Advantages of using a ray-traced, three-dimensional rendering system for spectral domain Cirrus HD-OCT to visualize subtle structures of the vitreoretinal interface
    Carl Glittenberg
    Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery, Department of Ophthalmology, Rudolf Foundation Clinic, Vienna, Austria
    Ophthalmic Surg Lasers Imaging 40:127-34. 2009
    ..To create a ray-traced, three-dimensional display system for Cirrus high-definition optical coherence tomography (Carl Zeiss Meditec, Inc., Dublin, CA) that improves the visualization of subtle structures of the vitreoretinal interface...
  82. ncbi Clinical evaluation of the use of infracyanine green staining for internal limiting membrane peeling in epimacular membrane surgery
    A Feldman
    Service Universitaire d Ophtalmologie, Centre Hospitalier Intercommunal et Hopital Henri Mondor Assistance publique des hopitaux de Paris, Creteil France
    Eur J Ophthalmol 18:972-9. 2008
    To evaluate the use of infracyanine green (IFCG) staining in idiopathic epiretinal membrane (ERM) surgery.
  83. pmc Retreatment of full-thickness macular hole: predictive value of optical coherence tomography
    Jost Hillenkamp
    Department of Ophthalmology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
    Br J Ophthalmol 91:1445-9. 2007
    ....
  84. doi Vital dyes for macular surgery: a comparative electron microscopy study of the internal limiting membrane
    Ricarda G Schumann
    Department of Ophthalmology, Vitreoretinal and Pathology Unit, Ludwig Maximilians University, Munich, Germany
    Retina 29:669-76. 2009
    ..To analyze and compare the ultrastructure of the retinal cleavage plane of the internal limiting membrane (ILM) removed during dye-assisted macular surgery...
  85. ncbi What are vitreoretinal surgeons dyeing for?
    Anselm Kampik
    Retina 26:599-601. 2006
  86. ncbi Late reopening and spontaneous closure of previously repaired macular holes
    Jeffrey G Gross
    Carolina Retina Center, 7620 Trenholm Road Ext, Columbia, SC 29223, USA
    Am J Ophthalmol 140:556-8. 2005
    ..The features of late reopening with spontaneous closure in previously repaired macular holes are illustrated with optical coherence tomography (OCT)...
  87. doi The internal limiting membrane peeling with brilliant blue G staining for retinal detachment due to macular hole in high myopia
    Y Mochizuki
    Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, 812 8582, Japan
    Br J Ophthalmol 92:1009. 2008
  88. doi Twenty-three-gauge and 20-gauge vitrectomy in epiretinal membrane surgery
    Anton Haas
    Department of Ophthalmology, Medical University, Graz, Austria
    Retina 30:112-6. 2010
    ..The purpose of this study was to investigate the safety profile of the 23-gauge sutureless vitrectomy system in the treatment of epiretinal membranes compared with standard 20-gauge vitrectomy...
  89. doi Proliferative diabetic retinopathy with lymphocyte-rich epiretinal membrane associated with poor visual prognosis
    Satoru Kase
    Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Invest Ophthalmol Vis Sci 50:5909-12. 2009
    ..The aim of this study was to analyze lymphocyte infiltration using immunohistochemistry in proliferative diabetic retinopathy (PDR) membranes...
  90. ncbi Autologous platelets for macular hole surgery: the Sussex Eye Hospital experience
    Brendan J Vote
    Sussex Eye Hospital, Brighton, United Kingdom
    Clin Experiment Ophthalmol 32:472-7. 2004
    ..To evaluate the anatomical and visual outcomes of patients managed by macular hole surgery with adjunctive use of autologous platelets at Sussex Eye Hospital, UK...
  91. ncbi Surgical management of epiretinal membrane with indocyanine-green-assisted peeling
    Rolando Sorcinelli
    Department of Public Health, University of Cagliari, and Eye Clinic Maria Ausiliatrice, Cagliari, Italy
    Ophthalmologica 217:107-10. 2003
    To evaluate the surgical results of pars plana vitrectomy with peeling of the inner limiting membrane (ILM) in a preliminary series of 28 eyes with macular epiretinal membrane (ERM).
  92. pmc Epiretinal membrane removal in diabetic eyes: comparison of viscodissection with conventional methods of membrane peeling
    R A Grigorian
    The Institute of Ophthalmology and Visual Science, UMDNJ New Jersey Medical School, NJ, USA
    Br J Ophthalmol 87:737-41. 2003
    To compare conventional methods of epiretinal membrane peeling with viscodissection.
  93. ncbi [The surgical outcome of vitrectomy for idiopathic epiretinal membranes and foveal thickness before and after surgery]
    Masahiro Ishida
    Second Department of Ophthalmology, Toho University School of Medicine, 2 17 6 Ohashi, Meguro ku, Tokyo 153 8515, Japan
    Nihon Ganka Gakkai Zasshi 108:18-22. 2004
    ..To evaluate the surgical outcome of vitrectomy and foveal thickness before and after vitrectomy for idiopathic epiretinal membranes...
  94. ncbi Trypan blue- and indocyanine green-assisted epiretinal membrane surgery: clinical and histopathological studies
    A K H Kwok
    Department of Ophthalmology, Hong Kong Sanatorium and Hospital, Hong Kong, People s Republic of China
    Eye (Lond) 18:882-8. 2004
    To evaluate the clinical outcome and electron microscopic findings of trypan blue (Tb) and indocyanine green (ICG) assisted epiretinal membrane (ERM) surgery.
  95. ncbi Visual acuity after vitrectomy and epiretinal membrane peeling with or without premacular indocyanine green injection
    A Koestinger
    Unite Chirurgie Vitreo Retinienne, Hopital Ophtalmique Jules Gonin, Lausanne, Switzerland
    Eur J Ophthalmol 15:795-9. 2005
    To compare postoperative visual acuity of eyes operated for an epiretinal membrane (ERM), with or without intraoperative intraocular indocyanine green (ICG) injection.
  96. ncbi [OCT in epiretinal gliosis]
    A Hassenstein
    Augenklinik und Poliklinik, Universitatskrankenhaus Eppendorf, Hamburg
    Ophthalmologe 102:127-32. 2005
    ..In addition to biomicroscopy and fluorescein angiography, OCT images provide valuable information for a structural assessment of the macula, especially in evaluating the postoperative course of macular surgery...
  97. ncbi Immunohistochemical study of angiogenesis and proliferative activity in epiretinal membranes
    E Tsanou
    Department of Pathology Cytology, Medical School, University of Ioannina, Ioannina, Greece
    Int J Clin Pract 59:1157-61. 2005
    ..Our study confirms the presence of vascularisation in PDR membranes, as well as the presence of VEGF even in avascular PVR membranes, suggesting that immunoreactivity for VEGF may not be accompanied by angiogenesis...
  98. ncbi Assessment of macular function by multifocal electroretinography following epiretinal membrane surgery with indocyanine green-assisted internal limiting membrane peeling
    Timothy Y Y Lai
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, 147 K Argyle Street, Kowloon, Hong Kong, People s Republic of China
    Graefes Arch Clin Exp Ophthalmol 245:148-54. 2007
    To evaluate the changes in macular function and potential retinal toxicity in epiretinal membrane (ERM) surgery with indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling using multifocal electroretinography (mfERG).
  99. doi Spectral-domain optical coherence tomography for monitoring epiretinal membrane surgery
    Christiane I Falkner-Radler
    The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Lasersurgery, Department of Ophthalmology, Rudolf Foundation Clinic, Vienna, Austria
    Ophthalmology 117:798-805. 2010
    To assess prognostic factors in epiretinal membrane (ERM) surgery using spectral-domain (SD) optical coherence tomography (OCT).
  100. ncbi Expression of angiogenic and fibrogenic factors in proliferative vitreoretinal disorders
    Ahmed M Abu El-Asrar
    Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Int Ophthalmol 27:11-22. 2007
    ....
  101. ncbi Surgery for epimacular membrane: impact of retinal internal limiting membrane removal on functional outcome
    Etienne H Bovey
    Hopital Ophtalmique Jules Gonin, Lausanne, Switzerland
    Retina 24:728-35. 2004
    ..To examine eyes that underwent vitrectomy and peeling of epimacular membrane and to correlate the functional results with the presence or absence of an internal limiting membrane (ILM) in the histologic specimens...

Research Grants38

  1. QUALITY OF LIFE AND COST EFFECTIVENESS IN CMV RETINITIS
    John Kempen; Fiscal Year: 2002
    ..Subanalyses will assess what factors other than treatment strategy are associated with improved QOL and cost-effectiveness. ..
  2. Reading Center: Multicenter Uveitis Steroid Trial
    Michael Altaweel; Fiscal Year: 2007
    ..Photographs and angiograms will also be assessed for vascular nonperfusion, hemorrhage, retinal detachment, epiretinal membrane, glaucomatous disc changes, and nuclear and posterior subcapsular cataract...
  3. Genetic Regulation of Eye Development in Zebrafish
    Jeffrey Gross; Fiscal Year: 2009
    ..Syndrome (BCNS), a disorder that presents with ocular defects that include the formation of a glia-derived epiretinal membrane, retinal dysplasia and colobomas...
  4. Genetic Regulation of Eye Development in Zebrafish
    Jeffrey Gross; Fiscal Year: 2009
    ..Syndrome (BCNS), a disorder that presents with ocular defects that include the formation of a glia-derived epiretinal membrane, retinal dysplasia and colobomas...
  5. Genetic Regulation of Eye Development in Zebrafish
    Jeffrey M Gross; Fiscal Year: 2010
    ..Syndrome (BCNS), a disorder that presents with ocular defects that include the formation of a glia-derived epiretinal membrane, retinal dysplasia and colobomas...
  6. A GENE THERAPY-BASED APPROACH TO PREVENT PVR
    Andrius Kazlauskas; Fiscal Year: 2003
    ..Proliferative vitreoretinopathy (PVR) is a mutifactorial disease in which the growth and contraction of an epiretinal membrane (ERM) leads to retinal detachment...
  7. Eye Disease in Cuban-American and Puerto Rican Adults
    Ingrid Scott; Fiscal Year: 2003
    ..g. NEI-VFQ 25) and eye service use. Subjects who refuse will be questioned as to reason(s) for refusal. ..
  8. Visual outcomes & quality of life in CMV retinitis
    Jennifer Thorne; Fiscal Year: 2006
    ..abstract_text> ..
  9. Complications of Immunosupression for Eye Diseases
    John Kempen; Fiscal Year: 2007
    ..Analysis of the beneficial effects of immunosuppression, based on clinical information only, will be a secondary objective. ..
  10. The Insulin-Like Growth Factor System and Muller Cells
    Clyde Guidry; Fiscal Year: 2009
    ..Information gained from this study will improve our understanding of fibrocontractive retinal diseases and should represent a significant gain toward control of proliferative complications associated with diabetic retinopathy. ..
  11. Mechanistic-Based Non-Invasive Assessment of Retinal Damage in HAART Era
    Dirk Uwe G Bartsch; Fiscal Year: 2010
    ..Our team includes experts on retinal imaging, an expert in the study of HIV-related ocular complications, an expert in neurobehavioral research, and an expert on high-resolution optical coherence tomography. ..
  12. HIGH-RESOLUTION IMAGING OF OCULAR MELANOMA AND RETINA
    Dirk Uwe Bartsch; Fiscal Year: 2003
    ..Since we can measure and characterize these aberrations, we can develop digital inverse filter based on our experience in image reconstruction to correct the acquired images. ..
  13. Apoptosis in Retinal Detachments
    David Zacks; Fiscal Year: 2006
    ..This will allow us to develop and test new neuroprotective therapies for improving visual outcomes in retinal disease. ..
  14. Mechanistic-Based Non-Invasive Assessment of Retinal Damage in HAART Era
    Dirk Uwe Bartsch; Fiscal Year: 2006
    ..Our team includes experts on retinal imaging, an expert in the study of HIV-related ocular complications, an expert in neurobehavioral research, and an expert on high-resolution optical coherence tomography. ..
  15. Mechanistic-Based Non-Invasive Assessment of Retinal Damage in HAART Era
    Dirk Uwe Bartsch; Fiscal Year: 2007
    ..Our team includes experts on retinal imaging, an expert in the study of HIV-related ocular complications, an expert in neurobehavioral research, and an expert on high-resolution optical coherence tomography. ..
  16. The Insulin-Like Growth Factor System and Muller Cells
    Clyde Guidry; Fiscal Year: 2007
    ..Information gained from this study will improve our understanding of fibrocontractive retinal diseases and should represent a significant gain toward control of proliferative complications associated with diabetic retinopathy. ..
  17. The Insulin-Like Growth Factor System and Muller Cells
    Clyde Guidry; Fiscal Year: 2003
    ..The information gained from this study will not only improve our understanding of fibrocontractive processes, but should represent a significant gain toward control of this blinding complication of diabetic retinopathy. ..
  18. Autophagy and control of photoreceptor apoptosis
    David N Zacks; Fiscal Year: 2010
    ..In this project we will explore and define the manner in which autophagy regulates the activity of pro-death and pro-survival pathways within the photoreceptor of the detached retina. ..