ovarian hyperstimulation syndrome

Summary

Summary: A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.

Top Publications

  1. ncbi Flexible GnRH antagonist protocol versus GnRH agonist long protocol in patients with polycystic ovary syndrome treated for IVF: a prospective randomised controlled trial (RCT)
    Trifon G Lainas
    Eugonia Iatriki Erevna IVF Center, Athens, Greece
    Hum Reprod 25:683-9. 2010
  2. ncbi Severe early ovarian hyperstimulation syndrome following GnRH agonist trigger with the addition of 1500 IU hCG
    Ayse Seyhan
    Department of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada
    Hum Reprod 28:2522-8. 2013
  3. ncbi Review of clinical course and treatment of ovarian hyperstimulation syndrome (OHSS)
    Annick Delvigne
    IVF Centre, Department of Obstetrics Gynaecology, University Hospital St Pierre Free University of Brussels ULB, Brussels, Belgium
    Hum Reprod Update 9:77-96. 2003
  4. ncbi Preventing ovarian hyperstimulation syndrome: guidance for the clinician
    Peter Humaidan
    The Fertility Clinic, Skive Regional Hospital, Skive, Denmark
    Fertil Steril 94:389-400. 2010
  5. ncbi Serum anti-Müllerian hormone and estradiol levels as predictors of ovarian hyperstimulation syndrome in assisted reproduction technology cycles
    Tsung Hsien Lee
    Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
    Hum Reprod 23:160-7. 2008
  6. ncbi Ovarian hyperstimulation syndrome is correlated with a reduction of soluble VEGF receptor protein level and a higher amount of VEGF-A
    D Pietrowski
    Department of Obstetrics and Gynecology, Medical University Vienna, Vienna, Austria
    Hum Reprod 27:196-9. 2012
  7. ncbi The use of gonadotropin-releasing hormone (GnRH) agonist to induce oocyte maturation after cotreatment with GnRH antagonist in high-risk patients undergoing in vitro fertilization prevents the risk of ovarian hyperstimulation syndrome: a prospective rando
    Lawrence Engmann
    Center for Advanced Reproductive Services, Department of Obstetrics and Gynecology, Dowling South Building, University of Connecticut Health Center, Farmington, Connecticut 06030 6224, USA
    Fertil Steril 89:84-91. 2008
  8. ncbi Luteolysis induced by a gonadotropin-releasing hormone agonist is the key to prevention of ovarian hyperstimulation syndrome
    Shahar Kol
    Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel
    Fertil Steril 81:1-5. 2004
  9. ncbi Increased risk of ovarian hyperstimulation syndrome following controlled ovarian hyperstimulation in patients with vascular endothelial growth factor +405 cc genotype
    Hans Ivar Hanevik
    Fertilitetsklinikken Sør, Telemark Hospital, Porsgrunn, Norway
    Gynecol Endocrinol 28:845-9. 2012
  10. ncbi Ovarian stimulation by concomitant administration of cetrorelix acetate and HMG following Diane-35 pre-treatment for patients with polycystic ovary syndrome: a prospective randomized study
    Jiann Loung Hwang
    Department of Obstetrics and Gynecology, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
    Hum Reprod 19:1993-2000. 2004

Research Grants

Detail Information

Publications315 found, 100 shown here

  1. ncbi Flexible GnRH antagonist protocol versus GnRH agonist long protocol in patients with polycystic ovary syndrome treated for IVF: a prospective randomised controlled trial (RCT)
    Trifon G Lainas
    Eugonia Iatriki Erevna IVF Center, Athens, Greece
    Hum Reprod 25:683-9. 2010
    Women with polycystic ovary syndrome (PCOS) are at risk of developing ovarian hyperstimulation syndrome (OHSS) during ovarian stimulation...
  2. ncbi Severe early ovarian hyperstimulation syndrome following GnRH agonist trigger with the addition of 1500 IU hCG
    Ayse Seyhan
    Department of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada
    Hum Reprod 28:2522-8. 2013
    Is severe early ovarian hyperstimulation syndrome (OHSS) completely prevented with the GnRH agonist trigger and 1500 IU hCG luteal rescue protocol?
  3. ncbi Review of clinical course and treatment of ovarian hyperstimulation syndrome (OHSS)
    Annick Delvigne
    IVF Centre, Department of Obstetrics Gynaecology, University Hospital St Pierre Free University of Brussels ULB, Brussels, Belgium
    Hum Reprod Update 9:77-96. 2003
    The ovarian hyperstimulation syndrome (OHSS) is a rare iatrogenic complication of ovarian stimulation occurring during the luteal phase or during early pregnancy...
  4. ncbi Preventing ovarian hyperstimulation syndrome: guidance for the clinician
    Peter Humaidan
    The Fertility Clinic, Skive Regional Hospital, Skive, Denmark
    Fertil Steril 94:389-400. 2010
    To reevaluate ovarian hyperstimulation syndrome (OHSS) prevention techniques and provide a classification system for grading OHSS and evidence-based treatment strategies for preventing OHSS.
  5. ncbi Serum anti-Müllerian hormone and estradiol levels as predictors of ovarian hyperstimulation syndrome in assisted reproduction technology cycles
    Tsung Hsien Lee
    Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
    Hum Reprod 23:160-7. 2008
    ..The objective of this study is to determine whether the serum AMH level can predict ovarian hyperstimulation syndrome (OHSS) prior to selection of COS protocols.
  6. ncbi Ovarian hyperstimulation syndrome is correlated with a reduction of soluble VEGF receptor protein level and a higher amount of VEGF-A
    D Pietrowski
    Department of Obstetrics and Gynecology, Medical University Vienna, Vienna, Austria
    Hum Reprod 27:196-9. 2012
    b>Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening condition associated with increased vascular permeability...
  7. ncbi The use of gonadotropin-releasing hormone (GnRH) agonist to induce oocyte maturation after cotreatment with GnRH antagonist in high-risk patients undergoing in vitro fertilization prevents the risk of ovarian hyperstimulation syndrome: a prospective rando
    Lawrence Engmann
    Center for Advanced Reproductive Services, Department of Obstetrics and Gynecology, Dowling South Building, University of Connecticut Health Center, Farmington, Connecticut 06030 6224, USA
    Fertil Steril 89:84-91. 2008
    To determine whether there are any differences in the incidence of ovarian hyperstimulation syndrome (OHSS) and implantation rates in high-risk patients undergoing IVF using a protocol consisting of GnRH agonist trigger after cotreatment ..
  8. ncbi Luteolysis induced by a gonadotropin-releasing hormone agonist is the key to prevention of ovarian hyperstimulation syndrome
    Shahar Kol
    Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel
    Fertil Steril 81:1-5. 2004
    To review the available knowledge on the use of GnRH agonist for ovulation triggering as a means to prevent ovarian hyperstimulation syndrome (OHSS).
  9. ncbi Increased risk of ovarian hyperstimulation syndrome following controlled ovarian hyperstimulation in patients with vascular endothelial growth factor +405 cc genotype
    Hans Ivar Hanevik
    Fertilitetsklinikken Sør, Telemark Hospital, Porsgrunn, Norway
    Gynecol Endocrinol 28:845-9. 2012
    b>Ovarian hyperstimulation syndrome (OHSS) is a serious complication following controlled ovarian hyperstimulation (COH) for in vitro fertilization...
  10. ncbi Ovarian stimulation by concomitant administration of cetrorelix acetate and HMG following Diane-35 pre-treatment for patients with polycystic ovary syndrome: a prospective randomized study
    Jiann Loung Hwang
    Department of Obstetrics and Gynecology, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
    Hum Reprod 19:1993-2000. 2004
    ..We proposed a stimulation protocol incorporating Diane-35 and GnRH antagonist (Diane/cetrorelix protocol) and compared it with the GnRH agonist long protocol for PCOS patients...
  11. ncbi Evaluating the performance of serum antimullerian hormone concentration in predicting the live birth rate of controlled ovarian stimulation and intrauterine insemination
    Hang Wun Raymond Li
    Centre of Assisted Reproduction and Embryology, Department of Obstetrics and Gynaecology, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Fertil Steril 94:2177-81. 2010
    ..To evaluate the role of serum antimullerian hormone (AMH) concentration in predicting live birth outcome in controlled ovarian stimulation and intrauterine insemination (IUI)...
  12. ncbi Physiology and pathology of ovarian hyperstimulation syndrome
    Raul Gomez
    Instituto Universitario IVI, Universidad de Valencia, Valencia, Spain
    Semin Reprod Med 28:448-57. 2010
    b>Ovarian hyperstimulation syndrome (OHSS) occurs when ovaries primed with follicle-stimulating hormone/leuteinizing hormone (LH) are subsequently exposed to human chorionic gonadotropin (hCG)...
  13. ncbi Vascular endothelial growth factor receptor-2 activation induces vascular permeability in hyperstimulated rats, and this effect is prevented by receptor blockade
    Raul Gomez
    Fundación IVI para el Estudio de la Reproducción, Valencia, Spain
    Endocrinology 143:4339-48. 2002
    ..molecule released in response to hCG is believed to be the main feature in the development of ovarian hyperstimulation syndrome (OHSS) in women, and vascular endothelial growth factor (VEGF) is the main candidate as the human ..
  14. ncbi GnRH agonist for triggering of final oocyte maturation: time for a change of practice?
    P Humaidan
    The Fertility Clinic, Skive Regional Hospital, Resenvej 25, Skive, Denmark
    Hum Reprod Update 17:510-24. 2011
    GnRH agonist (GnRHa) triggering has been shown to significantly reduce the occurrence of ovarian hyperstimulation syndrome (OHSS) compared with hCG triggering; however, initially a poor reproductive outcome was reported after GnRHa ..
  15. ncbi 1,500 IU human chorionic gonadotropin administered at oocyte retrieval rescues the luteal phase when gonadotropin-releasing hormone agonist is used for ovulation induction: a prospective, randomized, controlled study
    Peter Humaidan
    The Fertility Clinic, Skive Regional Hospital, Resenvej 25, 7800 Skive, Denmark
    Fertil Steril 93:847-54. 2010
    ..To prospectively assess the reproductive outcome with a small bolus of hCG administered on the day of oocyte retrieval after ovulation induction with a GnRH agonist (GnRHa)...
  16. ncbi An OHSS-Free Clinic by segmentation of IVF treatment
    Paul Devroey
    Centre for Reproductive Medicine, UZ Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    Hum Reprod 26:2593-7. 2011
    Published data indicate a significant increase in ovarian hyperstimulation syndrome globally...
  17. ncbi Management of severe early ovarian hyperstimulation syndrome by re-initiation of GnRH antagonist
    T G Lainas
    Eugonia Iatriki Erevna IVF Unit, 7 Ventiri str, 11528, Athens, Greece
    Reprod Biomed Online 15:408-12. 2007
    ....
  18. ncbi Gonadotropin-releasing hormone agonist to induce final oocyte maturation prevents the development of ovarian hyperstimulation syndrome in high-risk patients and leads to improved clinical outcomes compared with coasting
    Andrea J DiLuigi
    The Center for Advanced Reproductive Services, Division of Reproductive Endocrinology and Infertility, University of Connecticut Health Center, Farmington, Connecticut 06030 6224, USA
    Fertil Steril 94:1111-4. 2010
    ..There were no cases of ovarian hyperstimulation syndrome in either group, and the LA trigger group had significantly more oocytes retrieved (26.9+/-9.5 vs...
  19. ncbi Agonist trigger: what is the best approach? Agonist trigger with aggressive luteal support
    Lawrence Engmann
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington, Connecticut 06030 6224, USA
    Fertil Steril 97:531-3. 2012
    Although gonadotropin-releasing hormone agonist (GnRHa) trigger is effective in the prevention of ovarian hyperstimulation syndrome, lower conception rates have been reported...
  20. ncbi Human chorionic gonadotropin-induced ovarian hyperstimulation syndrome is associated with up-regulation of vascular endothelial growth factor
    Tzu Hao Wang
    Department of Obstetrics and Gynecology, Chang Gung University Medical School, Chang Gung Memorial Hospital, Lin Kou Medical Center, 5 Fu Hsing Street, Tao Yuan 333, Taiwan
    J Clin Endocrinol Metab 87:3300-8. 2002
    b>Ovarian hyperstimulation syndrome (OHSS), a life-threatening complication occurring in stimulated ovarian cycles, arises from treatment with gonadotropin for induction of follicular maturation in infertile women...
  21. ncbi Incidence and prediction of ovarian hyperstimulation syndrome in women undergoing gonadotropin-releasing hormone antagonist in vitro fertilization cycles
    Evangelos G Papanikolaou
    Centre for Reproductive Medicine, University Hospital, Dutch Speaking Brussels Free University, Brussels, Belgium
    Fertil Steril 85:112-20. 2006
    To determine the incidence of ovarian hyperstimulation syndrome (OHSS) in a large series of GnRH antagonist-stimulated cycles and to assess the predictive value of E2 and the number of follicles on the day of hCG administration.
  22. ncbi Programming in vitro fertilization retrievals during working days after a gonadotropin-releasing hormone antagonist protocol with estrogen pretreatment: does the length of exposure to estradiol impact on controlled ovarian hyperstimulation outcomes?
    Anne Guivarc'h-Levêque
    Clinique Mutualiste La Sagesse, Rennes, France
    Fertil Steril 96:872-6. 2011
    ..To verify whether a variable number of days beyond the menses of estrogen (E) pretreatment may impact on controlled ovarian hyperstimulation (COH) outcomes and birth rate using a GnRH antagonist protocol...
  23. ncbi Treatment of ovarian hyperstimulation syndrome using a dopamine agonist and gonadotropin releasing hormone antagonist: a case series
    Nanette L Rollene
    Division of Reproductive Endocrinology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Fertil Steril 92:1169.e15-7. 2009
    To describe an outpatient treatment protocol for ovarian hyperstimulation syndrome (OHSS) that results in rapid normalization of symptoms with minimal side effects.
  24. ncbi GnRH antagonist in in vitro fertilization: where we are now
    D B Shapiro
    Reproductive Endocrinology Infertility, Reproductive Biology Associates, Atlanta, GA 30342, USA
    Minerva Ginecol 55:373-88. 2003
    ..As clinicians gain experience with these drugs, optimal treatment paradigms will likely emerge. This review will discuss current strategies and potential applications for the GnRH antagonists...
  25. ncbi GnRH agonist ovulation trigger and hCG-based, progesterone-free luteal support: a proof of concept study
    Shahar Kol
    Department of Obstetrics and Gynecology, IVF Unit, Rambam Health Care Campus, Haifa, Israel
    Hum Reprod 26:2874-7. 2011
    It is now well established that a GnRH agonist (GnRHa) ovulation trigger completely prevents ovarian hyperstimulation syndrome. However, early studies, using conventional luteal support, showed inferior clinical results following a GnRHa ..
  26. ncbi Update on ovarian hyperstimulation syndrome: Part 1--Incidence and pathogenesis
    Helge Binder
    Dept of Gynecology, Erlangen University Hospital, Erlangen, Germany
    Int J Fertil Womens Med 52:11-26. 2007
    b>Ovarian hyperstimulation syndrome (OHSS) is a rare and potentially life-threatening complication during controlled ovarian stimulation. It can be associated with severe morbidity and may even be fatal...
  27. ncbi Serum vascular endothelial growth factor concentrations in in vitro fertilization cycles predict the risk of ovarian hyperstimulation syndrome
    R Agrawal
    Department of Reproductive Endocrinology, University College London Medical School, The Middlesex Hospital and London Women s Clinic, United Kingdom
    Fertil Steril 71:287-93. 1999
    To explore the value of serum vascular endothelial growth factor (VEGF) concentrations during IVF cycles in predicting the risk of ovarian hyperstimulation syndrome (OHSS).
  28. ncbi Cabergoline as treatment of ovarian hyperstimulation syndrome: a review
    Theodoros Kalampokas
    Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
    Gynecol Endocrinol 29:98-100. 2013
    One of the most serious complications of assisted reproduction techniques is ovarian hyperstimulation syndrome (OHSS)...
  29. pmc Ovarian hyperstimulation syndrome caused by an FSH-secreting pituitary adenoma
    Odelia Cooper
    Cedars Sinai Medical Center, 8700 Beverly Boulevard, Room 2015, Los Angeles, CA 90048, USA
    Nat Clin Pract Endocrinol Metab 4:234-8. 2008
    ..A 40-year-old woman presented with galactorrhea and oligomenorrhea. She had a history of multiple ovarian cysts and pelvic pain...
  30. pmc Predicting and preventing ovarian hyperstimulation syndrome (OHSS): the need for individualized not standardized treatment
    Klaus Fiedler
    Kinderwunsch Centrum München, Fertility Center Munich, Lortzingstr 26, D 81241 Munich, Germany
    Reprod Biol Endocrinol 10:32. 2012
    b>Ovarian hyperstimulation syndrome (OHSS) is the most serious complication of controlled ovarian stimulation (COS) as part of assisted reproductive technologies (ART)...
  31. ncbi Ovarian hyperstimulation syndrome prevention strategies: in vitro maturation
    Jack Y J Huang
    The Ronald O Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, New York 10021, USA
    Semin Reprod Med 28:519-31. 2010
    The only reliable way to eliminate the risk of ovarian hyperstimulation syndrome (OHSS) is complete avoidance of gonadotropin ovarian stimulation...
  32. ncbi Obstetric outcome of women with in vitro fertilization pregnancies hospitalized for ovarian hyperstimulation syndrome: a case-control study
    Blandine Courbiere
    Department of Gynaecology and Obstetrics, Unit of Reproductive Medicine AP HM La Conception, Marseille, France
    Fertil Steril 95:1629-32. 2011
    To evaluate the obstetric outcome of women with IVF pregnancies hospitalized for ovarian hyperstimulation syndrome (OHSS).
  33. ncbi Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor
    Guillaume Smits
    Institut de Recherche Interdisciplinaire en Biologie Humaine et Moleculaire, Faculte de Medecine, Universite Libre de Bruxelles, Brussels, Belgium
    N Engl J Med 349:760-6. 2003
  34. ncbi Identification of the high-risk patient for ovarian hyperstimulation syndrome
    Evangelos G Papanikolaou
    Assisted Reproduction Unit, 1st OB GYN Department, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Semin Reprod Med 28:458-62. 2010
    b>Ovarian hyperstimulation syndrome (OHSS), an iatrogenic complication of ovarian stimulation for assisted reproduction, is a potentially life-threatening condition...
  35. ncbi Prevention of severe ovarian hyperstimulation syndrome in IVF with or without ICSI and embryo transfer: a modified 'coasting' strategy based on ultrasound for identification of high-risk patients
    T Al-Shawaf
    Fertility Centre, St Bartholomew s Hospital, West Smithfield, London, EC1A 7BE, UK
    Hum Reprod 16:24-30. 2001
    b>Ovarian hyperstimulation syndrome (OHSS) can be a severe and potentially life-threatening complication of ovarian stimulation for IVF...
  36. ncbi A comparative study on the outcomes of in vitro fertilization between women with polycystic ovary syndrome and those with sonographic polycystic ovary-only in GnRH antagonist cycles
    Yong Jin Kim
    Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, 28 Yonkeun Dong, Chongno Gu, Seoul 110 744, South Korea
    Arch Gynecol Obstet 282:199-205. 2010
    ..This study was performed to compare the outcomes of controlled ovarian stimulation (COH) and IVF between women with PCOS and those with sonographic PCO-only in GnRH antagonist cycles...
  37. ncbi Comparison of GnRH agonists and antagonists in assisted reproduction cycles of patients at high risk of ovarian hyperstimulation syndrome
    G Ragni
    Infertility Unit, Department of Obstetrics Gynaecology, University of Milan, Italy
    Hum Reprod 20:2421-5. 2005
    During IVF or ICSI cycles, ovarian hyperstimulation syndrome (OHSS) is a major problem...
  38. ncbi Management of severe OHSS using GnRH antagonist and blastocyst cryopreservation in PCOS patients treated with long protocol
    T G Lainas
    Eugonia Iatriki Erevna IVF Unit, Athens, Greece
    Reprod Biomed Online 18:15-20. 2009
    Despite the fact that many methods have been proposed for the management of severe ovarian hyperstimulation syndrome (OHSS), its prevention is mainly achieved by withholding human chorionic gonadotrophin (HCG) administration and cycle ..
  39. ncbi Coasting-what is the best formula?
    O Levinsohn-Tavor
    IVF and Infertility Unit, Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Hum Reprod 18:937-40. 2003
    Coasting is a method to decrease the incidence of ovarian hyperstimulation syndrome (OHSS), which involves withdrawing exogenous gonadotrophins until the serum estradiol (E(2)) level decreases...
  40. ncbi Symposium: Update on prediction and management of OHSS. A modern classification of OHSS
    Abraham Golan
    IVF Unit, Department of Obstetrics and Gynecology, Wolfson Medical Center, Holon 58100, Israel
    Reprod Biomed Online 19:28-32. 2009
    b>Ovarian hyperstimulation syndrome (OHSS) is a serious iatrogenic complication of ovarian stimulation using fertility medications...
  41. ncbi Targeting the vascular endothelial growth factor system to prevent ovarian hyperstimulation syndrome
    Sergio Reis Soares
    Instituto Valenciano de Infertilidad, IVI Lisboa Av Infante Dom Henrique, 333 H, 1800 282 Lisbon, Portugal
    Hum Reprod Update 14:321-33. 2008
    b>Ovarian hyperstimulation syndrome (OHSS) typically occurs when ovaries are primed with FSH/LH and subsequently exposed to hCG. The ultimate pathophysiological step underlying this clinical picture is increased vascular permeability (VP).
  42. ncbi Evidences for the existence of a low dopaminergic tone in polycystic ovarian syndrome: implications for OHSS development and treatment
    Raul Gomez
    Fundacion IVI, Institituto Universitario IVI Fundación Investigación Clinico de Valencia INCLIVA, 46015 Valencia, Spain
    J Clin Endocrinol Metab 96:2484-92. 2011
    ..Deregulation of the VEGF/VEGF receptor (VEGFR)-2 pathway leading to increased risk of ovarian hyperstimulation syndrome has been described in the ovary of patients suffering from polycystic ovarian syndrome (PCOS).
  43. ncbi Molecular mechanisms of ovarian hyperstimulation syndrome: paracrine reduction of endothelial claudin 5 by hCG in vitro is associated with increased endothelial permeability
    M Rodewald
    Department of Obstetrics and Gynecology, University of Ulm, Prittwitzstrasse 43, 89075 Ulm, Germany
    Hum Reprod 24:1191-9. 2009
    b>Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication of ovarian stimulation associated with severe vascular hyperpermeability...
  44. ncbi Signal mechanisms of vascular endothelial growth factor and interleukin-8 in ovarian hyperstimulation syndrome: dopamine targets their common pathways
    Shee Uan Chen
    Department of Obstetrics and Gynecology, National Taiwan University, No 7 Chung Shan South Road, Taipei, Taiwan
    Hum Reprod 25:757-67. 2010
    b>Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ovarian stimulation with massive ascites, pleural effusion and hemoconcentration...
  45. ncbi A qualitative systematic review of coasting, a procedure to avoid ovarian hyperstimulation syndrome in IVF patients
    Annick Delvigne
    IVF Centre, Department of Obstetrics Gynaecology, Free University of Brussels ULB, University Hospital St Pierre, Belgium
    Hum Reprod Update 8:291-6. 2002
    ..administration until the patient's serum estradiol (E2) level decreases, is often used to prevent ovarian hyperstimulation syndrome (OHSS)...
  46. ncbi Coasting acts through downregulation of VEGF gene expression and protein secretion
    J A Garcia-Velasco
    IVI Madrid, Rey Juan Carlos University, Spain
    Hum Reprod 19:1530-8. 2004
    This study was conducted to investigate the mechanisms by which coasting may be effective in decreasing the incidence of ovarian hyperstimulation syndrome (OHSS).
  47. pmc Ovarian hyperstimulation syndrome: pathophysiology and prevention
    Carolina O Nastri
    Departamento de Ginecologia e Obstetrícia da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo DGO HC FMRP USP, Avenida dos Bandeirantes 3900, 8 masculine Andar, Ribeirao Preto, Sao Paulo, Brazil, CEP 14049 900
    J Assist Reprod Genet 27:121-8. 2010
    To review and discuss the pathophysiology and prevention strategies for ovarian hyperstimulation syndrome (OHSS), which is a condition that may occur in up to 20% of the high risk women submitted to assisted reproductive technology cycles.
  48. pmc The non-ergot derived dopamine agonist quinagolide in prevention of early ovarian hyperstimulation syndrome in IVF patients: a randomized, double-blind, placebo-controlled trial
    Cristiano Busso
    IVI Valencia, Plaza de la Policia Local, 3, 46015 Valencia, Spain
    Hum Reprod 25:995-1004. 2010
    b>Ovarian hyperstimulation syndrome (OHSS) seems to be induced by the ovarian release of vascular endothelial growth factor (VEGF), which increases vascular permeability...
  49. ncbi Ovarian hyperstimulation syndrome: steps to maximize success and minimize effect for assisted reproductive outcome
    Puja S Gera
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Fertil Steril 94:173-8. 2010
    To investigate the strategies used to decrease the risk of ovarian hyperstimulation syndrome (OHSS) and their impact on pregnancy and live birth rates.
  50. pmc New insights into the pathophysiology of ovarian hyperstimulation syndrome. What makes the difference between spontaneous and iatrogenic syndrome?
    A Delbaere
    Clinique de Fertilité, Hopital Erasme, Brussels, Belgium
    Hum Reprod 19:486-9. 2004
    ..which display an increased sensitivity to hCG and are responsible for the development of spontaneous ovarian hyperstimulation syndrome (OHSS), provides for the first time the molecular basis for the physiopathology of spontaneous OHSS...
  51. ncbi Triggering with human chorionic gonadotropin or a gonadotropin-releasing hormone agonist in gonadotropin-releasing hormone antagonist-treated oocyte donor cycles: findings of a large retrospective cohort study
    Daniel Bodri
    Clinica Eugin, Barcelona, Spain
    Fertil Steril 91:365-71. 2009
    To compare pregnancy rates and the incidence of ovarian hyperstimulation syndrome (OHSS) in donor stimulation cycles where final maturation of oocytes was induced with recombinant hCG or GnRH agonist.
  52. ncbi Ovarian hyperstimulation syndrome and complications of ART
    Veerle Vloeberghs
    Leuven University Fertility Center, Department Obstetrics and Gynecology, UZ Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Best Pract Res Clin Obstet Gynaecol 23:691-709. 2009
    ..reproductive technology (ART) procedures (ovarian stimulation and oocyte aspiration), including ovarian hyperstimulation syndrome (OHSS), bleeding and infection...
  53. ncbi Serum vascular endothelial growth factor and Doppler blood flow velocities in in vitro fertilization: relevance to ovarian hyperstimulation syndrome and polycystic ovaries
    R Agrawal
    University College London Medical School, Department of Reproductive Endocrinology, The Middlesex Hospital, London Women s Clinic, United Kingdom
    Fertil Steril 70:651-8. 1998
    ..to Doppler blood flow velocities within ovarian and uterine blood vessels during IVF cycles and to assess their relation to ovarian hyperstimulation syndrome (OHSS) and polycystic ovaries (PCO)/polycystic ovary syndrome (PCOS).
  54. ncbi Inhibition of cyclooxygenase-2 (COX-2) by meloxicam decreases the incidence of ovarian hyperstimulation syndrome in a rat model
    Ramiro Quintana
    Instituto de Ginecología y fertilidad IFER, Buenos Aires, Argentina
    Fertil Steril 90:1511-6. 2008
    To investigate the effects of selective cyclooxygenase-2 (COX-2) inhibition on the ovarian hyperstimulation syndrome (OHSS) in an experimental model.
  55. ncbi New insights in mechanisms for development of ovarian hyperstimulation syndrome
    Miro Kasum
    Department of Obstetrics and Gynecology, School of Medicine, Zagreb University, Zagreb, Croatia
    Coll Antropol 34:1139-43. 2010
    The ovarian hyperstimulation syndrome (OHSS) is typically an iatrogenic complication of induction ovulation occurring during the luteal phase or early pregnancy...
  56. ncbi Can we eliminate severe ovarian hyperstimulation syndrome?
    Raoul Orvieto
    Department of Obstetrics and Gynecology, Rabin Medical Center, Petah Tiqva 49 100 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Hum Reprod 20:320-2. 2005
    ..between optimum ovarian stimulation and successful treatment outcome with minimal rate of severe ovarian hyperstimulation syndrome (OHSS) or multiple pregnancies...
  57. ncbi GnRH agonist for triggering final oocyte maturation in the GnRH antagonist ovarian hyperstimulation protocol: a systematic review and meta-analysis
    G Griesinger
    Department of Obstetrics and Gynecology, University Clinic of Schleswig Holstein, Campus Luebeck, Luebeck, Germany
    Hum Reprod Update 12:159-68. 2006
    ..of metaphase II oocytes; fertilization rate; embryo quality score; first trimester abortion rate; ovarian hyperstimulation syndrome (OHSS) incidence...
  58. ncbi Criteria of a successful coasting protocol for the prevention of severe ovarian hyperstimulation syndrome
    Ragaa Mansour
    The Egyptian IVF ET Center, 3, Road 161 Hadayek El Maadi, Cairo 11431, Egypt
    Hum Reprod 20:3167-72. 2005
    The aim of this study is to report a large series of patients (n = 1223) at risk of developing ovarian hyperstimulation syndrome (OHSS) who underwent coasting.
  59. ncbi Individualizing FSH dose for assisted reproduction using a novel algorithm: the CONSORT study
    F Olivennes
    Reprod Biomed Online 18:195-204. 2009
    ..GONAL-f) dose was assigned by the algorithm and was intended to be altered only for risk of ovarian hyperstimulation syndrome (OHSS). Primary end-point was number of oocytes retrieved...
  60. ncbi Can dopamine agonists reduce the incidence and severity of OHSS in IVF/ICSI treatment cycles? A systematic review and meta-analysis
    Mohamed A F M Youssef
    Department of Obstetrics and Gynaecology, Cairo University, Cairo, Egypt
    Hum Reprod Update 16:459-66. 2010
    Recently, dopamine agonists were proposed as a prophylactic treatment for ovarian hyperstimulation syndrome (OHSS) in women at high risk in IVF/ICSI treatment cycles.
  61. ncbi IVF outcome in women with PCOS, PCO and normal ovarian morphology
    Alexander Swanton
    Royal Berkshire Hospital, Reading, RG1 5AN, UK
    Eur J Obstet Gynecol Reprod Biol 149:68-71. 2010
    ..To examine the outcome of IVF in women who have normal ovaries, ovulatory PCO or PCOS...
  62. ncbi Prediction of ovarian hyperstimulation syndrome: why predict if we can prevent!
    Shahar Kol
    Hum Reprod 18:1557-8. 2003
  63. ncbi Association of FSH receptor and CYP19A1 gene variations with sterility and ovarian hyperstimulation syndrome
    Helge Binder
    Department of Obstetrics and Gynaecology, Erlangen University Hospital, Universitaetsstrasse 21 23, 91054 Erlangen, Germany
    Reproduction 135:107-16. 2008
    Severe ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication during assisted reproduction technology (ART). The aetiology of this condition is still not fully understood...
  64. ncbi Embryo freezing for preventing ovarian hyperstimulation syndrome: a Cochrane review
    A D'Angelo
    Department of Obstetrics and Gynaecology, University Hospital of Wales College of Medicine, Cardiff CF14 4XN, UK
    Hum Reprod 17:2787-94. 2002
    ..Cochrane reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and The Cochrane Library should be consulted for the most recent version of the review...
  65. ncbi The luteal phase after GnRH-agonist triggering of ovulation: present and future perspectives
    Peter Humaidan
    The Fertility Clinic, Odense University Hospital, Odense, Denmark
    Reprod Biomed Online 24:134-41. 2012
    ..of final oocyte maturation is the use of GnRH agonist (GnRHa) which reduces or even prevents ovarian hyperstimulation syndrome (OHSS)...
  66. ncbi Improving the patient's experience of IVF/ICSI: a proposal for an ovarian stimulation protocol with GnRH antagonist co-treatment
    Paul Devroey
    Center for Reproductive Medicine, Dutch Speaking Brussels Free University, Laarbeeklaan 101, Brussels 1090, Belgium
    Hum Reprod 24:764-74. 2009
    ..To facilitate the implementation of treatments that optimize the patient's experience, a simple GnRH antagonist protocol for use in predicted normal responders is proposed...
  67. ncbi Cabergoline: a safe, easy, cheap, and effective drug for prevention/treatment of ovarian hyperstimulation syndrome?
    M Manno
    Eur J Obstet Gynecol Reprod Biol 122:127-8. 2005
  68. ncbi Intravenous albumin for preventing severe ovarian hyperstimulation syndrome: a Cochrane review
    M Aboulghar
    The Egyptian IVF ET Center, Maadi, Cairo and Cairo University, Department of Obstetrics and Gynecology
    Hum Reprod 17:3027-32. 2002
    The effectiveness of human albumin administration in prevention of severe ovarian hyperstimulation syndrome (OHSS) was reviewed using the Cochrane Menstrual Disorders and Subfertility Group literature search strategy.
  69. ncbi Lysophosphatidic acid up-regulates expression of interleukin-8 and -6 in granulosa-lutein cells through its receptors and nuclear factor-kappaB dependent pathways: implications for angiogenesis of corpus luteum and ovarian hyperstimulation syndrome
    Shee Uan Chen
    Department of Obstetrics and Gynecology, National Taiwan University Hospital, No 7 Chung Shan South Road, Taipei, Taiwan
    J Clin Endocrinol Metab 93:935-43. 2008
    ..Angiogenic cytokines, including IL-6, IL-8, and vascular endothelial growth factor, increased in plasma and ascites of patients with ovarian hyperstimulation syndrome. The role of LPA in ovarian follicles is unclear.
  70. ncbi Symposium: Update on prediction and management of OHSS. Prevention of OHSS
    Mohamed Aboulghar
    Cairo University and the Egyptian IVF Center, Maadi, Cairo, Egypt
    Reprod Biomed Online 19:33-42. 2009
    b>Ovarian hyperstimulation syndrome (OHSS) is a major complication of ovulation induction. As the treatment of the syndrome is currently empirical, prevention is the most important aspect of its management...
  71. ncbi A chorionic gonadotropin-sensitive mutation in the follicle-stimulating hormone receptor as a cause of familial gestational spontaneous ovarian hyperstimulation syndrome
    Claudine Vasseur
    Service de Gynecologie Obstetrique, Centre Hospitalier Universitaire d Angers, Angers, France
    N Engl J Med 349:753-9. 2003
  72. ncbi The optimal length of 'coasting protocol' in women at risk of ovarian hyperstimulation syndrome undergoing in vitro fertilization
    Luciano G Nardo
    Department of Reproductive Medicine, Saint Mary s Hospital, Whitworth Park, Manchester, UK
    Hum Fertil (Camb) 9:175-80. 2006
    b>Ovarian hyperstimulation syndrome (OHSS) is a serious and potentially life-threatening complication following ovarian stimulation for in vitro fertilization (IVF)...
  73. ncbi Ovarian hyperstimulation syndrome caused by pituitary gonadotroph adenoma secreting follicle-stimulating hormone
    Mohammadreza Ghayuri
    Department of Obstetrics and Gynecology, MacDonald Women s Hospital, Case Western Reserve University, Cleveland, Ohio, USA
    Obstet Gynecol 109:547-9. 2007
    ..We report a highly exceptional case in which a gonadotroph adenoma was diagnosed in a patient with normal follicle-stimulating hormone (FSH) levels...
  74. ncbi Factors associated with ovarian hyperstimulation syndrome (OHSS) and its effect on assisted reproductive technology (ART) treatment and outcome
    Barbara Luke
    Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Fertil Steril 94:1399-404. 2010
    To evaluate factors associated with ovarian hyperstimulation syndrome (OHSS) and its effect on assisted reproductive technology (ART) treatment and outcome.
  75. ncbi Ovarian hyperstimulation syndrome prevention strategies: individualizing gonadotropin dose
    Francois Olivennes
    IVF center Eylau La Muette, Paris, France
    Semin Reprod Med 28:463-7. 2010
    The choice of the gonadotropin starting dose is an important parameter to prevent the onset of ovarian hyperstimulation syndrome (OHSS)...
  76. ncbi Effect of GnRH agonist and hCG treatment on VEGF, angiopoietin-2, and VE-cadherin: trying to explain the link to ovarian hyperstimulation syndrome
    Maria Cerrillo
    IVI Madrid, Rey Juan Carlos University, Madrid, Spain
    Fertil Steril 95:2517-9. 2011
    ..GnRHa triggering, trying to understand ovarian hyperstimulation syndrome pathophysiology...
  77. ncbi Treatment of ovarian hyperstimulation syndrome
    Mohamed Aboulghar
    Cairo University, Egypt
    Semin Reprod Med 28:532-9. 2010
    Mild forms of ovarian hyperstimulation syndrome (OHSS) do not require treatment. Moderate OHSS should be followed up on an outpatient basis with no specific treatment. Severe OHSS requires proper evaluation...
  78. ncbi Gonadotrophin-releasing hormone antagonists: will they replace the agonists?
    Ricardo E Felberbaum
    Department of Obstetrics and Gynaecology, Medical University of Lubeck, Ratzeburger Allee 160, 23 538 Lübeck, Germany
    Reprod Biomed Online 6:43-53. 2003
    ..Introducing flexible GnRH antagonist regimens should be the area of research in the near future...
  79. ncbi Safety and efficacy of a 3 mg dose of the GnRH antagonist cetrorelix in preventing premature LH surges: report of two large multicentre, multinational, phase IIIb clinical experiences
    F Olivennes
    Paris Sud University and Assisted Reproductive Technologies Unit, Hopital Cochin, Paris, France
    Reprod Biomed Online 6:432-8. 2003
    ..Pregnancy rates per embryo transfer were 27 and 28% respectively. Severe ovarian hyperstimulation syndrome (OHSS) occurred in <1% of cycles...
  80. ncbi Use of antagonists in ovarian stimulation protocols
    Luca Dal Prato
    Tecnobios Procreazione, Centre for Reproductive Health, Via Dante 15, I 40125 Bologna, Italy
    Reprod Biomed Online 10:330-8. 2005
    ..Pregnancy rate seems to be lower, but a decrease in the incidence of severe ovarian hyperstimulation syndrome (OHSS) is reported by several studies...
  81. ncbi A functioning FSH-secreting pituitary macroadenoma causing an ovarian hyperstimulation syndrome with multiple cysts resected and relapsed after leuprolide in a reproductive-aged woman
    Enrico Macchia
    Department of Endocrinology, University of Pisa, Pisa, Italy
    Gynecol Endocrinol 28:56-9. 2012
    Bioactive gonadotropin-secreting pituitary adenomas are very rare in fertile women and can cause an ovarian hyperstimulation syndrome (OHSS)...
  82. ncbi Spontaneous ovarian hyperstimulation syndrome and hyperreactio luteinalis are entities in continuum
    R Haimov-Kochman
    Department of Obstetrics and Gynecology, Hadassah Medical Center, Hebrew University, Mount Scopus, Jerusalem, Israel
    Ultrasound Obstet Gynecol 24:675-8. 2004
    Hyperreactio luteinalis (HL) and spontaneous ovarian hyperstimulation syndrome (OHSS) are both rare conditions during pregnancy...
  83. ncbi Outcome of pregnancies complicated by severe ovarian hyperstimulation syndrome (OHSS): a follow-up beyond the second trimester
    A Wiser
    IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer affiliated with Sackler Faculty of Medicine, Tel Aviv University, Israel
    Hum Reprod 20:910-4. 2005
    ..this study was to assess the obstetric complications for those pregnancies that are complicated by ovarian hyperstimulation syndrome (OHSS) and continue beyond the first trimester...
  84. ncbi Low-dose HCG may improve pregnancy rates and lower OHSS in antagonist cycles: a meta-analysis
    I P Kosmas
    Centre for Reproductive Medicine, Department of Obstetrics and Gynecology, Ioannina University School of Medicine, Ioannina, Greece
    Reprod Biomed Online 19:619-30. 2009
    ..This may be useful in the prevention of ovarian hyperstimulation syndrome. Relevant studies were identified on Medline...
  85. ncbi No room for cancellation, coasting, or ovarian hyperstimulation syndrome in oocyte donation cycles
    Eleuterio R Hernandez
    Clinica FivMadrid, Madrid, Spain
    Fertil Steril 91:1358-61. 2009
    ..2% developed symptoms of moderate (2.2%) or severe (1%) ovarian hyperstimulation syndrome, while none of the IVF donor cycles that were triggered with the GnRH agonist presented ovarian ..
  86. ncbi [The significance of the ovarian arteriolar vasodilatation in pathogenesis of the ovarian hyperstimulation syndrome]
    Mladenko Vasiljevic
    Srp Arh Celok Lek 134:344-7. 2006
    b>Ovarian hyperstimulation syndrome is a complication of the ovulation stimulation, most commonly by gonadotrophins. It frequently occurs in patients included in in vitro fertilization program...
  87. ncbi Comparisons of different dosages of gonadotropin-releasing hormone (GnRH) antagonist, short-acting form and single, half-dose, long-acting form of GnRH agonist during controlled ovarian hyperstimulation and in vitro fertilization
    Yao Yuan Hsieh
    Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan
    Taiwan J Obstet Gynecol 47:66-74. 2008
    ..We aimed to determine the minimum effective daily dose of GnRH antagonist in women undergoing COH. We also compared the efficiency of a GnRH antagonist and a GnRH agonist...
  88. ncbi Severe ovarian hyperstimulation syndrome after gonadotropin-releasing hormone (GnRH) agonist trigger and "freeze-all" approach in GnRH antagonist protocol
    Human Mousavi Fatemi
    Center for Reproductive Medicine, Dutch Speaking Free University Brussels, Brussels, Belgium Electronic address
    Fertil Steril 101:1008-11. 2014
    To report two cases with GnRH agonist triggering and a freeze-all approach in a GnRH antagonist protocol resulting in the development of severe ovarian hyperstimulation syndrome (OHSS), requiring hospitalization and peritoneal drainage.
  89. ncbi Plasma levels of free vascular endothelial growth factor(165) (VEGF(165)) are not elevated during gonadotropin stimulation in in vitro fertilization (IVF) patients developing ovarian hyperstimulation syndrome (OHSS): results of a prospective cohort study
    A Enskog
    Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Goteborg University, 413 45 Goteborg, Sweden
    Eur J Obstet Gynecol Reprod Biol 96:196-201. 2001
    ..VEGF(165)) concentrations exist during gonadotropin stimulation in IVF patients developing severe ovarian hyperstimulation syndrome (OHSS) compared to matched controls...
  90. ncbi Distinction between early and late ovarian hyperstimulation syndrome
    R S Mathur
    Bristol University Center for Reproductive Medicine, Bristol, UK
    Fertil Steril 73:901-7. 2000
    To compare patient and cycle characteristics among three study groups: early ovarian hyperstimulation syndrome (OHSS), late OHSS, and non-OHSS.
  91. ncbi Administration of intravenous albumin around the time of oocyte retrieval reduces pregnancy rate without preventing ovarian hyperstimulation syndrome: a systematic review and meta-analysis
    Byung Chul Jee
    Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Bundang Seongnam, Gyeonggi, Korea
    Gynecol Obstet Invest 70:47-54. 2010
    The aim of this meta-analysis was to evaluate whether IV albumin infusion around the time of oocyte retrieval prevents ovarian hyperstimulation syndrome (OHSS) and affects the pregnancy rate.
  92. pmc Are pregnancy rates compromised following embryo freezing to prevent OHSS?
    Gerard J Fitzmaurice
    Daisy Hill Hospital, 5 Hospital Road, Newry, BT35 8DR, N Ireland
    Ulster Med J 77:164-7. 2008
    To compare pregnancy rates with fresh and frozen embryo transfer in patients admitted to Royal Jubilee Maternity Service (RJMS), Belfast between January 1st 2004 and December 31st 2005 with ovarian hyperstimulation syndrome (OHSS).
  93. ncbi Treatment with gonadotropin-releasing hormone (GnRH) antagonists in women suppressed with GnRH agonist may avoid cycle cancellation in patients at risk for ovarian hyperstimulation syndrome
    Robert L Gustofson
    Walter Reed Army Medical Center, National Naval Medical Center, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Fertil Steril 85:251-4. 2006
    Forty-seven patients at high risk for ovarian hyperstimulation syndrome because of markedly elevated serum E2 levels on either long-luteal or microdose flare leuprolide acetate regimens were treated with ganirelix acetate...
  94. ncbi Metabolic characteristics of women who developed ovarian hyperstimulation syndrome
    Annick Delvigne
    Departments of Obstetrics and Gynaecology, IVF and Haematology, St Pierre University Hospital, Free University of Brussels, rue Haute, 322, 1000 Brussels, Belgium
    Hum Reprod 17:1994-6. 2002
    ..investigate whether a higher incidence of hyperinsulinism is found in women who have suffered from ovarian hyperstimulation syndrome (OHSS) as compared with other IVF patients...
  95. ncbi Intravenous albumin versus hydroxyethyl starch for the prevention of ovarian hyperstimulation in an in-vitro fertilization programme: a prospective randomized placebo controlled study
    O Gokmen
    Department of Assisted Reproduction, Zekai Tahir Burak Education and Research Hospital, Tunali Hilmi cad. 64/2, Kavaklidere, 06660 Ankara, Turkey
    Eur J Obstet Gynecol Reprod Biol 96:187-92. 2001
    ..Both HES and albumin significantly reduced the incidence of moderate, severe and overall incidence of OHSS. It is concluded that hydroxyethyl starch is a cheaper and safer alternative to Human Albumin in OHSS prevention...
  96. pmc Aggressive outpatient treatment of ovarian hyperstimulation syndrome with ascites using transvaginal culdocentesis and intravenous albumin minimizes hospitalization
    Stephen R Lincoln
    Genetics and IVF Institute, Fairfax, Virginia 22031, USA
    J Assist Reprod Genet 19:159-63. 2002
    To assess the effectiveness of outpatient treatment of Ovarian Hyperstimulation Syndrome associated with ascites.
  97. ncbi Withholding gonadotropins until human chorionic gonadotropin administration
    Rony Abdallah
    The Ronald O Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10021, USA
    Semin Reprod Med 28:486-92. 2010
    ..or suspending gonadotropin administration, can be an effective strategy for decreasing the risk of ovarian hyperstimulation syndrome (OHSS) while reducing cancelation rates...
  98. ncbi Vascular endothelial cadherin regulates vascular permeability: Implications for ovarian hyperstimulation syndrome
    A Villasante
    Instituto Valenciano de Infertilidad Madrid, C Santiago de Compostela, 88 bajo, 28035 Madrid, Spain
    J Clin Endocrinol Metab 92:314-21. 2007
    b>Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication of treatment with fertility drugs...
  99. ncbi Ovarian hyperstimulation syndrome: a potentially fatal complication of early pregnancy
    Justin J Madill
    Madigan Army Medical Center Emergency Department, Tacoma, Washington, USA
    J Emerg Med 35:283-6. 2008
    ..This presentation is typical of Ovarian Hyperstimulation Syndrome (OHSS), a diagnosis that may be unfamiliar to many Emergency Physicians...
  100. ncbi Does elective cryopreservation of all embryos from women at risk of ovarian hyperstimulation syndrome reduce the incidence of the condition?
    I Wada
    Bourn Hall Clinic, Bourn, Cambridge, UK
    Br J Obstet Gynaecol 100:265-9. 1993
    To analyse the incidence and factors associated with the ovarian hyperstimulation syndrome (OHS) in our IVF/GIFT programme before and after the introduction of a strategy to cryopreserve all embryos from women judged to be at risk.
  101. ncbi Use of intramuscular progesterone versus intravenous albumin for the prevention of ovarian hyperstimulation syndrome
    L Costabile
    Center for Reproductive Medicine and Infertility Therapy, Rome, Italy
    Gynecol Obstet Invest 50:182-5. 2000
    ..effectiveness of intramuscular progesterone with that of intravenous albumin in the prevention of ovarian hyperstimulation syndrome (OHSS)...

Research Grants19

  1. Role of mineralocorticoid receptor in primate ovarian function
    CHARLES CHAFFIN; Fiscal Year: 2009
    ..These include, for example, PCOS, ovarian cancer, and ovarian hyperstimulation syndrome (OHSS)...
  2. COOPERATIVE RESEARCH ON INFERTILITY IN PRIMATES
    Richard L Stouffer; Fiscal Year: 2010
    ..luteum, and whether alterations in Ang, EG-VEGF, as well as VEGF-A, cause ovarian disorders, such as ovarian hyperstimulation syndrome (OHSS)...
  3. Rosiglitazone and Clomiphene for Ovulation Induction
    Nicholas Cataldo; Fiscal Year: 2002
    ..FSH, but this is associated with a greater risk than clomiphene of both multiple gestation and ovarian hyperstimulation syndrome, which in its severe form can be life- threatening...
  4. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    PETER MCGOVERN; Fiscal Year: 2004
    ..Serious complications of these therapies include multiple pregnancy, ovarian hyperstimulation syndrome (OHSS), and premature delivery (even in singletons)...
  5. Granulosa Cell Function in Polycystic Ovary Syndrome
    R Chang; Fiscal Year: 2004
    ..has particular important clinical relevance as excessive granulosa cell stimulation may lead to ovarian hyperstimulation syndrome and potential serious life-threatening complications...
  6. Genes regulated by activin receptor II signaling in gonadotropes
    T Kumar; Fiscal Year: 2009
    ..These include ovarian hyperstimulation syndrome, amenorrhea and testicular defects.
  7. CELL SUBPOPULATIONS IN THE PRIMATE CORPUS LUTEUM
    Richard Stouffer; Fiscal Year: 2001
    ..Overall, the proposed research may have relevance to an understanding of certain ovarian disorders such as ovarian hyperstimulation syndrome and luteal phase defects where microvasculature growth may be disrupted.
  8. Cognitive dysfunction in neuropsychiatric-SLE
    Michael Lockshin; Fiscal Year: 2002
    ..Successful completion of this research will redefine the pathogenesis of cognitive dysfunction and suggest therapeutic targets for intervention...
  9. Fourteenth Ovarian Workshop
    John Davis; Fiscal Year: 2002
    ..New investigators will be invited to submit expanded abstracts that will be evaluated for scientific merit and competition for travel awards and the Cornelia P. Channing New Investigator Award. ..
  10. IGF-I SIGNALING IN GRANULOSA CELLS
    John Davis; Fiscal Year: 2004
    ..This new insight may uncover mechanistic defects that underlay disorders of folliculogenesis, premature ovarian failure and disorders such as polycystic ovarian syndrome. ..
  11. Wayne State University Clinical Translational Science
    Michael Diamond; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  12. Role of Egr-1 in Corpus Luteum Function
    John Davis; Fiscal Year: 2006
    ..abstract_text> ..
  13. Fifteenth Ovarian Workshop
    John Davis; Fiscal Year: 2004
    ..New investigators will be invited to submit expanded abstracts that will be evaluated for scientific merit and competition for travel awards and the Cornelia P. Channing New Investigator Award. ..
  14. Angiogenesis Induction by Vasculogenic Progenitor Cells
    Joseph Itskovitz Eldor; Fiscal Year: 2006
    ..We expect that this research will establish the foundation for an effective therapeutic modality using hES cells for some of the most leading causes of morbidity and mortality in the world. ..
  15. SEX HORMONES AND BODY FLUID REGULATION
    NINA STACHENFELD; Fiscal Year: 2003
    ....
  16. Short-term course in human embryonic stem cell culture techniques
    Joseph Itskovitz Eldor; Fiscal Year: 2008
    ..Thus, this guiding program will further encourage the distribution and research based on hESC. [unreadable] [unreadable] [unreadable]..
  17. BIOLOGICAL BASIS OF THE PERIMENOPAUSE
    DAVID SEIFER; Fiscal Year: 2002
    ....
  18. Estrogen & Progesterone Effects on Orthostatic Tolerance
    NINA STACHENFELD; Fiscal Year: 2010
    ..We also expect that the data in these studies will provide a basis to study the impact of sex hormones on diseases related to compromised peripheral circulation, such as hypertension, Raynaud's phenomenon and diabetes ..
  19. Infrastructure for Human Embryonic Stem Cells Productio*
    Joseph Itskovitz Eldor; Fiscal Year: 2007
    ..These improvements will constitute the ability to grow and propagate hESCs in large quantities in conditions that promote both research and clinical utilization of these cells. ..