anus neoplasms

Summary

Summary: Tumors or cancer of the ANAL CANAL.

Top Publications

  1. ncbi Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis
    Dorothy A Machalek
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Lancet Oncol 13:487-500. 2012
  2. ncbi HPV vaccine against anal HPV infection and anal intraepithelial neoplasia
    Joel M Palefsky
    Department of Medicine, University of California at San Francisco, Box 0654, San Francisco, CA 94143, USA
    N Engl J Med 365:1576-85. 2011
  3. ncbi Anal cancer incidence and survival: the surveillance, epidemiology, and end results experience, 1973-2000
    Lisa G Johnson
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer 101:281-8. 2004
  4. ncbi Trends in anal cancer in Australia, 1982-2005
    Fengyi Jin
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW 2010, Australia
    Vaccine 29:2322-7. 2011
  5. ncbi Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal
    Jose G Bazan
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Cancer 117:3342-51. 2011
  6. pmc Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I)
    J Northover
    St Mark s Hospital, Northwick Park, Watford Road, Harrow, Middlesex HA1 3UJ, UK
    Br J Cancer 102:1123-8. 2010
  7. ncbi Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis
    Hugo De Vuyst
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Int J Cancer 124:1626-36. 2009
  8. pmc Incidence and epidemiology of anal cancer in the multicenter AIDS cohort study
    Gypsyamber D'Souza
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 48:491-9. 2008
  9. ncbi Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy
    Lisa A Kachnic
    Department of Radiation Oncology, Boston Medical Center, Boston, MA 02118, USA
    Int J Radiat Oncol Biol Phys 82:153-8. 2012
  10. pmc Risk factors for anogenital human papillomavirus infection in men
    Carrie M Nielson
    Arizona Cancer Center and Mel and Enid Zuckerman College of Public Health, Tucson, AZ, USA
    J Infect Dis 196:1137-45. 2007

Detail Information

Publications274 found, 100 shown here

  1. ncbi Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis
    Dorothy A Machalek
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Lancet Oncol 13:487-500. 2012
    ..We aimed to assess available data for anal HPV disease that can inform pre-cancer screening programmes...
  2. ncbi HPV vaccine against anal HPV infection and anal intraepithelial neoplasia
    Joel M Palefsky
    Department of Medicine, University of California at San Francisco, Box 0654, San Francisco, CA 94143, USA
    N Engl J Med 365:1576-85. 2011
    ..We studied the safety and efficacy of quadrivalent HPV vaccine (qHPV) against anal intraepithelial neoplasia associated with HPV-6, 11, 16, or 18 infection in men who have sex with men...
  3. ncbi Anal cancer incidence and survival: the surveillance, epidemiology, and end results experience, 1973-2000
    Lisa G Johnson
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer 101:281-8. 2004
    ..Anal cancer is a rare malignancy of the anogenital tract that historically has affected women at a greater rate than men...
  4. ncbi Trends in anal cancer in Australia, 1982-2005
    Fengyi Jin
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW 2010, Australia
    Vaccine 29:2322-7. 2011
    ..In order to understand the burden of potentially preventable anal cancer in Australia, we examine the incidence and survival from invasive anal SCC 1982-2005...
  5. ncbi Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal
    Jose G Bazan
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Cancer 117:3342-51. 2011
    ....
  6. pmc Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I)
    J Northover
    St Mark s Hospital, Northwick Park, Watford Road, Harrow, Middlesex HA1 3UJ, UK
    Br J Cancer 102:1123-8. 2010
    ..Patients in this trial have now been followed up for a median of 13 years...
  7. ncbi Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis
    Hugo De Vuyst
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Int J Cancer 124:1626-36. 2009
    ..This proportion would be similar for the corresponding high-grade lesions of the vagina and anus, but higher for VIN2/3 (75%) than for vulvar carcinoma...
  8. pmc Incidence and epidemiology of anal cancer in the multicenter AIDS cohort study
    Gypsyamber D'Souza
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 48:491-9. 2008
    ..To examine the incidence and risk factors for anal cancer in a multicenter cohort of human immunodeficiency virus (HIV) positive and HIV-negative men who have sex with men followed between 1984 and 2006 (Multicenter AIDS Cohort Study)...
  9. ncbi Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy
    Lisa A Kachnic
    Department of Radiation Oncology, Boston Medical Center, Boston, MA 02118, USA
    Int J Radiat Oncol Biol Phys 82:153-8. 2012
    ..Chemoradiation for anal cancer yields effective tumor control, but is associated with significant acute toxicity. We report our multi-institutional experience using dose-painted IMRT (DP-IMRT)...
  10. pmc Risk factors for anogenital human papillomavirus infection in men
    Carrie M Nielson
    Arizona Cancer Center and Mel and Enid Zuckerman College of Public Health, Tucson, AZ, USA
    J Infect Dis 196:1137-45. 2007
    ..Human papillomavirus (HPV) is strongly associated with cervical and other anogenital cancers. Identification of risk factors for HPV infection in men may improve our understanding of HPV transmission and prevention...
  11. pmc Comparative accuracy of anal and cervical cytology in screening for moderate to severe dysplasia by magnification guided punch biopsy: a meta-analysis
    Wm Christopher Mathews
    Department of Medicine, University of California San Diego, San Diego, California, United States of America
    PLoS ONE 6:e24946. 2011
    ....
  12. pmc Impact of the HIV epidemic on the incidence rates of anal cancer in the United States
    Meredith S Shiels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    J Natl Cancer Inst 104:1591-8. 2012
    ..Thus, the HIV epidemic may have influenced the increasing anal cancer trends in the United States. We estimated the impact of the HIV epidemic on trends in anal cancer incidence in the United States during 1980-2005...
  13. ncbi Perianal condylomas, anal squamous intraepithelial neoplasms and screening: a review of the literature
    Sheng Fei Oon
    Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
    J Med Screen 17:44-9. 2010
    ..This article explores the literature on ASILs and the growing problem of anal cancer in the community, along with the literature surrounding the current progress towards implementing a screening programme for ASIL in the future...
  14. pmc Understanding the burden of human papillomavirus-associated anal cancers in the US
    Djenaba A Joseph
    Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, Georgia 30341, USA
    Cancer 113:2892-900. 2008
    ..Anal cancer is an uncommon malignancy in the US; up to 93% of anal cancers are associated with human papillomavirus...
  15. ncbi The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology
    Teresa M Darragh
    Departments of Pathology and Obstetrics, Gynecology and Reproductive Science, University of California San Francisco Mt Zion Medical Center, 1600 Divisadero St, San Francisco, CA 94115, USA
    Arch Pathol Lab Med 136:1266-97. 2012
    ..The implemented recommendations will facilitate communication between pathologists and their clinical colleagues and improve accuracy of histologic diagnosis with the ultimate goal of providing optimal patient care...
  16. ncbi Anal cancer: an overview
    Hope E Uronis
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Oncologist 12:524-34. 2007
    ..We present a case of anal cancer followed by a general discussion of both risk factors and treatment...
  17. ncbi Intensity-modulated radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis
    Joseph M Pepek
    Department of Radiation Oncology, Duke University School of Medicine, Durham, NC 27710, USA
    Int J Radiat Oncol Biol Phys 78:1413-9. 2010
    ..Intensity-modulated radiation therapy (IMRT) has the potential to reduce toxicities associated with chemoradiotherapy in the treatment of anal cancer. This study reports the results of using IMRT in the treatment of anal cancer...
  18. pmc Prognostic biomarkers in squamous cell carcinoma of the anus: a systematic review
    T Lampejo
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, Praed Street, London, W2 1NY, UK
    Br J Cancer 103:1858-69. 2010
    ..Further insight into tumour characteristics and molecular biology may identify novel therapeutic targets. This systematic review examines current prognostic markers in SCC of the anus...
  19. pmc Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11
    Edgar Ben-Josef
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
    J Clin Oncol 28:5061-6. 2010
    ..To determine whether increased duration of radiation therapy (RT) and overall treatment (RX) time has a detrimental effect in anal cancer...
  20. pmc Estimation of the epidemiological burden of human papillomavirus-related cancers and non-malignant diseases in men in Europe: a review
    Susanne Hartwig
    Department of Epidemiology, Sanofi Pasteur MSD, Lyon, France
    BMC Cancer 12:30. 2012
    ..The objective of this review is to estimate the epidemiological burden of HPV-related cancers and non-malignant diseases in men in Europe...
  21. ncbi The epidemiology of anal human papillomavirus and related neoplasia
    Joel M Palefsky
    Division of Infectious Disease, Department of Medicine, University of California, Box 0126, Room M1203, San Francisco, CA 94143, USA
    Obstet Gynecol Clin North Am 36:187-200. 2009
    ..This article describes the epidemiology of anal HPV infection, anal intraepithelial neoplasia, and anal cancer among men and women, as well as current efforts to prevent anal cancers...
  22. ncbi Cancer in a population-based cohort of men and women in registered homosexual partnerships
    Morten Frisch
    Department of Epidemiology Research, Danish Epidemiology Science Center, Statens Serum Institut, Copenhagen, Denmark
    Am J Epidemiol 157:966-72. 2003
    ..8, 1.3). With anal squamous carcinoma and HIV/AIDS-associated cancers as notable exceptions in men, cancer incidence rates among homosexual persons in marriage-like partnerships are similar to those prevailing in society at large...
  23. ncbi HAART and progression to high-grade anal intraepithelial neoplasia in men who have sex with men and are infected with HIV
    Alexandra de Pokomandy
    Department of Medicine and Immunodeficiency Service, McGill University Health Center, Montreal, Quebec, Canada
    Clin Infect Dis 52:1174-81. 2011
    ..The goal of this study was to identify risk factors associated with high-grade AIN (AIN-2,3) in HIV-positive MSM, including the receipt of highly active antiretroviral therapy (HAART)...
  24. pmc Prognostic factors derived from a prospective database dictate clinical biology of anal cancer: the intergroup trial (RTOG 98-11)
    Jaffer A Ajani
    The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:4007-13. 2010
    ..A prognostic factor analysis for anal cancer from a prospective database has been published from only 1 study (N = 110). To confirm and uncover new prognostic factors, we analyzed the prospective database of intergroup RTOG 98-11...
  25. ncbi Growth factor receptor expression in anal squamous lesions: modifications associated with oncogenic human papillomavirus and human immunodeficiency virus
    Francine Walker
    Department of Pathology, Institut de la Santé et de la Recherche Médicale Unité773, Hopital Bichat Claude Bernard, 75018 Paris, France
    Hum Pathol 40:1517-27. 2009
    ..The finding that EGFR, c-Met, and VEGFR1 involved in carcinogenesis are well-represented and coexpressed in anal cancers, especially in HIV-positive population, suggests possible novel targeted treatments for anal diseases...
  26. ncbi Screening HIV-infected individuals for anal cancer precursor lesions: a systematic review
    Elizabeth Y Chiao
    Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center, TX, USA
    Clin Infect Dis 43:223-33. 2006
    ..This review identifies important areas for further study before routine anal Pap smear screening can be recommended...
  27. pmc Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas
    Robert J Myerson
    Department of Radiation Oncology, Washington University, St Louis, MO, USA
    Int J Radiat Oncol Biol Phys 74:824-30. 2009
    ..To develop a Radiation Therapy Oncology Group (RTOG) atlas of the elective clinical target volume (CTV) definitions to be used for planning pelvic intensity-modulated radiotherapy (IMRT) for anal and rectal cancers...
  28. ncbi The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual HIV-positive men
    S J Goldie
    Center for Risk Analysis, Department of Health Policy and Management, Harvard School of Public Health, Boston, Mass 02115 5924, USA
    JAMA 281:1822-9. 1999
    ..Homosexual and bisexual men infected with human immunodeficiency virus (HIV) are at increased risk for human papillomavirus-related anal neoplasia and anal squamous cell carcinoma (SCC)...
  29. ncbi Prevalence and risk factors for anal squamous intraepithelial lesions in women
    E A Holly
    Department of Epidemiology and Biostatistics, University of California, San Francisco 94143 1228, USA
    J Natl Cancer Inst 93:843-9. 2001
    ..Our aim was to determine the prevalence of human papillomavirus (HPV)-related abnormalities of the anal canal in women and to characterize risk factors for these lesions...
  30. ncbi Impact of overall treatment time on local control of anal cancer treated with radiochemotherapy
    R Graf
    Center of Radiation Medicine, Campus Virchow Clinic, Charite Medical School, Humboldt University, Berlin, Germany
    Oncology 65:14-22. 2003
    ....
  31. ncbi Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions
    Brooke E Hoots
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599 7400, USA
    Int J Cancer 124:2375-83. 2009
    ..If ongoing clinical trials show efficacy in preventing anal HPV infection and associated anal lesions, prophylactic HPV vaccines may play an important role for the primary prevention of these cancers in both genders...
  32. pmc The economic burden of noncervical human papillomavirus disease in the United States
    Delphine Hu
    Program in Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Obstet Gynecol 198:500.e1-7. 2008
    ....
  33. pmc A mouse model for human anal cancer
    Marie K Stelzer
    McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
    Cancer Prev Res (Phila) 3:1534-41. 2010
    ....
  34. ncbi Comparison of patient- and clinician-collected anal cytology samples to screen for human papillomavirus-associated anal intraepithelial neoplasia in men who have sex with men
    Peter V Chin-Hong
    University of California, San Francisco, Box 0654, 513 Parnassus Avenue, Room S 380, San Francisco, CA 94143 0654, USA
    Ann Intern Med 149:300-6. 2008
    ..Cytology screening can detect the anal cancer precursor, anal intraepithelial neoplasia (AIN). Little is known about self-collected samples for AIN screening, and few community-based AIN estimates exist...
  35. ncbi Sentinel node biopsy in squamous-cell carcinoma of the anal canal
    Paola De Nardi
    Department of Surgery, Scientific Institute San Raffaele Hospital, Milan, Italy
    Ann Surg Oncol 18:365-70. 2011
    ..In this study, we applied the sentinel node technique in patients with anal canal squamous-cell carcinoma to determine whether this provided more reliable staging of tumors...
  36. pmc IMRT for locally advanced anal cancer: clinical experience of the Montpellier Cancer Center
    Sabine Vieillot
    Département de cancérologie radiothérapie, CRLC Val d Aurelle Paul Lamarque, Montpellier, France
    Radiat Oncol 7:45. 2012
    ..To assess outcomes of patients with carcinoma of the anal canal (CAC) treated with intensity-modulated radiation therapy (IMRT)...
  37. ncbi Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy
    Catherine Diamond
    Department of Medicine, Epidemiology Division, University of California Irvine, Orange, California 92868, USA
    Sex Transm Dis 32:314-20. 2005
    ..We sought to determine if the introduction of highly active antiretroviral therapy (HAART) corresponded with changes in anal squamous cell cancer rates among men with AIDS...
  38. ncbi Human papillomavirus genotype distribution in anal cancer in France: the EDiTH V study
    Laurent Abramowitz
    APHP, Service de Gastroentérologie et proctologie, CHU Bichat, Paris, France
    Int J Cancer 129:433-9. 2011
    ..Our results indicate that anal cancer rarely occurs in the absence of HPV and emphasize the predominant role of HPV16. The potential benefit of HPV vaccine on the occurrence of anal cancer should be further evaluated...
  39. pmc Changing patterns of anal canal carcinoma in the United States
    Rebecca A Nelson
    City of Hope, Department of Surgery, Division of Surgical Oncology, 1500 E Duarte Rd, Duarte, CA 91010, USA
    J Clin Oncol 31:1569-75. 2013
    ..Persistent human papillomavirus infection is associated with squamous cell carcinoma of the anal canal (SCCA). With changing sexual behaviors, SCCA incidence and patient demographics may also have changed in recent years...
  40. pmc Anal intraepithelial neoplasia in a multisite study of HIV-infected and high-risk HIV-uninfected women
    Nancy A Hessol
    Department of Clinical Pharmacy, University of California, San Francisco, California 94122, USA
    AIDS 23:59-70. 2009
    ..To study anal intraepithelial neoplasia and its associations with anal and cervical human papillomavirus (HPV), cervical neoplasia, host immune status, and demographic and behavioral risk factors in women with and at risk for HIV infection...
  41. ncbi Using population-based cancer registry data to assess the burden of human papillomavirus-associated cancers in the United States: overview of methods
    Meg Watson
    Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Cancer 113:2841-54. 2008
    ....
  42. ncbi Malignant progression of anal intra-epithelial neoplasia
    Angus J M Watson
    Department of Surgery, Colorectal Unit, Christchurch Hospital, New Zealand
    ANZ J Surg 76:715-7. 2006
    ..This study reviews our experience with AIN, reviewing the incidence and risk factors for development of invasive malignancy and the outcome of present management strategies...
  43. ncbi Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastro
    H Bartelink
    Department of Radiotherapy, The Netherlands Cancer Institute Antoni van Leeuwenhoek Huis, Amsterdam, The Netherlands
    J Clin Oncol 15:2040-9. 1997
    ....
  44. ncbi Organ-sparing Intensity-modulated radiotherapy for anal cancer using the ACTII schedule: a comparison of conventional and intensity-modulated radiotherapy plans
    C J Brooks
    Department of Medical Physics, Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK
    Clin Oncol (R Coll Radiol) 25:155-61. 2013
    ..4 Gy in 1.8 Gy/fraction: 17 fractions for phase 1 and 11 fractions for phase 2...
  45. ncbi Squamous cell carcinoma of the anal canal: a review of the aetiology, presentation, staging, prognosis and methods available for treatment
    Ursula M Szmulowicz
    Department of Colon and Rectal Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Sex Health 9:593-609. 2012
    ..The introduction of human papillomavirus vaccines presents the exciting potential for the eradication of the disease...
  46. ncbi Induction chemotherapy and dose intensification of the radiation boost in locally advanced anal canal carcinoma: final analysis of the randomized UNICANCER ACCORD 03 trial
    Didier Peiffert
    EA 4360Centre, Alexis Vautrin and Nancy University, Vandoeuvre les Nancy, France
    J Clin Oncol 30:1941-8. 2012
    ..Our trial was designed to determine whether dose escalation of the radiation boost or two cycles of ICT before concomitant RCT lead to an improvement in colostomy-free survival (CFS)...
  47. ncbi Australasian Gastrointestinal Trials Group (AGITG) contouring atlas and planning guidelines for intensity-modulated radiotherapy in anal cancer
    Michael Ng
    Radiation Oncology Victoria, Victoria, Australia
    Int J Radiat Oncol Biol Phys 83:1455-62. 2012
    ..To develop a high-resolution target volume atlas with intensity-modulated radiotherapy (IMRT) planning guidelines for the conformal treatment of anal cancer...
  48. ncbi TGF-beta receptor I conditional knockout mice develop spontaneous squamous cell carcinoma
    Yasuyuki Honjo
    Functional Genomics Section, Laboratory of Cellular and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cell Cycle 6:1360-6. 2007
    ..This is the first demonstration that loss of TbetaRI can lead to spontaneous tumor formation. These mice can serve as a unique mouse model of SCC to evaluate the tumorigenicity and effect of anti-cancer therapeutics...
  49. pmc Rapamycin inhibits anal carcinogenesis in two preclinical animal models
    Marie K Stelzer
    McArdle Laboratory for Cancer Research, Madison, WI 53705, USA
    Cancer Prev Res (Phila) 3:1542-51. 2010
    ..As has been seen in other cancers, rapamycin treatment led to an activation of the MAPK pathway. These results provide us cause to pursue further the evaluation of rapamycin as a therapeutic agent in the control of anal cancer...
  50. ncbi Malignant transformation of high-grade anal intraepithelial neoplasia
    J H Scholefield
    Department of Surgery, Queens Medical Centre, Nottingham, UK
    Br J Surg 92:1133-6. 2005
    ..This makes management problematic as treatment options to eradicate the condition carry morbidity. The authors report their 10-year experience with conservative management of this condition, highlighting the lessons learnt...
  51. ncbi Distribution of HPV genotypes in Slovenian patients with anal carcinoma: preliminary results
    Kristina Fujs Komlos
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia
    Acta Dermatovenerol Alp Pannonica Adriat 20:141-3. 2011
    ..Prophylactic HPV vaccination with currently available vaccines could potentially prevent the great majority of anal cancers in Slovenia...
  52. ncbi Trends in incidence of anal cancer and high-grade anal intraepithelial neoplasia in Denmark, 1978-2008
    Ann Nielsen
    Department of Viruses, Hormones and Cancer, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 130:1168-73. 2012
    ..Our findings indicate that vaccines against HPV might play an important role in the prevention of anal cancer and its precursor lesions...
  53. ncbi An update on tumors of the anal canal
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
    Arch Pathol Lab Med 134:1601-11. 2010
    ..The anal canal possesses complex anatomy and histology and gives rise to a variety of tumor types. Challenging issues remain with regard to both the pathologic diagnosis and the clinical management of these tumors...
  54. pmc Human papillomavirus genotype distribution in Czech women and men with diseases etiologically linked to HPV
    Ruth Tachezy
    Department of Experimental Virology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    PLoS ONE 6:e21913. 2011
    ..The HPV genotype distribution varies across different geographical regions. Therefore, we investigated the type-specific HPV prevalence in Czech women and men with anogenital diseases...
  55. ncbi Incidence of anal cancer in California: increased incidence among men in San Francisco, 1973-1999
    Rosemary D Cress
    California Cancer Registry, Sacramento, CA, USA
    Prev Med 36:555-60. 2003
    ..Incidence of anal cancer has increased in the United States during the past 30 years. This report describes the incidence of this rare cancer in the diverse California population...
  56. ncbi Surgical management of primary anorectal melanoma
    P Pessaux
    Department of Surgery, Comprehensive Cancer Centre, Institut Gustave Roussy, Villejuif, France
    Br J Surg 91:1183-7. 2004
    ..This aim of this study was to analyse outcome after surgery for primary anorectal melanoma and to determine factors predictive of survival...
  57. ncbi Implantation of rectal cancer in an anal fistula: report of a case
    Satoshi Ishiyama
    Deparment of Surgery, Jikei University School of Medicine, Minato ku, Tokyo 105 8461, Japan
    Surg Today 36:747-9. 2006
    ..Although the recurrence of rectal cancer by mucosal implantation is not uncommon, the coincidental implantation of rectal cancer in an anal fistula is extremely rare...
  58. ncbi Results of definitive irradiation in a series of 305 epidermoid carcinomas of the anal canal
    Elisabeth Deniaud-Alexandre
    Department of Radiation Oncology, Tenon Hospital A P H P, Paris, France
    Int J Radiat Oncol Biol Phys 56:1259-73. 2003
    ..To evaluate our data concerning the prognostic factors for locoregional control, survival, late complications, and sphincter conservation in a series of epidermoid cancers of the anal canal without clinical evidence of metastasis...
  59. ncbi Human papillomavirus genotypes in anal intraepithelial neoplasia and anal carcinoma as detected in tissue biopsies
    Anna K Wong
    Department of Pathology and Laboratory Medicine, George Burns and Gracie Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Mod Pathol 23:144-50. 2010
    ..In addition, a subset of these that were associated with type 16 or 18 showed progression, whereas those associated with non-16/18 subtypes regressed, thereby raising the possibility of conservative management for these lesions...
  60. ncbi Biology of HPV in HIV infection
    J Palefsky
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0126, USA
    Adv Dent Res 19:99-105. 2006
    ....
  61. ncbi Human papillomavirus anogenital disease in HIV-infected individuals
    Peter V Chin-Hong
    Department of Medicine, University of California, San Francisco 94143 0654, USA
    Dermatol Ther 18:67-76. 2005
    ..Prophylactic and therapeutic HPV vaccines are promising as future interventions for disease control in at-risk populations such as HIV-infected women and men...
  62. ncbi High resolution anoscopy findings for men who have sex with men: inaccuracy of anal cytology as a predictor of histologic high-grade anal intraepithelial neoplasia and the impact of HIV serostatus
    Lori A Panther
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 38:1490-2. 2004
    ..The presence of any abnormal anal cytological finding indicates a potential for high-grade dysplasia on histological examination of MSM...
  63. pmc Risk of anal cancer in HIV-infected and HIV-uninfected individuals in North America
    Michael J Silverberg
    Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA
    Clin Infect Dis 54:1026-34. 2012
    ..There are also conflicting data regarding calendar trends...
  64. ncbi Anal cancer: the end of the road for neoadjuvant chemoradiotherapy?
    Rob Glynne-Jones
    Mount Vernon Cancer Centre, Northwood, Middlesex, United Kingdom
    J Clin Oncol 26:3669-71. 2008
  65. ncbi Anal carcinoma in human immunodeficiency virus-positive men: results of a prospective study from Germany
    A Kreuter
    Department of Dermatology, Ruhr University Bochum, Gudrunstrasse 56, D 44791 Bochum, Germany
    Br J Dermatol 162:1269-77. 2010
    ..There is a paucity of data published on the progression of high-grade AIN to invasive cancer as well as on clinical and virological characteristics comparing anal margin and anal canal carcinoma...
  66. ncbi Beyond cervical cancer: burden of other HPV-related cancers among men and women
    Anil K Chaturvedi
    Division of Cancer Epidemiology and Genetics, Infections and Immunoepidemiology Branch, National Cancer Institute, Rockville, Maryland 20852, USA
    J Adolesc Health 46:S20-6. 2010
    ....
  67. pmc Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08
    Andre Konski
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 72:114-8. 2008
    ..Long-term efficacy and late toxicity reporting are the specific aims of this study...
  68. ncbi Management of anal cancer in 2010. Part 1: Overview, screening, and diagnosis
    Ali Abbas
    School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Oncology (Williston Park) 24:364-9. 2010
    ..1% for localized anal cancer, 60.7% for regional disease, and 29.4% for metastatic disease. Part 2 of this two-part review will address the treatment of anal cancer, highlighting studies of chemoradiation...
  69. ncbi Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases
    M Miettinen
    Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Am J Surg Pathol 25:1121-33. 2001
    ..Intramural LMs are exceptional, and true LMSs are rare, and similar to colonic ones, often present as intraluminal polypoid masses that appear to have a better prognosis than GISTs with similar mitotic rates...
  70. ncbi Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer
    Janet R Daling
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer 101:270-80. 2004
    ..The incidence of anal cancer has increased among both men (160%) and women (78%) from 1973 to 2000 in the U.S. The authors conducted a population-based case-control study of anal cancer to examine factors that may account for this increase...
  71. ncbi Organ sparing by conformal avoidance intensity-modulated radiation therapy for anal cancer: dosimetric evaluation of coverage of pelvis and inguinal/femoral nodes
    Yi Jen Chen
    Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA 91010 3000, USA
    Int J Radiat Oncol Biol Phys 63:274-81. 2005
    ....
  72. pmc Plan comparison of volumetric-modulated arc therapy (RapidArc) and conventional intensity-modulated radiation therapy (IMRT) in anal canal cancer
    Sabine Vieillot
    Département de Cancérologie Radiothérapie et de Radiophysique, CRLC Val d Aurelle Paul Lamarque, Montpellier, France
    Radiat Oncol 5:92. 2010
    ..To compare volumetric-modulated arc therapy (RapidArc) plans with conventional intensity-modulated radiation therapy (IMRT) plans in anal canal cancers...
  73. ncbi Age-related prevalence of anal cancer precursors in homosexual men: the EXPLORE study
    Peter V Chin-Hong
    Department of Medicine, University of California San Francisco, CA 94143 0654, USA
    J Natl Cancer Inst 97:896-905. 2005
    ..The prevalence of cervical cancer precursor lesions peaks at around 30 years of age. The age-related prevalence of ASILs in HIV-negative MSM is unknown...
  74. ncbi High prevalence of anal human papillomavirus infection and anal cancer precursors among HIV-infected persons in the absence of anal intercourse
    Christophe Piketty
    INSERM U 430 and Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Ann Intern Med 138:453-9. 2003
    ..Anal HPV infection and anal SIL are common in HIV-positive men who have sex with men; receptive anal intercourse is presumed to be the mode of acquisition of HPV...
  75. ncbi Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Mail Stop 426, Houston, Texas 77030, USA
    JAMA 299:1914-21. 2008
    ..Chemoradiation as definitive therapy is the preferred primary therapy for patients with anal canal carcinoma; however, the 5-year disease-free survival rate from concurrent fluorouracil/mitomycin and radiation is only approximately 65%...
  76. ncbi Squamous cell carcinoma of the anal canal
    Dennis L Rousseau
    Division of Surgical Oncology, Department of Surgery, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
    Surg Oncol 14:121-32. 2005
    ..The surgeon plays a key role in the diagnosis and follow-up of this disease. Surgical salvage with APR for disease persistence or recurrence in carefully selected patients can result in reasonable 5-year survivals...
  77. pmc Estimating the accuracy of anal cytology in the presence of an imperfect reference standard
    William C Mathews
    Department of Medicine, University of California San Diego, San Diego, California, United States of America AI 36214
    PLoS ONE 5:e12284. 2010
    ..The study aim is to estimate sensitivity and specificity of anal cytology for histologic HSIL in analyses adjusted for the imperfect biopsy reference standard...
  78. ncbi Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, Unit 426, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA
    Dig Dis Sci 55:1098-105. 2010
    ..Upon further expansion and validation, these results may provide a biomarker-based understanding of heterogeneous clinical biology of patients with anal carcinoma...
  79. ncbi Anal cancer and cervical cancer screening: key differences
    Teresa M Darragh
    Department of Pathology, University of California, San Francisco, CA, USA
    Cancer Cytopathol 119:5-19. 2011
    ..This article provides an overview of anal cancer screening while highlighting its differences from cervical cancer screening and the remaining obstacles and controversies to implementation of a successful anal cancer screening program...
  80. ncbi Performance characteristics of anal cytology and human papillomavirus testing in patients with high-resolution anoscopy-guided biopsy of high-grade anal intraepithelial neoplasia
    J Michael Berry
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Dis Colon Rectum 52:239-47. 2009
    ..High-resolution anoscopy with biopsy was used as the standard for detecting high-grade anal neoplasia and was compared to detection of high-grade anal neoplasia by anal cytology, human papillomavirus testing, or the combination...
  81. ncbi Chemoradiotherapy in patients with anal cancer: impact of length of unplanned treatment interruption on outcome
    Andreas Meyer
    Department of Radiation Oncology, Medical School Hannover, Hannover, Germany
    Acta Oncol 45:728-35. 2006
    ..762), respectively. Chemoradiotherapy with short individualised treatment interruptions seems to be feasible with acceptable acute or late toxicities. Treatment is highly effective in terms of local control and colostomy-free survival...
  82. ncbi Oncologic outcomes of salvage surgery for epidermoid carcinoma of the anus initially managed with combined modality therapy
    Robert P Akbari
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Dis Colon Rectum 47:1136-44. 2004
    ..Primary chemoradiation failure for epidermoid carcinoma of the anus is treated by surgical resection. This study evaluates the outcome of salvage surgery at one institution...
  83. ncbi Anal carcinoma: incidence and effect of cumulative infections
    Iradj Sobhani
    FAMA de Colo Proctologie et INSERM U 410, Hopital Bichat Claude Bernard, Paris, France
    AIDS 18:1561-9. 2004
    ..Human papilloma virus (HPV) causes anal condyloma that is a risk factor for anal carcinoma. The incidence and mechanism of invasive anal carcinoma in patients with anal condyloma are prospectively determined...
  84. ncbi Comparison of positron emission tomography scanning and sentinel node biopsy in the detection of inguinal node metastases in patients with anal cancer
    Massimiliano Mistrangelo
    Department of Surgery, University of Turin, Turin, Italy
    Int J Radiat Oncol Biol Phys 77:73-8. 2010
    ..We compared this technique vs. dedicated 18F-fluorodeoxyglucose positron emission tomography (PET) to determine which was the better tool for staging inguinal lymph nodes...
  85. ncbi Anal HPV genotypes and related displasic lesions in Italian and foreign born high-risk males
    Giovanna Orlando
    US MTS, II Division Infectious Diseases, Department of Infectious Diseases, STD Unit, L Sacco University Hospital, Via GB Grassi, 74 20157 Milan, Italy
    Vaccine 27:A24-9. 2009
    ....
  86. ncbi Anus-preservation treatment for anal cancer: retrospective analysis at a single institution
    Yi Wei Chen
    Cancer Center, Taipei Veterans General Hospital and Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    J Surg Oncol 96:374-80. 2007
    ..To evaluate anus-preservation treatment for anal cancer...
  87. pmc Limited value of staging squamous cell carcinoma of the anal margin and canal using the sentinel lymph node procedure: a prospective study with long-term follow-up
    Johannes S de Jong
    Department of Surgery, Division of Surgical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Ann Surg Oncol 17:2656-62. 2010
    ..This study reports the feasibility of the sentinel lymph node biopsy (SLNB) in patients with anal cancer and whether this improves the selection for inguinal radiotherapy...
  88. pmc Combined analysis of cell growth and apoptosis-regulating proteins in HPVs associated anogenital tumors
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyou ku, Tokyo, 113 8603, Japan
    BMC Cancer 10:118. 2010
    ..Here we evaluated molecules that are relevant to cellular proliferation and regulation of apoptosis in HPV associated anogenital tumors...
  89. ncbi Twenty-year experience in the management of squamous cell anal canal carcinoma with interstitial brachytherapy
    José Luis López Guerra
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, 77030 Houston, TX, USA
    Clin Transl Oncol 13:472-9. 2011
    ..The aim of this study was to retrospectively evaluate clinical characteristics, local control, acute and late toxicity, and prognostic factors of patients with anal canal carcinoma treated with brachytherapy...
  90. ncbi Treatment of squamous cell anal canal carcinoma (SCACC) with pulsed dose rate brachytherapy: a retrospective study
    Antoine Bruna
    Brachytherapy Department, Centre Alexis Vautrin, Vandoeuvre les Nancy, France
    Radiother Oncol 79:75-9. 2006
    ..To evaluate the results of pulsed dose rate brachytherapy (PDR) in SCACC...
  91. ncbi Synchronous carcinoma of the sigmoid colon and a perianal fistula
    Andrew P Zbar
    Dis Colon Rectum 47:544-5; author reply 545. 2004
  92. ncbi The impact of gap duration on local control in anal canal carcinoma treated by split-course radiotherapy and concomitant chemotherapy
    D C Weber
    Radiation Oncology Department of the University Hospital, Geneva, Switzerland
    Int J Radiat Oncol Biol Phys 50:675-80. 2001
    ..The present analysis suggests that shortening the gap contributes to optimizing LRC. Gaps longer than 5 weeks correlated with poorer LRC, with especially unsatisfactory results observed in younger patients...
  93. ncbi FHIT oncosuppressor gene expression profile in human anal cancers
    C Zucchini
    Molecular Genetics Research Center Fondazione CARISBO, Department of Histology, Embryology and Applied Biology, University of Bologna, Bologna, Italy
    Int J Biol Markers 22:39-42. 2007
    ..The absence or poor expression of the Fhit protein in anal cancers suggests a role for this tumor suppressor gene product, as a risk factor, in the onset of this human cancer, as reported before for other human gastrointestinal tumors...
  94. ncbi Performance of p16INK4a immunocytochemistry as a marker of anal squamous intraepithelial lesions
    Ivan Tramujas da Costa e Silva
    Postgraduation Program of Tropical Medicine Foundation of Amazonas University of the State of Amazonas, Manaus, Brazil, Department of Surgery, School of Medicine, Federal University of Amazonas, Manaus, Brazil
    Cancer Cytopathol 119:167-76. 2011
    ..This study examined measures of diagnostic validity of ICCp16 in HIV-positive patients treated at the Tropical Medicine Foundation of Amazonas in the coloproctology outpatient clinic...
  95. ncbi A population-based analysis of temporal trends in the incidence of squamous anal canal cancer in relation to the HIV epidemic
    Elizabeth Y Chiao
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Acquir Immune Defic Syndr 40:451-5. 2005
    ..The incidence of SCCA has particularly increased among men and those between 30 and 54 years of age since the introduction of HAART...
  96. ncbi Prognostic factors in anal carcinoma
    Claus Fenger
    Department of Pathology, Odense University Hospital, Denmark
    Pathology 34:573-8. 2002
    ..It is concluded that future research should concentrate on larger, probably multicentre series using standardised methods and criteria for evaluation...
  97. ncbi Differential expression of anti-apoptotic protein Bcl-2 in keratinizing versus non-keratinizing squamous cell carcinoma of the anus
    Abdelkarim S Allal
    Division of Radiation Oncology, University Hospital Geneva, Rue Micheli du Crest 24, 1211 Geneva, Switzerland
    Int J Colorectal Dis 20:161-4. 2005
    ..The present study was undertaken to compare the expression of apoptosis-regulating proteins Bcl-2 and p53 in K versus NK SCCA...
  98. ncbi Metastatic anal cancer: the search for cure
    Bernard J Cummings
    Onkologie 29:5-6. 2006
  99. ncbi Ano-genital neoplasia in renal transplant patients
    F H Sillman
    Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Ann Transplant 2:59-66. 1997
    ..Next best is detecting HPV/intraepithelial neoplasia early with frequent inspection, cytology and liberal biopsies; and then removing any condylomas or intraepithelial neoplasia that develop...
  100. ncbi Anal fibroadenoma: report of a common tumor type in an unusual location
    William W L Choi
    South Med J 100:914-5. 2007
  101. ncbi On the etiology of anal squamous carcinoma
    Morten Frisch
    Statens Serum Institut, Department of Epidemiological Research, Artillerivej 3, DK 2300 København S
    Dan Med Bull 49:194-209. 2002
    ..It this optimism is justified, the future may bring drastic reductions in the incidence of HPV-associated morbidities, including SC...

Research Grants24

  1. Strategies Against HPV Related Genital Diseases in Women
    Bradley Monk; Fiscal Year: 2006
    ..It is expected that Dr. Monk will have obtained extramural funding for both his laboratory and clinical studies by the end of the period of support requested. ..
  2. Anogenital HPV Infection in a Population-Based Sample of Puerto Rican Women
    Ana Patricia Ortiz; Fiscal Year: 2012
    ....
  3. The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
    Elizabeth Chiao; Fiscal Year: 2010
    ....
  4. Anal HPV Infection and ASIL in HIV+ and HIV- Women
    Joel Palefsky; Fiscal Year: 2006
    ..Knowledge of genes involved in ASIL pathogenesis may provide new approaches to therapy of both anal and cervical HSIL as well as markers for disease progression. ..
  5. NATURAL HISTORY OF ANAL NEOPLASIA IN HIV INFECTED MEN
    Joel Palefsky; Fiscal Year: 2002
    ....
  6. Anal Dysplasia in HIV+ and HIV- men
    Timothy Wilkin; Fiscal Year: 2006
    ..This study will help provide important new information on which groups of HIV+ men may benefit from screening and how HAART may modify this risk. ..
  7. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2004
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  8. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..S. and specifically assess how best to modify cytology-based screening, utilize HPV diagnostics, and tailor aoDrooriate follow-uo strategies for adolescents and vouna women diaanosed with CIN 2 ..
  9. HIV-1 Proviral DNA and Monocyte Phenotype in Relation to Neurocognitive Function
    Bruce T Shiramizu; Fiscal Year: 2010
    ..This resource-rich team is well-positioned to conduct this investigation into the pathogenesis of HAD. ..
  10. Molecular Epidemiology of Endometrial Cancer
    Chu Chen; Fiscal Year: 2007
    ..Efforts will also be devoted to generating risk indices through statistical modeling that integrate potential effects of genetic variants in the estrogen metabolism pathway and/or DNA repair pathways. ..
  11. ORAL CANCER: MOLECULAR PROFILES & CLINICAL OUTCOMES
    Chu Chen; Fiscal Year: 2010
    ..HPV plays an important etiologic role in some oropharyngeal cancers, we plan to determine and incorporate HPV genotypes in the analyses and interpretation of the study findings. ..
  12. Real-time Minimal Residual Disease assay of Pediatric B-Cell Non-Hodgkin Lymphoma
    Bruce Shiramizu; Fiscal Year: 2007
    ..The assay developed by this exploratory proposal could be incorporated into pediatric B-cell NHL studies to assess MRD on therapy or to assess the efficacy of innovative therapies. [unreadable] [unreadable] [unreadable]..
  13. CALCIUM CHANNEL BLOCKERS IN BREAST CANCER ETIOLOGY
    Janet Daling; Fiscal Year: 2001
    ..cimetidine, anti-depressants, lipid lowering drugs) frequently used by women in this age group. ..
  14. Activated Immune Parameters Associated with HIV & Aging
    Bruce Shiramizu; Fiscal Year: 2004
    ....
  15. Treatment and Outcome of AIDS-related Lymphoma
    Catherine Diamond; Fiscal Year: 2006
    ..Lastly, we will determine how the use of HAART influences the IPI and develop a prognostic model that incorporates HIV-related factors, tumor characteristics, HAART, and chemotherapy. ..
  16. PET IMAGING IN MULTIMODALITY MANAGEMENT OF RECTAL CANCER
    Jose Guillem; Fiscal Year: 2001
    ..abstract_text> ..
  17. HRT USE AND RISK OF LOBULAR AND DUCTAL BREAST CANCER
    Janet Daling; Fiscal Year: 2004
    ..of CHRT associated with alteration in the histologic characteristics, tumor cell proliferation, or expression of steroid hormone receptors, oncogenes, and cell cycle and cell death regulator proteins of lobular and ductal breast cancers? ..
  18. MOLECULAR EPIDEMIOLOGY OF LUNG CANCER
    Chu Chen; Fiscal Year: 2010
    ..g. Rosaceae fruits and Cruciferae vegetables), and food-derived nutrients (e.g. carotenoids, vitamin C, and vitamin E). ..
  19. Clinical & Cost Effectiveness of HPV Vaccination in the US
    Sue Goldie; Fiscal Year: 2009
    ....
  20. BREAST CANCER AND GENE POLYMORPHISMS IN CHINESE WOMEN
    Chu Chen; Fiscal Year: 2003
    ..Our ultimate goal is to provide information to identify women at high risk of breast cancer, and to aid in the formulation of prevention strategies for these women. ..
  21. Human papillomavirus as a risk factor for HIV infection
    PETER CHIN HONG; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  22. Effect of Oxidant Load on HPV Persistence and CIN (SIL)
    Anna Giuliano; Fiscal Year: 2008
    ..abstract_text> ..
  23. Cidofovir for Perianal Dysplasia in HIV Patients
    Elizabeth Stier; Fiscal Year: 2006
    ..Novel treatments, such as topical cidofovir, may prevent pre-cancerous lesions from developing into cancer in HIV-infected patients. ..