gastritis

Summary

Summary: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.

Top Publications

  1. ncbi Helicobacter pylori infection and the development of gastric cancer
    N Uemura
    Department of Gastroenterology, Kure Kyosai Hospital, Kure City, Japan
    N Engl J Med 345:784-9. 2001
  2. doi Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Gastroenterology 135:91-9. 2008
  3. doi MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic Gastritis and Colitis
    Mathias Oertli
    Institute of Molecular Cancer Research, University of Zurich, 8057 Zurich, Switzerland
    J Immunol 187:3578-86. 2011
  4. ncbi Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    E M El-Omar
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Nature 404:398-402. 2000
  5. pmc Interplay between the gastric bacterial microbiota and Candida albicans during postantibiotic recolonization and gastritis
    Katie L Mason
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Infect Immun 80:150-8. 2012
  6. ncbi Long-term follow up of patients with multiple gastric carcinoids associated with type A gastritis
    Osamu Hosokawa
    Department of Surgery, Fukui Prefectural Hospital, 2 8 1 Yotsui, Fukui 910 8526, Japan
    Gastric Cancer 8:42-6. 2005
  7. ncbi Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-gamma, gene-deficient mice
    L E Smythies
    Department of Medicine, Pathology, and Comparative Medicine, University of Alabama, Birmingham, AL 35294, USA
    J Immunol 165:1022-9. 2000
  8. ncbi Helicobacter pylori and gastrointestinal tract adenocarcinomas
    Richard M Peek
    Division of Gastroenterology, Vanderbilt University School of Medicine, Medical Center North, Nashville, Tennessee 37232 2279, USA
    Nat Rev Cancer 2:28-37. 2002
  9. pmc Long term follow up of patients treated for Helicobacter pylori infection
    R Mera
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido St, New Orleans, LA 70112, USA
    Gut 54:1536-40. 2005
  10. ncbi The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice
    K A Eaton
    Department of Veterinary Biosciences, Ohio State University, Columbus, OH 43210, USA
    J Immunol 166:7456-61. 2001

Detail Information

Publications272 found, 100 shown here

  1. ncbi Helicobacter pylori infection and the development of gastric cancer
    N Uemura
    Department of Gastroenterology, Kure Kyosai Hospital, Kure City, Japan
    N Engl J Med 345:784-9. 2001
    ..Although many studies have found an association between Helicobacter pylori infection and the development of gastric cancer, many aspects of this relation remain uncertain...
  2. doi Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Gastroenterology 135:91-9. 2008
    ..We assessed the association of new and established cagA and vacA polymorphisms with disease...
  3. doi MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic Gastritis and Colitis
    Mathias Oertli
    Institute of Molecular Cancer Research, University of Zurich, 8057 Zurich, Switzerland
    J Immunol 187:3578-86. 2011
    ..pylori-induced chronic gastritis and associated gastric preneoplastic pathology...
  4. ncbi Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    E M El-Omar
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Nature 404:398-402. 2000
    ..not clear, but the gastric physiological response is influenced by the severity and anatomical distribution of gastritis induced by H. pylori...
  5. pmc Interplay between the gastric bacterial microbiota and Candida albicans during postantibiotic recolonization and gastritis
    Katie L Mason
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Infect Immun 80:150-8. 2012
    ..Disturbance of the gastric bacterial community by cefoperazone alone was not sufficient to cause gastritis, C. albicans colonization was also needed...
  6. ncbi Long-term follow up of patients with multiple gastric carcinoids associated with type A gastritis
    Osamu Hosokawa
    Department of Surgery, Fukui Prefectural Hospital, 2 8 1 Yotsui, Fukui 910 8526, Japan
    Gastric Cancer 8:42-6. 2005
    Little is known about the natural course of multiple gastric carcinoids associated with type A gastritis. Between 1993 and 2003, we enrolled eight patients, diagnosed as having multiple gastric carcinoids associated with type A gastritis,..
  7. ncbi Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-gamma, gene-deficient mice
    L E Smythies
    Department of Medicine, Pathology, and Comparative Medicine, University of Alabama, Birmingham, AL 35294, USA
    J Immunol 165:1022-9. 2000
    To elucidate the pathogenesis of Helicobacter pylori-associated gastritis, we studied immune responses of C57BL/6J wild-type (WT), SCID, and gene deficient (IFN-gamma-/- and IL-4-/-) mice following infection with a pathogenic isolate of ..
  8. ncbi Helicobacter pylori and gastrointestinal tract adenocarcinomas
    Richard M Peek
    Division of Gastroenterology, Vanderbilt University School of Medicine, Medical Center North, Nashville, Tennessee 37232 2279, USA
    Nat Rev Cancer 2:28-37. 2002
    ....
  9. pmc Long term follow up of patients treated for Helicobacter pylori infection
    R Mera
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido St, New Orleans, LA 70112, USA
    Gut 54:1536-40. 2005
    ..Understanding long term effects resulting from the cure of this infection is needed to design cancer prevention strategies...
  10. ncbi The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice
    K A Eaton
    Department of Veterinary Biosciences, Ohio State University, Columbus, OH 43210, USA
    J Immunol 166:7456-61. 2001
    b>Gastritis due to Helicobacter pylori in mice and humans is considered a Th1-mediated disease, but the specific cell subsets and cytokines involved are still not well understood...
  11. ncbi Importance of Helicobacter pylori oipA in clinical presentation, gastric inflammation, and mucosal interleukin 8 production
    Yoshio Yamaoka
    Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 123:414-24. 2002
    ..The aim was to determine which H. pylori virulence factor(s) was the most important predictor of severity of gastric inflammation or clinical outcome...
  12. ncbi Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis
    Tomomitsu Tahara
    Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan
    Gastrointest Endosc 70:246-53. 2009
    ..Magnifying narrow-band imaging (NBI) endoscopy clearly visualizes superficial gastric mucosal patterns and capillary patterns...
  13. ncbi Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis
    Marco Centanni
    Endocrinology Unit, Department of Experimental Medicine and Pathology, University La Sapienza, Polo Pontino, Latina, Italy
    N Engl J Med 354:1787-95. 2006
    ..We determined whether there is an increased need for thyroxine in patients with euthyroid multinodular goiter and impaired secretion of gastric acid...
  14. doi The role of interleukin-17 in the Helicobacter pylori induced infection and immunity
    Shahjahan Kabir
    Academic Research and Information Management, Uppsala, Sweden
    Helicobacter 16:1-8. 2011
    ....
  15. pmc Detection of p53 mutations in precancerous gastric tissue
    C Morgan
    Human Molecular Pathology Group, Swansea Clinical School, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
    Br J Cancer 89:1314-9. 2003
    Intestinal-type gastric cancer is preceded by gastritis and intestinal metaplasia. There is uncertainty regarding the stage at which genetic alterations in the p53 gene occur...
  16. ncbi Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan
    Ayumu Taguchi
    Division of Gastroenterology, Department of Therapeutic Medicine, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya, Aichi, 466 8550 Japan
    Cancer Epidemiol Biomarkers Prev 14:2487-93. 2005
    ..We aimed to clarify the relationship of interleukin (IL)-8 polymorphism with the risk of atrophic gastritis and gastric cancer...
  17. ncbi The updated Sydney system: classification and grading of gastritis as the basis of diagnosis and treatment
    M Stolte
    Department of Pathology, Klinikum Bayreuth, Preuschwitzerstrasse 101, 95445 Bayreuth, Germany
    Can J Gastroenterol 15:591-8. 2001
    In recent years, the importance of the histological diagnosis of gastritis on the basis of routinely obtained antral and corpus biopsies has increased enormously, which is owed not least of all to the discovery of Helicobacter pylori...
  18. pmc CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice
    Mohammad S Alam
    Digestive Health Center, Division of Gastroenterology and Hepatology, Department of Medicine, University of Virginia, Charlottesville, VA 22908 0708, USA
    J Infect Dis 199:494-504. 2009
    ..We investigated the expression of CD39 and CD73 on human T helper (Th) cells and the role of CD73 in regulating Helicobacter felis-induced gastritis and colonization.
  19. pmc Accelerated progression of gastritis to dysplasia in the pyloric antrum of TFF2 -/- C57BL6 x Sv129 Helicobacter pylori-infected mice
    James G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Am J Pathol 171:1520-8. 2007
    ..pylori-infected mice at 19 months pi. These data support a protective role for TFF2 in part by modulating levels of gastric interferon-gamma in the development of H. pylori-associated premalignancy of the distal stomach...
  20. pmc Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countries
    Y Yamaoka
    Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    J Clin Microbiol 37:2274-9. 1999
    ..obtained from patients with different clinical presentations (peptic ulcer, gastric cancer, and atrophic gastritis). The H. pylori isolates examined included 107 strains from Bogota, Colombia, 70 from Houston, Tex...
  21. ncbi Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer
    Sabine Krueger
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    J Pathol 207:32-42. 2005
    ..Patients with H. pylori gastritis showed significantly higher cathepsin X mRNA (2.5-fold) and protein (1.6-fold) expression than H...
  22. doi Helicobacter pylori gastritis in children is associated with a regulatory T-cell response
    Paul R Harris
    Department of Pediatrics, Pontificia Universidad Católica de Chile and Hospital Dr Sótero del Río, Santiago, Chile
    Gastroenterology 134:491-9. 2008
    ....
  23. ncbi Profile of aberrant CpG island methylation along the multistep pathway of gastric carcinogenesis
    Gyeong Hoon Kang
    Department of Pathology, Seoul National University College of Medicine and Cancer Research Institute, Seoul, Korea
    Lab Invest 83:635-41. 2003
    ..collection of GC (n = 80), gastric adenoma (GA) (n = 79), intestinal metaplasia (IM) (n = 57), and chronic gastritis (CG) (n = 74)...
  24. ncbi Effects of interleukin-10 gene polymorphism on the development of gastric cancer and peptic ulcer in Japanese subjects
    Mitsushige Sugimoto
    First Department of Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
    J Gastroenterol Hepatol 22:1443-9. 2007
    ..The aim of the present study was to clarify the association between the IL-10 polymorphism, one of the representative anti-inflammatory cytokines, and susceptibility to gastric cancer and peptic ulcer in Japan...
  25. pmc African, Asian or Indian enigma, the East Asian Helicobacter pylori: facts or medical myths
    David Y Graham
    Department of Medicine, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    J Dig Dis 10:77-84. 2009
    ..and Indian enigmas relate to gastric cancer and peptic ulcers, respectively, and when one takes the patterns of gastritis in the different regions, these enigmas disappear...
  26. ncbi Prevalence of silent gastric ulcer, erosions or severe acute gastritis in patients with type 2 diabetes mellitus--a cross-sectional study
    Michael W J Boehme
    Wilhelm Fresenius Klinik Dr Horst Schmidt Kliniken, Department of Internal Medicine, Wiesbaden, Germany
    Hepatogastroenterology 54:643-8. 2007
    ..The aim of the present study was to evaluate the prevalence of silent severe acute gastritis, gastric ulcers or erosions in asymptomatic patients with diabetes mellitus and to determine potential ..
  27. pmc Factors predicting progression of gastric intestinal metaplasia: results of a randomised trial on Helicobacter pylori eradication
    W K Leung
    Department of Medicine and Therapeutics, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, Hong Kong
    Gut 53:1244-9. 2004
    ..Gastric intestinal metaplasia (IM) is generally considered to be a precancerous lesion in the gastric carcinogenesis cascade. This study identified the risk factors associated with progression of IM in a randomised control study...
  28. ncbi Molecular epidemiology and outcome of Helicobacter pylori infection in Thailand: a cultural cross roads
    Ratha Korn Vilaichone
    Gastroenterology Unit, Department of Medicine, Thammasat University Hospital, Pathumthani, Thailand
    Helicobacter 9:453-9. 2004
    ..Chinese with gastric cancer or peptic ulcer disease had East Asian genotype, whereas only 40% of Chinese with gastritis had this genotype). Conclusions. Immigration, intermarriage and the variety of H...
  29. ncbi Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis
    Thomas Wultsch
    Research Unit of Translational Neurogastroenterology, Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitatsplatz 4, A 8010 Graz, Austria
    Pain 134:245-53. 2008
    ..Mild gastritis was induced by addition of iodoacetamide (0.1%) to the drinking water for 7 days...
  30. doi Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans
    Akinori Yanaka
    Division of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba ken, Tokyo, Japan
    Cancer Prev Res (Phila) 2:353-60. 2009
    ..pylori colonization in mice and improves the sequelae of infection in infected mice and in humans. This treatment seems to enhance chemoprotection of the gastric mucosa against H. pylori-induced oxidative stress...
  31. doi Increased number of methylated CpG islands correlates with Helicobacter pylori infection, histological and serological severity of chronic gastritis
    Tomomitsu Tahara
    Department of Gastroenterology, Kanazawa Medical University, Uchinadamachi, Kanazawa, Ishikawa, Japan
    Eur J Gastroenterol Hepatol 21:613-9. 2009
    ..Here, we examined whether methylation of multiple promoter CpG islands would occur by H. pylori infection and correlate with histological or serological severity of chronic gastritis.
  32. ncbi Neither gastric topological distribution nor principle virulence genes of Helicobacter pylori contributes to clinical outcomes
    Yan Wing Ho
    Department of Microbiology, Faculty of Medicine, National University of Singapore, 5 Science Drive 2, Singapore 117597, Republic of Singapore
    World J Gastroenterol 10:3274-7. 2004
    ..The aim of this study is to determine if the gastric topology and genotypic distribution of H pylori were associated with different upper gastrointestinal pathologies in a multiethnic Asian population...
  33. ncbi Relevance of vacA genotypes of Helicobacter pylori to cagA status and its clinical outcome
    S M Park
    Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea
    Korean J Intern Med 16:8-13. 2001
    ..specimens were obtained from 53 patients with gastric ulcer(GU), 57 with duodenal ulcer (DU) and 26 with chronic gastritis(CG) patients; all patients were infected with Helicobacter pylori...
  34. ncbi Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
    E Suri-Payer
    Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Harvard Medical School, 44 Binney Street, SM722, Boston, MA 02115, USA
    J Autoimmun 16:115-23. 2001
    Murine autoimmune gastritis, induced by neonatal thymectomy or the injection of CD25-depleted lymphocytes into nu/nu recipients, is characterized by an inflammatory infiltrate into the gastric mucosa, parietal cell destruction and ..
  35. pmc Enhanced expression of CCL20 in human Helicobacter pylori-associated gastritis
    Akira Yoshida
    Second Department of Internal Medicine, Nagasaki University School of Medicine, Sakamoto, Nagasaki 852 8501, Japan
    Clin Immunol 130:290-7. 2009
    ..pylori-infected and the uninfected groups. The CCL20 concentrations correlated with the degree of chronic gastritis. Immunohistochemistry and the in vitro infection assay showed that CCL20 was principally produced by the gastric ..
  36. ncbi Favourable effect of regular intake of fermented milk containing Lactobacillus johnsonii on Helicobacter pylori associated gastritis
    D Pantoflickova
    Division of Gastroenterology, University Hospital, Lausanne, Switzerland
    Aliment Pharmacol Ther 18:805-13. 2003
    Lactobacillus johnsonii (Lj1) had an in vitro and in vivo inhibitory effect on Helicobacter pylori. Fermented milk containing Lj1 (LC1), coadministered with antibiotics had a favourable effect on H. pylori gastritis.
  37. ncbi Methylation status of CDH1 gene in samples of gastric mucous from Brazilian patients with chronic gastritis infected by Helicobacter pylori
    Erika Kague
    Hemocentro, Faculdade de Medicina, UNESP, Botucatu, SP, Brazil
    Arq Gastroenterol 47:7-12. 2010
    ..Helicobacter pylori(H. pylori) is a class I carcinogen and infect almost 90% of chronic gastritis patients. Some genotypes confer different virulent potential to H...
  38. ncbi Characteristics of Helicobacter pylori-induced gastritis and the effect of H. pylori eradication in patients with chronic idiopathic thrombocytopenic purpura
    Takafumi Ando
    Department of Therapeutic Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Helicobacter 9:443-52. 2004
    ..We investigated the prevalence of H. pylori infection, its virulence profile and the effectiveness of its eradication in patients with ITP...
  39. doi The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach; particularly increasing in mucosae of Helicobacter-associated gastritis
    Toshiro Fukui
    The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University, 10 15 Fumizono cho, Moriguchi, Osaka 570 8506, Japan
    J Gastroenterol 46:456-68. 2011
    ..However, the lack of useful markers has hindered studies of their origin. We explored whether Smad2/3, phosphorylated at specific linker threonine residues (pSmad2/3L-Thr), could serve as a marker for stem cells...
  40. ncbi Topography of chronic active gastritis in Helicobacter pylori-positive Asian populations: age-, gender-, and endoscopic diagnosis-matched study
    Takeshi Matsuhisa
    Department of Gastrointestinal Endoscopy, Tama Nagayama Hospital, Nippon Medical School, 1 7 1 Nagayama, Tama, Tokyo 206 8512, Japan
    J Gastroenterol 39:324-8. 2004
    ..The aim of this study was to compare the degree of corpus-predominant gastritis, which is considered to be one of risk factors of gastric cancer, in Helicobacter pylori-positive Asian adult ..
  41. ncbi Duodenal intraepithelial lymphocytosis with normal villous architecture: common occurrence in H. pylori gastritis
    Lorenzo Memeo
    Department of Pathology, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY 10032, USA
    Mod Pathol 18:1134-44. 2005
    ..observed expansions of intraepithelial lymphocytes in duodenal biopsies from patients with Helicobacter pylori gastritis. This study was undertaken to prospectively evaluate, unselected, paired gastric and duodenal biopsies from 50 ..
  42. doi Murine models of H. pylori-induced gastritis and gastric adenocarcinoma
    Sabine Krueger
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Pathol Res Pract 207:599-607. 2011
    ..practical models have been established for the investigation of the initiation, expansion, and progression of gastritis and gastric carcinoma, for assessing the effects of bacterial, genetic and environmental factors, and for ..
  43. ncbi Inflammatory gene profiles in gastric mucosa during Helicobacter pylori infection in humans
    Sicheng Wen
    Department of Laboratory Medicine, Karolinska Institute at Huddinge Hospital, Stockholm, Sweden
    J Immunol 172:2595-606. 2004
    ..The expression data of the array hybridization was confirmed by quantitative real-time PCR assays. Future studies may help identify gene expression patterns predictive of complications of the infection...
  44. pmc Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study
    Khansa Ben Mansour
    Microbiology laboratory UR04SP08 Rabta University Hospital Tunis, 1007 El Jabbari, Tunisia
    Ann Clin Microbiol Antimicrob 9:22. 2010
    ..The frequency of primary resistance to antibiotics in H. pylori isolates is increasing worldwide. In Tunisia, there are limited data regarding the pattern of H. pylori antibiotic primary resistance...
  45. pmc Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation
    Gyeong Hoon Kang
    Department of Pathology and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Am J Pathol 163:1551-6. 2003
    ..Male patients showed higher numbers of methylated genes than females (3.2 vs. 2.1, respectively, P = 0.002). Gastritis samples with marked intestinal metaplasia, showed higher numbers of genes methylated than those without (3.7 vs...
  46. pmc Clinical Relevance of the vacA, iceA, cagA, and flaA genes of Helicobacter pylori strains isolated in Eastern Taiwan
    Chao Chuan Wu
    Department of Surgery, Tzu Chi University, Hualien 970, Taiwan
    J Clin Microbiol 43:2913-5. 2005
    ..of Helicobacter pylori flaA, cagA, vacA, and iceA were determined for DNA isolated from patients with chronic gastritis or peptic ulcer in eastern Taiwan...
  47. ncbi Eradication of Helicobacter pylori and resolution of gastritis in the gastric mucosa of IL-10-deficient mice
    Yuko Matsumoto
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Helicobacter 10:407-15. 2005
    ..The ability of IL-10(-/-) mice to eradicate H. pylori has not been demonstrated, possibly due to early sacrifice. Therefore, the long-term effect of enhanced gastritis on H. pylori colonization was determined in IL-10(-/-) mice.
  48. ncbi Presence of iceA1 but not cagA, cagC, cagE, cagF, cagN, cagT, or orf13 genes of Helicobacter pylori is associated with more severe gastric inflammation in Taiwanese
    Shew Meei Sheu
    Department of Microbiology and Immunology, National Cheng Kung University Medical College, Tainan, Taiwan
    J Formos Med Assoc 101:18-23. 2002
    ..This study determined the prevalence of genotypes of the PAI, IS605, and iceA1 in H. pylori strains in Taiwanese and whether these genotypes were related to the type of clinical disease or gastric pathology...
  49. doi Characterization of multiple Helicobacter bizzozeronii isolates from a Finnish patient with severe dyspeptic symptoms and chronic active gastritis
    Rauni Kivistö
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
    Helicobacter 15:58-66. 2010
    Helicobacter pylori is the primary cause of gastritis and peptic ulceration in humans...
  50. pmc Murine splenocytes induce severe gastritis and delayed-type hypersensitivity and suppress bacterial colonization in Helicobacter pylori-infected SCID mice
    K A Eaton
    Department of Veterinary Biosciences, Ohio State University, Columbus, Ohio 43210, USA
    Infect Immun 67:4594-602. 1999
    The goal of this study was to evaluate the role of host immunity in gastritis and epithelial damage due to Helicobacter pylori. Splenocytes from H. pylori-infected and uninfected C57BL/6 mice were adoptively transferred to H...
  51. pmc Classification of histological severity of Helicobacter pylori-associated gastritis by confocal laser endomicroscopy
    Peng Wang
    Department of Gastroenterology, Shandong University Qilu Hospital, Jinan 250012, Shandong Province, China
    World J Gastroenterol 16:5203-10. 2010
    To classify the histological severity of Helicobacter pylori (H. pylori) infection-associated gastritis by confocal laser endomicroscopy (CLE).
  52. ncbi Association between Helicobacter pylori Infection in gastric cancer, ulcers and gastritis in Iranian patients
    Farideh Siavoshi
    Helicobacter 9:470. 2004
  53. pmc Prevalence and genotypes of Helicobacter pylori in gastric biopsy specimens from patients with gastroduodenal pathologies in the Cukurova Region of Turkey
    Togrul Nagiyev
    Department of Microbiology, Faculty of Medicine, University of Cukurova, Adana, Turkey
    J Clin Microbiol 47:4150-3. 2009
    ..s1c allele, unlike in neighboring regions and countries, was found to be significantly higher in patients with gastritis and/or gastric ulcers (P = 0...
  54. ncbi Risk prediction of gastric cancer by analysis of aberrant DNA methylation in non-neoplastic gastric epithelium
    Tomomitsu Tahara
    Department of Gastroenterology, Fujita Health University School of Medicine, Dengakugakubo, Kutsukake cho, Toyoake, Aichi, Japan
    Digestion 75:54-61. 2007
    ..Promoter DNA methylation is also present in various non-neoplastic tissues including gastric epithelium as age-related phenomenon, suggesting that it occurs early in the process of tumorigenesis...
  55. ncbi Distribution of vacA genotypes in Helicobacter pylori strains isolated from Brazilian adult patients with gastritis, duodenal ulcer or gastric carcinoma
    Abdussalam A R Ashour
    Laboratory of Molecular Biology, Faculdade de Medicina, Universidade Federal de Minas Gerais, 30130 100, Belo Horizonte, Brazil
    FEMS Immunol Med Microbiol 33:173-8. 2002
    ..vacA s1b-m1 and cagA(+) strains were associated with higher prevalence of peptic ulcer and gastric carcinoma than vacA s2-m2 and cagA(-) ones. In conclusion, cagA and vacA genotyping may have clinical relevance in Brazil...
  56. pmc Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia
    Jennifer L Lofgren
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Gastroenterology 140:210-20. 2011
    ..FVB/N insulin-gastrin (INS-GAS) mice have high circulating gastrin levels, and develop spontaneous atrophic gastritis and gastrointestinal intraepithelial neoplasia (GIN) with 80% prevalence 6 months after Helicobacter pylori ..
  57. pmc Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis
    Dariush Nasrollahzadeh
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 6:e26957. 2011
    ..pylori) in Northern Iran, we performed an endoscopy-room-based validation study...
  58. pmc Helicobacter pylori CagA protein polymorphisms and their lack of association with pathogenesis
    Nicole Acosta
    Molecular Diagnostics and Bioinformatics Laboratory, Biological Sciences Department, Los Andes University, Carrera 1 18A 10, Bogota, Colombia
    World J Gastroenterol 16:3936-43. 2010
    ..To investigate Helicobacter pylori (H. pylori) CagA diversity and to evaluate the association between protein polymorphisms and the occurrence of gastric pathologies...
  59. ncbi Helicobacter pylori CagA status, mucosal oxidative damage and gastritis phenotype: a potential pathway to cancer?
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche Sezione di Gastroenterologia, Universita degli Studi di Padova, Italy
    Helicobacter 8:227-34. 2003
    ..Oxidative DNA damage is associated with Helicobacter pylori infection, atrophy and intestinal metaplasia. H. pylori-cagA-positive strains are associated with the highest risk of gastric cancer...
  60. ncbi Gastritis and carditis
    David A Owen
    University of British Columbia, Vancouver, British Columbia, Canada
    Mod Pathol 16:325-41. 2003
    ..Approximately 80% of gastroscopies are performed for the investigation of dyspepsia. "Gastritis" is diagnosed endoscopically in 59% of all stomachs, although in only 3% are the changes severe...
  61. ncbi The effect of gender on Helicobacter felis-mediated gastritis, epithelial cell proliferation, and apoptosis in the mouse model
    M Court
    Molecular Medicine Unit, St James s University Hospital, Leeds, UK
    J Pathol 201:303-11. 2003
    ..model has been extensively used to investigate the importance of host factors in the development of chronic gastritis. The effect of gender in this murine model is unknown...
  62. pmc Essential role for macrophage migration inhibitory factor in gastritis induced by Helicobacter pylori
    Benny L W Wong
    Department of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    Am J Pathol 174:1319-28. 2009
    ..regulator of immune and inflammatory responses; however, its role in Helicobacter pylori (HP)-associated gastritis remains unknown...
  63. doi Gastric Cancer Consensus conference recommends Helicobacter pylori screening and treatment in asymptomatic persons from high-risk populations to prevent gastric cancer
    Nicholas J Talley
    Department of Internal Medicine and Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida 32224, USA
    Am J Gastroenterol 103:510-4. 2008
    ..pylori in particularly high-risk population settings. The evidence for these recommendations is summarized in this report, and the global and U.S. implications are considered...
  64. pmc Functional analysis of the cag pathogenicity island in Helicobacter pylori isolates from patients with gastritis, peptic ulcer, and gastric cancer
    Steffen Backert
    Department of Medical Microbiology, Otto von Guericke University, D 39120 Magdeburg, Germany
    Infect Immun 72:1043-56. 2004
    ..Here, we have compared cagPAI-dependent in vitro responses in H. pylori isolates obtained from 75 patients with gastritis, peptic ulcer, and gastric cancer (n = 25 in each group)...
  65. pmc Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production
    Rupesh Chaturvedi
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Gastroenterology 139:1686-98, 1698.e1-6. 2010
    ..We determined if spermine inhibits iNOS-mediated immunity by reducing L-Arg uptake into macrophages...
  66. pmc Why does Japan have a high incidence of gastric cancer? Comparison of gastritis between UK and Japanese patients
    G M Naylor
    Chesterfield Royal Hospital, Chesterfield, N Derbyshire S44 5BL, UK
    Gut 55:1545-52. 2006
    ..We hypothesised that a Japanese population would have a more severe gastritis with a corpus predominant or pangastritis pattern and a greater degree of atrophy and intestinal metaplasia than ..
  67. pmc Eosinophil infiltration, gastric juice and serum eosinophil cationic protein levels in Helicobacter pylori-associated chronic gastritis and gastric ulcer
    Selim A Aydemir
    Department of Gastroenterology, Zonguldak Karaelmas University, Faculty of Medicine, Ic Hastaliklari ABD, Gastroenteroloji BD, 67800 Zonguldak, Turkey
    Mediators Inflamm 13:369-72. 2004
    Helicobacter pylori is one of the main causes of gastroduodenal diseases, such as chronic gastritis and peptic ulcer. It has been shown that eosinophils increase in the stomach in H. pylori infection...
  68. ncbi Impaired production of gastric ghrelin in chronic gastritis associated with Helicobacter pylori
    Hiroyuki Osawa
    Department of Internal Medicine, Division of Gastroenterology, Jichi Medical School, 3311 1 Yakushiji, Minamikawachi, Kawachi, Tochigi, Japan 329 0498
    J Clin Endocrinol Metab 90:10-6. 2005
    ..pylori-positive subjects. These findings suggest that impaired gastric ghrelin production in association with atrophic gastritis induced by H. pylori infection accounts for the decrease in plasma ghrelin concentration.
  69. ncbi Gastric ghrelin expression associated with Helicobacter pylori infection and chronic gastritis in obese patients
    Phui Ly Liew
    Department of Pathology, En Chu Kong Hospital, No 399 Fu hsing Road, San shia Town, Taipei Hsien 237, Taiwan
    Obes Surg 16:612-9. 2006
    ..pylori infection to ghrelin, then to obesity. The aim of the present study is to investigate gastric ghrelin immunoreactivity associated with H. pylori infection, chronic gastritis and the clinical correlation in obese patients.
  70. pmc Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia
    Torsten K Roepke
    Department of Pharmacology, Weill Medical College of Cornell University, New York, New York, United States of America
    PLoS ONE 5:e11451. 2010
    ..Kcne2(-/-) mice in a pathogen-free environment all exhibit a severe gastric preneoplastic phenotype comprising gastritis cystica profunda, 6-fold increased stomach mass, increased Ki67 and nuclear Cyclin D1 expression, and TFF2- and ..
  71. ncbi Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis
    Peter Hofner
    Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary
    Helicobacter 12:124-31. 2007
    ..The aim of this study was to evaluate the relationship between NOD1 and IL-8 genetic polymorphisms and the development of H. pylori-induced gastritis and duodenal ulcer (DU), as compared with TLR4 polymorphisms.
  72. ncbi Nodular gastritis in adults: clinical features, endoscopic appearance, histopathological features, and response to therapy
    Manisha Dwivedi
    Departments of Gastroenterology and Pathology, Moti Lal Nehru Medical College, University of Allahabad, Allahabad, India
    J Gastroenterol Hepatol 23:943-7. 2008
    The present study aims to determine the prevalence of nodular gastritis (NG) and ascertain its clinical presentation and histopathological features in adults...
  73. ncbi Variation in serum pepsinogens with severity and topography of Helicobacter pylori-associated chronic gastritis in dyspeptic patients referred for endoscopy
    K Bodger
    Division of Medicine, and Pathology Department, St James' University Hospital Beckett St, Leeds, UK
    Helicobacter 6:216-24. 2001
    BACKGROUND: It has long been recognised that specific patterns of gastritis are linked with different gastroduodenal diseases and that serum pepsinogens vary with the histological state of the gastric mucosa...
  74. ncbi Myocarditis presenting as gastritis in children
    Yi Jung Chang
    Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tauyuan, Taiwan
    Pediatr Emerg Care 22:439-40. 2006
    ..associated with abdominal pain or vomiting remains a diagnostic challenge to physicians, it should be considered in the differential diagnosis of children with gastritis and hypotension or who are refractory to rehydration therapy.
  75. pmc Frequency of vacA, cagA and babA2 virulence markers in Helicobacter pylori strains isolated from Mexican patients with chronic gastritis
    Gloria Luz Paniagua
    Universidad Nacional Autonoma de Mexico, Los Reyes Iztacala, Tlalnepantla, Estado de Mexico, Mexico
    Ann Clin Microbiol Antimicrob 8:14. 2009
    Helicobacter pylori has been strongly associated with chronic gastritis, peptic and duodenal ulcers, and it is a risk factor for gastric cancer. Three major virulence factors of H...
  76. ncbi Experimental gastritis in mice enhances anxiety in a gender-related manner
    E Painsipp
    Research Unit of Translational Neurogastroenterology, Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitatsplatz 4, A 8010 Graz, Austria
    Neuroscience 150:522-36. 2007
    ..inflammation on the emotional-affective behavior is little known, we examined whether experimental gastritis modifies anxiety, stress coping and circulating corticosterone in male and female Him:OF1 mice...
  77. doi Effects of Helicobacter pylori infection on the expressions of Bax and Bcl-2 in patients with chronic gastritis and gastric cancer
    Waldemar Bartchewsky
    Unidade Integrada de Farmacologia e Gastroenterologia, Universidade São Francisco, Av São Francisco de Assis, 218 Jd São José, Braganca Paulista, SP, Brazil
    Dig Dis Sci 55:111-6. 2010
    ..evaluate the influence of Helicobacter pylori on Bax and Bcl-2 mRNA and protein levels in patients with chronic gastritis and gastric cancer...
  78. doi Serum pepsinogen I, pepsinogen II, and gastrin 17 in relatives of gastric cancer patients: comparative study with type and severity of gastritis
    Arghavan Haj-Sheykholeslami
    Department of Gastroenterology, Digestive Disease Research Center, Shariati Hospital, Tehran, Iran
    Clin Gastroenterol Hepatol 6:174-9. 2008
    ..The aim of this study was to investigate the potential of biomarkers pepsinogen I (PGI), pepsinogen II (PGII), their ratio (PG I:II), as well as gastrin 17 for screening of precancerous conditions and corpus predominant gastritis.
  79. ncbi Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma
    Yana Zavros
    Department of Gastroenterology, University of Michigan, Ann Arbor, MI 48109 0650, USA
    Oncogene 24:2354-66. 2005
    The current study tests the hypothesis that chronic atrophic gastritis from hypochlorhydria in the gastrin-deficient mouse predisposes the stomach to gastric cancer...
  80. ncbi Pathogenic effector T cell enrichment overcomes regulatory T cell control and generates autoimmune gastritis
    Joao P Monteiro
    Divisão de Medicina Experimental, Coordenação de Pesquisa, Instituto Nacional de Cancer, Rio de Janeiro, Brazil
    J Immunol 181:5895-903. 2008
    ..Postneonatal thymectomy autoimmune gastritis has also been attributed to the absence of Tregs...
  81. doi Prevention of chronic gastritis by fermented milks made with exopolysaccharide-producing Streptococcus thermophilus strains
    C Rodriguez
    Centro de Referencia para Lactobacilos CONICET, Chacabuco 145, San Miguel de Tucuman, 4000 Tucuman, Argentina
    J Dairy Sci 92:2423-34. 2009
    Acetyl-salicylic acid (ASA) is a nonsteroidal antiinflammatory/analgesic drug, which may cause gastritis or stomach ulcers if intensively employed...
  82. ncbi Low plasma ghrelin levels in patients with Helicobacter pylori-associated gastritis
    Hajime Isomoto
    Second Department of Internal Medicine, Atomic Bomb Disease Institute, Nagasaki University School of Medicine, Japan
    Am J Med 117:429-32. 2004
  83. pmc Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis
    Dinorah N Martínez-Carrillo
    Laboratorio de Investigación Clínica, Unidad Académica de Ciencias Químico Biológicas, Universidad Autonoma de Guerrero, Av, Lázaro Cárdenas S N, Ciudad Universitaria, Colonia Haciendita, Chilpancingo, Guerrero, C, P, 39090, Mexico
    BMC Gastroenterol 10:126. 2010
    ..Our objective was to determine if the IL-1B -511 T>C and -31 C>T polymorphisms and H. pylori vacA genotypes are associated with risk of chronic gastritis and gastric ulcer in a Mexican population.
  84. ncbi Gastric neuroendocrine carcinoma associated with atrophic gastritis in the norwegian lundehund
    G Qvigstad
    Department of Gastroenterology and Hepatology, St Olav s Hospital, Trondheim University Hospital, N 7006 Trondheim
    J Comp Pathol 139:194-201. 2008
    In humans and rodents the association between atrophic gastritis, hypergastrinemia and gastric neoplasia is well-documented...
  85. doi OLGA gastritis staging in young adults and country-specific gastric cancer risk
    Massimo Rugge
    Department of Medical Diagnostic Sciences and Special Therapies II Pathology Unit, University of Padova, Italy
    Int J Surg Pathol 16:150-4. 2008
    Geographical differences have been shown in the clinical outcomes of Helicobacter pylori-associated gastritis phenotypes and in gastric cancer risk...
  86. doi Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography
    Yoshiaki Matsumoto
    Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Gastroenterol 43:332-7. 2008
    ..Few reports discuss gastric motility in relation to histologic gastritis. We examined the relation between gastric motility and histologic gastritis in Japanese patients with FD.
  87. doi Helicobacter pylori and gastritis: Untangling a complex relationship 27 years on
    Victoria P Y Tan
    Department of Medicine, University of Hong Kong, China
    J Gastroenterol Hepatol 26:42-5. 2011
    ..Helicobacter pylori (HP) has become the linchpin in our understanding of important gastric conditions including gastritis, intestinal metaplasia (IM), gastric/duodenal ulcers (GU/DU), Mucosal Associated Lymphoid Tumour (MALToma) and ..
  88. ncbi Dyspepsia in HIV-infected patients under highly active antiretroviral therapy
    Ana Luiza Werneck-Silva
    Casa da AIDS Infectious Disease Division, School of Medicine, University of Sao Paulo, Brazil
    J Gastroenterol Hepatol 22:1712-6. 2007
    ..We have done a prospective study of the prevalence and the etiology of endoscopic lesions in a large cohort of dyspeptic adult HIV-infected patients under HAART, according to their immunological status...
  89. ncbi Gastric acidity in patients with follicular gastritis is significantly reduced, but can be normalized after eradication for Helicobacter pylori
    Tomohiko Shimatani
    Department of General Medicine, Hiroshima University Hospital, Hiroshima, Japan
    Helicobacter 10:256-65. 2005
    Follicular gastritis is thought to be caused by Helicobacter pylori infection. However, the pathophysiology of it remains unclear.
  90. ncbi Helicobacter pylori infection, histopathological gastritis and gastric epithelial cell apoptosis in children
    Manisha Singh
    Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Acta Paediatr 95:732-7. 2006
    Features of gastritis and gastric epithelial cell apoptosis in children infected with Helicobacter pylori genotypes are seldom studied...
  91. ncbi gammadelta T cells increase with gastric mucosal interleukin (IL)-7, IL-1beta, and Helicobacter pylori urease specific immunoglobulin levels via CCR2 upregulation in Helicobacter pylori gastritis
    Seiji Futagami
    Third Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    J Gastroenterol Hepatol 21:32-40. 2006
    ..The purpose of this study was to investigate possible factors that could impact on gammadelta T cell accumulation in the gastric mucosa...
  92. pmc Red wine and green tea reduce H pylori- or VacA-induced gastritis in a mouse model
    Paolo Ruggiero
    Novartis Vaccines and Diagnostics s r l, Research Center, Via Fiorentina 1, Siena I 53100, Italy
    World J Gastroenterol 13:349-54. 2007
    ..To investigate whether red wine and green tea could exert anti-H pylori or anti-VacA activity in vivo in a mouse model of experimental infection...
  93. pmc Influence of H pylori on plasma ghrelin in patients without atrophic gastritis
    Mehmet Cindoruk
    Gazi University, Department of Gastroenterology, Ankara, Turkey
    World J Gastroenterol 13:1595-8. 2007
    To determine the association between H pylori infection and serum ghrelin levels in patients without atrophic gastritis.
  94. doi Bioinformatics research on chronic superficial gastritis of Pi-deficiency syndrome by gene arrays
    Yu Long Chen
    Pi Wei Institute, Guangzhou University of Chinese Medicine, Guangzhou, China
    Chin J Integr Med 15:341-6. 2009
    ..the bioinformatical characteristics of differential gene expression in patients with chronic superficial gastritis (CSG) with the Pi-deficiency syndrome (PDS) and those of the non-Pi-deficiency syndrome (non-PDS), i.e...
  95. ncbi Xanthogranulomatous gastritis with pseudosarcomatous changes
    Hitoshi Kubosawa
    Department of Pathology, Aoba Hospital, Chiba, Japan
    Pathol Int 57:291-5. 2007
    ..Although the precise pathogenesis could not be elucidated, recognition of this unusual morphological appearance is of importance to avoid an overdiagnosis of malignancy...
  96. pmc Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non-steroidal anti-inflammatory drug use
    Xiao Xing Li
    Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China
    PLoS ONE 4:e7985. 2009
    ..Helicobacter pylori infection and non-steroidal anti-inflammatory drug (NSAID) use are two main contributors to gastritis and peptic ulcer...
  97. pmc Isocitrate dehydrogenase of Helicobacter pylori potentially induces humoral immune response in subjects with peptic ulcer disease and gastritis
    M Abid Hussain
    Pathogen Evolution Laboratory, Centre for DNA Fingerprinting and Diagnostics CDFD, Hyderabad, India
    PLoS ONE 3:e1481. 2008
    H. pylori causes gastritis and peptic ulcers and is a risk factor for the development of gastric carcinoma...
  98. pmc Gastrin (G) cells and somatostatin (D) cells in patients with dyspeptic symptoms: Helicobacter pylori associated and non-associated gastritis
    Y Liu
    Department of Pathology, Academic Medical Centre, University of Amsterdam, 1100 DD Amsterdam, The Netherlands
    J Clin Pathol 58:927-31. 2005
    ..Gastrin G cells and somatostatin D cells are important regulators of gastric acid secretion and alterations in their relative numbers may play a key role in gastroduodenal disease...
  99. pmc Therapeutic effect of Streptococcus thermophilus CRL 1190-fermented milk on chronic gastritis
    Cecilia Rodriguez
    Centro de Referencia para Lactobacilos CERELA CONICET, Chacabuco 145, San Miguel de Tucuman, 4000, Tucuman, Argentina
    World J Gastroenterol 16:1622-30. 2010
    To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice.
  100. ncbi Overexpression of p73 as a tissue marker for high-risk gastritis
    Gonzalo Carrasco
    Department of Anatomic Pathology, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Clin Cancer Res 16:3253-9. 2010
    Histologic assessment of high-risk gastritis for the development of gastric cancer is not well defined. The identification of tissue markers together with the integration of histologic features will be required for this assessment.
  101. ncbi Molecular typing of Campylobacter jejuni and C. coli from chickens and patients with gastritis or Guillain-Barré syndrome based on multilocus sequence types and pulsed-field gel electrophoresis patterns
    Shizuka Yabe
    Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata 951 8510, Japan
    Microbiol Immunol 54:362-7. 2010
    ..C. coli from enteritis was also divergent. Novel ST types may represent unidentified native clones in each country. Pulsed-field gel electrophoresis confirmed the above typing and demonstrated long-term persistence and transmission...

Research Grants79

  1. Etiological Studies of Gastric Carcinoma
    Pelayo Correa; Fiscal Year: 2003
    ..Clinical infections may lead to duodenal ulcer accompanied by non-atrophic gastritis, which does not increase gastric cancer risk, or to multifocal atrophic gastritis, which may lead to gastric ..
  2. Etiological Studies of Gastric Carcinoma
    Pelayo Correa; Fiscal Year: 2005
    ..Clinical infections may lead to duodenal ulcer accompanied by non-atrophic gastritis, which does not increase gastric cancer risk, or to multifocal atrophic gastritis, which may lead to gastric ..
  3. H pylori induced oxidative DNA damage
    Duane Smoot; Fiscal Year: 2001
    ..Progression from superficial gastritis caused by H...
  4. AGE-RELATED GASTRIC CHANGES AND DRUG ABSORPTION
    Aryeh Hurwitz; Fiscal Year: 1993
    ..Serum pepsinogen and gastrin levels will be used as indicators of atrophic gastritis, and inability to secrete acid...
  5. AGE-RELATED GASTRIC CHANGES AND DRUG ABSORPTION
    Aryeh Hurwitz; Fiscal Year: 1991
    ..Serum pepsinogen and gastrin levels will be used as indicators of atrophic gastritis, and inability to secrete acid...
  6. PH III: CELLCEPT IN LIVER TRANSPLANT W/ RENAL IMPAIRMENT ON NEORAL
    Pierre Clavien; Fiscal Year: 1999
    ..The major side effects of MMF are dose related gastritis, leukopenia, and anemia...
  7. GASTRIC ACID SECRETION AND BUFFER CONTENT AFTER EATING
    Mark Feldman; Fiscal Year: 1990
    ..g. espphagitis, gastritis). The economic impact of acid-peptic diseases is tremendous...
  8. FIMBRIAL ADHESINS OF HELICOBACTER PYLORI
    TREVOR TRUST; Fiscal Year: 1992
    ..The diseases include gastritis, and gastric and duodenal ulcers. Since the diseases associated with H...
  9. THE ROLE OF CELL SHAPE AND CELL WALL IN HELICOBACTER PYLORI PATHOGENESIS
    Nina Salama; Fiscal Year: 2009
    ..pylori is a helical bacterium that colonizes the human stomach causing clinical outcomes ranging from mild gastritis to peptic ulcer and gastric cancer. Descriptions of H...
  10. THE ROLE OF CELL SHAPE AND CELL WALL IN HELICOBACTER PYLORI PATHOGENESIS
    NINA REDA SALAMA; Fiscal Year: 2010
    ..pylori is a helical bacterium that colonizes the human stomach causing clinical outcomes ranging from mild gastritis to peptic ulcer and gastric cancer. Descriptions of H...
  11. UREASE AND GENE EXPRESSION IN CAMPYLOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 1990
    ..pylori, a spiral-shaped gram-negative microaerophilic rod, is not postulated to be an etiological agent of gastritis and peptic ulcer disease...
  12. UREASE AND GENE EXPRESSION IN CAMPYLOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 1991
    ..pylori, a spiral-shaped gram-negative microaerophilic rod, is not postulated to be an etiological agent of gastritis and peptic ulcer disease...
  13. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2007
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  14. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2006
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  15. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2004
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  16. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2005
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  17. Prophylactic and Therapeutic Immunization against H. pylori in Rhesus Macaques
    JAY SOLNICK; Fiscal Year: 2007
    ..provided by applicant): Helicobacter pylori commonly infects the human stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some...
  18. Genetic and Biochemical Analysis of DNA Exchange in Helicobacter pylori
    MARION SHONN DORER; Fiscal Year: 2010
    ..Inflammation caused by H. pylori puts the infected population at increased risk for chronic gastritis, peptic ulcer disease, and gastric cancers, the second leading cause of cancer-related deaths in the world [2]...
  19. EFFECTS OF DIETARY POLYUNSATURATED FAT ON HELICOBACTER PYLORI
    Duane Smoot; Fiscal Year: 1999
    Helicobacter pylori (H. pylori) infection is the most common cause of chronic gastritis in man, and it has been implicated as an etiological factor in the development of peptic ulcer disease...
  20. EFFECTS OF DIETARY POLYUNSATURATED FAT ON HELICOBACTER PYLORI
    Duane Smoot; Fiscal Year: 2000
    Helicobacter pylori (H. pylori) infection is the most common cause of chronic gastritis in man, and it has been implicated as an etiological factor in the development of peptic ulcer disease...
  21. SC-58635 compared to diclofenac in osteoarthritis or rheumatoid arthritis
    Alan Friedman; Fiscal Year: 2000
    ..also inhibit this enzyme, but in addition, they inhibit cyclooxygenase-1, which leads to the side effects (gastritis, ulcers, blood ""thinning"") seen with NSAID use...
  22. CAMPYLOBACTER PYLORIDIS IN GASTRODUODENAL DISEASE
    David Graham; Fiscal Year: 1990
    ..The presence of C. pyloridis in the stomach has been associated with peptic ulcer disease, non-ulcer dyspepsia and gastritis. Detection of the organism by either bacterial culture or histologic examination has required invasive ..
  23. H PYLORI AND GASTRIC PRENEOPLASTIC LESIONS
    Julie Parsonnet; Fiscal Year: 1999
    ..incidence in developing countries, is preceded by a sequence of histologic changes including chronic atrophic gastritis (CAG), intestinal metaplasia (IM), and dysplasia...
  24. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2001
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  25. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2003
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  26. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 1999
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  27. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2000
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  28. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2002
    ..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
  29. BACTERIAL INDUCED COLITIS IN HLA-B27 RATS
    LEVINUS DIELEMAN; Fiscal Year: 1999
    ..Our hypothesis is that chronic colitis and gastritis is the result of an overly aggressive immune response to luminal bacteria in a genetically susceptible host...
  30. Modulation of Outer Membrane Protein Expressin in Helicobacter pylori
    JAY SOLNICK; Fiscal Year: 2009
    ..provided by applicant): Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some. H...
  31. BACTERIAL INDUCED COLITIS IN HLA-B27 RATS
    LEVINUS DIELEMAN; Fiscal Year: 2002
    ..Our hypothesis is that chronic colitis and gastritis is the result of an overly aggressive immune response to luminal bacteria in a genetically susceptible host...
  32. BACTERIAL INDUCED COLITIS IN HLA-B27 RATS
    LEVINUS DIELEMAN; Fiscal Year: 2001
    ..Our hypothesis is that chronic colitis and gastritis is the result of an overly aggressive immune response to luminal bacteria in a genetically susceptible host...
  33. Modulation of Outer Membrane Protein Expressin in Helicobacter pylori
    JAY SOLNICK; Fiscal Year: 2009
    ..provided by applicant): Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some. H...
  34. Modulation of Outer Membrane Protein Expressin in Helicobacter pylori
    Jay V Solnick; Fiscal Year: 2010
    ..provided by applicant): Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some. H...
  35. BACTERIAL INDUCED COLITIS IN HLA-B27 RATS
    LEVINUS DIELEMAN; Fiscal Year: 2000
    ..Our hypothesis is that chronic colitis and gastritis is the result of an overly aggressive immune response to luminal bacteria in a genetically susceptible host...
  36. Acetone metabolism in Helicobacter pylori
    Timothy Hoover; Fiscal Year: 2004
    ..human pathogen that colonizes the gastric mucosa, leading to gastric inflammation that can progress to chronic gastritis, peptic ulcer, gastric cancer or mucosal-associated lymphoma. The ability of H...
  37. Acetone metabolism in Helicobacter pylori
    Timothy Hoover; Fiscal Year: 2003
    ..human pathogen that colonizes the gastric mucosa, leading to gastric inflammation that can progress to chronic gastritis, peptic ulcer, gastric cancer or mucosal-associated lymphoma. The ability of H...
  38. A Novel Wireless Capsule Camera with High Resolution Optically Unwrapped 360-Degr
    Jason Geng; Fiscal Year: 2010
    ..g. hiatal hernia, gastritis, ulcers, polyps, stomach/colon cancer...
  39. MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDES
    MICHAEL TRENT; Fiscal Year: 2006
    ..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
  40. A Novel Wireless Capsule Camera with High Resolution Optically Unwrapped 360-Degr
    Jason Geng; Fiscal Year: 2009
    ..g. hiatal hernia, gastritis, ulcers, polyps, stomach/colon cancer...
  41. H pylori induced oxidative DNA damage
    John Groopman; Fiscal Year: 2001
    ..Progression from superficial gastritis caused by H...
  42. H.pylori arginase modulation of ulcers and cancer
    David McGee; Fiscal Year: 2005
    Helicobacter pylori infects approximately 50% of the human population, causing severe gastric diseases including gastritis, peptic ulcers, and gastric cancer. H...
  43. H.pylori arginase modulation of ulcers and cancer
    David McGee; Fiscal Year: 2006
    Helicobacter pylori infects approximately 50% of the human population, causing severe gastric diseases including gastritis, peptic ulcers, and gastric cancer. H...
  44. H.pylori arginase modulation of ulcers and cancer
    David McGee; Fiscal Year: 2007
    Helicobacter pylori infects approximately 50% of the human population, causing severe gastric diseases including gastritis, peptic ulcers, and gastric cancer. H...
  45. H.pylori arginase modulation of ulcers and cancer
    David McGee; Fiscal Year: 2004
    Helicobacter pylori infects approximately 50% of the human population, causing severe gastric diseases including gastritis, peptic ulcers, and gastric cancer. H...
  46. H.pylori arginase modulation of ulcers and cancer
    David McGee; Fiscal Year: 2003
    Helicobacter pylori infects approximately 50% of the human population, causing severe gastric diseases including gastritis, peptic ulcers, and gastric cancer. H...
  47. Oxidative Injury to Gastric Epithelial Cells by H. pylori
    Sheila Crowe; Fiscal Year: 2009
    Helicobacter pylori causes gastritis, peptic ulcer disease, gastric carcinoma, and gastric lymphoma, however, only a subset of infected individuals develops disease in the form of ulceration or adenocarcinoma...
  48. Oxidative Injury to Gastric Epithelial Cells by H. pylori
    Sheila E Crowe; Fiscal Year: 2010
    Helicobacter pylori causes gastritis, peptic ulcer disease, gastric carcinoma, and gastric lymphoma, however, only a subset of infected individuals develops disease in the form of ulceration or adenocarcinoma...
  49. Oxidative Injury to Gastric Epithelial Cells by H. pylori
    Sheila Crowe; Fiscal Year: 2009
    Helicobacter pylori causes gastritis, peptic ulcer disease, gastric carcinoma, and gastric lymphoma, however, only a subset of infected individuals develops disease in the form of ulceration or adenocarcinoma...
  50. Risk factors for gastric disease in pediatric H. pylori
    Benjamin Gold; Fiscal Year: 2006
    DESCRIPTION (provided by applicant): Helicobacter pylori (Hp) is a major cause of chronic-active gastritis, primary duodenal ulcers and strongly linked to gastric cancer. Most Hp infections worldwide are acquired in childhood...
  51. Risk factors for gastric disease in pediatric H. pylori
    Benjamin Gold; Fiscal Year: 2004
    Helicobacter pylori (Hp) is a major cause of chronic-active gastritis, primary duodenal ulcers and strongly linked to gastric cancer. Most Hp infections worldwide are acquired in childhood...
  52. Risk factors for gastric disease in pediatric H. pylori
    Benjamin Gold; Fiscal Year: 2005
    Helicobacter pylori (Hp) is a major cause of chronic-active gastritis, primary duodenal ulcers and strongly linked to gastric cancer. Most Hp infections worldwide are acquired in childhood...
  53. MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDES
    MICHAEL STEPHEN TRENT; Fiscal Year: 2010
    ..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
  54. MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDES
    MICHAEL TRENT; Fiscal Year: 2009
    ..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
  55. MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDES
    MICHAEL TRENT; Fiscal Year: 2007
    ..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
  56. H. PYLORI INFECTION AND GI DISEASE IN ALASKA NATIVES
    Douglas Berg; Fiscal Year: 2002
    ..It is the major cause of severe gastritis and peptic ulcers, and a risk factor for gastric cancer, although most infections are asymptomatic...
  57. H. PYLORI INFECTION AND GI DISEASE IN ALASKA NATIVES
    Douglas Berg; Fiscal Year: 2003
    ..It is the major cause of severe gastritis and peptic ulcers, and a risk factor for gastric cancer, although most infections are asymptomatic...
  58. H. PYLORI INFECTION AND GI DISEASE IN ALASKA NATIVES
    Douglas Berg; Fiscal Year: 2001
    ..It is the major cause of severe gastritis and peptic ulcers, and a risk factor for gastric cancer, although most infections are asymptomatic...
  59. H. PYLORI INFECTION AND GI DISEASE IN ALASKA NATIVES
    Douglas Berg; Fiscal Year: 2000
    ..It is the major cause of severe gastritis and peptic ulcers, and a risk factor for gastric cancer, although most infections are asymptomatic...
  60. H. PYLORI INFECTION AND GI DISEASE IN ALASKA NATIVES
    Douglas Berg; Fiscal Year: 1999
    ..It is the major cause of severe gastritis and peptic ulcers, and a risk factor for gastric cancer, although most infections are asymptomatic...
  61. HOST RESPONSE TO HELICOBACTER PYLORI INFECTION
    Pelayo Correa; Fiscal Year: 2000
    b>Gastritis due to Helicobacter Pylori is the most common chronic infection in the world today. It has been classified by IARC (WHO) as a Class I human carcinogen...
  62. HOST RESPONSE TO HELICOBACTER PYLORI INFECTION
    Pelayo Correa; Fiscal Year: 1999
    b>Gastritis due to Helicobacter Pylori is the most common chronic infection in the world today. It has been classified by IARC (WHO) as a Class I human carcinogen...
  63. IN VIVO PATHOGENESIS OF HELICOBACTER PYLORI
    James Fox; Fiscal Year: 2007
    ..Clinical and epidemiologic studies suggest that the development of atrophic gastritis intestinal metaplasia and dysplasia represent essential steps in the cascade of events leading to gastric cancer...
  64. IN VIVO PATHOGENESIS OF HELICOBACTER PYLORI
    James Fox; Fiscal Year: 2009
    ..Clinical and epidemiologic studies suggest that the development of atrophic gastritis intestinal metaplasia and dysplasia represent essential steps in the cascade of events leading to gastric cancer...
  65. IN VIVO PATHOGENESIS OF HELICOBACTER PYLORI
    James Fox; Fiscal Year: 2005
    ..Clinical and epidemiologic studies suggest that the development of atrophic gastritis intestinal metaplasia and dysplasia represent essential steps in the cascade of events leading to gastric cancer...
  66. MUCOSAL IMMUNOLOGY OF HELICOBACTER INDUCED GASTRITIS
    Steven Czinn; Fiscal Year: 2007
    Helicobacter pylori (H. pylori) is a major cause of chronic active gastritis, primary peptic ulcer disease, and is strongly linked to gastric cancer. Individuals infected with H...
  67. H.pylori arginase modulation of ulcers and cancer
    David McGee; Fiscal Year: 2005
    Helicobacter pylori infects approximately 50% of the human population, causing severe gastric diseases including gastritis, peptic ulcers, and gastric cancer. H...
  68. IMMUNE RESPONSE TO H PYLORI GASTRITIS
    Augusto Ochoa; Fiscal Year: 2003
    ..pylori) infects over half of the world's population and is associated with multiple disease states ranging from gastritis and duodenal ulcer to gastric cancer and lymphomas...
  69. H. Pylori Induced Oxidative Stress
    Keith Wilson; Fiscal Year: 2009
    ..SMO and oxidative DNA damage in gastric epithelial cells in vitro that correlates with similar findings in the gastritis tissues from the source patients for these strains...
  70. Helicobacter pylori and the gastric microbial community in rhesus macaques
    Jay V Solnick; Fiscal Year: 2010
    Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some...
  71. PREVALENCE OF HELICOBACTER PYLORI: ARE EMERGENCY MEDICINE RESIDENTS A
    Mauricio Martinez; Fiscal Year: 1999
    ..pylori, an organism in the gastro-intestinal tract, has been strongly associated with peptic ulcer disease, gastritis, and gastric cancer. The microbiology of gastrointestinal disease reemerged as a field of interest when H...
  72. Helicobacter pylori and the gastric microbial community in rhesus macaques
    JAY SOLNICK; Fiscal Year: 2009
    Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some...
  73. A Novel In-Vivo Capsule Camera with High Resolution Optically Unwarpped 360-Degre
    Jason Geng; Fiscal Year: 2007
    ..g. hiatal hernia, gastritis, ulcers, polyps, stomach/colon cancer...
  74. Mechanisms of Growth Inhibition by Helicobacter Pylori
    Hassan Ashktorab; Fiscal Year: 2002
    ..Epidemiological data supports this bacterium as a cofactor because it causes chronic gastritis which may progress to atrophic gastritis, a precursor lesion for intestinal type gastric cancer...
  75. Mechanisms of Growth Inhibition by Helicobacter Pylori
    Hassan Ashktorab; Fiscal Year: 2001
    ..Epidemiological data supports this bacterium as a cofactor because it causes chronic gastritis which may progress to atrophic gastritis, a precursor lesion for intestinal type gastric cancer...