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| coronary diseaseSummarySummary: An imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Top Publications
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Publications
Prediction of coronary heart disease using risk factor categoriesP W Wilson
Framingham Heart Study, National Heart, Lung, and Blood Institute, Mass 01701, USA
Circulation 97:1837-47. 1998....
Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statinsC Baigent
Lancet 366:1267-78. 2005..These findings reinforce the need to consider prolonged statin treatment with substantial LDL cholesterol reductions in all patients at high risk of any type of major vascular event...
Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studiesAlexander Thompson
Lp PLA2 Studies Collaboration Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK
Lancet 375:1536-44. 2010..We investigated associations of circulating Lp-PLA(2) mass and activity with risk of coronary heart disease, stroke, and mortality under different circumstances...
Effects of torcetrapib in patients at high risk for coronary eventsPhilip J Barter
Heart Research Institute, Camperdown, Sydney, NSW, Australia
N Engl J Med 357:2109-22. 2007..We investigated whether torcetrapib, a potent CETP inhibitor, might reduce major cardiovascular events. The trial was terminated prematurely because of an increased risk of death and cardiac events in patients receiving torcetrapib...
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in womenSandeep Bansal
Donald W Reynolds Center for Cardiovascular Research, Brigham and Women s Hospital, Boston, MA 02215, USA
JAMA 298:309-16. 2007..Although triglyceride levels are typically obtained in the fasting state, postprandial hypertriglyceridemia may play an important role in atherosclerosis...
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged menHanna Maaria Lakka
Research Institute of Public Health, University of Kuopio, Finland
JAMA 288:2709-16. 2002..Despite its high prevalence, little is known of the prospective association of the metabolic syndrome with cardiovascular and overall mortality...
Adherence to a Mediterranean diet and survival in a Greek populationAntonia Trichopoulou
Department of Hygiene and Epidemiology, University of Athens Medical School, Athens, Greece
N Engl J Med 348:2599-608. 2003..Adherence to a Mediterranean diet may improve longevity, but relevant data are limited...
Relation between serum phosphate level and cardiovascular event rate in people with coronary diseaseMarcello Tonelli
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Circulation 112:2627-33. 2005..Given the biological importance of phosphorus, it is plausible that higher levels of serum phosphate within the normal range may also be associated with adverse outcomes...
Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE projectR M Conroy
Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland
Eur Heart J 24:987-1003. 2003..71 to 0.84. CONCLUSIONS: The SCORE risk estimation system offers direct estimation of total fatal cardiovascular risk in a format suited to the constraints of clinical practice...
DS14: standard assessment of negative affectivity, social inhibition, and Type D personalityJohan Denollet
Medical Psychology, Department of Psychology and Health, Tilburg University, PO Box 90153, 5000 LE Tilburg, The Netherlands
Psychosom Med 67:89-97. 2005..This study reports on the Type D Scale-14 (DS14) as a standard measure of NA, SI, and Type D...
Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studiesAmanda Nicholson
Department of Epidemiology and Public Health, University College London Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
Eur Heart J 27:2763-74. 2006..We quantified the effect of depression on CHD, assessing the extent of confounding by coronary risk factors and disease severity...
Collaborative care for patients with depression and chronic illnessesWayne J Katon
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195 6560, USA
N Engl J Med 363:2611-20. 2010..We conducted a study to determine whether coordinated care management of multiple conditions improves disease control in these patients...
Genetic variants associated with Lp(a) lipoprotein level and coronary diseaseRobert Clarke
Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom
N Engl J Med 361:2518-28. 2009..The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease are incompletely understood.
Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trialsRod S Taylor
Department of Epidemiology and Public Health, University of Birmingham, Birmingham, United Kingdom
Am J Med 116:682-92. 2004..To review the effectiveness of exercise-based cardiac rehabilitation in patients with coronary heart disease...
Inflammation, atherosclerosis, and coronary artery diseaseGoran K Hansson
Karolinska Institute, Center for Molecular Medicine, Department of Medicine, Karolinska University Hospital, Stockholm, Sweden
N Engl J Med 352:1685-95. 2005
Fetal origins of adult disease: strength of effects and biological basisD J P Barker
Medical Research Council Environmental Epidemiology Unit, Southampton SO16 6YD, UK
Int J Epidemiol 31:1235-9. 2002....
HDL biogenesis and functions: role of HDL quality and quantity in atherosclerosisEirini M Tsompanidi
University of Patras Medical School, Department of Medicine, Pharmacology Unit, Rio, TK, Greece
Atherosclerosis 208:3-9. 2010..In addition, we discuss the significance of both HDL quality and quantity in assessing cardiovascular risk...
Contribution of high plasma triglycerides and low high-density lipoprotein cholesterol to residual risk of coronary heart disease after establishment of low-density lipoprotein cholesterol controlVincent J Carey
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 106:757-63. 2010..Thus, high TGs might have greater importance in patients with optimal rather than greater LDL cholesterol concentrations...
Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 studyOlga A Iakoubova
Celera, Alameda, California 9450, USA
J Am Coll Cardiol 51:449-55. 2008..We explored whether the benefit of intensive versus moderate statin therapy would be greater in carriers of KIF6 719Arg than in noncarriers...
Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trialsOlga A Iakoubova
Celera, Inc, Alameda, California 94502, USA
J Am Coll Cardiol 51:435-43. 2008....
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysisMitsuhiro Yokoyama
Kobe University, Kobe, Japan
Lancet 369:1090-8. 2007..We aimed to test the hypothesis that long-term use of eicosapentaenoic acid (EPA) is effective for prevention of major coronary events in hypercholesterolaemic patients in Japan who consume a large amount of fish...
Modelling the decreasing coronary heart disease mortality in Sweden between 1986 and 2002Lena Björck
Department of Emergency and Cardiovascular Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Eur Heart J 30:1046-56. 2009....
A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health StudyDov Shiffman
Celera, Alameda, California 94502, USA
J Am Coll Cardiol 51:444-8. 2008..We asked if carriers of the 719Arg allele of kinesin family member 6 (KIF6) have increased risk of coronary heart disease (CHD) in a cohort of initially healthy Caucasian American women...
Optimal medical therapy with or without PCI for stable coronary diseaseWilliam E Boden
Western New York Veterans Affairs Healthcare Network and Buffalo General Hospital SUNY, Buffalo, NY 14203, USA
N Engl J Med 356:1503-16. 2007....
Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trialsJ C LaRosa
Office of the President, State University of New York Health Science Center at Brooklyn, 11203, USA
JAMA 282:2340-6. 1999..Lowering low-density lipoprotein cholesterol (LDL-C) is known to reduce risk of recurrent coronary heart disease in middle-aged men. However, this effect has been uncertain in elderly people and women...
Extended-release niacin or ezetimibe and carotid intima-media thicknessAllen J Taylor
Cardiology Service, Walter Reed Army Medical Center, Washington, DC, USA
N Engl J Med 361:2113-22. 2009....
The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysisAmol Ashok Bahekar
Department of Cardiology, Chicago Medical School North Chicago Veterans Affairs Medical Center, Chicago, IL 60064, USA
Am Heart J 154:830-7. 2007..Previous studies have shown conflicting results as to whether periodontitis (PD) is associated with increased risk of coronary heart disease (CHD). The aim of the current study was to evaluate whether such an association exists...
Association of gene variants with incident myocardial infarction in the Cardiovascular Health StudyDov Shiffman
Celera, 1401 Harbor Bay Parkway, Alameda, CA 94502, USA
Arterioscler Thromb Vasc Biol 28:173-9. 2008....
White cell telomere length and risk of premature myocardial infarctionScott Brouilette
Division of Cardiology, Department of Medicine, University of Leicester, United Kingdom
Arterioscler Thromb Vasc Biol 23:842-6. 2003....
The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunctionR J Kim
Feinberg Cardiovascular Research Institute, and Department of Medicine, Northwestern University Medical School, Chicago, IL 60611 3008, USA
N Engl J Med 343:1445-53. 2000..We hypothesized that the results of contrast-enhanced MRI can be used to predict whether regions of abnormal ventricular contraction will improve after revascularization in patients with coronary artery disease...
Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatmentDominick J Angiolillo
Division of Cardiology, University of Florida, Shands Jacksonville, Jacksonville, Florida 32209, USA
J Am Coll Cardiol 48:298-304. 2006..This study sought to assess the influence of type 2 diabetes mellitus (T2DM) and the impact of hypoglycemic treatment (insulin vs. noninsulin) on platelet function profiles in patients treated with dual oral antiplatelet therapy...
Randomized controlled trial of an informatics-based intervention to increase statin prescription for secondary prevention of coronary diseaseWilliam T Lester
Laboratory of Computer Science, Massachusetts General Hospital, and Harvard Medical School, Boston, Mass, USA
J Gen Intern Med 21:22-9. 2006..Suboptimal treatment of hyperlipidemia in patients with coronary artery disease (CAD) is well documented. We report the impact of a computer-assisted physician-directed intervention to improve secondary prevention of hyperlipidemia...
Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adultsShaista Malik
Heart Disease Prevention Program, University of California, Irvine 92697, USA
Circulation 110:1245-50. 2004..Moreover, MetS more strongly predicts CHD, CVD, and total mortality than its individual components. CONCLUSIONS: CHD, CVD, and total mortality are significantly higher in US adults with than in those without MetS...
AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood InstituteSidney C Smith
Circulation 113:2363-72. 2006
Fetal programming of coronary heart diseaseDavid J P Barker
MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, SO16 6YD, Southampton, UK
Trends Endocrinol Metab 13:364-8. 2002..Coronary heart disease appears to be a developmental disorder that originates through two widespread biological phenomena, developmental plasticity and compensatory growth...
Depression as a predictor for coronary heart disease. a review and meta-analysisReiner Rugulies
Division of Occupational and Environmental Medicine, University of California, San Francisco, USA
Am J Prev Med 23:51-61. 2002..To review and quantify the impact of depression on the development of coronary heart disease (CHD) in initially healthy subjects...
Coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC) studyLloyd E Chambless
Department of Biostatistics, University of North Carolina, CB 8300, 137 East Franklin Street, Suite 400, Bank of America Center, Chapel Hill, NC 27514 4145, USA
J Clin Epidemiol 56:880-90. 2003..These factors substantially improved prediction of future CHD for men, less for women, and also increased attributable risks...
Reviewing myocardial silent ischemia: specific patient subgroupsTheodoros Xanthos
Department of Experimental Surgery and Surgical Research N S Christeas, Athens School of Medicine, Athens, Greece
Int J Cardiol 124:139-48. 2008....
Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam StudyHok Hay S Oei
Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
Circulation 111:570-5. 2005..In the present study, we investigated whether Lp-PLA2 is an independent predictor of coronary heart disease and ischemic stroke...
Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Münster (PROCAM) studyGerd Assmann
Institute of Arteriosclerosis Research at the University of Münster, Germany
Circulation 105:310-5. 2002..Although several scoring schemes have been suggested to calculate this profile, many omit information on important variables such as family history of coronary heart disease or LDL cholesterol...
Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trialsDariush Mozaffarian
Division of Cardiovascular Medicine and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
PLoS Med 7:e1000252. 2010..Additionally, some public health groups recommend lowering or limiting polyunsaturated fat (PUFA) consumption, a major potential replacement for SFA...
Association between type II secretory phospholipase A2 plasma concentrations and activity and cardiovascular events in patients with coronary heart diseaseWolfgang Koenig
Department of Internal Medicine II Cardiology, University of Ulm Medical Center, Albert Einstein Allee 23, Ulm, Germany
Eur Heart J 30:2742-8. 2009..We sought to evaluate whether systemic sPLA(2) is associated with prognosis in patients with coronary heart disease (CHD)...
Prediction of coronary heart disease risk in a general, pre-diabetic, and diabetic population during 10 years of follow-up: accuracy of the Framingham, SCORE, and UKPDS risk functions: The Hoorn StudyAmber A W A van der Heijden
EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
Diabetes Care 32:2094-8. 2009....
Beyond low-density lipoprotein cholesterol: respective contributions of non-high-density lipoprotein cholesterol levels, triglycerides, and the total cholesterol/high-density lipoprotein cholesterol ratio to coronary heart disease risk in apparently healtBenoit J Arsenault
Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Quebec, Canada
J Am Coll Cardiol 55:35-41. 2009....
Coronary calcium score improves classification of coronary heart disease risk in the elderly: the Rotterdam studySuzette E Elias-Smale
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
J Am Coll Cardiol 56:1407-14. 2010....
Including socioeconomic status in coronary heart disease risk estimationPeter Franks
Center for Healthcare Policy and Research, Sacramento, California, USA
Ann Fam Med 8:447-53. 2010..We examined whether hybrid SES measures (based on area measures of income and individual education) address this bias and derived an approach to incorporating SES information into treatment guidelines...
Integrating depression and chronic disease care among patients with diabetes and/or coronary heart disease: the design of the TEAMcare studyWayne Katon
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, United States
Contemp Clin Trials 31:312-22. 2010..This intervention is being tested in an NIMH-funded randomized controlled trial in a large integrated health plan...
Changes in residential proximity to road traffic and the risk of death from coronary heart diseaseWen Qi Gan
School of Environmental Health, The University of British Columbia, Vancouver, BC, Canada
Epidemiology 21:642-9. 2010..Residential proximity to road traffic is associated with increased coronary heart disease (CHD) morbidity and mortality. It is unknown, however, whether changes in residential proximity to traffic could alter the risk of CHD mortality...
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studiesNadeem Sarwar
Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort s Causeway, Cambridge CB1 8RN, UK
Lancet 375:1634-9. 2010..Whether triglyceride-mediated pathways are causally relevant to coronary heart disease is uncertain. We studied a genetic variant that regulates triglyceride concentration to help judge likelihood of causality...
Prospective analysis of traffic exposure as a risk factor for incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) studyHaidong Kan
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
Environ Health Perspect 116:1463-8. 2008..For people living close to busy roads, traffic is a major source of air pollution. Few prospective data have been published on the effects of long-term exposure to traffic on the incidence of coronary heart disease (CHD)...
Patient-reported health status in coronary heart disease in the United States: age, sex, racial, and ethnic differencesJipan Xie
Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Mailstop K 47, 4770 Buford Hwy NE, Atlanta, GA 30341 3717, USA
Circulation 118:491-7. 2008..Coronary heart disease (CHD) affects 15.8 million Americans. However, data on the national impact of CHD on health-related quality of life, particularly among people of different age, sex, racial, and ethnic groups, are limited...
Unrecognized non-Q-wave myocardial infarction: prevalence and prognostic significance in patients with suspected coronary diseaseHan W Kim
Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, Duke University, Durham, North Carolina, USA
PLoS Med 6:e1000057. 2009..The aim of this study was to investigate the prevalence and prognosis associated with non-Q-wave UMI identified by DE-CMR...
Benefits of statin therapy and compliance in high risk cardiovascular patientsJoel A Lardizabal
Division of Cardiology, Department of Medicine, University of California in San Francisco Fresno MEP, Fresno, CA, USA
Vasc Health Risk Manag 6:843-53. 2010..To fully reap the benefits of statin therapy, interventions which improve long-term treatment compliance in real-world settings should be encouraged...
Five common gene variants identify elevated genetic risk for coronary heart diseaseLance A Bare
Celera, Alameda, California 94502, USA
Genet Med 9:682-9. 2007....
Does the routine use of global coronary heart disease risk scores translate into clinical benefits or harms? A systematic review of the literatureStacey L Sheridan
Division of General Medicine and Clinical Epidemiology, University of North Carolina, Chapel Hill, NC, USA
BMC Health Serv Res 8:60. 2008..Guidelines now recommend routine assessment of global coronary heart disease (CHD) risk scores. We performed a systematic review to assess whether global CHD risk scores result in clinical benefits or harms...
Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk ≥ 5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authoritiesWolfgang Koenig
Department of Internal Medicine II Cardiology, University of Ulm Medical Center, Albert Einstein Allee 23, Ulm, Germany
Eur Heart J 32:75-83. 2011..However, as these are post hoc analyses, data describing these subgroups have not previously been available to the clinical community...
Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart StudyM De Lorgeril
Explorations Fonctionnelles Cardiorespiratoires et Métaboliques, CHU de Saint Etienne, France
Circulation 99:779-85. 1999..This report presents results of an extended follow-up (with a mean of 46 months per patient) and deals with the relationships of dietary patterns and traditional risk factors with recurrence...
Effect of pravastatin on malondialdehyde-modified low-density lipoprotein levels and coronary plaque regression as determined by three-dimensional intravascular ultrasoundShigemasa Tani
Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
Am J Cardiol 96:1089-94. 2005..In conclusion, these results suggest that the reduction in the MDA-LDL levels induced by pravastatin may serve as a novel marker of coronary atherosclerosis regression...
Alcohol consumption and cardiovascular mortality accounting for possible misclassification of intake: 11-year follow-up of the Melbourne Collaborative Cohort StudyLinton R Harriss
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
Addiction 102:1574-85. 2007..To investigate the relationship between usual daily alcohol intake, beverage type and drinking frequency on cardiovascular (CVD) and coronary heart disease (CHD) mortality, accounting for systematic misclassification of intake...
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trialJacques E Rossouw
Division of Women s Health Initiative, National Heart, Lung, and Blood Institute, 6705 Rockledge Dr, One Rockledge Ctr, Suite 300, Bethesda, MD 20817
JAMA 288:321-33. 2002..Despite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains uncertain...
Diet as preventive medicine in cardiologyM De Lorgeril
Laboratoire du Stress Cardiovasculaire et Pathologies Associées, UFR de Medecine et Pharmacie, Grenoble, France
Curr Opin Cardiol 15:364-70. 2000..Their use is now encouraged either as supplements or as part of a Mediterranean-type diet...
Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets studyPrakash Deedwania
Veterans Affairs Central California Healthcare System and University of California San Francisco School of Medicine, San Francisco, CA, USA
Lancet 368:919-28. 2006....
Long-term outcomes based on time-to-angioplasty in patients admitted with non-ST-segment elevation acute coronary syndromesMouaz Al-Mallah
Interventional Cardiovascular Fellowship, Henry Ford Heart and Vascular Institute, Cardiac Cath Lab, K-2, 2799 West Grand Blvd, Detroit, MI, USA
J Invasive Cardiol 17:251-5. 2005..04) after adjusting for confounding variables. CONCLUSION: In patients with NSTE-ACS and no contraindication to angiography, delayed angiography of more than 2 days of presentation was associated with increased mortality at 3 years...
Relation of atherothrombosis burden and volume detected by intravascular ultrasound to angiographic no-reflow phenomenon during stent implantation in patients with acute myocardial infarctionTakuji Katayama
The Cardiovascular Division, First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan
Am J Cardiol 97:301-4. 2006..013, respectively). In conclusion, high atherothrombotic burden and decreased plaque volume as detected by IVUS may be risk factors for development of the no-reflow phenomenon during stent implantation in patients with AMI...
Short- and long-term clinical outcome after drug-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: insights from the Rapamycin-Eluting and Taxus Stent Evaluated At Rotterdam Cardiology Hospital registries (RESMarco Valgimigli
Erasmus Medical Center, Rotterdam, The Netherlands
Circulation 111:1383-9. 2005..of major adverse cardiovascular events in patients undergoing percutaneous intervention for left main (LM) coronary disease is largely unknown...
Risk reduction of cardiac events by screening of unknown asymptomatic coronary artery disease in subjects with type 2 diabetes mellitus at high cardiovascular risk: an open-label randomized pilot studyEzio Faglia
Internal Medicine Unit, Diabetology Center, Policlinico Multimedica, Sesto San Giovanni, Milan, Italy
Am Heart J 149:e1-6. 2005..Evaluated the efficacy of reducing the risk of cardiac events by a preclinical diagnosis of CAD in subjects with type 2 diabetes mellitus with 2 or more cardiovascular risk factors...
Thoracic radiotherapy in patients with lymphoma and restenosis after coronary stent placementKathrin Schömig
Deutsches Herzzentrum, Technische Universität Munich, Munich, Germany
Catheter Cardiovasc Interv 70:359-65. 2007..The aim of this study was to assess the incidence of restenosis after coronary stenting in patients with lymphoma treated with thoracic radiation...
Myocardial infarction redefined: impact on case-load and outcome of patients with suspected acute coronary syndrome and nondiagnostic ECG at presentationAlberto Conti
Emergency Medicine Department, Chest Pain Unit, Azienda Ospedaliero, Universitaria Careggi, Florence, Italy
Int J Cardiol 111:195-201. 2006....
Plasma C-reactive protein and lipoprotein levels, and progression of coronary artery disease after myocardial infarction treated with thrombolysisPer Tornvall
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
Cardiology 104:65-71. 2005....
Effect of direct stent implantation on QTc dispersionYusuf Atmaca
Ankara University Faculty of Medicine, Department of Cardiology, Ankara, Turkey
Angiology 56:143-9. 2005....
Free Interleukin (IL)-18 levels, and the impact of IL18 and IL18BP genetic variation, in CHD patients and healthy menSimon R Thompson
Cardiovascular Genetics, Rayne Institute, University College London, WC1E 6JF, UK
Arterioscler Thromb Vasc Biol 27:2743-9. 2007..To investigate free interleukin-18 (fIL-18) levels, and variation within the IL-18 system genes, in heart surgery patients, and healthy men...
Relation between baseline risk and treatment decisions in non-ST elevation acute coronary syndromes: an examination of international practice patternsP Kaul
University of Alberta, Edmonton, Alberta, Canada
Heart 91:876-81. 2005..To examine whether ST segment depression influenced clinical decision making and whether there was international variation in the use of cardiac procedures across ST segment depression categories...
Alcohol consumption, atherosclerotic progression, and prognosis among patients with coronary artery bypass graftsKenneth J Mukamal
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Am Heart J 151:368-72. 2006..Although moderate drinking has been associated with lower mortality among patients after myocardial infarction, its relationship with prognosis and graft obstruction among patients with coronary artery bypass grafts is unknown...
[Acute coronary syndrome--ECG-changes without ST-elevation]Gabriel Christian Forselv
Det medisinske fakultet, Norges Teknisk Naturvitenskapelige Universitet, Trondheim
Tidsskr Nor Laegeforen 127:2230-2. 2007..Patients with acute coronary syndrome without ST-segment elevation in ECG have a serious prognosis with increased risk of a new myocardial infarction and death. The prognosis depends on the artery involved...
Coronary artery disease progression in patients who need repeat surgical revascularisation: the surgeon's point of viewAndreas Borowski
Clinic for Thoracic and Cardiovascular Surgery, University of Dusseldorf, Germany
J Cardiovasc Med (Hagerstown) 9:85-8. 2008..The purpose of this study was to evaluate changes in native coronary arteries in patients undergoing repeat myocardial revascularisation late (>3 years) after primary coronary artery bypass grafting (CABG)...
Stents versus coronary-artery bypass grafting for left main coronary artery diseaseKi Bae Seung
Catholic University of Korea, St Mary s Hospital, Gangnam, Korea
N Engl J Med 358:1781-92. 2008..However, there are limited data regarding the long-term outcomes of these two interventions for patients with unprotected left main coronary artery disease...
An evaluation of fluoroscopy time and correlation with outcomes after percutaneous coronary interventionEugenia Nikolsky
Columbia University Medical Center and the Cardiovascular Research Foundation, New York City, NY 10022, USA
J Invasive Cardiol 19:208-13. 2007..We evaluated short-term prognosis and resource utilization of consecutive patients treated with percutaneous coronary intervention (PCI) as a function of fluoroscopy time...
Value of electrocardiographically gated single-photon emission computed tomographic myocardial perfusion scintigraphy in a cohort of symptomatic postmenopausal womenJennifer H Mieres
New York University School of Medicine, New York, USA
Am J Cardiol 99:1096-9. 2007..001). In conclusion, results of this study indicate high diagnostic and prognostic accuracy for MPS in symptomatic postmenopausal women...
Potentially modifiable classic risk factors and their impact on incident myocardial infarction: results from the EPIC-Potsdam studyChristin Heidemann
Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
Eur J Cardiovasc Prev Rehabil 14:65-71. 2007..Prospective data on the importance of established risk factors for myocardial infarction in Germany are sparse...
Comparison of immediate and one-year outcome after coronary angioplasty of narrowing < 3 mm with those > or =3 mm ( the National Heart, Lung, and Blood Institute Dynamic Registry)J Al Suwaidi
Mayo Clinic and Foundation, Rochester, Minnesota, USA
Am J Cardiol 87:680-6. 2001....
Percutaneous coronary intervention in patients with a single remaining vesselDavide Tavano
San Raffaele Scientific Institute, Milan, Italy
Am J Cardiol 99:470-1. 2007..In conclusion, these data support percutaneous intervention as a realistic treatment option for this often highly symptomatic and difficult-to-treat patient cohort...
Factors predictive of cardiac events and restenosis after sirolimus-eluting stent implantation in small coronary arteriesCheol Whan Lee
Department of Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea
Catheter Cardiovasc Interv 69:821-5. 2007..Predictors of cardiac events and restenosis after sirolimus-eluting stent (SES) implantation in small coronary arteries were evaluated...
[Menopausal hormone therapy and cardiovascular disease]Nanette K Wenger
Emory University School of Medicine, Grady Memorial Hospital, Emory Heart and Vascular Center, Atlanta, Georgia, USA
Rev Esp Cardiol 59:1058-69. 2006....
Angiographic and clinical outcomes of bivalirudin versus heparin in patients with acute coronary syndrome undergoing percutaneous coronary interventionFadi Matar
Cardioquest Research Laboratories, Florida Cardiovascular Institute, Tampa, USA
Can J Cardiol 22:1139-45. 2006..Bivalirudin, a direct thrombin inhibitor, has recently been shown to be an effective alternative for patients undergoing elective PCI...
Relation of C-reactive protein level and long-term risk of death or myocardial infarction following percutaneous coronary intervention with a sirolimus-eluting stentJuhana Karha
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Cardiol 98:616-8. 2006..This finding was present in the BMS and SES groups and highlights the need for aggressive risk-factor modification after PCI...
Outcome after coronary artery bypass graft surgery, coronary angioplasty and stentingHenry Volzke
Institute of Epidemiology and Social Medicine, Ernst Moritz Arndt University, Walther Rathenau Str 48, D 17487 Greifswald, Germany
Int J Cardiol 116:46-52. 2007..We undertook this prospective observational study to investigate the long-term prognosis after balloon angioplasty (PTCA), coronary stenting (CS) and coronary artery bypass grafting (CABG)...
[What influences the rate of complications during phase II. residential cardiac rehabilitation after coronary events?]Attila Simon
Allami Szívkórház, Balatonfured
Orv Hetil 147:687-92. 2006....
Bridge to operation with the GPIIb/IIIa inhibitor abciximab in high-risk coronary patientsF Schoenhoff
Department of Thoracic and Cardiovascular Surgery, University of Mainz, Mainz, Germany
Thorac Cardiovasc Surg 54:150-6. 2006..7 % vs. 6.1 %). CONCLUSION: The GPIIb/IIIa inhibitor abciximab can be safely used as a bridge to operation and results in a better hemodynamic outcome in high-risk coronary patients while reducing the incidence of major ischemic events...
N-terminal probrain natriuretic peptide and C-reactive protein in stable coronary heart diseaseGjin Ndrepepa
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Munich, Germany
Am J Med 119:355.e1-8. 2006..The aim of the study was to investigate whether combined use of NT-proBNP and CRP improves risk stratification in these patients...
Coronary heart disease in women: update 2008N K Wenger
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Clin Pharmacol Ther 83:37-51. 2008..Although these women have more comorbidity and risk factors, other issues including biological differences, treatment differences, and psychosocial factors require management strategies tailored to the unique needs of women...
[From risk factors to symptomatic coronary artery disease. Update cardiology 2001/2002--part I]Roland Fries
Medizinische Klinik und Poliklinik, Innere Medizin III, Kardiologie Angiologie, Universitatskliniken des Saarlandes, Hamburg Saar
Med Klin (Munich) 98:218-25. 2003....
Use of a simple clinical score to predict prognosis of patients with normal or mildly abnormal resting electrocardiographic findings undergoing evaluation for coronary artery diseaseKheng-Thye Ho
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 77:515-21. 2002..CONCLUSION: In symptomatic patients with known or suspected CAD and normal or mildly abnormal resting ECG findings, this simple, easily computed clinical score is a useful and valid tool to help determine prognosis...
Coronary rotational atherectomy in current practice: acute and mid-term results in high- and low-volume centersPaolo Rubartelli
Division of Cardiology, Ospedale San Martino, Genoa, Italy
Catheter Cardiovasc Interv 61:463-71. 2004..Center RA volume was not associated with in-hospital or 9-month outcome. We conclude that RA, even when used sporadically in selected complex lesions, can provide good immediate and mid-term results...
Subclavian coronary steal syndrome: an obligatory common fate between subclavian artery, internal mammary graft and coronary circulationDan Elian
Heart Institute, Sheba Medical Center, Tel Hashomer 52621, Israel
Cardiology 97:175-9. 2002..The subclavian coronary steal syndrome, although rare, is a severe condition readily treated by angioplasty and stenting...
Prevalence of coronary occlusion and outcome of an immediate invasive strategy in suspected acute myocardial infarction with and without ST-segment elevationYutaka Koyama
Department of Cardiology, Royal North Shore Hospital, St Leonards, New South Wales, Australia
Am J Cardiol 90:579-84. 2002..5% died at 6 months. The prevalence of coronary flow limitation in clinically suspected NSTEMI is almost as high as in suspected STEMI. Short- and long-term outcomes of an immediate invasive strategy are similar for the 2 conditions...
Sequential use of internal thoracic artery in myocardial revascularization: mid- and long-term results of 430 patients(1)C Bakay
Florance Nightingale Hospital, Caglayan/Istanbul, Turkey
Cardiovasc Surg 10:481-8. 2002....
Clinical impact of abciximab on long-term outcome after complex coronary angioplastyJasper S Wijpkema
Department of Cardiology, University Hospital Groningen, Groningen, The Netherlands
Catheter Cardiovasc Interv 60:339-43. 2003..76). The use of abciximab equalizes the difference in outcome between simple and complex lesions. Therefore, abciximab should be advocated especially in unstable and complex percutaneous coronary interventions...
[Percutaneous transluminal coronary angioplasty in 1980-85 and 1995-96: more frequent multivessel disease, fewer reoperations and no change in mortality 1 and 5 years postoperatively]R T van Domburg
Erasmus Medisch Centrum, Thoraxcentrum, Dr Molewaterplein 40, 3015 GD Rotterdam
Ned Tijdschr Geneeskd 146:2196-200. 2002..To describe the characteristics of patients undergoing coronary angioplasty (PTCA) over the past 20 years and the outcome after 1 and 5 years...
National economic impact of tirofiban for unstable angina and myocardial infarction without ST elevation; example from the United KingdomAmeet Bakhai
Clinical Trials and Evaluation Unit, Royal Brompton and Harefield NHS Trust, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
Int J Cardiol 91:163-72. 2003..Treatments such as glycoprotein IIb/IIIa antagonists like tirofiban reduce the risk of complications but the cost impact of these agents including cost offsets of avoiding complications are needed particularly in Europe...
Usefulness of gamma intracoronary radiation for totally occluded in-stent restenotic coronary narrowingArvind K Sharma
Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
Am J Cardiol 91:595-7. 2003
Fractional flow reserve predicts major adverse cardiac events after coronary stent implantationJohannes Rieber
Dept. of Cardiology, Medizinische Klinik-Innenstadt, University of Munich, Ziemssenstr. 1 80336 Munich, Germany
Z Kardiol 91:132-6. 2002..Further studies have to investigate whether outcome after stenting might be improved by guiding the procedure with a pressure guide wire...
Research Grants
- The Coronary Screening for Kidney Transplantation (COST) StudyBertram Kasiske; Fiscal Year: 2007..Candidates who are found to have significant coronary disease then undergo preemptive angioplasty or coronary artery bypass grafting to prevent posttransplant MACE...
- RESCUE: Randomized Evaluation of Patients with Stable Angina Comparing UtilizatioArthur E Stillman; Fiscal Year: 2010..effectiveness of "aggressive medical management and percutaneous coronary interventions in treating stable coronary disease for patients of different ages and with different comorbidities...
- CORONARY DISEASE MORBIDITY AND MORTALITY IN A POPULATIONVeronique L Roger; Fiscal Year: 2010..It will determine the importance of novel biomarkers to predict the risk of adverse events in clinical practice. ..
- HIGH DENSITY LIPOPROTEIN SUBSPECIES AND CORONARY DISEASEBela Asztalos; Fiscal Year: 2003..The investigators state that these studies should provide better understanding about the diagnosis and treatment of HDL deficiency for the prevention of CHD. ..
- NEUROLOGICAL AND COGNITIVE OUTCOMES FOLLOWING CABGGUY MC KHANN; Fiscal Year: 2003..This procedure, although extraordinarily successful in relieving the symptoms of coronary disease, is also associated with a variety of neurologic problems, ranging from stroke to cognitive changes and ..
- 3D CORONARY RECONSTRUCTION AND MULTIMODALITY FUSIONShiuh Yung Chen; Fiscal Year: 2003..Specifically, the spatial 3-D geometry of coronary arteries and the morphology of coronary disease will be generated from respective routine angiograms and IVUS cross-sectional images to facilitate diagnostic ..
- Cell Therapy for Improving Cardiac FunctionDouglas Vaughan; Fiscal Year: 2007..A majority of patients with HF have poor left ventricular function, with 60-70% due to chronic ischemic coronary disease. The remainder of patients experience HF due to a variety of other causes, including idiopathic and viral ..
- Role of Hydrogen Peroxide in the Mechanism of Flow-Induced Dilation of the Human David D Gutterman; Fiscal Year: 2010..Our recent data indicate that flow-mediated dilation (FMD) occurs in coronary arterioles from patients with coronary disease but operates through a novel mechanism involving endothelial production of reactive oxygen species (ROS) ..
- Transcriptional Repression of PPARgamma-2 by Glucocorticoid-Induced Leucine ZippeXing Ming Shi; Fiscal Year: 2010..Since excess belly fat increases the risks of coronary disease and causes insulin resistance, both of which are major public health threats, understanding how PPAR(2 ..
- Transcriptional Repression of PPARgamma-2 by Glucocorticoid-Induced Leucine ZippeXingming Shi; Fiscal Year: 2009..Since excess belly fat increases the risks of coronary disease and causes insulin resistance, both of which are major public health threats, understanding how PPAR(2 ..
- Transcriptional Repression of PPARgamma-2 by Glucocorticoid-Induced Leucine ZippeXing Ming Shi; Fiscal Year: 2010..Since excess belly fat increases the risks of coronary disease and causes insulin resistance, both of which are major public health threats, understanding how PPAR(2 ..
- In Vivo Measurement of Myocardial Oxygen ConsumptionBRIGITTE PONCELET; Fiscal Year: 2004..of the heart to convert oxygen into work is found in various forms of ventricular dysfunction unrelated to coronary disease (hypertrophy, cardiomyopathy)...
- Mitral Regurgitation, Heart Failure and Coronary Disease: Benefits to MV Repair?Robert Michler; Fiscal Year: 2007..Follow up at 1, 3, 6, and 12 months for the first year and at 6 month intervals thereafter, will evaluate endpoints. A Clinical Research Skills Development Core submission will accompany this proposal. (End of Abstract) ..
- Retinal Vascular Changes in Type 1 Diabetic African-AmericansMonique Roy; Fiscal Year: 2007..a potentially useful clinical prognosticator of progression of DR and incidence of CVD (hypertension, coronary disease, stroke, and lower extremity amputation)...
- IVUS Detection of Rupture Prone PlaquesMarvin M Doyley; Fiscal Year: 2009..Coronary angiography, the "gold standard" employed to assess the severity of coronary disease in symptomatic patients, reveals only the degree of luminal narrowing, and fails to visualize the arterial ..
- ANXIETY & VAGAL CONTROL OF THE HEART IN CORONARY DISEASELana Watkins; Fiscal Year: 2002..abstract_text> ..
- Flow-Mediated Dilation of Human Coronary ArteriolesDavid Gutterman; Fiscal Year: 2007..our laboratory indicate that flow-mediated dilation (FMD) occurs in coronary arterioles from patients with coronary disease however it operates through a novel mechanism involving endothelial production of reactive oxygen species (..
- Flow-Mediated Dilation of Human Coronary ArteriolesDavid D Gutterman; Fiscal Year: 2010..our laboratory indicate that flow-mediated dilation (FMD) occurs in coronary arterioles from patients with coronary disease however it operates through a novel mechanism involving endothelial production of reactive oxygen species (..
- Flow-Mediated Dilation of Human Coronary ArteriolesDavid Gutterman; Fiscal Year: 2009..our laboratory indicate that flow-mediated dilation (FMD) occurs in coronary arterioles from patients with coronary disease however it operates through a novel mechanism involving endothelial production of reactive oxygen species (..
