intracranial hemorrhages

Summary

Summary: Bleeding within the intracranial cavity, including hemorrhages in the brain and within the cranial epidural, subdural, and subarachnoid spaces.

Top Publications

  1. ncbi Image and diagnosis. Intracranial haemorrhage due to vitamin K deficiency, as the first symptom of extrahepatic biliary atresia
    V Ertekin
    Faculty of Medicine, Department of Pediatric Gastroenterology, Ataturk University, Erzurum, Turkey
    West Indian Med J 54:392, 397. 2005
  2. pmc Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke
    Alex K Harris
    Program in Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, Georgia, USA
    BMC Neurosci 6:49. 2005
  3. doi Hemorrhagic manifestations of reversible cerebral vasoconstriction syndrome: frequency, features, and risk factors
    Anne Ducros
    Emergency Headache Center Head and Neck Clinic, Lariboisiere Hospital, Paris, France
    Stroke 41:2505-11. 2010
  4. ncbi Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke
    Joan Montaner
    Cerebrovascular Unit, Vall d Hebron Hospital, Barcelona, Spain
    Circulation 107:598-603. 2003
  5. pmc Intracranial bleeding in patients with traumatic brain injury: a prognostic study
    Pablo Perel
    Epidemiology and Population Health Department, London School of Hygiene and Tropical Medicine, London, UK
    BMC Emerg Med 9:15. 2009
  6. ncbi Clinical and neuroradiological predictors of mortality in patients with primary pontine hemorrhage
    Kemal Balci
    Department of Neurology, School of Medicine, Trakya University, Edirne, Turkey
    Clin Neurol Neurosurg 108:36-9. 2005
  7. ncbi Risk score model for fatal intracranial hemorrhage in acute leukemia
    H Kim
    Division of Hematology Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
    Leukemia 20:770-6. 2006
  8. ncbi Intracranial hemorrhage in late hemorrhagic disease of the newborn
    Puneet A Pooni
    Department of Pediatrics, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
    Indian Pediatr 40:243-8. 2003
  9. doi Statin use and functional outcome after tissue plasminogen activator treatment in acute ischaemic stroke
    I Miedema
    Department of Neurology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Cerebrovasc Dis 29:263-7. 2010
  10. ncbi Prediction model for mortality after intracranial hemorrhage in patients with leukemia
    Farshid Dayyani
    Division of Cancer Medicine, University of Texas, MD Anderson Cancer Center, Houston, USA
    Am J Hematol 86:546-9. 2011

Research Grants

Detail Information

Publications214 found, 100 shown here

  1. ncbi Image and diagnosis. Intracranial haemorrhage due to vitamin K deficiency, as the first symptom of extrahepatic biliary atresia
    V Ertekin
    Faculty of Medicine, Department of Pediatric Gastroenterology, Ataturk University, Erzurum, Turkey
    West Indian Med J 54:392, 397. 2005
  2. pmc Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke
    Alex K Harris
    Program in Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, Georgia, USA
    BMC Neurosci 6:49. 2005
    ..While gelatinase (MMP-2 and -9) activity is increased after focal ischemia/reperfusion injury in the brain, the relative contribution of neutrophils to the MMP activity and to the development of hemorrhagic transformation remains unknown...
  3. doi Hemorrhagic manifestations of reversible cerebral vasoconstriction syndrome: frequency, features, and risk factors
    Anne Ducros
    Emergency Headache Center Head and Neck Clinic, Lariboisiere Hospital, Paris, France
    Stroke 41:2505-11. 2010
    ..The aim of this study was to describe the frequency, patterns, and risk factors of intracranial hemorrhages in RCVS.
  4. ncbi Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke
    Joan Montaner
    Cerebrovascular Unit, Vall d Hebron Hospital, Barcelona, Spain
    Circulation 107:598-603. 2003
    ..We aimed to correlate plasmatic MMP levels with the appearance of intracranial bleeding complications in stroke patients treated with t-PA...
  5. pmc Intracranial bleeding in patients with traumatic brain injury: a prognostic study
    Pablo Perel
    Epidemiology and Population Health Department, London School of Hygiene and Tropical Medicine, London, UK
    BMC Emerg Med 9:15. 2009
    ..We analysed data from the Trauma Audit & Research Network (TARN), a large European trauma registry, to evaluate the association between the size of IB and mortality in patients with TBI...
  6. ncbi Clinical and neuroradiological predictors of mortality in patients with primary pontine hemorrhage
    Kemal Balci
    Department of Neurology, School of Medicine, Trakya University, Edirne, Turkey
    Clin Neurol Neurosurg 108:36-9. 2005
    Primary pontine hemorrhage (PPH) accounts approximately for about 5-10% of intracranial hemorrhages, and PPHs are known to have a much less uniform prognosis...
  7. ncbi Risk score model for fatal intracranial hemorrhage in acute leukemia
    H Kim
    Division of Hematology Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
    Leukemia 20:770-6. 2006
    ..001). Overall survival was significantly shorter in the HRG compared with the LRG. The RS model we constructed to predict the occurrence of FICH will be verified through prospective studies...
  8. ncbi Intracranial hemorrhage in late hemorrhagic disease of the newborn
    Puneet A Pooni
    Department of Pediatrics, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
    Indian Pediatr 40:243-8. 2003
    ..Three patients expired. Late HDN is still an important cause of mortality and morbidity in developing countries where vitamin K prophylaxis is not routinely practiced. Isolated intracranial hemorrhage is a common mode of presentation...
  9. doi Statin use and functional outcome after tissue plasminogen activator treatment in acute ischaemic stroke
    I Miedema
    Department of Neurology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Cerebrovasc Dis 29:263-7. 2010
    ..This study investigated whether patients on prior statin therapy and treated with tissue plasminogen activator (tPA) for acute ischaemic stroke have a better functional outcome than statin-naïve patients...
  10. ncbi Prediction model for mortality after intracranial hemorrhage in patients with leukemia
    Farshid Dayyani
    Division of Cancer Medicine, University of Texas, MD Anderson Cancer Center, Houston, USA
    Am J Hematol 86:546-9. 2011
    ....
  11. ncbi Experience of recombinant activated factor VII (NovoSeven) in the operating theatre and intensive care unit for the management of intracranial bleeding in nonhaemophilic patients
    Michael Felfernig
    Department of Anaesthesia and General Intensive Care, Medical University Vienna, Waehringerguertel 18 20, 1090 Vienna, Austria
    Clin Neurol Neurosurg 110:227-32. 2008
    ..Our aim was to explore the use of recombinant activated factor VII (rFVIIa NovoSeven Novo Nordisk, A/S, Bagsvaerd, Denmark) for the management of ICH in the operating theater and intensive care unit...
  12. ncbi Neurodevelopmental outcome in children with posthemorrhagic hydrocephalus
    Yasuyuki Futagi
    Division of Pediatric Neurology, Osaka Medical Center and Research Institute for Maternal and Child Health, 840 Murodo cho, Izumi, Osaka 594 1101, Japan
    Pediatr Neurol 33:26-32. 2005
    ....
  13. doi Recombinant factor VIIa for warfarin-associated intracranial bleeding
    Can Ilyas
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Clin Anesth 20:276-9. 2008
    ..To examine the efficacy of recombinant factor VIIa (rVIIa) in reversing warfarin-induced coagulopathy in trauma patients presenting with intracranial hemorrhage (ICH)...
  14. doi Prediction of fatal intracranial hemorrhage in patients with acute myeloid leukemia
    C Y Chen
    Department of Internal Medicine, Division of Hematology, National Taiwan University Hospital, Taipei, Taiwan
    Ann Oncol 20:1100-4. 2009
    ..Intracranial hemorrhage (ICH) is the second leading cause of mortality in patients with acute myeloid leukemia (AML). However, the prognostic factors for ICH in AML patients are still under investigation...
  15. ncbi Intracranial hemorrhage due to late hemorrhagic disease in two siblings
    Huseyin Per
    Department of Pediatric Neurology, Erciyes University Medical Faculty, Kayseri, Turkey
    J Emerg Med 31:49-52. 2006
    ..In this study, we report on two siblings with intracranial bleeding who were fully breastfed without a routine supplementation of vitamin K. Vitamin K should be given to all newborns as a single, intramuscular dose of 1 mg...
  16. ncbi Diagnosis of acute lymphoblastic leukemia from intracerebral hemorrhage and blast crisis. A case report and review of the literature
    Matthew R Naunheim
    Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Clin Neurol Neurosurg 112:575-7. 2010
    ..This case demonstrates that the presence of hyperleukocytosis in a patient with intracerebral hemorrhage should raise clinical suspicion for acute leukemia as the cause of the ICH...
  17. doi Warfarin and intracranial haemorrhage
    Rebecca Appelboam
    Anaesthesia and Intensive Care Medicine, Royal Devon and Exeter Hospital, Barrack Road, Exeter, Devon, UK
    Blood Rev 23:1-9. 2009
    ..The specific management of patients with prosthetic heart valves is also discussed. A summary of current societal guidelines is also included, as are some key practice points...
  18. pmc Lasting effects of preterm birth and neonatal brain hemorrhage at 12 years of age
    Thuy Mai Luu
    Women and Infants Hospital, Department of Pediatrics, 101 Dudley St, Providence, RI 02905, USA
    Pediatrics 123:1037-44. 2009
    ....
  19. ncbi Angiogenic inhibition reduces germinal matrix hemorrhage
    Praveen Ballabh
    Department of Pediatrics, New York Medical College Westchester Medical Center, Valhalla, New York 10595, USA
    Nat Med 13:477-85. 2007
    ..Thus, by suppressing germinal matrix angiogenesis, prenatal celecoxib or ZD6474 treatment may be able to reduce both the incidence and severity of GMH in susceptible premature infants...
  20. pmc Intracranial haemorrhage due to late onset vitamin K deficiency bleeding in Hanoi province, Vietnam
    N Danielsson
    Astrid Lindgren s Children s Hospital, Stockholm, Sweden
    Arch Dis Child Fetal Neonatal Ed 89:F546-50. 2004
    ..In many developing countries vitamin K prophylaxis is not routinely administered at birth. There are insufficient data to assess the cost effectiveness of its implementation in such countries...
  21. ncbi Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study
    Nils Wahlgren
    Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Lancet 369:275-82. 2007
    ..Under European Union regulations, SITS-MOST was required to assess the safety profile of alteplase in clinical practice by comparison with results in randomised controlled trials...
  22. ncbi The prognostic impact of clinical and CT parameters in patients with pontine hemorrhage
    Rainer Dziewas
    Department of Neurology, University of Munster, Munster, Germany
    Cerebrovasc Dis 16:224-9. 2003
    ..In patients with pontine hemorrhage (PH), an accurate prognostic assessment is critical for establishing a reasonable therapeutic approach...
  23. ncbi Intracranial hemorrhages due to late-type vitamin K deficiency bleeding
    Melih Cekinmez
    Department of Neurosurgery, Faculty of Medicine, Baskent University, Dadaloglu Mahallesi, 01250, Yuregir, Adana, Turkey
    Childs Nerv Syst 24:821-5. 2008
    ..Late-type VKDB has particular importance due to frequent intracranial hemorrhages that lead to high mortality and morbidity...
  24. doi Plasma VAP-1/SSAO activity predicts intracranial hemorrhages and adverse neurological outcome after tissue plasminogen activator treatment in stroke
    Mar Hernandez-Guillamon
    Neurovascular Research Laboratory, Institut de Recerca, Hospital Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain
    Stroke 41:1528-35. 2010
    ..We aimed to study plasma VAP-1/SSAO activity in relation to the risk for intracranial bleeding complications in patients with stroke treated with tissue plasminogen activator (tPA), the greatest safety concern with this treatment...
  25. pmc Migraine and risk of haemorrhagic stroke in women: prospective cohort study
    Tobias Kurth
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMJ 341:c3659. 2010
    ..To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke...
  26. ncbi S100B protein in biological fluids: a tool for perinatal medicine
    Fabrizio Michetti
    Institute of Anatomy, Catholic University, Largo Francesco Vito 1, I 00168 Rome, Italy
    Clin Chem 48:2097-104. 2002
    ..Finally, because of the neurotrophic role putatively played by S100B, its measurement in biological fluids at pre-/perinatal ages makes it a candidate for the laboratory evaluation of brain maturation...
  27. ncbi Intracranial hemorrhage and vitamin K deficiency associated with biliary atresia: summary of 15 cases and review of the literature
    Hideyuki Akiyama
    Department of Neurosurgery, Kobe Children s Hospital, Kobe, Japan
    Pediatr Neurosurg 42:362-7. 2006
    ..Moreover, early performance of Kasai portoenterostomy is possible even for patients who have undergone craniotomy...
  28. doi Reliability of diagnosis of traumatic brain injury by computed tomography in the acute phase
    Jussi P Laalo
    Medical Imaging Centre, Turku University Central Hospital, Turku, Finland
    J Neurotrauma 26:2169-78. 2009
    ..Experience increased accuracy, yet even between the reports of the most experienced readers, there were marked differences...
  29. pmc Use of recombinant factor VIIa in patients with warfarin-associated intracranial hemorrhage
    David L Brody
    Neurology Neurosurgery Intensive Care Unit, Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neurocrit Care 2:263-7. 2005
    ..Current therapies are associated with significant complications and/or prolonged time to correction of coagulopathy. Recombinant factor VIIa (FVIIa) might allow faster and safer correction of coagulopathy...
  30. ncbi Cause is the main predictor of outcome in patients with pontine hemorrhage
    Alejandro A Rabinstein
    Neurological Neurosurgical Intensive Care Unit, Saint Mary s Hospital, Rochester, Minn, USA
    Cerebrovasc Dis 17:66-71. 2004
    ..Pontine hemorrhages frequently lead to death or severe disability. Predictors of early mortality have been previously described but little is known about the factors influencing long-term disability...
  31. ncbi Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation
    Guy Rosenthal
    Department of Neurosurgery, University of California, San Francisco, CA 94117, USA
    J Neurosurg 108:575-87. 2008
    ..We studied the effects of hemoglobin-based oxygen-carrying (HBOC)-201 solution compared with lactated Ringer (LR) solution in a large animal model of brain injury and hemorrhage, in a blinded prospective randomized study...
  32. ncbi Plasma cellular-fibronectin concentration predicts hemorrhagic transformation after thrombolytic therapy in acute ischemic stroke
    Mar Castellanos
    Department of Neurology, Hospital Universitari Doctor Josep Trueta in affiliation with the UAB, Avda Francia s n, Girona 17007, Spain
    Stroke 35:1671-6. 2004
    ..We investigated whether high plasma levels of c-Fn were associated with hemorrhagic transformation (HT) after treatment with tissue plasminogen activator (tPA) in patients with acute stroke...
  33. ncbi Different risk factors for different stroke subtypes: association of blood pressure, cholesterol, and antioxidants
    J M Leppälä
    Department of Public Health, University of Helsinki, Finland
    Stroke 30:2535-40. 1999
    ..Blood pressure is an important risk factor for stroke, but the roles of serum total and HDL cholesterol, alpha-tocopherol, and beta-carotene are poorly established. We studied these factors in relation to stroke subtypes...
  34. pmc Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition
    Govindaiah Vinukonda
    Department of Paediatrics, New York Medical College Westchester Medical Centre, Valhalla, NY 10595, USA
    Brain 133:2264-80. 2010
    ....
  35. doi IV thrombolysis and statins
    S T Engelter
    Department of Neurology, University Hospital Basel, Basel, Switzerland
    Neurology 77:888-95. 2011
    ..To examine whether prior statin use affects outcome and intracranial hemorrhage (ICH) rates in stroke patients receiving IV thrombolysis (IVT)...
  36. ncbi Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants
    B Schmidt
    Department of Pediatrics, McMaster University, Hamilton, Ont, Canada
    N Engl J Med 344:1966-72. 2001
    ..Whether prophylaxis with indomethacin confers any long-term benefits that outweigh the risks of drug-induced reductions in renal, intestinal, and cerebral blood flow is not known...
  37. ncbi Indomethacin prophylaxis for intraventricular hemorrhage in very low birth weight babies
    P Arun Kumar Nair
    Neonatal Intensive Care Unit, Royal Hospital, Muscat, Sultanate of Oman
    Indian Pediatr 41:551-8. 2004
    ..To study the efficacy and complications of low dose indomethacin in the reduction of major intraventricular hemorrhage (IVH) in very low birth weight (VLBW) babies...
  38. ncbi Multiple cerebral microbleeds: MRI marker of a diffuse hemorrhage-prone state
    Julio A Chalela
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, Room B1D733, MSC 1063, Bethesda, MD 20892 1063, USA
    J Neuroimaging 14:54-7. 2004
    Recent reports have indicated that cerebral microbleeds (CMBs) detected on gradient-echo (GRF) magnetic resonance imaging may be a risk factor for therapy related intracranial hemorrhages (ICHs).
  39. ncbi Clinical importance of microbleeds in patients receiving IV thrombolysis
    W Kakuda
    Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA, USA
    Neurology 65:1175-8. 2005
    ..Cerebral microbleeds (MBs) detected on gradient echo (GRE) imaging may be a risk factor for hemorrhagic complications in patients with stroke treated with IV tissue plasminogen activator (tPA)...
  40. ncbi Spontaneous superficial parenchymal and leptomeningeal hemorrhage in term neonates
    Amy H Huang
    Department of Radiology, Brigham and Women s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA, USA
    AJNR Am J Neuroradiol 25:469-75. 2004
    ..In this study, we review the clinical and neuroimaging features of healthy term neonates presenting with spontaneous superficial parenchymal and leptomeningeal (ie, subpial or subarachnoid) hemorrhage...
  41. ncbi Early biomarkers of stroke
    Mark A Reynolds
    Biosite Incorporated, 11030 Roselle St, San Diego, CA 92121 Duke University Medical Center, Box 2900, Durham, NC 27710, USA
    Clin Chem 49:1733-9. 2003
    ..The ability to correlate blood-borne protein biomarkers with stroke phenotypes would aid in the development of such rapid tests...
  42. ncbi Migraine, headache, and the risk of stroke in women: a prospective study
    T Kurth
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215 1204, USA
    Neurology 64:1020-6. 2005
    ..Migraine and headache in general have been associated with subsequent risk of stroke, primarily in retrospective case-control studies. Prospective data evaluating the association between specific headache forms and stroke are sparse...
  43. doi Neurologic outcome in neonatal temporal lobe hemorrhagic venous infarcts
    Laurel Slaughter
    Division of Child Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Child Neurol 24:1236-42. 2009
    ..We conclude that neonatal temporal lobe hemorrhagic infarct secondary to suspected superficial temporal venous thrombosis appears to have a good clinical outcome. This is surprising, given the dramatic imaging and clinical presentations...
  44. ncbi Hypertensive pontine microhemorrhage
    Jee Hyang Jeong
    Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Stroke 33:925-9. 2002
    ..This study investigated whether the topography of hypertensive pontine microhemorrhages (hPMHs) resembles that of larger primary pontine hemorrhages...
  45. ncbi A review of genetic causes of ischemic and hemorrhagic stroke
    Martijn Tonk
    Department of Neurology, Leiden University Medical Centre, The Netherlands
    J Neurol Sci 257:273-9. 2007
    ..Animal model of stroke can also provide valuable information on genetic factors involved in stroke predisposition. In this review, the focus lies on monogenic forms of stroke that can serve as models to study the more common phenotypes...
  46. ncbi Neonatal complications of vacuum-assisted delivery
    Colin Simonson
    Department of Obstetrics and Gynaecology, Centre Hospitalier Universitaire Saint Pierre, Université Libre de Buxelles, Brussels, Belgium
    Obstet Gynecol 109:626-33. 2007
    ....
  47. ncbi Intracerebellar hemorrhage in premature infants: sonographic detection and outcome
    Hanna Müller
    Division of Neonatology, Department of Pediatrics, University of Heidelberg, Germany
    J Perinat Med 35:67-70. 2007
    ..Intracerebellar hemorrhage is a rarely confirmed diagnosis in preterm infants in comparison to peri-/intraventricular hemorrhage. This study evaluates the incidence of intracerebellar hemorrhage and neurological outcome in preterm infants...
  48. ncbi Stroke after bone marrow transplantation: frequency, aetiology and outcome
    W M Coplin
    Division of Pulmonary and Critical Care Medicine and the Department of Neurology, University of Washington, Seattle, Washington, USA
    Brain 124:1043-51. 2001
    ..Stroke occurs relatively frequently (incidence almost 3%) after BMT, has a relatively high frequency of infection-triggered events, has a neurological outcome not easily predicted from available data and is often fatal...
  49. doi Intracranial hemorrhage in term newborns: management and outcomes
    Surya N Gupta
    Department of Pediatric Neurology, Penn State University College of Medicine, Milton S Hershey Medical Center, Hershey, Pennsylvania, USA
    Pediatr Neurol 40:1-12. 2009
    ....
  50. ncbi Risk factors for intracranial hemorrhage among full-term infants: a case-control study
    Balraj S Jhawar
    Department of Neurosurgery, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada
    Neurosurgery 52:581-90; discussion 588-90. 2003
    ..To investigate the cause of intracranial hemorrhage among full-term infants...
  51. pmc Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis
    Gordon R Bernard
    Division of Allergy, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Crit Care 7:155-63. 2003
    ....
  52. ncbi Recombinant factor VIIa for rapid reversal of warfarin anticoagulation in acute intracranial hemorrhage
    William D Freeman
    Department of Neurology, Mayo Clinic College of Medicine, Jacksonville, Fla 32224, USA
    Mayo Clin Proc 79:1495-500. 2004
    ..To assess the effects of recombinant factor VIIa (rFVIIa) on hemorrhage volume and functional outcomes in warfarin-related acute intracranial hemorrhage (ICH), which has a 30-day mortality of more than 50%...
  53. ncbi Intracranial hemorrhage following bone marrow transplantation: an autopsy study of 58 patients
    L F Bleggi-Torres
    Department of Pathology, Hospital de Clinicas, University of Parana, Curitiba, Brazil
    Bone Marrow Transplant 29:29-32. 2002
    ..011). We conclude that ICH is common and has a significant mortality rate following BMT...
  54. ncbi Predictors of clinical improvement, angiographic recanalization, and intracranial hemorrhage after intra-arterial thrombolysis for acute ischemic stroke
    J I Suarez
    Department of Neurology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA
    Stroke 30:2094-100. 1999
    ..We sought to evaluate predictors of clinical outcome, angiographic success, and adverse effects after intra-arterial administration of urokinase for acute ischemic stroke...
  55. ncbi Prognostic predictors of thalamic hemorrhage
    S D Shah
    Department of Neurology, Sanjay Gandhi Postgraduate, Institute of Medical Sciences, Lucknow, India
    J Clin Neurosci 12:559-61. 2005
    ....
  56. ncbi Intracranial hemorrhage in asymptomatic neonates: prevalence on MR images and relationship to obstetric and neonatal risk factors
    Christopher B Looney
    Department of Psychiatry, CB No 7160, 7025A Neurosciences Hospital, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7160, USA
    Radiology 242:535-41. 2007
    ..To retrospectively evaluate the prevalence of neonatal intracranial hemorrhage (ICH) and its relationship to obstetric and neonatal risk factors...
  57. ncbi Prolonged latency after preterm premature rupture of membranes: an evaluation of histologic condition and intracranial ultrasonic abnormality in the neonate born at <28 weeks of gestation
    Thomas F McElrath
    Division of Maternal Fetal Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 189:794-8. 2003
    ....
  58. pmc Pediatric endocarditis and stroke: a single-center retrospective review of seven cases
    Charu Venkatesan
    Division of Neurology, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614, USA
    Pediatr Neurol 38:243-7. 2008
    ..Routine surveillance for mycotic aneurysms in patients with new neurologic deficits, and the use of aspirin, should be considered in the medical management...
  59. ncbi Complications of intracranial pressure monitoring in children with head trauma
    Richard C E Anderson
    Primary Children s Medical Center, University of Utah, Department of Neurosurgery, Salt Lake City, Utah, USA
    J Neurosurg 101:53-8. 2004
    ..The purpose of this study was to examine a consecutive series of children with TBI and compare the incidence of complications after placement of an EVD, a fiberoptic intraparencyhmal monitor, or both...
  60. ncbi Craniotomy with cystoperitoneal shunting for treatment of intracranial arachnoid cysts in dogs
    Curtis W Dewey
    Department of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA
    Vet Surg 36:416-22. 2007
    ..To describe a technique of decompressive craniotomy with cystoperitoneal shunt (CPS) placement for treatment of canine intracranial arachnoid cyst (IAC), and to evaluate outcome in 4 dogs...
  61. ncbi MRI-guided, open trial of abciximab for ischemic stroke within a 3- to 24-hour window
    P D Mitsias
    Department of Neurology, Henry Ford Health Sciences Center, Detroit, Michigan, USA
    Neurology 65:612-5. 2005
    ..Treatment of sub-24-hour stroke with abciximab improves early post-treatment neurologic status and often attenuates ischemic lesion growth...
  62. ncbi Recurrent thalamic haemorrhage attributed to a cerebellar arteriovenous malformation
    R Sparing
    Department of Neurology, University of Cologne, Cologne, Germany
    Can J Neurol Sci 35:358-9. 2008
  63. ncbi [Thrombolytic therapy in acute ischemic stroke. Critical analysis of current knowledge]
    Veronica Murray
    Medicinska kliniken, Danderyds sjukhus, Stockholm
    Lakartidningen 101:662-8, 670-3. 2004
    ..Giving priority to new large randomized controlled trials is essential to achieve this knowledge...
  64. pmc Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison
    Julio A Chalela
    Medical University of South Carolina, Charleston, SC, USA
    Lancet 369:293-8. 2007
    ..We aimed to prospectively compare CT and MRI for emergency diagnosis of acute stroke...
  65. doi Natural history of dural arteriovenous shunts
    Michael Soderman
    Department of Neuroradiology, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
    Stroke 39:1735-9. 2008
    ..Present knowledge about the natural history of these lesions is limited, however. We investigated the incidences of intracranial hemorrhage, progressive dementia syndrome, and death in patients diagnosed in our neurovascular center...
  66. doi Intracranial hemorrhage in newborns with hemophilia: the role of screening radiologic studies in the first 7 days of life
    Angela R Smith
    Department of Pediatric Hematology, University of Minnesota, Minneapolis, MN 55455, USA
    J Pediatr Hematol Oncol 30:81-4. 2008
    ..On the basis of this series we found screening to be safe and effective in recognizing ICH. As a result of this approach, all ICHs were found when they were radiographically small and before the babies had neurologic symptoms...
  67. ncbi Treatment of intracranial and extracranial haemorrhages in a neonate with severe haemophilia B with recombinant factor IX infusion
    G M T Guilcher
    Department of Paediatrics, Janeway Children s Health and Rehabilitation Centre, Memorial University of Newfoundland, St John s, NL, Canada
    Haemophilia 11:411-4. 2005
    ..A neonate with severe haemophilia B was treated successfully with recombinant FIX through continuous infusion. A high rate of infusion was required and no complications were noted...
  68. ncbi Effect of posture on the perception of verticality in neglect patients
    Arnaud Saj
    Service de Rééducation Neurologique and EA 2691, Hôpital Swynghedauw, CHRU de Lille, France
    Stroke 36:2203-5. 2005
    ..These patients have only been assessed when sitting. We investigated the hypothesis that postural changes modulate visuohaptic SV deviation...
  69. ncbi Multimodal therapy for the treatment of severe ischemic stroke combining GPIIb/IIIa antagonists and angioplasty after failure of thrombolysis
    Alex Abou-Chebl
    Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Stroke 36:2286-8. 2005
    ..Multimodal rescue therapy combining mechanical disruption and platelet GPIIb/IIIa receptor antagonists may improve recanalization...
  70. ncbi [Imaging of neonatal brain disorders: doubts and certitudes]
    S Witte-Meyer
    Service d Imagerie Anténatale, de l Enfant et de la Femme, CHU Pellegrin, Place Amelie Raba Leon, 33076 Bordeaux Cedex, France
    Arch Pediatr 13:672-4. 2006
  71. ncbi Stroke risk factor, pattern and outcome in patients with cancer
    Y Y Zhang
    Department of Aged Care and Rehabilitation, Bankstown Lidcombe Hospital, Sydney, NSW, Australia
    Acta Neurol Scand 114:378-83. 2006
    ..To investigate risk factors, stroke pattern and outcome in stroke patients with cancer...
  72. ncbi Fetal intracranial hemorrhage (fetal stroke): report of four antenatally diagnosed cases and review of the literature
    Ying Fen Huang
    Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, Taiwan
    Taiwan J Obstet Gynecol 45:135-41. 2006
    ..However, the true incidence of ICH in utero has not been determined. We present our experience with four cases of fetal ICH (fetal stroke), which was detected prenatally by ultrasonography (US)...
  73. ncbi Leptomeningeal cyst due to vacuum extraction delivery in a twin infant
    L Bobinski
    Department of Neurosurgery, University Hospital, Linkoping, Sweden
    Acta Neurochir (Wien) 149:319-23; discussion 323. 2007
    ..During a follow-up period of 12 years the neurological and psychological development of the boy has been indistinguishable to that of his twin brother, indicating the satisfactory outcome of the treatment...
  74. ncbi [Intracranial hemorrhage in term newborn]
    Tomasz Tomasik
    Klinika Chorób Dzieci Katedry, Pediatrii Polsko Amerykański Instytut Pediatrii, Collegium Medicum, Uniwersytetu Jagiellonskiego, Krakow
    Przegl Lek 62:1227-35. 2005
    ..The improvements in perinatal care during last decade have changed clinical presentation of intracranial hemorrhage (ICH) among full-term newborns. New imaging techniques allow for diagnosis of ICH even in asymptomatic babies...
  75. ncbi A risk scoring system for prediction of haemorrhagic stroke
    S P Zodpey
    Department of Preventive and Social Medicine, Clinical Epidemiology Unit, Govt Medical College, Nagpur
    Indian J Public Health 49:218-22. 2005
    ..79 (95% Cl = 0.73-0.84). Thus to conclude, if substantiated by further validation, this scorincy system can be used to predict haemorrhagic stroke, thereby helping to devise effective risk factor intervention strategy...
  76. pmc Symptomatic intracranial haemorrhage after intra-arterial thrombolysis in acute ischaemic stroke: assessment of 294 patients treated with urokinase
    C Brekenfeld
    Institute of Diagnostic and Interventional Neuroradiology, Inselspital, University of Berne, CH 3010 Berne, Switzerland
    J Neurol Neurosurg Psychiatry 78:280-5. 2007
    ..The PROACT II trial showed that intra-arterial thrombolysis (IAT) is effective for treatment of acute ischaemic stroke attributable to M1 and M2 segment occlusions. Incidence of symptomatic intracranial haemorrhage (sICH) was 10%...
  77. ncbi Cerebral microhemorrhage
    Anand Viswanathan
    Department of Neurology, CHU Lariboisière, Assistance Publique des Hopitaux de Paris, France
    Stroke 37:550-5. 2006
    ..This review summarizes the pathophysiology, differential diagnosis, epidemiology, and clinical significance of cerebral microhemorrhages...
  78. ncbi Comparison of clinical diagnosis with computed tomography in ascertaining type of stroke
    Jehangir Khan
    Department of Medicine, Ayub Medical College and Ayub Teaching Hospital, Abbottabad
    J Ayub Med Coll Abbottabad 17:65-7. 2005
    ..This study was carried out to compare clinical diagnosis of stroke with Computed tomography (CT) scan findings in ascertaining the type of stroke (hemorrhagic or ischemic)...
  79. ncbi [The evaluation of the brain arteriovenous malformations' operative treatment in the clinical material of Silesian Medical University's Departament of Neurosurgery]
    Adam Rudnik
    Katedry i Kliniki Neurochirurgii Slaskiej Akademii Medycznej w Katowicach
    Wiad Lek 59:801-4. 2006
    ..The aim of this work is presentation of our results of surgical treatment of AVM and comparison with the results of radiosurgical and endovascular treatment presented by other authors in the literature...
  80. ncbi Acutely and retrospectively diagnosed perinatal stroke: a population-based study
    Rael Laugesaar
    Children s Clinic of Tartu University Hospital, Tartu, Estonia
    Stroke 38:2234-40. 2007
    ....
  81. ncbi Comparison of five MR sequences for the detection of acute intracranial hemorrhage
    Catherine Oppenheim
    Department of Neuroradiology, Sainte Anne Hospital, Paris V University, France
    Cerebrovasc Dis 20:388-94. 2005
    ..To evaluate the respective value of 5 MR sequences to distinguish between stroke patients with and without acute intracerebral hemorrhage (ICH)...
  82. ncbi [Neurologic complications in the immediate postoperative period after cardiac surgery. Role of brain magnetic resonance imaging]
    José L Pérez-Vela
    Servicio de Medicina Intensiva, Hospital Universitario 12 de Octubre, Madrid, Spain
    Rev Esp Cardiol 58:1014-21. 2005
    ..Our understanding of the pathogenesis, prevention, and management of these lesions is constantly developing...
  83. ncbi Craniotomy with prosthetic heart valves: a clinical dilemma
    J Caird
    Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland
    Br J Neurosurg 20:40-2. 2006
    ..The authors emphasize the risk of re-anticoagulation without postoperative imaging and the disadvantages of therapeutic dose, low molecular weight heparin in the postoperative period...
  84. ncbi Conservative management of spontaneous posterior fossa subdural hematoma in a neonate
    Haydar Usul
    Department of Neurosurgery, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
    J Clin Neurosci 12:196-8. 2005
    ..Diagnosis is with computed tomography and magnetic resonance imaging. We present a spontaneous posterior fossa subdural hematoma in a term neonate and discuss conservative management...
  85. ncbi Imaging perinatal brain injury in premature infants
    Jeffrey J Neil
    Department of Neurology, Washington University School of Medicine, St Louis, MO, USA
    Semin Perinatol 28:433-43. 2004
    ..Current guidelines regarding the application of these neuroimaging methods to the premature infant are discussed...
  86. ncbi Time lag to diagnosis of stroke in children
    Lidia V Gabis
    Department of Neurology, State University of New York at Stony Brook, Stony Brook, New York 11794 8790, USA
    Pediatrics 110:924-8. 2002
    ..We evaluated whether children who receive a diagnosis of stroke meet a major inclusion criterion for such trials, namely time to diagnosis of <3 to 6 hours...
  87. ncbi Analysis of the safety and efficacy of intra-arterial thrombolytic therapy in ischemic stroke
    Rejane C Lisboa
    Departments of Neurology, Northwestern University Medical School, Chicago, Illinois, USA
    Stroke 33:2866-71. 2002
    ..Intra-arterial thrombolytic therapy (IAT) may be a treatment option for patients with ischemic stroke. We analyzed the safety and efficacy of IAT on the basis of published data...
  88. ncbi [A clinical study on spontaneous intracranial hemorrhage in children]
    Jia lin Cai
    Zhonghua Er Ke Za Zhi 41:471-2. 2003
  89. ncbi Intraarterial thrombolytic therapy within 3 hours of the onset of stroke
    Eric C Bourekas
    Department of Radiology, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA
    Neurosurgery 54:39-44; discussion 44-6. 2004
    ..This study is the first retrospective analysis of a two-institution experience with IA thrombolysis within 3 hours of stroke onset...
  90. ncbi Carotid dissection with permanent and transient occlusion or severe stenosis: Long-term outcome
    C Kremer
    Department of Neurology, University Hospitals of Zürich Drs Kremer, Mosso, Georgiadis, Benninger, Baumgartner, Bern, Switzerland
    Neurology 60:271-5. 2003
    ..To compare the rate of ischemic events and intracranial hemorrhage in the long-term follow-up of patients with persistent and transient severe stenosis or occlusion of the internal carotid artery (ICA) due to spontaneous dissection (ICAD)...
  91. ncbi Intracranial haemorrhage among a population of haemophilic patients in Brazil
    S V Antunes
    Serviço de Hemofilia, Disciplina de Hematologia e Hemoterapia, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Haemophilia 9:573-7. 2003
    ..This prompt treatment will increase the chances of a better prognosis. Another impact measure consists in the administration of the deficient coagulation factor after every head trauma, even when considered minor...
  92. ncbi Are some patients likely to benefit from recombinant tissue-type plasminogen activator for acute ischemic stroke even beyond 3 hours from symptom onset?
    David M Kent
    Division of Clinical Care Research, Tufts New England Medical Center, Boston, Mass 02111, USA
    Stroke 34:464-7. 2003
    ....
  93. ncbi Stroke in children
    Sheffali Gulati
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
    Indian J Pediatr 70:639-48. 2003
    ..Mortality after stroke in children ranges from 20% to 30% depending on the location and the underlying cause. Residual neurological dysfunction is present in more than 50% of survivors...
  94. ncbi [Dural arteriovenous fistulas with intracranial hemorrhage: diagnostic and therapeutic aspects]
    U Dietrich
    Neuroradiologie, Krankenanstalten Gilead, Bielefeld
    Zentralbl Neurochir 64:12-8. 2003
    ..In the first case definite closure of a remnant of the fistula was refused, in the second no further therapy was recommended...
  95. pmc Visible infarction on computed tomography is an independent predictor of poor functional outcome after stroke, and not of haemorrhagic transformation
    J M Wardlaw
    Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, Scotland, UK
    J Neurol Neurosurg Psychiatry 74:452-8. 2003
    ....
  96. ncbi Central post-stroke pain or paresthesia in lenticulocapsular hemorrhages
    Jong S Kim
    Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea
    Neurology 61:679-82. 2003
    ..The mean score of the visual numerical scale was 5.6. The lesions involved the dorsal part of the posterior limb of the internal capsule, probably damaging the thalamocortical sensory pathway...
  97. ncbi Stroke in children
    Vinita Jain
    Sir Ganga Ram Hospital, New Delhi, India
    Indian J Pediatr 70:S23-7. 2003
    ..The treatment of stroke is largely for stabilization of the patient, but it is very important to know the cause to prevent future strokes. Use of heparin in ischemic stroke is very promising and thrombolytic therapy is under trial...
  98. ncbi Acquired aqueductal stenosis in preterm infants: an indication for neuroendoscopic third ventriculostomy
    D Scavarda
    Department of Pediatric Neurosurgery, Hopital des Enfants, La Timone, 13385 Marseille Cedex 05, France
    Childs Nerv Syst 19:756-9. 2003
    ..The object of this study is to demonstrate the delayed occurrence of aqueductal stenosis in preterm infants who have suffered from intraventricular hemorrhage (IVH) and to try to explain the mechanisms of this stenosis...
  99. ncbi Spontaneous intracranial haemorrhage in children: aetiology, presentation and outcome
    Andreas D Meyer-Heim
    Division of Paediatric Neurology, University Children s Hospital, Steinwiesstrasse 75, CH 8032 Zurich, Switzerland
    Brain Dev 25:416-21. 2003
    ..Mortality (25%, 8/32) and morbidity were considerable, particularly in infratentorial haemorrhages, in aneurysms, in children younger than 3 years and in those with underlying haematological disorders...
  100. ncbi Cerebrovascular disorders in children
    John Kylan Lynch
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, NIH DHHS, Building 10, Room 5S220, 10 Center Drive, MSC 1447, Bethesda, MD 20892 1447, USA
    Curr Neurol Neurosci Rep 4:129-38. 2004
    ..This review briefly describes the epidemiology, risk factors, evaluation, treatment, and outcome of stroke in children...
  101. ncbi Arteriovenous malformation of the genu of the corpus callosum
    Omid J Bendavid
    Division of Neurosurgery, Department of Surgery, University of Vermont College of Medicine, Burlington, VT, USA
    Pediatr Neurosurg 40:49-50. 2004

Research Grants123 found, 100 shown here

  1. COCAINE AND PERINATAL CEREBRAL AND UMBILICAL VESSELS
    Michael Schreiber; Fiscal Year: 1991
    ..Although most reports describe full-term babies, sick preterm babies are a highest risk for intracranial hemorrhages, in part because they have immature capillary vessels and because they may have impaired cerebral ..
  2. COCAINE AND PERINATAL CEREBRAL AND UMBILICAL VESSELS
    Michael Schreiber; Fiscal Year: 1992
    ..Although most reports describe full-term babies, sick preterm babies are a highest risk for intracranial hemorrhages, in part because they have immature capillary vessels and because they may have impaired cerebral ..
  3. Phase 2B Study of TNK in Acute Stroke
    E Haley; Fiscal Year: 2004
    ..1 mg/kg and 0.4 mg/kg without any symptomatic intracranial hemorrhages being observed...
  4. Phase 2B Study of TNK in Acute Stroke
    E Haley; Fiscal Year: 2005
    ..1 mg/kg and 0.4 mg/kg without any symptomatic intracranial hemorrhages being observed...
  5. Phase 2B Study of TNK in Acute Stroke
    E Haley; Fiscal Year: 2007
    ..1 mg/kg and 0.4 mg/kg without any symptomatic intracranial hemorrhages being observed...
  6. Phase 2B Study of TNK in Acute Stroke
    E Haley; Fiscal Year: 2006
    ..1 mg/kg and 0.4 mg/kg without any symptomatic intracranial hemorrhages being observed...
  7. Natural History and Treatment Response of AVMs
    ALEXANDER HALIM; Fiscal Year: 2002
    Brain arteriovenous malformations (BAVM) are usually detected only when the patient presents with intracranial hemorrhages, seizures, headaches, focal neurological deficits, or other disorders. A smaller number are detected incidentally...
  8. Risks of Warfarin for Elders with Atrial Fibrillation
    Margaret Fang; Fiscal Year: 2008
    ..Together, these projects will provide practical experience and form the basis for future studies that seek to improve the safety and use of anticoagulants in the oldest patients with atrial fibrillation. ..
  9. Anticoagulation Treatment and Long-Term Outcomes After Venous Thromboembolism
    Margaret C Fang; Fiscal Year: 2010
    ..This project will evaluate current treatment patterns for VTE, identify risk factors for adverse outcomes, and develop clinically applicable risk-stratification tools to help predict recurrent VTE and major hemorrhagic complications. ..
  10. Risks of Warfarin for Elders with Atrial Fibrillation
    Margaret Fang; Fiscal Year: 2007
    ..Together, these projects will provide practical experience and form the basis for future studies that seek to improve the safety and use of anticoagulants in the oldest patients with atrial fibrillation. ..
  11. White matter injury in germinal matrix hemorrhage
    Praveen Ballabh; Fiscal Year: 2010
    ..Hence, the proposed study will elucidate the mechanism of white matter injury in IVH and may lead to novel strategies in prevention of cerebral palsy in premature infants. ..
  12. Novel Therapies in Hemostasis and Transfusion
    James Bussel; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] WEILL CORNELL MEDICAL CENTER/NEW YORK PRESBYTERIAN HOSPITAL CRITIQUES [unreadable] [unreadable] [unreadable] [unreadable]..
  13. Pericytes in Pathogenesis of Germinal-Matrix Hemorrhage
    Praveen Ballabh; Fiscal Year: 2006
    ..Our data may help in understanding the etiology of GMH and may explain the basis of prenatal glucocorticoid therapy. It may also identify new strategies in the prevention and treatment of GMH. [unreadable] [unreadable]..
  14. MATRIX METALLOPROTEINASES AND NEURONS IN FOCAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 2008
    ..These studies are likely to lead to new testable therapeutic approaches to preserve mlcrovascular and neuron function which will have relevance to other vascular neuron degenerative disorders. ..
  15. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 2001
    ..These studies are a direct extension of completed work of this proposal, and are expected to add greatly to the understanding of how vascular ischemia affects neuron integrity with testable treatment strategies. ..
  16. Neurovascular Adhesion Receptors and Barrier Integrity
    Gregory Del Zoppo; Fiscal Year: 2009
    ..abstract_text> ..
  17. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 2002
    ..These studies are a direct extension of completed work of this proposal, and are expected to add greatly to the understanding of how vascular ischemia affects neuron integrity with testable treatment strategies. ..
  18. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 2003
    ..These studies are a direct extension of completed work of this proposal, and are expected to add greatly to the understanding of how vascular ischemia affects neuron integrity with testable treatment strategies. ..
  19. Neurovascular Adhesion Receptors and Barrier Integrity
    Gregory Del Zoppo; Fiscal Year: 2008
    ..abstract_text> ..
  20. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 2004
    ..These studies are a direct extension of completed work of this proposal, and are expected to add greatly to the understanding of how vascular ischemia affects neuron integrity with testable treatment strategies. ..
  21. Neurovascular Adhesion Receptors and Barrier Integrity
    Gregory Del Zoppo; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  22. MATRIX METALLOPROTEINASES AND NEURONS IN FOCAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 2007
    ..These studies are likely to lead to new testable therapeutic approaches to preserve mlcrovascular and neuron function which will have relevance to other vascular neuron degenerative disorders. ..
  23. Neurovascular Adhesion Receptors and Barrier Integrity
    Gregory Del Zoppo; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  24. Neurovascular Adhesion Receptors and Barrier Integrity
    Gregory Del Zoppo; Fiscal Year: 2007
    ..abstract_text> ..
  25. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 1999
    ..In view of clinical studies demonstrating successful cerebral arterial recanalization, the approaches in this proposal may have significant consequences for future acute stroke patient management and outcome. ..
  26. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 1992
    ..In view of clinical studies demonstrating successful cerebral arterial recanalization, the approaches in this proposal may have significant consequences for future acute stroke patient management and outcome...
  27. MICROVASCULAR OCCLUSIONS--ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 1990
    ..This approach may have significant consequences for acute stroke patient management...
  28. MICROVASCULAR OCCLUSIONS--ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 1991
    ..This approach may have significant consequences for acute stroke patient management...
  29. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 1993
    ..In view of clinical studies demonstrating successful cerebral arterial recanalization, the approaches in this proposal may have significant consequences for future acute stroke patient management and outcome...
  30. MICROVASCULAR OCCLUSION IN ACUTE FOCAL CEREBRAL ISCHEMIA
    Gregory Del Zoppo; Fiscal Year: 1999
    ..In view of clinical studies demonstrating successful cerebral arterial recanalization, the approaches in this proposal may have significant consequences for future acute stroke patient management and outcome. ..
  31. Neurovascular Adhesion Receptors and Barrier Integrity
    Gregory J del Zoppo; Fiscal Year: 2010
    ..abstract_text> ..
  32. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 2005
    ..In all, continued study of our cohort will efficiently provide powerful insights into optimizing stroke prevention strategies for the many older Americans with AF. ..
  33. Harvard Planning Grant for Institutional Clinical and Translational Science Award
    Daniel Singer; Fiscal Year: 2006
    ..We believe our planning process is specific, innovative yet disciplined, and should be robust. A full and competitive CTSA application will be produced in a timely manner. [unreadable] [unreadable] [unreadable]..
  34. Whole Genome Association Study of Migraine in Women
    ROBERT YUK LUNG ZEE; Fiscal Year: 2010
    ..Thus, we request funding to study the genomic of migraine using a whole genome approach and to evaluate gene-environment interactions. ..
  35. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 2000
    ..comparison of the quality of anticoagulation provided by anticoagulation units versus that of primary physicians. The investigators state that this research should lead to important health and economic benefits for older Americans. ..
  36. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 2004
    ..In all, continued study of our cohort will efficiently provide powerful insights into optimizing stroke prevention strategies for the many older Americans with AF. ..
  37. The Significance of Intracranial Hemorrhage after Revascularization Therapy
    Pooja Khatri; Fiscal Year: 2007
    ..Therapies that restore blood flow to more patients, and do so more effectively and safely, are greatly needed to improve outcomes after stroke. [unreadable] [unreadable]..
  38. The Significance of Intracranial Hemorrhage after Revascularization Therapy
    Pooja Khatri; Fiscal Year: 2008
    ..Therapies that restore blood flow to more patients, and do so more effectively and safely, are greatly needed to improve outcomes after stroke. ..
  39. Whole Genome Association Study of Migraine in Women
    Tobias Kurth; Fiscal Year: 2008
    ..Thus, we request funding to study the genomic of migraine using a whole genome approach and to evaluate gene-environment interactions. ..
  40. Restless Legs Syndrome, Cardiovascular Risk Factors, and Cardiovascular Events
    Tobias Kurth; Fiscal Year: 2009
    ..Thus, this grant proposal request funding to study the association between RLS, CVD risk factors as well as CVD events. ..
  41. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 1999
    ..comparison of the quality of anticoagulation provided by anticoagulation units versus that of primary physicians. The investigators state that this research should lead to important health and economic benefits for older Americans. ..
  42. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 2002
    ..In all, continued study of our cohort will efficiently provide powerful insights into optimizing stroke prevention strategies for the many older Americans with AF. ..
  43. Restless Legs Syndrome, Cardiovascular Risk Factors, and Cardiovascular Events
    Tobias Kurth; Fiscal Year: 2008
    ..Thus, this grant proposal request funding to study the association between RLS, CVD risk factors as well as CVD events. ..
  44. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 2001
    ..In all, continued study of our cohort will efficiently provide powerful insights into optimizing stroke prevention strategies for the many older Americans with AF. ..
  45. Genetic influences on clinical outcome in brain arteriovenous malformations
    Helen Kim; Fiscal Year: 2008
    ..The Mentored Patient-Oriented Career Development Award and the advanced training milieu at UCSF will ensure the candidate's success in these endeavors. ..
  46. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 2003
    ..In all, continued study of our cohort will efficiently provide powerful insights into optimizing stroke prevention strategies for the many older Americans with AF. ..
  47. Restless Legs Syndrome, Cardiovascular Risk Factors, and Cardiovascular Events
    Tobias Kurth; Fiscal Year: 2010
    ..Thus, this grant proposal request funding to study the association between RLS, CVD risk factors as well as CVD events. ..
  48. Whole Genome Association Study of Migraine in Women
    Tobias Kurth; Fiscal Year: 2009
    ..Thus, we request funding to study the genomic of migraine using a whole genome approach and to evaluate gene-environment interactions. ..
  49. Vascular Mechanisms of Secondary Injury After TBI
    Claudia Robertson; Fiscal Year: 2007
    ..Effect of Erythropoietin on Anemia and Need for Transfusion Project 3. EDHF Following Traumatic Brain Injury Project 4. Neuroprotection of Erythropoietin Signaling in TBI ..
  50. In Vivo RNAi of Injury Signals After Brain Injury
    HELEN HELLMICH; Fiscal Year: 2007
    ..In turn, this may open up avenues for therapeutic manipulation of deleterious gene expression in human patients. [unreadable] [unreadable] [unreadable]..
  51. Consequences of Prolonged Febrile Seizures in Childhood
    Shlomo Shinnar; Fiscal Year: 2010
    ....
  52. fMRI of Language Recover Following Stroke in Adults
    Jerzy P Szaflarski; Fiscal Year: 2010
    ....
  53. Angiogenic Agents and Alveolar Injury
    Vineet Bhandari; Fiscal Year: 2007
    ..Determine the differences and the degree to which the response to hyperoxia-induced acute lung injury differs in adult, newborn and fetal mice with regard to VEGF, Angiopoietin 1 and Angiopoietin 2. ..
  54. Role of Angiogenic Agents in Alveolar Maturation and Injury
    Vineet Bhandari; Fiscal Year: 2009
    ....
  55. Prenatal Cocaine Exposure: Adolescent Follow-up
    Deborah Frank; Fiscal Year: 2007
    ..Such data can inform clinical interventions and public policy choices for care of youngsters with IUCE from infancy to adolescence. ..
  56. Occult Small Vessel Cerebrovascular Disease in High Risk Families
    Paul Nyquist; Fiscal Year: 2009
    ..It is also focused on the genes that may increase the susceptibility to small vessel disease in high risk families with a history of disease. ..
  57. Inflammatory and Immune Mechanisms of Atherosclerosis in HIV-Infected Women
    Robert C Kaplan; Fiscal Year: 2010
    ..g., lipids) over time due to changes in HAART and HIV disease stage, and how this impacts atherosclerosis. (End of Abstract) ..
  58. Dissociating Components of the Attentional Network in Neglect
    Christopher Rorden; Fiscal Year: 2007
    ..The present study tests these predictions by converging use of neuropsychology, functional MRI, and transcranial magnetic stimulation in normal observers. ..
  59. Epidemiology of IGF and Cardiovascular Events
    Robert Kaplan; Fiscal Year: 2005
    ....
  60. COCAINE EXPOSURE IN UTERO--ELEMENTARY SHCOOL FOLLOWUP
    Deborah Frank; Fiscal Year: 1999
    ..This data can inform public policy choices for care of cocaine exposed elementary school children nationwide. ..
  61. Hyperhomocysteinemia in Alzheimer's Disease
    Ramon Diaz Arrastia; Fiscal Year: 2002
    ..Each of these specific aims is essential to rationally design a large multicenter trial to determine whether polyvitamin therapy lowers AD risk. ..
  62. POTASSIUM CHANNELS AND CEREBRAL HEMODYNAMICS AFTER BRAIN
    William Armstead; Fiscal Year: 2002
    ..These studies may lead to therapies for brain injured children. ..
  63. Hyperhomocysteinemia in Alzheimer's Disease
    Ramon Diaz Arrastia; Fiscal Year: 2003
    ..Each of these specific aims is essential to rationally design a large multicenter trial to determine whether polyvitamin therapy lowers AD risk. ..
  64. GLUCAGON AND HEPATIC GENE EXPRESSION IN SURGICAL SEPSIS
    Brian Harbrecht; Fiscal Year: 2001
    ..These insights will contribute to uncovering the basic cellular mechanisms involved in multiple organ dysfunction and may lead to potential therapeutic approaches. ..
  65. Role of NOS3 in the Cerebrovascular Response to TBI
    Claudia Robertson; Fiscal Year: 2005
    ....
  66. COCAINE EXPOSURE IN UTERO--ELEMENTARY SHCOOL FOLLOWUP
    Deborah Frank; Fiscal Year: 2001
    ..These data will inform public Policy choices for the care of cocaine exposed pre and primary school children nationwide. ..
  67. PROGNOSIS OF CHILDREN WITH A FIRST UNPROVOKED SEIZURE
    Shlomo Shinnar; Fiscal Year: 2002
    ....
  68. GLUCAGON AND HEPATIC GENE EXPRESSION IN SURGICAL SEPSIS
    Brian Harbrecht; Fiscal Year: 2002
    ..These insights will contribute to uncovering the basic cellular mechanisms involved in multiple organ dysfunction and may lead to potential therapeutic approaches. ..
  69. PROGNOSIS OF CHILDREN WITH A FIRST UNPROVOKED SEIZURE
    Shlomo Shinnar; Fiscal Year: 1991
    ..Less than 10% of children with a first seizure are treated with long term medications at our institution. Therefore these results will reflect the true course of the disorder...
  70. GLUCAGON AND HEPATIC GENE EXPRESSION IN SURGICAL SEPSIS
    Brian Harbrecht; Fiscal Year: 2003
    ..These insights will contribute to uncovering the basic cellular mechanisms involved in multiple organ dysfunction and may lead to potential therapeutic approaches. ..
  71. Hepatocyte Nitric Oxide Synthase Regulation by Glucagon and Insulin
    Brian G Harbrecht; Fiscal Year: 2010
    ..By defining these mechanisms, we will provide a framework for understanding the basic cellular events in shock and sepsis, which may lead to novel cellular-based therapies for critically ill patients. ..
  72. NOVEL DEVICES FOR RAPID BLOOD COMPATIBILITY TESTING
    John Roback; Fiscal Year: 2004
    ..The results of the multi-center trial (to be completed during Phase Ill) will lead to an FDA 510(k) application. ..
  73. Iron Metabolism Alterations in Alzheimer's Disease
    Wolff Kirsch; Fiscal Year: 2002
    ..abstract_text> ..
  74. Plasminogen activators and NMDA after brain injury
    William Armstead; Fiscal Year: 2009
    ..Immunohistochemistry, detection of plasminogen activator and MAPK expression, and CBF determination by radiolabled microspheres will be performed. ..
  75. MOLECULAR ANALYSIS OF MYOTONIC DYSTROPHY
    SATYAKAM BHAGWATI; Fiscal Year: 2002
    ..This approach is designed to explore the function of these CTG/CUG repeat binding proteins and their possible role in the pathogenesis of DM. ..
  76. Adverse effects of RBC transfusions: A unifying hypothesis
    John Roback; Fiscal Year: 2009
    ..However, transfusions are associated with adverse effects. These studies will seek to determine why adverse outcomes happen after transfusion, and develop ways to improve blood collection and storage to minimize these outcomes. ..
  77. Iron Metabolism Alterations in Alzheimer's Disease
    Wolff Kirsch; Fiscal Year: 2003
    ..abstract_text> ..
  78. Immune Reactants, Cholesterol and Atherosclerosis
    ALLISON REISS; Fiscal Year: 2006
    ..abstract_text> ..
  79. NICHD Maternal Fetal Medicine Units Network
    Yoram Sorokin; Fiscal Year: 2006
    ..Our application and research proposal will reduce preterm delivery, and improve the health of pregnant women, their fetuses, and neonates. ..
  80. Vaccine-enhanced DLI to prevent cancer recurrence after stem cell transplantation
    John Roback; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  81. NICHD Maternal Fetal Medicine Units Network
    Yoram Sorokin; Fiscal Year: 2008
    ..Our application and research proposal will reduce preterm delivery, and improve the health of pregnant women, their fetuses, and neonates. ..
  82. POTASSIUM CHANNELS AND CEREBRAL HEMODYNAMICS AFTER BRAIN
    William Armstead; Fiscal Year: 2005
    ..These studies may lead to therapies for brain injured children. ..
  83. Plasminogen activators and cerebral ischemic injury
    William Armstead; Fiscal Year: 2007
    ....
  84. Immune Reactants, Cholesterol and Atherosclerosis
    ALLISON REISS; Fiscal Year: 2005
    ..abstract_text> ..