acute cholecystitis

Summary

Summary: Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.

Top Publications

  1. ncbi Randomized clinical trial of open versus laparoscopic cholecystectomy in the treatment of acute cholecystitis (Br J Surg 2005; 92: 44-49)
    R Rai
    Br J Surg 92:494. 2005
  2. pmc Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines
    Masahiko Hirota
    Department of Gastroenterological Surgery, Kumamoto University Graduate School of Medical Sciences, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
    J Hepatobiliary Pancreat Surg 14:78-82. 2007
  3. ncbi EUS-guided transmural cholecystostomy as rescue management for acute cholecystitis in elderly or high-risk patients: a prospective feasibility study
    Sang Soo Lee
    Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
    Gastrointest Endosc 66:1008-12. 2007
  4. doi Endoscopic gallbladder drainage for management of acute cholecystitis
    Takao Itoi
    Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan
    Gastrointest Endosc 71:1038-45. 2010
  5. doi Does an acute care surgical model improve the management and outcome of acute cholecystitis?
    Christopher W Lehane
    Department of General Surgery, Prince of Wales Hospital and University of New South Wales, Sydney, Australia
    ANZ J Surg 80:438-42. 2010
  6. doi Impact of delayed laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for patients with complicated acute cholecystitis
    Hyung Ook Kim
    Department of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Surg Laparosc Endosc Percutan Tech 19:20-4. 2009
  7. doi Gallbladder carcinoma manifesting as acute cholecystitis: clinical and computed tomographic features
    Jiun Lung Liang
    Department of Radiology, Chang Gung University, College of Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Kaohsiung, Taiwan
    Surgery 146:861-8. 2009
  8. ncbi Laparoscopic cholecystectomy for acute cholecystitis. Can preoperative factors predict conversion?
    Iftikhar A Khan
    Division of General Surgery, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia
    Saudi Med J 25:299-302. 2004
  9. ncbi Role of laparoscopic cholecystectomy in the early management of acute gallbladder disease
    W K Peng
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, Little France Crescent, Edinburgh EH16 4SA, UK
    Br J Surg 92:586-91. 2005
  10. ncbi Microflora of bile aspirates in patients with acute cholecystitis with or without cholelithiasis: a tropical experience
    Malini R Capoor
    Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India
    Braz J Infect Dis 12:222-5. 2008

Research Grants

  1. MYOGENIC DISORDERS OF THE GALLBLADDER
    Jose Behar; Fiscal Year: 2004
  2. GALLBLADDER MUSCARINIC RECEPTORS IN ACUTE CHOLECYSTITIS
    Stuart Myers; Fiscal Year: 2001
  3. INJURY TO LIVER SINUSOIDAL ENDOTHELIAL CELLS
    Steven Strasberg; Fiscal Year: 2003

Detail Information

Publications195 found, 100 shown here

  1. ncbi Randomized clinical trial of open versus laparoscopic cholecystectomy in the treatment of acute cholecystitis (Br J Surg 2005; 92: 44-49)
    R Rai
    Br J Surg 92:494. 2005
  2. pmc Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines
    Masahiko Hirota
    Department of Gastroenterological Surgery, Kumamoto University Graduate School of Medical Sciences, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
    J Hepatobiliary Pancreat Surg 14:78-82. 2007
    The aim of this article is to propose new criteria for the diagnosis and severity assessment of acute cholecystitis, based on a systematic review of the literature and a consensus of experts...
  3. ncbi EUS-guided transmural cholecystostomy as rescue management for acute cholecystitis in elderly or high-risk patients: a prospective feasibility study
    Sang Soo Lee
    Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
    Gastrointest Endosc 66:1008-12. 2007
    Although EUS-guided drainage procedures have been used to collect peripancreatic fluids, little is known regarding EUS-guided transmural gallbladder drainage for high-risk patients with acute cholecystitis.
  4. doi Endoscopic gallbladder drainage for management of acute cholecystitis
    Takao Itoi
    Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan
    Gastrointest Endosc 71:1038-45. 2010
    Nonoperative gallbladder drainage methods for acute cholecystitis include percutaneous transhepatic gallbladder drainage and percutaneous transhepatic gallbladder aspiration, endoscopic nasogallbladder drainage and gallbladder stenting ..
  5. doi Does an acute care surgical model improve the management and outcome of acute cholecystitis?
    Christopher W Lehane
    Department of General Surgery, Prince of Wales Hospital and University of New South Wales, Sydney, Australia
    ANZ J Surg 80:438-42. 2010
    The aim of this study was to compare the management and outcome of acute cholecystitis in an acute care surgery (ACS) model to that of the traditional home-call attending surgeon...
  6. doi Impact of delayed laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for patients with complicated acute cholecystitis
    Hyung Ook Kim
    Department of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Surg Laparosc Endosc Percutan Tech 19:20-4. 2009
    Laparoscopic cholecystectomy (LC) for complicated acute cholecystitis is associated with high rates of complications and conversion to open cholecystectomy...
  7. doi Gallbladder carcinoma manifesting as acute cholecystitis: clinical and computed tomographic features
    Jiun Lung Liang
    Department of Radiology, Chang Gung University, College of Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Kaohsiung, Taiwan
    Surgery 146:861-8. 2009
    Gallbladder carcinoma is uncommon and may manifest as acute cholecystitis. An accurate diagnosis is helpful for operative planning and this study attempted to explore the distinctive clinical and computed tomographic (CT) features for ..
  8. ncbi Laparoscopic cholecystectomy for acute cholecystitis. Can preoperative factors predict conversion?
    Iftikhar A Khan
    Division of General Surgery, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia
    Saudi Med J 25:299-302. 2004
    To determine if preoperative clinical, laboratory and radiology data can predict conversion of laparoscopic cholecystectomy for acute cholecystitis to open procedure.
  9. ncbi Role of laparoscopic cholecystectomy in the early management of acute gallbladder disease
    W K Peng
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, Little France Crescent, Edinburgh EH16 4SA, UK
    Br J Surg 92:586-91. 2005
    ..This study evaluated the role of laparoscopic surgery in the early management of acute gallbladder disease in a single large UK teaching hospital...
  10. ncbi Microflora of bile aspirates in patients with acute cholecystitis with or without cholelithiasis: a tropical experience
    Malini R Capoor
    Department of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India
    Braz J Infect Dis 12:222-5. 2008
    ..The patients were divided into three groups: Group A consisted of patients with acute cholecystitis with cholelithiasis; Group B consisted of patients with acute cholecystitis with gastrointestinal ailments ..
  11. ncbi Latent gallbladder carcinoma in a young adult patient with acute cholecystitis: report of a case
    Shogo Tanaka
    Department of Surgery, Moriguchi Ikuno Memorial Hospital, 6 17 33 Satanakamachi, Moriguchi, Osaka 570 0002, Japan
    Surg Today 37:713-5. 2007
    b>Acute cholecystitis associated with gallbladder carcinoma is very rare in young patients (younger than 30 years of age). Moreover, a definitive preoperative diagnosis is difficult...
  12. ncbi Right bundle branch block and coved-type ST-segment elevation mimicked by acute cholecystitis
    Masato Furuhashi
    Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
    Circ J 67:802-4. 2003
    A 69-year-old woman had acute cholecystitis that mimicked right bundle branch block with coved-type ST-segment elevation in the precordial electrocardiogram leads (Brugada-type ST shift)...
  13. pmc Techniques of biliary drainage for acute cholecystitis: Tokyo Guidelines
    Toshio Tsuyuguchi
    Department of Medicine and Clinical Oncology, Graduate School of Medicine Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8677, Japan
    J Hepatobiliary Pancreat Surg 14:46-51. 2007
    The principal management of acute cholecystitis is early cholecystectomy. However, percutaneous transhepatic gallbladder drainage (PTGBD) may be preferable for patients with moderate (grade II) or severe (grade III) acute cholecystitis...
  14. pmc Acute cholecystitis accompanied by acute pancreatitis potentially caused by Dolosigranulum pigrum
    Jung Chung Lin
    Division of Infectious Diseases and Tropical Medicine, Tri Service General Hospital, National Defence Medical Center, Taipei, Taiwan, Republic of China
    J Clin Microbiol 44:2298-9. 2006
    We report a case of acute cholecystitis accompanied by acute pancreatitis and caused by Dolosigranulum pigrum in a 76-year-old male with gallstones. D...
  15. ncbi Laparoscopic cholecystectomy for acute cholecystitis in the elderly: a retrospective study of 100 patients
    J Moyson
    Department of Digestive, Laparoscopic and Thoracic Surgery C H U Brugmann, U L B, Brussels, Belgium
    Hepatogastroenterology 55:1975-80. 2008
    The objective of this retrospective study is to evaluate the use oflaparoscopic cholecystectomy in the treatment of acute cholecystitis in elderly patients, and to identify risk factors for mortality.
  16. ncbi Increased gallbladder trypsin in acute cholecystitis indicates functional disorder in the sphincter of oddi and could make EPT a logical procedure
    Jozef Vracko
    University Medical Center, Ljubljana, Slovenia
    Surg Laparosc Endosc Percutan Tech 13:308-13. 2003
    Clinical and surgical observations confirm that acute cholecystitis (ACh) and acute biliary pancreatitis can coexist and that differentiation may be difficult even at surgery...
  17. ncbi Acute cholecystitis: MR findings and differentiation from chronic cholecystitis
    Ersan Altun
    Department of Radiology, University of North Carolina at Chapel Hill, Campus Box 7510, 2000 Old Clinic Bldg, Chapel Hill, NC 27599 7510, USA
    Radiology 244:174-83. 2007
    ..To retrospectively determine the sensitivity and specificity of magnetic resonance (MR) imaging for differentiation between acute and chronic cholecystitis, with histopathologic analysis as the reference standard...
  18. ncbi Endoscopic naso-gallbladder drainage in the treatment of acute cholecystitis: alleviates inflammation and fixes operator's aim during early laparoscopic cholecystectomy
    Naoyuki Toyota
    Department of Surgery, Teikyo University School of Medicine, 2 11 1 Kaga cho, Itabashi ku, Tokyo 173 8605, Japan
    J Hepatobiliary Pancreat Surg 13:80-5. 2006
    ..Although surgery is often problematic in patients with acute cholecystitis because of inflammation, making Callot's triangle difficult to distinguish, the use of endoscopic naso-..
  19. ncbi Laparoscopic cholecystectomy for acute cholecystitis in the elderly: a retrospective study
    K E Coenye
    Brugmann University Hospital, Brussels, Belgium
    Hepatogastroenterology 52:17-21. 2005
    Laparoscopic cholecystectomy for acute cholecystitis in the elderly remains a subject almost unstudied. A first study performed at Brugmann hospital broached the subject, but was rather unsatisfying...
  20. ncbi Timing of laparoscopic cholecystectomy for acute cholecystitis: evidence to support a proposal for an early interval surgery
    Jee K Low
    Department of Surgery, Manchester Royal Infirmary, Manchester, United Kingdom
    Am Surg 73:1188-92. 2007
    ..to overcome the logistical difficulties in performing early urgent LC within 72 hours of admission with acute cholecystitis (AC), and to avoid earlier readmission with recurrent AC in patients awaiting delayed interval...
  21. doi Surgical outcomes of laparoscopic cholecystectomy for severe acute cholecystitis
    Ji Hun Kim
    Department of Surgery, School of Medicine, Ajou University, San 5, Wonchondong, Yeongtonggu, Suwon 442 749, South Korea
    J Gastrointest Surg 12:829-35. 2008
    ..the surgical outcomes of laparoscopic cholecystectomy (LC) in patients who were diagnosed with severe acute cholecystitis (SAC) and to clarify the useful treatment modalities of SAC...
  22. ncbi Conservative treatment versus endoscopic sphincterotomy in the initial management of acute cholecystitis in elderly patients at high surgical risk
    J Vracko
    Deparment of Gastroenterological Surgery, University Medical Center, Ljubljana, Slovenia
    Endoscopy 38:773-8. 2006
    Surgery in elderly patients with acute cholecystitis is quite a high-risk procedure...
  23. doi Meta-analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis
    K Gurusamy
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, London, UK
    Br J Surg 97:141-50. 2010
    In many countries laparoscopic cholecystectomy for acute cholecystitis is mainly performed after the acute episode has settled because of the anticipated increased risk of morbidity and higher conversion rate from laparoscopic to open ..
  24. doi Cost-utility and value-of-information analysis of early versus delayed laparoscopic cholecystectomy for acute cholecystitis
    E Wilson
    Health Economics Group, Faculty of Health, University of East Anglia, Norwich, UK
    Br J Surg 97:210-9. 2010
    ..cholecystectomy (ELC) to be safe and to shorten total hospital stay compared with delayed laparoscopic cholecystectomy (DLC) for acute cholecystitis. The cost-effectiveness of ELC versus DLC for acute cholecystitis is unknown.
  25. ncbi Evaluation of preoperative sonography in acute cholecystitis to predict technical difficulties during laparoscopic cholecystectomy
    Kyung Soo Cho
    Department of Radiology, College of Medicine, Ewha Womans University, Mokdong Hospital, 911 1, Mokdong, Yangcheon Ku, Seoul 158 710, South Korea
    J Clin Ultrasound 32:115-22. 2004
    The aim of this study was to evaluate the role of preoperative sonography in predicting technical difficulties during laparoscopic cholecystectomy in patients with acute cholecystitis.
  26. pmc First report of acute cholecystitis with sepsis caused by Cellulomonas denverensis
    Hirofumi Ohtaki
    Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
    J Clin Microbiol 47:3391-3. 2009
    ..Here we report a female case of acute cholecystitis and sepsis in which C. denverensis was determined to be causative.
  27. pmc Acute cholecystitis with massive upper gastrointestinal bleed: a case report and review of the literature
    Sundeep S Saluja
    Department of Gastrointestinal Surgery, AIIMS, Ansari Nagar, New Delhi, India
    BMC Gastroenterol 7:12. 2007
    ..Its presentation with upper gastrointestinal hemorrhage (UGIH) is even rarer. Thirteen patients with cystic artery pseudoaneurysm have been reported in the literature but only 2 of them presented with UGIH alone...
  28. ncbi Torsion of the gallbladder: a rare cause of acute cholecystitis
    David M Lemonick
    Department of Emergency Medicine, The Western Pennsylvania Hospital, 4800 Friendship Avenue, Pittsburgh, Pennsylvania, USA
    J Emerg Med 30:397-401. 2006
    ..Several clinical and imaging findings can be used to distinguish gallbladder torsion from typical acute cholecystitis. By recognizing and treating gallbladder torsion early in its course, a low surgical morbidity and ..
  29. ncbi Routine early laparoscopic cholecystectomy for acute cholecystitis after conclusion of a randomized controlled trial
    A Y B Teoh
    Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Br J Surg 94:1128-32. 2007
    The aim of this retrospective review was to assess the clinical outcomes of laparoscopic cholecystectomy for acute cholecystitis since the conclusion of a randomized controlled trial in 1997.
  30. doi A prospective evaluation of emergency department bedside ultrasonography for the detection of acute cholecystitis
    Shane M Summers
    Department of Emergency Medicine, University of California, Irvine, Orange, USA
    Ann Emerg Med 56:114-22. 2010
    ..We assess the diagnostic accuracy of emergency physician-performed bedside ultrasonography and radiology ultrasonography for the detection of cholecystitis, as determined by surgical pathology...
  31. doi Risk factors for acute cholecystitis and a complicated clinical course in patients with symptomatic cholelithiasis
    Jai Young Cho
    Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
    Arch Surg 145:329-33; discussion 333. 2010
    We prospectively evaluated the risk factors for acute cholecystitis (AC).
  32. doi Endosonography-guided gallbladder drainage for acute cholecystitis following covered metal stent deployment
    Osamu Takasawa
    Department of Gastroenterology, Sendai City Medical Center, Miyagino ku, Sendai, Japan
    Dig Endosc 21:43-7. 2009
    ..In order to relieve acute cholecystitis which developed in a patient with unresectable malignant biliary obstruction after deployment of a covered ..
  33. pmc Antimicrobial therapy for acute cholecystitis: Tokyo Guidelines
    Masahiro Yoshida
    Department of Surgery, Teikyo University School of Medicine, 2 11 1 Kaga, Itabashi ku, Tokyo, 173 8605, Japan
    J Hepatobiliary Pancreat Surg 14:83-90. 2007
    b>Acute cholecystitis consists of various morbid conditions, ranging from mild cases that are relieved by the oral administration of antimicrobial drugs or that resolve even without antimicrobials to severe cases complicated by biliary ..
  34. pmc Urgent cholecystectomy for acute cholecystitis in a district general hospital - is it feasible?
    M N Khan
    Department of General Surgery, Salisbury District Hospital, Salisbury, UK
    Ann R Coll Surg Engl 91:30-4. 2009
    ..However, its place remains controversial in the management of acute cholecystitis due to a high reported incidence of bile leaks and conversion rate...
  35. ncbi Laparoscopic cholecystectomy for severe acute cholecystitis. A meta-analysis of results
    Giuseppe Borzellino
    1st Department of General Surgery, OCM Borgo Trento Hospital, University of Verona, Verona, Italy
    Surg Endosc 22:8-15. 2008
    The aim of this review was to evaluate surgical outcomes of laparoscopic cholecystectomy for gangrenous and empyematous acute cholecystitis defined as severe acute cholecystitis.
  36. pmc Unusual cases of acute cholecystitis and cholangitis: Tokyo Guidelines
    Hideki Yasuda
    Department of Surgery, Teikyo University Chiba Medical Center, 3426 3 Anesaki, Ichihara, Chiba, 299 0111, Japan
    J Hepatobiliary Pancreat Surg 14:98-113. 2007
    Unusual cases of acute cholecystitis and cholangitis include (1) pediatric biliary tract infections, (2) geriatric biliary tract infections, (3) acalculous cholecystitis, (4) acute and intrahepatic cholangitis accompanying ..
  37. pmc Surgical treatment of patients with acute cholecystitis: Tokyo Guidelines
    Yuichi Yamashita
    Department of Surgery, Fukuoka University Hospital, Fukuoka University School of Medicine, 7 45 1 Nanakuma, Jonan ku, Fukuoka, 814 0180, Japan
    J Hepatobiliary Pancreat Surg 14:91-7. 2007
    Cholecystectomy has been widely performed in the treatment of acute cholecystitis, and laparoscopic cholecystectomy has been increasingly adopted as the method of surgery over the past 15 years...
  38. pmc Percutaneous gall bladder aspiration as an alternative to laparoscopic cholecystectomy in Child-Pugh C cirrhotic patients with acute cholecystitis
    G Curro
    Gut 55:898-9. 2006
  39. ncbi Acute cholecystitis at initial presentation of polyarteritis nodosa
    Sandra Regina Muchinechi Fernandes
    Disciplina de Reumatologia, Departamento de Clinica Medica, FCM UNICAMP, State University of Campinas, Sao Paulo, Brazil
    Clin Rheumatol 24:625-7. 2005
    ..We report a case of a 48-year-old man who was admitted due to acute cholecystitis. He had complained of myalgia, fever and weight loss for about one month prior to admission...
  40. doi Can acute cholecystitis with gallbladder perforation be detected preoperatively by computed tomography in ED? Correlation with clinical data and computed tomography features
    Ming Jen Tsai
    Department of Emergency Medicine, Buddhist Tzu Chi General Hospital, Hualien 970, Taiwan
    Am J Emerg Med 27:574-81. 2009
    The purpose of this study is to determine which computed tomography (CT) findings and clinical data can help to diagnose gallbladder perforation in acute cholecystitis.
  41. ncbi Percutaneous cholecystostomy in the management of acute cholecystitis
    William M K Teoh
    Upper G I Laparoscopic General Surgical Unit, Box Hill Hospital, Melbourne, Victoria, Australia
    ANZ J Surg 75:396-8. 2005
    Percutaneous cholecystostomy (PC) has been used in managing acute cholecystitis in the setting of a patient with severe comorbidities where emergency cholecystectomy would carry significant mortality...
  42. ncbi Bile duct injuries during laparoscopic cholecystectomy: primary and long-term results from a single institution
    Jukka Karvonen
    Department of Surgery, University of Turku, Turku, Finland
    Surg Endosc 21:1069-73. 2007
    ..After the introduction of laparoscopic cholecystectomy the incidence of these injuries has at least doubled, and even after the learning curve, the incidence has plateaued at the level of 0.5%...
  43. ncbi Early versus delayed cholecystectomy for acute cholecystitis: a meta-analysis of randomized controlled trials
    Satoru Shikata
    Department of Surgery, Division of Digestive Surgery, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
    Surg Today 35:553-60. 2005
    We performed a meta-analysis of randomized controlled trials to determine the optimal timing of laparoscopic cholecystectomy and open cholecystectomy for acute cholecystitis.
  44. ncbi Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: a meta-analysis of randomized clinical trials
    Tamim Siddiqui
    Department of Surgery, Southern General Hospital, Glasgow, Scotland
    Am J Surg 195:40-7. 2008
    The appropriate timing for laparoscopic cholecystectomy in the treatment of acute cholecystitis remains controversial...
  45. ncbi Endoscopic gallbladder drainage of patients with acute cholecystitis
    D W Kjaer
    Surgical Gastroenterological Department L, Aarhus University Hospital, Aarhus, Denmark
    Endoscopy 39:304-8. 2007
    The standard treatment for acute cholecystitis is early laparoscopic cholecystectomy...
  46. ncbi Early versus delayed-interval laparoscopic cholecystectomy for acute cholecystitis: a metaanalysis
    H Lau
    Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong SAR, People s Republic of China
    Surg Endosc 20:82-7. 2006
    Early laparoscopic cholecystectomy has been advocated for the management of acute cholecystitis, but little evidence exists to support the superiority of this approach over delayed-interval operation...
  47. ncbi Gallstone disease: Surgical aspects of symptomatic cholecystolithiasis and acute cholecystitis
    F Keus
    Diakonessenhuis, Bosboomstraat 1, 3582 KE Utrecht, The Netherlands
    Best Pract Res Clin Gastroenterol 20:1031-51. 2006
    ..b>Acute cholecystitis is a complication of gallstones...
  48. ncbi Timing of laparoscopic cholecystectomy for acute cholecystitis: a prospective non randomized study
    George Tzovaras
    Department of Surgery, University of Thessaly School of Medicine, University Hospital of Larissa, 19 Agorogianni A Street, Larissa 41335, Greece
    World J Gastroenterol 12:5528-31. 2006
    To study the timing of laparoscopic cholecystectomy for patients with acute cholecystitis.
  49. ncbi A prospective study of bile leaks after laparoscopic cholecystectomy for acute cholecystitis
    Edward P Dominguez
    Riverside Methodist Hospital, Department of Surgery, Columbus, Ohio, USA
    Am Surg 72:265-8. 2006
    Surgeons are increasingly performing laparoscopic cholecystectomy in the setting of acute cholecystitis. The acutely inflamed gallbladder poses a more technically demanding dissection with potential for an increase in bile leak rates...
  50. ncbi Role of fundus-first laparoscopic cholecystectomy in the management of acute cholecystitis in elderly patients
    Yu Chun Wang
    Trauma and Emergency Center, China Medical University Hospital, Taichung, Taiwan
    J Laparoendosc Adv Surg Tech A 16:124-7. 2006
    ..The conversion from laparoscopic to open cholecystectomy is more frequent among patients with acute cholecystitis and in elderly patients...
  51. ncbi Is there an optimal time for laparoscopic cholecystectomy in acute cholecystitis?
    D Soffer
    Division of Trauma, University of Miami Miller School of Medicine, P O Box 016960 D 40, Miami, Florida 33101, USA
    Surg Endosc 21:805-9. 2007
    Laparoscopic cholecystectomy (LC) is safe in acute cholecystitis, but the exact timing remains ill-defined. This study evaluated the effect of timing of LC in patients with acute cholecystitis.
  52. ncbi Immediate laparoscopic cholecystectomy for acute cholecystitis: no need to wait
    Kent A Stevens
    University of Arizona Health Sciences Center, Trauma Critical Care, Rm 5411, 1501 N Campbell Avenue, Tucson, AZ 85724 5063, USA
    Am J Surg 192:756-61. 2006
    ..Early, within 72 hours, laparoscopic cholecystectomy (LC) for acute chlolecystitis (AC) is the standard of care. We reviewed our experience with immediate (within 24 hours) LC for AC to determine whether this also was safe...
  53. ncbi The safety of a laparoscopic cholecystectomy in acute cholecystitis in high-risk patients older than sixty with stratification based on ASA score
    Nam Joon Yi
    Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
    Minim Invasive Ther Allied Technol 15:159-64. 2006
    The purpose of this study was to evaluate the safety of a laparoscopic cholecystectomy (LC) for acute cholecystitis (AC) in patients older than sixty years of age, with stratification based on the ASA (American Society of ..
  54. ncbi Urgent laparoscopic cholecystectomy in the management of acute cholecystitis: timing does not influence conversion rate
    Y C Wang
    Department of Surgery, China Medical University Hospital, No 2, Yuh Der Road, Taichung, 404, Taiwan
    Surg Endosc 20:806-8. 2006
    The optimal treatment of acute cholecystitis is urgent laparoscopic cholecystectomy. Most reports suggest that a delay of 72 or 96 h from onset of symptoms leads to a higher conversion rate...
  55. ncbi Contemporary minimally invasive approaches to the management of acute cholecystitis: a review and appraisal
    Debashish Bhattacharya
    Manchester Royal Infirmary, Manchester M13 9WL, UK
    Surg Laparosc Endosc Percutan Tech 15:1-8. 2005
    b>Acute cholecystitis is one of the most common emergency admissions in surgical practice...
  56. ncbi Sex-based analysis of the outcome of laparoscopic cholecystectomy for acute cholecystitis
    H K Lee
    Department of Surgery and Medical Research Centre, Ewha Women s University College of Medicine, Seoul, Korea
    Br J Surg 92:463-6. 2005
    Complicated acute cholecystitis, for example when empyema or gangrene is present, is associated with increased postoperative morbidity and mortality rates...
  57. doi Laparoscopic cholecystectomy for acute cholecystitis
    Angel Iliev Popkharitov
    Department of Surgery, Neurosurgery and Urology, Medical Faculty, Thracian University, Stara Zagora, Bulgaria
    Langenbecks Arch Surg 393:935-41. 2008
    ..aim of this study is to present our experience and results with performing laparoscopic cholecystectomy for acute cholecystitis evaluating the effect of timing of surgery and the influence of the various types of gallbladder ..
  58. doi Percutaneous cholecystostomy: a bridge to surgery or definite management of acute cholecystitis in high-risk patients?
    Per Leveau
    Department of Surgery, Lund University Hospital, Lund, Sweden
    Scand J Gastroenterol 43:593-6. 2008
    Cholecystectomy is the standard treatment for acute cholecystitis, but in high-risk patients with serious comorbidity and in patients of advanced age there is substantial morbidity and mortality associated with the intervention...
  59. pmc Metastatic melanoma of the gallbladder: an unusual clinical presentation of acute cholecystitis
    Spiridon Vernadakis
    4th Department of Surgery, Athens University School of Medicine, Attikon General Hospital, Rimini 1, 12462 Chaidari, Athens, Greece
    World J Gastroenterol 15:3434-6. 2009
    ..man who arrived at our clinic with acute abdominal pain, which, after investigation, was diagnosed as acute cholecystitis. The patient underwent laparotomy and cholecystectomy...
  60. ncbi Early or delayed laparoscopic cholecystectomy in acute cholecystitis? Conclusions of a controlled trial
    Francisco J Gonzalez-Rodriguez
    Department of Surgery, Hospital Clinico Universitario, Medical School, Santiago de Compostela, Spain
    Hepatogastroenterology 56:11-6. 2009
    Laparoscopic cholecystectomy is now accepted as being safe for acute cholecystitis. However, it has not become routine, because the exact timing and approach to the surgical management remains ill defined...
  61. pmc Is complicated gallstone disease preceded by biliary colic?
    Marc G Besselink
    Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    J Gastrointest Surg 13:312-7. 2009
    ....
  62. pmc Timing of early laparoscopic cholecystectomy for acute cholecystitis
    Abdulmohsen A Al-Mulhim
    Department of Surgery, King Fahd Hospital of the University, Al Khobar, Saudi Arabia
    JSLS 12:282-7. 2008
    Although many surgeons advocate early laparoscopic cholecystectomy (LC) in acute cholecystitis, debate still exists regarding its optimal timing...
  63. ncbi Acute cholecystitis: when is the best time for laparoscopic cholecystectomy?
    Nicolas Condilis
    Surgical Dept General Hospital of Nikaia Saint Panteleimon, Piraeus, Greece
    Ann Ital Chir 79:23-7. 2008
    ..The question is when to perform laparoscopic cholecystectomy in the face of acute cholecystitis. The last decade (1995-2004) 297 patients had a laparoscopic cholecystectomy for acute cholecystitis...
  64. pmc Predicting the success of endoscopic transpapillary gallbladder drainage for patients with acute cholecystitis during pretreatment evaluation
    Osamu Ogawa
    Showa University Fujigaoka Hospital, Aoba ku, Yokohama, Japan
    Can J Gastroenterol 22:681-5. 2008
    ..endoscopic transpapillary gallbladder drainage (ETGBD) has been reported to be an effective treatment for acute cholecystitis, technical difficulties have precluded more widespread use of this technique...
  65. doi Early laparoscopic cholecystectomy is the preferred management of acute cholecystitis
    Robert A Casillas
    Kaiser Permanente Los Angeles Medical Center, 4760 Sunset Blvd, Third Floor, Los Angeles, CA 90027, USA
    Arch Surg 143:533-7. 2008
    ..rates when compared with antibiotic therapy plus interval LC or percutaneous cholecystostomy in patients admitted to a surgical service because of acute cholecystitis. However, actual practice does not conform to current evidence.
  66. ncbi Gallbladder perforation: a rare complication of acute cholecystitis
    Saad Akhtar Khan
    Department of Surgery, Ziauddin University Hospital, Karachi
    J Pak Med Assoc 60:228-9. 2010
    ..It is usually a complication of acute cholecystitis with or without gallstones. We present a case of 70-year-old female with abdominal pain and fever...
  67. doi Trends in surgical management for acute cholecystitis
    Nicholas G Csikesz
    Surgical Outcomes Analysis and Research, Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Surgery 144:283-9. 2008
    ..be performed with either a laparoscopic (LC) or open (OC) approach, remains the definitive treatment for acute cholecystitis (AC) in the United States. There has not been an overall evaluation of the safety and efficacy of LC vs...
  68. ncbi Randomized clinical trial of open versus laparoscopic cholecystectomy in the treatment of acute cholecystitis
    M Johansson
    Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
    Br J Surg 92:44-9. 2005
    The aim of this prospective trial was to determine whether surgical approach (open versus laparoscopic) had an impact on morbidity and postoperative recovery after cholecystectomy for acute cholecystitis.
  69. ncbi Percutaneous cholecystostomy for the treatment of acute cholecystitis in the critically ill and elderly
    J C M Li
    Department of Surgery, North District Hospital, New Territories East Cluster, 9 Po Kin Road, Sheung Shui, Hong Kong
    Hong Kong Med J 10:389-93. 2004
    To evaluate the clinical efficacy and outcomes of percutaneous cholecystostomy as an alternative treatment option for elderly and critically ill patients who have acute cholecystitis.
  70. ncbi Epiploic appendagitis mimicking acute cholecystitis
    Wan Ching Lien
    Am J Emerg Med 22:507-8. 2004
  71. ncbi Acute cholecystitis with a hemocholecyst as an unusual presentation of gallbladder cancer: report of a case
    Joseph Ku
    Division of Trauma, Department of Surgery, University of California San Diego, School of Medicine, 200 West Arbor Drive, San Diego, CA 92103 8896, USA
    Surg Today 34:973-6. 2004
    ..We report a case of carcinoma of the gallbladder disclosed by an emergency cholecystectomy, performed for acute cholecystitis caused by a hemocholecyst...
  72. ncbi Fitz-Hugh-Curtis-syndrome mimicking acute cholecystitis: value of new ultrasound findings in the differential diagnosis
    F Piscaglia
    Div Internal Medicine, Dept of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Ultraschall Med 26:227-30. 2005
    ..This prompted laparoscopic exploration of the subdiaphragmatic space, and the final diagnosis of Fitz-Hugh-Curtis-syndrome was made. Such ultrasound finding appears to be a new diagnostic feature of this syndrome...
  73. doi Laparoscopic cholecystectomy for acute cholecystitis in the elderly: is it safe?
    Boris Kirshtein
    Department of Surgery A Soroka Medical Center, Department of Epidemiology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Surg Laparosc Endosc Percutan Tech 18:334-9. 2008
    The purpose of this study was to evaluate the outcome of laparoscopic cholecystectomy (LC) in patients with acute cholecystitis aged 75 years and older.
  74. ncbi Variation in the use of laparoscopic cholecystectomy for acute cholecystitis: a population-based study
    Chi Ming Lam
    Central Surgical Audit Unit, Hospital Authority, Hong Kong, China
    Arch Surg 140:1084-8. 2005
    There is wide variation in the use of laparoscopic cholecystectomy (LC) for acute cholecystitis among all public hospitals in Hong Kong...
  75. pmc Etiological misidentification by routine biochemical tests of bacteremia caused by Gordonia terrae infection in the course of an episode of acute cholecystitis
    E Gil-Sande
    Microbiology Department, Hospital San Rafael, Coruña Spain
    J Clin Microbiol 44:2645-7. 2006
    ..We report the first case of bacteremia associated with acute cholecystitis. Commercial biochemical testing was not able to identify the strain at the genus level, classifying it ..
  76. ncbi Acute cholecystitis, biliary obstruction, and biliary leakage
    Harvey A Ziessman
    Division of Nuclear Medicine, Georgetown University Hospital, Washington, DC, USA
    Semin Nucl Med 33:279-96. 2003
    The use of cholescintigraphy to diagnose acute cholecystitis, biliary obstruction, and biliary leakage dates back to the late 1970s...
  77. ncbi Laparoscopic cholecystectomy in acute cholecystitis: indication, technique, risk and outcome
    U Giger
    Department of Surgery, Hopital Cantonal Fribourg, 1700, Fribourg, Switzerland
    Langenbecks Arch Surg 390:373-80. 2005
    ..However, the laparoscopic approach has remained controversial for patients with acute cholecystitis (AC) because of technical difficulties that, compared with open cholecystectomy (OC), might lead to higher ..
  78. ncbi Bile duct injuries at laparoscopic cholecystectomy: a single-institution prospective study. Acute cholecystitis indicates an increased risk
    Claes Soderlund
    Upper GI Surgery Section, Department of Surgery, Stockholm South Hospital, SE 118 83 Stockholm, Sweden
    World J Surg 29:987-93. 2005
    ..Major BDs were transected in five patients (0.3%), three of whom had acute cholecystitis. In the two patients operated on electively, the BD injuries were detected postoperatively, while they were ..
  79. ncbi Risk factors for conversion to open surgery in patients with acute cholecystitis undergoing interval laparoscopic cholecystectomy
    Kok Ren Lim
    Department of General Surgery, Changi General Hospital, Singapore
    Ann Acad Med Singapore 36:631-5. 2007
    Laparoscopic cholecystectomy for acute cholecystitis is associated with higher rate of conversion to laparotomy. The value of several factors that might influence the rate of conversion is analysed.
  80. pmc Laparoscopic cholecystectomy for acute cholecystitis in elderly patients
    Paulo Cezar Galvão do Amaral
    General Surgery Division, São Rafael Hospital, Department of Surgery, Escola Bahiana de Medicina e Saude Publica, Salvador, Bahia, Brazil
    JSLS 10:479-83. 2006
    b>Acute cholecystitis is the major complication of biliary lithiasis, for which laparoscopic treatment has been established as the standard therapy...
  81. ncbi Ultrasound guided percutaneous cholecystostomy in high-risk patients for surgical intervention
    Huseyin Bakkaloglu
    Trauma and Emergency Surgery Service, Istanbul University, Istanbul Faculty of Medicine, Capa Istanbul 34390, Turkey
    World J Gastroenterol 12:7179-82. 2006
    To assess the efficacy and safety of ultrasound guided percutaneous cholecystostomy (PC) in the treatment of acute cholecystitis in a well-defined high risk patients under general anesthesia.
  82. pmc Laparoscopic cholecystectomy: a safe approach for management of acute cholecystitis
    Stavros Gourgiotis
    Department of Hepatobiliary and Pancreatic Surgery, Royal London Hospital, UK
    JSLS 11:219-24. 2007
    Laparoscopic cholecystectomy (LC) is increasingly being used as an appropriate early treatment in patients with cholecystitis. This study evaluated the safety, effectiveness, and complications of LC in all cases of acute cholecystitis.
  83. ncbi Laparoscopic cholecystectomy as solo surgery with the aid of a robotic camera holder: a case-control study
    Manfred Kalteis
    Surgical Department of St Franziskus Hospital, Grieskirchen, Austria
    Surg Laparosc Endosc Percutan Tech 17:277-82. 2007
    ..By using robotic camera holders, a laparoscopic cholecystectomy (LC) is possible as a solo-surgeon operation. The purpose of this paper is to examine the safeness and efficiency of solo-surgeon LCs...
  84. ncbi [Laparoscopic surgery for acute cholecystitis in the elderly. Our experience]
    Olimpio Guerriero
    UOC di Chirurgia Generale e d Urgenza, Ospedale AGP di Piedimonte Matese Caserta, Azienda Sanitaria Locale Caserta 1
    Chir Ital 60:189-97. 2008
    b>Acute cholecystitis in the elderly is a severe illness with high operative risks and mortality, which, even if less than in the past, is still too high...
  85. ncbi [Simultaneous laparoscopic treatment for common bile duct stones associated with acute cholecystitis. Results of a prospective study]
    Massimo Chiarugi
    UO Univ Chirurgia Generale e Urgenza, Dipartimento di Chirurgia, Universita degli Studi di Pisa, Via Roma, 67 56100 Pisa
    Chir Ital 58:709-16. 2006
    Laparoscopy for the management of acute cholecystitis has gained wide acceptance...
  86. ncbi Cholecystectomy following acute presentation to a major New Zealand metropolitan hospital: change to the timing of surgery is needed
    Anthony Lin
    Christchurch School of Medicine and Health Sciences, University of Otago
    N Z Med J 119:U2104. 2006
    ..To review the management and outcome of patients presenting with acute biliary pain/cholecystitis, mild acute pancreatitis, or cholangitis to a major New Zealand (NZ) metropolitan hospital...
  87. ncbi Systemic immune response after open versus laparoscopic cholecystectomy in acute cholecystitis: a prospective randomized study
    Y J Boo
    Department of Surgery, Korea University College of Medicine, Seoul, Korea
    Scand J Clin Lab Invest 67:207-14. 2007
    ..The aim of this study is to evaluate the influence of surgical trauma on systemic inflammation and the immune response in acute cholecystitis.
  88. ncbi Surgery for acute cholecystitis in Denmark
    Alan P Ainsworth
    Department of Surgery, Odense University Hospital, Denmark
    Scand J Gastroenterol 42:648-51. 2007
    Despite laparoscopic cholecystectomy being the preferred treatment for elective cholecystectomy, surgery for acute cholecystitis is often performed using the open method...
  89. ncbi Early laparoscopic cholecystectomy for acute gangrenous cholecystitis
    Takaaki Tsushimi
    Department of Surgery, Shutoh General Hospital, 1000 1 Kogaisaku, Yanai, Yamaguchi 742 0032, Japan
    Surg Laparosc Endosc Percutan Tech 17:14-8. 2007
    Treatment of severe acute cholecystitis by laparoscopic cholecystectomy remains controversial because of technical difficulties and high rates of complications and conversion to open cholecystectomy...
  90. ncbi Partial cholecystectomy as a safe and viable option in the emergency treatment of complex acute cholecystitis: a case series and review of the literature
    Mehrdad Soleimani
    Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran
    Am Surg 73:498-507. 2007
    ..Fifty-four patients with complex acute cholecystitis underwent PC, including conventional partial cholecystectomy (CPC; n = 48) and laparoscopic partial ..
  91. ncbi Somatosensory changes in the referred pain area in patients with acute cholecystitis before and after treatment with laparoscopic or open cholecystectomy
    M Stawowy
    Department of Surgical Gastroenterology L, Aarhus University Hospital, Denmark
    Scand J Gastroenterol 39:988-93. 2004
    ..pain can be offered in up to 30%, it could be hypothesized that altered sensory characteristics induced by acute cholecystitis could persist in some patients and thus be responsible for postcholecystectomy pain...
  92. pmc Three-port versus four-port laparoscopic cholecystectomy in acute and chronic cholecystitis
    Dhafir Al-azawi
    Department of Surgery, Royal College of Surgeons in Ireland, Dublin Ireland
    BMC Surg 7:8. 2007
    ..The three-port technique has been practiced on a limited scale. Our aim was to compare the three-port and four-port LC in acute (AC) and chronic cholecystitis (CC)...
  93. ncbi A 14-year analysis of laparoscopic cholecystectomy: conversion--when and why?
    Andreas Shamiyeh
    Ludwig Boltzmann Institute for Operative Laparoscopy, II Surgical Department, AKH Linz, Linz, Austria
    Surg Laparosc Endosc Percutan Tech 17:271-6. 2007
    ..diminished over the last decade but still conversion is about 5% to 6% in elective cases and higher in acute cholecystitis. The aim of this study was to analyze the reason for conversion in all patients operated on in our ..
  94. ncbi The contribution of acute cholecystitis, obesity, and previous abdominal surgery on the outcome of laparoscopic cholecystectomy
    Constantinos Simopoulos
    Second Department of Surgery, Democritus University of Thrace, Alexandroupolis, Greece
    Am Surg 73:371-6. 2007
    The aim of this study was to evaluate the impact of acute cholecystitis (AC), obesity, and previous abdominal surgery on laparoscopic cholecystectomy (LC) outcomes...
  95. ncbi Hepatic vein injury during laparoscopic cholecystectomy: the unappreciated proximity of the middle hepatic vein to the gallbladder bed
    Chad G Ball
    Department of Surgery, Foothills Medical Centre, Calgary, Alberta, Canada
    J Gastrointest Surg 10:1151-5. 2006
    ..These patients are at increased risk for intraoperative bleeding. Furthermore, contracted gallbladders with evidence of chronic disease may be at increased risk for significant hemorrhage...
  96. pmc Removing symptomatic gallstones at their first emergency presentation
    Hanny A Anwar
    Department of General and Laparoscopic Surgery, Princess Alexandra Hospital, Harlow, UK
    Ann R Coll Surg Engl 90:394-7. 2008
    ..This study was performed to clarify how frequently early operations were being performed and what benefits resulted...
  97. pmc Percutaneous transhepatic gall bladder drainage: a better initial therapeutic choice for patients with gall bladder perforation in the emergency department
    C C Huang
    Department of Emergency Medicine, Cathay General Hospital, Taipei, Taiwan
    Emerg Med J 24:836-40. 2007
    To investigate clinical features and outcomes in patients with acute cholecystitis with gall bladder perforation receiving open cholecystectomy or percutaneous transhepatic gall bladder drainage in the emergency department.
  98. ncbi Acute gallstone cholecystitis in the elderly: treatment with emergency ultrasonographic percutaneous cholecystostomy and interval laparoscopic cholecystectomy
    A Macri
    Emergency Surgery Unit, University of Messina, Messina 98125, Italy
    Surg Endosc 20:88-91. 2006
    The treatment of acute cholecystitis in the elderly is still a subject of debate, particularly with reference to the timing of surgery and the role of laparoscopy.
  99. doi Does gender affect laparoscopic cholecystectomy?
    Sotirios Botaitis
    Second Department of Surgery, Democritus University of Thrace, Alexandroupolis, Greece
    Surg Laparosc Endosc Percutan Tech 18:157-61. 2008
    ..to have coexisting cardiovascular disease, previous upper abdominal surgery, previous hospitalization for acute cholecystitis and pancreatitis, acute cholecystitis, and suppurative cholecystitis (such as empyema), conversions, and ..
  100. ncbi [Laparoscopic cholecystectomy for acute cholecystitis]
    Marcin Kondras
    Uniwersytet Medyczny w Łodzi, Klinika Chirurgii Gastroenterologicznej, Onkologicznej i Ogóllnej
    Pol Merkur Lekarski 23:92-4. 2007
    ..Currently this method is used in 88% of cholecystectomy according to world database. There are evidences that laparoscopic cholecystectomy for acute cholecystitis is a quite safe method which is not connected with many complications.
  101. ncbi Hemobilia in a patient with protein S deficiency after laparoscopic cholecystectomy that caused acute pancreatitis: successful endoscopic management
    David S Wolf
    Department of Internal Medicine, The University of Texas Houston Health Science Center, Texas 77030, USA
    Gastrointest Endosc 62:163-6. 2005

Research Grants25

  1. MYOGENIC DISORDERS OF THE GALLBLADDER
    Jose Behar; Fiscal Year: 2004
    b>Acute cholecystitis (AC) affects 88% of patients with symptomatic gallbladder (GB) stones over a 18 year period and has a significant morbidity and mortality in elderly patients...
  2. GALLBLADDER MUSCARINIC RECEPTORS IN ACUTE CHOLECYSTITIS
    Stuart Myers; Fiscal Year: 2001
    ..This proposal will provide insight into both the pathophysiology of acute cholecystitis and the general mechanisms involved in decreasing gallbladder contractility during initiation of acute ..
  3. INJURY TO LIVER SINUSOIDAL ENDOTHELIAL CELLS
    Steven Strasberg; Fiscal Year: 2003
    ..A potentially beneficial improvements in preservation solutions are identified they will be tested in whole isolated livers and by transplantation in the rat. ..