Genomes and Genes
Summary: Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.
Publications248 found, 100 shown here
- Preventing amputation in older adults with diabetesLaurie Umeh
Kaiser Continuing Care Services, Richmond, California, USA
Adv Nurse Pract 14:41-3, 70. 2006
- Maggots 'n' chips: a novel approach to the treatment of diabetic ulcersAngela Lodge
Br J Community Nurs 11:suppl 23-6. 2006
- What are the most effective interventions in preventing diabetic foot ulcers?Lawrence A Lavery
Texas A and M Health Science Center, Scott and White Hospital, Temple, TX, USA
Int Wound J 5:425-33. 2008..These results suggest that there is a finite number of key factors that, if identified and addressed with appropriate intervention strategies, may reduce the risk for the cascade of events towards ulceration and subsequent amputation...
- Adiponectin, resistin and IL-6 plasma levels in subjects with diabetic foot and possible correlations with clinical variables and cardiovascular co-morbidityAntonino Tuttolomondo
Dipartimento Biomedico di Medicina Interna e Specialistica Università degli Studi di Palermo, Italy
Cardiovasc Diabetol 9:50. 2010It is very suggestive that diabetic foot is characterized by a pronounced inflammatory reaction and the pathogenic significance of this inflammation has received little attention...
- Using honey to heal diabetic foot ulcersP C Molan
Honey Research Unit, Department of Biological Sciences, University of Waikato, Hamilton, New Zealand
Adv Skin Wound Care 21:313-6. 2008
- Patient and professional perspectives on prescribed therapeutic footwear for people with diabetes: a vignette studyMaxine Johnson
School of Health and Related Research, University of Sheffield, Sheffield, UK
Patient Educ Couns 64:167-72. 2006..This article draws on a qualitative study to identify and discuss patient and health professional views of the use of therapeutic footwear for people with diabetes-related foot complications...
- Challenges for management of the diabetic foot in Africa: doing more with lessZulfiqarali G Abbas
Department of Internal Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
Int Wound J 4:305-13. 2007..Gangrene and infections are two of the more serious sequelae of diabetic foot ulcer disease that cause long-standing disability, loss of income, amputation or death...
- Profile of diabetic foot complications and its associated complications--a multicentric study from IndiaV Viswanathan
Diabetes Research Centre, Chennai
J Assoc Physicians India 53:933-6. 2005..Neuropathy (15%) was found to be an important risk factor for diabetic foot infections...
- Maggot debridement therapy with Lucilia cuprina: a comparison with conventional debridement in diabetic foot ulcersAaron G Paul
Department of Orthopaedic Surgery, Sarawak General Hospital, Sarawak, Malaysia
Int Wound J 6:39-46. 2009..therapy (MDT) with the sterile larvae of Lucilia cuprina (a tropical blowfly maggot) for the treatment of diabetic foot ulcers. Literature thus far has only reported results with the temperate maggot, Lucilia sericata...
- Knowledge and practice of foot care in people with diabetesR D Pollock
Diabetes Research Group and Life Course and Paediatric Research Group, School of Clinical Medical Sciences, Medical School, Framlington Place, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK
Diabetes Res Clin Pract 64:117-22. 2004..5) and their foot care practise was better. CONCLUSION: The results highlight areas where efforts to improve knowledge and practice may contribute to the prevention of foot ulcers and amputation...
- Admission trends over 8 years for diabetic foot ulceration in a specialized diabetes unit in cameroonAndre Pascal Kengne
The George Institute for International Health, The University of Sydney, Australia
Int J Low Extrem Wounds 8:180-6. 2009..With one exception, the amputation rate of 16% (95% CI = 11%-20%) was similar across years. Foot ulcer is a major cause of hospital admission and bed use for diabetes in Cameroon...
- Developing and validating a risk score for lower-extremity amputation in patients hospitalized for a diabetic foot infectionBenjamin A Lipsky
Department of Medicine, University of Washington, Seattle, WA, USA
Diabetes Care 34:1695-700. 2011b>Diabetic foot infection is the predominant predisposing factor to nontraumatic lower-extremity amputation (LEA), but few studies have investigated which specific risk factors are most associated with LEA...
- Diabetic foot infection: usefulness of SPECT/CT for 99mTc-HMPAO-labeled leukocyte imagingLuca Filippi
Section of Nuclear Medicine, Ospedale Maggiore, Trieste, Italy
J Nucl Med 50:1042-6. 2009Our aim was to evaluate the role of SPECT/CT for the diagnosis of diabetic foot infection by labeled leukocytes.
- Regional differences in risk factors and clinical presentation of diabetic foot lesionsS Morbach
Diabetic Foot Clinic, Department of Internal Medicine, Marienkrankenhaus Soest, Germany
Diabet Med 21:91-5. 2004Problems associated with the diabetic foot are worldwide. However, there may be regional variation among risk factors and clinical presentation. Prospective comparative data concerning this topic are rare.
- Influence of bioengineered skin substitutes on diabetic foot ulcer and venous leg ulcer outcomesC Barber
ASERNIP S, Royal Australasian College of Surgeons, Stepney, Australia
J Wound Care 17:517-27. 2008..systematic review indicates that bioengineered skin substitutes with a dermal component may improve healing outcomes in diabetic foot ulcers and venous leg ulcers. However, better designed trials with longer follow-up periods are needed.
- Physician attitudes toward foot care education and foot examination and their correlation with patient practiceGiorgia De Berardis
Diabetes Care 27:286-7. 2004
- Can the use of a topical antifungal nail lacquer reduce risk for diabetic foot ulceration? Results from a randomised controlled pilot studyDavid G Armstrong
Scholl s Center for Lower Extremity Ambulatory Research CLEAR at Rosalind Franklin University of Medicine, 3333 Green Bay Road, Chicago, IL 60064, USA
Int Wound J 2:166-70. 2005..In this randomised controlled trial, 70 persons at high risk for diabetic foot ulceration were enrolled into a preventative care program involving daily self-inspection with the possible ..
- Psychosocial and behavioral aspects of diabetic foot lesionsLoretta Vileikyte
Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, United Kingdom
Curr Diab Rep 8:119-25. 2008This article reviews key findings from recently conducted and ongoing studies into how patients adapt to diabetic foot complications by focusing on two areas...
- Matrix metalloproteinases and diabetic foot ulcers: the ratio of MMP-1 to TIMP-1 is a predictor of wound healingM Muller
Department of Nephrology and Endocrinology, University Hospital, Grenoble, France
Diabet Med 25:419-26. 2008..In diabetic foot ulcers there is an excess of MMPs and a decrease of the tissue inhibitors of MMPs (TIMPs)...
- Assessment and treatment of diabetic foot ulcerA Shojaie Fard
Department of Surgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
Int J Clin Pract 61:1931-8. 2007..A critical triad of neuropathy, minor foot trauma and foot deformity was found in > 63% of diabetic foot ulcers (DFU). Peripheral vascular disease (PVD) has been identified in 30% of foot ulcers...
- Epidermal growth factor intralesional infiltrations can prevent amputation in patients with advanced diabetic foot woundsJorge Berlanga Acosta
Division of Pharmaceutics, Center for Genetic Engineering and Biotechnology, Havana City, Cuba
Int Wound J 3:232-9. 2006..5 +/- 4.9 days. Wound recurrence after 1 year of follow-up appeared in only one patient. Preliminary evidences suggest that EGF intralesional infiltrations may be effective in reducing diabetic lower limb amputation...
- Hyperbaric oxygen as an intervention for managing wound hypoxia: its role and usefulness in diabetic foot woundsMichael B Strauss
Department of Hyperbaric Medicine, Long Beach Memorial Medical Center, 2801 Atlantic Avenue, PO Box 1428, Long Beach, CA 90801 1428, USA
Foot Ankle Int 26:15-8. 2005..This article discusses the role of HBO as an adjunct to the management of diabetic problem foot wounds from evidenced-based, approved (by Medicare) indications and cost-effectiveness perspectives...
- Survey of bacterial diversity in chronic wounds using pyrosequencing, DGGE, and full ribosome shotgun sequencingScot E Dowd
United States Department of Agriculture ARS Livestock Issues Research Unit, Lubbock, TX, USA
BMC Microbiol 8:43. 2008..gradient gel electrophoresis were utilized to survey the major populations of bacteria that occur in the pathogenic biofilms of three types of chronic wound types: diabetic foot ulcers (D), venous leg ulcers (V), and pressure ulcers (P).
- Psychological aspects of diabetic neuropathic foot complications: an overviewLoretta Vileikyte
University of Miami, FL, USA and University of Manchester, UK
Diabetes Metab Res Rev 20:S13-8. 2004....
- Diabetes foot self-care practices in the German populationSascha Schmidt
Hessian Institute of Nursing Research Frankfurt Main, University of Applied Sciences, Frankfurt am Main, Germany
J Clin Nurs 17:2920-6. 2008The object of this study was to find out which self-care activities patients with diabetes perform to prevent diabetic foot syndrome (DFS) and to look for differences between patient groups (diabetes education and foot at risk).
- Clinical profile and management outcome of diabetic foot ulcers in a tertiary care hospitalKhalid Mehmood
Department of Medicine, Down University of Health Sciences and Civil Hospital, Karachi
J Coll Physicians Surg Pak 18:408-12. 2008To determine major risk factors and management outcome of diabetic foot ulcers in order to prevent amputation.
- Culture of percutaneous bone biopsy specimens for diagnosis of diabetic foot osteomyelitis: concordance with ulcer swab culturesEric Senneville
Diabetic Foot Clinic, Dron Hospital, Tourcoing, France
Clin Infect Dis 42:57-62. 2006We assessed the diagnostic value of swab cultures by comparing them with corresponding cultures of percutaneous bone biopsy specimens for patients with diabetic foot osteomyelitis.
- Initial report of the use of an injectable porcine collagen-derived matrix to stimulate healing of diabetic foot wounds in humansWilliam A Marston
Department of Surgery, University of North Carolina School of Medicine, Chapel Hill, 27599 7212, USA
Wound Repair Regen 13:243-7. 2005A novel injectable scaffolding matrix (E-Matrix) has been developed to accelerate wound healing in diabetic foot ulcers...
- A summary of guidelines for managing the diabetic footRobert G Frykberg
Podiatry Section, Carl T. Hayden VA Medical Center, Phoenix, AZ, USA
Adv Skin Wound Care 18:209-14. 2005
- Management of the diabetic foot: surgical and organisational aspectsF Gottrup
The University Center of Wound Healing, Odense University Hospital, Odense, Denmark
Horm Metab Res 37:69-75. 2005Most patients are older, but increasing numbers of young patients also develop diabetic foot ulcer (DFU). A third of the patients are under 50 years of age. The prevalence in the Western countries is 4-10% and the incidence 2-6%...
- MR imaging of the diabetic foot: diagnostic challengesDeep S Chatha
Department of Radiology, Hospital for Joint Diseases Orthopaedic Institute, 301 East 17th Street, New York, NY 10003, USA
Radiol Clin North Am 43:747-59, ix. 2005..The spectrum of diabetic foot infections is broad, ranging from callous and ulcer formation, to septic arthritis, abscess formation, and ..
- Polymicrobial nature of chronic diabetic foot ulcer biofilm infections determined using bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP)Scot E Dowd
Research and Testing Laboratory, Lubbock, Texas, USA
PLoS ONE 3:e3326. 2008..A primary impediment to the healing of chronic wounds is biofilm phenotype infections. Diabetic foot ulcers are the most common, disabling, and costly complications of diabetes...
- Selective primary angioplasty following an angiosome model of reperfusion in the treatment of Wagner 1-4 diabetic foot lesions: practice in a multidisciplinary diabetic limb serviceVlad Adrian Alexandrescu
Department of Surgery, Princesse Paola Hospital, Marche en Famenne, Belgium
J Endovasc Ther 15:580-93. 2008....
- Antioxidant and oxidative stress status in type 2 diabetes and diabetic foot ulcerElizabeth Bosede Bolajoko
Department of Chemical Pathology, University of Limpopo, Medunsa Campus, Garankuwa
S Afr Med J 98:614-7. 2008Oxidative stress (OS) has been implicated in the aetiology and progression of diabetic complications including diabetic foot ulcer...
- Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trialPeter A Blume
North American Center for Limb Preservation, 506 Blake St, New Haven, CT 06515, USA
Diabetes Care 31:631-6. 2008..The purpose of this study was to evaluate safety and clinical efficacy of negative pressure wound therapy (NPWT) compared with advanced moist wound therapy (AMWT) to treat foot ulcers in diabetic patients...
- Facility-level variations in patient-reported footcare knowledge sufficiency: implications for diabetes performance measurementMangala Rajan
Center for Healthcare Knowledge Management, Department of Veteran Affairs New Jersey Health Care System, East Orange, NJ, United States
Prim Care Diabetes 1:147-53. 2007..To evaluate medical center variation in self-reported knowledge of footcare practices by veterans at high risk for lower extremity complications...
- Role of magnetic resonance imaging in the evaluation of diabetic foot with suspected osteomyelitisU Rozzanigo
Diagnostic Imaging Unit, Carlo Poma Hospital, Viale Albertoni 1, 46100, Mantua, Italy
Radiol Med 114:121-32. 2009This study evaluated Magnetic Resonance Imaging (MRI) in infected diabetic foot ulcers.
- The diabetic foot: quality of lifePatricia Price
Wound Healing Research Unit, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom
Clin Infect Dis 39:S129-31. 2004..There are very few data on the life experiences of patients with infection and diabetic foot ulceration...
- Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan creamBenjamin A Lipsky
Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98116 1597, USA
Clin Infect Dis 47:1537-45. 2008Topical antimicrobial therapy of infected diabetic foot ulcers can focus on the wound and avoid the adverse effects of systemic anti-infective agents...
- Patients' perspectives on foot complications in type 2 diabetes: a qualitative studyLone Gale
Department of Social Medicine, University of Bristol, Horfield Health Centre, Bristol
Br J Gen Pract 58:555-63. 2008..Foot ulceration is a major health problem for people with diabetes. To minimise the risk of ulceration, patients are advised to perform preventive foot self-care...
- Comorbidities associated with diabetic foot complications among Asian Americans in southern CaliforniaPaul Y Han
Diabetic Foot Care Center, Coastal Communities Hospital, Tenet Health System, Santa Ana, CA 92704, USA
J Am Podiatr Med Assoc 93:37-41. 2003..The prevalence of diabetes mellitus in ethnic populations once considered practically exempt continues to rise steadily, and Asians living in the United States are becoming casualties of diabetes mellitus and its complications...
- Diabetes and bone: advantages and limitations of radiological, radionuclide and hybrid techniques in the assessment of diabetic footG Gnanasegaran
Department of Nuclear Medicine, Guys and St Thomas Hospital NHS Foundation Trust Hospital, London, UK
Minerva Endocrinol 34:237-54. 2009..In this review we discuss the efficacy of radiological and radionuclide techniques in the assessment of diabetic foot infection.
- Diabetic foot: evaluation and managementMelissa F Green
Department of Internal Medicine and the Comprehensive Diabetic Foot Clinic, University of South Alabama, Mobile, USA
South Med J 95:95-101. 2002b>Diabetic foot disease in the form of ulceration, charcot joint fracture, and amputation affects 20% of patients with diabetes. This results in tremendous morbidity, mortality, and health care cost...
- Significant J-shaped association between body mass index (BMI) and diabetic foot ulcersMin Woong Sohn
Center for Management of Complex Chronic Care, Hines VA Hospital, Hines, IL 60141 3030, USA
Diabetes Metab Res Rev 27:402-9. 2011..Disagreement exists regarding the relationship between body weight and foot ulceration risk among diabetic persons...
- Outcome of diabetic foot osteomyelitis treated nonsurgically: a retrospective cohort studyEric Senneville
Diabetic Foot Clinic, Dron Hospital, Tourcoing, France
Diabetes Care 31:637-42. 2008The purpose of this article was to identify criteria predictive of remission in nonsurgical treatment of diabetic foot osteomyelitis.
- A randomized, controlled trial of Promogran (a collagen/oxidized regenerated cellulose dressing) vs standard treatment in the management of diabetic foot ulcersAristidis Veves
Joslin Beth Israel Deaconess Foot Center, One Deaconess Rd, Boston, MA 02215, USA
Arch Surg 137:822-7. 2002..Promogran, a wound dressing consisting of collagen and oxidized regenerated cellulose, is more effective that standard care in treating chronic diabetic plantar ulcers...
- Management of patients hospitalized for diabetic foot infection: results of the French OPIDIA studyJ L Richard
Department of Diabetology and Nutritional Diseases, Caremeau University Hospital, place du Professeur Robert Debré, 30029 Nimes Cedex 9, France
Diabetes Metab 37:208-15. 2011This study was an analysis of how diabetic patients with infected foot wounds are managed in hospital by departments specializing in diabetic foot pathology, including an evaluation of the outcome 1 year after discharge.
- Is diabetic foot care efficacious or cost effective?D G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, 3601 South Sixth Avenue, Tucson, AZ 85723, USA
Ostomy Wound Manage 47:28-32. 2001..briefly evaluates literature that might support or refute the value of structured, regular care of the diabetic foot and wound...
- The effect of insulin and sulodexide (Vessel Due F) on diabetic foot syndrome: pilot study in elderly patientsT Koblik
Clinic of Metabolic Diseases, Jagiellonian University, Krakow, Poland
J Diabetes Complications 15:69-74. 2001..The ultimate validation of these preliminary results requires extensive trials...
- Diabetic foot infections: A need for innovative assessmentsTimothy K Fisher
University of Arizona, Tucson, 85724, USA
Int J Low Extrem Wounds 9:31-6. 2010..Adopting these advances in diagnosis and treatment may help with overall prognosis and reduce health care costs...
- Angiosomes and wound care in the diabetic footMark W Clemens
Department of Plastic Surgery, Georgetown University Medical Center, Washington, DC 20007, USA
Foot Ankle Clin 15:439-64. 2010..This article focuses on the surgical implications of angiosomes of the foot and ankle and their arterial-arterial connections...
- Depression and incident diabetic foot ulcers: a prospective cohort studyLISA H WILLIAMS
Department of Medicine, Division of Dermatology, University of Washington, Seattle, Wash, USA
Am J Med 123:748-754.e3. 2010To test whether depression is associated with an increased risk of incident diabetic foot ulcers.
- Management of a diabetic foot ulcer using larval therapyA Knowles
Manchester Diabetes Centre, Manchester
Nurs Stand 16:73-6. 2001b>Diabetic foot ulcers should be treated to maintain health status, improve quality of life, reduce the number of amputations and lower costs...
- Treatment of diabetic foot infection with hyperbaric oxygen therapyChin En Chen
Department of Orthopedic Surgery, Golden Hospital, 12 2, Minsheng E Rd, Pingtung City 900, Taiwan, ROC
Foot Ankle Surg 16:91-5. 2010This study was performed to evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) in the treatment of the infected diabetic foot.
- The diabetic foot: perspectives from Chennai, South IndiaVijay Viswanathan
M V Hospital for Diabetes and Diabetes Research Centre, Royapuram, Chennai, India
Int J Low Extrem Wounds 6:34-6. 2007..Prompt and aggressive treatment of diabetic foot ulcers can often prevent exacerbation of the problem and eliminate the potential for amputation...
- Epidemiology of diabetic foot problems and predictive factors for limb lossAziz Nather
Department of Orthopaedic Surgery, National University Hospital, Singapore
J Diabetes Complications 22:77-82. 2008The aim of this study was to evaluate the epidemiology of diabetic foot problems (DFP) and predictive factors for major amputations (below- and above-knee).
- Integration of plantar soft tissue stiffness measurements in routine MRI of the diabetic footA Gefen
Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, 69978, Tel Aviv, Israel
Clin Biomech (Bristol, Avon) 16:921-5. 2001..A method of measuring mechanical properties of plantar soft tissues in vivo by integrating a photoelastic technique into an MRI system is presented...
- Prevalence of risk factors for diabetic foot complicationsFatma Al-Maskari
Department of Community Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, PO Box 17666, UAE
BMC Fam Pract 8:59. 2007..The aim of this study was to determine the prevalence and risk factors for foot complications among diabetic patients in Al-Ain district, United Arab Emirates (UAE)...
- Multi-plug insole design to reduce peak plantar pressure on the diabetic foot during walkingRicardo L Actis
Engineering Software Research and Development, Inc, 111 West Port Plaza, Suite 825, St Louis, MO 63146, USA
Med Biol Eng Comput 46:363-71. 2008....
- The treatment of diabetic foot infections: focus on ertapenemMichael Edmonds
Diabetic Foot Clinic, King s College Hospital, Denmark Hill, London, UK
Vasc Health Risk Manag 5:949-63. 2009Clinically, 3 distinct stages of diabetic foot infection may be recognized: localized infection, spreading infection and severe infection. Each of these presentations may be complicated by osteomyelitis...
- Negative-pressure wound therapy and diabetic foot amputations: a retrospective study of payer claims dataRobert G Frykberg
Podiatry Section, Carl T Hayden Veterans Administration Medical Center, Phoenix, AZ 85012, USA
J Am Podiatr Med Assoc 97:351-9. 2007This study was undertaken to assess the benefits of negative-pressure wound therapy (NPWT) versus traditional wound therapies in reducing the incidence of lower-extremity amputations in patients with diabetic foot ulcers.
- What is the role of hyperbaric oxygen in the management of diabetic foot disease?Magnus Löndahl
Institution of Clinical Sciences in Lund, Lund University, Lund, Sweden
Curr Diab Rep 11:285-93. 2011..A typical HBO treatment protocol of diabetic foot ulcer involves 20 to 40 sessions...
- [Diabetic foot and risk factors]V Martín Borge
Unidad de Diabetes, Hospital Universitario La Paz, Madrid
An Med Interna 24:263-6. 2007To identify clinic and metabolic risk factors for diabetic neuropathy and peripheral arterial disease in patients evaluated in a diabetic foot unit care.
- Impact of diabetic foot related complications on the Health Related Quality of Life (HRQol) of patients--a regional study in SpainE García-Morales
Complutense University of Madrid, Madrid, Spain
Int J Low Extrem Wounds 10:6-11. 2011The diabetic foot reduces the health-related quality of life (HRQoL) in patients with diabetes mellitus. This study aims at ascertaining the impact of the etiological factors of the diabetic foot on the various aspects of HRQoL...
- Predictive model of short-term amputation during hospitalization of patients due to acute diabetic foot infectionsJosé Barberán
Infectious Diseases Department, Hospital Central de la Defensa Gomez Ulla, Madrid, Spain
Enferm Infecc Microbiol Clin 28:680-4. 2010Factors predicting short-term amputation during hospital treatment of patients admitted for acute diabetic foot infections are of interest for clinicians managing the acute episode.
- Diabetic foot ulcers and infections: current conceptsJason H Calhoun
Department of Orthopaedics and Rehabilitation, University of Texas Medical Branch, Galveston, USA
Adv Skin Wound Care 15:31-42; quiz 44-5. 2002
- [Outcome of minor amputations at the diabetic foot in relation to bone histopathology: a clinical audit]A Hachmöller
Klinik fur Endokrinologie, Diabetologie und Rheumatologie, Heinrich Heine Universitat Dusseldorf
Zentralbl Chir 132:491-6. 2007to assess the clinical course of minor amputations at the diabetic foot in relation to bone histopathology at the affected site, and at the osteotomy site.
- Treatment of long-standing, poor-healing diabetic foot ulcers with topical negative pressure in the Torres StraitDale Tan
Thursday Island Hospital, Thursday Island, Queensland, Australia
Aust J Rural Health 15:275-6. 2007
- Resource utilization and economic costs of care based on a randomized trial of vacuum-assisted closure therapy in the treatment of diabetic foot woundsJan Apelqvist
Department of Endocrinology, University Hospital of Malmo, Malmo, Sweden
Am J Surg 195:782-8. 2008..To evaluate resource utilization and direct economic costs of care for patients treated with negative-pressure wound therapy (NPWT), using the Vacuum-Assisted Closure (V.A.C.) system, compared to standard moist wound therapy (MWT)...
- Wound bioburden and infection-related complications in diabetic foot ulcersSue E Gardner
University of Iowa College of Nursing, Iowa City, IA 52242, USA
Biol Res Nurs 10:44-53. 2008The identification and diagnosis of diabetic foot ulcer (DFU) infections remains a complex problem...
- Intralesional injections of Citoprot-P (recombinant human epidermal growth factor) in advanced diabetic foot ulcers with risk of amputationJosé I Fernández Montequín
Service of Diabetic Microangiopathy, National Institute for Angiology and Vascular Surgery, Havana, Cuba
Int Wound J 4:333-43. 2007To investigate the efficacy and safety of recombinant human epidermal growth factor (rhEGF) in advanced diabetic foot ulcers (DFU) A double-blind trial was carried out to test two rhEGF dose levels in type 1 or 2 diabetes patients with ..
- Wound bed preparation with 10-percent phenytoin ointment increases the take of split-thickness skin graft in large diabetic ulcersNidal Younes
Department of Surgery and Faculty of Medicine, University of Jordan
Dermatol Online J 12:5. 2006Healing of large diabetic foot ulcers may be difficult, particularly if the blood supply and chronic infection do not allow primary suturing. Split-thickness skin graft is a simple reconstructive technique used to close large wounds...
- Effectiveness of recombinant human platelet-derived growth factor for the treatment of diabetic neuropathic foot ulcersDavid J Margolis
Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Wound Repair Regen 13:531-6. 2005....
- An evaluation of three wound measurement techniques in diabetic foot woundsJulia Shaw
Regional Centre for Endocrinology and Diabetes, Royal Hospitals, Belfast, Northern Ireland
Diabetes Care 30:2641-2. 2007
- Diabetic foot infections in the elderly: primary amputation versus 'foot-sparing surgery'. A case reportLuis R Leon
Vascular Surgery Section, Southern Arizona Veteran Affairs Health Care System SAVAHCS, Tucson, AZ 85723, USA
Int Wound J 4:315-21. 2007..Our case unfortunately mirrors a common method of evaluation and therapy of patients with such comorbidities and sets up the stage for a very controversial subject...
- The incidence and risks of failure to heal after lower extremity amputation for the treatment of diabetic neuropathic foot ulcerD Scot Malay
Ankle and Foot Medical Center of the Delaware Valley, Philadephia, PA 19104, USA
J Foot Ankle Surg 45:366-74. 2006..These findings should be useful to clinicians treating diabetic neuropathic foot ulcers, and should aid surgeons in the determination of the most appropriate level for lower extremity amputation...
- Best practice in the assessment and management of diabetic foot ulcersLillian Delmas
Ottawa Hospital Rehabilitation Centre, ON
Rehabil Nurs 31:228-34. 2006..This information better equips rehabilitation nurses to promote ulcer prevention strategies; identifies key factors in ulcer risk; and utilizes current, best evidence for ulcer assessment, management, and evaluation...
- Predictors, consequences and costs of diabetes-related lower extremity amputation complicating type 2 diabetes: the Fremantle Diabetes StudyW A Davis
School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, WA 6959, Australia
Diabetologia 49:2634-41. 2006..The aims of this study were to assess the incidence, predictors, consequences, and inpatient cost of lower extremity amputation (LEA) in a community-based cohort of type 2 diabetic patients...
- The use of medical hyperspectral technology to evaluate microcirculatory changes in diabetic foot ulcers and to predict clinical outcomesLalita Khaodhiar
Joslin Beth Israel Deaconess Foot Center and Microcirculation Laboratory, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
Diabetes Care 30:903-10. 2007..We tested the ability of medical hyperspectral technology (HT), a novel diagnostic scanning technique that can quantify tissue oxy- and deoxyhemoglobin to predict diabetic foot ulcer healing.
- Long-term outcome and disability of diabetic patients hospitalized for diabetic foot ulcers: a 6.5-year follow-up studyEdouard Ghanassia
Le Centre Hospitalier Universitaire Montpellier, Montpellier, France
Diabetes Care 31:1288-92. 2008The long-term outcome and functional status of subjects hospitalized for diabetic foot ulcers have been poorly studied and thus are the topics of this study.
- Do US veterans wear appropriately sized shoes?: the Veterans Affairs shoe size selection studyBrent P Nixon
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
J Am Podiatr Med Assoc 96:290-2. 2006Poorly fitting footwear has frequently been cited as an etiologic factor in the pathway to diabetic foot ulceration...
- A new wound-based severity score for diabetic foot ulcers: A prospective analysis of 1,000 patientsStefan Beckert
Department of General and Transplant Surgery, , , Germany
Diabetes Care 29:988-92. 2006OBJECTIVE: Several well-accepted classification systems are available for diabetic foot ulcers. However, there are only a few and scientifically not validated severity scores...
- [Granulation tissue induced by vacuum-therapy on the exposed chondral part of the condyle of femur after disarticulation of the knee]T Othman
Deutsches Diabetes Zentrum,
Zentralbl Chir 131:S151-2. 2006
- Orthotic management of the neuropathic limbNancy Williams Elftman
Phys Med Rehabil Clin N Am 17:115-57. 2006..The combined team expertise with state-of-the-art techniques have enabled wound healing, limb salvage, and improved quality of life for this high-risk population...
- Scottish foot ulcer risk score predicts foot ulcer healing in a regional specialist foot clinicGraham Leese
Ward 1 and 2 Ninewells Hospital, Dundee, U K DD1 9SY
Diabetes Care 30:2064-9. 2007....
- Bone histomorphology may be unremarkable in diabetes mellitusErnst Chantelau
Department of Endocrinology, Diabetes and Rheumatology, Heinrich Heine University of Dusseldorf, Germany
Med Klin (Munich) 102:429-33. 2007..Histomorphological studies on bone in human diabetes mellitus are scarce. The aim of this study was to observe the histomorphological appearance of bone in amputation specimens from feet of patients with diabetes mellitus...
- Mortality and morbidity after transmetatarsal amputation: retrospective review of 101 casesJason Pollard
Dept. of Orthopedics and Podiatric Surgery, Kaiser Permanente Medical Center, 280 W. MacArthur Boulevard, Oakland, CA 94611, USA
J Foot Ankle Surg 45:91-7. 2006..4%). Postsurgical complications developed in 88 cases (87.1%). Two patients died within 30 days postoperatively. These data suggest that TMA is associated with high complication rates in a diabetic and vasculopathic population...
- Caring for the diabetic patient with a foot ulcerSylvie Hampton
Tissue Viability Consultant, Eastbourne
Br J Nurs 15:S22-7. 2006Neuropathy is the most common complication of diabetes. Those patients with diabetic foot ulceration on the plantar, medial and lateral surfaces of the foot will almost all have clinically significant peripheral neuropathy...
- Use of the SINBAD classification system and score in comparing outcome of foot ulcer management on three continentsPaul Ince
Foot Ulcer Trials Unit, Diabetes and Endocrinology, City Hospital, Nottingham, UK
Diabetes Care 31:964-7. 2008To compare populations with and outcomes of diabetic foot ulcers managed in the U.K., Germany, Tanzania, and Pakistan and to explore the use of a new score of ulcer type in comparing outcomes among different countries.
- Midfoot amputations expand limb salvage rates for diabetic foot infectionsPatrick A Stone
Division of Vascular and Endovascular Surgery, University of South Florida, Tampa, FL 33606, USA
Ann Vasc Surg 19:805-11. 2005..Transtarsal amputations salvaged over half of nonhealing TMAs with excellent functional results...
- Peripheral neuropathy in the hands of diabetic patients with lower extremity amputationsM S Pinzur
Loyola University Medical School, Maywood, Illinois, USA
Am J Orthop 30:121-4. 2001....
- Maximizing length and optimizing biomechanics in foot amputations by avoiding cookbook recipes for amputationChristopher Attinger
Semin Vasc Surg 16:44-66. 2003
- [Interdisciplinary treatment of diabetic foot syndrome]A Eckardt
Orthopädische Klinik und Poliklinik, Johannes Gutenberg Universitat Mainz
Orthopade 32:190-8. 2003The amputation rate in patients with diabetic foot syndrome (DFS) in Germany is still as high as 28,000 per year. Ischemia and osteomyelitis often complicate the DFS...
- [The MRSA patient in technical orthopaedics and rehabilitation]C Hornberg
Fakultät für Gesundheitswissenschaften, Universitat, Bielefeld
Orthopade 32:213-7. 2003..All patients had chronic wound healing disorders of the lower extremities which were due to peripheral neuropathies, diabetes mellitus and/or obstructive disease of the arteries. All patients were at risk for colonisation with MRSA...
- [Link-Witzel operation for diabetics]A Koller
Klinik und Poliklinik für Technische Orthopädie und Rehabilitation, Westfalische Wilhelms Universitat, Munster
Orthopade 32:231-5. 2003..The surgical procedure according to Link and Witzel should thus not only be considered as an alternative to Chopart's amputation, but also as a further method to spare diabetics major amputations...
- Classifying diabetic foot surgery: toward a rational definitionD G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ 85723, USA
Diabet Med 20:329-31. 2003The purpose of this manuscript was to describe a classification of diabetic foot surgery performed in the absence of critical limb ischaemia...
- The diabetic footPeter J Watkins
King's Diabetes Centre, King's College Hospital, London
BMJ 326:977-9. 2003
- The fitting of amputated and nonamputated diabetic feet. A French experience at the Villiers-Saint-Denis HospitalJean-Claude Dupre
La Renaissance Sanitaire, , Saint-Denis, France
J Am Podiatr Med Assoc 93:221-8. 2003..This article describes a complete range of orthoses and prostheses, adapted to each patient, that allow recovery of the standing position, gait ability, and physical activity...
- Evaluation of the impact of chiropodist care in the secondary prevention of foot ulcerations in diabetic subjectsJohannes Plank
Division of Diabetes und Metabolism, Department of Internal Medicine, Karl Franzens University Hospital, Graz, Austria
Diabetes Care 26:1691-5. 2003To evaluate the influence of regular chiropodist care on the recurrence rate of diabetic foot ulcers within 1 year.
- Wound healing for foot ulcersJeffrey A Stone
Diabetes Self Manag 20:38, 40, 42 passim. 2003
- [Incidence of factors favoring recurrent foot ulcers in diabetic patients]A Diouri
, Casablanca, Maroc
Ann Endocrinol (Paris) 63:491-6. 2002..our findings illustrate the importance of specialized management of diabetic patients with foot lesions. Adequate care of the lesions and preventive measures against risk factors are needed...
- Wound EMR to Decrease Limb Amputations in Persons with DiabetesHarold Brem; Fiscal Year: 2010..Wound Electronic Medical Record (OWEMR) as a clinical intervention tool reduces amputations resulting from diabetic foot ulcers (DFUs) in a variety of healthcare settings...
- FDG-PET Imaging in Complicated Diabetic FootAbass Alavi; Fiscal Year: 2005..determine the efficacy of FDG-PET imaging in the diagnosis of osteomyelitis or deep infection in patients with diabetic foot in a large patient population...
- Growth factor delivery patch for wound healingFen Zhang; Fiscal Year: 2005..5 million Americans annually, particularly the elderly. Diseases within this family include diabetic foot ulcers, venous stasis ulcers, and pressure ulcers...
- Evaluation of a novel connexin-based peptide for the treatment of diabetic woundsGautam Ghatnekar; Fiscal Year: 2007..Approximately 20 percent of patients with diabetes will develop foot ulceration in their lifetime. Diabetic foot ulceration (DFU) represents a major problem that can significantly impair the patient's quality of life, ..
- Role of Neuropeptides in Diabetic Foot ProblemsARISTIDIS contact VEVES; Fiscal Year: 2010Impaired wound healing is an important clinical problem in diabetes resulting in failure to completely heal diabetic foot ulcers and more that 75,000 lower extremity amputations annually...
- Diabetic Foot and Pressure Ulcer DatabankHarold Brem; Fiscal Year: 2007..decrease the morbidity and mortality in more than 3 million patients suffering from pressure ulcers and diabetic foot ulcers...
- Diabetic Foot and Pressure Ulcer DatabankHarold Brem; Fiscal Year: 2009..decrease the morbidity and mortality in more than 3 million patients suffering from pressure ulcers and diabetic foot ulcers...
- Emotional Stress and Wound Healing in DiabetesAndrew Boulton; Fiscal Year: 2007b>Diabetic foot ulcers are common and may lead to amputation: efforts to improve foot ulcer healing would have an impact on the frequency of lower limb amputation in the USA...
- The Development and Testing of a Sonic Treatment Brush for Diabetic Foot UlcersROBERT AKRIDGE; Fiscal Year: 2007Non-healing diabetic foot ulcers are potentially a limb- and life-threatening complication of chronic diabetes mellitus and associated peripheral neuropathy...
- Emotional Stress and Wound Healing in DiabetesLoretta Vileikyte; Fiscal Year: 2009b>Diabetic foot ulcers are common and may lead to amputation: efforts to improve foot ulcer healing would have an impact on the frequency of lower limb amputation in the USA...
- Emotional Stress and Wound Healing in DiabetesLoretta Vileikyte; Fiscal Year: 2010b>Diabetic foot ulcers are common and may lead to amputation: efforts to improve foot ulcer healing would have an impact on the frequency of lower limb amputation in the USA...
- Clinical Testing of Hyperspectral Assessment & Prediction of Diabetic Foot UlcersKEVIN SCHOMACKER; Fiscal Year: 2007..We believe FHSI can have positive impact on quality of life of people with diabetes, impacting morbidity & mortality & lowering overall healthcare costs. ..
- Topical Salicylanilides to Treat Diabetic Foot UlcerJoseph Dunn; Fiscal Year: 2002..class of patented, Lipophilic, Antimicrobial, Anti-inflammatory Drugs (LAADs) for the treatment of Diabetic Foot Ulcer (DFU)...
- Skin Interface Friction TransducerJEFFREY SCHOESS; Fiscal Year: 2003..is 15 to 46 times higher in diabetics than persons without diabetic mellitus, with the vast majority of diabetic foot complications resulting in amputation due to formation of skin ulcers...
- Diabetic Foot Ulcer Healing by Load Relieving DressingsJoseph Loomis; Fiscal Year: 2006..abstract_text> ..
- INTERACTION OF ENTEROCOCCUS FAECALIS WITH MACROPHAGESClaudia Gentry Weeks; Fiscal Year: 2003..blood, endocardium, genitourinary tract, abdomen, wounds, and skin and soft tissue (burns, decubitis ulcers, diabetic foot ulcers). Preliminary studies in this laboratory have demonstrated that at least two E...
- Discovery of a Platelet Derived Growth Factor Peptide-based MimeticPaul Hamilton; Fiscal Year: 2006Project Summary/Abstract: Diabetic foot ulcers are a significant health problem that imposes high costs on both patients and society (Boulton, Vileikyte et al. 2005)...
- INTRACELLULAR ENERGY DELIVERY AND DIABETIC WOUNDSSufan Chien; Fiscal Year: 2007..5 to 4.5 million will develop a chronic wound in their lifetime. The overall cost of diabetic foot problems, including loss of productivity, could be as high as $20 billion per year...
- INTRACELLULAR ENERGY DELIVERY AND DIABETIC WOUNDSSufan Chien; Fiscal Year: 2009..5 to 4.5 million will develop a chronic wound in their lifetime. The overall cost of diabetic foot problems, including loss of productivity, could be as high as $20 billion per year...
- INTRACELLULAR ENERGY DELIVERY AND DIABETIC WOUNDSSufan Chien; Fiscal Year: 2010..5 to 4.5 million will develop a chronic wound in their lifetime. The overall cost of diabetic foot problems, including loss of productivity, could be as high as $20 billion per year...
- INTRACELLULAR ENERGY DELIVERY AND DIABETIC WOUNDSSufan Chien; Fiscal Year: 2010
- BIOPHYSICAL DETERMINANTS OF DIABETIC FOOT ULCER HEALINGCharles Saltzman; Fiscal Year: 2003..project grant (R01) is to develop a comprehensive understanding of the biophysical factors determining diabetic foot ulcer healing. Approximately 16 million Americans are known to have diabetes...
- Local Angiogenic Gene Therapy/VEGF/Treat Diabetic UlcersHarold Brem; Fiscal Year: 2003..The estimated annual cost of $9 billion doesn't include the pam, suffering, and morbidity of diabetic foot ulcers...
- Impaired Wound Healing in Diabetic Foot UlcerationAristidis Veves; Fiscal Year: 2007b>Diabetic foot ulceration (DFU) is a major problem that significantly impairs the quality of life of the patient, leads to prolonged hospitalization and may require a major amputation...
- TOPICAL RETINOIDS FOR DIABETIC FOOT ULCERSJames Varani; Fiscal Year: 2003..In the majority of diabetic subjects, the underlying factor which contributes to eventual amputation is the diabetic foot ulcer...
- Healing Chronic Wounds by Controlling Microbial BiofilmPhilip Stewart; Fiscal Year: 2007..Wounds that fail to heal, such as diabetic foot ulcers, venous leg ulcers, and pressure ulcers are a major source of morbidity, mortality, and health care ..
- PROMOTION OF WOUND VASCULARIZATION AND CLOSURERonald Hill; Fiscal Year: 2005Progression of diabetic foot ulcers is the leading cause of lower limb amputations in the U.S. More than 800,000 foot ulcers are treated annually with progression to more than 86,000 amputations each year. Between 1/4 to 1/2 of the $ 27...
- PHARMACOLOGIC PROMOTION OF WOUND HEALINGBruce Cronstein; Fiscal Year: 2007..These studies should provide new insights into the mechanism by which adenosine A2A receptor agonists, a novel therapy undergoing clinical trials for wound healing of diabetic foot ulcers, promote wound healing.
- Healing Chronic Wounds by Controlling Microbial BiofilmPhilip Stewart; Fiscal Year: 2007..Wounds that fail to heal, such as diabetic foot ulcers, venous leg ulcers, and pressure ulcers are a major source of morbidity, mortality, and health care ..