anus neoplasms

Summary

Summary: Tumors or cancer of the ANAL CANAL.

Top Publications

  1. ncbi Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis
    Dorothy A Machalek
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Lancet Oncol 13:487-500. 2012
  2. ncbi Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis
    Hugo De Vuyst
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Int J Cancer 124:1626-36. 2009
  3. doi Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions
    Brooke E Hoots
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599 7400, USA
    Int J Cancer 124:2375-83. 2009
  4. doi Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal
    Jose G Bazan
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Cancer 117:3342-51. 2011
  5. doi Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy
    Lisa A Kachnic
    Department of Radiation Oncology, Boston Medical Center, Boston, MA 02118, USA
    Int J Radiat Oncol Biol Phys 82:153-8. 2012
  6. ncbi Anal cancer incidence and survival: the surveillance, epidemiology, and end results experience, 1973-2000
    Lisa G Johnson
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer 101:281-8. 2004
  7. pmc Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11
    Edgar Ben-Josef
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
    J Clin Oncol 28:5061-6. 2010
  8. doi Trends in incidence of anal cancer and high-grade anal intraepithelial neoplasia in Denmark, 1978-2008
    Ann Nielsen
    Department of Viruses, Hormones and Cancer, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 130:1168-73. 2012
  9. ncbi Intensity-modulated radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis
    Joseph M Pepek
    Department of Radiation Oncology, Duke University School of Medicine, Durham, NC 27710, USA
    Int J Radiat Oncol Biol Phys 78:1413-9. 2010
  10. pmc Prognostic biomarkers in squamous cell carcinoma of the anus: a systematic review
    T Lampejo
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, Praed Street, London, W2 1NY, UK
    Br J Cancer 103:1858-69. 2010

Detail Information

Publications240 found, 100 shown here

  1. ncbi Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis
    Dorothy A Machalek
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Lancet Oncol 13:487-500. 2012
    ..We aimed to assess available data for anal HPV disease that can inform pre-cancer screening programmes...
  2. ncbi Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis
    Hugo De Vuyst
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Int J Cancer 124:1626-36. 2009
    ..This proportion would be similar for the corresponding high-grade lesions of the vagina and anus, but higher for VIN2/3 (75%) than for vulvar carcinoma...
  3. doi Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions
    Brooke E Hoots
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599 7400, USA
    Int J Cancer 124:2375-83. 2009
    ..If ongoing clinical trials show efficacy in preventing anal HPV infection and associated anal lesions, prophylactic HPV vaccines may play an important role for the primary prevention of these cancers in both genders...
  4. doi Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal
    Jose G Bazan
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Cancer 117:3342-51. 2011
    ....
  5. doi Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy
    Lisa A Kachnic
    Department of Radiation Oncology, Boston Medical Center, Boston, MA 02118, USA
    Int J Radiat Oncol Biol Phys 82:153-8. 2012
    ..Chemoradiation for anal cancer yields effective tumor control, but is associated with significant acute toxicity. We report our multi-institutional experience using dose-painted IMRT (DP-IMRT)...
  6. ncbi Anal cancer incidence and survival: the surveillance, epidemiology, and end results experience, 1973-2000
    Lisa G Johnson
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer 101:281-8. 2004
    ..Anal cancer is a rare malignancy of the anogenital tract that historically has affected women at a greater rate than men...
  7. pmc Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11
    Edgar Ben-Josef
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
    J Clin Oncol 28:5061-6. 2010
    ..To determine whether increased duration of radiation therapy (RT) and overall treatment (RX) time has a detrimental effect in anal cancer...
  8. doi Trends in incidence of anal cancer and high-grade anal intraepithelial neoplasia in Denmark, 1978-2008
    Ann Nielsen
    Department of Viruses, Hormones and Cancer, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 130:1168-73. 2012
    ..Our findings indicate that vaccines against HPV might play an important role in the prevention of anal cancer and its precursor lesions...
  9. ncbi Intensity-modulated radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis
    Joseph M Pepek
    Department of Radiation Oncology, Duke University School of Medicine, Durham, NC 27710, USA
    Int J Radiat Oncol Biol Phys 78:1413-9. 2010
    ..Intensity-modulated radiation therapy (IMRT) has the potential to reduce toxicities associated with chemoradiotherapy in the treatment of anal cancer. This study reports the results of using IMRT in the treatment of anal cancer...
  10. pmc Prognostic biomarkers in squamous cell carcinoma of the anus: a systematic review
    T Lampejo
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, Praed Street, London, W2 1NY, UK
    Br J Cancer 103:1858-69. 2010
    ..Further insight into tumour characteristics and molecular biology may identify novel therapeutic targets. This systematic review examines current prognostic markers in SCC of the anus...
  11. pmc Estimation of the epidemiological burden of human papillomavirus-related cancers and non-malignant diseases in men in Europe: a review
    Susanne Hartwig
    Department of Epidemiology, Sanofi Pasteur MSD, Lyon, France
    BMC Cancer 12:30. 2012
    ..The objective of this review is to estimate the epidemiological burden of HPV-related cancers and non-malignant diseases in men in Europe...
  12. ncbi Malignant transformation of high-grade anal intraepithelial neoplasia
    J H Scholefield
    Department of Surgery, Queens Medical Centre, Nottingham, UK
    Br J Surg 92:1133-6. 2005
    ..This makes management problematic as treatment options to eradicate the condition carry morbidity. The authors report their 10-year experience with conservative management of this condition, highlighting the lessons learnt...
  13. doi Trends in anal cancer in Australia, 1982-2005
    Fengyi Jin
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW 2010, Australia
    Vaccine 29:2322-7. 2011
    ..In order to understand the burden of potentially preventable anal cancer in Australia, we examine the incidence and survival from invasive anal SCC 1982-2005...
  14. doi The epidemiology of anal human papillomavirus and related neoplasia
    Joel M Palefsky
    Division of Infectious Disease, Department of Medicine, University of California, Box 0126, Room M1203, San Francisco, CA 94143, USA
    Obstet Gynecol Clin North Am 36:187-200. 2009
    ..This article describes the epidemiology of anal HPV infection, anal intraepithelial neoplasia, and anal cancer among men and women, as well as current efforts to prevent anal cancers...
  15. pmc Prognostic factors derived from a prospective database dictate clinical biology of anal cancer: the intergroup trial (RTOG 98-11)
    Jaffer A Ajani
    The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:4007-13. 2010
    ..A prognostic factor analysis for anal cancer from a prospective database has been published from only 1 study (N = 110). To confirm and uncover new prognostic factors, we analyzed the prospective database of intergroup RTOG 98-11...
  16. ncbi Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastro
    H Bartelink
    Department of Radiotherapy, The Netherlands Cancer Institute Antoni van Leeuwenhoek Huis, Amsterdam, The Netherlands
    J Clin Oncol 15:2040-9. 1997
    ....
  17. ncbi Growth factor receptor expression in anal squamous lesions: modifications associated with oncogenic human papillomavirus and human immunodeficiency virus
    Francine Walker
    Department of Pathology, Institut de la Santé et de la Recherche Médicale Unité773, Hopital Bichat Claude Bernard, 75018 Paris, France
    Hum Pathol 40:1517-27. 2009
    ..The finding that EGFR, c-Met, and VEGFR1 involved in carcinogenesis are well-represented and coexpressed in anal cancers, especially in HIV-positive population, suggests possible novel targeted treatments for anal diseases...
  18. pmc The economic burden of noncervical human papillomavirus disease in the United States
    Delphine Hu
    Program in Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Obstet Gynecol 198:500.e1-7. 2008
    ....
  19. doi Human papillomavirus genotypes in anal intraepithelial neoplasia and anal carcinoma as detected in tissue biopsies
    Anna K Wong
    Department of Pathology and Laboratory Medicine, George Burns and Gracie Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Mod Pathol 23:144-50. 2010
    ..In addition, a subset of these that were associated with type 16 or 18 showed progression, whereas those associated with non-16/18 subtypes regressed, thereby raising the possibility of conservative management for these lesions...
  20. ncbi Incidence of anal cancer in California: increased incidence among men in San Francisco, 1973-1999
    Rosemary D Cress
    California Cancer Registry, Sacramento, CA, USA
    Prev Med 36:555-60. 2003
    ..Incidence of anal cancer has increased in the United States during the past 30 years. This report describes the incidence of this rare cancer in the diverse California population...
  21. pmc Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas
    Robert J Myerson
    Department of Radiation Oncology, Washington University, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 74:824-30. 2009
    ..To develop a Radiation Therapy Oncology Group (RTOG) atlas of the elective clinical target volume (CTV) definitions to be used for planning pelvic intensity-modulated radiotherapy (IMRT) for anal and rectal cancers...
  22. ncbi Results of definitive irradiation in a series of 305 epidermoid carcinomas of the anal canal
    Elisabeth Deniaud-Alexandre
    Department of Radiation Oncology, Tenon Hospital A P H P, Paris, France
    Int J Radiat Oncol Biol Phys 56:1259-73. 2003
    ..To evaluate our data concerning the prognostic factors for locoregional control, survival, late complications, and sphincter conservation in a series of epidermoid cancers of the anal canal without clinical evidence of metastasis...
  23. ncbi Implantation of rectal cancer in an anal fistula: report of a case
    Satoshi Ishiyama
    Deparment of Surgery, Jikei University School of Medicine, Minato ku, Tokyo 105 8461, Japan
    Surg Today 36:747-9. 2006
    ..Although the recurrence of rectal cancer by mucosal implantation is not uncommon, the coincidental implantation of rectal cancer in an anal fistula is extremely rare...
  24. doi HAART and progression to high-grade anal intraepithelial neoplasia in men who have sex with men and are infected with HIV
    Alexandra de Pokomandy
    Department of Medicine and Immunodeficiency Service, McGill University Health Center, Montreal, Quebec, Canada
    Clin Infect Dis 52:1174-81. 2011
    ..The goal of this study was to identify risk factors associated with high-grade AIN (AIN-2,3) in HIV-positive MSM, including the receipt of highly active antiretroviral therapy (HAART)...
  25. ncbi Surgical management of primary anorectal melanoma
    P Pessaux
    Department of Surgery, Comprehensive Cancer Centre, Institut Gustave Roussy, Villejuif, France
    Br J Surg 91:1183-7. 2004
    ..This aim of this study was to analyse outcome after surgery for primary anorectal melanoma and to determine factors predictive of survival...
  26. ncbi Biology of HPV in HIV infection
    J Palefsky
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0126, USA
    Adv Dent Res 19:99-105. 2006
    ....
  27. ncbi High resolution anoscopy findings for men who have sex with men: inaccuracy of anal cytology as a predictor of histologic high-grade anal intraepithelial neoplasia and the impact of HIV serostatus
    Lori A Panther
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 38:1490-2. 2004
    ..The presence of any abnormal anal cytological finding indicates a potential for high-grade dysplasia on histological examination of MSM...
  28. ncbi Human papillomavirus anogenital disease in HIV-infected individuals
    Peter V Chin-Hong
    Department of Medicine, University of California, San Francisco 94143 0654, USA
    Dermatol Ther 18:67-76. 2005
    ..Prophylactic and therapeutic HPV vaccines are promising as future interventions for disease control in at-risk populations such as HIV-infected women and men...
  29. ncbi High prevalence of anal human papillomavirus infection and anal cancer precursors among HIV-infected persons in the absence of anal intercourse
    Christophe Piketty
    INSERM U 430 and Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Ann Intern Med 138:453-9. 2003
    ..Anal HPV infection and anal SIL are common in HIV-positive men who have sex with men; receptive anal intercourse is presumed to be the mode of acquisition of HPV...
  30. pmc Risk of anal cancer in HIV-infected and HIV-uninfected individuals in North America
    Michael J Silverberg
    Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA
    Clin Infect Dis 54:1026-34. 2012
    ..There are also conflicting data regarding calendar trends...
  31. ncbi Anal cancer: the end of the road for neoadjuvant chemoradiotherapy?
    Rob Glynne-Jones
    Mount Vernon Cancer Centre, Northwood, Middlesex, United Kingdom
    J Clin Oncol 26:3669-71. 2008
  32. pmc Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08
    Andre Konski
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 72:114-8. 2008
    ..Long-term efficacy and late toxicity reporting are the specific aims of this study...
  33. ncbi Malignant progression of anal intra-epithelial neoplasia
    Angus J M Watson
    Department of Surgery, Colorectal Unit, Christchurch Hospital, New Zealand
    ANZ J Surg 76:715-7. 2006
    ..This study reviews our experience with AIN, reviewing the incidence and risk factors for development of invasive malignancy and the outcome of present management strategies...
  34. ncbi Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer
    Janet R Daling
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer 101:270-80. 2004
    ..The incidence of anal cancer has increased among both men (160%) and women (78%) from 1973 to 2000 in the U.S. The authors conducted a population-based case-control study of anal cancer to examine factors that may account for this increase...
  35. ncbi Age-related prevalence of anal cancer precursors in homosexual men: the EXPLORE study
    Peter V Chin-Hong
    Department of Medicine, University of California San Francisco, CA 94143 0654, USA
    J Natl Cancer Inst 97:896-905. 2005
    ..The prevalence of cervical cancer precursor lesions peaks at around 30 years of age. The age-related prevalence of ASILs in HIV-negative MSM is unknown...
  36. ncbi Management of anal cancer in 2010. Part 1: Overview, screening, and diagnosis
    Ali Abbas
    School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Oncology (Williston Park) 24:364-9. 2010
    ..1% for localized anal cancer, 60.7% for regional disease, and 29.4% for metastatic disease. Part 2 of this two-part review will address the treatment of anal cancer, highlighting studies of chemoradiation...
  37. ncbi Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases
    M Miettinen
    Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Am J Surg Pathol 25:1121-33. 2001
    ..Intramural LMs are exceptional, and true LMSs are rare, and similar to colonic ones, often present as intraluminal polypoid masses that appear to have a better prognosis than GISTs with similar mitotic rates...
  38. ncbi Organ sparing by conformal avoidance intensity-modulated radiation therapy for anal cancer: dosimetric evaluation of coverage of pelvis and inguinal/femoral nodes
    Yi Jen Chen
    Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010 3000, USA
    Int J Radiat Oncol Biol Phys 63:274-81. 2005
    ....
  39. pmc Estimating the accuracy of anal cytology in the presence of an imperfect reference standard
    William C Mathews
    Department of Medicine, University of California San Diego, San Diego, California, United States of America AI 36214
    PLoS ONE 5:e12284. 2010
    ..The study aim is to estimate sensitivity and specificity of anal cytology for histologic HSIL in analyses adjusted for the imperfect biopsy reference standard...
  40. ncbi Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Mail Stop 426, Houston, Texas 77030, USA
    JAMA 299:1914-21. 2008
    ..Chemoradiation as definitive therapy is the preferred primary therapy for patients with anal canal carcinoma; however, the 5-year disease-free survival rate from concurrent fluorouracil/mitomycin and radiation is only approximately 65%...
  41. ncbi Squamous cell carcinoma of the anal canal
    Dennis L Rousseau
    Division of Surgical Oncology, Department of Surgery, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
    Surg Oncol 14:121-32. 2005
    ..The surgeon plays a key role in the diagnosis and follow-up of this disease. Surgical salvage with APR for disease persistence or recurrence in carefully selected patients can result in reasonable 5-year survivals...
  42. doi Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, Unit 426, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA
    Dig Dis Sci 55:1098-105. 2010
    ..Upon further expansion and validation, these results may provide a biomarker-based understanding of heterogeneous clinical biology of patients with anal carcinoma...
  43. ncbi Prevalence and risk factors for anal squamous intraepithelial lesions in women
    E A Holly
    Department of Epidemiology and Biostatistics, University of California, San Francisco 94143 1228, USA
    J Natl Cancer Inst 93:843-9. 2001
    ..Our aim was to determine the prevalence of human papillomavirus (HPV)-related abnormalities of the anal canal in women and to characterize risk factors for these lesions...
  44. doi Anal cancer and cervical cancer screening: key differences
    Teresa M Darragh
    Department of Pathology, University of California, San Francisco, CA, USA
    Cancer Cytopathol 119:5-19. 2011
    ..This article provides an overview of anal cancer screening while highlighting its differences from cervical cancer screening and the remaining obstacles and controversies to implementation of a successful anal cancer screening program...
  45. ncbi Oncologic outcomes of salvage surgery for epidermoid carcinoma of the anus initially managed with combined modality therapy
    Robert P Akbari
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Dis Colon Rectum 47:1136-44. 2004
    ..Primary chemoradiation failure for epidermoid carcinoma of the anus is treated by surgical resection. This study evaluates the outcome of salvage surgery at one institution...
  46. doi Performance characteristics of anal cytology and human papillomavirus testing in patients with high-resolution anoscopy-guided biopsy of high-grade anal intraepithelial neoplasia
    J Michael Berry
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Dis Colon Rectum 52:239-47. 2009
    ..High-resolution anoscopy with biopsy was used as the standard for detecting high-grade anal neoplasia and was compared to detection of high-grade anal neoplasia by anal cytology, human papillomavirus testing, or the combination...
  47. doi Beyond cervical cancer: burden of other HPV-related cancers among men and women
    Anil K Chaturvedi
    Division of Cancer Epidemiology and Genetics, Infections and Immunoepidemiology Branch, National Cancer Institute, Rockville, Maryland 20852, USA
    J Adolesc Health 46:S20-6. 2010
    ....
  48. ncbi Chemoradiotherapy in patients with anal cancer: impact of length of unplanned treatment interruption on outcome
    Andreas Meyer
    Department of Radiation Oncology, Medical School Hannover, Hannover, Germany
    Acta Oncol 45:728-35. 2006
    ..762), respectively. Chemoradiotherapy with short individualised treatment interruptions seems to be feasible with acceptable acute or late toxicities. Treatment is highly effective in terms of local control and colostomy-free survival...
  49. ncbi Anal carcinoma: incidence and effect of cumulative infections
    Iradj Sobhani
    FAMA de Colo Proctologie et INSERM U 410, Hopital Bichat Claude Bernard, Paris, France
    AIDS 18:1561-9. 2004
    ..Human papilloma virus (HPV) causes anal condyloma that is a risk factor for anal carcinoma. The incidence and mechanism of invasive anal carcinoma in patients with anal condyloma are prospectively determined...
  50. ncbi The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual HIV-positive men
    S J Goldie
    Center for Risk Analysis, Department of Health Policy and Management, Harvard School of Public Health, Boston, Mass 02115 5924, USA
    JAMA 281:1822-9. 1999
    ..Homosexual and bisexual men infected with human immunodeficiency virus (HIV) are at increased risk for human papillomavirus-related anal neoplasia and anal squamous cell carcinoma (SCC)...
  51. ncbi FHIT oncosuppressor gene expression profile in human anal cancers
    C Zucchini
    Molecular Genetics Research Center Fondazione CARISBO, Department of Histology, Embryology and Applied Biology, University of Bologna, Bologna, Italy
    Int J Biol Markers 22:39-42. 2007
    ..The absence or poor expression of the Fhit protein in anal cancers suggests a role for this tumor suppressor gene product, as a risk factor, in the onset of this human cancer, as reported before for other human gastrointestinal tumors...
  52. ncbi The impact of gap duration on local control in anal canal carcinoma treated by split-course radiotherapy and concomitant chemotherapy
    D C Weber
    Radiation Oncology Department of the University Hospital, Geneva, Switzerland
    Int J Radiat Oncol Biol Phys 50:675-80. 2001
    ..The present analysis suggests that shortening the gap contributes to optimizing LRC. Gaps longer than 5 weeks correlated with poorer LRC, with especially unsatisfactory results observed in younger patients...
  53. ncbi Synchronous carcinoma of the sigmoid colon and a perianal fistula
    Andrew P Zbar
    Dis Colon Rectum 47:544-5; author reply 545. 2004
  54. ncbi A population-based analysis of temporal trends in the incidence of squamous anal canal cancer in relation to the HIV epidemic
    Elizabeth Y Chiao
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Acquir Immune Defic Syndr 40:451-5. 2005
    ..The incidence of SCCA has particularly increased among men and those between 30 and 54 years of age since the introduction of HAART...
  55. ncbi Differential expression of anti-apoptotic protein Bcl-2 in keratinizing versus non-keratinizing squamous cell carcinoma of the anus
    Abdelkarim S Allal
    Division of Radiation Oncology, University Hospital Geneva, Rue Micheli du Crest 24, 1211 Geneva, Switzerland
    Int J Colorectal Dis 20:161-4. 2005
    ..The present study was undertaken to compare the expression of apoptosis-regulating proteins Bcl-2 and p53 in K versus NK SCCA...
  56. doi Performance of p16INK4a immunocytochemistry as a marker of anal squamous intraepithelial lesions
    Ivan Tramujas da Costa e Silva
    Postgraduation Program of Tropical Medicine Foundation of Amazonas University of the State of Amazonas, Manaus, Brazil, Department of Surgery, School of Medicine, Federal University of Amazonas, Manaus, Brazil
    Cancer Cytopathol 119:167-76. 2011
    ..This study examined measures of diagnostic validity of ICCp16 in HIV-positive patients treated at the Tropical Medicine Foundation of Amazonas in the coloproctology outpatient clinic...
  57. ncbi Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy
    Catherine Diamond
    Department of Medicine, Epidemiology Division, University of California Irvine, Orange, California 92868, USA
    Sex Transm Dis 32:314-20. 2005
    ..We sought to determine if the introduction of highly active antiretroviral therapy (HAART) corresponded with changes in anal squamous cell cancer rates among men with AIDS...
  58. ncbi Prognostic factors in anal carcinoma
    Claus Fenger
    Department of Pathology, Odense University Hospital, Denmark
    Pathology 34:573-8. 2002
    ..It is concluded that future research should concentrate on larger, probably multicentre series using standardised methods and criteria for evaluation...
  59. ncbi Metastatic anal cancer: the search for cure
    Bernard J Cummings
    Onkologie 29:5-6. 2006
  60. ncbi Ano-genital neoplasia in renal transplant patients
    F H Sillman
    Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Ann Transplant 2:59-66. 1997
    ..Next best is detecting HPV/intraepithelial neoplasia early with frequent inspection, cytology and liberal biopsies; and then removing any condylomas or intraepithelial neoplasia that develop...
  61. ncbi Distribution of HPV genotypes in Slovenian patients with anal carcinoma: preliminary results
    Kristina Fujs Komlos
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 20:141-3. 2011
    ..Prophylactic HPV vaccination with currently available vaccines could potentially prevent the great majority of anal cancers in Slovenia...
  62. ncbi Anal fibroadenoma: report of a common tumor type in an unusual location
    William W L Choi
    South Med J 100:914-5. 2007
  63. ncbi On the etiology of anal squamous carcinoma
    Morten Frisch
    Statens Serum Institut, Department of Epidemiological Research, Artillerivej 3, DK 2300 København S
    Dan Med Bull 49:194-209. 2002
    ..It this optimism is justified, the future may bring drastic reductions in the incidence of HPV-associated morbidities, including SC...
  64. doi Economic burden of anal cancer management in France
    L Abramowitz
    Proctology Unit, Bichat Hospital, 75018 Paris, France
    Rev Epidemiol Sante Publique 58:331-8. 2010
    ....
  65. ncbi Low acute toxicity of radiotherapy and radiochemotherapy in patients with cancer of the anal canal and HIV-infection
    S Hocht
    Abteilung Strahlentherapie, Universitätsklinikum Benjamin Franklin der Freien Universität Berlin, Germany
    Acta Oncol 36:799-802. 1997
    ..No excessive acute reactions were seen. Because of the short follow-up, late reactions and local control are not yet evaluable...
  66. ncbi ACT II: the second UK phase III anal cancer trial
    R James
    Clin Oncol (R Coll Radiol) 17:364-6. 2005
  67. ncbi High-dose radiation therapy and neoadjuvant plus concomitant chemotherapy with 5-fluorouracil and cisplatin in patients with locally advanced squamous-cell anal canal cancer: final results of a phase II study
    D Peiffert
    Centre Alexis Vautrin, Nancy, France
    Ann Oncol 12:397-404. 2001
    ..To analyse toxicity and response to a new scheme of neoadjuvant chemotherapy (CT) and concomitant radiochemotherapy (RT-CT) for locally advanced anal canal squamous-cell carcinoma (ACC)...
  68. ncbi Mitomycin C with continuous fluorouracil or with cisplatin in combination with radiotherapy for locally advanced anal cancer (European Organisation for Research and Treatment of Cancer phase II study 22011-40014)
    O Matzinger
    EORTC Headquarters, Brussels, Belgium
    Eur J Cancer 45:2782-91. 2009
    ..To assess the feasibility and activity of radio-chemotherapy with mitomycin C (MMC) and cisplatin (CDDP) in locally advanced squamous cell anal carcinoma with reference to radiotherapy (RT) combined with MMC and fluorouracil (5-FU)...
  69. ncbi Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study
    M Flam
    University of California, San Francisco, Fresno, USA
    J Clin Oncol 14:2527-39. 1996
    ....
  70. doi Intensity-modulated radiation therapy for the treatment of squamous cell anal cancer with para-aortic nodal involvement
    Joseph C Hodges
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 75:791-4. 2009
    ....
  71. pmc The impact of 18-fluorodeoxyglucose positron emission tomography on the staging, management and outcome of anal cancer
    E de Winton
    Department of Oncology, Royal United Hospital, Bath, UK
    Br J Cancer 100:693-700. 2009
    ..9%) and 55.3% (95% CI: 23.3-83.4%), respectively. FDG-PET shows increased sensitivity over CIm for staging nodal disease in anal cancer and changes treatment intent or radiotherapy prescription in a significant proportion of patients...
  72. doi Can the radiation dose to CT-enlarged but FDG-PET-negative inguinal lymph nodes in anal cancer be reduced?
    Sabine Kathrin Mai
    Department of Radiation Oncology, University Medical Center Mannheim, University of Heidelberg, Germany
    Strahlenther Onkol 185:254-9. 2009
    ..To investigate whether a dose reduction to CT-enlarged but FDG-PET-negative (([(18)F]-fluoro-2-deoxy-D-glucose positron emission tomography) inguinal lymph nodes in radiochemotherapy of anal cancer is safe...
  73. ncbi Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: toxicity and clinical outcome
    Michael T Milano
    Department of Radiation and Cellular Oncology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 63:354-61. 2005
    ..To assess survival, local control, and toxicity of intensity modulated radiation therapy (IMRT) in squamous cell carcinoma of the anal canal...
  74. ncbi A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy
    Kiran Devisetty
    Department of Radiation and Cellular Oncology, University of Chicago, IL, USA
    Radiother Oncol 93:298-301. 2009
    ..For V(30)>450 cc and < or =450 cc, acute GI toxicity was 33% and 8%, respectively (p=0.003)...
  75. doi Cetuximab-based treatment of metastatic anal cancer: correlation of response with KRAS mutational status
    Nadine Lukan
    III Medizinische Klinik, Universitatsmedizin Mannheim, Mannheim, Deutschland
    Oncology 77:293-9. 2009
    ..Anal cancers universally express the epidermal growth factor receptor (EGFR) and KRAS mutations have not been reported in anal cancer thus far...
  76. doi Surgical treatment for anorectal malignant melanoma: report of five cases and review of 79 Japanese cases
    Satoshi Ishizone
    Department of Surgery, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, 390 8621, Japan
    Int J Colorectal Dis 23:1257-62. 2008
    ..We also review the present five cases along with 74 other Japanese cases reported between 1997 and 2006 and discuss the role of surgery in the treatment of AMM...
  77. doi Long-term outcome after combined radiochemotherapy for anal cancer - retrospective analysis of efficacy, prognostic factors, and toxicity
    Sabine K Mai
    Department of Radiation Oncology, University Medical Center Mannheim, Germany
    Onkologie 31:251-7. 2008
    ..This retrospective study evaluated the efficacy, prognostic factors, and toxicity of combined radiochemotherapy for anal cancer...
  78. ncbi FDG-PET/CT in the evaluation of anal carcinoma
    Shane E Cotter
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 65:720-5. 2006
    ....
  79. ncbi Assessing the impact of FDG-PET in the management of anal cancer
    Brandon T Nguyen
    Radiation Oncology Centre, Austin Health, Vic, Australia
    Radiother Oncol 87:376-82. 2008
    ..To assess the utility of FDG-PET in anal cancer for staging and impact on radiotherapy planning (RTP), response and detection of recurrent disease...
  80. ncbi Factors affecting survival in patients with anal melanoma
    Yale D Podnos
    Department of General Oncologic Surgery, City of Hope National Medical Center, Duarte, California 91010, USA
    Am Surg 72:917-20. 2006
    ..Anal melanoma remains an uncommon but lethal disease. Extent of disease correlates with overall survival. Survival is improving, but the use and extent of operation are not associated with improved overall survival...
  81. ncbi Conformal therapy improves the therapeutic index of patients with anal canal cancer treated with combined chemotherapy and external beam radiotherapy
    Te Vuong
    Department of Radiation Oncology, McGill University Health Centre, Quebec, Canada
    Int J Radiat Oncol Biol Phys 67:1394-400. 2007
    ....
  82. ncbi Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy
    Loren K Mell
    Department of Radiation and Cellular Oncology, University of Chicago and University of Illinois at Chicago, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 70:1431-7. 2008
    ....
  83. ncbi Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience
    Joseph K Salama
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    J Clin Oncol 25:4581-6. 2007
    ..To report a multicenter experience treating anal canal cancer patients with concurrent chemotherapy and intensity-modulated radiation therapy (IMRT)...
  84. ncbi Anorectal amelanotic melanoma
    A Hillenbrand
    Department of General, Visceral, and Transplantation Surgery, University of Ulm, Ulm, Germany
    Colorectal Dis 10:612-5. 2008
    ..Anorectal melanoma is a rare, highly malignant tumour with a poor 5 year survival of 10%. Most anorectal melanomas have gross and/or histologic pigmentation, however about 30% of anorectal melanomas are amelanotic...
  85. ncbi Tumor response and survival predicted by post-therapy FDG-PET/CT in anal cancer
    Julie K Schwarz
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 71:180-6. 2008
    ..To evaluate the response to therapy for anal carcinoma using post-therapy imaging with positron emission tomography (PET)/computed tomography and F-18 fluorodeoxyglucose (FDG) and to compare the metabolic response with patient outcome...
  86. ncbi [Anal cancer in Iceland 1987-2003. A population based study]
    Halla Vietharsdóttir
    Department of Surgery, Iceland University Hospital, Hringbraut, 101 Reykjavik, Iceland
    Laeknabladid 92:365-72. 2006
    ..Anal cancer is a rare disease. The aim of this study was to describe anal cancer in Iceland in 1987-2003 with respect to incidence, histologic type, treatment, recurrence rate and survival...
  87. doi Lymphatic mapping and sentinel lymph node biopsy in epidermoid carcinoma of the anal canal
    S Gretschel
    Department of Surgery and Surgical Oncology, Charite, Universitatsmedizin Berlin, Campus Buch, Robert Rossle Klinik, HELIOS Klinikum Berlin, Berlin, Germany
    Eur J Surg Oncol 34:890-4. 2008
    ..Inguinal sentinel lymph node biopsy (SLNB) can be used to select patients appropriately for inguinal radiation. The study evaluates the efficiency and clinical impact of SLNB...
  88. ncbi Expression of epidermal growth factor receptor in squamous cell carcinomas of the anal canal is independent of gene amplification
    Gustavo Alvarez
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    Mod Pathol 19:942-9. 2006
    ..These observations may have important therapeutic implications since EGFR-based targeted therapies have shown promise for other malignant neoplasms...
  89. ncbi Tobacco smoking as a risk factor in anal carcinoma: an antiestrogenic mechanism?
    M Frisch
    Department of Epidemiology Research, Danish Epidemiology Science Center, Statens Serum Institut, Copenhagen
    J Natl Cancer Inst 91:708-15. 1999
    ..Smoking was recently suggested to increase the risk of anal cancer more in premenopausal women than in postmenopausal women. Thus, we used our population-based anal cancer case-control study in Denmark and Sweden to test this hypothesis...
  90. ncbi Wide local excision or abdominoperineal resection as the initial treatment for anorectal melanoma?
    John T Droesch
    Department of Surgery, University of Washington, 1959 N E Pacific St, Box 356410, Seattle, WA 98195 6410, USA
    Am J Surg 189:446-9. 2005
    ..Anorectal melanoma (AM) is a rare tumor with a poor prognosis. Treatment with abdominoperineal resection (APR) over wide local excision (WLE) is still debated. This study aimed to compare median survival of WLE and APR in patients with AM...
  91. ncbi Successful palliation of stenosing anorectal melanoma by intratumoral injections with natural interferon-beta
    A Ulmer
    Universitäts Hautklinik, Eberhard Karls Universitat, Liebermeisterstr 25, D 72076 Tubingen, Germany
    Melanoma Res 12:395-8. 2002
    ....
  92. ncbi Performance of anal cytology in a clinical setting when measured against histology and high-resolution anoscopy findings
    Mayura Nathan
    Department of Sexual Health, Homerton University Hospital NHS Foundation Trust, London E9 6SR, UK
    AIDS 24:373-9. 2010
    ..The success of cervical cytology in screening for cervical neoplasia has led to the concept of anal cytology screening for anal neoplasia. Our objective is to study the performance of anal cytology as a screening tool...
  93. ncbi Sentinel lymph node biopsy for squamous cell carcinoma of the anal canal
    Philippa Rabbitt
    University of Adelaide Department of Surgery, The Queen Elizabeth Hospital, South Australia, Australia
    ANZ J Surg 72:651-4. 2002
    ..We have developed a method of sampling the sentinel node in the groin using established node mapping techniques...
  94. ncbi Natural history and clinical management of anal human papillomavirus disease in men and women infected with human immunodeficiency virus
    Peter V Chin-Hong
    Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA 94143 0512, USA
    Clin Infect Dis 35:1127-34. 2002
    ..Treatment for AIN remains challenging, but AIN is easier to treat when the lesions are small, and it is likely that a screening program would identify affected individuals at an earlier stage of disease...
  95. ncbi Shortened irradiation scheme, continuous infusion of 5-fluorouracil and fractionation of mitomycin C in locally advanced anal carcinomas. Results of a phase II study of the European Organization for Research and Treatment of Cancer. Radiotherapy and Gastr
    J F Bosset
    Radiotherapy Department, Besancon University Hospital, Besancon, France
    Eur J Cancer 39:45-51. 2003
    ..The 22953 scheme is feasible and the results are promising. This is now considered as the new standard scheme by the EORTC...
  96. ncbi Carcinoma of the anal canal: a local experience and review of the literature
    Shirley Wong
    Department of Medical Oncology, Royal Melbourne Hospital, Victoria, Australia
    ANZ J Surg 74:541-6. 2004
    ..The aim of the present study is to determine how widely the combined modality approach has been adopted in routine clinical practice and what outcomes are achieved in this setting...
  97. ncbi Screening for anal dysplasia associated with human papillomavirus
    Wm Christopher Mathews
    University of California San Diego Medical Center, USA
    Top HIV Med 11:45-9. 2003
    ..This article summarizes a presentation given by Wm. Christopher Mathews, MD, MSPH, at the November 2002 International AIDS Society-USA course in San Diego...
  98. ncbi Epidermoid anal cancer: a review of a population-based series of 308 consecutive patients treated according to prospective protocols
    Per J Nilsson
    Centre of Gastrointestinal Disease, Ersta Hospital, Stockholm, Sweden
    Int J Radiat Oncol Biol Phys 61:92-102. 2005
    ..The use of neoadjuvant chemotherapy has been infrequently reported in the literature. This study presents results from a large population-based series and provides comparisons between different treatments...
  99. ncbi Contribution of conformal therapy in the treatment of anal canal carcinoma with combined chemotherapy and radiotherapy: results of a phase II study
    Te Vuong
    Department of Radiation Oncology, McGill University Health Centre, Montreal, Quebec, Canada
    Int J Radiat Oncol Biol Phys 56:823-31. 2003
    ..To evaluate the feasibility of delivering conformal radiotherapy (RT) and concurrent chemotherapy without a mandatory break in patients with anal canal carcinoma...
  100. ncbi Biochemotherapy in patients with metastatic anorectal mucosal melanoma
    Kevin B Kim
    Department of Melanoma Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston Texas 77030, USA
    Cancer 100:1478-83. 2004
    ..Patients with metastatic anorectal melanoma generally have an unfavorable prognosis, but no effective systemic therapy has been reported...
  101. ncbi Cancer of the anal canal
    Matthew A Clark
    Department of General Surgery, Middlemore Hospital, Otahuhu, Auckland, New Zealand
    Lancet Oncol 5:149-57. 2004
    ..Future challenges will be influenced by an increasing incidence due to human papillomavirus and HIV infection, more accurate characterisation and treatment of early (in situ) disease, and optimisation of chemoradiation regimens...

Research Grants107 found, 100 shown here

  1. Strategies Against HPV Related Genital Diseases in Women
    Bradley Monk; Fiscal Year: 2006
    ..It is expected that Dr. Monk will have obtained extramural funding for both his laboratory and clinical studies by the end of the period of support requested. ..
  2. Effect of Oxidant Load on HPV Persistence and CIN (SIL)
    Anna Giuliano; Fiscal Year: 2007
    ..abstract_text> ..
  3. Prediction of Pathologic Complete Response by Gene Expression Profiling in Esopha
    Jaffer A Ajani; Fiscal Year: 2010
    ..Our goal is to pave the way for a strategy in the future that will allow administration of effective therapy, improve safety, and preserve the esophagus in some patients. ..
  4. Anogenital HPV Infection in a Population-Based Sample of Puerto Rican Women
    Ana Patricia Ortiz; Fiscal Year: 2010
    ....
  5. The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
    Elizabeth Chiao; Fiscal Year: 2009
    ....
  6. The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
    Elizabeth Chiao; Fiscal Year: 2006
    ....
  7. The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
    Elizabeth Chiao; Fiscal Year: 2010
    ....
  8. The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
    Elizabeth Chiao; Fiscal Year: 2009
    ....
  9. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2001
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  10. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2004
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  11. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2005
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  12. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2002
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  13. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV-INFECTED MEN
    Joel Palefsky; Fiscal Year: 1993
    ..These studies may therefore provide valuable information relevant to other diseases as well, such as cancer of the cervix...
  14. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV-INFECTED MEN
    Joel Palefsky; Fiscal Year: 1992
    ..These studies may therefore provide valuable information relevant to other diseases as well, such as cancer of the cervix...
  15. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2005
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  16. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV INFECTED MEN
    Joel Palefsky; Fiscal Year: 2001
    ....
  17. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2003
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  18. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2002
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  19. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV INFECTED MEN
    Joel Palefsky; Fiscal Year: 2002
    ....
  20. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2004
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  21. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2003
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  22. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2001
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  23. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2003
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  24. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2004
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  25. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV-INFECTED MEN
    Joel Palefsky; Fiscal Year: 1991
    ..These studies may therefore provide valuable information relevant to other diseases as well, such as cancer of the cervix...
  26. Molecular Markers of Response to Chemoradiation in Localized Esophageal Cancer
    Jaffer Ajani; Fiscal Year: 2008
    ..Our goal is to pave the way for a strategy in the future that will allow administration of effective therapy, improve safety, and preserve the esophagus in some patients. ..
  27. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV INFECTED MEN
    Joel Palefsky; Fiscal Year: 1999
    ....
  28. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV INFECTED MEN
    Joel Palefsky; Fiscal Year: 2000
    ....
  29. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2006
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  30. Anal Dysplasia in HIV+ and HIV- men
    Timothy Wilkin; Fiscal Year: 2006
    ..This study will help provide important new information on which groups of HIV+ men may benefit from screening and how HAART may modify this risk. ..
  31. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1991
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development...
  32. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2004
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  33. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2002
    ..abstract_text> ..
  34. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2000
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  35. HIV Infection, Antiretroviral Therapy, Cancer Incidence and Progression
    Michael Silverberg; Fiscal Year: 2008
    ..The results of this research may be informative to those providing care to HIV-infected patients with or at-risk for cancer. ..
  36. A San Francisco Street Youth Cohort: At Risk and HIV+
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..We believe it is critical to continue to engage the high risk youth in the San Francisco Bay Area in clinical and behavioral research. ..
  37. HIV Infection, Antiretroviral Therapy, Cancer Incidence and Progression
    Michael Silverberg; Fiscal Year: 2007
    ..The results of this research may be informative to those providing care to HIV-infected patients with or at-risk for cancer. ..
  38. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2003
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  39. Natural History of HPV Infection to Neoplasia
    Anna Barbara Moscicki; Fiscal Year: 2008
    ..Information garnered from this type of study will be critical in developing vaccine strategies and therapies as well as illuminating immune responses developed in the mucosal epithelium. ..
  40. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1992
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development...
  41. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1990
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development...
  42. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2004
    ..abstract_text> ..
  43. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..S. and specifically assess how best to modify cytology-based screening, utilize HPV diagnostics, and tailor aoDrooriate follow-uo strategies for adolescents and vouna women diaanosed with CIN 2 ..
  44. Natural History of HPV Infection to Neoplasia
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..Information garnered from this type of study will be critical in developing vaccine strategies and therapies as well as illuminating immune responses developed in the mucosal epithelium. ..
  45. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2002
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  46. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2003
    ..abstract_text> ..
  47. The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
    Elizabeth Chiao; Fiscal Year: 2008
    ....
  48. The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
    Elizabeth Chiao; Fiscal Year: 2007
    ....
  49. MOLECULAR EPIDEMIOLOGY OF LUNG CANCER
    Chu Chen; Fiscal Year: 2009
    ..g. Rosaceae fruits and Cruciferae vegetables), and food-derived nutrients (e.g. carotenoids, vitamin C, and vitamin E). ..
  50. CALCIUM CHANNEL BLOCKERS IN BREAST CANCER ETIOLOGY
    Janet Daling; Fiscal Year: 1999
    ..cimetidine, anti-depressants, lipid lowering drugs) frequently used by women in this age group. ..
  51. Human papillomavirus as a risk factor for HIV infection
    PETER CHIN HONG; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  52. MOLECULAR EPIDEMIOLOGY OF LUNG CANCER
    Chu Chen; Fiscal Year: 2008
    ..g. Rosaceae fruits and Cruciferae vegetables), and food-derived nutrients (e.g. carotenoids, vitamin C, and vitamin E). ..
  53. Molecular Epidemiology of Endometrial Cancer
    Chu Chen; Fiscal Year: 2005
    ..Efforts will also be devoted to generating risk indices through statistical modeling that integrate potential effects of genetic variants in the estrogen metabolism pathway and/or DNA repair pathways. ..
  54. BREAST CANCER AND GENE POLYMORPHISMS IN CHINESE WOMEN
    Chu Chen; Fiscal Year: 2001
    ..Our ultimate goal is to provide information to identify women at high risk of breast cancer, and to aid in the formulation of prevention strategies for these women. ..
  55. HRT USE AND RISK OF LOBULAR AND DUCTAL BREAST CANCER
    Janet Daling; Fiscal Year: 2002
    ..of CHRT associated with alteration in the histologic characteristics, tumor cell proliferation, or expression of steroid hormone receptors, oncogenes, and cell cycle and cell death regulator proteins of lobular and ductal breast cancers? ..
  56. MOLECULAR EPIDEMIOLOGY OF LUNG CANCER
    Chu Chen; Fiscal Year: 2010
    ..g. Rosaceae fruits and Cruciferae vegetables), and food-derived nutrients (e.g. carotenoids, vitamin C, and vitamin E). ..
  57. BREAST CANCER AND GENE POLYMORPHISMS IN CHINESE WOMEN
    Chu Chen; Fiscal Year: 2002
    ..Our ultimate goal is to provide information to identify women at high risk of breast cancer, and to aid in the formulation of prevention strategies for these women. ..
  58. Clinical & Cost-Effectiveness of Cervical CA Screening
    Sue Goldie; Fiscal Year: 2002
    ..The proposed analyses will provide important information to clinicians, public health providers, and policy makers in both the national and international arena. ..
  59. Clinical & Cost Effectiveness of HPV Vaccination in the US
    Sue Goldie; Fiscal Year: 2009
    ....
  60. BREAST CANCER AND GENE POLYMORPHISMS IN CHINESE WOMEN
    Chu Chen; Fiscal Year: 2003
    ..Our ultimate goal is to provide information to identify women at high risk of breast cancer, and to aid in the formulation of prevention strategies for these women. ..
  61. Breast and Prostate Cancer Patterns of Care
    Rosemary Cress; Fiscal Year: 2007
    ..What is learned about treatment quality and completeness can subsequently be used to improve the information in these registries so that they can become a resource for researchers evaluating quality of cancer care. ..
  62. FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDY
    Anna Giuliano; Fiscal Year: 2001
    ..C-peptide, glycosylated hemoglobin, IGF-1, and IGFBP3 will be evaluated with respect to breast and endometrial cancer in a subset of women. ..
  63. Effect of Oxidant Load on HPV Persistence and CIN (SIL)
    Anna Giuliano; Fiscal Year: 2008
    ..abstract_text> ..
  64. FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDY
    Anna Giuliano; Fiscal Year: 1999
    ..C-peptide, glycosylated hemoglobin, IGF-1, and IGFBP3 will be evaluated with respect to breast and endometrial cancer in a subset of women. ..
  65. Planning Grant: Cancer Research Training in Morocco
    Anna Giuliano; Fiscal Year: 2009
    ..S. and in Morocco, and support cancer that will benefit the U.S. through elucidation of cancer risk factors and cancer disease progression.. ..
  66. Natural History of HPV Infection in Men: The HIM Study
    Anna Giuliano; Fiscal Year: 2008
    ..abstract_text> ..
  67. Natural History of HPV Infection in Men: The HIM Study
    Anna R Giuliano; Fiscal Year: 2010
    ....
  68. Natural History of HPV Infection in Men: The HIM Study
    Anna R Giuliano; Fiscal Year: 2011
    ....
  69. Natural History of HPV Infection in Men: The HIM Study
    Anna Giuliano; Fiscal Year: 2007
    ..abstract_text> ..
  70. FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDY
    Anna Giuliano; Fiscal Year: 2002
    ..C-peptide, glycosylated hemoglobin, IGF-1, and IGFBP3 will be evaluated with respect to breast and endometrial cancer in a subset of women. ..
  71. Natural History of HPV Infection in Men: The HIM Study
    Anna Giuliano; Fiscal Year: 2005
    ..abstract_text> ..
  72. Effect of Oxidant Load on HPV Persistence and CIN (SIL)
    Anna Giuliano; Fiscal Year: 2006
    ..abstract_text> ..
  73. HPV methylation: a biomarker of cervical lesion progress
    Anna Giuliano; Fiscal Year: 2003
    ..Results from this study may provide a novel biomarker for women at risk of progression of HPV infection to SIL. ..
  74. FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDY
    Anna Giuliano; Fiscal Year: 2000
    ..C-peptide, glycosylated hemoglobin, IGF-1, and IGFBP3 will be evaluated with respect to breast and endometrial cancer in a subset of women. ..
  75. Natural History of HPV Infection in Men: The HIM Study
    Anna Giuliano; Fiscal Year: 2006
    ..abstract_text> ..
  76. Cidofovir for Perianal Dysplasia in HIV Patients
    Elizabeth Stier; Fiscal Year: 2006
    ..Novel treatments, such as topical cidofovir, may prevent pre-cancerous lesions from developing into cancer in HIV-infected patients. ..
  77. ANTIOXIDANTS NUTRIENTS AMONG A BRAZILIAN POPULATION
    Anna Giuliano; Fiscal Year: 2000
    ..Results from this study will efficiently further our understanding of the role of antioxidant nutrients and cervical carcinogens. ..
  78. Effect of Oxidant Load on HPV Persistence and CIN (SIL)
    Anna Giuliano; Fiscal Year: 2004
    ..abstract_text> ..
  79. ANTIOXIDANTS NUTRIENTS AMONG A BRAZILIAN POPULATION
    Anna Giuliano; Fiscal Year: 2001
    ..Results from this study will efficiently further our understanding of the role of antioxidant nutrients and cervical carcinogens. ..
  80. ANTIOXIDANTS NUTRIENTS AMONG A BRAZILIAN POPULATION
    Anna Giuliano; Fiscal Year: 2002
    ..Results from this study will efficiently further our understanding of the role of antioxidant nutrients and cervical carcinogens. ..
  81. Natural History of HPV Infection in Men: The HIM Study
    Anna Giuliano; Fiscal Year: 2004
    ..abstract_text> ..
  82. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2001
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  83. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2001
    ..abstract_text> ..