sick building syndrome

Summary

Summary: A group of symptoms that are two- to three-fold more common in those who work in large, energy-efficient buildings, associated with an increased frequency of headaches, lethargy, and dry skin. Clinical manifestations include hypersensitivity pneumonitis (ALVEOLITIS, EXTRINSIC ALLERGIC); allergic rhinitis (RHINITIS, ALLERGIC, PERENNIAL); ASTHMA; infections, skin eruptions, and mucous membrane irritation syndromes. Current usage tends to be less restrictive with regard to the type of building and delineation of complaints. (From Segen, Dictionary of Modern Medicine, 1992)

Top Publications

  1. ncbi Health effects of indoor fungal bioaerosol exposure
    Frederick Fung
    Department of Occupational Medicine, Sharp Rees Stealy Medical Group, San Diego, California, USA
    Appl Occup Environ Hyg 18:535-44. 2003
  2. ncbi Indoor moisture and mold-related health problems
    Eckardt Johanning
    Fungal Research Group Foundation, Inc 4 Executive Drive, Albany, New York 12203, USA
    Eur Ann Allergy Clin Immunol 36:182-5. 2004
  3. ncbi Sick building syndrome (SBS) and exposure to water-damaged buildings: time series study, clinical trial and mechanisms
    Ritchie C Shoemaker
    Chronic Fatigue Center, 500 Market Street, Suite 103, Pocomoke City, MD 21851, USA
    Neurotoxicol Teratol 28:573-88. 2006
  4. pmc Building health: an epidemiological study of "sick building syndrome" in the Whitehall II study
    A F Marmot
    AMA, Linton House, London, UK
    Occup Environ Med 63:283-9. 2006
  5. ncbi Associations between indoor CO2 concentrations and sick building syndrome symptoms in U.S. office buildings: an analysis of the 1994-1996 BASE study data
    M G Apte
    Indoor Environment Department, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Indoor Air 10:246-57. 2000
  6. ncbi Sick building syndrome and perceived indoor environment in relation to energy saving by reduced ventilation flow during heating season: a 1 year intervention study in dwellings
    K Engvall
    Stockholm Office of Research and Statistics, Stockholm, Sweden
    Indoor Air 15:120-6. 2005
  7. ncbi Associations among sick building syndrome, psychosocial factors, and personality traits
    Roma Runeson
    Uppsala University Hospital, Sweden
    Percept Mot Skills 100:747-59. 2005
  8. ncbi Asthma symptoms in relation to building dampness and odour in older multifamily houses in Stockholm
    K Engvall
    Stockholm Office of Research and Statistics, Sweden
    Int J Tuberc Lung Dis 5:468-77. 2001
  9. doi Sick building syndrome in relation to air exchange rate, CO(2), room temperature and relative air humidity in university computer classrooms: an experimental study
    Dan Norback
    Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, University Hospital, Uppsala, Sweden
    Int Arch Occup Environ Health 82:21-30. 2008
  10. ncbi Studies of sick building syndrome. IV. Mycotoxicosis
    Yehudith Assoulin-Daya
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 95616, USA
    J Asthma 39:191-201. 2002

Detail Information

Publications168 found, 100 shown here

  1. ncbi Health effects of indoor fungal bioaerosol exposure
    Frederick Fung
    Department of Occupational Medicine, Sharp Rees Stealy Medical Group, San Diego, California, USA
    Appl Occup Environ Hyg 18:535-44. 2003
    ..Additional studies are needed to document human exposure-disease and dose-response relationships...
  2. ncbi Indoor moisture and mold-related health problems
    Eckardt Johanning
    Fungal Research Group Foundation, Inc 4 Executive Drive, Albany, New York 12203, USA
    Eur Ann Allergy Clin Immunol 36:182-5. 2004
    ..Proper recognition of microbial related health problems and the differential diagnosis of sick building syndrome (SBS) or building related illness (BRI) are important for early and effective exposure intervention, ..
  3. ncbi Sick building syndrome (SBS) and exposure to water-damaged buildings: time series study, clinical trial and mechanisms
    Ritchie C Shoemaker
    Chronic Fatigue Center, 500 Market Street, Suite 103, Pocomoke City, MD 21851, USA
    Neurotoxicol Teratol 28:573-88. 2006
    ..amplification often describe a syndrome involving multiple organ systems, commonly referred to as "sick building syndrome" (SBS), following chronic exposure to the indoor air...
  4. pmc Building health: an epidemiological study of "sick building syndrome" in the Whitehall II study
    A F Marmot
    AMA, Linton House, London, UK
    Occup Environ Med 63:283-9. 2006
    b>Sick building syndrome (SBS) is described as a group of symptoms attributed to the physical environment of specific buildings. Isolating particular environmental features responsible for the symptoms has proved difficult...
  5. ncbi Associations between indoor CO2 concentrations and sick building syndrome symptoms in U.S. office buildings: an analysis of the 1994-1996 BASE study data
    M G Apte
    Indoor Environment Department, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Indoor Air 10:246-57. 2000
    ..indoor concentrations of air pollutants due, in part, to lower ventilation rates are a potential cause of sick building syndrome (SBS) symptoms in office workers...
  6. ncbi Sick building syndrome and perceived indoor environment in relation to energy saving by reduced ventilation flow during heating season: a 1 year intervention study in dwellings
    K Engvall
    Stockholm Office of Research and Statistics, Stockholm, Sweden
    Indoor Air 15:120-6. 2005
    ..The aim was to study if a 25-30% reduction of outdoor ventilation flow during heating season influenced sick building syndrome (SBS) and the perception of the indoor environment...
  7. ncbi Associations among sick building syndrome, psychosocial factors, and personality traits
    Roma Runeson
    Uppsala University Hospital, Sweden
    Percept Mot Skills 100:747-59. 2005
    ..In conclusion, personality aspects seem to play an important role for reporting medical symptoms, work satisfaction, work stress, and climate of cooperation at work, but different personality aspects could be important in men and women...
  8. ncbi Asthma symptoms in relation to building dampness and odour in older multifamily houses in Stockholm
    K Engvall
    Stockholm Office of Research and Statistics, Sweden
    Int J Tuberc Lung Dis 5:468-77. 2001
    ..Exposure to odorous compounds from building dampness may be significant with respect to respiratory symptoms and possibly atopic sensitisation...
  9. doi Sick building syndrome in relation to air exchange rate, CO(2), room temperature and relative air humidity in university computer classrooms: an experimental study
    Dan Norback
    Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, University Hospital, Uppsala, Sweden
    Int Arch Occup Environ Health 82:21-30. 2008
    ..To study the effects of ventilation and temperature changes in computer classrooms on symptoms in students...
  10. ncbi Studies of sick building syndrome. IV. Mycotoxicosis
    Yehudith Assoulin-Daya
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 95616, USA
    J Asthma 39:191-201. 2002
    ..In this review we discuss selected aspects of the microbiology of mycotoxin-producing molds and their potential role in human immunopathology with respect to wet building environments...
  11. doi Dampness and moulds in workplace buildings: associations with incidence and remission of sick building syndrome (SBS) and biomarkers of inflammation in a 10 year follow-up study
    Xin Zhang
    Research Center for Environmental Science and Engineering, Shanxi University, 030006, Taiyuan, China
    Sci Total Environ 430:75-81. 2012
    ..and indoor moulds in workplace buildings and selected biomarkers as well as incidence and remission of sick building syndrome (SBS)...
  12. ncbi Symptom definitions for SBS (sick building syndrome) in residential dwellings
    Bing Ling Wang
    Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Int J Hyg Environ Health 211:114-20. 2008
    The potential risk factors for sick building syndrome (SBS) in newly built dwellings were investigated...
  13. ncbi Environmental tobacco smoke exposure and overtime work as risk factors for sick building syndrome in Japan
    T Mizoue
    Department of Clinical Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan
    Am J Epidemiol 154:803-8. 2001
    b>Sick building syndrome (SBS) is an increasingly common health problem for workers in modern office buildings. It is characterized by irritation of mucous membranes and the skin and general malaise...
  14. ncbi The effects of outdoor air supply rate in an office on perceived air quality, sick building syndrome (SBS) symptoms and productivity
    P Wargocki
    International Centre for Indoor Environment and Energy, Technical University of Denmark, Kongens Lyngby, Denmark
    Indoor Air 10:222-36. 2000
    Perceived air quality, Sick Building Syndrome (SBS) symptoms and productivity were studied in a normally furnished office space (108 m3) ventilated with an outdoor airflow of 3, 10 or 30 L/s per person, corresponding to an air change rate ..
  15. ncbi Possible role of fungal hemolysins in sick building syndrome
    Stephen J Vesper
    U S Environmental Protection Agency Office of Research and Development, National Exposure Research Laboratory 26 W M L King Drive Cincinnati, Ohio 45268, USA
    Adv Appl Microbiol 55:191-213. 2004
  16. ncbi Relationship between indoor chemical concentrations and subjective symptoms associated with sick building syndrome in newly built houses in Japan
    Tomoko Takigawa
    Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata cho, Kita ku, Japan
    Int Arch Occup Environ Health 83:225-35. 2010
    This study explored possible associations between chemical substances and sick building syndrome (SBS)-type symptoms of residents living in new houses in Japan.
  17. ncbi Indoor environment in dwellings, asthma, allergies, and sick building syndrome in the Swedish population: a longitudinal cohort study from 1989 to 1997
    B Sahlberg
    Department of Occupational and Environmental Medicine, Uppsala University Hospital and Uppsala University, Uppsala, Sweden
    Int Arch Occup Environ Health 82:1211-8. 2009
    To investigate changes of sick building syndrome (SBS) and different types of indoor exposures at home over an 8-year follow-up period (1989-1997), and onset of SBS symptoms in relation to size of residence town and education level.
  18. ncbi Symptoms in relation to chemicals and dampness in newly built dwellings
    Y Saijo
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8638, Japan
    Int Arch Occup Environ Health 77:461-70. 2004
    ..The aim of this study was to clarify whether symptoms in residents living in newly built dwellings were related to chemicals and dampness...
  19. ncbi Why do women suffer from sick building syndrome more often than men?--subjective higher sensitivity versus objective causes
    S Brasche
    Friedrich Schiller University Jena, Institute of Occupational, Social and Environmental Medicine, Department of Indoor Climatology Erfurt, Gustav Freytag Str 1, D 99096 Erfurt, Germany
    Indoor Air 11:217-22. 2001
    Office workers often report so-called sick building syndrome (SBS) symptoms affecting the skin, mucous membranes and nervous system...
  20. ncbi Perceived air quality, sick building syndrome (SBS) symptoms and productivity in an office with two different pollution loads
    P Wargocki
    International Centre for Indoor Environment and Energy, Technical University of Denmark, Lyngby, Denmark
    Indoor Air 9:165-79. 1999
    Perceived air quality, Sick Building Syndrome (SBS) symptoms and productivity were studied in an existing office in which the air pollution level could be modified by introducing or removing a pollution source...
  21. ncbi A case of sick building syndrome in a Japanese office worker
    Hiroko Nakazawa
    Department of Otorhinolaryngology, Kansai Medical University, Fumizono cho, Moriguchi, Osaka 570 8506, Japan
    Ind Health 43:341-5. 2005
    The adverse health effects caused by indoor air pollution are termed "sick building syndrome". We report such a patient whose symptoms appeared in the workplace...
  22. doi Relationship between sick building syndrome and indoor environmental factors in newly built Japanese dwellings
    Makoto Takeda
    Department of Public Health Science, Graduated School of Medicine, Hokkaido University, N15, W7, Kita ku, Sapporo, 060 8638, Japan
    Int Arch Occup Environ Health 82:583-93. 2009
    ..The aim of this study is to clarify which factors are related to sick building syndrome (SBS) in newly built dwellings at Hokkaido, Japan, through a comprehensive evaluation of the indoor ..
  23. ncbi The roles of Penicillium and Aspergillus in sick building syndrome
    Christopher J Schwab
    Department of Microbiology and Immunology Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Adv Appl Microbiol 55:215-38. 2004
  24. ncbi Dampness in buildings as a risk factor for health effects, EUROEXPO: a multidisciplinary review of the literature (1998-2000) on dampness and mite exposure in buildings and health effects
    C G Bornehag
    Swedish National Testing and Research Institute, Boras, Sweden
    Indoor Air 14:243-57. 2004
    ..A general conclusion from the work was that there is a strong need for multidisciplinary reviews in scientific journals of articles dealing with associations between indoor environmental factors and health effects...
  25. ncbi Studies on the role of fungi in Sick Building Syndrome
    David C Straus
    Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    Arch Environ Health 58:475-8. 2003
    b>Sick Building Syndrome is a term used to describe symptoms in humans which result from problems with indoor air quality. Common complaints include dyspnea, flu-like symptoms, watering eyes, and allergic rhinitis...
  26. doi An update on sick building syndrome
    Dan Norback
    Department of Medical Science, Occupational and Environmental Medicine, University Hospital, Uppsala University, Uppsala, Sweden
    Curr Opin Allergy Clin Immunol 9:55-9. 2009
    The aim is to describe recent insight into risk factors for symptoms included in the sick building syndrome (SBS) and to give an insight into preventive work to reduce SBS.
  27. doi Sick Building Syndrome: is mould the cause?
    Abba I Terr
    UCSF Medical Center, San Francisco, California 94108, USA
    Med Mycol 47:S217-22. 2009
    ..Non-specific irritation from moulds via the inhalation route is also a controversial subject that remains unproven. Published studies alleging an epidemiologic causal relationship are unconvincing...
  28. doi Respiratory inflammatory responses among occupants of a water-damaged office building
    M Akpinar-Elci
    CDC NIOSH Division of Respiratory Diseases Studies, Morgantown, WV, USA
    Indoor Air 18:125-30. 2008
    ..Of the analyses assessed, EBC IL-8 showed the most significant relationship with a number of symptoms and physician-diagnosed asthma...
  29. ncbi Molds, mycotoxins, and sick building syndrome
    David C Straus
    Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
    Toxicol Ind Health 25:617-35. 2009
    ..work we have done since 2004 regarding the importance of molds and their mycotoxins in the phenomenon of sick building syndrome (SBS)...
  30. ncbi Effect of formaldehyde on the expression of adhesion molecules in nasal microvascular endothelial cells: the role of formaldehyde in the pathogenesis of sick building syndrome
    W J Kim
    Department of Otorhinolaryngology, Chiba University School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba City, Chiba 260 0856, Japan
    Clin Exp Allergy 32:287-95. 2002
    Formaldehyde is associated with sick building syndrome (SBS), a set of diffuse and irritative symptoms predominantly involving the eyes and the respiratory tract. However, its pathophysiological mechanism in SBS has not yet been clarified.
  31. pmc Sick building syndrome
    P S Burge
    Occupational Lung Disease Unit, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK
    Occup Environ Med 61:185-90. 2004
  32. ncbi Possible sources of sick building syndrome in a Tennessee middle school
    C M Scheel
    Department of Biology, Middle Tennessee State University, Murfreesboro 37132, USA
    Arch Environ Health 56:413-7. 2001
    b>Sick Building Syndrome has been reported with increasing frequency during recent years. Buildings that have sustained water damage harbor various molds, some of which may be toxic...
  33. ncbi A time-series study of sick building syndrome: chronic, biotoxin-associated illness from exposure to water-damaged buildings
    Ritchie C Shoemaker
    Chronic Fatigue Center, 500 Market Street, Suite 103, Pocomoke City, MD 21851, United States
    Neurotoxicol Teratol 27:29-46. 2005
    ..Such data will improve the assessment of human health risk from chronic exposure to WDBs...
  34. pmc Office work exposures [corrected] and respiratory and sick building syndrome symptoms
    Maritta S Jaakkola
    Institute of Occupational and Environmental Medicine, University of Birmingham, Edgbaston, Birmingham, B15 2TT UK
    Occup Environ Med 64:178-84. 2007
    ..between exposure to carbonless copy paper (CCP), paper dust, and fumes from photocopiers and printers (FPP), and the occurrence of sick building syndrome (SBS)-related symptoms, chronic respiratory symptoms and respiratory infections.
  35. ncbi Visual display terminal work and sick building syndrome--the role of psychosocial distress in the relationship
    Tatsuhiko Kubo
    Department of Clinical Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan
    J Occup Health 48:107-12. 2006
    The present study investigated the association between visual display terminal (VDT) work and sick building syndrome (SBS) and the role of psychosocial factors in the relationship...
  36. ncbi Were volatile organic compounds the inducing factors for subjective symptoms of employees working in newly constructed hospitals?
    Tomoko Takigawa
    Department of Public Health, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Environ Toxicol 19:280-90. 2004
    ..applied to select variables significantly associated with the subjective symptoms that can be induced by sick building syndrome. The results showed that subjective symptoms of deterioration in the skin, eye, ear, throat, chest, ..
  37. ncbi Bioaerosols and sick building syndrome: particles, inflammation, and allergy
    Robert J Laumbach
    Environmental and Occupational Health Sciences Institute, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Curr Opin Allergy Clin Immunol 5:135-9. 2005
    b>Sick building syndrome is a poorly understood condition that can be vexing to clinicians and public health investigators alike. Concerns about possible causes have recently shifted to bioaerosols, especially indoor mold contamination...
  38. ncbi Pet keeping and dampness in the dwelling: associations with airway infections, symptoms, and physiological signs from the ocular and nasal mucosa
    J V Bakke
    Section for Occupational Medicine, Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien, Bergen, Norway
    Indoor Air 17:60-9. 2007
    ..Dampness in the dwelling may have inflammatory effects on the airway mucosa, possibly mediated via increased infection proneness...
  39. ncbi Microbial cell wall agents and sick building syndrome
    Ragnar Rylander
    Department of Environmental Medicine University of Gothenburg Gothenburg, Sweden
    Adv Appl Microbiol 55:139-54. 2004
  40. ncbi Sick building syndrome in relation to building dampness in multi-family residential buildings in Stockholm
    K Engvall
    Department of Medical Science/Occupational and Environmental Medicine, University Hospital, Uppsala University, Sweden
    Int Arch Occup Environ Health 74:270-8. 2001
    OBJECTIVES: The aim was to study relationships between symptoms compatible with sick building syndrome (SBS) on one hand, and different indicators of building dampness in Swedish multi-family buildings on the other...
  41. doi A longitudinal study of environmental risk factors for subjective symptoms associated with sick building syndrome in new dwellings
    Tomoko Takigawa
    Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700 8558 Okayama, Japan
    Sci Total Environ 407:5223-8. 2009
    ..environmental risk factors, including indoor chemicals, mold, and dust mite allergens, which could cause sick building syndrome (SBS)-type symptoms in new houses...
  42. ncbi Fungal contamination as a major contributor to sick building syndrome
    De wei Li
    P and K Microbiology Services, Inc, 1936 Olney Ave Cherry Hill, New Jersey 08003, USA
    Adv Appl Microbiol 55:31-112. 2004
  43. ncbi On the history of indoor air quality and health
    J Sundell
    International Center for Indoor Environment and Energy, Technical University of Denmark, Lyngby, Denmark
    Indoor Air 14:51-8. 2004
    ..Cancer of the lungs is related to indoor radon and ETS exposure. Allergies, airway infections and sick building syndrome are associated with, e.g., "dampness", a low ventilation rate, and plasticizers...
  44. ncbi [11th WaBoLu interior meeting, May 17-19, 2004. Summary of the most important results]
    H J Moriske
    FG Gesundheitsbezogene Exposition, Innenraumhygiene, Umweltbundesamt, Berlin
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:1009-13. 2004
  45. ncbi Dampness in buildings and health (DBH): Report from an ongoing epidemiological investigation on the association between indoor environmental factors and health effects among children in Sweden
    C G Bornehag
    Swedish National Testing and Research Institute, Sweden
    Indoor Air 14:59-66. 2004
    ..Finally, in a fourth phase, controlled experimental studies in climate chambers and in vitro tests regarding findings from DBH-Phase 2 are planned to be conducted during 2004-08...
  46. ncbi Impact of indoor air temperature and humidity in an office on perceived air quality, SBS symptoms and performance
    L Fang
    International Centre for Indoor Environment and Energy, Technical University of Denmark
    Indoor Air 14:74-81. 2004
    Perceived air quality (PAQ), sick building syndrome (SBS) symptoms and performance of office work were studied in a real office space at three levels of air temperature and humidity and two levels of ventilation rate (20 degrees C/40%, 23 ..
  47. ncbi Fungi and the indoor environment: their impact on human health
    J D Cooley
    Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    Adv Appl Microbiol 55:1-30. 2004
  48. ncbi Moisture-problem buildings with molds causing work-related diseases
    Kari Reijula
    Finnish Institute of Occupational Health Arinatie 3A, FIN 00370 Helsinki, Finland
    Adv Appl Microbiol 55:175-89. 2004
  49. ncbi Fungicidal properties of Pinus sylvestris L. for improvement of air quality
    Ona Motiejūnaite
    Vilnius Pedagogical University, Studentu 39, 08106 Vilnius, Lithuania
    Medicina (Kaunas) 40:787-94. 2004
    b>Sick building syndrome is a term commonly used to describe the consequences of poor indoor air quality...
  50. ncbi Controversies regarding dampness and mold growth in homes
    Jay M Portnoy
    Children s Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA
    Allergy Asthma Proc 28:257-8. 2007
  51. ncbi Airborne mycotoxins discovered in moldy buildings
    Paul D Thacker
    Environ Sci Technol 38:282A. 2004
  52. ncbi Proactive approaches for mold-free interior environments
    Katherine Warsco
    Department of Interior Design and Merchandising, College of Human Ecology, East Carolina University, Greenville, North Carolina 28858 4353, USA
    Arch Environ Health 58:512-22. 2003
    ..The authors present trade-offs between best practices for designing mold-free indoor environments (including considerations of cost, maintenance, and operation) and occupant comfort, health, and well-being...
  53. ncbi Risk factors in heating, ventilating, and air-conditioning systems for occupant symptoms in US office buildings: the US EPA BASE study
    M J Mendell
    Lawrence Berkeley National Laboratory, Indoor Environment Department, CA, USA
    Indoor Air 18:301-16. 2008
    ..6. Symptoms may be due to microbial exposures from poorly maintained ventilation systems and to greater levels of vehicular pollutants at air intakes nearer the ground level. Replication and explanation of these findings is needed...
  54. doi Outdoor ozone and building-related symptoms in the BASE study
    M G Apte
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Indoor Air 18:156-70. 2008
    ..If the observed associations are confirmed as causal, ventilation system ozone removal technologies could reduce UR BRS prevalence when higher ambient ozone levels are present...
  55. ncbi Excess dampness and mold growth in homes: an evidence-based review of the aeroirritant effect and its potential causes
    Andrew P Hope
    Division of Allergy, Asthma and Immunology, Scripps Clinic, La Jolla, California 92037, USA
    Allergy Asthma Proc 28:262-70. 2007
    ..These studies support the role of VOCs in contributing to the aeroirritant symptoms of occupants of damp and mold-contaminated homes...
  56. ncbi Passenger evaluation of the optimum balance between fresh air supply and humidity from 7-h exposures in a simulated aircraft cabin
    P Strøm-Tejsen
    International Centre for Indoor Environment and Energy, Department of Mechanical Engineering, Technical University of Denmark, Lyngby, Denmark
    Indoor Air 17:92-108. 2007
    ..On the contrary, it intensified complaints of headache, dizziness, and claustrophobia, due to the increased level of contaminants...
  57. ncbi Indoor air pollution by 2-ethyl-1-hexanol in non-domestic buildings in Nagoya, Japan
    Kiyoshi Sakai
    Department of Environmental Health, Nagoya City Public Health Research Institute, 1 11 Hagiyama cho, Mizuho ku, Nagoya 467 8615, Japan
    J Environ Monit 8:1122-8. 2006
    ..Mechanical ventilation was effective in the temporary reduction of indoor 2-ethyl-1-hexanol level. These results suggest that the predominant source of 2-ethyl-1-hexanol was indoor areas...
  58. ncbi Preventing and responding to mold contamination
    Steve Silicato
    MARCOR Remediation, Inc, Hunt Valley, MD, USA
    Occup Health Saf 75:128, 132-3. 2006
  59. ncbi Airborne fungal spores in a cross-sectional study of office buildings
    David L MacIntosh
    Environmental Health and Engineering, Inc, Newton, Massachusetts 02459, USA
    J Occup Environ Hyg 3:379-89. 2006
    ..The BASE study provides normative data on concentrations of fungal spores that can aid in identification of problematic levels of mold in buildings...
  60. ncbi [Sick building syndrome due to exposure to pentachlorophenol in the office: a case report]
    Tomasz Wittczak
    Kliniki Chorób Zawodowych
    Med Pr 57:21-4. 2006
    b>Sick building syndrome" (SBS) is a group of symptoms experienced by people working in various buildings...
  61. ncbi A nationwide study of indoor and outdoor environments in allergen avoidance and conventional daycare centers in Sweden
    K Broms
    Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology, Uppsala University, Uppsala, Sweden
    Indoor Air 16:227-35. 2006
    ..0; P = 0.001), and washing of pillows/mattresses (OR = 2.74; P = 0.005) and curtains (OR = 9.07; P = 0.001). In conclusion, allergy avoidance daycare centers differ from other daycare centers, and may have better indoor environments...
  62. ncbi [Microbiological quality of indoor air at the School of Building and Environmental Engineering at Białystok University of Technology]
    Andrzej Butarewicz
    Katedra Biologii Sanitarnej i Biotechnologii, Politechnika Białostocka, 15 351 Białystok, ul Wiejska 45E
    Rocz Panstw Zakl Hig 56:199-206. 2005
    ..Because of the students' and other workers' safety, monitoring of microbiological pollution of the indoor air must be done and existing emergency to improve the quality of the air must be lead...
  63. ncbi [Chemical sensitivity (CS)]
    Satoshi Ishikawa
    Clinical Environmental Health Center, Kitasato Hospital, The Kitasato Institute
    Nihon Rinsho 63:179-84. 2005
  64. ncbi Double blind placebo controlled exposure to molds: exposure system and clinical results
    H W Meyer
    Epidemiological Research Unit, Clinic of Occupational and Environmental Medicine, H S Copenhagen University Hospital Bispebjerg, Copenhagen NV, Denmark
    Indoor Air 15:73-80. 2005
    ..However, a statistical type II error cannot be excluded because of the small sample size...
  65. ncbi Effects of moisture-damage repairs on microbial exposure and symptoms in schoolchildren
    T Meklin
    Department of Environmental Health, National Public Health Institute, Kuopio, Finland
    Indoor Air 15:40-7. 2005
    ..The change in the prevalence of symptoms in the reference schools was minor. The results suggest that increased symptom prevalence among schoolchildren in moisture-damaged schools can be managed with proper repair of the moisture damage...
  66. ncbi Molds in floor dust, building-related symptoms, and lung function among male and female schoolteachers
    N E Ebbehøj
    Epidemiological Research Unit, Clinic of Occupational and Environmental Medicine, H S Copenhagen University Hospital, Bispebjerg, Copenhagen NV, Denmark
    Indoor Air 15:7-16. 2005
    ..None of the lung function tests performed in this study were associated with mold exposure, to the 'water damaged' vs. 'non-damaged' classification, or to the symptoms reported. IL-8 and ECP were not associated either...
  67. ncbi Concentrations of airborne culturable bacteria in 100 large US office buildings from the BASE study
    F C Tsai
    Environmental Health Laboratory Branch, California Department of Health Services, Richmond, CA 94804 6403, USA
    Indoor Air 15:71-81. 2005
    ..g. the 90th percentile, 175 CFU/m3) of these 100 representative buildings may serve as upper bounds to develop interpretation guidelines for office environments and similar non-manufacturing workplaces in various climate zones...
  68. ncbi Do you have sick building syndrome?
    Gwendolyn Edwards
    Women s Services, Bayhealth Medical Center, Dover, DE, USA
    Nursing 38:58-9. 2008
  69. ncbi Summary of the 5th International Conference on Bioaerosols, Fungi, Bacteria, Mycotoxins, and Human Health
    Kaye H Kilburn
    Arch Environ Health 58:538-42. 2003
    ..org/index.html>. For details on the research summarized herein, please contact the presenting authors via their e-mail addresses. This reference system should aid in the dissemination of information that is current but not yet published...
  70. ncbi Building characteristics, indoor air quality and recurrent wheezing in very young children (BAMSE)
    G Emenius
    Department of Environmental Health, Stockholm County Council, Norrbacka, 3rd Floor, SE 171 76 Stockholm, Sweden
    Indoor Air 14:34-42. 2004
    ..Thus, improvements of the building quality may have potential to prevent infant wheezing...
  71. ncbi Nasal lavage biomarkers: effects of water damage and microbial growth in an office building
    R Wålinder
    Department of Medical Sciences Occupational and Environmental Medicine Uppsala University, University Hospital, Sweden
    Arch Environ Health 56:30-6. 2001
    ..The results also support conclusions of earlier studies, indicating that building dampness is related to respiratory inflammation...
  72. ncbi Symptoms prevalence among office employees and associations to building characteristics
    K Skyberg
    National Institute of Occupational Health, Oslo, Norway
    Indoor Air 13:246-52. 2003
    ..5 (95%CI 1.1-2.0). A high ventilation flow or central ventilation unit filter EU7 vs. EU8 seemed to be associated with an increased risk of general symptoms. Absence of local temperature control increased the risk of mucosal symptoms...
  73. ncbi Ocular, nasal, dermal and respiratory symptoms in relation to heating, ventilation, energy conservation, and reconstruction of older multi-family houses
    K Engvall
    Stockholm Office of Research and Statistics, Stockholm, Sweden
    Indoor Air 13:206-11. 2003
    The aim was to study relationships between symptoms compatible with the sick building syndrome, type of heating and ventilation system, energy saving, and reconstruction in older dwellings...
  74. ncbi Moulds, moisture and microbial contamination of First Nations housing in British Columbia, Canada
    R Lawrence
    Health Canada, First Nations and Inuit Health Branch, 540-757 West Hastings, Vancouver, British Columbia, V6C 3E6, Canada
    Int J Circumpolar Health 60:150-6. 2001
    ..Our experience suggests that substandard housing is a major contributor to poor health in First Nations communities...
  75. ncbi Air quality and well-being perception in subjects attending university libraries in Modena (Italy)
    E Righi
    Department of Hygiene, Microbiology and Biostatistics, University of Modena and Reggio Emilia, Italy
    Sci Total Environ 286:41-50. 2002
    ..This investigation was suggested by an increase in reported symptoms related to Sick Building Syndrome (SBS) observed in recent decades among people spending most of their time in various indoor environments, ..
  76. ncbi Indoor biological contaminants and symptoms of sick building syndrome in office buildings in Mauritius
    R Bholah
    Department of Health and Medical Sciences, Faculty of Science, University of Mauritius, Reduit, Mauritius
    Int J Environ Health Res 12:93-8. 2002
    This study was carried out to investigate possible relationship between bio-contaminants and symptoms of sick building syndrome among office workers in Mauritius...
  77. ncbi Association of ventilation system type with SBS symptoms in office workers
    O Seppanen
    Laboratory of Heating, Ventilating and Air Conditioning, Helsinki University of Technology, Helsinki, Finland
    Indoor Air 12:98-112. 2002
    ..synthesis of current knowledge about the associations of ventilation system types in office buildings with sick building syndrome (SBS) symptoms and discusses potential explanations for the associations...
  78. ncbi Ventilation and health in non-industrial indoor environments: report from a European multidisciplinary scientific consensus meeting (EUROVEN)
    P Wargocki
    Technical University of Denmark, Kongens Lyngby, Denmark
    Indoor Air 12:113-28. 2002
    ..the group agreed that ventilation is strongly associated with comfort (perceived air quality) and health [Sick Building Syndrome (SBS) symptoms, inflammation, infections, asthma, allergy, short-term sick leave], and that an association ..
  79. ncbi Indoor particles and symptoms among office workers: results from a double-blind cross-over study
    Mark J Mendell
    National Institute for Occupational Safety and Health, Cincinnati, OH, USA
    Epidemiology 13:296-304. 2002
    ..We studied the effects of removing small airborne particles in an office building without unusual contaminant sources or occupant complaints...
  80. ncbi Microbial contamination of indoor air due to leakages from crawl space: a field study
    M Airaksinen
    Laboratory of Heating, Ventilating and Air Conditioning, Helsinki University of Technology, HUT, Helsinki, Finland
    Indoor Air 14:55-64. 2004
    ..We conclude that a building with a crawl space and pressure difference over the base floor could be a potential risk for indoor air quality in the first floor apartments...
  81. pmc Populations and determinants of airborne fungi in large office buildings
    H Jasmine Chao
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 110:777-82. 2002
    ..More studies are needed to correlate airborne fungi and occupants' health, controlling for seasonal effects and other important environmental factors...
  82. ncbi Creating mold-free buildings: a key to avoiding health effects of indoor molds
    Bruce M Small
    Foundation for Independent Research on Technology, and Health, Georgetown, Ontario, Canada
    Arch Environ Health 58:523-7. 2003
    ....
  83. ncbi The way we build now
    Geoffrey H Hutton
    Hutton Rostron, Guildford, Surrey, United Kingdom
    Arch Environ Health 58:505-11. 2003
    ..Relevant factors should be explored, and their effects understood, so that solutions in building can be developed before the use of fossil fuels must be abandoned altogether...
  84. ncbi Variability of personal chemical exposure in eight office buildings in Sweden
    Bo Glas
    Dermatology and Venereology, Department of Public Health and Clinical Medicine, Umea University, Sweden
    J Expo Anal Environ Epidemiol 14:S49-57. 2004
    ..These results also support the conclusion that in case-referent studies of "sick building syndrome" (SBS), referents to SBS cases can be randomised for building location.
  85. pmc HVAC officemate
    John Manuel
    Environ Health Perspect 112:A346. 2004
  86. ncbi Health symptoms caused by molds in a courthouse
    Tang G Lee
    Faculty of Environmental Design, The University of Calgary, Calgary, Alberta, Canada
    Arch Environ Health 58:442-6. 2003
    ....
  87. ncbi [General environmental pollutants and passive smoking]
    R Meister
    Marienkrankenhaus, , Asthma und Allergie, Bad Lippspringe
    Pneumologie 44:378-86. 1990
    ..Airtight sealing of buildings associated with reduced indoor ventilation results in novel health upsets ("sick building syndrome")...
  88. ncbi Chronic fatigue syndrome following a toxic exposure
    D Racciatti
    Department of Infectious Diseases, G D Annunzio University, Chieti Scalo, Italy
    Sci Total Environ 270:27-31. 2001
    ..implicates the exposure to chemical and/or food toxins as precipitating factors: ciguatera poisoning, sick building syndrome, Gulf War syndrome, exposure to organochlorine pesticides, etc...
  89. ncbi Health hazards and electromagnetic fields
    T Saunders
    Complement Ther Nurs Midwifery 9:191-7. 2003
    ..stress can affect animals and plant life as well as human beings and significantly contributes to sick building syndrome (SBS)...
  90. pmc Neurogenic inflammation and sensitivity to environmental chemicals
    W J Meggs
    Department of Emergency Medicine, East Carolina University School of Medicine, Greenville, NC 27858
    Environ Health Perspect 101:234-8. 1993
    ..The sick building syndrome and multiple chemical sensitivity syndrome have been defined as clinical entities in which exposure to ..
  91. ncbi Molecular identification of environmental bacteria in indoor air in the domestic home: description of a new species of Exiguobacterium
    Ivan Yuan
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
    Int J Environ Health Res 17:75-82. 2007
    ..microorganisms is important due to its potential aetiological role in development of conditions such as Sick Building Syndrome. Hence, laboratory identification of bacteriological components in any bioaerosol from buildings may help ..
  92. ncbi The dichotomy of relative humidity on indoor air quality
    Peder Wolkoff
    Indoor Environment Group, National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Environ Int 33:850-7. 2007
    ..mucous membranes, offices, ozone, pungency, sensory irritation, particles, precorneal tear film, sick building syndrome, stuffy air, and VOCs...
  93. ncbi Gene expression profiling in lung tissues from rats exposed to formaldehyde
    Donggeun Sul
    Graduate School of Medicine, Korea University, Anamdong 5 Ka, Sungbukku, Seoul, 136 701, South Korea
    Arch Toxicol 81:589-97. 2007
    ..as a carcinogen by the International Agency for Research on Cancer and one of the major factors causing sick building syndrome. In this study, we have investigated the effects of formaldehyde on mRNA expression in rat lung tissues by ..
  94. ncbi Cough: occupational and environmental considerations: ACCP evidence-based clinical practice guidelines
    Susan M Tarlo
    Toronto Western Hospital, EW7 449, 399 Bathurst St, Toronto, ON, M5T 2S8 Canada
    Chest 129:186S-196S. 2006
    ..It also aims to indicate when such causes should be considered in a clinical setting, and a general approach to assessment and management...
  95. ncbi [Syndromes in environmental medicine: variants of somatoform disorders]
    G A Wiesmüller
    Institut fur Hygiene und Umweltmedizin, Universitätsklinikums, RWTH Aachen
    Fortschr Neurol Psychiatr 69:175-88. 2001
    ..medicine, like Multiple Chemical Sensitivities (MCS), Idiopathic Environmental Intolerances (IEI), Sick Building Syndrome (SBS), Chronic Fatigue Syndrome (CFS), Candida Syndrome (CS), and Burnout Syndrome (BS), scientific ..
  96. ncbi Intercomparison of instruments used for safety and performance measurements of ultraviolet germicidal irradiation lamps
    Nicholas G Reed
    Laser Optical Radiation Program, US Army Center for Health Promotion and Preventive Medicine, Aberdeen Proving Ground, Maryland 21010, USA
    J Occup Environ Hyg 6:289-97. 2009
    Public health concerns such as multidrug-resistant tuberculosis, bioterrorism, pandemic influenza, and sick building syndrome have brought about increased interest in the use of ultraviolet germicidal irradiation (UVGI) to prevent the ..
  97. ncbi [Subjective evaluation of the work environment quality in offices]
    Elzbieta Jankowska
    Zakładu Zagrozeń Chemicznych i Pyłowych, Centralnego Instytutu Ochrony Pracy Państwowego Instytutu Badawczego w Warszawie
    Med Pr 54:437-44. 2003
    Exposure to harmful and strenuous factors in offices lead to the sick building syndrome (SBS) with its various symptoms: fatigue, dyspnoea, decreased ability to concentrate, irritation of mucous membranes of eyes as well as of the upper ..
  98. ncbi Evidence of inadequate ventilation in portable classrooms: results of a pilot study in Los Angeles County
    D G Shendell
    Environmental Sciences and Engineering Program, UCLA School of Public Health, Los Angeles, CA, USA
    Indoor Air 14:154-8. 2004
    ..Future school studies should include integrated and continuous measurements of T, RH, and ventilation with appropriate tracer gas methods, and other airflow measures...
  99. ncbi Identification of formaldehyde-responsive genes by suppression subtractive hybridization
    Min Ho Lee
    College of Pharmacy, Seoul National University, Seoul 151 742, South Korea
    Toxicology 243:224-35. 2008
    ..Therefore, formaldehyde has been considered as the most prevalent cause of sick building syndrome, which has become a major social problem, especially in developing urban areas...
  100. ncbi Electromagnetic hypersensitivity: biological effects of dirty electricity with emphasis on diabetes and multiple sclerosis
    Magda Havas
    Environmental and Resource Studies, Trent University, Peterborough, Ontario, Canada
    Electromagn Biol Med 25:259-68. 2006
    ..Graham/Stetzer (GS) filters have been installed in schools with sick building syndrome and both staff and students reported improved health and more energy...
  101. doi Relationship between selected indoor volatile organic compounds, so-called microbial VOC, and the prevalence of mucous membrane symptoms in single family homes
    Atsuko Araki
    Hokkaido University Graduate School of Medicine, Department of Public Health Sciences, Kita 15, Nishi 7, Kita ku, Sapporo, Hokkaido 060 8638, Japan
    Sci Total Environ 408:2208-15. 2010
    ..indoor MVOC levels in single family homes and to evaluate the relationship between exposure to them and sick building syndrome (SBS)...

Research Grants32

  1. Destruction of Air-Borne Pathogenic Bacteria
    JAMES KITTRELL; Fiscal Year: 2002
    ..abstract_text> ..
  2. Indoor Environment and Symptoms in Office Building
    MARK MENDELL; Fiscal Year: 2006
    ..abstract_text> ..
  3. Role of TRP Channels in Environmental Irritant-Induced Headache
    GERRY S contact OXFORD; Fiscal Year: 2010
    ..responsible for the increased incidence of migraine as well as more recently described disorders such as Sick building syndrome (SBS) and Multiple chemical sensitivity (MCS)...
  4. ULTRAVIOLET LIGHTS IN HVAC SYSTEMS--EFFECT ON HEALTH AND
    Dick Menzies; Fiscal Year: 2000
    Non specific building related illnesses or "sick building syndrome" are disorders of unknown cause that are estimated to affect 20-30 percent of workers in over one million buildings in the United States and result in loss of more than 10 ..
  5. ULTRAVIOLET LIGHTS IN HVAC SYSTEMS--EFFECT ON HEALTH AND
    Dick Menzies; Fiscal Year: 1999
    Non specific building related illnesses or "sick building syndrome" are disorders of unknown cause that are estimated to affect 20-30 percent of workers in over one million buildings in the United States and result in loss of more than 10 ..
  6. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Cometto Muniz; Fiscal Year: 2000
    ..g., sick building syndrome) and occupational environments...
  7. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Cometto Muniz; Fiscal Year: 2001
    ..g., sick building syndrome) and occupational environments...
  8. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Cometto Muniz; Fiscal Year: 2002
    ..g., sick building syndrome) and occupational environments...
  9. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Cometto Muniz; Fiscal Year: 2003
    ..g., sick building syndrome) and occupational environments...
  10. TLR9 Mediated Dendritic Cell Responses in Hypersensitivity Pneumonitis
    Urvashi Bhan; Fiscal Year: 2009
    ..SC) is a dimorphic fungus that has been implicated in a number of respiratory illnesses, including "sick building syndrome", asthma, and HP...
  11. TLR9 Mediated Dendritic Cell Responses in Hypersensitivity Pneumonitis
    Urvashi Bhan; Fiscal Year: 2010
    ..SC) is a dimorphic fungus that has been implicated in a number of respiratory illnesses, including "sick building syndrome", asthma, and HP...
  12. A LABORATORY MODEL OF SICK BUILDING SYNDROME
    Robert Frank; Fiscal Year: 1991
    ..The term "sick building syndrome" (SBS) has been used to describe epidemics of symptoms or illness that occur in such workplaces and lack a ..
  13. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Cometto Muniz; Fiscal Year: 2007
    ..g., sick building syndrome and occupational settings) and outdoors (e.g...
  14. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Enrique Cometto Muniz; Fiscal Year: 2010
    ..g., sick building syndrome and occupational settings) and outdoors (e.g...
  15. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Cometto Muniz; Fiscal Year: 2009
    ..g., sick building syndrome and occupational settings) and outdoors (e.g...
  16. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Cometto Muniz; Fiscal Year: 2006
    ..g., sick building syndrome and occupational settings) and outdoors (e.g...
  17. Molecular Boundaries For Trigeminal Chemosensory Impact
    J Cometto Muniz; Fiscal Year: 2003
    ..e., irritation) and eye irritation, two frequently mentioned adverse symptoms arising from indoor (e.g., sick building syndrome) and occupational environments...
  18. Molecular Boundaries For Trigeminal Chemosensory Impact
    J Cometto Muniz; Fiscal Year: 2006
    ..e., irritation) and eye irritation, two frequently mentioned adverse symptoms arising from indoor (e.g., sick building syndrome) and occupational environments...
  19. Indoor Environment and Symptoms in Office Building
    MARK MENDELL; Fiscal Year: 2005
    ..abstract_text> ..
  20. Indoor Environment and Symptoms in Office Building
    MARK MENDELL; Fiscal Year: 2004
    ..abstract_text> ..
  21. INDIVIDUAL FACTORS IN NASAL IRRITANT SENSITIVITY
    Dennis Shusterman; Fiscal Year: 2002
    ....
  22. Lead Exposure, HPA Axis Dysfunction, and Blood Pressure: Hypertension Risk
    Nancy Fiedler; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  23. Mechanisms of Responses to Diesel Exhaust and Stress
    Robert Laumbach; Fiscal Year: 2008
    ..The experimental studies will contribute to elucidating mechanisms underlying CV effects of PM. ..
  24. Lead Exposure, HPA Axis Dysfunction, and Blood Pressure: Hypertension Risk
    Nancy Fiedler; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  25. Sunshine Education and Research Center
    Stuart Brooks; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  26. Mechanisms of Responses to Diesel Exhaust and Stress
    Robert Laumbach; Fiscal Year: 2007
    ..The experimental studies will contribute to elucidating mechanisms underlying CV effects of PM. ..
  27. Solvent Exposure: Functional Imaging and Behavior
    Nancy Fiedler; Fiscal Year: 2004
    ..abstract_text> ..
  28. Solvent Exposure: Functional Imaging and Behavior
    Nancy Fiedler; Fiscal Year: 2005
    ..abstract_text> ..
  29. Solvent Exposure: Functional Imaging and Behavior
    Nancy Fiedler; Fiscal Year: 2006
    ..abstract_text> ..