vascular neoplasms

Summary

Summary: Neoplasms located in vascular tissue or specific veins. They are differentiated from NEOPLASMS, VASCULAR TISSUE which are neoplasms composed of vascular tissue, such as ANGIOFIBROMA or HEMANGIOMA.

Top Publications

  1. ncbi Leiomyosarcoma of the inferior vena cava
    Suhaila Ameeri
    Department of Pathology, Toronto Medical Laboratories, Toronto General Hospital University Health Network, Toronto, Ontario, Canada
    Cardiovasc Pathol 15:171-3. 2006
  2. doi Chronic DLL4 blockade induces vascular neoplasms
    Minhong Yan
    Department of Tumor Biology and Angiogenesis, Genentech Inc, 1 DNA Way, South San Francisco, California 94080, USA
    Nature 463:E6-7. 2010
  3. ncbi Expression of apoptosis-related proteins, p53, and DNA fragmentation in sarcomas of the pulmonary artery
    A Gaumann
    Institute of Pathology, University of Mainz, Mainz, Germany
    Cancer 92:1237-44. 2001
  4. doi Inferior vena cava leiomyosarcoma: is reconstruction necessary after resection?
    Rouzbeh Daylami
    Department of Surgery, University of California Davis Medical Center, Sacramento, CA
    J Am Coll Surg 210:185-90. 2010
  5. ncbi Intimal angiosarcoma of the aorta with tumour embolisation causing mesenteric ischaemia. Report of a case diagnosed using CD31 immunohistochemistry in an intestinal resection specimen
    C Santonja
    Department of Pathology, Hospital Universitario de Getafe, Carretera de Toledo, km 12 5 Getafe E 28905, Madrid, Spain
    Virchows Arch 438:404-7. 2001
  6. ncbi Surgical treatment of pulmonary artery sarcoma
    E Mayer
    Department for Cardiothoracic and Vascular Surgery, Pathology, and Radiology, Johannes Gutenberg University, Mainz, Germany
    J Thorac Cardiovasc Surg 121:77-82. 2001
  7. ncbi PET-positive fibrous dysplasia--a potentially misleading incidental finding in a patient with intimal sarcoma of the pulmonary artery
    Klaus Strobel
    Division of Nuclear Medicine, Department of Medical Radiology, University Hospital, Zurich, Switzerland
    Skeletal Radiol 36:S24-8. 2007
  8. ncbi Osteopontin expression in primary sarcomas of the pulmonary artery
    A Gaumann
    MPI für Physiologische und Klinische Forschung, W G Kerckhoff Institut, Abt für Molekulare Zellbiologie, Bad Nauheim, Germany
    Virchows Arch 439:668-74. 2001
  9. ncbi Gains of 12q13-14 and overexpression of mdm2 are frequent findings in intimal sarcomas of the pulmonary artery
    B Bode-Lesniewska
    Department of Pathology, University Hospital, Zurich, Switzerland
    Virchows Arch 438:57-65. 2001
  10. doi Surgical management of leiomyosarcoma of the inferior vena cava
    S W Cho
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    J Gastrointest Surg 12:2141-8. 2008

Detail Information

Publications230 found, 100 shown here

  1. ncbi Leiomyosarcoma of the inferior vena cava
    Suhaila Ameeri
    Department of Pathology, Toronto Medical Laboratories, Toronto General Hospital University Health Network, Toronto, Ontario, Canada
    Cardiovasc Pathol 15:171-3. 2006
    ..They are generally recognized to be of smooth muscle cell origin. Surgical resection is the treatment of choice. The role of adjuvant therapy for leiomyosarcoma is not established...
  2. doi Chronic DLL4 blockade induces vascular neoplasms
    Minhong Yan
    Department of Tumor Biology and Angiogenesis, Genentech Inc, 1 DNA Way, South San Francisco, California 94080, USA
    Nature 463:E6-7. 2010
    ..Here we show that chronic DLL4 blockade causes pathological activation of endothelial cells, disrupts normal organ homeostasis and induces vascular tumours, raising important safety concerns...
  3. ncbi Expression of apoptosis-related proteins, p53, and DNA fragmentation in sarcomas of the pulmonary artery
    A Gaumann
    Institute of Pathology, University of Mainz, Mainz, Germany
    Cancer 92:1237-44. 2001
    ..In particular, members of the Bcl-2 family as well as the Fas system are known to be involved in the regulation of apoptosis in different tumor entities...
  4. doi Inferior vena cava leiomyosarcoma: is reconstruction necessary after resection?
    Rouzbeh Daylami
    Department of Surgery, University of California Davis Medical Center, Sacramento, CA
    J Am Coll Surg 210:185-90. 2010
    ..Leiomyosarcomas of the inferior vena cava represent a rare form of soft-tissue sarcomas. Management strategies necessarily vary because of limited experience. Questions about necessity of multimodality therapy and IVC reconstruction remain...
  5. ncbi Intimal angiosarcoma of the aorta with tumour embolisation causing mesenteric ischaemia. Report of a case diagnosed using CD31 immunohistochemistry in an intestinal resection specimen
    C Santonja
    Department of Pathology, Hospital Universitario de Getafe, Carretera de Toledo, km 12 5 Getafe E 28905, Madrid, Spain
    Virchows Arch 438:404-7. 2001
    ..This case emphasises the need for a wide panel of immunohistochemical antibodies when tumour emboli of unknown origin are under study...
  6. ncbi Surgical treatment of pulmonary artery sarcoma
    E Mayer
    Department for Cardiothoracic and Vascular Surgery, Pathology, and Radiology, Johannes Gutenberg University, Mainz, Germany
    J Thorac Cardiovasc Surg 121:77-82. 2001
    ..Surgical resection improves clinical symptoms and offers the only chance of cure. We report the case histories of 7 patients with primary pulmonary artery sarcomas treated by surgical resection with or without adjuvant therapy...
  7. ncbi PET-positive fibrous dysplasia--a potentially misleading incidental finding in a patient with intimal sarcoma of the pulmonary artery
    Klaus Strobel
    Division of Nuclear Medicine, Department of Medical Radiology, University Hospital, Zurich, Switzerland
    Skeletal Radiol 36:S24-8. 2007
    ..In the presented case, an incidentally detected PET-positive asymptomatic fibrous dysplasia was initially misinterpreted as a metastasis in a patient with intimal sarcoma of the pulmonary artery...
  8. ncbi Osteopontin expression in primary sarcomas of the pulmonary artery
    A Gaumann
    MPI für Physiologische und Klinische Forschung, W G Kerckhoff Institut, Abt für Molekulare Zellbiologie, Bad Nauheim, Germany
    Virchows Arch 439:668-74. 2001
    ....
  9. ncbi Gains of 12q13-14 and overexpression of mdm2 are frequent findings in intimal sarcomas of the pulmonary artery
    B Bode-Lesniewska
    Department of Pathology, University Hospital, Zurich, Switzerland
    Virchows Arch 438:57-65. 2001
    ..A majority of tumors show a consistent genetic alteration (gains and amplifications in the 12q13-14 region) and overexpression of mdm2, implicating the mdm2/p53 pathway as a possible mechanism in the tumor pathogenesis...
  10. doi Surgical management of leiomyosarcoma of the inferior vena cava
    S W Cho
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    J Gastrointest Surg 12:2141-8. 2008
    ..Due to its rarity, however, optimal strategies for the management of the primary tumor and subsequent recurrences are not well defined...
  11. doi Primary intimal pulmonary artery sarcoma: a diagnostic challenge
    Hans Scheffel
    Institute of Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland
    J Thorac Cardiovasc Surg 135:949-50. 2008
  12. pmc Intimal sarcoma of the pulmonary artery with retrograde extension into the pulmonic valve and right ventricle
    Cengiz Ozbek
    Department of Cardiovascular Surgery, Izmir Ataturk Training and Research Hospital, 35820 Izmir, Turkey
    Tex Heart Inst J 34:119-21. 2007
    ..He underwent surgery for obstruction of the right ventricular outflow tract. This is a very rare case of an intimal sarcoma of the pulmonary artery, which we confirmed by pathologic studies...
  13. ncbi Vascular smooth muscle tumors: review of the literature
    Ilias Dalainas
    492 General Military Hospital, Alexandroupolis, Greece
    Int J Surg 6:157-63. 2008
    ..This study reviews literature for epidemiology, clinical presentation, diagnosis and management of patients with vascular smooth muscle tumors...
  14. ncbi Tumors of the pulmonary vasculature
    Eunhee S Yi
    Department of Clinical Pathology, University of California, San Diego School of Medicine, 200 West Arbor Drive, San Diego, CA 92103 8720, USA
    Cardiol Clin 22:431-40, vi-vii. 2004
    ..Secondary involvement of pulmonary vasculature by malignant tumors may rarely mimic a primary vascular tumor or clinically present as unexplained pulmonary hypertension associated with thrombotic microangiopathy...
  15. doi Neoadjuvant radiotherapy and reconstruction using autologous vein graft for the treatment of inferior vena cava leiomyosarcoma
    Gitonga Munene
    Department of Surgery, Divisions of Surgical Oncology and General Surgery, University of Calgary and the Tom Baker Cancer Centre, Calgary, Alberta, Canada
    J Surg Oncol 103:175-8. 2011
    ..This study was undertaken to analyze the outcomes associated with the use of neoadjuvant radiotherapy and IVC reconstruction in the treatment of IVC leiomyosarcoma...
  16. doi Pulmonary artery intimal sarcoma: the role of ¹⁸F-fluorodeoxyglucose positron emission tomography in monitoring response to treatment
    Enrique Leonardo P Ote
    Department of Nuclear Medicine, St Luke s Medical Center, Manila, Philippines
    Jpn J Radiol 29:279-82. 2011
    ..Fine-needle biopsy revealed a pathological diagnosis of pulmonary artery intimal sarcoma. The patient was successfully treated with radiotherapy and adjuvant chemotherapy. FDG-PET was used for monitoring the response to therapy...
  17. doi Leiomyosarcoma of the infra-renal inferior vena cava
    Osama H Al-Saif
    Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia
    Am J Surg 201:e18-20. 2011
    ..Complete surgical resection offers the only potential of long-term survival, but survival of unresected patients is generally measured in months. Palliative resections may temporarily improve symptoms but do not offer long-term survival...
  18. doi Leiomyosarcoma of the inferior vena cava: resection and vascular reconstruction using a dacron graft and an Adam DeWeese clip-three-year follow-up
    Domenico Angiletta
    Vascular Surgery Unit Policlinico Universitario Bari, Bari, Italy
    Ann Vasc Surg 25:557.e5-9. 2011
    ..The latter procedure has never been reported before in association with a graft applied for this disease. Technical and clinical details are described...
  19. ncbi Intimal-type primary sarcoma of the aorta. Report of a case with evidence of rhabdomyosarcomatous differentiation
    C Miracco
    Institute of Pathological Anatomy and Histology, University of Siena, Italy
    Virchows Arch 435:62-6. 1999
    ..Electron microscopy and the use of a more comprehensive panel of immunohistochemical markers should be applied in the histological classification of"intimal" sarcoma...
  20. doi High frequency of neurolymphomatosis as a relapse disease of intravascular large B-cell lymphoma
    Kosei Matsue
    Division of Hematology Oncology, Department of Medicine, Kameda Medical Center, Kamogawa shi, Chiba, Japan
    Cancer 117:4512-21. 2011
    ..A high incidence of neurologic symptoms associated with the central nervous system has been reported, but peripheral nerve involvement (neurolymphomatosis [NL]) rarely has been described...
  21. doi Vascular leiomyosarcoma: Clinicopathology and immunohistochemistry with special reference to a unique smooth muscle phenotype
    Atsuji Matsuyama
    Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    Pathol Int 60:212-6. 2010
    ..These findings suggest that the vascular LMS displays a distinctive phenotype of smooth muscle differentiation according to histopathogenesis...
  22. doi Surgical challenges in the treatment of leiomyosarcoma of the inferior vena cava: analysis of two cases and brief review of the literature
    Maria A Kyriazi
    2nd Department of Surgery, Aretaieion Hospital, University of Athens Medical School, Athens, Greece
    Ann Vasc Surg 24:826.e13-7. 2010
    ..Optimal treatment should include complete resection of the malignant lesion with preservation of venous return. We present our experience from two patients treated in our hospital in the last 3 years...
  23. doi Recurrent pulmonary intimal sarcoma involving the right ventricular outflow tract
    Dipesh K Shah
    Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    Ann Thorac Surg 91:e41-2. 2011
    ..The sarcoma recurred in about 8 weeks. It responded favorably to chemoradiation therapy and shows some signs of regression...
  24. ncbi FDG imaging of a pulmonary artery sarcoma
    R L Thurer
    Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann Thorac Surg 70:1414-5. 2000
    ..Based on preoperative imaging and intraoperative findings, a right pneumonectomy was performed for what proved to be a pulmonary artery sarcoma...
  25. ncbi Primary pulmonary artery sarcoma: report of three cases and review of the literature
    Luis Manso
    Department of Medical Oncology, University Hospital 12 de Octubre, Madrid, Spain
    Clin Lung Cancer 8:277-81. 2007
    ..The mean survival time ranges from 14 months to 18 months. We report 3 cases of PAS treated with surgery and chemotherapy (anthracyclines and ifosfamide) with different outcomes...
  26. doi Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases
    A Gaumann
    Institute of Pathology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042, Regensburg, Germany
    Virchows Arch 453:473-84. 2008
    ..Despite myofibroblastic phenotype, APC/beta-catenin pathway changes are rare. Cyclin D1, only expressed in the myxofibrosarcoma-type, is likely transcribed via factors other than beta-catenin...
  27. doi Presentation of pulmonary artery intimal sarcoma in an infant with a history of neonatal valvular pulmonic stenosis
    Tresa Chappell
    Department of Pediatrics, Vanderbilt Children s Hospital, Nashville, Tennessee, USA
    Ann Thorac Surg 85:1092-4. 2008
    ..It is usually diagnosed postmortem in patients thought to have pulmonary emboli. We present a case of intimal sarcoma of the pulmonary artery in an infant with a history of neonatal pulmonic stenosis...
  28. doi Early diagnosis and resection of an asymptomatic leiomyosarcoma of the inferior vena cava prior to caval obstruction
    Fabio Ramponi
    Department of Vascular Surgery, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia
    J Vasc Surg 55:525-8. 2012
    ..In this case report, we describe an asymptomatic intraluminal leiomyosarcoma of the inferior vena cava diagnosed incidentally prior to caval occlusion during a routine ultrasound examination of the upper abdomen...
  29. ncbi Pulmonary artery angiosarcoma: a clinicopathologic and radiological correlation
    Lei Huo
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Ann Diagn Pathol 9:209-14. 2005
    ..The tumor cells were positive for CD31 and vimentin and negative for pan-cytokeratin, CD34, and S100. Two months after surgery, the patient was alive and well...
  30. ncbi Spontaneous vascular neoplasms in aged Sprague-Dawley rats
    G M Zwicker
    Toxicology Department, Dow Chemical Company, Health and Environmental Sciences, Indianapolis, Indiana 46268, USA
    Toxicol Pathol 23:518-26. 1995
    Primary benign and malignant vascular neoplasms occurred spontaneously in 8 of 710 male (1.1%) and 4 of 710 female (0...
  31. pmc Leiomyosarcoma of the inferior vena cava: experience in 22 cases
    Edouard Kieffer
    Department of Vascular Surgery, Pitie Salpetriere University Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Ann Surg 244:289-95. 2006
    ..Although surgical resection combined with chemotherapy is usually not curative, it can achieve reasonably long-term survival. We recommend aggressive operative management using the latest vascular surgery and oncology techniques...
  32. ncbi Intimal angiosarcoma of the aorta: report of a case and review of the literature
    Andreas Thalheimer
    Department of Vascular Surgery, University of Wuerzburg, Germany
    J Vasc Surg 40:548-53. 2004
    ....
  33. ncbi Intravenous leiomyomatosis with extension to the heart: echocardiographic features: a case report
    Ber Ren Fang
    Division of Cardiology, Chang Gung Memorial Hospital, and Chang Gung University, College of Medicine, Taiwan, Republic of China
    Angiology 58:376-9. 2007
    ..She recovered well. Repeat magnetic resonance imaging 6 months following the second operation showed that the inferior vena cava and right atrium were clear of tumor...
  34. ncbi Pulmonary artery sarcoma: a clinicopathologic and immunohistochemical study of 12 cases
    Lei Huo
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston 77030 4009, USA
    Am J Clin Pathol 125:419-24. 2006
    ..Pulmonary artery sarcoma is an uncommon entity with a poor prognosis. The role of early diagnosis, histologic classification, surgical treatment, and adjuvant therapy in patient outcome is discussed...
  35. ncbi Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice
    Elena Kleymenova
    CIIT Centers for Health Research, 6 Davis Drive, Research Triangle Park, NC, 27709, USA
    Carcinogenesis 25:309-15. 2004
    ....
  36. ncbi Successful treatment of pulmonary artery sarcoma by a two-drug combination chemotherapy consisting of ifosfamide and epirubicin
    Akiko Uchida
    Department of Hematology, Oncology and Respiratory Medicine Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Jpn J Clin Oncol 35:417-9. 2005
    ..Surgical resection is currently the most hopeful treatment for pulmonary artery sarcoma. However, intensive chemotherapy is worth trying in unresectable patients...
  37. ncbi Intimal sarcoma of the descending aorta
    Shapour Shirani
    Department of Radiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 10:253-4. 2007
    ..Magnetic resonance imaging also showed an irregular tumor (invasion to the left main bronchus). This case emphasizes the need for a wide panel of immunohistochemical studies in tumor emboli of unknown origin...
  38. ncbi Intimal sarcoma of the thoracic aorta; clinical-course and autopsy finding
    Kenji Akiyama
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    Ann Thorac Cardiovasc Surg 11:135-8. 2005
    ..The pathological finding was of a primary intimal sarcoma. The patient lived for more than two years excluding the hospitalized period after the diagnosis...
  39. ncbi Epithelioid hemangioendothelioma of the radial artery
    Patrizio Castelli
    Postgraduate School in Vascular Surgery, Department of Surgery, University of Insubria, 21100, Varese, Italy
    J Vasc Surg 41:151-4. 2005
    ..He had a complete resection of the tumor and of the segment of radial artery involved. The histologic examination revealed an intravascular EHE, with low mitotic index and with insufficient histologic anormalities...
  40. ncbi Clinical results of surgery for retroperitoneal sarcoma with major blood vessel involvement
    Matthias H M Schwarzbach
    Department of Surgery, University of Heidelberg, Heidelberg, Germany
    J Vasc Surg 44:46-55. 2006
    ..The study was conducted to evaluate the clinical results of resection for retroperitoneal soft tissue sarcoma (STS) with vascular involvement...
  41. ncbi Leiomyosarcoma of the inferior vena cava: survival after aggressive management
    Hiromichi Ito
    Department of Surgery, Brigham and Women s Hospital, Dana Farber Cancer Institute, and Harvard Medical School, Boston, MA, USA
    Ann Surg Oncol 14:3534-41. 2007
    ..Leiomyosarcoma (LMS) of the inferior vena cava (IVC) is exceedingly rare. The role of adjuvant therapy remains undefined. This study evaluated outcomes after aggressive management...
  42. doi A case of intravenous leiomyomatosis with high levels of hyaluronan
    Chizuko Yaguchi
    Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamastu, Shizuoka, 433 3192, Japan
    J Obstet Gynaecol Res 36:454-8. 2010
    ..IVL has viscoelastic properties and contains a large amount of hyaluronan, which may promote invasion during pathogenesis...
  43. doi Intravenous leiomyomatosis with intracardiac extension: a report of two cases
    Lei Yu
    Department of Cardiac Surgery, The First Affiliated Hospital, China Medical University, Shenyang, PR China
    J Card Surg 26:56-60. 2011
    ..In this report, we describe two women with leiomyomatosis originating from the uterus and extending into the inferior vena cava to the right ventricle that was successfully resected using a two-stage approach. ..
  44. ncbi Leiomyosarcoma of the inferior vena cava
    Meltem Ceyhan
    Department of Radiology, Ondokuz Mayis University School of Medicine, Samsun, Turkey
    Diagn Interv Radiol 13:140-3. 2007
    ..We present a case of leiomyosarcoma of the inferior vena cava that extended into the right renal vein and the right iliac vein, as it is a rare case and emphasize the significance of the imaging methods in its diagnosis...
  45. doi Primary leiomyosarcoma of the inferior vena cava: reports of infrarenal and suprahepatic caval involvement
    Michael N Tameo
    Section of Vascular Surgery, Pennsylvania Hospital, Philadelphia, PA, USA
    J Vasc Surg 51:221-4. 2010
    ..A review of this rare tumor is presented...
  46. doi The rupture of descending thoracic aorta due to the necrosis of aortic intimal sarcoma
    Mutsuo Tanaka
    Department of Cardiovascular Surgery, Sakakibara Heart Institute, Fuchu si, Tokyo, Japan
    Interact Cardiovasc Thorac Surg 10:462-3. 2010
    ..The patient developed a local recurrence and abdominal dissemination of the tumor three months after surgery. We report the case and discuss about the diagnosis and treatment of thoracic aortic intimal sarcoma...
  47. doi Intravenous leiomyomatosis of the uterus: a clinicopathologic study of 18 cases, with emphasis on early diagnosis and appropriate treatment strategies
    Jing Du
    Department of Pathology, Tianjin Cancer Hospital, Tianjin Medical, University, Tianjin 300070, PR China
    Hum Pathol 42:1240-6. 2011
    ..It is important to adequately sample all uterine leiomyomas and carefully examine the soft tissue on either side of the lower uterine segment below the peritoneal reflection to identify early-stage intravenous leiomyomatosis...
  48. ncbi Intimal-type primary sarcoma of the thoracic aorta: an unusual case presenting with left arm embolization
    Giulio Pompilio
    Department of Cardiovascular Surgery, University of Milan, Centro Cardiologico Monzino Foundation IRCCS, Via Parea 4, 20138 Milano, Italy
    Eur J Cardiothorac Surg 21:574-6. 2002
    ..A case of intimal-type primary sarcoma of the thoracic aorta with unusual left arm embolization is reported...
  49. doi Liver resection with portal vein thrombectomy for hepatocellular carcinoma with vascular invasion
    Luca Aldrighetti
    Department of Surgery Liver Unit, Scientific Institute San Raffaele, Vita Salute San Raffaele University, Milan, Italy
    Ann Surg Oncol 16:1254. 2009
    ..In surgically resected series, in patients with gross PVTT (PVTT in the portal trunk, its first-order branch, or its second-order branch), the 3-year and 5-year survival rates are reportedly 15% to 28% and 0% to 17%, respectively...
  50. ncbi Primary intravascular myxoid leiomyosarcoma of the femoral vein presenting clinically as deep vein thrombosis: a case report
    Manish Mani Subramaniam
    Virchows Arch 450:235-7. 2007
  51. ncbi From the archives of the AFIP: primary vascular neoplasms of the spleen: radiologic-pathologic correlation
    Robert M Abbott
    Radiographics 24:1137-63. 2004
    Primary vascular neoplasms of the spleen constitute the majority of nonhematolymphoid splenic tumors...
  52. ncbi Should the inferior vena cava be reconstructed after resection for malignant tumors?
    Hiroyuki Yoshidome
    Department of General Surgery, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 0856 Japan
    Am J Surg 189:419-24. 2005
    ..Caval replacement after circumferential resection of the inferior vena cava remains controversial. The aim of the current study is to determine whether or not inferior vena cava replacement should be performed...
  53. pmc Intravascular leiomyosarcoma of the brachiocephalic region -- report of an unusual tumour localisation: case report and review of the literature
    Daniel Johannes Tilkorn
    Department of Plastic Surgery, Burn Center, Hand Center, Sarcoma Reference Center, BG University Hospital Bergmannsheil, Ruhr University Bochum, Germany
    World J Surg Oncol 6:113. 2008
    ..Intravascular leiomyosarcoma is a rare tumour entity originating from venous vessel structures and most frequently affecting the inferior vena cava...
  54. ncbi Surgical treatment and outcomes of patients with primary inferior vena cava leiomyosarcoma
    Scott T Hollenbeck
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Am Coll Surg 197:575-9. 2003
    ..The inferior vena cava (IVC) is a rare site for primary soft tissue sarcoma. There are limited data in the literature regarding surgical management of the IVC and longterm survival of these patients...
  55. ncbi Primary vascular leiomyosarcoma of the femoral vein leading to metastases of scalp and lungs
    C H Gow
    Clin Oncol (R Coll Radiol) 17:201. 2005
  56. ncbi Leiomyosarcoma of the ovarian vein: report of a case
    Antonio Iannelli
    Department of Liver Transplantation, Gastrointestinal and Laparoscopic Surgery, Archet 2 Hospital, Nice, France
    Int Surg 88:6-8. 2003
    ..The patient underwent radical en bloc extirpation of the tumor followed by radiation therapy. The clinicopathologic features and treatment are discussed...
  57. ncbi Leiomyosarcoma of the pulmonary vein
    T Okuno
    Laboratory of Anatomic Pathology, Kyoto University Hospital, Japan
    Pathol Int 50:839-46. 2000
    ..The present case was the oldest in age and to our knowledge was the first reported case with metastasis in a distant lymph node...
  58. ncbi Leiomyosarcoma of the inferior vena cava: surgical management and clinical results
    Jason Dew
    Wake Forest University School of Medicine, Department of Surgery, Surgical Oncology, Vascular Surgery Service, Winston Salem, North Carolina 27157, USA
    Am Surg 71:497-501. 2005
    ..The management of the IVC can be managed with primary repair, ligation, or prosthetic graft. Long-term survival is possible if complete resection can be achieved...
  59. ncbi A case of leiomyosarcoma originating from pulmonary vein, occluding mitral inflow
    Ali Gurbuz
    Ataturk Education and Research Hospital, Department of Cardiovascular Surgery, Izmir, Turkey
    Heart Lung 32:210-4. 2003
    ..The tumor was totally removed. Open heart surgery is the acceptable approach for the management of intracardiac tumors, which may cause obstruction of blood flow through the heart...
  60. ncbi Unusual pulmonary lesions: case 3. Pulmonary vein leiomyosarcoma presenting as a left atrial mass
    Sandeep T Laroia
    University of North Dakota, Veterans Affairs Medical Center, and MeritCare Medical Center, Fargo, ND, USA
    J Clin Oncol 20:2749-51. 2002
  61. ncbi Prosthetic replacement of the infrahepatic inferior vena cava for leiomyosarcoma
    Giulio Illuminati
    The Francesco Durante Department of Surgery, University of Rome La Sapienza, Rome, Italy
    Arch Surg 141:919-24; discussion 924. 2006
    ..Resection of the infrahepatic inferior vena cava associated with prosthetic graft replacement for caval leiomyosarcoma is an acceptable procedure to obtain prolonged and good-quality survival...
  62. ncbi Leiomyosarcoma of the inferior vena cava
    Venkataprasanth P Reddy
    Department of Internal Medicine, Kansas University Medical Center, Kansas City, KS 66160, USA
    Clin Nucl Med 31:281-3. 2006
  63. ncbi Primary leiomyosarcoma of inferior vena cava, a rare entity: Imaging features
    D Hemant
    Departments of Radiology and Pathology, King Edward Memorial Hospital, Parel, Mumbai 400#012, India
    Australas Radiol 45:448-51. 2001
    ..Cavography was useful to evaluate the collateral circulation associated with the extensive intraluminal mass. The lesion was biopsied under ultrasound guidance...
  64. ncbi One case of leiomyosarcoma of the inferior vena cava treated with radical resection and vascular reconstruction
    Zhou Jun Shen
    Department of Urology, 1st Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, China
    Vasc Med 10:225-7. 2005
    ..A 48-year-old Chinese woman with primary leiomyosarcoma of the inferior vena cava (IVC) who succesfully underwent resection of a long length of the affected IVC and the right kidney together with graft replacement of the IVC is reported...
  65. ncbi [Intravascular leiomyomatosis: the surgical challenge of tumors with cavoatrial extension]
    José M Vallejo
    Rev Esp Cardiol 58:1246-7. 2005
  66. ncbi Kidney tumour mimicking cardiac mass
    Juan M Nogales Asensio
    Int J Cardiol 106:401-3. 2006
    ..It is also exceptional that this was a chance finding in an asymptomatic patient...
  67. ncbi Intravenous uterine leiomyomatosis with right heart extension: successful two-stage surgical removal
    Patrizio Castelli
    Vascular Surgery, Department of Surgery, University of Insubria, Varese, Italy
    Ann Vasc Surg 20:405-7. 2006
    ..We report a case of a young woman with intravenous leiomyomatosis originating from the uterus and extending into the right atrium, successfully treated through a two-stage surgical approach...
  68. ncbi Tumor thrombectomy without bypass for low-grade malignant tumors extending into the inferior vena cava: report of two cases
    Masatoshi Jibiki
    Department of Vascular and Applied Surgery, Tokyo Medical and Dental University, Graduate School, 1 5 45 Yushima, Tokyo, 113 8519, Japan
    Surg Today 36:465-9. 2006
    ..Aggressive surgical treatment is thus recommended to excise a tumor thrombus with or without an IVC resection in patients with ESS of low-grade malignancy extending into the IVC to prevent sudden death due to PE...
  69. ncbi Magnetic resonance venogram of intravenous leiomyomatosis
    T K K Lai
    Department of Radiology, Tseung Kwan O Hospital, Hong Kong
    Hong Kong Med J 11:524-6. 2005
  70. ncbi Cavo-atrial tumor resection under total circulatory arrest without a sternotomy
    Thomas Kleisli
    Division of Cardiothoracic Surgery, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Ann Thorac Surg 81:1887-8. 2006
    ..This minimal-access total circulatory approach has the potential to greatly diminish morbidity when managing tumors of the inferior vena cava...
  71. ncbi [Effectiveness of multislice computed tomography for evaluating vascular invasion in retroperitoneal tumors]
    I E Tiurin
    Vopr Onkol 54:65-9. 2008
    ..Multislice scans were obtained by using 4 rows of solid-state detectors. For intravenous injections, non-ionic contrasting substance Omniak (loxegol, Amersham, Ireland), 350 mg I/ml was used...
  72. ncbi Primary leiomyosarcoma of the pulmonary artery: Is aggressive treatment justified for a long survival?
    Kalliopi Athanassiadi
    Department of Thoracic and Cardiovascular Surgery, Medical School of Hannover, Hannover, Germany
    J Thorac Cardiovasc Surg 132:435-6. 2006
  73. ncbi Leiomyosarcoma of the inferior vena cava
    A Bonura
    Department of Radiology, Liverpool Hospital, Sydney, New South Wales, Australia
    Australas Radiol 50:395-9. 2006
    ..The clinical and imaging features are outlined, and in addition the treatment and prognosis...
  74. doi Surgical treatment for recurrent pulmonary artery sarcoma
    Atsushi Omura
    Department of Cardiovascular Surgery, Sumitomo Hospital, 5 3 20 Nakanoshima, Kita ku, Osaka, Osaka, 530 0005, Japan
    Gen Thorac Cardiovasc Surg 56:28-31. 2008
    ..Postoperative right cardiac catheterization indicated hemodynamic improvement and no sign of stenosis around the RVOT. About 1 year postoperatively, she is in stable condition and has 5-year-survival from the initial operation...
  75. ncbi [Establishment of renal cell carcinoma metastasis in the inferior vena cava and in the right atrium]
    H Kachler
    Dtsch Med Wochenschr 132:1219-20. 2007
  76. ncbi Bleeding sarcoma of the aorta mimicking a symptomatic aneurysm
    Bart P Van Putte
    Department of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, The Netherlands
    J Thorac Cardiovasc Surg 133:1643-4. 2007
  77. ncbi Osteosarcoma of the lumbosacral spine invading the central venous pathways, right-sided cardiac chambers, and pulmonary artery
    Neely Hines
    Department of Radiology, Jacobi Medical Center Albert Einstein College of Medicine, 1400 Pelham Parkway South, Bronx, NY 10461, USA
    Skeletal Radiol 36:1091-6. 2007
    ..There is only one other reported case of direct extension into the venous system by an iliac bone osteosarcoma in an adolescent; however, the tumor did not extend into the pulmonary circulation...
  78. doi [Leiomyosarcoma of the inferior vena cava. Diagnosis using endoscopic ultrasound-guided fine-needle aspiration biopsy]
    C Jenssen
    Klinik fur Innere Medizin, Krankenhaus Märkisch Oderland, Prötzeler Chaussee 5, 15331 Strausberg
    Dtsch Med Wochenschr 133:769-72. 2008
    ..A 75-year-old woman was admitted because of upper abdominal pain, nausea and vomiting...
  79. ncbi [Tumor thrombectomy for endometrial stromal sarcoma extending into the inferior vena cava and the right atrium from the uterus]
    Shigemasa Suzuki
    Department of Cardiovascular Surgery, Isesaki Munisipal Hosital, Isesaki, Japan
    Kyobu Geka 61:139-42. 2008
    ..After thrombectomy, she underwent chemotherapy with carboplatin and paclitaxel. Surgical resection and chemotherapy to low-grade ESS achieved favourable prognosis...
  80. pmc Leiomyosarcoma of the adrenal vein: a novel approach to surgical resection
    Tracy S Wang
    Department of Surgery, Section of Endocrine Surgery, Yale University School of Medicine, New Haven, Connecticut, USA
    World J Surg Oncol 5:109. 2007
    ..Leiomyosarcomas arising from the adrenal vein are rare malignancies associated with delayed diagnosis and poor prognosis. The most common vascular site of origin is the inferior vena cava...
  81. ncbi Primary malignant sarcomas of the heart and great vessels in adult patients--a single-center experience
    Frank Mayer
    Department of Medical Oncology Hematology Immunology Rheumatology Pulmonology, UKT Medical Center, South West German Cancer Center, Eberhard Karls University Tuebingen, Otfried Mueller Str 10, 72076 Tuebingen, Germany
    Oncologist 12:1134-42. 2007
    ..Sarcomas arising in the heart or the great vessels are rare entities. The prognosis of the patients is dismal...
  82. ncbi [Ascitis in 54-year old male]
    A Arévalo Gómez
    Servicio de Medicina Interna D, Hospital Abente y Lago, Complejo Hospitalario Juan Canalejo, A Coruna, Spain
    Rev Clin Esp 208:253-4. 2008
  83. ncbi Retroperitoneal leiomyosarcoma of the inferior vena cava mimicking a liver tumor
    Julio Sokolich
    Department of Surgery, Methodist Dallas Medical Center, Dallas, Texas 75265 5999, USA
    Am Surg 74:433-6. 2008
    ..Considering the aggressiveness of this tumor, early radical en block resection with clear margins is still the only chance for long-term survival...
  84. ncbi Surgical treatment of renal cell carcinoma with right atrial thrombus: early experience and description of a simplified technique
    T Modine
    Service de chirurgie cardiovasculaire, Pr H Warembourg, Hopital Cardiologique, Bd J Leclerc, CHRU de Lille, France
    Int J Surg 5:305-10. 2007
    ..Minimally invasive CPB technique can be used to treat intra atrial thrombus tumor extension arising from renal cell carcinoma. It can be performed safely with acceptable complications rate...
  85. ncbi Liver hanging maneuver for large or recurrent right upper quadrant tumors
    Matteo Donadon
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Am Coll Surg 204:329-33. 2007
  86. ncbi Therapy insight: malignant primary cardiac tumors
    Michael J Reardon
    Methodist DeBakey Heart Center, Houston, TX 77030, USA
    Nat Clin Pract Cardiovasc Med 3:548-53. 2006
    ..Surgical resection of this sarcoma type often requires pneumonectomy and can require pulmonary root replacement...
  87. ncbi [Leiomyosarcoma of the inferior vena cava]
    D Kotelis
    Abteilung für Gefässchirurgie, Chirurgische Universitatsklinik, Ruprecht Karls Universitat Heidelberg, 69120 Heidelberg, Deutschland
    Chirurg 78:469-70, 472-3. 2007
    ..Following elaborate preoperative examinations, surgical resection was performed and the inferior vena cava was reconstructed. Clinical signs, diagnosis, therapy, and prognosis are discussed...
  88. ncbi Leiomyosarcoma of the uterus with intravascular tumor extension and pulmonary tumor embolism
    Douglas K McDonald
    Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
    Cardiovasc Intervent Radiol 30:140-2. 2007
    ..To our knowledge, only two other cases of intravenous uterine leiomyosarcomatosis have been described in the existing literature, and this is the first reported case of the entity with associated intravascular tumor embolism...
  89. ncbi [Extrarenal parametrial angiomyolipoma of the ovarian vein with extension into the right atrium]
    M Daneschnejad
    Rofo 179:166-7. 2007
  90. ncbi Intravenous leiomyomatosis extending from the inferior caval vein to the pulmonary artery
    Giuseppe Virzí
    First Department of Surgery, Ospedale Vittorio Emanuele, Catania, Italy
    J Thorac Cardiovasc Surg 133:831-2. 2007
  91. ncbi A 39-year-old woman with cough, chest pressure, and worsening dyspnea
    Jesse A Pewarchuk
    Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Chest 131:934-7. 2007
  92. ncbi Surgery of inferior vena cava associated malignant tumor lesions
    F Eder
    Department of General, Abdominal and Vascular Surgery, University Hospital, Magdeburg, Germany
    Vasa 37:68-80. 2008
    ....
  93. ncbi Pulmonary artery sarcoma and chronic thromboembolism
    Simone G Ramos
    Department of Pathology, Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Av Bandeirantes 3900, 14049 900 Ribeirao Preto, SP, Brazil
    Pathol Res Pract 204:139-41. 2008
    ..Partial improvement after thrombolytic therapy has suggested that thromboembolic phenomena may be superimposed on the tumor, but, to date, a well-documented statement of these events has not been provided...
  94. ncbi Surgery for retroperitoneal sarcoma requiring major vascular resection and reconstruction
    Melissa C C Teo
    Department of General Surgery, Singapore General Hospital, Singapore
    Asian J Surg 28:312-5. 2005
    ..This paper describes a series of these tumours and demonstrates the feasibility of radical surgery and resection of major vessels with low morbidity...
  95. ncbi Leiomyosarcoma of the inferior vena cava: three case reports and review of the literature
    Nicholaus J Hilliard
    Department of Pathology at University of Alabama at Birmingham, Birmingham, AL 35233 6823, USA
    Ann Diagn Pathol 9:259-66. 2005
    ....
  96. ncbi Leiomyosarcoma of the uterus with a florid intravascular component ("intravenous leiomyosarcomatosis")
    Kathleen C M Coard
    Department of Pathology, University of the West Indies, Mona, Kingston, Jamaica
    Int J Gynecol Pathol 21:182-5. 2002
    ..To our knowledge, this is the first reported such case in the literature, for which we propose the designation intravenous leiomyosarcomatosis of the uterus...
  97. ncbi [Case report: Pedunculated leiomyosarcoma of the inferior vena cava]
    Nazan Okur
    Cukurova Universitesi Tip Fakultesi, Radyodiagnostik Anabilim Dali, Adana
    Tani Girisim Radyol 9:78-80. 2003
    ..She was operated on and the tumor was discovered to be attached to the wall of the inferior vena cava with a peduncle, a leiomyosarcoma being proven histologically. CT features of this rare tumor are presented in this report...
  98. ncbi [Diagnostic imaging of vascular leiomyosarcomas]
    B Kreft
    Radiologische Klinik, Universitat Bonn
    Rofo 176:183-90. 2004
    ..MRI with MR-angiography can be added. If a tumor of undetermined origin shows a broad contact with a vessel and/or an intraluminal component, possible primary vascular leiomyosarcoma should be included in the differential diagnosis...
  99. ncbi [Intravenous leiomyomatosis extending into the right atrium from a myoma of the uterus]
    Makoto Sasaki
    Department of Internal Medicine, Saiseikai Utsunomiya Hospital, Tochigi
    Nihon Naika Gakkai Zasshi 93:142-4. 2004
  100. ncbi Failure of medical therapy for pulmonary "thromboembolic" disease: beware the unsuspected primary sarcoma of the pulmonary artery
    Cliff K Choong
    Department of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, One Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA
    J Thorac Cardiovasc Surg 128:763-5. 2004
  101. ncbi Intravenous leiomyoma with cardiac involvement
    C Anichini
    Department of Pathology, University of Florence, Florence, Italy
    Int Angiol 20:345-7. 2001
    ..Such a rare neoplastic condition most often arises from the uterine veins. At times it may reach the right cavities of the heart and it must be considered in the differential diagnosis with a cardiac myxoma or a thrombus...

Research Grants18

  1. Roles of Akt and immune regulation in the development of hemangiomas
    Thuy Phung; Fiscal Year: 2007
    ..our understanding of how endothelial cell behavior is regulated, and help us better understand other vascular neoplasms, such as hemangioendothelioma and angiosarcoma, and open new therapeutic options in the treatment of ..
  2. Mechanisms of Scar-Free Healing in the Fetal Artery
    DARRELL CASS; Fiscal Year: 2007
    ..His long term objective is to apply this knowledge clinically in both children and adults to limit vascular inflammation, neointimal hyperplasia and scarring. ..
  3. Negative Regulation of VEGF-Mediated Angiogenesis
    Sandra W Ryeom; Fiscal Year: 2010
    ..These studies will establish whether Dscr1 is a valid target for anti-cancer intervention which may lead to novel therapeutic strategies for suppressing tumor angiogenesis in all cancers. ..
  4. Cellular and Molecular Mechanisms of Vascular Remodeling
    Josephine Enciso; Fiscal Year: 2007
    ..abstract_text> ..
  5. Role of Obscurin and Obscurin-MLCK in myofibrillogenesis
    Mark Russell; Fiscal Year: 2007
    ..Characterizing obscurin's roles in new myofibril assembly and in sarcomere-sarcoplasma organization may identify new strategies to treat congestive heart failure and prevent myofibril damage during ischemia. ..
  6. CLONING OF A POTENTIAL REGULATOR OF THE DHAND FACTOR
    Mark Russell; Fiscal Year: 2002
    ....
  7. Molecular mechanisms of choroidal neovascularization and vascular homeostasis
    ALEXANDER GEORG MARNEROS; Fiscal Year: 2010
    ..These findings are likely to reveal novel molecular targets for the treatment of neovascular age-related macular degeneration. ..