rupture

Summary

Summary: Forcible or traumatic tear or break of an organ or other soft part of the body.

Top Publications

  1. ncbi Randomised controlled trials of immediate weight-bearing mobilisation for rupture of the tendo Achillis
    M L Costa
    School of Medicine, The University of East Anglia, Norwich NR4 7TJ, Norfolk, UK
    J Bone Joint Surg Br 88:69-77. 2006
  2. ncbi The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis
    L Stefan Lohmander
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Am J Sports Med 35:1756-69. 2007
  3. ncbi Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture
    Andrew C Newby
    Bristol Heart Institute, University of Bristol, United Kingdom
    Physiol Rev 85:1-31. 2005
  4. ncbi Preventing heart injury during negative pressure wound therapy in cardiac surgery: assessment using real-time magnetic resonance imaging
    Malin Malmsjo
    Department of Medicine, Lund University Hospital, Lund, Sweden
    J Thorac Cardiovasc Surg 138:712-7. 2009
  5. ncbi Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques
    Atilla Yilmaz
    Medical Clinic II, University of Erlangen Nuremberg, Ulmenweg 18, 91054 Erlangen, Germany
    Atherosclerosis 176:101-10. 2004
  6. ncbi Cumulative incidence of achilles tendon rupture and tendinopathy in male former elite athletes
    Urho M Kujala
    Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland
    Clin J Sport Med 15:133-5. 2005
  7. doi Single-row versus double-row arthroscopic rotator cuff repair: a prospective randomized clinical study
    Andrea Grasso
    Villa Valeria Clinic, Rome, Italy
    Arthroscopy 25:4-12. 2009
  8. ncbi Pulmonary artery rupture induced by a pulmonary artery catheter: a case report and review of the literature
    Alexandre R Abreu
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Miami School of Medicine, Miami, Florida, USA
    J Intensive Care Med 19:291-6. 2004
  9. ncbi The value of conservative treatment in ruptures of the anterior cruciate ligament (ACL)
    Alexander Strehl
    Department of Orthopaedic Surgery, University Hospital Inselspital, Bern, Switzerland
    J Trauma 62:1159-62. 2007
  10. pmc A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps
    Yuliya Vengrenyuk
    Department of Biomedical Engineering, City College of New York, Convent Avenue and 138th Street, New York, NY 10031, USA
    Proc Natl Acad Sci U S A 103:14678-83. 2006

Detail Information

Publications311 found, 100 shown here

  1. ncbi Randomised controlled trials of immediate weight-bearing mobilisation for rupture of the tendo Achillis
    M L Costa
    School of Medicine, The University of East Anglia, Norwich NR4 7TJ, Norfolk, UK
    J Bone Joint Surg Br 88:69-77. 2006
    ..controlled trials in order to assess the potential benefits of immediate weight-bearing mobilisation after rupture of the tendo Achillis...
  2. ncbi The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis
    L Stefan Lohmander
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Am J Sports Med 35:1756-69. 2007
    ....
  3. ncbi Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture
    Andrew C Newby
    Bristol Heart Institute, University of Bristol, United Kingdom
    Physiol Rev 85:1-31. 2005
    ..Plaque rupture represents a failure of intimal remodeling, where the fibrous cap overlying an atheromatous core of lipid ..
  4. ncbi Preventing heart injury during negative pressure wound therapy in cardiac surgery: assessment using real-time magnetic resonance imaging
    Malin Malmsjo
    Department of Medicine, Lund University Hospital, Lund, Sweden
    J Thorac Cardiovasc Surg 138:712-7. 2009
    Heart rupture is a devastating complication to negative pressure wound therapy in cardiac surgery. Also, reduced cardiac output during negative pressure wound therapy has been reported...
  5. ncbi Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques
    Atilla Yilmaz
    Medical Clinic II, University of Erlangen Nuremberg, Ulmenweg 18, 91054 Erlangen, Germany
    Atherosclerosis 176:101-10. 2004
    ..02). DC clusters with a strong HLA-DR expression and frequent DC-T cell contacts were located particularly in the rupture-prone plaque regions and at complications...
  6. ncbi Cumulative incidence of achilles tendon rupture and tendinopathy in male former elite athletes
    Urho M Kujala
    Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland
    Clin J Sport Med 15:133-5. 2005
    To study the cumulative incidence of Achilles tendon rupture and tendinopathy among former top-level athletes.
  7. doi Single-row versus double-row arthroscopic rotator cuff repair: a prospective randomized clinical study
    Andrea Grasso
    Villa Valeria Clinic, Rome, Italy
    Arthroscopy 25:4-12. 2009
    ..The purpose of this study was to compare the clinical outcome of arthroscopic rotator cuff repair with single-row and double-row techniques...
  8. ncbi Pulmonary artery rupture induced by a pulmonary artery catheter: a case report and review of the literature
    Alexandre R Abreu
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Miami School of Medicine, Miami, Florida, USA
    J Intensive Care Med 19:291-6. 2004
    ..The authors describe a case of a patient who developed massive hemoptysis after placement of a PAC that caused a rupture of the pulmonary artery with pseudoaneurysm formation...
  9. ncbi The value of conservative treatment in ruptures of the anterior cruciate ligament (ACL)
    Alexander Strehl
    Department of Orthopaedic Surgery, University Hospital Inselspital, Bern, Switzerland
    J Trauma 62:1159-62. 2007
    ..Patient selection was performed using a preoperative screening protocol based on the structural damage, clinical symptoms, compliance, sportive activity, and the consent of a well-informed patient...
  10. pmc A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps
    Yuliya Vengrenyuk
    Department of Biomedical Engineering, City College of New York, Convent Avenue and 138th Street, New York, NY 10031, USA
    Proc Natl Acad Sci U S A 103:14678-83. 2006
    In this article, we advance a hypothesis for the rupture of thin fibrous cap atheroma, namely that minute (10-mum-diameter) cellular-level microcalcifications in the cap, which heretofore have gone undetected because they lie below the ..
  11. ncbi A meta-analysis of the incidence of anterior cruciate ligament tears as a function of gender, sport, and a knee injury-reduction regimen
    Chadwick C Prodromos
    Illinois Sports Medicine and Orthopaedic Centers, Glenview, Illinois 60025, USA
    Arthroscopy 23:1320-1325.e6. 2007
    ..Our purpose was to apply meta-analysis to the entire applicable literature to generate accurate estimates of the true incidences of ACL tear as a function of gender, sport, and injury-reduction training...
  12. ncbi Incidence and risk factors for graft rupture and contralateral rupture after anterior cruciate ligament reconstruction
    Lucy Salmon
    Australian Institute of Musculoskeletal Research and The School of Physiotherapy, University of Sydney, Sydney, Australia
    Arthroscopy 21:948-57. 2005
    The aim of this study was to determine the rates of contralateral anterior cruciate ligament (ACL) rupture and of ACL graft rupture after ACL reconstruction using either patellar tendon or hamstring tendon autograft, and to identify any ..
  13. ncbi Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage
    Renu Virmani
    CVPath, International Registry of Pathology, Gaithersburg, MD 20878, USA
    Arterioscler Thromb Vasc Biol 25:2054-61. 2005
    ..This review discusses the potential role of intraplaque vasa vasorum in lesion instability as it relates to plaque rupture.
  14. ncbi Single-row versus double-row arthroscopic rotator cuff repair in small- to medium-sized tears
    Nuri Aydin
    Department of Orthopedics and Traumatology, Uskudar State Hospital, Istanbul, Turkey
    J Shoulder Elbow Surg 19:722-5. 2010
    ..Double-row rotator cuff repair leads to superior cuff integrity and clinical results compared with single-row repair...
  15. ncbi The COL5A1 gene is associated with increased risk of anterior cruciate ligament ruptures in female participants
    Michael Posthumus
    Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Am J Sports Med 37:2234-40. 2009
    ..The COL5A1 gene, which encodes for the alpha1 chain of type V collagen, has been shown to be associated with Achilles tendon injuries...
  16. ncbi CT cystography with multiplanar reformation for suspected bladder rupture: experience in 234 cases
    David P N Chan
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, Hong Kong
    AJR Am J Roentgenol 187:1296-302. 2006
    CT cystography has replaced conventional cystography in the evaluation of patients with suspected bladder rupture in most trauma centers...
  17. ncbi Strain energy density as a rupture criterion for the kidney: impact tests on porcine organs, finite element simulation, and a baseline comparison between human and porcine tissues
    J G Snedeker
    ETH and University Zurich, Zurich, Switzerland
    J Biomech 38:993-1001. 2005
    ..Impact energy was incrementally increased until visible rupture occurred...
  18. ncbi Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy
    A N Corps
    Rheumatology Research Unit, Department of Trauman and Orthopedics, Addenbrooke s Hospital, Cambridge, UK
    Rheumatology (Oxford) 45:291-4. 2006
    ..To determine the expression of mRNA encoding the proteoglycans aggrecan, versican, biglycan and decorin in mid-tendon samples of chronic painful Achilles tendinopathy and ruptured Achilles tendons, compared with normal tendons...
  19. doi Joint immobilization reduces the expression of sensory neuropeptide receptors and impairs healing after tendon rupture in a rat model
    Daniel K I Bring
    Section of Orthopaedics and Sports Medicine, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    J Orthop Res 27:274-80. 2009
    Healing after mobilization versus immobilization was assessed in a model of rat Achilles tendon rupture, by RT-PCR at 8 and 17 days and by histological analyses at 14 and 28 days postrupture...
  20. ncbi Long-term results after primary repair or non-surgical treatment of anterior cruciate ligament rupture: a randomized study with a 15-year follow-up
    A Meunier
    Division of Orthopaedics and Sports Medicine, Department of Neurosience and Locomotion, Faculty of Health Sciences, University of Linkoping, Linkoping, Sweden
    Scand J Med Sci Sports 17:230-7. 2007
    ..to primary repair (augmented or non-augmented) or non-surgical treatment of an anterior cruciate ligament (ACL) rupture. The subjective outcome was similar between the groups, with no difference regarding activity level and knee-..
  21. pmc Ipsilateral graft and contralateral ACL rupture at five years or more following ACL reconstruction: a systematic review
    Rick W Wright
    Department of Orthopaedics and Rehabilitation, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Bone Joint Surg Am 93:1159-65. 2011
    ..Little evidence exists regarding the intermediate to long-term risk of these events...
  22. doi Anterior cruciate ligament injury in elite football: a prospective three-cohort study
    Markus Waldén
    Department of Medical and Health Sciences, Linkoping University, Linkoping, Sweden
    Knee Surg Sports Traumatol Arthrosc 19:11-9. 2011
    ..These findings suggest that future preventive research primarily should address the young female football player...
  23. ncbi The role of shear stress in the generation of rupture-prone vulnerable plaques
    C J Slager
    Hemodynamics Laboratory, Department of Biomedical Engineering, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
    Nat Clin Pract Cardiovasc Med 2:401-7. 2005
    ..This change causes shear stress to increase, which as a new condition may transform the lesion into a rupture-prone vulnerable plaque...
  24. doi The role of pro-inflammatory and immunoregulatory cytokines in tendon healing and rupture: new insights
    G Schulze-Tanzil
    Department of Trauma and Reconstructive Surgery, Charite Universitatsmedizin, Campus Benjamin Franklin, Berlin, Germany
    Scand J Med Sci Sports 21:337-51. 2011
    ....
  25. doi Suture-button versus screw fixation in a syndesmosis rupture model: a biomechanical comparison
    Sandeep P Soin
    Baltimore, MD, USA
    Foot Ankle Int 30:346-52. 2009
    Flexible suture-button devices are used to stabilize the distal tibiofibular joint after syndesmotic rupture, but little is known about how they affect fibular motion during cyclic physiological loading...
  26. doi Management of chronic ruptures of the Achilles tendon
    Nicola Maffulli
    Department of Trauma and Orthopaedic Surgery, Keele University School of Medicine, Thornburrow Drive, Hartshill, Stoke on Trent ST4 7QB Staffs, England
    J Bone Joint Surg Am 90:1348-60. 2008
    ..5 cm. Compared with acute injuries, chronic injuries are associated with a higher rate of postoperative infection and more prolonged recovery...
  27. ncbi Flexor tendon injuries following locked volar plating of distal radius fractures
    Andrew W Cross
    Allegheny Hand Center, Allegheny General Hospital, Pittsburgh, PA 15212, USA
    J Hand Surg Am 33:164-7. 2008
    ..We suggest close follow-up of all fractures in which the distal end of the plate is anterior to the radial rim and removal of hardware if symptoms suggest tendon irritation...
  28. ncbi Globe rupture following penetrating keratoplasty: how often, why, and what can we do to prevent it?
    Mark J Elder
    Ophthalmology Department, Christchurch Hospital, Christchurch, New Zealand
    Cornea 23:776-80. 2004
    Traumatic globe rupture following penetrating keratoplasty is a life-long postoperative concern...
  29. doi New strategies for anterior cruciate ligament partial rupture using bone marrow transplantation in rats
    Kenichi Oe
    Department of Orthopaedic Surgery, Kansai Medical University, Moriguchi City, Osaka, Japan
    Stem Cells Dev 20:671-9. 2011
    ..intra-articular bone marrow transplantation using fresh whole BMCs is an effective treatment for ACL partial rupture. This therapy is easy to apply in a clinical setting because no culture system is required for collecting MSCs.
  30. ncbi Regulation of smooth muscle cell growth, function and death in vitro by activated mast cells--a potential mechanism for the weakening and rupture of atherosclerotic plaques
    Markus J Leskinen
    Wihuri Research Institute, Kalliolinnantie 4, FIN 00140 Helsinki, Finland
    Biochem Pharmacol 66:1493-8. 2003
    ..A thick cap protects the lipid-rich core, whereas a thin cap predisposes it to rupture, with ensuing acute clinical complications, such as myocardial infarction...
  31. doi Acute achilles tendon rupture: a randomized, controlled study comparing surgical and nonsurgical treatments using validated outcome measures
    Katarina Nilsson-Helander
    Katarina Nilsson Helander, Department of Orthopaedics, Kungsbacka Hospital, SE 434 40 Kungsbacka, Sweden
    Am J Sports Med 38:2186-93. 2010
    There is no consensus regarding the optimal treatment for patients with acute Achilles tendon rupture. Few randomized controlled studies have compared outcomes after surgical or nonsurgical treatment with both groups receiving early ..
  32. ncbi Diagnosis and management of bladder injury by trauma surgeons
    Chi Hsun Hsieh
    Department of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Kwei Shan, Taoyuan, Taiwan
    Am J Surg 184:143-7. 2002
    ..However, bladder injuries are usually associated with other major injuries, and it is our concern here how bladder injuries have been managed as part of multiple trauma...
  33. doi Major functional deficits persist 2 years after acute Achilles tendon rupture
    Nicklas Olsson
    Department of Orthopaedics, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Sweden
    Knee Surg Sports Traumatol Arthrosc 19:1385-93. 2011
    ..this prospective randomized controlled study was to evaluate the long-term results after an acute Achilles tendon rupture in patients treated surgically or non-surgically...
  34. ncbi Pectoralis major muscle injuries: evaluation and management
    Julio Petilon
    Naval Medical Center Portsmouth, Portsmouth, VA 23708, USA
    J Am Acad Orthop Surg 13:59-68. 2005
    ..Surgery, whether early or delayed, consistently yields superior results compared with nonsurgical management. Prompt diagnosis and timely intervention likely will produce improved results...
  35. ncbi A long-term study of anterior cruciate ligament allograft reconstruction
    K F Almqvist
    Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, Ghent University, De Pintelaan 185, 9000, Ghent, Belgium
    Knee Surg Sports Traumatol Arthrosc 17:818-22. 2009
    ..In conclusion, the tibialis anterior or tibialis posterior tendon allograft ACL reconstruction produced good clinical results in the majority of patients at long-term follow-up...
  36. ncbi Acute Achilles tendon rupture: minimally invasive surgery versus nonoperative treatment with immediate full weightbearing--a randomized controlled trial
    Roderick Metz
    Diakonessenhuis, Bosboomstraat 1, 3582 KE Utrecht, Netherlands
    Am J Sports Med 36:1688-94. 2008
    ..Surgical repair of acute Achilles tendon ruptures is considered superior to nonoperative treatment, but complications other than rerupture range up to 34%. Nonoperative treatment by functional bracing seems a promising alternative...
  37. ncbi The Achilles tendon Total Rupture Score (ATRS): development and validation
    Katarina Nilsson-Helander
    Lundberg Laboratory for Orthopaedic Research, Department of Orthopaedics, Sahlgrenska University Hospital, Goteborg University, Sweden
    Am J Sports Med 35:421-6. 2007
    There is a need for a patient-relevant instrument to evaluate outcome after treatment in patients with a total Achilles tendon rupture.
  38. ncbi [Surgical treatment of Achilles tendon rupture]
    M H Amlang
    Klinik fur Unfall und Wiederherstellungschirurgie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Fetscherstr 74, 01309, Dresden, Deutschland
    Unfallchirurg 113:712-20. 2010
    The open tendon suture is the most commonly used method of treatment for Achilles tendon rupture in Germany...
  39. pmc Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture
    Jacques Ohayon
    National Heart, Lung and Blood Institute, NIH, Bldg 10, 10 Center Dr, Bethesda, MD 20892, USA
    Am J Physiol Heart Circ Physiol 295:H717-27. 2008
    ..it remains unclear how these interact and affect peak cap stress (Cap(stress)), a known predictor of rupture. The aim of this study was to investigate the change in plaque vulnerability as a function of necrotic core size ..
  40. ncbi Rupture of the pectoralis major muscle
    Ville Aärimaa
    Department of Surgery, Turku University Hospital, Finland
    Am J Sports Med 32:1256-62. 2004
    Total or near-total rupture of the pectoralis major muscle is a rare injury. Fewer than 200 cases have been reported in literature, many of them in single case reports...
  41. ncbi Upregulation of fractalkine and its receptor, CX3CR1, is associated with coronary plaque rupture in patients with unstable angina pectoris
    Hideyuki Ikejima
    Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan
    Circ J 74:337-45. 2010
    ..and its cognate receptor, CX3CR1, play a role in atherogenesis, so the relationship between coronary plaque rupture, as observed by preintervention optical coherence tomography, and plasma levels of FKN and CX3CR1 was ..
  42. pmc Update on managing diaphragmatic rupture in blunt trauma: a review of 208 consecutive cases
    Talat Chughtai
    John and Liz Tory Regional Trauma Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ont
    Can J Surg 52:177-81. 2009
    Blunt diaphragmatic rupture (BDR) is a rare event and represents a diagnostic challenge...
  43. ncbi Increased content of type III collagen at the rupture site of human Achilles tendon
    Heidi A Eriksen
    Department of Clinical Chemistry, University of Oulu, P O Box 5000, FIN 90014, Oulu, Finland
    J Orthop Res 20:1352-7. 2002
    We compared the type I and III collagen amounts and cross-linked telopeptides at the rupture site and two other sites of the same tendon...
  44. ncbi Blunt tracheobronchial injuries: treatment and outcomes
    A C Kiser
    Department of Surgery, University of North Carolina School of Medicine, Chapel Hill 27599-7065, USA
    Ann Thorac Surg 71:2059-65. 2001
    ..We are also able to assess the mortality associated with the location and side of injury, examine the time from injury until diagnosis and treatment, and evaluate treatment outcome...
  45. pmc Coordinate regulation of IL-1beta and MMP-13 in rat tendons following subrupture fatigue damage
    Hui B Sun
    Leni and Peter May Department of Orthopaedics, Mount Sinai School of Medicine, 5 East 98th Street, 9th Floor, New York, NY 10029, USA
    Clin Orthop Relat Res 466:1555-61. 2008
    ..The data also suggest MMP-13 is regulated by both IL-1beta-dependent and IL-1beta-independent pathways...
  46. ncbi Effects of postoperative rehabilitation on limb function after cranial cruciate ligament repair in dogs
    Gregory S Marsolais
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA
    J Am Vet Med Assoc 220:1325-30. 2002
    ..To determine the effects of early postoperative rehabilitation on limb function in dogs after surgery for ruptured cranial cruciate ligament (RCCL)...
  47. doi Osteoarthritis in patients with anterior cruciate ligament rupture: a review of risk factors
    Hugues Louboutin
    Service de Chirurgie Orthopedique et Traumatologique, CHU Cavale Blanche Brest Cedex, France
    Knee 16:239-44. 2009
    ..factors for the development of osteoarthritis (OA) in patients who have had an anterior cruciate ligament (ACL) rupture are reviewed...
  48. ncbi CT cystography in the evaluation of major bladder trauma
    J P Vaccaro
    Department of Diagnostic Imaging, Brown University School of Medicine, Rhode Island Hospital, 593 Eddy St, Providence, RI 02903, USA
    Radiographics 20:1373-81. 2000
    ..In bladder contusion (type 1), findings are normal. In intraperitoneal rupture (type 2), CT cystography demonstrates intraperitoneal contrast material around bowel loops, between mesenteric ..
  49. ncbi Pathologic changes in grossly normal menisci in dogs with rupture of the cranial cruciate ligament
    J Jackson
    Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616, USA
    J Am Vet Med Assoc 218:1281-4. 2001
    ..To determine whether histopathologic changes are detectable in grossly normal medial menisci from dogs with rupture of the cranial cruciate ligament (CCL). DESIGN: Case series...
  50. ncbi Platelet concentrate injection improves Achilles tendon repair in rats
    Per Aspenberg
    Orthopedics and Sports Medicine, Department of Neuroscience and Locomotion, Faculty of Health Science, SE 581 85 Linkoping, Sweden
    Acta Orthop Scand 75:93-9. 2004
    ..Blood platelets release a cocktail of growth factors when activated, some of which are thought to initiate and stimulate repair...
  51. ncbi Consensus statement on bladder injuries
    Reynaldo G Gomez
    Department of Urology, Santiago, Chile
    BJU Int 94:27-32. 2004
  52. ncbi Pathology of the torn rotator cuff tendon. Reduction in potential for repair as tear size increases
    T J W Matthews
    Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford OX3 7LD, UK
    J Bone Joint Surg Br 88:489-95. 2006
    ..Tissue from large and massive tears is of such a degenerative nature that it may be a significant cause of re-rupture after surgical repair and could make healing improbable in this group.
  53. pmc Diagnostic ultrasound activation of contrast agent gas bodies induces capillary rupture in mice
    D L Miller
    Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 97:10179-84. 2000
    ..hemorrhages (PHs) in intestine and abdominal muscle were counted 15 min after exposure to characterize capillary rupture, and Evans blue extravasation was evaluated in samples of muscle tissue...
  54. ncbi The risk of anterior cruciate ligament rupture with generalised joint laxity
    R Ramesh
    Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter Hospital NHS Trust Wonford, Barrack Road, Exeter EX2 5DW, UK
    J Bone Joint Surg Br 87:800-3. 2005
    ..Statistical analysis showed a significant correlation for these associations. We conclude that anterior cruciate ligament injury is more common in those with joint laxity and particularly so for those with hyperextension of the knee...
  55. doi Tracheal rupture after endotracheal intubation: a literature systematic review
    Eduardo Minambres
    Service of Intensive Care, Marques de Valdecilla University Hospital, Santander 39008, Spain
    Eur J Cardiothorac Surg 35:1056-62. 2009
    We aim to perform a systematic review and meta-analysis of the cases of postintubation tracheal rupture (PiTR) published in the literature, with the aim of determining the risk factors that contribute to tracheal rupture during ..
  56. ncbi Is percutaneous repair of the Achilles tendon a safe technique? A study of 124 cases
    Renaud Maes
    Clinique Louis Caty, Baudour, Belgium
    Acta Orthop Belg 72:179-83. 2006
    Ma and Griffith first described in 1977 a percutaneous technique for the repair of acute Achilles tendon rupture. In 1992, Delponte popularised a new percutaneous technique with Tenolig...
  57. ncbi Intraarticular rupture pattern of the ACL
    Thore Zantop
    Department of Trauma, Hand and Reconstructive Surgery, Wilhelms University Muenster, Germany
    Clin Orthop Relat Res 454:48-53. 2007
    To date, the intraarticular rupture pattern of the anterior cruciate ligament (ACL) has not been reported...
  58. ncbi Animal model that mimics atherosclerotic plaque rupture
    M D Rekhter
    Department of Vascular and Cardiac Diseases, Parke Davis Pharmaceutical Research Division, Warner Lambert Company, Ann Arbor, MI 48105, USA
    Circ Res 83:705-13. 1998
    Atherosclerotic plaque rupture is the main cause of coronary thrombosis and myocardial infarcts. Currently, there is no animal model of plaque disruption...
  59. ncbi Long-term follow-up after primary repair of the anterior cruciate ligament: clinical and radiological evaluation 15-23 years postoperatively
    T Strand
    Department of Orthopaedic Surgery, Diakonissehjemmets sykehus, 5009 Bergen, Norway
    Arch Orthop Trauma Surg 125:217-21. 2005
    ..We have previously reported results after 2-5 and 5-10 years follow-up of repair of acute anterior cruciate ligament (ACL) ruptures by suturing. Reports of results after more than 10 years are rare...
  60. doi Late presentation of blunt right diaphragmatic rupture (hepatic hernia)
    Orhan Kozak
    Department of General Surgery, Gulhane Military Medical Academy, Ankara, Turkey
    Am J Emerg Med 26:638.e3-5. 2008
    Diaphragmatic rupture occurs in 0.8% to 3.6% of patients after blunt or penetrating thoracoabdominal trauma, and the preoperative diagnosis is difficult...
  61. ncbi Long-term outcome of operative or nonoperative treatment of anterior cruciate ligament rupture--is sports activity a determining variable?
    C Fink
    University Hospital for Traumatology, Innsbruck, Austria
    Int J Sports Med 22:304-9. 2001
    ..Sports activity represents an important variable not only affecting the outcome, but also influencing treatment decisions following ACL injuries...
  62. pmc Proximal biceps rupture: management of an unusual injury in an arm wrestler
    D A Pratt
    Department of Trauma and Orthopaedics, St George s Hospital NHS Trust, London, UK
    Br J Sports Med 41:459. 2007
    ..The diagnosis and treatment of a 36-year-old man who sustained a proximal biceps rupture while arm wrestling and his operative management are described.
  63. ncbi Neglected ruptures of the Achilles tendon
    Hamish D H Leslie
    Orthopaedic Foot and Ankle Centre of Victoria, Level 1, Victoria House, 316 324 Malvern Road, Prahran, Victoria, 3181 Australia
    Foot Ankle Clin 10:357-70. 2005
    ..The optimal management is surgical. Many different techniques can be used to repair or reconstruct the rupture, including tendo-Achilles advancement or flap reconstruction; local tendon transfer; and autologous, autograft, ..
  64. pmc Delayed presentation of internal mammary artery rupture after blunt chest trauma: characteristic CT and plain x ray findings
    O Y Kwon
    Department of Anatomy, College of Medicine, Chungnam National University, Daejeon, Republic of Korea corrected
    Emerg Med J 22:664-5. 2005
  65. ncbi Morphology of exertion-triggered plaque rupture in patients with acute coronary syndrome: an optical coherence tomography study
    Atsushi Tanaka
    Department of Cardiovascular Medicine, Wakayama Medical University, Kimiidera, Wakayama, Japan
    Circulation 118:2368-73. 2008
    Plaque rupture and secondary thrombus formation play key roles in the onset of acute coronary syndrome (ACS)...
  66. ncbi Permanent disabilities in the displaced muscle from rupture of the long head tendon of the biceps
    Søren R Deutch
    Orthopaedic Department E, Aarhus University Hospital, Denmark
    Scand J Med Sci Sports 15:159-62. 2005
    Patients with a displaced muscle belly because of rupture of the long head biceps tendon were investigated for local pain and other disabilities, together with strength and endurance loss...
  67. ncbi Rupture of the distal biceps brachii tendon: conservative treatment versus anatomic reinsertion--clinical and radiological evaluation after 2 years
    Claudio Chillemi
    Istituto Chirurgico Ortopedico Traumatologico, Via del Lido, 110, 04100 Latina, Italy
    Arch Orthop Trauma Surg 127:705-8. 2007
    Distal biceps tendon rupture is a relatively rare injury...
  68. ncbi Laparoscopic repair in intraperitoneal rupture of urinary bladder in blunt trauma abdomen
    Ashish Bhanot
    Department of Surgery, Government Medical College, Bhavnagar, India
    Surg Laparosc Endosc Percutan Tech 17:58-9. 2007
    Intraperitoneal rupture of urinary bladder is a common condition associated with pelvic fractures. This is a true surgical emergency managed conventionally by open laparotomy with single layer or double layer repair...
  69. ncbi Acute rupture of achilles tendon in a 7-year-old girl
    Mark Eidelman
    Pediatric Orthopedics Unit, Rambam Medical Center, Haifa, Israel
    J Pediatr Orthop B 13:32-3. 2004
    ..In children, rupture of the tendon is usually due to avulsion of the tendon from the calcaneus but not within the tendon itself...
  70. ncbi Gluteus tendon rupture is underrecognized by French orthopedic surgeons: results of a mail survey
    Grégoire Cormier
    Rheumatology Department, Nantes Teaching Hospital, 44093 Nantes Cedex 1, France
    Joint Bone Spine 73:411-3. 2006
    ..To obtain information on the diagnosis and surgical treatment of hip rotator cuff tears by French orthopedic surgeons...
  71. doi Simultaneous uterine and urinary bladder rupture in an otherwise successful vaginal birth after cesarean delivery
    Szu Ying Ho
    Department of Obstetrics and Gynecology, Hsinchu Cathay General Hospital, Hsinchu, Taiwan, R O C
    J Chin Med Assoc 73:655-9. 2010
    Uterine rupture is the primary concern when a patient chooses a trial of labor after a cesarean section. Bladder rupture accompanied by uterine rupture should be taken into consideration if gross hematuria occurs...
  72. doi A biomechanical comparison of the primary stability of two minimally invasive techniques for repair of ruptured Achilles tendon
    Umile Giuseppe Longo
    Department of Orthopaedic and Trauma Surgery, Campus Bio Medico University, Via Alvaro del Portillo, 200, 00128, Rome, Italy
    Knee Surg Sports Traumatol Arthrosc 20:1392-7. 2012
    ..To compare the primary stability of two minimally invasive procedures of Achilles tendon (AT) repair, namely a modified percutaneous repair of ruptured AT and the Achillon suture configuration...
  73. ncbi Surgical treatment of distal biceps rupture
    Karen M Sutton
    Department of Othopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT, USA
    J Am Acad Orthop Surg 18:139-48. 2010
    b>Rupture of the distal biceps tendon accounts for 10% of all biceps brachii ruptures. Injuries typically occur in the dominant elbow of men aged 40 to 49 years during eccentric contraction of the biceps...
  74. ncbi Operative and functional treatment of rupture of the lateral ligament of the ankle. A randomised, prospective trial
    A C M Pijnenburg
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, Amsterdam, The Netherlands
    J Bone Joint Surg Br 85:525-30. 2003
    Consecutive patients with a confirmed rupture of at least one of the lateral ligaments of the ankle were randomly assigned to receive either operative or functional treatment. They were evaluated at a median of 8 years (6 to 11)...
  75. pmc Incidence of deep vein thrombosis and pulmonary embolism after Achilles tendon rupture
    Arush Patel
    Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, 1520 San Pablo St Suite 2000, Los Angeles, CA 90033, USA
    Clin Orthop Relat Res 470:270-4. 2012
    The use of venous thromboembolism prophylaxis after an Achilles rupture is controversial. The rates of reported deep vein thrombosis (DVT) range from 6.3% to 34%...
  76. ncbi Biomechanical analysis of an ovine rotator cuff repair via porous patch augmentation in a chronic rupture model
    Brandon G Santoni
    Department of Mechanical Engineering and School of Biomedical Engineering, Colorado State University, Fort Collins, CO 80523 1374, USA
    Am J Sports Med 38:679-86. 2010
    ..Nonresorbable implants provide an appealing approach because patch materials may confer acute mechanical stability and act as a conductive scaffold for tissue ingrowth at the site of the tendon insertion...
  77. ncbi Rupture of latissimus dorsi in an athlete
    Dale J Butterwick
    Sport Medicine Centre, Faculty of Kinesiology, University of Calgary, Alberta, Canada
    Clin J Sport Med 13:189-91. 2003
  78. ncbi Delayed rupture of flexor pollicis longus tendon after volar plating of the distal radius
    Siu Cheong Koo
    Department of Orthopaedic and Traumatology, Caritus Medical Centre, Kowloon, Hong Kong S A R, China
    Hand Surg 11:67-70. 2006
    Flexor tendon rupture following distal radius fracture is rare. We described a case of flexor pollicis longus rupture, presented five years after volar plating of distal radius fracture.
  79. pmc Validation of two scoring systems for the prediction of posterior capsule rupture during phacoemulsification surgery
    S A Osborne
    Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland SR2 9HP, UK
    Br J Ophthalmol 90:333-6. 2006
    ..To attempt to validate two scoring systems for the prediction of intraoperative complication during phacoemulsification surgery...
  80. ncbi [Effects of round window membrane rupture on cochlear blood flow and endocochlear potential]
    Xiuli Liu
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya
    Nihon Jibiinkoka Gakkai Kaiho 106:723-9. 2003
    ..the effect of perilymphatic fistula on cochlear function, we studied the effect of round window membrane rupture on cochlear blood flow (CBF) by placing a laser-Doppler probe to the basal turn in 20 guinea pigs...
  81. doi Concurrent bilateral patellar tendon rupture in a preadolescent athlete: a case report and review of the literature
    Jung Ryul Kim
    Department of Orthopaedic Surgery, Chonbuk National University Medical School, Jeonju, Korea
    J Pediatr Orthop B 19:511-4. 2010
    Concurrent bilateral patellar tendon rupture in preadolescence is a very rare condition. It is mostly associated with systemic disease or steroid use in adults...
  82. ncbi Spontaneous rupture of the Achilles tendon is preceded by widespread and bilateral tendon damage and ipsilateral inflammation: a clinical and histopathologic study of 60 patients
    Rene Cetti
    Department of Orthopaedic Surgery, Bispebjerg University Hospital, Copenhagen, Denmark
    Acta Orthop Scand 74:78-84. 2003
    60 consecutive patients with spontaneous rupture of the Achilles tendon (AT) underwent surgery...
  83. doi Tibiofemoral contact pressures and osteochondral microtrauma during anterior cruciate ligament rupture due to excessive compressive loading and internal torque of the human knee
    Eric G Meyer
    Orthopaedic Biomechanics Laboratories, Michigan State University, East Lansing, Michigan 48824, USA
    Am J Sports Med 36:1966-77. 2008
    ..Bone bruises are seen in over 80% of patients with ACL injuries, and have been associated with an overt loss of cartilage overlying those regions within 6 months of injury...
  84. ncbi Intravitreal bevacizumab injection in patients with choroidal neovascularization due to choroid rupture after blunt-head trauma
    Ozgur Artunay
    Department of Ophthalmology, Istanbul Science University, Istanbul, Turkey
    Int Ophthalmol 29:289-91. 2009
    To describe and report the effect of intravitreal bevacizumab (Avastin) as primary treatment for secondary choroidal neovascularization (CNV) after choroidal rupture due to blunt-head trauma.
  85. ncbi [Traumatic rupture of the diaphragm: diagnostic considerations, prognostic factors, outcomes]
    S Lunca
    Universitatea de Medicină si Farmacie Gr T Popa Iaşi, Clinica de Chirurgie Urgente, Facultatea de Medicină Spitalul Clinic de Urgenţe Iaşi
    Rev Med Chir Soc Med Nat Iasi 111:416-22. 2007
    Diaphragmatic rupture remains a diagnostic challenge because of the lack of an accurate test demonstrating the injury.
  86. doi Comparison of tibial plateau angles in dogs with unilateral versus bilateral cranial cruciate ligament rupture: 150 cases (2000-2006)
    Sady Y Cabrera
    Department of Surgery, VCA West Los Angeles Animal Hospital, 1818 S Sepulveda Blvd, Los Angeles, CA 90025, USA
    J Am Vet Med Assoc 232:889-92. 2008
    To compare tibial plateau angle (TPA) in dogs with unilateral versus bilateral cranial cruciate ligament (CCL) rupture, to compare right versus left TPA in dogs with bilateral CCL rupture, and to determine whether TPA can be used to ..
  87. ncbi [Traumatic diaphragmatic rupture: results of the chest surgery clinic]
    Irfan Yalcinkaya
    4th Thoracic Surgery Clinic, Sureyyapasa Thoracic and Cardiovascular Diseases Training and Research Hospital, Istanbul, Turkey
    Ulus Travma Acil Cerrahi Derg 14:221-5. 2008
    Traumatic diaphragmatic rupture is an urgent and life-threatening condition concerning the branches of chest surgery and general surgery because of the accompanying injuries...
  88. ncbi Traumatic rupture of the ligamentum teres as a source of hip pain
    Michael Wettstein
    Arthroscopy 21:382; author reply 383. 2005
  89. ncbi Elbow joint laxity after experimental radial head excision and lateral collateral ligament rupture: efficacy of prosthetic replacement and ligament repair
    Steen Lund Jensen
    Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark
    J Shoulder Elbow Surg 14:78-84. 2005
    ..The combination of LCL repair and radial head replacement restores laxity completely, but an isolated LCL repair performs almost as well, probably by compensating for the ligamentous tension lost from radial head excision...
  90. ncbi Detection of DNA from a range of bacterial species in the knee joints of dogs with inflammatory knee arthritis and associated degenerative anterior cruciate ligament rupture
    Peter Muir
    Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53706, USA
    Microb Pathog 42:47-55. 2007
    ..common inflammatory knee arthritis in which associated pathological degenerative anterior cruciate ligament (ACL) rupture often develops were studied...
  91. ncbi [Conservative versus operative treatment after ACL-rupture: influence on the muscle strength capability of the lower extremity]
    K Karanikas
    Institut für Biomechanik und Orthopädie Deutsche Sporthochschule Köln
    Sportverletz Sportschaden 19:15-21. 2005
    In this study two groups of ACL-rupture patients having had a conservative or an operative treatment and a similar rehabilitation were compared regarding their muscle strength capabilities, and the clinical outcome.
  92. ncbi Ultrasound diagnosis of quadriceps tendon rupture
    Brian G LaRocco
    Department of Emergency Medicine, Christiana Care Health Services, Newark, Delaware, USA
    J Emerg Med 35:293-5. 2008
    ..A case report of bilateral quadriceps tendon rupture is presented demonstrating the utility and ease of bedside ultrasound to rapidly confirm the diagnosis.
  93. doi Use of stent grafts and coils in vessel rupture and perforation
    Khung Keong Yeo
    Division of Cardiovascular Medicine, University of California, Davis Medical Center, Sacramento, California, USA
    J Interv Cardiol 21:86-99. 2008
    Vessel rupture and perforation are important complications of percutaneous treatment of coronary and peripheral arterial disease...
  94. ncbi [Traumatic rupture of the diaphragm]
    J Cerón Navarro
    Servicio de Cirugía Torácica, Hospital Universitario La Fe, Valencia, Espana
    Arch Bronconeumol 44:197-203. 2008
    Traumatic rupture of the diaphragm (TRD) is a rare occurrence, with variable morbidity and mortality. The aim of this study was to analyze cases of TRD in a tertiary hospital and assess prognostic factors associated with mortality.
  95. ncbi Inheritance of rupture of the cranial cruciate ligament in Newfoundlands
    Vicki L Wilke
    Department of Animal Sciences, Center for Integrated Animal Genomics, Iowa State University, Ames, IA 50011 1250, USA
    J Am Vet Med Assoc 228:61-4. 2006
    To determine prevalence, level of inbreeding, heritability, and mode of inheritance for rupture of the cranial cruciate ligament (RCCL) in Newfoundlands.
  96. ncbi Rupture of the superficial dorsal vein of the penis
    Gyanendra R Sharma
    Solapur Kidney Care and Research Center Pvt Ltd, Urology, Solapur, Maharashtra, India
    Int J Urol 12:1071-3. 2005
    Unusual causes of acute penis, such as the rupture of a superficial vein of the penis, can mimic fractured penis. The diagnosis in such cases is mostly after exploration...
  97. doi Operative versus nonoperative treatment of anterior cruciate ligament rupture in patients aged 40 years or older: an expected-value decision analysis
    Khemarin Seng
    Taos Orthopaedic Institute Research Foundation, Taos, New Mexico 87571, USA
    Arthroscopy 24:914-20. 2008
    Our purpose was to determine the optimal treatment of anterior cruciate ligament (ACL) rupture in patients aged 40 years or older.
  98. ncbi Risk factors associated with the rupture of tubal ectopic pregnancy
    Gregory Latchaw
    Department of Obstetrics and Gynecology, Jackson Memorial Hospital University of Miami, Miami, FL 33010, USA
    Gynecol Obstet Invest 60:177-80. 2005
    To identify risk factors that may lead to the rupture of ectopic pregnancies.
  99. pmc Rupture of the pectoralis major muscle: surgical treatment in athletes
    R G Kakwani
    Good Hope Hospital, Birmingham, B75 7RR, UK
    Int Orthop 31:159-63. 2007
    Pectoralis major tendon rupture is a relatively rare injury, resulting from violent, eccentric contraction of the muscle. Over 50% of these injuries occur in athletes, classically in weight-lifters during the 'bench press' manoeuvre...
  100. ncbi Diagnosis of blunt bladder injury: A prospective comparative study of computed tomography cystography and conventional retrograde cystography
    Peter V Quagliano
    Department of Radiology, McGuire Veterans Medical Center, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23249, USA
    J Trauma 61:410-21; discussion 421-2. 2006
    ..to evaluate prospectively the accuracy of computed tomography (CT) cystography for the detection of bladder rupture, performed concurrently with screening abdominal/pelvic CT, in patients at risk for blunt bladder injury...
  101. doi Severe brain injury with rupture of the superior sagittal sinus after vacuum extraction birth
    Christian Musahl
    Neurosurgery, Wedau Kliniken, Duisburg, Germany
    J Neurosurg Pediatr 1:471-3. 2008
    ..The authors present a case of severe brain damage with rupture of the sinus after vacuum extraction delivery for which surgical repair of the dural tear and brain prolapse was ..

Research Grants135 found, 100 shown here

  1. Serpin Modulation of Inflammatory Vasculitis; Potential for Immunomodulatory Ther
    ALEXANDRA ROSE LUCAS; Fiscal Year: 2010
    ..formation, manifesting as sudden loss of vision, stroke, myocardial ischemia, aortic arch syndrome, and aneurysm rupture. Once diagnosed, the IVS are considered medical emergencies...
  2. Serpin Modulation of Inflammatory Vasculitis; Potential for Immunomodulatory Ther
    Alexandra Lucas; Fiscal Year: 2009
    ..formation, manifesting as sudden loss of vision, stroke, myocardial ischemia, aortic arch syndrome, and aneurysm rupture. Once diagnosed, the IVS are considered medical emergencies...
  3. CFI Pathogen Inactivation Technology
    Trevor P Castor; Fiscal Year: 2010
    ..The overfilled particles are then decompressed and, as a result of rapid phase conversion, rupture at their weakest points...
  4. CFI Pathogen Inactivation Technology
    TREVOR CASTOR; Fiscal Year: 2009
    ..The overfilled particles are then decompressed and, as a result of rapid phase conversion, rupture at their weakest points...
  5. Comprehensive biomarker study to capitalize on existing GWAS in 10K South Asians
    Daniel Rader; Fiscal Year: 2009
    ..biochemical dimension to PROMIS by assaying plasma biomarkers potentially relevant to atherogenesis, plaque rupture and/or thrombosis...
  6. Comprehensive biomarker study to capitalize on existing GWAS in 10K South Asians
    Danish Saleheen; Fiscal Year: 2010
    ..biochemical dimension to PROMIS by assaying plasma biomarkers potentially relevant to atherogenesis, plaque rupture and/or thrombosis...
  7. Roles of Nitric Oxide and Superoxide in Cystitis
    ANTHONY JOHN KANAI; Fiscal Year: 2013
    ..This leads to swelling and rupture of the mitochondria, cytochrome c release and apoptosis. We developed a mitochondrial targeting strategy (U.S...
  8. C5a as an Anti-HIV Microbicidal Candidate
    PHILIPPE ANDRE GALLAY; Fiscal Year: 2010
    ..The HIV membrane rupture is specific because C5A does not disturb the integrity of the plasma membrane of human cells even when used at ..
  9. C5a as an Anti-HIV Microbicidal Candidate
    PHILIPPE ANDRE GALLAY; Fiscal Year: 2013
    ..The HIV membrane rupture is specific because C5A does not disturb the integrity of the plasma membrane of human cells even when used at ..
  10. Inflammation and Cerebral Aneurysm Formation: Targets for Modulation and Vascular
    Brian L Hoh; Fiscal Year: 2010
    ..The rationale for the proposed research is that because cerebral aneurysms can be diagnosed before they rupture, a therapy that would repair the aneurysm inflammatory process and prevent aneurysms from progressing to rupture, ..
  11. Harness Germinal Matrix Hemorrhage
    John H Zhang; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Germinal matrix hemorrhage (GMH) is defined as the rupture of immature blood vessels within the subependymal brain tissue. Occurring in approximately 3...
  12. Development of a Porcine Model of Atherosclerosis
    Christopher Rogers; Fiscal Year: 2010
    ..These plaques often rupture, causing myocardial infarction, stroke, or death...
  13. Novel Biomarkers in Aortic Aneurysms and Acute Aortic Dissection
    Jennifer Van Eyk; Fiscal Year: 2009
    ..and specific Change Topic, 06- HL-101 "Developing technologies for assessment of aortic aneurysms prone to rupture or dissection". Aortic dissection describes a tear in the wall of the main vessel in the body, the aorta...
  14. Novel Biomarkers in Aortic Aneurysms and Acute Aortic Dissection
    JENNIFER E contact VAN EYK; Fiscal Year: 2010
    ..and specific Change Topic, 06- HL-101 "Developing technologies for assessment of aortic aneurysms prone to rupture or dissection". Aortic dissection describes a tear in the wall of the main vessel in the body, the aorta...
  15. Leukemia Inhibitory Factor As a Mediator of Primate Ovulation &Oocyte Maturation
    Jon D Hennebold; Fiscal Year: 2012
    ..Such mRNAs are likely involved in activities necessary for follicle rupture, which include the formation of a hyaluronan-rich extracellular matrix between cumulus cells and the loss of ..
  16. EEG Synchrony, perinatal risk and outcome: analysis of CHIME data
    PHILIP GEORGE GRIEVE; Fiscal Year: 2010
    ..and abuse and, in some cases, mode of delivery;2) intra-partum factors such as presence and duration of labor and rupture of membranes, chorioamnionitis, antenatal corticosteroids, and mode of delivery;and 3) postnatal factors such as ..
  17. NICHD Maternal Fetal Medicine Units Network
    Geeta K Swamy; Fiscal Year: 2013
    ..Content expertise includes prematurity, premature rupture of membranes, fetal growth restriction, racial disparities, maternal immunization, and maternal medical ..
  18. Atherogenic mechanism of lipid peroxidation-derived aldehydes
    Sanjay Srivastava; Fiscal Year: 2013
    ..the mechanisms by which these lipids or their products induce vascular injury, and promote plaque formation or rupture are unknown...
  19. Atherogenic mechanism of lipid peroxidation-derived aldehydes
    Sanjay Srivastava; Fiscal Year: 2010
    ..the mechanisms by which these lipids or their products induce vascular injury, and promote plaque formation or rupture are unknown...
  20. Tissue Factor &Clot Formation In Abdominal Aortic Aneurysm
    ALBERT PHILLIP OWENS; Fiscal Year: 2013
    ..inflammatory disease of the aorta that can result in dissection of the wall, formation of an intramural clot, and rupture of th aorta resulting in almost immediate death in the majority of cases...
  21. PRESSURE REGULATION OF HUMAN TRABECULAR MESHWORK GENES
    TERESA BORRAS; Fiscal Year: 2010
    ..decreases elasticity of the blood vessels and increases their brittleness, leading to increase risk of arterial rupture. In this project we aim to characterize this process in the eye of transgenic animals, human eyes from post-..
  22. Harness Germinal Matrix Hemorrhage
    John H Zhang; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Germinal matrix hemorrhage (GMH) is defined as the rupture of immature blood vessels within the subependymal brain tissue. Occurring in approximately 3...
  23. Peripheral blood dendritic cells and periodontitis
    CHRISTOPHER WILLIAM CUTLER; Fiscal Year: 2011
    ..These DCs express specific atherogenic biomarkers that can promote plaque rupture, thrombus formation, and increase risk of heart attack and stroke...
  24. Retinal Imaging of Prognostic Indicators of Atherosclerosis
    Frederick R Haselton; Fiscal Year: 2010
    ..involving multiple cell types and proteins in various stages of initiation, progression, and eventually plaque rupture which is responsible for mortality and morbidity...
  25. Regulatory Mechanisms of Oxidative Stress in Cardiac Angiogenesis Postinfarction
    Yao Sun; Fiscal Year: 2010
    ..Impaired angiogenesis in the infarcted heart can lead to rupture and immature/weakened scar tissue...
  26. Methionine sulfoxide reductase A and oxidized CaMKII in structural heart disease
    Mark E Anderson; Fiscal Year: 2011
    ..Aim 1 Determine how Aldo and ox-CaMKII promote cardiac rupture after MI...
  27. Inflammation and Cerebral Aneurysm Formation: Targets for Modulation and Vascular
    BRIAN LIM HOH; Fiscal Year: 2013
    ..The rationale for the proposed research is that because cerebral aneurysms can be diagnosed before they rupture, a therapy that would repair the aneurysm inflammatory process and prevent aneurysms from progressing to rupture, ..
  28. Antioxidant Status, Diet, and Early Pregnancy
    Marlene Goldman; Fiscal Year: 2009
    ..reactive oxygen species (ROS) have been associated with spontaneous abortion, preeclampsia, and premature preterm rupture of the membranes in women and defective sperm function in men...
  29. MECHANISMS OF FETAL MEMBRANE RUPTURE
    JEROME STRAUSS; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Preterm premature rupture of the fetal membranes (PPROM) is a major cause of maternal morbidity and premature birth...
  30. Molecular Imaging Probes for Reporting on Vascular Oxidative Response
    Alexei A Bogdanov; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: Diseased blood vessel walls frequently develop lesions that can become unstable and rupture. The rupture leads to blocking blood supply and death of tissues in the brain and heart and may result in ..
  31. Regulatory Mechanisms of Oxidative Stress in Cardiac Angiogenesis Postinfarction
    Yao Sun; Fiscal Year: 2013
    ..Impaired angiogenesis in the infarcted heart can lead to rupture and immature/weakened scar tissue...
  32. Development of New Molecular Probes for Diagnostic Imaging of Atherosclerosis
    KAREN CATHERIN BRILEY SAEBO; Fiscal Year: 2010
    ..target oxidization-specific epitopes, present on oxLDL, may enable early in vivo detection of plaque prone to rupture. We have reported that oxLDL targeted gadolinium (Gd) micelles may be used for in vivo MR detection of oxidation-..
  33. The Role of Interleukin-2 in Vascular Smooth Muscle Cell Homeostasis
    Lucile E Wrenshall; Fiscal Year: 2010
    ..in neointimal hyperplasia, and apoptosis of VSMCs is involved in aneurysm formation and atherosclerotic plaque rupture, much information has yet to be learned about how SMC proliferation is controlled in vivo and how said control ..
  34. Leukemia Inhibitory Factor As a Mediator of Primate Ovulation &Oocyte Maturation
    Jon D Hennebold; Fiscal Year: 2013
    ..Such mRNAs are likely involved in activities necessary for follicle rupture, which include the formation of a hyaluronan-rich extracellular matrix between cumulus cells and the loss of ..
  35. Calcification and Vascular Cell Differentiation
    Cecilia M Giachelli; Fiscal Year: 2013
    ..It leads to cardiac valve stenosis, increased pulse pressure, hypertension and may contribute to plaque rupture, all of which can lead to heart failure...
  36. Cthrc1 function as a novel TGF-beta antagonist in the vasculature
    Volkhard Lindner; Fiscal Year: 2012
    ..In many tissues of affected mice, bleeding is observed that appears to be caused by rupture of malformed vessels. Thus Cthrc1 is an essential molecule with partial penetrance of lethal haploinsufficiency...
  37. Cthrc1 function as a novel TGF-beta antagonist in the vasculature
    Volkhard Lindner; Fiscal Year: 2013
    ..In many tissues of affected mice, bleeding is observed that appears to be caused by rupture of malformed vessels. Thus Cthrc1 is an essential molecule with partial penetrance of lethal haploinsufficiency...
  38. MECHANISMS OF FETAL MEMBRANE RUPTURE
    Jerome F Strauss; Fiscal Year: 2010
    Preterm premature rupture of the fetal membranes (PPROM) is a major cause of maternal morbidity and premature birth...
  39. Chronic imaging of cellular dynamics after cortical microhemorrhage
    Chris B Schaffer; Fiscal Year: 2013
    ..In recent work, we used a novel laser-based approach to rupture targeted arterioles in the brain of mice and imaged the impact of these lesions using two-photon microscopy...
  40. CFI Inactivation of Human Plasma
    TREVOR CASTOR; Fiscal Year: 2009
    ..The overfilled particles are then decompressed and, as a result of rapid phase conversion, rupture at their weakest points...
  41. Mechanism and Inhibition of Collagenolytic Activity
    Gregg B Fields; Fiscal Year: 2010
    ..states plays a role in tumor growth and invasion, cartilage degradation, or atherosclerotic plaque formation and rupture. Only a small number of proteases have been identified capable of efficient processing of triple-helical regions ..
  42. Development of Experimental and Computational Models for Traumatic Aortic Rupture
    Kurosh Darvish; Fiscal Year: 2009
    Traumatic Aortic Rupture (TAR) is a leading cause of fatality in motor vehicle accidents. About 20 percent of fatalities in motor vehicle crashes are caused by aortic injuries...
  43. RHESUS PROPAGATION BY INTRACYTOPLASMIC NUCLEAR INJECTION (SUPPLEMENT)
    Gerald Schatten; Fiscal Year: 2000
    ..Studies currently focus on whether P mediates LH actions leading to rupture and luteinization of the follicle...
  44. Inflammation and Cerebral Aneurysm Formation: Targets for Modulation and Vascular
    Brian Hoh; Fiscal Year: 2009
    ..The rationale for the proposed research is that because cerebral aneurysms can be diagnosed before they rupture, a therapy that would repair the aneurysm inflammatory process and prevent aneurysms from progressing to rupture, ..
  45. Drug-Eluting Bioresorbable Polymer Scaffolding for Treatment of Aortic Aneurysms
    Jack Griffis; Fiscal Year: 2009
    ..The aneurysm weakens the wall of the aorta and can result in rupture. Because the volume of blood flowing through the aorta is under relatively high pressure, a rupture can be ..
  46. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASMS
    Bryce Weir; Fiscal Year: 1993
    About 30,000 North Americans have rupture of an intracranial aneurysm each year...
  47. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASMS
    Bryce Weir; Fiscal Year: 1992
    About 30,000 North Americans have rupture of an intracranial aneurysm each year...
  48. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASMS
    Bryce Weir; Fiscal Year: 1991
    About 30,000 North Americans have rupture of an intracranial aneurysm each year...
  49. Use Of Adipose Derived Stem Cells For Engineering Of Ligament Tissue
    David McAllister; Fiscal Year: 2009
    Abstract: Rupture of the anterior cruciate ligament (ACL) is one of most common ligament injuries of the knee and is often seen in the VA patient population...
  50. Bioengineering Studies of Abdominal Aortic Aneurysm Fluid and Wall Dynamics
    ENDER FINOL; Fiscal Year: 2009
    ..investigate the central hypothesis that, once an aneurysm is diagnosed, the primary biomechanical determinant of rupture potential is the non-uniform arterial wall thickness, within the context of a dynamic assessment of aneurysm ..
  51. Endothelin-2 in Ovarian Follicle Rupture
    Chemyong Ko; Fiscal Year: 2009
    The goal of the proposed studies is to elucidate the mechanism of endothelin-2 (EDN-2) action in follicle rupture. The program of ovulation is activated by a surge of luteinizing hormone, which initiates dramatic changes in molecular, ..
  52. Endothelin-2 in Ovarian Follicle Rupture
    Chemyong Ko; Fiscal Year: 2007
    ..The goal of the proposed studies is to elucidate the mechanism of endothelin-2 (EDN-2) action in follicle rupture. The program of ovulation is activated by a surge of luteinizing hormone, which initiates dramatic changes in ..
  53. Endothelin-2 in Ovarian Follicle Rupture
    Chemyong Ko; Fiscal Year: 2006
    ..The goal of the proposed studies is to elucidate the mechanism of endothelin-2 (EDN-2) action in follicle rupture. The program of ovulation is activated by a surge of luteinizing hormone, which initiates dramatic changes in ..
  54. Endothelin-2 in Ovarian Follicle Rupture
    Chemyong Ko; Fiscal Year: 2010
    The goal of the proposed studies is to elucidate the mechanism of endothelin-2 (EDN-2) action in follicle rupture. The program of ovulation is activated by a surge of luteinizing hormone, which initiates dramatic changes in molecular, ..
  55. COMPLICATIONS OF CHLAMYDIAL INFECTION IN PREGNANCY
    H Harrison; Fiscal Year: 1980
    ..trachomatis during pregnancy. We wish to determine whether amnionitis, premature rupture of membranes, and post-partum endometritis are associated with maternal chlamydial infection...
  56. Cues for cell-mediated regeneration of elastin matrix to stabilize aortic aneurys
    Anand Ramamurthi; Fiscal Year: 2010
    ..aortic aneurysms (AAAs), characterized by degrading aortic elastin matrix and resultant vessel weakening and rupture, causes 15,000 deaths in the United States anually, primarily amongst seniors, and those suffering from inherited ..
  57. Cues for cell-mediated regeneration of elastin matrix to stabilize aortic aneurys
    Anand Ramamurthi; Fiscal Year: 2009
    ..aortic aneurysms (AAAs), characterized by degrading aortic elastin matrix and resultant vessel weakening and rupture, causes 15,000 deaths in the United States anually, primarily amongst seniors, and those suffering from inherited ..
  58. Cues for cell-mediated regeneration of elastin matrix to stabilize aortic aneurys
    Anand Ramamurthi; Fiscal Year: 2009
    ..aortic aneurysms (AAAs), characterized by degrading aortic elastin matrix and resultant vessel weakening and rupture, causes 15,000 deaths in the United States anually, primarily amongst seniors, and those suffering from inherited ..
  59. Cues for cell-mediated regeneration of elastin matrix to stabilize aortic aneurys
    Anand Ramamurthi; Fiscal Year: 2010
    ..aortic aneurysms (AAAs), characterized by degrading aortic elastin matrix and resultant vessel weakening and rupture, causes 15,000 deaths in the United States anually, primarily amongst seniors, and those suffering from inherited ..
  60. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASM
    Bryce Weir; Fiscal Year: 1999
    b>Rupture of an intracranial aneurysm, causing subarachnoid hemorrhage (SAH), afflicts about 30,000 North Americans per year...
  61. A THECAL ROLE IN OVULATION
    KATHERINE ROBY; Fiscal Year: 1999
    Ovulation has been described as a pathophysiological event in which the controlled dissolution and rupture followed by repair of otherwise healthy tissue occurs...
  62. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASM
    Robert MacDonald; Fiscal Year: 2000
    b>Rupture of an intracranial aneurysm, causing subarachnoid hemorrhage (SAH), afflicts about 30,000 North Americans per year...
  63. MECHANISMS OF FETAL MEMBRANE RUPTURE
    Jerome F Strauss; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Preterm premature rupture of the fetal membranes (PPROM) is a major cause of maternal morbidity and premature birth...
  64. MATERNAL SERUM INTERLEUKIN 6 IN PRETERM PREMATURE RUPTURE OF MEMBRANES
    Amy Murtha; Fiscal Year: 1999
    Purpose: Preterm premature rupture of membranes occurs in approximately 2% of all pregnancies and accounts for 20% of perinatal deaths...
  65. MATERNAL SERUM INTERLEUKIN 6 IN PRETERM PREMATURE RUPTURE OF MEMBRANES
    Amy Murtha; Fiscal Year: 2001
    Purpose: Preterm premature rupture of membranes occurs in approximately 2% of all pregnancies and accounts for 20% of perinatal deaths...
  66. MATERNAL SERUM INTERLEUKIN 6 IN PRETERM PREMATURE RUPTURE OF MEMBRANES
    Amy Murtha; Fiscal Year: 2000
    Purpose: Preterm premature rupture of membranes occurs in approximately 2% of all pregnancies and accounts for 20% of perinatal deaths...
  67. INCIDENCE AND RISK FACTORS FOR UTERINE RUPTURE
    George Macones; Fiscal Year: 1999
    ..Although this procedure is generally believed to be safe, there is a small risk of uterine rupture in these women...
  68. INCIDENCE AND RISK FACTORS FOR UTERINE RUPTURE
    George Macones; Fiscal Year: 2000
    ..Although this procedure is generally believed to be safe, there is a small risk of uterine rupture in these women...
  69. ELECTRON MICROSCOPY OF THE INNER EAR
    Robert Kimura; Fiscal Year: 1991
    ..An increase in endolymphatic pressure and membrane rupture are theorized to initiate clinical symptoms for Meniere's disease...
  70. Endovascular device and treatment for stabilizing aortic aneurysms
    MATTHEW FRANK OGLE; Fiscal Year: 2010
    ..AAAs) are associated with impaired arterial wall integrity, leading to abnormal ballooning and eventual fatal rupture. Currently the sole treatment for such aneurysms is surgical intervention...
  71. EVOLVING MECHANICS OF INTRALUMINAL THROMBUS: FROM FORMATION TO ORGANIZATION
    JAY HUMPHREY; Fiscal Year: 2009
    ..of the devastating complications of intraluminal thrombus is the acute occlusion of a coronary artery following rupture of a vulnerable plaque, which can cause sudden death...
  72. MECHANISMS OF FETAL MEMBRANE RUPTURE
    JEROME STRAUSS; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Preterm premature rupture of the fetal membranes (PPROM) is a major cause of maternal morbidity and premature birth...
  73. Mechanisms of Traumatic Rupture in Arteries
    KUROSH K DARVISH; Fiscal Year: 2010
    ..The research plan addresses the problem of traumatic aortic rupture (TAR) that is a leading cause of fatality in motor vehicle accidents...
  74. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt Barnhart; Fiscal Year: 2007
    ..If the diagnosis of EP is delayed potential rupture, resulting in greater risks of morbidity and mortality, can occur...
  75. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt T Barnhart; Fiscal Year: 2010
    ..If the diagnosis of EP is delayed potential rupture, resulting in greater risks of morbidity and mortality, can occur...
  76. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt Barnhart; Fiscal Year: 2009
    ..If the diagnosis of EP is delayed potential rupture, resulting in greater risks of morbidity and mortality, can occur...
  77. Mechanisms of Traumatic Rupture in Arteries
    Kurosh Darvish; Fiscal Year: 2009
    ..The research plan addresses the problem of traumatic aortic rupture (TAR) that is a leading cause of fatality in motor vehicle accidents...