focal nodular hyperplasia

Summary

Summary: Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. The nodule, poorly encapsulated, consists of a central stellate fibrous scar and normal liver elements such as HEPATOCYTES, small BILE DUCTS, and KUPFFER CELLS among the intervening fibrous septa. The pale colored central scar represents large blood vessels with hyperplastic fibromuscular layer and narrowing lumen.

Top Publications

  1. ncbi High prevalence of hepatic focal nodular hyperplasia in subjects with hereditary hemorrhagic telangiectasia
    Elisabetta Buscarini
    Gastroenterology Department, Ospedale Maggiore, Crema, Italy
    Ultrasound Med Biol 30:1089-97. 2004
  2. ncbi Hepatocellular adenoma and focal nodular hyperplasia: value of gadoxetic acid-enhanced MR imaging in differential diagnosis
    Luigi Grazioli
    Department of Radiology, Institute of Hygiene, Epidemiology and Public Health, University of Brescia, Spedali Civili di Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy
    Radiology 262:520-9. 2012
  3. pmc Characterization of hepatic adenoma and focal nodular hyperplasia with gadoxetic acid
    Kiyarash Mohajer
    Department of Radiology, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, USA
    J Magn Reson Imaging 36:686-96. 2012
  4. ncbi P53 gene and Wnt signaling in benign neoplasms: beta-catenin mutations in hepatic adenoma but not in focal nodular hyperplasia
    Ya Wen Chen
    Graduate Institute of Molecular Medicine, National Taiwan University, Taipei, Taiwan
    Hepatology 36:927-35. 2002
  5. ncbi Pathological diagnosis of liver cell adenoma and focal nodular hyperplasia: Bordeaux update
    P Bioulac-Sage
    Hôpital St André, service d Hépatologie Gastroentérologie, CHU Bordeaux, 1 rue Jean Burguet, Bordeaux Cedex, France
    J Hepatol 46:521-7. 2007
  6. ncbi Immunohistochemical markers on needle biopsies are helpful for the diagnosis of focal nodular hyperplasia and hepatocellular adenoma subtypes
    Paulette Bioulac-Sage
    Department of Pathology, CHU Bordeaux, Hopital Pellegrin, Bordeaux, France
    Am J Surg Pathol 36:1691-9. 2012
  7. ncbi Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules
    Louis Libbrecht
    Department and Laboratories of Pathology, University and University Hospitals of Leuven, Leuven, Belgium
    Am J Surg Pathol 30:1405-11. 2006
  8. ncbi Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma
    Sandra Rebouissou
    INSERM, U674, Génomique fonctionnelle des tumeurs solides, Génétique des tumeurs hépatiques, Paris, France
    J Hepatol 48:163-70. 2008
  9. ncbi Imaging of atypical hemangiomas of the liver with pathologic correlation
    V Vilgrain
    Department of Radiology, Hopital Beaujon, Clichy, France
    Radiographics 20:379-97. 2000
  10. ncbi Accurate differentiation of focal nodular hyperplasia from hepatic adenoma at gadobenate dimeglumine-enhanced MR imaging: prospective study
    Luigi Grazioli
    Department of Radiology, University of Brescia, Spedali Civili di Brescia, Piazzale Spedali Civili 1, 25023 Brescia, Italy
    Radiology 236:166-77. 2005

Research Grants

Detail Information

Publications246 found, 100 shown here

  1. ncbi High prevalence of hepatic focal nodular hyperplasia in subjects with hereditary hemorrhagic telangiectasia
    Elisabetta Buscarini
    Gastroenterology Department, Ospedale Maggiore, Crema, Italy
    Ultrasound Med Biol 30:1089-97. 2004
    A vascular pathogenesis of hepatic focal nodular hyperplasia (FNH) has been suggested; this study was aimed to evaluate in families with hereditary hemorrhagic telangiectasia (HHT) the prevalence of FNH, relating it to presence and stage ..
  2. ncbi Hepatocellular adenoma and focal nodular hyperplasia: value of gadoxetic acid-enhanced MR imaging in differential diagnosis
    Luigi Grazioli
    Department of Radiology, Institute of Hygiene, Epidemiology and Public Health, University of Brescia, Spedali Civili di Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy
    Radiology 262:520-9. 2012
    To retrospectively evaluate the utility of gadoxetic acid-enhanced magnetic resonance (MR) imaging in the differential diagnosis of hepatocellular adenoma (HCA) and focal nodular hyperplasia (FNH).
  3. pmc Characterization of hepatic adenoma and focal nodular hyperplasia with gadoxetic acid
    Kiyarash Mohajer
    Department of Radiology, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, USA
    J Magn Reson Imaging 36:686-96. 2012
    To characterize imaging features of histologically proven hepatic adenoma (HA) as well as histologically and/or radiologically proven focal nodular hyperplasia (FNH) using delayed hepatobiliary MR imaging with 0.05 mmol/kg gadoxetic acid.
  4. ncbi P53 gene and Wnt signaling in benign neoplasms: beta-catenin mutations in hepatic adenoma but not in focal nodular hyperplasia
    Ya Wen Chen
    Graduate Institute of Molecular Medicine, National Taiwan University, Taipei, Taiwan
    Hepatology 36:927-35. 2002
    Hepatocellular adenoma (HA) and focal nodular hyperplasia (FNH) are 2 rare, benign liver neoplasms that often are discovered incidentally. To date, few genetic changes have been found in these 2 benign lesions...
  5. ncbi Pathological diagnosis of liver cell adenoma and focal nodular hyperplasia: Bordeaux update
    P Bioulac-Sage
    Hôpital St André, service d Hépatologie Gastroentérologie, CHU Bordeaux, 1 rue Jean Burguet, Bordeaux Cedex, France
    J Hepatol 46:521-7. 2007
  6. ncbi Immunohistochemical markers on needle biopsies are helpful for the diagnosis of focal nodular hyperplasia and hepatocellular adenoma subtypes
    Paulette Bioulac-Sage
    Department of Pathology, CHU Bordeaux, Hopital Pellegrin, Bordeaux, France
    Am J Surg Pathol 36:1691-9. 2012
    Phenotypic identification of focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) subtypes using immunohistochemical markers has been developed from their molecular characteristics...
  7. ncbi Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules
    Louis Libbrecht
    Department and Laboratories of Pathology, University and University Hospitals of Leuven, Leuven, Belgium
    Am J Surg Pathol 30:1405-11. 2006
    ..immunohistochemistry for GPC3 on 16 low-grade dysplastic nodules, 33 high-grade dysplastic nodules, 13 focal nodular hyperplasia-like nodules, and 59 HCCs with a diameter less or equal to 3 cm present in the cirrhotic liver of 66 ..
  8. ncbi Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma
    Sandra Rebouissou
    INSERM, U674, Génomique fonctionnelle des tumeurs solides, Génétique des tumeurs hépatiques, Paris, France
    J Hepatol 48:163-70. 2008
    b>Focal nodular hyperplasia (FNH) and hepatocellular adenomas (HCAs) are benign tumors that occur in otherwise normal liver parenchyma...
  9. ncbi Imaging of atypical hemangiomas of the liver with pathologic correlation
    V Vilgrain
    Department of Radiology, Hopital Beaujon, Clichy, France
    Radiographics 20:379-97. 2000
    ..Associated lesions include multiple hemangiomas, hemangiomatosis, focal nodular hyperplasia, and angiosarcoma...
  10. ncbi Accurate differentiation of focal nodular hyperplasia from hepatic adenoma at gadobenate dimeglumine-enhanced MR imaging: prospective study
    Luigi Grazioli
    Department of Radiology, University of Brescia, Spedali Civili di Brescia, Piazzale Spedali Civili 1, 25023 Brescia, Italy
    Radiology 236:166-77. 2005
    To prospectively determine the accuracy of differentiating benign focal nodular hyperplasia (FNH) from hepatic adenoma (HA) and liver adenomatosis (LA) by using gadobenate dimeglumine-enhanced magnetic resonance (MR) imaging.
  11. ncbi Benign nodular hepatocellular lesions caused by abnormal hepatic circulation: etiological analysis and introduction of a new concept
    F Kondo
    Department of Molecular Pathology, Chiba University School of Medicine, Chiba, Japan
    J Gastroenterol Hepatol 16:1319-28. 2001
    ..Of these lesions, focal nodular hyperplasia (FNH), nodular regenerative hyperplasia (NRH), nodular lesions associated with idiopathic portal ..
  12. ncbi Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis
    Shahid M Hussain
    Department of Radiology, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Radiographics 24:3-17; discussion 18-9. 2004
    b>Focal nodular hyperplasia (FNH) is the second most common benign liver tumor after hemangioma. FNH is classified into two types: classic (80% of cases) and nonclassic (20%)...
  13. ncbi Diagnostic accuracy of MRI in differentiating hepatocellular adenoma from focal nodular hyperplasia: prospective study of the additional value of gadoxetate disodium
    Matthanja Bieze
    Department of Surgery, Academic Medical Center, IWO 1 A1 132, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    AJR Am J Roentgenol 199:26-34. 2012
    ..of this article is to prospectively determine the sensitivity of hepatobiliary phase gadoxetate disodium-enhanced MRI combined with standard MRI in differentiating focal nodular hyperplasia (FNH) from hepatocellular adenoma (HCA).
  14. ncbi Focal nodular hyperplasia in children, adolescents, and young adults
    Alexander J Towbin
    Department of Radiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, ML 5031, Cincinnati, OH 45229, USA
    Pediatr Radiol 41:341-9. 2011
    b>Focal nodular hyperplasia (FNH) is a benign hepatic tumor that is rare in children...
  15. ncbi Focal nodular hyperplasia
    Valerie Vilgrain
    Department of Radiology, Hopital Beaujon, 100 bd du Général Leclerc, 92110 Clichy, France
    Eur J Radiol 58:236-45. 2006
    b>Focal nodular hyperplasia is the second most common benign liver tumor after hemangioma and occurs predominantly in young women. Imaging techniques are crucial in the diagnosis of this lesion...
  16. ncbi Differentiation of focal nodular hyperplasia and hepatocellular adenoma by contrast-enhanced ultrasound
    C F Dietrich
    1st Department of Internal Medicine, Caritas Hospital Bad Mergentheim, Uhlandstrasse 7, 97980 Bad Mergentheim, Germany
    Br J Radiol 78:704-7. 2005
    Non-invasive differentiation of focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) is difficult...
  17. pmc Characterization of focal liver lesions with SonoVue-enhanced sonography: international multicenter-study in comparison to CT and MRI
    Herve Trillaud
    Department of Radiology, University of Victor Segalen Bordeaux 2, CHU Bordeaux Hospital Saint André, 1 rue Jean Burguet, 33075 Bordeaux, France
    World J Gastroenterol 15:3748-56. 2009
    ..To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVue-enhancement; and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI)...
  18. ncbi Management of benign hepatic tumors
    Joseph F Buell
    Department of Surgery, Tulane Abdominal Transplant Institute, Tulane University, New Orleans, LA 70112, USA
    Surg Clin North Am 90:719-35. 2010
    ..Surgery should be limited to symptomatic benign tumors or those who have a risk for complication (hemorrhage, rupture, or degeneration). When surgery is indicated, patients with benign disease are the best candidates for laparoscopy...
  19. ncbi Telangiectatic focal nodular hyperplasia: a variant of hepatocellular adenoma
    Valerie Paradis
    Service d Anatomie Pathologique, Hopital Beaujon, Clichy, France
    Gastroenterology 126:1323-9. 2004
    Telangiectatic focal nodular hyperplasia" designate atypical lesions considered as variants of focal nodular hyperplasia (FNH)...
  20. ncbi Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence
    Emilio Quaia
    Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, Trieste 34149, Italy
    Radiology 232:420-30. 2004
    ....
  21. ncbi [Focal nodular hyperplasia of liver: a clinicopathologic study of 238 patients]
    Ling Li Chen
    Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Zhonghua Bing Li Xue Za Zhi 40:17-22. 2011
    To study the clinicopathologic features of focal nodular hyperplasia (FNH) of liver.
  22. ncbi Over-expression of glutamine synthetase in focal nodular hyperplasia: a novel easy diagnostic tool in surgical pathology
    Paulette Bioulac-Sage
    Department of Pathology, Hôpital Pellegrin CHU Bordeaux, Bordeaux, France
    Liver Int 29:459-65. 2009
    ..We investigated the use of GS as a marker in various clinical situations, in which FNH diagnosis had been firmly established to determine its contribution to diagnosis...
  23. ncbi Focal nodular hyperplasia and hepatic adenoma: epidemiology and pathology
    Lucas Maillette de Buy Wenniger
    Department of Gastroenterology and Hepatology, G4 213, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Dig Surg 27:24-31. 2010
    b>Focal nodular hyperplasia (FNH) and hepatic adenoma (HA) represent the most frequent non-vascular benign liver tumors. They are often asymptomatic...
  24. ncbi Dual time point C-11 acetate PET imaging can potentially distinguish focal nodular hyperplasia from primary hepatocellular carcinoma
    Li Huo
    Department of Nuclear Medicine, PET Center, Peking Union Medical College Hospital, Beijing, People s Republic of China
    Clin Nucl Med 34:874-7. 2009
    ..C-11 acetate PET in the diagnosis of hepatocellular carcinoma is that C-11 acetate also accumulates in focal nodular hyperplasia, which makes it challenging to distinguish hepatocellular carcinoma form focal nodular hyperplasia when ..
  25. ncbi Benign focal liver lesions: spectrum of findings on SonoVue-enhanced pulse-inversion ultrasonography
    Tommaso Vincenzo Bartolotta
    Department of Radiology, University of Palermo, Via del Vespro 127, 90127, Palermo, Italy
    Eur Radiol 15:1643-9. 2005
    ..This review illustrates the spectrum of enhancement patterns of BFLL on contrast-enhanced ultrasonography with SonoVue, a second-generation microbubble-based contrast agent...
  26. ncbi Orthotopic liver transplantation in glucose-6-phosphatase deficiency--Von Gierke disease--with multiple hepatic adenomas and concomitant focal nodular hyperplasia
    Gerson Carreiro
    Hepatology, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Brazil
    J Pediatr Endocrinol Metab 20:545-9. 2007
    ..b>Focal nodular hyperplasia (FNH) has never been described together with multiple adenomas in von Gierke disease...
  27. ncbi C-11 acetate does not enhance usefulness of F-18 FDG PET/CT in differentiating between focal nodular hyperplasia and hepatic adenoma
    Giulia Magini
    Dipartimento di Malattie Apparato Digerente e Medicina Interna, Alma Mater Studiorum, Universita di Bologna, Bologna, Italy
    Clin Nucl Med 34:659-65. 2009
    ..tomography (FDG PET) and C-11 acetate PET (AC PET) in distinguishing hepatic lesions due to consequential disease (hepatocellular adenoma and malignant lesions) from focal nodular hyperplasia (FNH) in patients at low risk of malignancy.
  28. ncbi 18F-fluorodeoxyglucose (FDG)-PET features of focal nodular hyperplasia (FNH) of the liver
    A Kurtaran
    Department of Nuclear Medicine, University of Vienna, Austria
    Liver 20:487-90. 2000
    The aim of this paper is to describe the imaging pattern of focal nodular hyperplasia (FNH) by l8F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET).
  29. pmc Focal nodular hyperplasia: hepatobiliary enhancement patterns on gadoxetic-acid contrast-enhanced MRI
    C S van Kessel
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Abdom Imaging 38:490-501. 2013
    To assess the range of hepatobiliary enhancement patterns of focal nodular hyperplasia (FNH) after gadoxetic-acid injection, and to correlate these patterns to specific histological features.
  30. ncbi Characteristics and distinguishing features of hepatocellular adenoma and focal nodular hyperplasia on gadoxetate disodium-enhanced MRI
    Andrei S Purysko
    Section of Abdominal Imaging, The Cleveland Clinic Foundation, Cleveland Clinic Main Campus, 9500 Euclid Ave, A21, Cleveland, OH 44195, USA
    AJR Am J Roentgenol 198:115-23. 2012
    ..this study is to evaluate the performance of gadoxetate disodium-enhanced MRI in the characterization of focal nodular hyperplasia (FNH) and hepatocellular adenoma and to assess potential advantages of hepatocyte phase imaging in ..
  31. ncbi Transarterial embolization using pingyangmycin lipiodol emulsion and polyvinyl alcohol for the treatment of focal nodular hyperplasia of the liver
    Dexiao Huang
    Department of Medical Imaging, Medical College of Shnatou University, Shantou, China
    Hepatogastroenterology 58:1736-41. 2011
    Surgical resection is the current treatment for focal nodular hyperplasia of the liver (FNH) when indicated. However, tumor location and size, patient comorbidities, and risk of complications may limit surgical options in some cases...
  32. ncbi Two cases of focal nodular hyperplasia of the liver: value of scintigraphy with Tc-99m GSA and positron emission tomography with FDG
    S Shiomi
    Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Ann Nucl Med 13:427-31. 1999
    b>Focal nodular hyperplasia (FNH) of the liver is relatively rare, and can be difficult to differentiate from other benign tumors arising in the liver. We describe a 23-year-old woman and a 25-year-old man with FNH...
  33. ncbi Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium
    Rajan T Gupta
    Department of Radiology, Duke University Medical Center, Durham, NC, USA
    AJR Am J Roentgenol 199:35-43. 2012
    The purpose of this article is to report the results from a multicenter retrospective MRI study comparing gadobenate dimeglumine and gadoxetate disodium for diagnosis of hepatic focal nodular hyperplasia (FNH).
  34. ncbi Focal nodular hyperplasia of the liver: diffusion and perfusion MRI characteristics
    Francescamaria Donati
    Department of Diagnostic Radiology, 2nd Unit of Radiology, Pisa University Hospital, 56124 Pisa, Italy
    Magn Reson Imaging 31:10-6. 2013
    To present diffusion and perfusion magnetic resonance imaging (MRI) characteristics of focal nodular hyperplasia (FNH) of the liver.
  35. ncbi Recent advances in cytogenetics and molecular biology of adult hepatocellular tumors: implications for imaging and management
    Alampady K Shanbhogue
    Department of Radiology, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA
    Radiology 258:673-93. 2011
    b>Focal nodular hyperplasia (FNH), hepatocellular adenoma (HCA), and hepatocellular carcinoma (HCC) compose hepatocellular neoplasms that occur in adults...
  36. ncbi Radiological and histopathological manifestations of hepatocellular nodular lesions concomitant with various congenital and acquired hepatic hemodynamic abnormalities
    Satoshi Kobayashi
    Department of Radiology, Kanazawa University School of Medicine, Kanazawa, 920 8641, Japan
    Jpn J Radiol 27:53-68. 2009
    ..Most of these nodular lesions are benign hyperplastic nodules, such as focal nodular hyperplasia, nodular regenerative hyperplasia, and other types of regenerative nodules...
  37. ncbi Multiple mixed adenoma-focal nodular hyperplasia of the liver associated with spontaneous intrahepatic porto-systemic shunt: a new type of vascular malformation associated with the multiple focal nodular hyperplasia syndrome?
    A Handra-Luca
    Histopathology 48:309-11. 2006
  38. ncbi Chromosomal analysis of hepatic adenoma and focal nodular hyperplasia by comparative genomic hybridization
    Yann Jang Chen
    Center for General Education, National Yang Ming University, Taipei, Taiwan
    Genes Chromosomes Cancer 35:138-43. 2002
    Hepatic adenoma (HA) and focal nodular hyperplasia (FNH) are two common non-malignant tumors of the liver. Genomic analysis on these benign lesions may shed light on the genetic mechanism underlying liver carcinogenesis...
  39. ncbi [Natural history of focal nodular hyperplasia. A retrospective study of 44 cases]
    V Vilgrain
    , , , France
    Gastroenterol Clin Biol 25:1008-10. 2001
    AIM: To evaluate the natural course of focal nodular hyperplasia according to hormonal status. METHODS: Forty-four patients were included in this retrospective study. Tumor size was assessed with ultrasound examination...
  40. ncbi Diagnosis of focal nodular hyperplasia. Role of imaging techniques
    Maurizio Soresi
    Dipartimento di Medicina Clinica e delle Patologie Emergenti, Universita degli Studi di Palermo
    Ann Ital Med Int 17:95-101. 2002
    b>Focal nodular hyperplasia (FNH) is a rare benign liver lesion which is difficult to differentiate from other benign liver pathologies and hepatocellular carcinoma...
  41. ncbi Focal nodular hyperplasia of the liver after intensive treatment for pediatric cancer: is hematopoietic stem cell transplantation a risk factor?
    Riccardo Masetti
    Paediatric Oncology and Haematology Unit Lalla Seràgnoli, University of Bologna Sant Orsola Malpighi Hospital, Bologna, Italy
    Eur J Pediatr 170:807-12. 2011
    b>Focal nodular hyperplasia (FNH) is a benign hepatic lesion very rarely described in the pediatric population...
  42. ncbi Hepatic focal nodular hyperplasia in children previously treated for a solid tumor. Incidence, risk factors, and outcome
    Celine Icher De Bouyn
    Pediatric Department, Institut Gustave Roussy, Villejuif, France
    Cancer 97:3107-13. 2003
    ..b>Focal nodular hyperplasia (FNH) of the liver is an uncommon, benign tumor in children and must be differentiated from malignant ..
  43. ncbi Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma
    Imran Ahmad
    Department of Pathology, Yale School of Medicine, PO Box 208023 New Haven, CT 06520 8023, USA
    Hum Pathol 40:726-34. 2009
    ..Distinct staining patterns using these markers have been shown in resected specimens of focal nodular hyperplasia, telangiectatic focal nodular hyperplasia, and hepatic adenoma...
  44. ncbi Prevalence of hepatic hemangioma in patients with focal nodular hyperplasia: MR imaging analysis
    Valerie Vilgrain
    Department of Radiology, Hopital Beaujon, Clichy, France
    Radiology 229:75-9. 2003
    To evaluate the prevalence of hepatic hemangioma in a large population of patients with focal nodular hyperplasia (FNH) and to determine if the prevalence is higher than that in patients with other hepatic masses.
  45. ncbi Diagnostic features of real-time contrast-enhanced ultrasound in focal nodular hyperplasia of the liver
    F Piscaglia
    Department of Clinical Medicine, Division of Internal Medicine, University of Bologna
    Ultraschall Med 31:276-82. 2010
    The typical appearance of focal nodular hyperplasia (FNH) in radiological contrast techniques (helical CT or MRI) includes homogeneous enhancement in the arterial phase, but the exact timing for the best visualization of this pattern is ..
  46. ncbi Focal nodular hyperplasia and hepatocellular adenoma of the liver: differentiation with multiphasic helical CT
    A J Ruppert-Kohlmayr
    Department of Radiology, University Hospital of Graz, Auenbruggerplatz 9, A-8036 Graz, Austria
    AJR Am J Roentgenol 176:1493-8. 2001
    OBJECTIVE: Differences of attenuation and enhancement patterns in focal nodular hyperplasia and hepatocellular adenoma were evaluated and quantified using triphasic single-slice helical CT...
  47. ncbi The clinical course in pediatric solid tumor patients with focal nodular hyperplasia of the liver
    Kiminobu Sugito
    Department of Pediatric Surgery, Nihon University School of Medicine, 30 1, Ohyaguchi Kamimachi, Itabashi ku, Tokyo, 173 8610, Japan
    Int J Clin Oncol 16:482-7. 2011
    b>Focal nodular hyperplasia (FNH) of the liver is a rare benign lesion that may be related to the vascular and hepatic damage induced by completion of tumor therapy and a reaction to localized vascular abnormality...
  48. ncbi Oral contraceptive use and focal nodular hyperplasia of the liver
    D Mathieu
    Department of Radiology, Henri Mondor Hospital, Assistance Publique Hopitaux de Paris, and Paris 12 University, Creteil, France
    Gastroenterology 118:560-4. 2000
    Because most patients with focal nodular hyperplasia (FNH) are young women, an important decision is whether to discontinue oral contraceptive (OC) use...
  49. ncbi Focal nodular hyperplasia and hepatic adenoma: a review
    Javier Lizardi-Cervera
    Gastroenterology and Liver Unit, Medica Sur Clinic and Foundation, Mexico City, Mexico
    Ann Hepatol 5:206-11. 2006
    b>Focal Nodular Hyperplasia (FNH) and Hepatic Adenoma (HA) are a benign tumors of the liver. The association with the use of oral contraception in women in middle age has been mentioned...
  50. ncbi Laparoscopic resection of focal nodular hyperplasia
    Joshua Felsher
    Department of General Surgery, George Washington University, Washington, DC, USA
    Surg Laparosc Endosc Percutan Tech 13:276-9. 2003
    b>Focal nodular hyperplasia (FNH) is a benign liver lesion incidentally discovered with increasing frequency because of the proliferation of imaging studies...
  51. ncbi Natural course of hepatic focal nodular hyperplasia: a long-term follow-up study with sonography
    Yuan Hung Kuo
    Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung University College of Medicine, 123 Ta Pei Road, Niao Sung 833 Kaohsiung, Taiwan
    J Clin Ultrasound 37:132-7. 2009
    We aimed to investigate the natural course of hepatic focal nodular hyperplasia (FNH) in a long-term follow-up study with sonography.
  52. ncbi Large spectrum of liver vascular lesions including high prevalence of focal nodular hyperplasia in patients with hereditary haemorrhagic telangiectasia: the Belgian Registry based on 30 patients
    Réginald Brenard
    Hepato Gastroenterology Unit, Grand Hôpital de Charleroi, Site St Joseph Gilly, Gilly, Belgium
    Eur J Gastroenterol Hepatol 22:1253-9. 2010
    ..We report the Belgian Registry of 30 patients (19 women and 11 men) with hereditary haemorrhagic telangiectasia (HHT) and liver involvement...
  53. ncbi Hepatic focal nodular hyperplasia developing in a Fanconi anemia patient: a case report and literature review
    Nabil M Nuamah
    Hacettepe University School of Medicine, Department of General Surgery, Sihhiye, Ankara 06100 Turkey
    Haematologica 91:ECR39. 2006
    ..Histopathological examination of the mass after right hepatic lobectomy revealed focal nodular hyperplasia. This appears to be the first reported case of a hepatic focal nodular hyperplasia of such proportion ..
  54. ncbi Focal nodular hyperplasia in pediatric patients with and without oncologic history
    Dalia Gobbi
    Pediatric Surgery Department, University Hospital of Padua, Padua, Italy
    Pediatr Blood Cancer 55:1420-2. 2010
    ..The lesion remained stable after the biopsy in 8 patients; no complications were observed in other 10 patients who underwent resection of the mass. The outcome of all our patients with or without previous oncological disease was benign...
  55. ncbi High serum level of alpha-fetoprotein in focal nodular hyperplasia of the liver
    Wadad Mneimneh
    Pathology Department, Beaujon Hospital, Clichy, France
    Pathol Int 61:491-4. 2011
    ..may increase in some benign conditions involving the liver but is usually within normal values in focal nodular hyperplasia (FNH) in adults...
  56. ncbi Use of X-chromosome inactivation pattern and laser microdissection to determine the clonal origin of focal nodular hyperplasia of the liver
    Li Gong
    Department of Pathology, Tangdu Hospital, The Fourth Military Medical University, Xi an, Shaanxi Province, China
    Pathology 41:348-55. 2009
    To determine the clonal origin of the whole lesion and each nodule of focal nodular hyperplasia (FNH) and elucidate its nature, simultaneously comparing the clonal composition with hepatocellular adenoma (HA).
  57. ncbi Contrast-enhanced ultrasonographic spoke-wheel sign in hepatic focal nodular hyperplasia
    Yi Hao Yen
    Division of Hepato Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, 123 Ta Pei Road, Kaohsiung 833, Taiwan
    Eur J Radiol 60:439-44. 2006
    ..To determine the utility of contrast-enhanced ultrasonography (CEUS) in assessing hepatic tumors with central feeding arteries found by color/power Doppler ultrasonograophy (CDUS/PDUS)...
  58. ncbi Plane and weighted tri-phase helical CT findings in the diagnosis of liver focal nodular hyperplasia
    Ai Min Xu
    Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China
    Hepatobiliary Pancreat Dis Int 1:219-23. 2002
    To analyze the pre- and post-contrast CT findings of liver focal nodular hyperplasia (FNH) so as to improve their diagnostic accuracy.
  59. ncbi Inferior caval vein thrombosis owing to compression of focal nodular hyperplasia: surgical resection after shrinkage by hepatic artery embolization
    Cora H P Arts
    Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Vascular 18:53-8. 2010
    The purpose of this study was to investigate the results of a staged treatment of symptomatic focal nodular hyperplasia (FNH), consisting of first embolization and then resection...
  60. ncbi Molecular characterization of the vascular features of focal nodular hyperplasia and hepatocellular adenoma: a role for angiopoietin-1
    Annette S H Gouw
    Pathology Section, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Hepatology 52:540-9. 2010
    b>Focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) are two hepatic nodular lesions of different etiologies...
  61. ncbi Focal nodular hyperplasia--a review of myths and truths
    Christopher B Nahm
    Upper Gastrointestinal Surgical Unit, Royal North Shore Hospital, St Leonards, NSW, 2065, Australia
    J Gastrointest Surg 15:2275-83. 2011
    b>Focal nodular hyperplasia (FNH) is a benign hyperplastic lesion of the liver with no known malignant potential. It has generated much interest due to the frequency with which it presents with atypical features on radiological imaging...
  62. ncbi Adenoma or atypical hepatic focal nodular hyperplasia: role of preoperative imaging and laparoscopic treatment
    Isidoro Di Carlo
    Department of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Catania, Italy
    Surg Laparosc Endosc Percutan Tech 20:e105-9. 2010
    Differentiation of focal nodular hyperplasia (FNH) and other hypervascular liver lesions, such as hepatocellular adenoma (HCA), is important because of the drastically different therapeutic approach...
  63. ncbi Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity
    Tommaso Vincenzo Bartolotta
    Department of Radiology, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy
    Eur Radiol 20:2248-56. 2010
    To correlate contrast-enhanced ultrasound (CEUS) findings of hepatic focal nodular hyperplasia (FNH) with lesion size, depth and liver echogenicity and to compare CEUS with baseline US.
  64. ncbi Focal nodular hyperplasia: lesion evaluation using 16-MDCT and 3D CT angiography
    Ihab R Kamel
    Russell H Morgan Department of Radiology, Johns Hopkins School of Medicine, 601 N Caroline St, Suite 3235A, Baltimore, MD 21287, USA
    AJR Am J Roentgenol 186:1587-96. 2006
    The purpose of this article is to present the imaging features of focal nodular hyperplasia (FNH) using MDCT and 3D CT angiography.
  65. ncbi Focal nodular hyperplasia or focal nodular hyperplasia-like lesions of the liver: a special emphasis on diagnosis
    Ji Young Choi
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Songpa Gu, Seoul, Korea
    J Gastroenterol Hepatol 26:1004-9. 2011
    b>Focal nodular hyperplasia (FNH) and FNH-like lesions are hypervascular masses that can mimic hepatocellular carcinoma (HCC)...
  66. ncbi Spontaneous regression of focal nodular hyperplasia of the liver
    Kenji Ohmoto
    Division of Gastroenterology, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Gastroenterol 37:849-53. 2002
    b>Focal nodular hyperplasia (FNH) of the liver is a rare benign lesion that probably reflects a local hyperplastic response of hepatocytes to a vascular abnormality. Currently, the natural history of the disease remains largely unknown...
  67. ncbi Telangiectatic focal nodular hyperplasia of the liver in the perinatal period: case report
    Nobuyoshi Okamura
    Cyto histopathology, Graduate School of Medical Science, Kitasato University, 1 15 1 Kitasato Sagamihara, Kanagawa 228 8555, Japan
    Pediatr Dev Pathol 8:581-6. 2005
    We report a case of congenital telangiectatic focal nodular hyperplasia, a rare variant form of the disease...
  68. ncbi Focal nodular hyperplasia in normal and fatty liver: a qualitative and quantitative evaluation with contrast-enhanced ultrasound
    Tommaso Vincenzo Bartolotta
    Department of Radiology, University of Palermo, Via del Vespro 127, 90127 Palermo, Italy
    Eur Radiol 14:583-91. 2004
    The aim of this study was to describe gray-scale appearance of liver parenchyma and focal nodular hyperplasia (FNH) by pulse inversion (PI) ultrasound (US) at baseline and after contrast agent administration in patients with normal and ..
  69. ncbi A case report of fetal telangiectatic focal nodular hyperplasia
    Jun Kang
    Pediatr Dev Pathol 10:416-7. 2007
  70. ncbi Focal nodular hyperplasia in children: clinical features and current management practice
    Timothy Lautz
    Department of Surgery, Children s Memorial Hospital, Feinberg School of Medicine of Northwestern University, Chicago, IL 60614, USA
    J Pediatr Surg 45:1797-803. 2010
    Although nonoperative management is an accepted practice for most adults with focal nodular hyperplasia (FNH), questions remain about the safety and feasibility of this strategy in children...
  71. ncbi Atypical focal nodular hyperplasia of the liver: imaging features of nonspecific and liver-specific MR contrast agents
    Ahmed Ba-Ssalamah
    Department of Radiology, University of Vienna, Waehringer Gurtel 18 20, A 1090 Vienna, Austria
    AJR Am J Roentgenol 179:1447-56. 2002
    The objective of our study was to describe the functional and differential uptake features of atypical focal nodular hyperplasia using different MR contrast agents and to evaluate their potential role in the diagnosis and ..
  72. ncbi Focal nodular hyperplasia of the liver: detection and characterization with plain and dynamic-enhanced MRI
    K J Mortele
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Abdom Imaging 27:700-7. 2002
    ..nonenhanced and dynamic gadolinium (Gd)-enhanced magnetic resonance imaging (MRI) appearances of hepatic focal nodular hyperplasia (FNH) as depicted with breath-hold MR sequences and assessed the detectability of the individual MR ..
  73. ncbi Management and surgical treatment for focal nodular hyperplasia in children
    Yuan Yang
    Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, 225 Changhai Road, 200438, Shanghai, China
    Pediatr Surg Int 24:699-703. 2008
    b>Focal nodular hyperplasia (FNH) is rare in pediatric liver tumor...
  74. pmc Combined hepatocellular and cholangiocellular carcinoma presenting with radiological characteristics of focal nodular hyperplasia
    Inneke Willekens
    Department of Radiology, UZ Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    World J Gastroenterol 15:3940-3. 2009
    ..We report a case of a cHCC-CC in a 47-year-old female that resembled focal nodular hyperplasia on Magnetic Resonance Imaging. Correlation of imaging and serum levels of alpha-fetoprotein and CA19...
  75. pmc Focal nodular hyperplasia of the liver: an unusual association with diabetes mellitus in a child and review of literature
    Piero Farruggia
    Unit of Pediatric Hematology and Oncology, G, Di Cristina Children s Hospital, and Department of Pediatrics, University of Palermo, Palermo, Italy
    Ital J Pediatr 36:41. 2010
    Hepatic hemangioma, adenoma and focal nodular hyperplasia are the most frequent benign lesions of the liver, but they are all infrequent among pediatric population...
  76. ncbi Unique hypervascular nodules in alcoholic liver cirrhosis: identical to focal nodular hyperplasia-like nodules?
    Osamu Nakashima
    Department of Pathology and Research Center of Innovative Cancer Therapy of the 21 Century COE Program for Medical Science, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    J Hepatol 41:992-8. 2004
    Currently, focal nodular hyperplasia (FNH)-like nodules in cirrhotic liver is spotlighted. Unique hypervascular nodules mimicking FNH-like nodule in alcoholic liver cirrhosis were clinicopathologically clarified.
  77. ncbi Focal nodular hyperplasia of the liver: usefulness of superparamagnetic iron oxide-enhanced magnetic resonance imaging
    Tadao Okada
    Department of Pediatric Surgery, 1st Surgery, Pediatrics, Pathology, Hokkaido University School of Medicine, Sapporo, 060 8638, Japan
    J Pediatr Surg 40:E21-5. 2005
    ..This report describes the use of superparamagnetic iron oxide-enhanced magnetic resonance imaging to diagnose fibronodular hyperplasia of the liver in a 12-year-old girl...
  78. pmc Focal nodular hyperplasia with concomitant hepatocellular carcinoma: a case report and clonal analysis
    S H Zhang
    Department of Pathology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China
    J Clin Pathol 57:556-9. 2004
    This report describes a hepatocellular carcinoma (HCC) with concomitant focal nodular hyperplasia (FNH) in a 56 year old Chinese man. There were two well circumscribed tumours measuring 3 x 2.5 x 2 cm and 2 x 1.5 x 1.5 cm...
  79. ncbi Evaluation of enhancement patterns of focal nodular hyperplasia in contrast-enhanced, wide-band phase-inversion harmonic power Doppler imaging of the liver
    Jacek Janica
    Department of Radiology, Medical University of Bialystok, Bialystok, Poland
    Med Sci Monit 10:17-21. 2004
    ..The purpose of the study was to assess the quality of performance of wideband, phase inversion harmonic power Doppler sonography in the diagnosis of focal nodular...
  80. ncbi The beta-catenin pathway is activated in focal nodular hyperplasia but not in cirrhotic FNH-like nodules
    Sandra Rebouissou
    INSERM, U674, Génomique fonctionnelle des tumeurs solides, 27 rue Juliette Dodu, Paris F 75010, France
    J Hepatol 49:61-71. 2008
    ..In contrast, FNH-like lesions/nodules occur in cirrhotic liver but share similar histopathological features. We conducted a transcriptome analysis to identify biological pathways deregulated in FNH...
  81. ncbi Imaging modalities for focal nodular hyperplasia and hepatocellular adenoma
    Jacomina W van den Esschert
    Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Dig Surg 27:46-55. 2010
    ..Differentiation between focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) is important because of the consequences for management...
  82. ncbi Clonality and TP53 mutation analysis of focal nodular hyperplasia of the liver
    Suqin Zheng
    Dept of Pathology and Laboratory Medicine, Indiana University, Indianapolis, 46202, USA
    Am J Clin Pathol 134:65-70. 2010
    b>Focal nodular hyperplasia (FNH) is considered a benign tumor of the liver. However, the biologic nature and clonality status of FNH are not well established...
  83. ncbi Tumor-specific vascularization pattern of liver metastasis, hepatocellular carcinoma, hemangioma and focal nodular hyperplasia in the differential diagnosis of 1,349 liver lesions in contrast-enhanced ultrasound (CEUS)
    D Strobel
    Internal Medicine I, University of Erlangen, Ulmenweg 18, 91058 Erlangen
    Ultraschall Med 30:376-82. 2009
    ..To evaluate the incidence and diagnostic accuracy of tumor-specific vascularization pattern in contrast-enhanced ultrasound (CEUS) in the differential diagnosis of liver tumors in clinical practice...
  84. pmc Clonality and allelotype analyses of focal nodular hyperplasia compared with hepatocellular adenoma and carcinoma
    Yi Ran Cai
    Department of Pathology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Panjiayuan Nanli 17, Beijing 100021, China
    World J Gastroenterol 15:4695-708. 2009
    To identify clonality and genetic alterations in focal nodular hyperplasia (FNH) and the nodules derived from it.
  85. ncbi MRI of focal nodular hyperplasia (FNH) with gadobenate dimeglumine (Gd-BOPTA) and SPIO (ferumoxides): an intra-individual comparison
    Luigi Grazioli
    Department of Radiology, University of Brescia, Brescia, Italy
    J Magn Reson Imaging 17:593-602. 2003
    To compare the efficacy of two different MR contrast agents for the detection and diagnosis of focal nodular hyperplasia (FNH).
  86. ncbi Management and algorithm for focal nodular hyperplasia of the liver in children
    T Okada
    Department of Pediatric Surgery, First Surgery, Radiology, Hokkaido University Graduate School of Medicine, and Hokkaido University Hospital, Pathology, Sapporo, Japan
    Eur J Pediatr Surg 16:235-40. 2006
    ..The aim of this study was to determine an appropriate management plan for childhood and adolescent FNH, in particular to establish an algorithm for preoperative diagnosis and treatment...
  87. ncbi Indications and long-term outcome of treatment for benign hepatic tumors: a critical appraisal
    T Terkivatan
    Department of Surgery, University Hospital Rotterdam Dijkzigt, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Arch Surg 136:1033-8. 2001
    ..The natural history and clinical behavior of benign hepatic tumors during long-term follow-up may not justify primary surgical treatment...
  88. ncbi CT and MR imaging evaluation of hepatic adenoma
    Giuseppe Brancatelli
    Sezione di Radiologia, Ospedale Specializzato in Gastroenterologia, Saverio de Bellis IRCCS, Castellana Grotte Bari, Italy
    J Comput Assist Tomogr 30:745-50. 2006
    ..The objective of our study was to illustrate the CT and MR imaging findings of hepatic adenoma...
  89. ncbi Congenital absence of the portal vein associated with focal nodular hyperplasia in the liver in an adult woman: imaging and review of the literature
    A M De Gaetano
    Department of Radiology, A Gemelli University Hospital, 8, Largo F Vito, Rome 00168, Italy
    Abdom Imaging 29:455-9. 2004
    We present a new case of congenital absence of the portal vein and focal nodular hyperplasia in the liver without additional congenital anomalies...
  90. ncbi A case report of hepatocellular carcinoma and focal nodular hyperplasia with a myelolipoma in two chimpanzees and a review of spontaneous hepatobiliary tumors in non-human primates
    Brian F Porter
    Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
    J Med Primatol 33:38-47. 2004
    ..Here we report a case of hepatic carcinoma and a case of hepatic focal nodular hyperplasia (FNH) and myelolipoma in two captive chimpanzees...
  91. pmc Different cytokeratin and neuronal cell adhesion molecule staining patterns in focal nodular hyperplasia and hepatic adenoma and their significance
    Anita Iyer
    Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA
    Hum Pathol 39:1370-7. 2008
    Differentiating focal nodular hyperplasia from hepatic adenoma can be challenging...
  92. ncbi Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients
    G Brancatelli
    Department of Radiology, University of Pittsburgh Medical Center, Presbyterian Hospital, 200 Lothrop St, Rm 4660 CHP MT, Pittsburgh, PA 15213-2582, USA
    Radiology 219:61-8. 2001
    PURPOSE: To evaluate features of focal nodular hyperplasia (FNH) at multiphasic helical computed tomography (CT). MATERIALS AND METHODS: Clinical, pathologic, and preoperative imaging findings were retrospectively reviewed in 78 patients...
  93. ncbi Congenital absence of the portal vein associated with focal nodular hyperplasia of the liver and congenital choledochal cyst: a case report
    T Kinjo
    First Department of Surgery, Ryukyu University School of Medicine, Nishihara-cho, Okinawa 903-0215, Japan
    J Pediatr Surg 36:622-5. 2001
    ..This case report describes a 3-year-old girl with a congenital absence of the portal vein, focal nodular hyperplasia (FNH) of the liver, and a congenital choledochal cyst (CCC)...
  94. ncbi Comparative genomic hybridization. Synchronous occurrence of focal nodular hyperplasia and hepatocellular carcinoma in the same liver is not based on common chromosomal aberrations
    Udo Kellner
    Dept of Pathology, Klinikum Minden, Friedrichstrasse 17, 32427 Minden, Germany
    Am J Clin Pathol 119:265-71. 2003
    ..Our findings support the notion that FNH is not a preneoplastic lesion for the occurrence of HCC in humans and that the synchronous occurrence of FNH and HCC is coincidental in our case...
  95. ncbi [Management of spontaneous hepatic hemorrhage due to focal nodular hyperplasia]
    Teófilo Cubo Cintas
    Servicio de Cirugia General y Aparato Digestivo, Hospital General, Ciudad Real, Espana
    Gastroenterol Hepatol 30:387-90. 2007
    b>Focal nodular hyperplasia is a benign liver tumor that usually follows an asymptomatic course. Hemorrhage of hepatic focal nodular hyperplasia is exceptional and occurs in tumors such as hepatocellular carcinoma and hepatic adenoma...
  96. ncbi [Multiple focal nodular hyperplasia of the liver associated with congenital absence of the portal vein]
    Sabine Schmidt
    Clinique des Maladies du Foie, hôpital de l Archet II, CHU, Nice
    Gastroenterol Clin Biol 30:310-3. 2006
    ..32nd case of congenital absence of portal vein in an 18-year-old female adult associated with multiple focal nodular hyperplasia of the liver...
  97. ncbi Nodular lymphoid lesion of the liver with simultaneous focal nodular hyperplasia and hemangioma: discrimination from primary hepatic MALT-type non-Hodgkin's lymphoma
    Klaus Willenbrock
    Senckenbergisches Institut für Pathologie, Klinikum der Johann Wolfgang Goethe Universitat, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Virchows Arch 448:223-7. 2006
    ..The diagnosis of NLL was made. In addition to NLL, focal nodular hyperplasia and hemangioma were detected...
  98. ncbi Focal nodular hyperplasia: morphologic and functional information from MR imaging with gadobenate dimeglumine
    L Grazioli
    Department of Radiology, University of Brescia, Spedali Civili di Brescia, Piazzale Spedali Civili 1, 25023 Brescia, Italy
    Radiology 221:731-9. 2001
    To determine whether gadobenate dimeglumine (Gd-BOPTA) is able to provide morphologic and functional information for characterization of focal nodular hyperplasia (FNH).
  99. ncbi Telangiectatic focal nodular hyperplasia: US, CT, and MR imaging findings with histopathologic correlation in 13 cases
    Patrick Attal
    Department of Radiology, Hopital Beaujon, Clichy, France
    Radiology 228:465-72. 2003
    ..US), computed tomographic (CT), and magnetic resonance (MR) imaging findings in 13 patients with telangiectatic focal nodular hyperplasia (FNH) and to compare imaging features with histopathologic results from resected specimens.
  100. ncbi Focal nodular hyperplasia of the liver in 86 patients
    Ying Hao Shen
    Department of Liver Surgery and Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Hepatobiliary Pancreat Dis Int 6:52-7. 2007
    b>Focal nodular hyperplasia (FNH), the second most common benign hepatic tumor after hemangioma, is characterized by a stellate central scar and hyperplastic nodules...
  101. ncbi A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia
    Valerie Paradis
    Service d Anatomie Pathologique and Service de Chirurgie, Hopital Beaujon, Clichy, France
    Gastroenterology 124:651-9. 2003
    Although the pathogenesis of focal nodular hyperplasia (FNH) of the liver remains unclear, a vascular mechanism has been suspected...

Research Grants1

  1. Race & Viral Resistance in Chronic Hepatitis C (VIRAHEP*
    Robert Brown; Fiscal Year: 2005
    ..abstract_text> ..