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| gastritisSummarySummary: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders. Top Publications
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Publications
A simple multiplex PCR assay for diagnosing virulent Helicobacter pylori infection in human gastric biopsy specimens from subjects with gastric carcinoma and other gastro-duodenal diseasesS K Tiwari
Center for Liver Research and Diagnostics, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad, Andhra Pradesh, India
J Appl Microbiol 103:2353-60. 2007..To evaluate and develop a multiplex polymerase chain reaction (PCR) assay for diagnosing and specific identification of virulent Helicobacter pylori strains and their main virulence genes cagA, cagE, cagT, vacA and hrgA...
Helicobacter pylori infection and the development of gastric cancerN Uemura
Department of Gastroenterology, Kure Kyosai Hospital, Kure City, Japan
N Engl J Med 345:784-9. 2001..Although many studies have found an association between Helicobacter pylori infection and the development of gastric cancer, many aspects of this relation remain uncertain...
Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countriesY Yamaoka
Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
J Clin Microbiol 37:2274-9. 1999..obtained from patients with different clinical presentations (peptic ulcer, gastric cancer, and atrophic gastritis). The H. pylori isolates examined included 107 strains from Bogota, Colombia, 70 from Houston, Tex...
Nodular gastritis in adults: clinical features, endoscopic appearance, histopathological features, and response to therapyManisha Dwivedi
Departments of Gastroenterology and Pathology, Moti Lal Nehru Medical College, University of Allahabad, Allahabad, India
J Gastroenterol Hepatol 23:943-7. 2008The present study aims to determine the prevalence of nodular gastritis (NG) and ascertain its clinical presentation and histopathological features in adults...
Why does Japan have a high incidence of gastric cancer? Comparison of gastritis between UK and Japanese patientsG M Naylor
Chesterfield Royal Hospital, Chesterfield, N Derbyshire S44 5BL, UK
Gut 55:1545-52. 2006..We hypothesised that a Japanese population would have a more severe gastritis with a corpus predominant or pangastritis pattern and a greater degree of atrophy and intestinal metaplasia than ..
Gastric ghrelin expression associated with Helicobacter pylori infection and chronic gastritis in obese patientsPhui Ly Liew
Department of Pathology, En Chu Kong Hospital, No 399 Fu hsing Road, San shia Town, Taipei Hsien 237, Taiwan
Obes Surg 16:612-9. 2006..pylori infection to ghrelin, then to obesity. The aim of the present study is to investigate gastric ghrelin immunoreactivity associated with H. pylori infection, chronic gastritis and the clinical correlation in obese patients.
Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide ProductionRupesh Chaturvedi
Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Gastroenterology 139:1686-98, 1698.e1-6. 2010..We determined if spermine inhibits iNOS-mediated immunity by reducing L-Arg uptake into macrophages...
Functional analysis of the cag pathogenicity island in Helicobacter pylori isolates from patients with gastritis, peptic ulcer, and gastric cancerSteffen Backert
Department of Medical Microbiology, Otto von Guericke University, D 39120 Magdeburg, Germany
Infect Immun 72:1043-56. 2004..Here, we have compared cagPAI-dependent in vitro responses in H. pylori isolates obtained from 75 patients with gastritis, peptic ulcer, and gastric cancer (n = 25 in each group)...
Impaired production of gastric ghrelin in chronic gastritis associated with Helicobacter pyloriHiroyuki Osawa
Department of Internal Medicine, Division of Gastroenterology, Jichi Medical School, 3311 1 Yakushiji, Minamikawachi, Kawachi, Tochigi, Japan 329 0498
J Clin Endocrinol Metab 90:10-6. 2005..pylori-positive subjects. These findings suggest that impaired gastric ghrelin production in association with atrophic gastritis induced by H. pylori infection accounts for the decrease in plasma ghrelin concentration.
Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritisPeter Hofner
Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary
Helicobacter 12:124-31. 2007..The aim of this study was to evaluate the relationship between NOD1 and IL-8 genetic polymorphisms and the development of H. pylori-induced gastritis and duodenal ulcer (DU), as compared with TLR4 polymorphisms.
Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasiaTorsten K Roepke
Department of Pharmacology, Weill Medical College of Cornell University, New York, New York, United States of America
PLoS ONE 5:e11451. 2010..Kcne2(-/-) mice in a pathogen-free environment all exhibit a severe gastric preneoplastic phenotype comprising gastritis cystica profunda, 6-fold increased stomach mass, increased Ki67 and nuclear Cyclin D1 expression, and TFF2- and ..
Eosinophil infiltration, gastric juice and serum eosinophil cationic protein levels in Helicobacter pylori-associated chronic gastritis and gastric ulcerSelim A Aydemir
Department of Gastroenterology, Zonguldak Karaelmas University, Faculty of Medicine, Ic Hastaliklari ABD, Gastroenteroloji BD, 67800 Zonguldak, Turkey
Mediators Inflamm 13:369-72. 2004Helicobacter pylori is one of the main causes of gastroduodenal diseases, such as chronic gastritis and peptic ulcer. It has been shown that eosinophils increase in the stomach in H. pylori infection...
Frequency of vacA, cagA and babA2 virulence markers in Helicobacter pylori strains isolated from Mexican patients with chronic gastritisGloria Luz Paniagua
Universidad Nacional Autonoma de Mexico, Los Reyes Iztacala, Tlalnepantla, Estado de Mexico, Mexico
Ann Clin Microbiol Antimicrob 8:14. 2009Helicobacter pylori has been strongly associated with chronic gastritis, peptic and duodenal ulcers, and it is a risk factor for gastric cancer. Three major virulence factors of H...
Myocarditis presenting as gastritis in childrenYi-Jung Chang
Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tauyuan, Taiwan
Pediatr Emerg Care 22:439-40. 2006..associated with abdominal pain or vomiting remains a diagnostic challenge to physicians, it should be considered in the differential diagnosis of children with gastritis and hypotension or who are refractory to rehydration therapy.
Variation in serum pepsinogens with severity and topography of Helicobacter pylori-associated chronic gastritis in dyspeptic patients referred for endoscopyK Bodger
Division of Medicine, and Pathology Department, St James' University Hospital Beckett St, Leeds, UK
Helicobacter 6:216-24. 2001BACKGROUND: It has long been recognised that specific patterns of gastritis are linked with different gastroduodenal diseases and that serum pepsinogens vary with the histological state of the gastric mucosa...
Up-regulation of inducible nitric oxide synthase in Helicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal typeGabriele Rieder
Department of Surgery, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
Int J Med Microbiol 293:403-12. 2003..Several investigations on iNOS expression in H. pylori-associated gastritis have resulted in conflicting data. Therefore, we investigated the association between chronic H...
Red wine and green tea reduce H pylori- or VacA-induced gastritis in a mouse modelPaolo Ruggiero
Novartis Vaccines and Diagnostics s r l, Research Center, Via Fiorentina 1, Siena I 53100, Italy
World J Gastroenterol 13:349-54. 2007..To investigate whether red wine and green tea could exert anti-H pylori or anti-VacA activity in vivo in a mouse model of experimental infection...
Gastric acidity in patients with follicular gastritis is significantly reduced, but can be normalized after eradication for Helicobacter pyloriTomohiko Shimatani
Department of General Medicine, Hiroshima University Hospital, Hiroshima, Japan
Helicobacter 10:256-65. 2005Follicular gastritis is thought to be caused by Helicobacter pylori infection. However, the pathophysiology of it remains unclear.
Helicobacter pylori infection, histopathological gastritis and gastric epithelial cell apoptosis in childrenManisha Singh
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Acta Paediatr 95:732-7. 2006AIM: Features of gastritis and gastric epithelial cell apoptosis in children infected with Helicobacter pylori genotypes are seldom studied...
Influence of H pylori on plasma ghrelin in patients without atrophic gastritisMehmet Cindoruk
Gazi University, Department of Gastroenterology, Ankara, Turkey
World J Gastroenterol 13:1595-8. 2007To determine the association between H pylori infection and serum ghrelin levels in patients without atrophic gastritis.
Xanthogranulomatous gastritis with pseudosarcomatous changesHitoshi Kubosawa
Department of Pathology, Aoba Hospital, Chiba, Japan
Pathol Int 57:291-5. 2007..Although the precise pathogenesis could not be elucidated, recognition of this unusual morphological appearance is of importance to avoid an overdiagnosis of malignancy...
Dyspepsia in HIV-infected patients under highly active antiretroviral therapyAna Luiza Werneck-Silva
Casa da AIDS Infectious Disease Division, School of Medicine, University of Sao Paulo, Brazil
J Gastroenterol Hepatol 22:1712-6. 2007..We have done a prospective study of the prevalence and the etiology of endoscopic lesions in a large cohort of dyspeptic adult HIV-infected patients under HAART, according to their immunological status...
Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonographyYoshiaki Matsumoto
Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
J Gastroenterol 43:332-7. 2008..Few reports discuss gastric motility in relation to histologic gastritis. We examined the relation between gastric motility and histologic gastritis in Japanese patients with FD.
Low plasma ghrelin levels in patients with Helicobacter pylori-associated gastritisHajime Isomoto
Second Department of Internal Medicine, Atomic Bomb Disease Institute, Nagasaki University School of Medicine, Japan
Am J Med 117:429-32. 2004
Mutant p53 expression and apoptotic activity of Helicobacter pylori positive and negative gastritis in correlation with the presence of intestinal metaplasiaZsuzsa Unger
Semmelweis University, Faculty of Medicine, 2nd Department of Internal Medicine, 1088 Budapest, Szentkiralyi ut 46, Hungary
Eur J Gastroenterol Hepatol 15:389-93. 2003..We have studied the effect of H. pylori infection on apoptosis of the antral epithelium in the presence/absence of intestinal metaplasia and the expression of the p53 oncoprotein. The relationship between these two processes is analysed...
Adaptive cytoprotection through modulation of nitric oxide in ethanol-evoked gastritisJoshua Ka Shun Ko
School of Chinese Medicine, Hong Kong Baptist University, China
World J Gastroenterol 10:2503-8. 2004To assess the mechanisms of protective action by different mild irritants through maintenance of gastric mucosal integrity and modulation of mucosal nitric oxide (NO) in experimental gastritis rats.
MUC1 polymorphism confers increased risk for intestinal metaplasia in a Colombian population with chronic gastritisFilipe Silva
1Institute of Molecular Pathology and Immunology of the University of Porto, IPATIMUP, Porto, Portugal
Eur J Hum Genet 11:380-4. 2003..The aim of the present study was to evaluate MUC1 gene polymorphism in patients with chronic gastritis from Colombia. A Portuguese population of patients with chronic gastritis was used for comparative purposes...
Ulcers and gastritisM P Dore
Institute of Clinical Medicine, University of Sassari, Sassari, Italy
Endoscopy 36:42-7. 2004Significant advances continue to be made in the area of gastritis and ulcer disease...
Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinomaYana Zavros
Department of Gastroenterology, University of Michigan, Ann Arbor, MI 48109 0650, USA
Oncogene 24:2354-66. 2005The current study tests the hypothesis that chronic atrophic gastritis from hypochlorhydria in the gastrin-deficient mouse predisposes the stomach to gastric cancer...
Favourable effect of regular intake of fermented milk containing Lactobacillus johnsonii on Helicobacter pylori associated gastritisD Pantoflickova
Division of Gastroenterology, University Hospital, Lausanne, Switzerland
Aliment Pharmacol Ther 18:805-13. 2003..Fermented milk containing Lj1 (LC1), coadministered with antibiotics had a favourable effect on H. pylori gastritis. AIM: Evaluate the effect of LC1 intake without antibiotics on H. pylori gastritis. METHODS: Fifty H...
Gastrin (G) cells and somatostatin (D) cells in patients with dyspeptic symptoms: Helicobacter pylori associated and non-associated gastritisY Liu
Department of Pathology, Academic Medical Centre, University of Amsterdam, 1100 DD Amsterdam, The Netherlands
J Clin Pathol 58:927-31. 2005..Gastrin G cells and somatostatin D cells are important regulators of gastric acid secretion and alterations in their relative numbers may play a key role in gastroduodenal disease...
Focal-enhanced gastritis in regressive autism with features distinct from Crohn's and Helicobacter pylori gastritisFranco Torrente
The Centre for Paediatric Gastroenterology, Department of Histopathology, Royal Free and University College Medical School, London
Am J Gastroenterol 99:598-605. 2004BACKGROUND: Immunohistochemistry allowed recent recognition of a distinct focal gastritis in Crohn's disease...
Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphomaMario M D'Elios
Department of Internal Medicine, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
Microbes Infect 5:723-30. 2003..against CagA, is associated with peptic ulcer, whereas mixed Th1 and Th0 responses are present in non-ulcer gastritis. A deregulated H...
gammadelta T cells increase with gastric mucosal interleukin (IL)-7, IL-1beta, and Helicobacter pylori urease specific immunoglobulin levels via CCR2 upregulation in Helicobacter pylori gastritisSeiji Futagami
Third Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
J Gastroenterol Hepatol 21:32-40. 2006..The purpose of this study was to investigate possible factors that could impact on gammadelta T cell accumulation in the gastric mucosa...
Nodular gastritis in adults is caused by Helicobacter pylori infectionMasaki Miyamoto
First Department of Internal Medicine, Hiroshima University School of Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan
Dig Dis Sci 48:968-75. 2003A close relationship exists between nodular gastritis and Helicobacter pylori infection in children. The pathogenesis and optimal management of nodular gastritis in adults, however, are unclear...
Detection of Helicobacter pylori colonization in dental plaques and tongue scrapings of patients with chronic gastritisA Ozdemir
Department of Periodontology, , Etlik, Ankara, Turkey
Quintessence Int 32:131-4. 2001..were to detect the prevalence of Hp colonization in dental plaque and tongue scrapings of patients with chronic gastritis and to investigate the effect of systemic treatment upon this colonization and eradication of Hp from gastric ..
Experimental gastritis in mice enhances anxiety in a gender-related mannerE Painsipp
Research Unit of Translational Neurogastroenterology, Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitatsplatz 4, A 8010 Graz, Austria
Neuroscience 150:522-36. 2007..inflammation on the emotional-affective behavior is little known, we examined whether experimental gastritis modifies anxiety, stress coping and circulating corticosterone in male and female Him:OF1 mice...
Serum pepsinogen I, pepsinogen II, and gastrin 17 in relatives of gastric cancer patients: comparative study with type and severity of gastritisArghavan Haj-Sheykholeslami
Department of Gastroenterology, Digestive Disease Research Center, Shariati Hospital, Tehran, Iran
Clin Gastroenterol Hepatol 6:174-9. 2008..The aim of this study was to investigate the potential of biomarkers pepsinogen I (PGI), pepsinogen II (PGII), their ratio (PG I:II), as well as gastrin 17 for screening of precancerous conditions and corpus predominant gastritis.
Does Helicobacter pylori gastritis affect motor function of proximal stomach in dyspeptic patients?P J Van Der Schaar
Department of Gastroenterology Hepatology, Leiden University Medical Center, The Netherlands
Dig Dis Sci 46:1833-8. 2001..dyspepsia, no structural abnormalities found during endoscopy and biopsy-proven Helicobacter pylori-positive gastritis before and three months after Helicobacter pylori treatment...
Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non-steroidal anti-inflammatory drug useXiao Xing Li
Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China
PLoS ONE 4:e7985. 2009..Helicobacter pylori infection and non-steroidal anti-inflammatory drug (NSAID) use are two main contributors to gastritis and peptic ulcer...
Proinflammatory cytokine expression in gastric tissue from children with Helicobacter pylori-associated gastritisE Guiraldes
Departamentos de Pediatría y Anatomía Patológica, Pontificia Universidad Catolica de Chile, Santiago, Chile
J Pediatr Gastroenterol Nutr 33:127-32. 2001..The chronic inflammation that ensues involves the increased production of inflammatory cytokines. Published data on production of these mediators by gastric mucosa of H. pylori-infected children are few...
Effects of Helicobacter pylori infection on the expressions of Bax and Bcl-2 in patients with chronic gastritis and gastric cancerWaldemar Bartchewsky
Unidade Integrada de Farmacologia e Gastroenterologia, Universidade São Francisco, Av São Francisco de Assis, 218 Jd São José, Braganca Paulista, SP, Brazil
Dig Dis Sci 55:111-6. 2010..evaluate the influence of Helicobacter pylori on Bax and Bcl-2 mRNA and protein levels in patients with chronic gastritis and gastric cancer...
Molecular typing of Campylobacter jejuni and C. coli from chickens and patients with gastritis or Guillain-Barré syndrome based on multilocus sequence types and pulsed-field gel electrophoresis patternsShizuka Yabe
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata 951 8510, Japan
Microbiol Immunol 54:362-7. 2010..C. coli from enteritis was also divergent. Novel ST types may represent unidentified native clones in each country. Pulsed-field gel electrophoresis confirmed the above typing and demonstrated long-term persistence and transmission...
Therapeutic effect of Streptococcus thermophilus CRL 1190-fermented milk on chronic gastritisCecilia Rodriguez
Centro de Referencia para Lactobacilos CERELA CONICET, Chacabuco 145, San Miguel de Tucuman, 4000, Tucuman, Argentina
World J Gastroenterol 16:1622-30. 2010To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice.
Gastric neuroendocrine carcinoma associated with atrophic gastritis in the norwegian lundehundG Qvigstad
Department of Gastroenterology and Hepatology, St Olav s Hospital, Trondheim University Hospital, N 7006 Trondheim
J Comp Pathol 139:194-201. 2008In humans and rodents the association between atrophic gastritis, hypergastrinemia and gastric neoplasia is well-documented...
The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in miceK A Eaton
Department of Veterinary Biosciences, Ohio State University, Columbus, OH 43210, USA
J Immunol 166:7456-61. 2001b>Gastritis due to Helicobacter pylori in mice and humans is considered a Th1-mediated disease, but the specific cell subsets and cytokines involved are still not well understood...
Pathogenic effector T cell enrichment overcomes regulatory T cell control and generates autoimmune gastritisJoao P Monteiro
Divisão de Medicina Experimental, Coordenação de Pesquisa, Instituto Nacional de Cancer, Rio de Janeiro, Brazil
J Immunol 181:5895-903. 2008..Postneonatal thymectomy autoimmune gastritis has also been attributed to the absence of Tregs...
Overexpression of p73 as a tissue marker for high-risk gastritisGonzalo Carrasco
Department of Anatomic Pathology, Pontificia Universidad Catolica de Chile, Santiago, Chile
Clin Cancer Res 16:3253-9. 2010Histologic assessment of high-risk gastritis for the development of gastric cancer is not well defined. The identification of tissue markers together with the integration of histologic features will be required for this assessment.
Gastritis and gastric cancer. Western countriesP Sipponen
Department of Pathology, Jorvi Hospital, Espoo, Finland
Gastroenterol Clin North Am 29:579-92, v-vi. 2000Helicobacter pylori infection is the cause of chronic gastritis that progresses to atrophic gastritis over years and decades in more than half of affected individuals. H...
Prevention of chronic gastritis by fermented milks made with exopolysaccharide-producing Streptococcus thermophilus strainsC Rodriguez
Centro de Referencia para Lactobacilos CONICET, Chacabuco 145, San Miguel de Tucuman, 4000 Tucuman, Argentina
J Dairy Sci 92:2423-34. 2009Acetyl-salicylic acid (ASA) is a nonsteroidal antiinflammatory/analgesic drug, which may cause gastritis or stomach ulcers if intensively employed...
Characterization of multiple Helicobacter bizzozeronii isolates from a Finnish patient with severe dyspeptic symptoms and chronic active gastritisRauni Kivistö
Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
Helicobacter 15:58-66. 2010Helicobacter pylori is the primary cause of gastritis and peptic ulceration in humans...
Bioinformatics research on chronic superficial gastritis of Pi-deficiency syndrome by gene arraysYu Long Chen
Pi Wei Institute, Guangzhou University of Chinese Medicine, Guangzhou, China
Chin J Integr Med 15:341-6. 2009..the bioinformatical characteristics of differential gene expression in patients with chronic superficial gastritis (CSG) with the Pi-deficiency syndrome (PDS) and those of the non-Pi-deficiency syndrome (non-PDS), i.e...
Murine splenocytes induce severe gastritis and delayed-type hypersensitivity and suppress bacterial colonization in Helicobacter pylori-infected SCID miceK A Eaton
Department of Veterinary Biosciences, Ohio State University, Columbus, Ohio 43210, USA
Infect Immun 67:4594-602. 1999The goal of this study was to evaluate the role of host immunity in gastritis and epithelial damage due to Helicobacter pylori. Splenocytes from H. pylori-infected and uninfected C57BL/6 mice were adoptively transferred to H...
Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritisDinorah N Martínez-Carrillo
Laboratorio de Investigación Clínica, Unidad Académica de Ciencias Químico Biológicas, Universidad Autonoma de Guerrero, Av, Lázaro Cárdenas S N, Ciudad Universitaria, Colonia Haciendita, Chilpancingo, Guerrero, C, P, 39090, Mexico
BMC Gastroenterol 10:126. 2010..Our objective was to determine if the IL-1B -511 T>C and -31 C>T polymorphisms and H. pylori vacA genotypes are associated with risk of chronic gastritis and gastric ulcer in a Mexican population.
Isocitrate dehydrogenase of Helicobacter pylori potentially induces humoral immune response in subjects with peptic ulcer disease and gastritisM Abid Hussain
Pathogen Evolution Laboratory, Centre for DNA Fingerprinting and Diagnostics CDFD, Hyderabad, India
PLoS ONE 3:e1481. 2008H. pylori causes gastritis and peptic ulcers and is a risk factor for the development of gastric carcinoma...
Helicobacter pylori and gastritis: Untangling a complex relationship 27 years onVictoria P Y Tan
Department of Medicine, University of Hong Kong, China
J Gastroenterol Hepatol 26:42-5. 2011..Helicobacter pylori (HP) has become the linchpin in our understanding of important gastric conditions including gastritis, intestinal metaplasia (IM), gastric/duodenal ulcers (GU/DU), Mucosal Associated Lymphoid Tumour (MALToma) and ..
OLGA gastritis staging in young adults and country-specific gastric cancer riskMassimo Rugge
Department of Medical Diagnostic Sciences and Special Therapies II Pathology Unit, University of Padova, Italy
Int J Surg Pathol 16:150-4. 2008Geographical differences have been shown in the clinical outcomes of Helicobacter pylori-associated gastritis phenotypes and in gastric cancer risk...
A major linkage region on distal chromosome 4 confers susceptibility to mouse autoimmune gastritisP A Silveira
Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Australia
J Immunol 162:5106-11. 1999Although much is known about the pathology of human chronic atrophic (type A, autoimmune) gastritis, its cause is poorly understood...
[The low prevalence of Helicobacter pylori gastritis in newly diagnosed inflammatory bowel disease children and adolescent]Małgorzata Sładek
Klinika Pediatrii, Gastroenterologii i Zywienia, Uniwersytetu Jagiellonskiego, Collegium Medicum w Krakowie
Przegl Lek 64:65-7. 2007Data concerning prevalence rate of Helicobacter pylori gastritis in inflammatory bowel disease (IBD) patients is conflicting...
Distinct patterns of chronic gastritis associated with carcinoid and cancer and their role in tumorigenesisE Solcia
Department of Human Pathology and Genetics, I Medical Faculty, University of Pavia, Italy
Yale J Biol Med 65:793-804; discussion 827-9. 1992..argyrophil carcinoids, of which 23 arose in a background of hypergastrinemia and type A chronic atrophic gastritis (A-CAG), mainly with histologic patterns suggestive of an autoimmune process...
Symptom score does not correlate with gastritis grade and Helicobacter pylori infection in non ulcer dyspepsiaA Joshi
All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Trop Gastroenterol 22:194-6. 2001..In NUD patients positive for H. pylori, there is a significant increase in the severity of gastritis both in the antrum and the body.
Analysis of iceA genotypes in South African Helicobacter pylori strains and relationship to clinically significant diseaseM Kidd
GI Clinic and Department of Medicine, University of Cape Town and Groote Schuur Hospital, South Africa
Gut 49:629-35. 2001..30 with peptic ulcer disease (PUD), 19 with distal gastric adenocarcinoma (GC), and 37 with non-erosive gastritis) for the presence of iceA1 or iceA2 genes, and for differences in the genetic organisation of iceA2 by ..
Expression of the gastric H/K-ATPase alpha-subunit in the thymus may explain the dominant role of the beta-subunit in the pathogenesis of autoimmune gastritisF Alderuccio
Department of Pathology and Immunology, Monash University Medical School, Alfred Hospital, Melbourne, Australia
Autoimmunity 25:167-75. 1997..beta-subunit, are the major targets of parietal cell autoantibodies associated with human and murine autoimmune gastritis. The murine disease induced by neonatal thymectomy is T cell-mediated...
Helicobacter pylori outer membrane proteins and gastroduodenal diseaseY Yamaoka
Department of Medicine, Michael E DeBakey Veterans Affairs Medical Center 111D, Houston, TX 77030, USA
Gut 55:775-81. 2006..A number of Helicobacter pylori outer membrane proteins (OMPs) undergo phase variations. This study examined the relation between OMP phase variations and clinical outcome...
[Chronic gastritis: last decade's achievements and problems]S I Pimanov
Klin Med (Mosk) 83:54-8. 2005Classifications of chronic gastritis and neoplastic gastric diseases, developed in recent years (1996 Houston update of 1990 Sidney classification system, 2002 New Orlean classification of atrophic gastritis according to recommendations ..
The role of persistence in Helicobacter pylori pathogenesisDawn A Israel
Division of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-0252, USA
Curr Opin Gastroenterol 22:3-7. 2006PURPOSE OF REVIEW: Helicobacter pylori induces chronic gastritis and is the strongest known risk factor for peptic ulcer disease and distal gastric cancer, yet only a fraction of colonized individuals ever develop clinical disease...
Evolution of gastritis in patients with gastric erosionsKari T Toljamo
Department of Internal Medicine, Division of Gastroenterology, University of Oulu, Finland
Scand J Gastroenterol 40:1275-83. 2005Gastric erosions are mainly associated with Helicobacter pylori infection and non-steroidal anti-inflammatory drugs (NSAIDs), but there has been no information available on the long-term evolution of gastritis in subjects with erosions.
[Comparative study between rapid urease test, imprint and histopathological study for Helicobacter pylori diagnosis]Oscar Aguilar-Soto
Servicio de Cirugia Experimental, Unidad de Enseñanza e Investigación Biomédica, Servicio de Endoscopia Gastrointestinal, Centro Medico Nacional 20 de Noviembre, ISSSTE
Rev Gastroenterol Mex 69:136-42. 2004..Endoscopic findings included gastritis (87.50%), pangastritis (2.30%) and another diagnoses (10.22%)...
Histology and culture results among subjects with antibodies to CagA but no evidence of Helicobacter pylori infection with IgG ELISAWeimin Ye
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Scand J Gastroenterol 40:312-8. 2005..In a recent case-control study, this serological pattern was strongly linked to stomach cancer, and it was hypothesized to represent "burned-out" CagA-positive infections. The aim of this analysis was to test this hypothesis...
Effect of Helicobacter pylori infection on gastric mucosal pathologic change and level of nitric oxide and nitric oxide synthaseYong Fu Wang
First Hospital, Baotou Medical College, University of Science and Technology of Inner Mongolia, Baotou 014010, Inner Mongolia, China
World J Gastroenterol 11:5029-31. 2005....
Influence of bile reflux and Helicobacter pylori infection on gastritis in the remnant gastric mucosa after distal gastrectomyHisanori Abe
Arita Gastro-Intestinal Hospital, 1-2-6 Maki, Oita, 870-0924, Japan
J Gastroenterol 40:563-9. 2005..been identified in the remnant stomach, but it is still unclear which factor is important in the pathogenesis of gastritis in the remnant stomach after distal gastrectomy...
Helicobacter pylori: present status and future prospects in JapanHidekazu Suzuki
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
J Gastroenterol 42:1-15. 2007..We should consider such provocative scientific ideas as bridges to the future disease control...
Research progress on Helicobacter pylori outer membrane proteinShi he Shao
Department of Medical Microbiology and Parasitology, Medical Technology College, Jiangsu University, Zhenjiang 212001, Jiangsu Province, China
World J Gastroenterol 11:3011-3. 2005..They are significantly associated with high H pylori density, the damage of gastric mucosa, high mucosal IL-8 levels and severe neutrophil infiltration. We introduce their research progress on pathogenicity...
Regular arrangement of collecting venules (RAC): a characteristic endoscopic feature of Helicobacter pylori-negative normal stomach and its relationship with esophago-gastric adenocarcinomaKazuyoshi Yagi
Department of Internal Medicine, Niigata Prefectural Yoshida Hospital, Yoshida-machi, Niigata, 959-0242, Japan
J Gastroenterol 40:443-52. 2005
Topographic expression of MUC5AC and MUC6 in the gastric mucosa infected by Helicobacter pylori and in associated diseasesTerezinha Marques
Department of Pathology, Medical School, Federal University of Minas Gerais UFMG, Brazil
Pathol Res Pract 201:665-72. 2005..The immunoexpression of MUC5AC and MUC6 was evaluated in 75 adults presenting Helicobacter pylori gastritis (n = 22; 11 cagA positive), duodenal ulcer (DU, n = 11), gastric ulcer (GU, n = 9), gastric carcinoma (GC, n = ..
[Histopathological study of gastric polyps. A report of 65 cases]Faten Farah Klibi
, Tunisie
Tunis Med 84:611-6. 2006..within the polyps or into the surrounding gastric mucosa, such as intestinal metaplasia and Helicobacter Pylori gastritis. This work allowed us to recommend complete removal of gastric polyps and the realization of biopsies of the ..
Detection of Helicobacter pylori DNA in peripheral blood from patients with peptic ulcer or gastritisYan Huang
Department of Infectious Diseases, Xiangya Hospital, Central South University, Hunan, PR China
APMIS 114:851-6. 2006..pylori DNA in peripheral blood and gastric mucosa of patients with peptic ulcer or chronic gastritis by polymerase chain reaction (PCR). We found H...
Expression of mutant type-p53 products in H pylori-associated chronic gastritisMasaaki Kodama
Department of Gastroenterology, Oita University, Hasama machi, Oita, 879 5593, Japan
World J Gastroenterol 13:1541-6. 2007..To investigate the mutation of p53 immunohistochemically in non-tumorous gastric mucosa with H pylori infection before and after H pylori eradication therapy...
TNF-alpha-inducing protein, a carcinogenic factor secreted from H. pylori, enters gastric cancer cellsMasami Suganuma
Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan
Int J Cancer 123:117-22. 2008..pylori from patients with chronic gastritis, suggesting that Tip alpha is an essential factor in H...
[Biochemical and immunological criteria for evaluation of gastric mucosa in tumor and non-tumor pathology]M N Uspenskiĭ
Vopr Onkol 53:304-10. 2007
Helicobacter pylori and Helicobacter heilmannii in untreated Bulgarian children over a period of 10 yearsLyudmila Boyanova
Department of Microbiology, Medical University of Sofia, Zdrave Street 2, 1431 Sofia, Bulgaria
J Med Microbiol 56:1081-5. 2007..pylori density in specimens by culture. Antral specimens from children with chronic gastritis (n=513), peptic ulcers (n=54) and other diseases (n=91) were evaluated by direct Gram staining (DGS), in-house ..
Impact of Helicobacter pylori infection on the humoral immune response to MUC1 peptide in patients with chronic gastric diseases and gastric cancerK Klaamas
National Institute for Health Development, Tallinn, Estonia
Immunol Invest 36:371-86. 2007..The findings suggest that, in some individuals, the H. pylori infection may stimulate immune response to tumor-associated MUC1 peptide antigen thus modulating tumor immunity...
[Inflammation as a basis for Helicobacter pylori-associated diseases]A V Kononov
Arkh Patol 68:3-10. 2006..Chronic gastritis is considered as the morphological basis of gastric ulcer and non-cardial cancer of the stomach of intestinal ..
Gastric angiogenesis and Helicobacter pylori infectionI D Pousa
Service of Gastroenterology, Hospital Universitario de la Princesa, Madrid, Spain
Rev Esp Enferm Dig 98:527-41. 2006..pylori) infection, including gastritis, peptic ulcer, and gastric carcinoma, prompts consideration of a potential relationship between mucosal ..
[Helicobacter pylori 2006: how to test, when to treat]B van der Weg
Fachbereich Gastroenterologie/Hepatologie, Kantonsspital St. Gallen
Schweiz Rundsch Med Prax 95:1413-8. 2006..pylori eradication consists of a proton pump inhibitor (PPI) and two antibiotics, though it isn't always successful. After a second treatment failure, a H. pylori culture is indicated to asses the antibiotic resistances...
[Gastric pseudolipomatosis: an under-diagnosed entity]C Alvarez-Alvarez
Gastroenterol Hepatol 28:659. 2005
Expression of Lewis antigens and their precursors in gastric mucosa: relationship with Helicobacter pylori infection and gastric carcinogenesisH S Lee
Department of Pathology, Seoul National University College of Medicine, Korea
J Pathol 209:88-94. 2006..Expression was also investigated in gastric tissues showing chronic gastritis, intestinal metaplasia, and carcinoma from 42 patients with gastric cancer...
Evaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adultsTomoari Kamada
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan
J Gastroenterol Hepatol 21:258-61. 2006Many studies have shown that Helicobacter pylori infection is associated with chronic gastritis, peptic ulcers and gastric carcinoma in adults. However, little is known about these associations in the younger population...
Increased epithelial and serum expression of macrophage migration inhibitory factor (MIF) in gastric cancer: potential role of MIF in gastric carcinogenesisX-X He
Department of Gastroenterology, The Second Affiliated Hospital of Guanzhou Medical College, Guangzhou, China
Gut 55:797-802. 2006..MATERIALS AND METHODS: Patients with a normal gastric mucosa, Helicobacter pylori infected gastritis, intestinal metaplasia, and gastric adenocarcinoma were included...
Comparative immunoproteomics of identification and characterization of virulence factors from Helicobacter pylori related to gastric cancerYu-Fen Lin
Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Mol Cell Proteomics 5:1484-96. 2006..2%, n = 95) compared with 30.9% for gastritis (n = 94) and 35.5% for DU (n = 124)...
Response of IgG1 and IgG2 subclasses to Helicobacter pylori in subjects with chronic inflammation of the gastric mucosa, atrophy and gastric cancer in a country with high Helicobacter pylori infection prevalenceTamara Vorobjova
Centre of Molecular and Clinical Medicine, Institute of General and Molecular Pathology, University of Tartu, Tartu, Estonia
APMIS 114:372-80. 2006..Helicobacter pylori IgG level was lower in atrophic gastritis compared with nonatrophic gastritis (chronic inflammation) (p=0.001)...
Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardiaYasuo Egi
Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
Jpn J Clin Oncol 37:365-9. 2007Helicobacter pylori-induced gastritis is an important factor for gastric carcinogenesis. However, it is still controversial whether it is also applicable for cardiac cancer development. Recently, we reported that H...
Gastric precancerous changes: carcinogenesis, clinical behaviour immunophenotype study and surveillanceG Testino
Unit of Hepatogastroenterology, Department of Organ Transplantation, S Martino Hospital, Genoa, Italy
Panminerva Med 48:109-18. 2006..with noninvasive (formerly dysplasia) or invasive neoplastic modifications solely develop by means of chronic gastritis with its atrophic evolution and achlorhydria...
Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progressionC B Jackson
Gastrointestinal Cancer Lab, Department of Medicine, The University of Melbourne at Western Hospital, Footscray, 3011, Melbourne, Australia
J Pathol 213:140-51. 2007..of oncogenic STAT3 after altered SHP-2 : ERK1/2 signalling produces dysplastic antral tumours preceded by gastritis and metaplasia. In a cohort of patient gastric biopsies with known H...
Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancerToru Hiyama
Health Service Center, Hiroshima University, Higashihiroshima 739 8521, Japan
Int J Mol Med 12:169-74. 2003..carcinogenesis, we examined mtDNA mutations in gastric cancers and in Helicobacter pylori-associated chronic gastritis (H. pylori-CG), which is associated with an increased risk for gastric cancer development...
Reg protein is a unique growth factor of gastric mucosal cellsYoshikazu Kinoshita
Department of Gastroenterology and Hepatology, Shimane University, School of Medicine, 89-1 Enya-cho, 693-8501, Izumo, Japan
J Gastroenterol 39:507-13. 2004..In summary, Reg protein may be a growth factor that regulates the proliferation and differentiation of normal and neoplastic gastric epithelial cells...
Helicobacter pylori babA2, cagA, and s1 vacA genes work synergistically in causing intestinal metaplasiaC-F Zambon
Department of Medical and Surgical Sciences, University-Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
J Clin Pathol 56:287-91. 2003..In addition, to verify whether these genes work synergistically or independently in causing gastritis, peptic ulcer, and intestinal metaplasia...
Presence of iceA1 but not cagA, cagC, cagE, cagF, cagN, cagT, or orf13 genes of Helicobacter pylori is associated with more severe gastric inflammation in TaiwaneseShew-Meei Sheu
Department of Microbiology and Immunology, National Cheng Kung University Medical College, Tainan, Taiwan
J Formos Med Assoc 101:18-23. 2002..In contrast, bacterial factors such as the presence of iceAl could be related to severity of gastric inflammation and increase in ulcer size in H. pylori-infected patients...
Role of Helicobacter pylori CagA+ infection in determining oxidative DNA damage in gastric mucosaA Papa
Institute of Internal Medicine, Giovanni XXIII Cancer Research Center and Institute of General Pathology, Institute of Pathology, Catholic University of Rome, Italy
Scand J Gastroenterol 37:409-13. 2002..pylori status and cytotoxic associated gene product A (CagA); 2) to determine the relationship between ROS generation and amount of 8-OHdG...
Inducible nitric oxide synthase expression in gastroduodenal diseases infected with Helicobacter pyloriH J Son
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Helicobacter 6:37-43. 2001..gastric cancer, 12 patients with gastric ulcer, 18 patients with duodenal ulcer and 26 patients with chronic gastritis, were enrolled in this study...
Helicobacter pylori infection and oncogene expressions in gastric carcinoma and its precursor lesionsJie Wang
Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-1709, USA
Dig Dis Sci 47:107-13. 2002..H. pylori infection was found in all cases of chronic gastritis, atrophic gastritis, intestinal metaplasia, and early gastric carcinoma, and in 16 of 30 (53%) cases of advanced ..
Research Grants
- UREASE AND GENE EXPRESSION IN CAMPYLOBACTER PYLORIHARRY MOBLEY; Fiscal Year: 1991..pylori, a spiral-shaped gram-negative microaerophilic rod, is not postulated to be an etiological agent of gastritis and peptic ulcer disease...
- UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORIHARRY MOBLEY; Fiscal Year: 2007..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
- Prophylactic and Therapeutic Immunization against H. pylori in Rhesus MacaquesJAY SOLNICK; Fiscal Year: 2007Helicobacter pylori commonly infects the human stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some...
- EFFECTS OF DIETARY POLYUNSATURATED FAT ON HELICOBACTER PYLORIDuane Smoot; Fiscal Year: 2000Helicobacter pylori (H. pylori) infection is the most common cause of chronic gastritis in man, and it has been implicated as an etiological factor in the development of peptic ulcer disease...
- UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORIHARRY MOBLEY; Fiscal Year: 2003..a gram-negative, microaerophilic spiral-shaped bacterium is the most frequently cited etiologic agent of human gastritis and peptic ulceration...
- Modulation of Outer Membrane Protein Expressin in Helicobacter pyloriJAY SOLNICK; Fiscal Year: 2009Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some. H...
- BACTERIAL INDUCED COLITIS IN HLA-B27 RATSLEVINUS DIELEMAN; Fiscal Year: 2002..Our hypothesis is that chronic colitis and gastritis is the result of an overly aggressive immune response to luminal bacteria in a genetically susceptible host...
- Modulation of Outer Membrane Protein Expressin in Helicobacter pyloriJay V Solnick; Fiscal Year: 2010Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some. H...
- Modulation of Outer Membrane Protein Expressin in Helicobacter pyloriJAY SOLNICK; Fiscal Year: 2009Helicobacter pylori commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some. H...
- Acetone metabolism in Helicobacter pyloriTimothy Hoover; Fiscal Year: 2004..human pathogen that colonizes the gastric mucosa, leading to gastric inflammation that can progress to chronic gastritis, peptic ulcer, gastric cancer or mucosal-associated lymphoma. The ability of H...
- MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDESMICHAEL TRENT; Fiscal Year: 2006..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
- H.pylori arginase modulation of ulcers and cancerDavid McGee; Fiscal Year: 2007Helicobacter pylori infects approximately 50% of the human population, causing severe gastric diseases including gastritis, peptic ulcers, and gastric cancer. H...
- Oxidative Injury to Gastric Epithelial Cells by H. pyloriSheila Crowe; Fiscal Year: 2009Helicobacter pylori causes gastritis, peptic ulcer disease, gastric carcinoma, and gastric lymphoma, however, only a subset of infected individuals develops disease in the form of ulceration or adenocarcinoma...
- Oxidative Injury to Gastric Epithelial Cells by H. pyloriSheila E Crowe; Fiscal Year: 2010Helicobacter pylori causes gastritis, peptic ulcer disease, gastric carcinoma, and gastric lymphoma, however, only a subset of infected individuals develops disease in the form of ulceration or adenocarcinoma...
- Risk factors for gastric disease in pediatric H. pyloriBenjamin Gold; Fiscal Year: 2006Helicobacter pylori (Hp) is a major cause of chronic-active gastritis, primary duodenal ulcers and strongly linked to gastric cancer. Most Hp infections worldwide are acquired in childhood...
- MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDESMICHAEL TRENT; Fiscal Year: 2007..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
- MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDESMICHAEL TRENT; Fiscal Year: 2009..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
- MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDESMICHAEL STEPHEN TRENT; Fiscal Year: 2010..The organism has been classified as a class I carcinogen and plays a major etiological role in human gastritis, peptic ulcer disease, and gastric carcinoma. Humans are the only significant reservoir for H...
- H. PYLORI INFECTION AND GI DISEASE IN ALASKA NATIVESDouglas Berg; Fiscal Year: 2003..It is the major cause of severe gastritis and peptic ulcers, and a risk factor for gastric cancer, although most infections are asymptomatic...
- IN VIVO PATHOGENESIS OF HELICOBACTER PYLORIJames Fox; Fiscal Year: 2009..Clinical and epidemiologic studies suggest that the development of atrophic gastritis intestinal metaplasia and dysplasia represent essential steps in the cascade of events leading to gastric cancer...
- A Novel In-Vivo Capsule Camera with High Resolution Optically Unwarpped 360-DegreJason Geng; Fiscal Year: 2007..g. hiatal hernia, gastritis, ulcers, polyps, stomach/colon cancer...
