arteritis

Summary

Summary: Inflammation of an artery.

Top Publications

  1. ncbi Pathogenetic factors for excessive IgA production: Th2-dominated immune response in canine steroid-responsive meningitis-arteritis
    M Schwartz
    Department of Small Animal Medicine and Surgery, School of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    Vet J 187:260-6. 2011
  2. ncbi Lethal and severe coronary arteritis in DBA/2 mice induced by fungal pathogen, CAWS, Candida albicans water-soluble fraction
    Noriko Nagi-Miura
    Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Atherosclerosis 186:310-20. 2006
  3. ncbi The role of acute phase proteins in diagnosis and management of steroid-responsive meningitis arteritis in dogs
    M Lowrie
    Division of Companion Animal Sciences, Faculty of Veterinary Medicine, Institute of Comparative Medicine, University of Glasgow, Bearsden Road, Glasgow G611QH, UK
    Vet J 182:125-30. 2009
  4. ncbi Steroid responsive meningitis-arteritis: a prospective study of potential disease markers, prednisolone treatment, and long-term outcome in 20 dogs (2006-2008)
    M Lowrie
    Division of Companion Animal Sciences, Institute of Comparative Medicine, Faculty of Veterinary Medicine, University of Glasgow, Glasgow, UK
    J Vet Intern Med 23:862-70. 2009
  5. ncbi Aortic involvement in giant cell arteritis
    F Martinez-Valle
    Internal Medicine Department, Vall d Hebron University Hospital, Barcelona, Spain
    Autoimmun Rev 9:521-4. 2010
  6. ncbi Disproportionally strong increase of B cells in inflammatory cerebrospinal fluid of dogs with Steroid-responsive Meningitis-Arteritis
    M Schwartz
    Department of Small Animal Medicine and Surgery, School of Veterinary Medicine Hannover, Hannover, Germany
    Vet Immunol Immunopathol 125:274-83. 2008
  7. ncbi CARD15 mutations in familial granulomatosis syndromes: a study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy
    Xiaoju Wang
    Wayne State University School of Medicine, Detroit, Michigan, USA
    Arthritis Rheum 46:3041-5. 2002
  8. ncbi Cannabis arteritis revisited--ten new case reports
    P Disdier
    Service de Medecine Interne, CHU de la Timone, Marseille, France
    Angiology 52:1-5. 2001
  9. ncbi Selective CD11a upregulation on neutrophils in the acute phase of steroid-responsive meningitis-arteritis in dogs
    M Schwartz
    Department of Small Animal Medicine and Surgery, School of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    Vet Immunol Immunopathol 126:248-55. 2008
  10. ncbi A new animal model of continuous catheterization for investigating mechanisms of arteritis associated with chemotherapy
    Masaki Sudoh
    Division of Oral and Maxillofacial Biopathological Surgery, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University, 36 1 Nishicho, Yonago 683 8504, Japan
    Life Sci 74:3025-32. 2004

Detail Information

Publications226 found, 100 shown here

  1. ncbi Pathogenetic factors for excessive IgA production: Th2-dominated immune response in canine steroid-responsive meningitis-arteritis
    M Schwartz
    Department of Small Animal Medicine and Surgery, School of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    Vet J 187:260-6. 2011
    Canine steroid-responsive meningitis-arteritis (SRMA) is a systemic inflammatory disease with a predominant manifestation within the cervical meninges, increased immunoglobulin A (IgA) levels in serum and cerebrospinal fluid (CSF), and a ..
  2. ncbi Lethal and severe coronary arteritis in DBA/2 mice induced by fungal pathogen, CAWS, Candida albicans water-soluble fraction
    Noriko Nagi-Miura
    Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Atherosclerosis 186:310-20. 2006
    ..Intraperitoneal administration of CAWS induces coronary arteritis in various strains of inbred mice...
  3. ncbi The role of acute phase proteins in diagnosis and management of steroid-responsive meningitis arteritis in dogs
    M Lowrie
    Division of Companion Animal Sciences, Faculty of Veterinary Medicine, Institute of Comparative Medicine, University of Glasgow, Bearsden Road, Glasgow G611QH, UK
    Vet J 182:125-30. 2009
    ..Steroid-responsive meningitis arteritis (SRMA) is a well-recognised inflammatory disease of the dog, the diagnosis of which remains unsatisfactory based ..
  4. ncbi Steroid responsive meningitis-arteritis: a prospective study of potential disease markers, prednisolone treatment, and long-term outcome in 20 dogs (2006-2008)
    M Lowrie
    Division of Companion Animal Sciences, Institute of Comparative Medicine, Faculty of Veterinary Medicine, University of Glasgow, Glasgow, UK
    J Vet Intern Med 23:862-70. 2009
    Previous multidrug studies have identified the value of prednisolone in treating steroid responsive meningitis-arteritis (SRMA) and the potential value of acute phase proteins (APPs) and immunoglobulin A (IgA) in diagnosis and monitoring.
  5. ncbi Aortic involvement in giant cell arteritis
    F Martinez-Valle
    Internal Medicine Department, Vall d Hebron University Hospital, Barcelona, Spain
    Autoimmun Rev 9:521-4. 2010
    Giant cell arteritis (GCA) is a primary large-vessel vasculitis predominantly seen in the elderly that preferentially involves the external carotid artery and its branches...
  6. ncbi Disproportionally strong increase of B cells in inflammatory cerebrospinal fluid of dogs with Steroid-responsive Meningitis-Arteritis
    M Schwartz
    Department of Small Animal Medicine and Surgery, School of Veterinary Medicine Hannover, Hannover, Germany
    Vet Immunol Immunopathol 125:274-83. 2008
    Steroid-responsive Meningitis-Arteritis (SRMA) is a systemic inflammatory disease of juvenile to young adult dogs with a relapsing course and most prominent manifestation in the cervical meninges...
  7. ncbi CARD15 mutations in familial granulomatosis syndromes: a study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy
    Xiaoju Wang
    Wayne State University School of Medicine, Detroit, Michigan, USA
    Arthritis Rheum 46:3041-5. 2002
    ..To analyze the CARD15 gene in families with heritable multi-organ granulomatoses, including the original Blau syndrome kindred as well as other families with related granulomatous conditions...
  8. ncbi Cannabis arteritis revisited--ten new case reports
    P Disdier
    Service de Medecine Interne, CHU de la Timone, Marseille, France
    Angiology 52:1-5. 2001
    The purpose of this paper was to revisit the old concept of cannabis arteritis first described in the 1960s and report 10 new cases. Ten male patients, with a median age of 23...
  9. ncbi Selective CD11a upregulation on neutrophils in the acute phase of steroid-responsive meningitis-arteritis in dogs
    M Schwartz
    Department of Small Animal Medicine and Surgery, School of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    Vet Immunol Immunopathol 126:248-55. 2008
    Steroid-responsive meningitis-arteritis (SRMA) is a systemic inflammatory disease of juvenile to young adult dogs with a relapsing course and most prominent manifestation in the cervical meninges...
  10. ncbi A new animal model of continuous catheterization for investigating mechanisms of arteritis associated with chemotherapy
    Masaki Sudoh
    Division of Oral and Maxillofacial Biopathological Surgery, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University, 36 1 Nishicho, Yonago 683 8504, Japan
    Life Sci 74:3025-32. 2004
    ..has advantages for cancer therapy, intra-arterial chemotherapy is often interrupted by arterial damage due to arteritis. Therefore, an animal model must be developed to elucidate the mechanism of arteritis associated with continuous ..
  11. ncbi Concentrations of acute-phase proteins in dogs with steroid responsive meningitis-arteritis
    A Bathen-Noethen
    Department of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany
    J Vet Intern Med 22:1149-56. 2008
    ..Measurement of concentrations of acute-phase proteins (APPs) is used as an aid in the diagnosis of a variety of diseases in animals...
  12. pmc Interleukin-6, vascular endothelial growth factor and transforming growth factor beta 1 in canine steroid responsive meningitis-arteritis
    Arianna Maiolini
    Department of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany
    BMC Vet Res 9:23. 2013
    Steroid Responsive Meningitis-Arteritis (SRMA) is a common cause of inflammation of the canine central nervous system (CNS)...
  13. ncbi Do we need 18F-FDG-positron emission tomography as a functional imaging technique for diagnosing large vessel arteritis?
    M Wenger
    Clin Exp Rheumatol 21:S1-2. 2003
  14. ncbi Horner's syndrome and sixth nerve palsy due to herpes zoster ophthalmicus arteritis
    P K Pandey
    Eye (Lond) 19:224-6. 2005
  15. ncbi Induction of coronary arteritis with administration of CAWS (Candida albicans water-soluble fraction) depending on mouse strains
    Noriko Nagi-Miura
    Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, Japan
    Immunopharmacol Immunotoxicol 26:527-43. 2004
    ..We analyzed differences in the production of cytokines involved in the occurrence of coronary arteritis among mouse strains, C3H/HeN, C57BL/6, DBA/2 and CBA/J that were injected with CAWS at 4 mg/mouse for 5 ..
  16. ncbi Blau arteritis resembling Takayasu disease with a novel NOD2 mutation
    Raju P Khubchandani
    Division of Rheumatology, duPont Children s Hospital, 1600 Rockland Road, Wilmington, DE 19899, USA
    J Rheumatol 39:1888-92. 2012
    To put forward a new concept--Blau arteritis, a form of large-vessel vasculitis phenotypically related to Takayasu disease but genetically and clinically part of an expanded phenotype of Blau syndrome.
  17. ncbi Abdominal aortic aneurysms: an underestimated type of immune-mediated large vessel arteritis?
    Michael Schirmer
    Department of Internal Medicine, Innsbruck Medical University, Austria, Innsbruck Medical University, Austria
    Curr Opin Rheumatol 18:48-53. 2006
    ..To review recent studies on the immune-mediated pathogenesis of abdominal aortic aneurysms, opening a wide field for possible new therapeutic approaches...
  18. ncbi 18FDG imaging of giant cell arteritis: usefulness of whole-body plus brain PET
    Tarik Belhocine
    Eur J Nucl Med Mol Imaging 31:1055-6. 2004
  19. ncbi Neutrophil activation and arteritis induced by C. albicans water-soluble mannoprotein-beta-glucan complex (CAWS)
    Akiko Ishida-Okawara
    Department of Bioactive Molecules, National Institute of Infectious Diseases, Toyama 1 23 1, Tokyo, 162 8640, Japan
    Exp Mol Pathol 82:220-6. 2007
    We have established a mouse model which shows the symptoms of coronary arteritis after consecutive injections of CAWS, which is released from Candida albicans...
  20. ncbi Cannabis arteritis: a new case report and a review of literature
    I Peyrot
    Department of Dermatology, Teaching Hospital Pierre Zobda Quitman, Fort de France, France
    J Eur Acad Dermatol Venereol 21:388-91. 2007
    Cannabis arteritis manifests in cannabis users, independently of tobacco consumption. Around 50 cases were reported in the literature since the first description of this entity in 1960...
  21. ncbi Sympathetic cardiac modulation and vascular worsening in arteritis: a case report
    Lausanne B C C Rodrigues
    School of Physical Education, University of Pernambuco, Recife, Brazil
    J Vasc Nurs 30:21-3. 2012
    ..In this study, we assessed cardiac autonomic modulation by heart rate variability in two patients with arteritis who were followed up for 5 months...
  22. ncbi Pathological study of postcoronary arteritis in adolescents and young adults: with reference to the relationship between sequelae of Kawasaki disease and atherosclerosis
    K Takahashi
    Department of Pathology, Ohashi Hospital, Toho University School of Medicine, Meguro, Tokyo, Japan
    Pediatr Cardiol 22:138-42. 2001
    To clarify whether the cardiac sequelae of Kawasaki disease (KD), postcoronary arteritis lesions can become a risk factor for atherosclerosis of the coronary arteries, six autopsy cases of patients older than 15 years of age with ..
  23. pmc Extracellular hsp70 release in canine Steroid Responsive Meningitis-Arteritis
    Sarah A Moore
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA
    Vet Immunol Immunopathol 145:129-33. 2012
    ..the presence of ehsp70 in cerebrospinal fluid (CSF) and serum of dogs with Steroid Responsive Meningitis-Arteritis (SRMA), with the hypothesis that an ehsp70 response would occur, and might play a role in the pathogenesis of ..
  24. pmc Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis
    Wei Ma Krupa
    Department of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Pathol 161:1815-23. 2002
    ..In temporal arteries affected by giant cell arteritis, DCs are highly enriched and activated and have matured into fully differentiated cells producing the chemokines,..
  25. ncbi Large-vessel arteritis and myelodysplastic syndrome: report of two cases
    M Steurer
    Division of Haematology and Oncology, Innsbruck University Hospital, Innsbruck, Austria
    Eur J Haematol 73:128-33. 2004
    ..The first patient is a 67-yr-old male presenting with a massive large-vessel arteritis as primary manifestation of refractory anemia with excess of blasts type 1 (RAEB-1)...
  26. ncbi Surgical case of isolated pulmonary Takayasu's arteritis
    Ichiya Yamazaki
    Department of Cardiovascular Surgery, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
    Circ J 69:500-2. 2005
    Involvement of the pulmonary arteries is common in systemic Takayasu's arteritis, but pulmonary arteritis alone is very rare...
  27. pmc T cells in arteritis and atherosclerosis
    Cornelia M Weyand
    Kathleen B and Mason Lowance Center for Human Immunology and Rheumatology, Emory University, Atlanta, Georgia 30322, USA
    Curr Opin Lipidol 19:469-77. 2008
    ..Pro-inflammatory and anti-inflammatory T cells regulate master pathogenic pathways, providing a framework for novel immunotherapeutic strategies...
  28. ncbi Steroid-responsive meningitis-arteritis in the Pembroke Welsh corgi
    Giunio Bruto Cherubini
    Vet Rec 162:424. 2008
  29. ncbi Kawasaki disease in very young infants: high prevalence of atypical presentation and coronary arteritis
    Jacob Genizi
    Pediatric Department A, Ha Emek Medical Center, Afula, Israel
    Clin Pediatr (Phila) 42:263-7. 2003
  30. ncbi Radiation arteritis: a contraindication to carotid stenting?
    Clinton D Protack
    Center for Vascular Disease, Department of Surgery, University of Rochester, Rochester, NY 14642, USA
    J Vasc Surg 45:110-7. 2007
    Carotid artery stenting (CAS) for high-risk anatomic lesions is accepted practice. Neck irradiation and radiotherapy-induced arteritis are common indications. The clinical outcomes of CAS for radiation arteritis have been poorly defined.
  31. ncbi Acute occlusive large vessel disease leading to fatal stroke in a patient with systemic lupus erythematosus: arteritis or atherosclerosis?
    Katrin L Conen
    Department of Medicine, University Hospital Bruderholz, Bruderholz, Switzerland
    Arthritis Rheum 54:908-13. 2006
    ....
  32. ncbi Superantigenic activity is responsible for induction of coronary arteritis in mice: an animal model of Kawasaki disease
    Trang T Duong
    Cancer and Blood Research Program, The Hospital for Sick Children Research Institute, Toronto, Ontario M5G 1X8, Canada
    Int Immunol 15:79-89. 2003
    ..Lactobacillus casei cell wall extract-induced coronary arteritis in mice mirrors KD in children. Here, we report that responses to L...
  33. ncbi Susceptibility loci to coronary arteritis in animal model of Kawasaki disease induced with Candida albicans -derived substances
    Toshiaki Oharaseki
    Department of Pathology, Ohashi Hospital, Toho University School of Medicine, Tokyo, Japan
    Microbiol Immunol 49:181-9. 2005
    We have established an animal model of coronary arteritis which is histopathologically similar to that observed in cases of Kawasaki disease (KD), is a well-known childhood vasculitis syndrome...
  34. ncbi The macrophage is the predominant inflammatory cell in renal allograft intimal arteritis
    Philip J Matheson
    Department of Renal Medicine, Wellington Hospital, Wellington, New Zealand
    Transplantation 79:1658-62. 2005
    Intimal arteritis defines acute vascular rejection in the Banff 97 schema. The arteritis is generally considered to be lymphocytic, although the cellular infiltrate in tubulitis is composed of both lymphocytes and macrophages...
  35. pmc Arteritis in a novel congenic strain of mice derived from MRL/Lpr lupus mice: genetic dissociation from glomerulonephritis and limited autoantibody production
    M Nose
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Am J Pathol 149:1763-9. 1996
    ..These results indicate that each of these two diseases, arteritis and glomerulonephritis, is under the control of different background gene(s), suggesting a different ..
  36. ncbi Classification and pathogenesis of arteritis in children
    M J Dillon
    Hospital for Sick Children, London, United Kingdom
    Toxicol Pathol 17:214-8. 1989
    ..It seems likely that, in KD at least, retroviruses may have an etiological role either by directly infecting endothelial cells or indirectly via T-cells, antibody, or immune complex formation...
  37. ncbi 18F-FDG positron emission tomography/computed tomography and the "underground map" appearance in imaging Horton's arteritis
    N Abdul Jalil
    Department of Radiology, Faculty of Medicine and Health Science, Radionuclide Imaging Unit, University Putra Malaysia, Serdang 43400, Malaysia
    Singapore Med J 49:e178-82. 2008
    ..Prior CT and magnetic resonance imaging were not helpful in providing a clinical diagnosis. The diagnosis was Horton's arteritis, and the patient responded well to high-dose steroids.
  38. ncbi Macrophages and T lymphocytes are the predominant cells in intimal arteritis of resected renal allografts undergoing acute rejection
    Hua Jun Sun
    The Key Laboratory of Pathobiology, Ministry of Education, China, Bethune Medical College, Jilin University, Changchun, Jilin Province, PR China
    Transpl Immunol 25:42-8. 2011
    ..Although there is recent evidence that macrophages play important roles in acute vascular rejection, less is known about the exact proportion of immunocytes in the intimal arteritis of renal allografts with unfavorable outcomes.
  39. ncbi Quantification of supra-aortic arterial wall inflammation in patients with arteritis using high resolution dynamic contrast-enhanced magnetic resonance imaging: initial results in correlation to [18F]-FDG PET/CT
    Clemens C Cyran
    Department of Clinical Radiology, University Hospitals Munich Campus Grosshadern, Ludwig Maximilians University Munich, Germany
    Invest Radiol 46:594-9. 2011
    ..tomography (PET)/computed tomography (CT), used in clinical routine to detect inflamed arteries in patients with arteritis, with high resolution dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) in its ability to measure ..
  40. ncbi Arterial rupture as the result of fungal arteritis after renal transplantation
    Umberto Baccarani
    Transplantation 76:266-9. 2003
  41. ncbi An update on steroid responsive meningitis-arteritis
    A Tipold
    Department of Small Animal Medicine and Surgery, School of Veterinary Medicine Hannover, Bischofsholer Damm 15, Hannover, Germany
    J Small Anim Pract 51:150-4. 2010
    ..Upregulation of IgA, induced by a Th2 immune response, also plays a central role in the pathogenesis of SRMA...
  42. ncbi Early and late presentations of radiation arteritis
    J Gregory Modrall
    Department of Surgery, University of Texas Southwestern Medical Center, Dallas 75235, USA
    Semin Vasc Surg 16:209-14. 2003
    ..Establishing a presumptive diagnosis of radiation arteritis (RA) is based on clinical history and the arteriographic appearance of lesions...
  43. ncbi Potential role of the adventitia in arteritis and atherosclerosis
    J N Wilcox
    Department of Medicine, Emory University School of Medicine, Atlanta GA 30322, USA
    Int J Cardiol 54:S21-35. 1996
    ..Adventitial reactions are common in atherosclerosis as well as arteritis. Experimental hypercholesterolemia in pigs and non-human primates stimulates the accumulation of inflammatory ..
  44. ncbi Images in cardiovascular medicine. Generalized large vessel arteritis visualized by 18fluorodeoxyglucose-positron emission tomography
    Martin Wenger
    Department of Nuclear Medicine, Innsbruck University Hospital, Innsbruck, Austria
    Circulation 107:923. 2003
  45. ncbi Obliterative arteritis with nitric oxide synthase and HLA-DR expression in Crohn's colitis
    K Yokoyama
    Department of Internal Medicine, School of Medicine, Kitasato University East Hospital, 2-1-1 Asamizo-dai, Sagamihara, Kanagawa 228-8520, Japan
    Hepatogastroenterology 48:401-7. 2001
    ..05-0.0001). Crohn's disease activity was positively correlated with the degree of obliterative arteritis. Granulomatous vasculitis was found exclusively in Crohn's disease (10 cases; 43.5%)...
  46. ncbi [Severe pulmonary artery involvement of Takayasu arteritis. 3 cases and review of the literature]
    O Bletry
    Service de Medecine Interne, Groupe Hospitalier Pitie Salpetriere, Paris
    Arch Mal Coeur Vaiss 84:817-22. 1991
    ..The main complications are pulmonary hypertension and massive haemoptysis. Surgery is possible in cases of stenosis of the right main pulmonary artery. The potential role of endoluminal angioplasty is discussed...
  47. ncbi Human pythiosis, a rare cause of arteritis: case report and literature review
    Narawudt Prasertwitayakij
    Department of Medicine, Chiang Mai University, Thailand
    Semin Arthritis Rheum 33:204-14. 2003
    To present a case of Pythium insidiosum arteritis and review reported cases of human pythiosis.
  48. pmc Analysis of granulomatous arteritis in MRL/Mp autoimmune disease mice bearing lymphoproliferative genes. The use of mouse genetics to dissociate the development of arteritis and glomerulonephritis
    M Nose
    Department of Pathology, Tohoku University School of Medicine, Sendai, Japan
    Am J Pathol 135:271-80. 1989
    MRL/Mp mice bearing the lymphoproliferation gene (lpr) spontaneously develop systemic granulomatous arteritis coincident with glomerulonephritis (GNP)...
  49. ncbi Eosinophilic arteritis with coronary aneurysms and stenoses
    Paul B Poommipanit
    UCLA Medical Center, Los Angeles, California, USA
    J Invasive Cardiol 17:266-9. 2005
  50. ncbi Histopathological features of murine systemic vasculitis caused by Candida albicans extract--an animal model of Kawasaki disease
    K Takahashi
    Department of Pathology, Ohashi Hospital, Toho University School of Medicine, 2 17 6, Ohashi, Meguro, Tokyo, 153 8515, Japan
    Inflamm Res 53:72-7. 2004
    ..We examined the histopathological features of systemic vasculitis caused in mice by injection of a Candida albicans ( C. albicans) extract and investigated the principal genetic roles in the development of vasculitis...
  51. ncbi Sudden death in a 21-year-old man caused by thrombosed coronary aneurysm: late sequelae or a very late onset of Kawasaki disease?
    Giovanni Bartoloni
    Department of Pathology and Forensic Pathology, University of Catania Medical School, Catania, Italy
    Cardiovasc Pathol 11:318-21. 2002
    ..such as fever, mucositis, cervical lymphoadenopathy and skin rash, associated with coronary aneurysms or arteritis are diagnostic...
  52. ncbi Detection of alterations in brain glucose metabolism by positron emission tomography in Takayasu's arteritis
    Stefan M Weiner
    Eur J Nucl Med Mol Imaging 31:300-2. 2004
  53. ncbi Use of magnetic resonance imaging to differentiate optic neuritis and nonarteritic anterior ischemic optic neuropathy
    Joseph F Rizzo
    Department of Ophthalmology, Harvard Medical School and the Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthalmology 109:1679-84. 2002
    ..To determine if magnetic resonance imaging (MRI) of the optic nerves obtained during the acute phase can distinguish patients with optic neuritis (ON) from those with nonarteritic anterior ischemic optic neuropathy (NAION)...
  54. ncbi Imaging of large vessel vasculitis with (18)FDG PET: illusion or reality? A critical review of the literature data
    Tarik Belhocine
    Department of Nuclear Medicine, A Z Middelheim Hospital, 2020 Antwerp, Belgium
    Eur J Nucl Med Mol Imaging 30:1305-13. 2003
    ..Large vessel vasculitides such as giant cell arteritis and Takayasu arteritis are other examples that may potentially extend the field of (18)FDG PET indications...
  55. ncbi Non-arteritic anterior ischaemic optic neuropathy: evaluation of the brain and optic pathway by conventional MRI and magnetisation transfer imaging
    Maria I Argyropoulou
    Department of Radiology, Medical School, University of Ioannina, Greece
    Eur Radiol 17:1669-74. 2007
    ..05. NAION is characterised by decreased ON and chiasmatic size. The low MTR of the chiasm and brain associated with increased areas of WMH may be suggestive of demyelination and axonal damage due to generalised cerebral vascular disease...
  56. ncbi TNF-alpha is necessary for induction of coronary artery inflammation and aneurysm formation in an animal model of Kawasaki disease
    Joyce S Hui-Yuen
    Cancer Research Program, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada
    J Immunol 176:6294-301. 2006
    ..agent etanercept, as well as TNFRI knockout mice, are resistant to development of both coronary arteritis and coronary aneurysm formation...
  57. ncbi Presence of IFN-gamma does not indicate its necessity for induction of coronary arteritis in an animal model of Kawasaki disease
    Wesley C Chan
    Division of Cancer Research, Hospital for Sick Children Research Institute, Toronto, Canada
    J Immunol 173:3492-503. 2004
    ..study, we use an animal model of Kawasaki disease, Lactobacillus casei cell wall extract (LCWE)-induced coronary arteritis, to examine the role of IFN-gamma in the development of coronary artery lesions...
  58. ncbi Giant coronary artery aneurysm formation following meningococcal septicaemia
    S R Ford
    Division of Pediatric Cardiology, Rhode Island Hospital, Hoppin Street, Providence, RI 02903, USA
    Pediatr Cardiol 28:300-2. 2007
    ..We suggest that coronary vasculitis is a rare complication of meningococcal septicemia that should be included in the list of conditions known to elicit a Kawasaki-like inflammatory response...
  59. ncbi An autopsy case of isolated eosinophilic coronary periarteritis: a limited form of Churg-Strauss syndrome or a new entity?
    Kayano Taira
    Department of Cardiovascular Medicine, Yonezawa City Hospital, Yamagata
    Intern Med 44:586-9. 2005
    ..No significant vasculitis was found in any other organs. Based on the findings this seems to be the second reported case of isolated eosinophilic coronary periarteritis...
  60. ncbi Comparison of effects of abciximab versus eptifibatide on C-reactive protein, interleukin-6, and interleukin-1 receptor antagonist after coronary arterial stenting
    Atul Aggarwal
    Cardiac Unit, University of Vermont College of Medicine, 111 Colchester Avenue, Burlington, VT 05401, USA
    Am J Cardiol 91:1346-9. 2003
  61. ncbi Comparison between adventitial and intimal inflammation of ruptured and nonruptured atherosclerotic plaques in human coronary arteries
    Maria L Higuchi
    Heart Institute, Medical School, University of Sao Paulo, Sao Paulo, Brazil
    Arq Bras Cardiol 79:20-4. 2002
    ..To verify the possible role of adventitial inflammation in atherosclerotic plaque vulnerability and coronary artery remodelling...
  62. ncbi The primary vasculitides: a clinicopathologic correlation
    Navneet Narula
    Department of Pathology, University of California Medical Center, Irvine, Orange 92868, USA
    Am J Clin Pathol 124:S84-95. 2005
    ..Incorporation of antineutrophil cytoplasmic antibodies in defining the pathogenesis of vasculitis has been particularly useful in diagnosing those small vessel vasculitides that are life threatening and need immediate intervention...
  63. ncbi Association between carotid haemodynamics and inflammation in patients with essential hypertension
    S Manabe
    The Second Department of Internal Medicine, Ehime University School of Medicine, Toon City, Ehime, Japan
    J Hum Hypertens 19:787-91. 2005
    ..These results suggested that carotid haemodynamic parameters such as PI and RI are associated with atherosclerosis and inflammation in hypertensive patients...
  64. ncbi Elevated C-reactive protein is associated with an increased intima to media thickness of the common carotid artery
    Kerstin Winbeck
    Department of Neurology, Technical University of Munich, Germany
    Cerebrovasc Dis 13:57-63. 2002
    ..05)...
  65. ncbi Large vessel arteritis associated with human herpesvirus 6 infections
    S Toyabe
    Niigata University School of Medicine, Niigata, Japan
    Clin Rheumatol 21:528-32. 2002
    A 9-month-old boy presented with chronic arteritis of the aorta and its major branches. The clinical manifestations at onset of his illness were compatible with those of Kawasaki syndrome...
  66. ncbi Localized versus systemic vasculitis: diagnosis and management
    Robert J Quinet
    Department of Internal Medicine, Section on Rheumatology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    Curr Rheumatol Rep 5:93-9. 2003
    ..The physician's recognition of a localized versus systemic vasculitic process is important in terms of making the correct diagnosis, prescribing treatment, and arranging appropriate clinical follow-up...
  67. ncbi Comparison of cell-ELISA, flow cytometry and Western blotting for the detection of antiendothelial cell antibodies
    R Revelen
    Laboratory of Immunology, Brest University Medical School, France
    Clin Exp Rheumatol 20:19-26. 2002
    ..There is still great uncertainty in the detection of antiendothelial cell antibodies (AECA). The aim of our study was to compare the results obtained using different methods...
  68. ncbi Nonarteritic anterior ischemic optic neuropathy and tobacco smoking
    Sohan Singh Hayreh
    Department of Ophthalmology, College of Medicine, University of Iowa, Iowa City, Iowa 52242 1091, USA
    Ophthalmology 114:804-9. 2007
    ..To evaluate whether tobacco smoking may be a risk factor for development of nonarteritic anterior ischemic optic neuropathy (NA-AION)...
  69. ncbi Nonarteritic anterior ischemic optic neuropathy is associated with a specific platelet polymorphism located on the glycoprotein Ibalpha gene
    Ophira Salomon
    Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Ophthalmology 111:184-8. 2004
    ..To evaluate the association between platelet glycoprotein polymorphisms and the risks of single and second eye involvement with nonarteritic anterior ischemic optic neuropathy (NAION)...
  70. ncbi Three-month change in cerebral glucose metabolism in patients with nonarteritic ischemic optic neuropathy
    S Bose
    Department of Ophthalmology, University of California, Irvine, 118 Med Surge I, Irvine, CA 92697, USA
    Graefes Arch Clin Exp Ophthalmol 244:1052-5. 2006
    ..Positron emission tomography (PET) to determine the change in glucose metabolic rate in the visual cortex of patients with NAION versus age-matched controls was performed after 3 months' administration of pentoxifylline...
  71. ncbi Transvitreal optic neurotomy for nonarteritic anterior ischemic optic neuropathy
    Masoud Soheilian
    Department of Ophthalmology and Ophthalmic Research Center, Labbafinejad Medical Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Retina 23:692-7. 2003
    ....
  72. ncbi Indocyanine green and fluorescein angiography in nonarteritic anterior ischemic optic neuropathy
    Sibel Oto
    Department of Ophthalmology, Baskent University School of Medicine, Ankara, Turkey
    Retina 22:187-91. 2002
    ..To assess the value of indocyanine green angiography (ICGA) for demonstrating choroidal vascular abnormalities in patients with nonarteritic anterior ischemic optic neuropathy (NAION)...
  73. ncbi Familial non-arteritic anterior ischemic optic neuropathy
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242 1091, USA
    Graefes Arch Clin Exp Ophthalmol 246:1295-305. 2008
    ....
  74. pmc Correlations between retinal nerve fiber layer and visual field in eyes with nonarteritic anterior ischemic optic neuropathy
    Julio Deleon-Ortega
    Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Am J Ophthalmol 143:288-294. 2007
    ..To evaluate correlations between retinal nerve fiber layer (RNFL) thickness with visual field (VF) sensitivities in eyes with nonartertic anterior ischemic optic neuropathy (NAION)...
  75. ncbi Visual field abnormalities in nonarteritic anterior ischemic optic neuropathy: their pattern and prevalence at initial examination
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, College of Medicine, The University of Iowa, Iowa City, USA
    Arch Ophthalmol 123:1554-62. 2005
    ..To evaluate the pattern of various types of visual field defects and their prevalence at initial examination of nonarteritic anterior ischemic optic neuropathy (NA-AION)...
  76. ncbi Intravitreal triamcinolone acetonide injection for acute non-arteritic anterior ischaemic optic neuropathy
    Aylin Yaman
    Department of Ophthalmology, Dokuz Eylul University, Izmir, Turkey
    Clin Exp Optom 91:561-4. 2008
    ..Intravitreal triamcinolone injection may offer help in limiting the damage in this small group of patients with a relatively short history of visual loss due to NAION...
  77. ncbi Intravitreal triamcinolone acetonide for treatment of acute nonarteritic anterior ischemic optic neuropathy
    Jost B Jonas
    Department of Ophthalmology, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, 68167, Mannheim, Germany
    Graefes Arch Clin Exp Ophthalmol 245:749-50. 2007
    ..To report on the use of intravitreal triamcinolone acetonide as treatment for nonarteritic anterior ischemic optic neuropathy (NAION)...
  78. ncbi Nonarteritic anterior ischemic optic neuropathy: clinical characteristics in diabetic patients versus nondiabetic patients
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Ophthalmology 115:1818-25. 2008
    ..To investigate various aspects of nonarteritic anterior ischemic optic neuropathy (NA-AION) in patients with diabetes mellitus and to compare them with those in patients without diabetes mellitus...
  79. pmc Nonarteritic anterior ischemic optic neuropathy: natural history of visual outcome
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, College of Medicine University of Iowa, Iowa City, Iowa, USA
    Ophthalmology 115:298-305.e2. 2008
    ..To investigate systematically the natural history of visual outcome in nonarteritic anterior ischemic optic neuropathy (NAION)...
  80. pmc Non-arteritic anterior ischemic optic neuropathy: role of systemic corticosteroid therapy
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, IA, USA
    Graefes Arch Clin Exp Ophthalmol 246:1029-46. 2008
    ..To investigate systematically the role of systemic corticosteroid therapy in non-arteritic anterior ischemic optic neuropathy (NA-AION)...
  81. ncbi Non-arteritic ischaemic optic neuropathy (NAION) in patients under 50 years of age
    Márta Janáky
    Department of Ophthalmology, Faculty of Medicine, Albert Szent Györgyi Medical and Pharmaceutical Centre, University of Szeged, Szeged, Hungary
    Acta Ophthalmol Scand 83:499-503. 2005
    ..We intended to consider whether NAION at a relatively young age might comprise a separate pathological and diagnostic entity...
  82. ncbi Determining whether delayed nonarteritic ischemic optic neuropathy associated with cataract extraction is a true entity
    Ly T Nguyen
    Department of Ophthalmology, Denver Veterans Affairs Medical Center, Rocky Mountain Lions Eye Institute, University of Colorado Health Sciences Center, Aurora, Colorado, USA
    J Cataract Refract Surg 32:2105-9. 2006
    ....
  83. ncbi The morphology of an infarct in nonarteritic anterior ischemic optic neuropathy
    Rachel A Tesser
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA
    Ophthalmology 110:2031-5. 2003
    ..We studied the three-dimensional anatomic configuration of a NAION infarct to better elucidate its pathophysiology...
  84. ncbi Nonarteritic anterior ischemic optic neuropathy
    Niraj Desai
    School of Medicine, Medical College of Georgia, Augusta, GA 30912, USA
    J Clin Hypertens (Greenwich) 7:130-3. 2005
    ..There is no effective therapy to treat patients acutely or to prevent recurrence. After 6 months of careful follow-up, 57.3% of patients will have no significant change or worsening of their vision in the involved eye...
  85. ncbi Nonarteritic anterior ischemic optic neuropathy
    Michaela Kunz Mathews
    Department of Ophthalmology, University of Maryland, Baltimore, Maryland 21201, USA
    Curr Opin Ophthalmol 16:341-5. 2005
    ..The course of nonarteritic anterior ischemic optic neuropathy is also variable, often sequentially affecting the other eye...
  86. ncbi [Pulmonary segmental mediolytic arteriopathy]
    A M Muller
    Institut für Pathologie der Ruhr Universität Bochum, Berufsgenossenschaftliche Kliniken Bergmannsheil
    Pathologe 27:152-8. 2006
    ..Acute vasospasm (due to inappropriate reactions to catecholamine or endothelial dysfunction), as well as SMA as a precursor or subtype of fibromuscular dysplasia, are two theories still under discussion...
  87. ncbi Diffuse and active inflammation occurs in both vulnerable and stable plaques of the entire coronary tree: a histopathologic study of patients dying of acute myocardial infarction
    Alessandro Mauriello
    Department of Pathology, University of Rome Tor Vergata, Rome, Italy
    J Am Coll Cardiol 45:1585-93. 2005
    ..This study was undertaken to define and compare geographic coronary artery inflammation in patients who were dying of acute myocardial infarction (AMI), chronic stable angina (SA), and noncardiac causes (CTRL)...
  88. ncbi [Differential diagnosis of nonspecific aortic arteritis]
    A B Surgaliev
    Klin Med (Mosk) 80:60-6. 2002
    The article presents diagnostic criteria for nonspecific aortic arteritis proposed by K...
  89. ncbi Circulating oxidized low-density lipoprotein is associated with echolucent plaques in the femoral artery independently of hsCRP in 61-year-old men
    Vilborg Sigurdardottir
    The Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska University Hospital, Goteborg University, S 413 45 Gothenburg, Sweden
    Atherosclerosis 190:187-93. 2007
    ....
  90. ncbi Myocardial thievery: the coronary-subclavian steal syndrome
    Thomas J Takach
    Department of Cardiovascular Surgery, The Texas Heart Institute, St Luke s Episcopal Hospital, Houston, Texas, USA
    Ann Thorac Surg 81:386-92. 2006
    ....
  91. ncbi Segmental arterial mediolysis with accompanying venous angiopathy: a clinical pathologic review, report of 3 new cases, and comments on the role of endothelin-1 in its pathogenesis
    Richard E Slavin
    Cascade Pathology Group, Legacy Portland Hospitals, Emanuel Hospital and Health Center, Portland, Oregon, USA
    Int J Surg Pathol 15:121-34. 2007
    ..ET-1 may be indirectly play a role in SAM by cross-talking and potentiating the activities of other vasoconstrictors such as norepinephrine and by orchestrating its reparative phase...
  92. ncbi Myocardial infarction in young patients (< or =35 years of age) with systemic lupus erythematosus: a case report and clinical analysis of the literature
    C Korkmaz
    Division of Rheumatology, Department of Internal Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey
    Lupus 16:289-97. 2007
    ..involvement type (Group I: normal coronary artery or coronary thrombosis (n = 16); Group II: coronary aneurysm/arteritis (n = 12); Group III: coronary atherosclerosis (n = 22))...
  93. ncbi Systemic vascular disease in male B6C3F1 mice exposed to particulate matter by inhalation: studies conducted by the National Toxicology Program
    Carolyn F Moyer
    Pathology Associates, Raleigh, North Carolina 27606, USA
    Toxicol Pathol 30:427-34. 2002
    ..The results showed that high-dose males developed significantly increased incidences of coronary and renal arteritis over controls in 2 of the 9 studies (indium phosphide and cobalt sulfate heptahydrate), while marginal increases ..
  94. ncbi Endothelin antagonist-induced coronary and systemic arteritis in the beagle dog
    Huw B Jones
    Safety Assessment, AstraZeneca UK Ltd, Alderley Park, Macclesfield SK10 4TG, Cheshire, United Kingdom
    Toxicol Pathol 31:263-72. 2003
    ..Both drugs produced arteritis in small- and medium-sized coronary arteries after single or multiple doses, some of which were at or below the ..
  95. ncbi Adventitial inflammation: a possible pathogenic link to the instability of atherosclerotic plaque
    Cheng Lin Hu
    Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China
    Med Hypotheses 68:1262-4. 2007
    ..Chlamydia pneumoniae is directly involved in the development of adventitial and plaque inflammation (pan-arteritis), leading to plaque rupture. Adventitial O(2)(-) may also play an extensive role in the control of vascular tone...
  96. ncbi [Current issues regarding the complications of non-specific aorto-arteritis]
    A B Sugraliev
    Klin Med (Mosk) 82:15-8. 2004
  97. ncbi F-18 FDG PET-CT imaging in the care-management of a patient with pan-aortitis and coronary involvement
    Luca Ceriani
    Departments of Nuclear Medicine, EOC Regional Hospital of Bellinzona, CH 6500 Bellinzona, Switzerland
    Clin Nucl Med 32:562-4. 2007
  98. ncbi Acute myocardial infarction with normal coronary arteries in a young man with the Behcet's disease
    Feridun Kosar
    Int J Cardiol 99:355-7. 2005
    ..Although cardiac involvement is not infrequent as a manifestation of Behcet's disease, coronary arteritis is very rarely reported...
  99. ncbi Alterations of the sympathovagal balance evaluated by heart rate variability in a rare case of adult Still's disease
    Luigi Baratta
    Dipartimento di Medicina Clinica, Università degli Studi La Sapienza di Roma
    Ann Ital Med Int 19:193-7. 2004
    We present a rare case of adult Still's disease with cardiac involvement (myocarditis and coronary arteritis)...
  100. ncbi A case of multiple immunoglobulin G4-related periarteritis: a tumorous lesion of the coronary artery and abdominal aortic aneurysm
    Yasushi Matsumoto
    Department of Cardiovascular Surgery, National Hospital Organization, Kanazawa Medical Center, Kanazawa 920 8650, Japan
    Hum Pathol 39:975-80. 2008
    ..This case report suggested that IgG4-related disease can occur in the vascular system and manifest as an aneurysm or a periarterial mass lesion...
  101. ncbi Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha
    Harold J Ting
    Department of Biomedical Engineering, University of California, Davis, Genome and Biomedical Sciences Facility, Davis, CA 95616 5294, USA
    Circ Res 100:381-90. 2007
    ....

Research Grants40

  1. Serpin Modulation of Inflammatory Vasculitis; Potential for Immunomodulatory Ther
    ALEXANDRA ROSE LUCAS; Fiscal Year: 2010
    ..addresses the more rare inflammatory vasculitic syndromes, Takayasu's disease (TKD) and Giant Cell Temporal Arteritis (GCTA)...
  2. Molecular probes for a vOTU from CCHFV using a fluorogenic peptide
    SCOTT DUSAN PEGAN; Fiscal Year: 2013
    ..the economically devastating ssRNA (+) Arteriviruses, Porcine Respiratory and Reproduction Syndrome and Equine Arteritis viruses...
  3. The role of Burkholderia in giant cell arteritis
    Curry Koening; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Giant cell arteritis (GCA) is a systemic inflammatory disease of the elderly that causes inflammation of large- and medium-sized blood vessels...
  4. Biodegradable Nanoparticles for Targeted Antibiotic Delivery
    Judith A Whittum-Hudson; Fiscal Year: 2012
    ..pneumoniae has been compellingly associated with atherosclerosis, inflammatory arthritis, and temporal arteritis, among several others...
  5. Role of Interferon-gamma in Viral Reactivation and Vasculitis
    SUSAN PRISCILLA CANNY; Fiscal Year: 2013
    ..pathology in the great vessels of mice bearing resemblance to human Kawasaki's disease and Takayasu's arteritis. The cytokine, interferon gamma (IFNy), prevents reactivation of YHV-68 from latency and protects the host from ..
  6. Innate Immune Mechanisms and TLRs in Bacterial Ligand-Induced Arteritis
    Moshe Arditi; Fiscal Year: 2012
    ..of innate immune signaling via Toll-like receptors (TLRs) in inflammatory diseases such as atherosclerosis and arteritis. We reported that injection of cell wall extracts from L...
  7. Assessment of deubiquitinating and deISGylating activity;specificity motifs amon
    SCOTT DUSAN PEGAN; Fiscal Year: 2012
    ..the economically devastating ssRNA (+) arteriviruses, Porcine Respiratory and Reproduction Syndrome and Equine arteritis. This proposal will determine whether deubiquitinating and deISGylating activity is conserved function of this ..
  8. Potential Role of IL-1B Therapies for Treatment of Vasculitis of Kawasaki Disease
    Moshe Arditi; Fiscal Year: 2013
    ..The injection of Lactobacillus casei cell wall extract (LCCWE) to C57BL/6 mice causes a focal coronary arteritis that histopathologically mimics the coronary lesions observed in KD patients...
  9. Innate Immunity and Mouse Model of Kawasaki Disease
    Danica Jenine Schulte; Fiscal Year: 2010
    ..heart disease in children, both the etiology and molecular mechanisms leading to the associated coronary arteritis remain unknown...
  10. Vasculitis Clinical Research Consortium
    Peter A Merkel; Fiscal Year: 2013
    ..The VCRC currently has over 500 patients in clinical research on the following 6 types vasculitis: giant cell arteritis. Takayasu's arteritis, polyarteritis nodosa, Wegener's granulomatosis, microscopic polyangiitis, and ..
  11. CONCURRENT PILOT STUDIES IN GIANT CELL ARTERITIS AND TAKAYASUS ARTERITIS TO EXAM
    Avery Gottfried; Fiscal Year: 2011
    This study will examine whether the medication abatacept is safe in the treatment of giant cell arteritis (GCA) and Takayasu's arteritis (TAK) and whether there is evidence of effectiveness to support pursuing this medication in ..
  12. Cytomegalovirus infection of blood vessels
    Fenyong Liu; Fiscal Year: 2005
    ..in replication in the aorta and is defective in inducing viral-associated vascular diseases including acute arteritis and atherosclerosis...
  13. GIANT CELL ARTERITIS AND BACTERIAL INFECTIONS
    John Stone; Fiscal Year: 2000
    Giant cell arteritis (GCA), the most common form of systemic necrotizing vasculitis, is a chronic inflammatory condition of unknown etiology that chiefly afflicts the elderly...
  14. Vascular Injury and Atherosclerosis During Herpesvirus *
    Herbert Virgin; Fiscal Year: 2005
    ..Like murine CMV, y,HV68 causes chronic vasculitis restricted to the great elastic arteries (elastic arteritis)...
  15. CD8 T Cells in Rheumatoid Arthritis
    Cornelia M Weyand; Fiscal Year: 2010
    ..The goal of this proposal is to understand how such anti-inflammatory lymphocytes function and how they can be harnessed as novel therapeutic reagents in RA. ..
  16. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2005
    ..abstract_text> ..
  17. Complement Receptor 2 as a Biomarker for Systemic Lupus Erythematosus
    SUSAN BOACKLE; Fiscal Year: 2007
    ..In addition, they will advance our understanding of the role of CR2 in the pathogenesis of SLE and provide insight into the mechanisms that contribute to the development of this disease. [unreadable] [unreadable] [unreadable]..
  18. Mechanisms of PAI-1 Induced Anti-Angiogenesis
    Mary J Mulligan Kehoe; Fiscal Year: 2011
    ....
  19. Prednisone Ocular Myasthenia Gravis Trial Planning Grant
    Mark Kupersmith; Fiscal Year: 2004
    ....
  20. CTLA-4 Blockade in GM-CSF Vaccinated Patients
    FRANK HODI; Fiscal Year: 2004
    ..abstract_text> ..
  21. Visual Dysfunction and Quality of Life in MS
    Laura Balcer; Fiscal Year: 2003
    ..This proposal will provide a crucial foundation for future studies of vision in MS that will involve longitudinal assessment. ..
  22. MELANOMA ANTIGENS INDENTIFIED FROM GMCSF VACCINATION
    FRANK HODI; Fiscal Year: 2002
    ..Further identification of immunogenic antigens in melanoma offers promise for future therapies. ..
  23. BIOLOGY OF HUMAN INTRAEPITHELIAL LYMPHOCYTES
    Ellen Ebert; Fiscal Year: 2002
    ..These studies will determine the mechanism of IEL chemotaxis toward secreted products of ECs, why IL-15 is more potent than IL-2 in inducing LAK activity by IELs, and how IL-10 and IL-12 augment this activity. ..
  24. Heavy Metal-Induced Autoimmunity
    DWIGHT KONO; Fiscal Year: 2005
    ....
  25. Mechanisms Linking Depression to Cardiovascular Risk
    Viola Vaccarino; Fiscal Year: 2010
    ..abstract_text> ..
  26. Functional Analysis of Complement Receptor 2 as a Lupus Susceptibility Gene
    Susan A Boackle; Fiscal Year: 2010
    ....
  27. Posttraumatic Stress Disorder and Cardiovascular Disease
    Viola Vaccarino; Fiscal Year: 2007
    ..Efforts toward the prevention, early identification and treatment of PTSD and the identification of factors that mediate its adverse effects could reduce morbidity and mortality from CVD. ..
  28. Longitudinal Assessment of Visual Function in MS
    Laura Balcer; Fiscal Year: 2007
    ....
  29. Clinical Research for Rare Diseases: Opportunities, Challenges, and Solutions
    Peter Merkel; Fiscal Year: 2007
    ..If this conference proves successful, we plan on having similar sessions attached to future RDCRC meetings. [unreadable] [unreadable] [unreadable]..
  30. Pathophysiologies Involving Hemostasis-related Genes
    Francis Castellino; Fiscal Year: 2008
    ..abstract_text> ..
  31. Cr2 as a Murine Lupus Susceptibility Gene
    SUSAN BOACKLE; Fiscal Year: 2007
    ..These studies will clarify the specific functions of CR2, impaired in the NZM2410 mouse model, that may impact on the development of autoimmune disease and thus be important targets for therapeutic interventions. ..
  32. Cell Cycle Inhibition in Systemic Autoimmunity
    DWIGHT KONO; Fiscal Year: 2009
    ..These studies should yield important new insights into the significance and role of p21 in systemic autoimmunity and in host response to foreign antigens. ..
  33. PATHOGENESIS OF MURINE SYSTEMIC LUPUS ERYTHEMATOSUS
    DWIGHT KONO; Fiscal Year: 2009
    ..Identification of the susceptibility genes and elucidation of their roles in the induction of lupus should provide significant insights into the etiopathogenesis of genetically-determined autoimmune diseases. ..
  34. Vasculitis Clinical Research Network (VCRN)
    Peter Merkel; Fiscal Year: 2008
    ..AIM 5. Build and contribute to an electronic website resource with substantive content for clinicians, researchers, and patients. ..
  35. Novel Clinical and Ocular Imaging Outcomes with Long-Term Follow-Up in MS
    Laura Balcer; Fiscal Year: 2010
    ..Aim 3: Determine how low-contrast letter acuity, RNFL thickness, and total macular volume impact vision specific and overall health-related quality of life (HRQOL) in longitudinal studies of MS and ON. ..
  36. Lipoproteins, HIV, and Antiretroviral Therapy in SMART
    Daniel Duprez; Fiscal Year: 2008
    ..This proposal will produce additional information that will enhance their disease-free survival rate. (End of Abstract) [unreadable] [unreadable] [unreadable]..
  37. Studies in Scleroderma and Cystic Fibrosis Osteoporosis
    Peter Merkel; Fiscal Year: 2005
    ..A unique seminar and a series of support services at the host institution will further complement the training program. ..