Genomes and Genes
transposition of great vessels
Summary: A congenital cardiovascular malformation in which the aorta arises entirely from the right ventricle and the pulmonary artery from the left ventricle, so that the venous return from the peripheral circulation is recirculated by the right ventricle via the aorta to the systemic circulation without being oxygenated in the lungs.
Publications178 found, 100 shown here
- Risk factors for neo-aortic root enlargement and aortic regurgitation following arterial switch operationC J McMahon
Lillie Frank Abercrombie Division of Pediatric Cardiology, Texas Children s Hospital and Baylor College of Medicine, Houston, TX 77030, USA
Pediatr Cardiol 25:329-35. 2004..Surgical intervention for AR was rare (2%), however, serial surveillance of such patients is vital to monitor for neo-aortic root enlargement and potential aortic valve dysfunction...
- Establishing right ventricle-pulmonary artery continuity by autologous tissue: an alternative approach for prosthetic conduit repairYukihisa Isomatsu
Department of Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women s Medical University, Japan
Ann Thorac Surg 78:173-80. 2004..This study was undertaken to compare long-term results of the use of equine pericardial conduits, autologous pericardial conduits, and direct anastomosis repair...
- Long-term outcome in congenitally corrected transposition of the great arteries: a multi-institutional studyT P Graham
Vanderbilt University Medical Center, Nashville, Tennessee 37232 2572, USA
J Am Coll Cardiol 36:255-61. 2000..The purpose of this study was to determine long-term outcome in adults with congenitally corrected transposition of the great arteries (CCTGA), with particular emphasis on systemic ventricular dysfunction and congestive heart failure (CHF)...
- Atrioventricular and ventriculoarterial discordance (congenitally corrected transposition of the great arteries): echocardiographic features, associations, and outcome in 34 fetusesG Sharland
Guy s and St Thomas Foundation Trust, London, UK
Heart 91:1453-8. 2005..To identify fetal echocardiographic features, associations, and outcome of atrioventricular and ventriculoarterial discordance...
- Transposition of the great arteriesCarole A Warnes
Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Circulation 114:2699-709. 2006..All patients should be seen periodically in a center where expertise in the clinical evaluation, imaging, and hemodynamic assessment of adult congenital heart disease is available...
- Complete transposition of the great arteries: patterns of congenital heart disease in familial precurrenceM C Digilio
Departments of Medical Genetics and Pediatric Cardiology, , Rome
Circulation 104:2809-14. 2001....
- Right ventricular dysfunction in congenitally corrected transposition of the great arteriesT S Hornung
Adolph Basser Cardiac Institute, Department of Nuclear Medicine, Royal Alexandra Hospital for Children, Sydney, Australia
Am J Cardiol 84:1116-9, A10. 1999..6 +/- 2.3 of a total of 12 segments; the extent of the resting perfusion defects correlated inversely with the RV ejection fraction...
- Population-based study of l-transposition of the great arteries: possible associations with environmental factorsKaren S Kuehl
Department of Cardiology, Children s National Medical Center, George Washington University School of Medicine, Washington, DC 20010, USA
Birth Defects Res A Clin Mol Teratol 67:162-7. 2003..L-transposition of the great arteries (l-tga) is an uncommon congenital cardiovascular malformation that occurs from abnormal looping of the primitive cardiac tube. Little is known about risk factors for the development of l-tga...
- [Transposition of great arteries. Understanding its pathogenesis]Bruno Marino
Cattedra di Cardiologia Pediatrica Istituto di Pediatria Università degli Studi La Sapienza Viale Regina Elena, 324 00161 Roma
Ital Heart J Suppl 3:154-60. 2002..The mystery is still present but perhaps some gleams of light are appearing...
- Outcome of 121 patients with congenitally corrected transposition of the great arteriesJ M Rutledge
Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, TX 77030, USA
Pediatr Cardiol 23:137-45. 2002..We support a move toward an alternative surgical approach (double switch procedure) in carefully selected patients...
- Catheter management of occluded superior baffle after atrial switch procedures for transposition of great vesselsMakram R Ebeid
Department of Pediatrics Cardiology, The University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
Am J Cardiol 95:782-6. 2005..Additionally, we report the regression of multiple systemic-to-pulmonary venous fistulas that developed as a result of the occluded baffle...
- Intermediate results of the anatomic repair for congenitally corrected transpositionMichel N Ilbawi
University of Illinois at Chicago, The Heart Institute for Children, Hope Children's Hospital, Oak Lawn, Illinois 60453, USA
Ann Thorac Surg 73:594-9; discussion 599-600. 2002..6%), and ejection fraction was 49% to 70% (mean, 60.8%+/-7.9%). CONCLUSIONS: The double switch operation can be performed safely with minimal intermediate and long-term complications...
- CFC1 mutations in patients with transposition of the great arteries and double-outlet right ventricleElizabeth Goldmuntz
Division of Cardiology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Am J Hum Genet 70:776-80. 2002..In addition, these results demonstrate that the molecular pathway involving CFC1 plays a critical role in normal and abnormal cardiovascular development...
- Surgical management and indication of left ventricular retraining in arterial switch for transposition of the great arteries with intact ventricular septumF Lacour-Gayet
Marie Lannelongue Hospital, Paris Sud University, 133 avenue de la Resistance, 92350 Le Plessis Robinson, Paris, France
Eur J Cardiothorac Surg 20:824-9. 2001..In cases of late referral, perinatal complications or early left ventricular (LV) dysfunction, the one stage arterial switch is contra indicated. Anatomical repair remains possible in these patients following a LV retraining...
- Early and late results of operations for defects associated with corrected transposition and other anomalies with atrioventricular discordance in a pediatric populationG Biliciler-Denktas
Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA
J Thorac Cardiovasc Surg 122:234-41. 2001..CONCLUSIONS: These results can serve as a basis for comparison with newer surgical alternatives proposed for corrected transposition of the great arteries...
- Repair of transposition of the great arteries, ventricular septal defect and left ventricular outflow tract obstructionJeong Ryul Lee
Department of Thoracic and Cardiovascular Surgery, Seoul National University Children s Hospital, Seoul National University College of Medicine, Seoul National University Medical Research Center, Jongro Gu, Seoul 110 744, South Korea
Eur J Cardiothorac Surg 25:735-41. 2004....
- Two-stage arterial switch operation: is late ever too late?Howaida O Al Qethamy
Department of Cardiac Surgery Prince Sultan Cardiac Centre Riyadh Military Hospital Riyadh, Saudi Arabia
Asian Cardiovasc Thorac Ann 10:235-9. 2002....
- Long-term outcome of surgically treated patients with corrected transposition of the great arteriesViktor Hraska
Department of Pediatric Cardiac Surgery, University Hospital Hamburg-Eppendorf, Germany
J Thorac Cardiovasc Surg 129:182-91. 2005..Alternative surgical approaches, such as the double-switch, Senning-Rastelli, or Fontan procedures, are likely to have better long-term results, especially in the highest risk groups...
- Late outcome of Senning and Mustard procedures for correction of transposition of the great arteriesL Dos
Department of General Cardiology, Hospital Materno-Infantil Vall d'Hebron, Barcelona, Spain
Heart 91:652-6. 2005..Nevertheless, better outcomes may be offered through improved diagnostic methods for right ventricular function and better management of supraventricular tachyarrhythmias...
- Missense mutations and gene interruption in PROSIT240, a novel TRAP240-like gene, in patients with congenital heart defect (transposition of the great arteries)Nadja Muncke
Institut fur Humangenetik, Universitat Heidelberg, Heidelberg, Germany
Circulation 108:2843-50. 2003..TGA represents a septation defect of the common outflow tract of the heart, manifesting around the fifth week during embryonic development. Despite its high prevalence, very little is known about the pathogenesis of this disease...
- Outcomes of definitive surgical repair for congenitally corrected transposition of the great arteries or double outlet right ventricle with discordant atrioventricular connections: risk analyses in 189 patientsToshiharu Shin'oka
Department of Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women s Medical University, Tokyo, Japan
J Thorac Cardiovasc Surg 133:1318-28, 1328.e1-4. 2007....
- Results of the double switch operation for congenitally corrected transposition of the great arteriesBrian W Duncan
Pediatric and Congenital Heart Surgery, The Children s Hospital at the Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, USA
Eur J Cardiothorac Surg 24:11-9; discussion 19-20. 2003..To determine the outcomes for a program that utilizes the double switch operation as the primary approach for congenitally corrected transposition...
- Midterm results after restoration of the morphologically left ventricle to the systemic circulation in patients with congenitally corrected transposition of the great arteriesStephen M Langley
Department of Cardiac Surgery, Diana Princess of Wales Children s Hospital, Birmingham, United Kingdom
J Thorac Cardiovasc Surg 125:1229-41. 2003..This study was undertaken to determine the outcomes of patients with congenitally corrected transposition of the great arteries after restoration of the morphologically left ventricle to the systemic circulation...
- Aortic translocation in the management of transposition of the great arteries with ventricular septal defect and pulmonary stenosis: results and follow-upVictor O Morell
Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Ann Thorac Surg 79:2089-92; discussion 2092-3. 2005..The objective in this retrospective study was to review our experience using aortic translocation and biventricular outflow tract reconstruction as an alternative surgical procedure for the management of these patients...
- Technical aspects of the Rastelli and atrial switch procedure for congenitally corrected transposition of the great arteries with ventricular septal defect and pulmonary stenosis or atresia: results of therapyWilliam J Brawn
Birmingham's Children's Hospital NHS Trust, Diana, Princess of Wales Children's Hospital, Birmingham, UK
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 6:4-8. 2003..A disadvantage is that these patients require valved conduit changes over the years...
- Sequential diagnosis of coronary arterial anatomy in congenitally corrected transposition of the great arteriesIng Sh Chiu
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Ann Thorac Surg 75:422-9; discussion 429. 2003..Precise CA anatomy is surgically needed in the current era of double switch for CCT...
- Follow-up outcomes 10 years after arterial switch operation for transposition of the great arteries: comparison of cardiological health status and health-related quality of life to those of the a normal reference populationWilfred B de Koning
Department of Paediatrics Division of Cardiology, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
Eur J Pediatr 167:995-1004. 2008..Aortic root dilatation is frequent, irrespective of the anatomical subgroup. Severe aortic regurgitation or left ventricular dilatation was not found. The unfavourable health-related quality of life deserves further attention...
- Preoperative identification of coronary arterial anatomy in complete transposition, and outcome after the arterial switch operationColin J McMahon
Section of Pediatric Cardiology, Division of Congenital Heart Surgery, LillieFrank Abercrombie Division of Pediatric Cardiology, Texas Children s Hospital, 6621 Fannin, Houston, Texas 77030, USA
Cardiol Young 12:240-7. 2002..Perceived correlation between the coronary arterial anatomy in patients with complete transposition, and the outcome of the arterial switch procedure, has made preoperative identification of their patterns standard practice...
- Association of transposition of the great arteries in infants with maternal exposures to herbicides and rodenticidesC A Loffredo
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Am J Epidemiol 153:529-36. 2001..6). No data were collected on specific chemicals or brand names. These results raise new questions about the possible epidemiologic association of TGA with some classes of pesticides and warrant new, carefully targeted investigations...
- Extending the surgical boundaries in the management of the left ventricular outflow tract obstruction in discordant ventriculo-arterial connections--a surgical and morphological studyPaula Martins
Paediatric Cardiology Department, Paediatric Hospital of Coimbra, Portugal
Cardiol Young 18:124-34. 2008..In this review, we assess all these surgical and anatomic aspects, focussing on their relative importance in clinical assessment...
- Transposition of the great arteriesPaula Martins
Serviço de Cardiologia Pediátrica, Hospital Pediátrico de Coimbra, Coimbra, Portugal
Orphanet J Rare Dis 3:27. 2008..However, the exercise performance, cognitive function and quality of life may be impaired...
- A multiple retinoic acid antagonist induces conotruncal anomalies, including transposition of the great arteries, in miceDaria Cipollone
Department of Public Health and Cell Biology, University of Rome Tor Vergata, 00173 Rome, Italy
Cardiovasc Pathol 15:194-202. 2006..CONCLUSIONS: Transposition of the great arteries can be consistently reproduced in mice by administration of a retinoic acid competitive antagonist on 7.5 dpc...
- Anatomic repair for congenitally corrected transposition of the great arteriesRajesh Sharma
Narayana Hrudayalaya Institute of Cardiac Sciences, Bangalore, India
J Thorac Cardiovasc Surg 137:404-412.e4. 2009..Anatomic repair is being actively evaluated as the preferred option for congenitally corrected transposition of the great arteries. We present our 13-year experience with this approach...
- Progressive tricuspid valve disease in patients with congenitally corrected transposition of the great arteriesL R Prieto
Department of Pediatrics, College of Physicians and Surgeons of Columbia University, New York, NY, USA
Circulation 98:997-1005. 1998..The relative importance of these factors in long-term outcome has not been evaluated...
- The morphologic left ventricle that requires training by means of pulmonary artery banding before the double-switch procedure for congenitally corrected transposition of the great arteries is at risk of late dysfunctionDavid W Quinn
Department of Cardiac Surgery, Birmingham Children s Hospital NHS Trust, Birmingham, United Kingdom
J Thorac Cardiovasc Surg 135:1137-44, 1144.e1-2. 2008....
- Neonatal death due to transposition in association with premature closure of the oval foramenMichael Ashworth
Department of Paediatric Histopathology, Great Ormond Street Hospital, London, UK
Cardiol Young 16:586-9. 2006..Premature closure of the oval foramen is rare in the setting of transposition. As far as we know, there have been only three previously reported cases...
- Detection of transposition of the great arteries in fetuses reduces neonatal morbidity and mortalityD Bonnet
Service de Cardiologie Pediatrique, Hopital Necker Enfants Malades, Paris, France
Circulation 99:916-8. 1999..Transposition of the great arteries (TGA) is a life-threatening malformation in neonates, but it is amenable to complete repair. Prenatal detection, diagnosis, and early management may modify neonatal mortality and mortality...
- Double switch for congenitally corrected transposition of the great arteriesR Sharma
Cardio Thoracic Centre, All India Institute of Medical Sciences, New Delhi
Eur J Cardiothorac Surg 15:276-81; discussion 281-2. 1999..To evaluate the early and medium term results of operations for congenitally corrected transposition of the great arteries (CCTGA) wherein the left ventricle becomes the systemic ventricle...
- Familial transposition of the great arteries caused by multiple mutations in laterality genesAlessandro De Luca
Mendel Laboratory, Casa Sollievo della Sofferenza Hospital, IRCCS, San Giovanni Rotondo, Italy
Heart 96:673-7. 2010..In general, TGA is not associated with the more common genetic disorders nor with extracardiac anomalies, whereas it can be found in individuals with lateralisation defects, heterotaxy and asplenia syndrome (right isomerism)...
- X-linked transposition of the great arteries and incomplete penetrance among males with a nonsense mutation in ZIC3A Megarbane
Unite de Genetique Medicale, Faculte de Medecine, Université Saint Joseph, Beirut
Eur J Hum Genet 8:704-8. 2000..To our knowledge, this is the first instance of incomplete penetrance in a male for a mutation in a chromosome X gene...
- Twenty-five-year experience with rastelli repair for transposition of the great arteriesC Kreutzer
Departments of Cardiology and Cardiac Surgery, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
J Thorac Cardiovasc Surg 120:211-23. 2000..Our purpose was to describe the outcome of the Rastelli repair in D -transposition of the great arteries and to determine the risk factors associated with unfavorable events...
- Congenital Heart Surgery Nomenclature and Database Project: transposition of the great arteriesJ J Jaggers
Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
Ann Thorac Surg 69:S205-35. 2000..These data can lay the foundation for comprehensive risk stratification analyses. A minimum database set is also presented which will allow for data sharing and would lend itself to basic interpretation of trends...
- Late reoperations after neonatal arterial switch operation for transposition of the great arteriesEmanuela Angeli
Department of Pediatric Cardiac Surgery, University Paris Descartes and Sick Children Hospital, Paris, France
Eur J Cardiothorac Surg 34:32-6. 2008..Left ventricular function is maintained in the vast majority of patients. Reoperation may be indicated in some patients for other reasons: mitral valve malformation, tracheo-bronchial compression or pulmonary hypertension...
- Noncardiac malformations in congenital heart disease: a retrospective analysis of 305 pediatric autopsiesSafak Gucer
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey
Turk J Pediatr 47:159-66. 2005..Proper identification and treatment of CHD early in the prenatal period will save the family from the economic and emotional burden caused by having such a child with CHD...
- Production of proinflammatory cytokines and myocardial dysfunction after arterial switch operation in neonates with transposition of the great arteriesHedwig H Hövels-Gürich
Department of Pediatric Cardiology, Institute of Biomedical Statistics, Aachen University of Technology, Pauwelsstrasse 30, D 52057 Aachen, Germany
J Thorac Cardiovasc Surg 124:811-20. 2002..The purpose of this study was to test the hypothesis that the production of proinflammatory cytokines during cardiac surgery would be associated with myocardial dysfunction after the arterial switch operation in neonates...
- Late outcome after arterial switch operation for transposition of the great arteriesJ Losay
Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France
Circulation 104:I121-6. 2001..Early and midterm results of the arterial switch operation (ASO) in transposition of the great arteries (TGA) are good, but late outcome data in large populations are still few...
- Long term outcome up to 30 years after the Mustard or Senning operation: a nationwide multicentre study in BelgiumP Moons
Centre for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
Heart 90:307-13. 2004..To assess long term outcome of patients who underwent Mustard or Senning repair for transposition of the great arteries up to 30 years earlier...
- Newborn patients exhibit an unusual pattern of interleukin 10 and interferon gamma serum levels in response to cardiac surgeryA J Alcaraz
Department of Pediatrics and Pediatric Surgery, Pediatric Intensive Care Unit, , Madrid, Spain
J Thorac Cardiovasc Surg 123:451-8. 2002..This cytokine imbalance could have potential clinical implications...
- The year in congenital heart diseaseThomas P Graham
Division of Pediatric Cardiology, Vanderbilt Children' s Hospital, Nashville, Tennessee 37232-9119, USA
J Am Coll Cardiol 50:368-77. 2007
- En bloc rotation of the truncus arteriosus--an option for anatomic repair of transposition of the great arteries, ventricular septal defect, and left ventricular outflow tract obstructionRudolf Mair
Department of Cardiac Surgery, General Hospital Linz, Austria
J Thorac Cardiovasc Surg 131:740-1. 2006
- Long-term outcomes after the atrial switch for surgical correction of transposition: a meta-analysis comparing the Mustard and Senning proceduresPaul Khairy
Boston Adult Congenital Heart Service, Brigham and Women s Hospital, USA
Cardiol Young 14:284-92. 2004..We conclude that outcomes are not uniform among patients submitted to the Mustard and Senning procedures. Knowledge of such differences may facilitate stratification of risk and follow-up...
- [Surgical management of preterm infants and low birth weight neonates with congenital heart disease]Istvan Hartyanszky
Gottsegen György Országos Kardiológiai Intézet, Gyermekszív Központ, Budapest
Orv Hetil 146:69-73. 2005..These patients are endangered because of their age as well, they require special treatment and the surgical treatment has always meant high risk, urgent interventions...
- Left-sided lesions after anatomic repair of transposition of the great arteries, ventricular septal defect, and coarctation: surgical factorsSiamak Mohammadi
Department of Pediatric Cardiac Surgery, Marie-Lannelongue Hospital, Le Plessis-Robinson, France
J Thorac Cardiovasc Surg 128:44-52. 2004..Avoidance of late recoarctation of the aorta and progressive neoaortic regurgitation requires meticulous closure of the ventricular septal defect and evenly sized reconstruction of the aorta from root to distal arch...
- Long-term predictors of aortic root dilation and aortic regurgitation after arterial switch operationMarcy L Schwartz
Department of Cardiology, Children s Hospital, 300 Longwood Avenue, Boston, Mass 02115, USA
Circulation 110:II128-32. 2004..Neo-aortic root dilation (ARD) and neo-aortic regurgitation (AR) may be progressive after arterial switch operation (ASO) for d-loop transposition of the great arteries (dTGA). We sought to identify predictors of ARD and AR after ASO...
- Early and mid-term outcome of the arterial switch operation in 114 consecutive patients : A single centre experienceC Prandstetter
Department of Peadiatric Cardiology, Children s Heart Centre Linz, Krankenhausstrasse 26 30, 4020 Linz, Austria
Clin Res Cardiol 96:723-9. 2007..The purpose of this study was to assess early and mid-term outcome after ASO in a single centre...
- Valved bovine jugular vein conduits for right ventricular outflow tract reconstruction in children: an attractive alternative to pulmonary homograftJohn W Brown
Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
Ann Thorac Surg 82:909-16. 2006..Recently a valve-containing bovine jugular vein (Contegra, Medtronic, Inc, Minneapolis, MN) was introduced for clinical trials for a variety of patients requiring RVOT reconstruction...
- Primary surgical correction of transposition of the great arteries and atrioventricular septal defect associated with left isomerismS Kikuchi
Department of Cardiovascular Surgery, Hokkaido Children s Hospital and Medical Center, Zenibako 1 10 1 Otaru, Hokkaido, 047 0261, Japan
Pediatr Cardiol 27:124-7. 2006..To the best of our knowledge, this is the first report of successful primary surgical repair of TGA and AVSD with left isomerism. Primary anatomic correction of this defect combination is feasible in patients with left isomerism...
- Serum cardiac troponin-I elevation in neonatal cardiac surgery is lesion-dependentNeeta R Saraiya
Department of Anesthesiology, Columbia University, New York, NY 10032, USA
J Cardiothorac Vasc Anesth 19:620-5. 2005..46 +/- 3.5 ng/mL). CONCLUSION: It was found that perioperative elevations in serum cTn-I in neonates with TGA and HLHS were influenced by duration of aortic cross-clamp application, CPB, and the presence of VSD...
- Postoperative prophylactic peritoneal dialysis in neonates and infants after complex congenital cardiac surgeryTijen Alkan
V.K.V. American Hospital, Department of Cardiovascular Surgery, Istanbul, Turkey
ASAIO J 52:693-7. 2006....
- Mid-term follow-up of neoaortic regurgitation after the arterial switch operation for transposition of the great arteriesHo Young Hwang
Department of Thoracic and Cardiovascular Surgery, Clinical Research Institute, Seoul National University, College of Medicine, Seoul National University Children's Hospital, 28 Yongon-dong, Jongro-gu, Seoul 110-744, South Korea
Eur J Cardiothorac Surg 29:162-7. 2006..CONCLUSIONS: Neoaortic valve regurgitation progressed after the arterial switch operation. The degree of regurgitation was more severe in patients with a size discrepancy between the aorta and the pulmonary artery preoperatively...
- Prevalence of arrhythmias and their risk factors mid- and long-term after the arterial switch operationGeorge Hayashi
Department of Pediatrics, Shimane University School of Medicine, 89 1, Enya cho, Izumo City, Shimane, 693 8501, Japan
Pediatr Cardiol 27:689-94. 2006..VSD was a risk factor for postoperative arrhythmia, especially CAVB. Approximately half of the arrhythmias developed late. Lifelong monitoring with respect to arrhythmia is needed for patients after ASO...
- Late coronary artery lesions after neonatal arterial switch operation: results of surgical coronary revascularizationOlivier Raisky
Department of Pediatric Cardiac Surgery, University Paris Descartes and Sick Children Hospital, Paris, France
Eur J Cardiothorac Surg 31:894-8. 2007..To evaluate the results of surgical revascularization in children with coronary artery lesions following neonatal arterial switch operation (ASO)...
- The optimal procedure for the great arteries and left ventricular outflow tract obstruction. An anatomical studyMark Hazekamp
Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands
Eur J Cardiothorac Surg 31:879-87. 2007..To describe the optimal surgical strategy in heart specimens with transposition of the great arteries (TGA) and left ventricular outflow tract obstruction (LVOTO)...
- Acquired coronary artery fistula after open heart surgery for congenital heart diseaseShuenn-Nan Chiu
Department of Pediatrics, National Taiwan University Hospital, School of Medicine, National Taiwan University, 7 Chung-Shan S. Rd, Taipei 100, Taiwan
Int J Cardiol 103:187-92. 2005..Although shunt flow did not increase during follow-up, the significance of acquired coronary artery fistula needs further investigation...
- Unusual and early hyperglycemia following amiodarone infusion in two infantsS V Yildirim
Division of Pediatric Cardiology, Baskent University, Faculty of Medicine, Ankara, Turkey
Pediatr Cardiol 26:715-6. 2005..We present two infants who had hyperglycemia following amiodarone infusion during the early postoperative period...
- Surgery for right ventricle to pulmonary artery conduit obstruction: risk factors for further reoperationSiamak Mohammadi
Department of Pediatric Cardiac Surgery, Marie Lannelongue Hospital, 133 ave de la Résistance, 92350 Le Plessis Robinson, France
Eur J Cardiothorac Surg 28:217-22. 2005..To identify the surgical approaches and risk factors which influence longevity of right ventricle to pulmonary artery (RV-PA) conduits following first reoperation for obstruction...
- Surgical results of arterial switch operation for Taussig-Bing anomaly: is position of the great arteries a risk factor?Mark D Rodefeld
Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
Ann Thorac Surg 83:1451-7. 2007..This study identifies the impact of the position of the great arteries and use of a staged surgical approach on the outcome after the arterial switch operation in children with Taussig-Bing anomaly...
- Surgical management of transposition with ventricular septal defect and obstruction to the left ventricular outflow tractVictor O Morell
Division of Cardiothoracic Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh, PA 15213, USA
Cardiol Young 15:102-5. 2005
- Is preoperative delineation of coronary artery pattern a prerequisite for arterial switch operation?Ghassan M Baslaim
Division of Cardiothoracic Surgery, Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
J Card Surg 21:465-70. 2006..To determine the effect of preoperative echocardiographic delineation of coronary artery pattern on the immediate postoperative result of arterial switch procedures...
- Chromosome 22q11 deletions in patients with conotruncal heart defectsA Khositseth
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
Pediatr Cardiol 26:570-3. 2005..A subgroup of patients with IAA, TA, SPVSD, and PAVSD associated with phenotypic features or abnormalities warrants evaluation for the presence of 22q11 deletions...
- State of the art of cardiac surgery in patients with congenital heart diseaseLucio Zannini
Division of Pediatric Cardiac Surgery, IRCCS Giannina Gaslini, Genoa, Italy
J Cardiovasc Med (Hagerstown) 8:3-6. 2007....
- [Arterial switch operation for transposition of the great arteries and double outlet of right ventricle with subpulmonary ventricular septum defect]Zhi-Wei Xu
Department of Thoracic and Cardiovascular Surgery, Xinhua Hospital, Shanghai Second Medical University, Shanghai 200127, China
Zhonghua Wai Ke Za Zhi 42:451-4. 2004..The procedure used in treatment on Taussig-Bing can prevent pulmonary obstruction and avoid the complication of left ventricular outflow tract obstruction caused by intraventricular repair...
- Risk factors for mortality after the Norwood procedureJ William Gaynor
Division of Cardiothoracic Surgery, The Cardiac Center at The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Suite 8527, Philadelphia, PA 19104, USA
Eur J Cardiothorac Surg 22:82-9. 2002..The current study was undertaken to evaluate our recent experience with the Norwood procedure and to evaluate potential predictors of operative and 1-year mortality...
- Arterial switch operation with a single coronary arteryAlbertus M Scheule
Department of Cardiac Surgery, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA
J Thorac Cardiovasc Surg 123:1164-72. 2002..Risk of reintervention is higher in patients having a single left ostium with the right coronary artery anterior to the aorta...
- [Double switch operation (Senning and Rastelli operation) with left atrial augumentation by in situ autologous pericardium: a case report]M Ogawa
Department of Pediatric Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
Kyobu Geka 54:1099-102. 2001..For the purpose of atrial augumentation without artificial materials, our modified Senning procedure is useful. But longer follow-up is necessary to determine whether this technique is indeed beneficial...
- Aneurysmal pericardial patch producing right ventricular inflow obstructionG B Bennink
Department of Cardiology, Wilhelmina Children's Hospital, Utrecht, The Netherlands
Ann Thorac Surg 71:1346-7. 2001..Echocardiography demonstrated aneurysmal dilation of the native pericardial patch used for VSD closure, resulting in right ventricular inflow obstruction. The pericardial patch was excised, and the VSD closed using a GoreTex patch...
- Arterial switch operation for transposition of the great arteries combined with closure of paramembranous ventricular septal defect using the Amplatzer membranous ventricular septal occluderHakan Akintuerk
Pediatric Heart Center, Justus-Liebig University, Giessen, Germany
Am J Cardiol 96:592-4. 2005..The cardiac arrest time for anatomic repair might be effectively reduced by this new approach in pediatric cardiac surgery...
- Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgeryJane W Newburger
Department of Cardiology, Children s Hospital Boston, Boston, Mass 02115, USA
J Thorac Cardiovasc Surg 135:347-54, 354.e1-4. 2008..However, worse outcomes were concentrated in patients with hematocrit values of 20% or below, and the benefits of hematocrit values higher than 25% were uncertain...
- Long-term outcomes and social independence level after arterial switch operationAkira Yamazaki
Department of Cardiovascular Surgery, Tokyo Women s Medical University, Japan
Eur J Cardiothorac Surg 33:239-43. 2008..Various issues regarding the long-term survivors of arterial switch operation (ASO) have been clarified according to the improvement of surgical mortality. We reviewed the long-term results and social independence level after ASO...
- [Arterial switch operation: late results and a future perspective]Mitsuru Aoki
Department of Cardiovascular Surgery, Chiba Children s Hospital, Chiba, Japan
Kyobu Geka 61:268-73. 2008..Risk factors for aortic regurgitation were age at operation and prior PAB. Early primary arterial switch operation may resolve these problems...
- [Long term outcome of arterial switch surgery for transposition of the great arteries: evaluation of the reconstruction of the pulmonary artery]Hiroaki Kawata
Department of Cardiovascular Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Japan
Kyobu Geka 61:303-9. 2008....
- Predictors of outcome of arterial switch operation for complex D-transpositionDanielle Gottlieb
Department of Cardiology and Cardiovascular Surgery, Children s Hospital Boston, Boston, Massachusetts, USA
Ann Thorac Surg 85:1698-702; discussion 1702-3. 2008..D-TGA with ventricular septal defect (VSD) and aortic arch obstruction (AAO) is a higher risk subgroup in which we sought risk factors for mortality and reoperation after ASO...
- [Double discordances with ventricular septal defect and pulmonary obstruction. A study of 72 cases]P Acar
, , Paris
Arch Mal Coeur Vaiss 90:625-9. 1997..Therefore, there is no place for elective surgery in this malformation: when necessary, the best option is to remain palliative as long as possible: when correction is required, an anatomical correction is the best procedure...
- Determinants of right ventricular outflow tract conduit longevity: a multinational analysisMarieke B A Niemantsverdriet
Pediatric Cardiology, Center for Congenital Abnormalities of Heart, Amsterdam Leiden, The Netherlands
Congenit Heart Dis 3:176-84. 2008..We compared two diverse surgical centers with considerable practice variation in Europe and the United States to identify modifiable risk factors that can increase conduit longevity...
- Arterial switch operation: troponin T does not predict ventilation requirementsMadan M Maddali
Departments of Anesthesia and Cardiothoracic Surgery, Royal Hospital, Seeb, Muscat, Sultanate of Oman
Asian Cardiovasc Thorac Ann 16:274-7. 2008..It was concluded that the postoperative cardiac troponin T level is not a predictor of successful extubation or prolonged artificial ventilation in this subset...
- [Double outlet left ventricle: a rare and unusual cardiopathy. Apropos of 7 new cases]M Gouton
Arch Mal Coeur Vaiss 89:553-9. 1996..The anatomical variability is due to the complex embryogenesis of the conotruncal region and explains the clinical diversity of this congenital cardiac malformation...
- [Systemic pulmonary shunts in the neonatal period. Short and medium-term results]A Chantepie
, , CHU de Tours
Arch Mal Coeur Vaiss 88:693-8. 1995..Cardiac failure occurred in 83% of group B and 22% of group A (p < 0.01). The probability of shunt efficacy was 89% at 1 year, 63% at 2 years and 45% at 3 years.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Early and long term outcome of the arterial switch operation for transposition of the great arteries: predictors and functional evaluationEdvin Prifti
G Pasquinucci Hospital, CREAS IFC CNR, Via Aurelia Sud, 54100 Massa, Italy
Eur J Cardiothorac Surg 22:864-73. 2002....
- Obliteration of a competitive forward flow from the ventricle after a bidirectional cavopulmonary shunt with an Amplatzer duct occluderCarlo B Pilla
, , Brazil
J Invasive Cardiol 15:98-101. 2003..After test occlusion, an Amplatzer duct occluder was implanted at the PA banding site with subsequent decrease in the PA pressure, resolution of the edema and extubation...
- Technical aspects of the combined arterial switch and senning operation for congenitally corrected transposition of the great arteriesEric J Devaney
Section of Cardiac Surgery, Division of Pediatric Cardiac Surgery, University of Michigan School of Medicine, Ann Arbor, MI, USA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 6:9-15. 2003..Anatomic repair by double switch technique may improve survival of patients with ccTGA by establishing the morphologic left ventricle in the systemic circulation...
- Current expectations for newborns undergoing the arterial switch operationDaniel J Dibardino
Division of Congenital Heart Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine and Texas Children's Hospital, 6621 Fannin Street, Houston, TX 77030, USA
Ann Surg 239:588-96; discussion 596-8. 2004..CONCLUSIONS: Using current methodologies, the ASO can be performed safely and with a low incidence of need for reoperation on intermediate follow-up. Recent experience indicates operative survival rates approaching 100%...
- Application of modified perfusion technique on one stage repair of interrupted aortic arch in infants: a case series and literature reviewJinping Liu
Department of Cardiopulmonary Bypass, Fuwai Hospital, CAMD and PUMS, Beijing, China
ASAIO J 53:666-9. 2007....
- Long-term results of left ventricular reconditioning and anatomic correction for systemic right ventricular dysfunction after atrial switch proceduresNancy C Poirier
Ste-Justine Hospital, Montreal, Quebec, Canada
J Thorac Cardiovasc Surg 127:975-81. 2004..It is an alternative to cardiac transplantation in selected patients, with good long-term results. The response to morphologically left ventricular reconditioning past adolescence is inconsistent...
- Functional acquired pulmonary atresia secondary to subpulmonary aneurysmal tissue: a rare form of pulmonary outflow tract obstructionGrace C Kung
Department of Pediatrics, Baylor College of Medicine, 6621 Fannin, Houston, TX, USA
J Am Soc Echocardiogr 17:284-5. 2004
- [MRI of congenital heart disease in childhood]F Weiss
Radiologisches Zentrum, Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie, Universitatsklinikum Hamburg Eppendorf
Rofo 176:191-9. 2004..The aim of this article is to impart knowledge, to mention problems and to provide guidance in the performance of cardiac MRI in patients with CHD...
- Abnormal origin of the right subclavian artery from the right pulmonary artery in a patient with D-transposition of the great vessels and left juxtaposition of the right atrial appendage: an unusual anatomical variantJackmerry Mosieri
Department of Cardiovascular Surgery, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
J Card Surg 19:41-4. 2004..We discuss the embryological basis of this anomaly and review its clinical and surgical implications...
- Transcatheter occlusion of baffle leaks following atrial switch procedures for transposition of the great vessels (d-TGV)David T Balzer
Division of Pediatric Cardiology, Department of Pediatric, St Louis Children s Hospital, Washington University School of Medicine, St Louis, Missouri, USA
Catheter Cardiovasc Interv 61:259-63. 2004....
- The effect of duration of deep hypothermic circulatory arrest in infant heart surgery on late neurodevelopment: the Boston Circulatory Arrest TrialDavid Wypij
Department of Cardiology, Children's Hospital, Harvard Medical School, Boston, 02115, USA
J Thorac Cardiovasc Surg 126:1397-403. 2003....
- Long term follow-up of left ventricular performance and size of the great arteries before and after one- and two-stage arterial switch operation of simple transpositionHans Heiner Kramer
Department of Pediatric Cardiology, Christian Albrechts University, Schwanenweg 20, 24105, Kiel, Germany
Eur J Cardiothorac Surg 24:898-905. 2003..Long-term angiographic evaluation of left ventricular performance and size of the great arteries after one-stage neonatal versus two-stage arterial switch operation (ASO) of simple transposition...
- Apico-pulmonary artery conduit repair of congenitally corrected transposition of the great arteries with ventricular septal defect and pulmonary outflow tract obstruction: a 10-year follow-upRyo Aeba
Division of Cardiovascular Surgery, Keio University, Shinjuku, Tokyo, Japan
Ann Thorac Surg 76:1383-7; discussion 1387-8. 2003....
- "Bay window" technique for the arterial switch operation of the transposition of the great arteries with complex coronary arteriesMasaaki Yamagishi
Department of Pediatric Cardiovascular Surgery, Children s Research Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan
Ann Thorac Surg 75:1769-73; discussion 1773-4. 2003..Early and midterm results of this technique are described...
- Metal Exposure and Children?s Preschool NeurodevelopmentDavid Bellinger; Fiscal Year: 2009..The effects of exposures to combinations of metals, including lead, is also a major focus. This more closely mirrors "real world" exposures, which invariably involve a mixture of compounds rather than a single compound. ..
- Cerebral Blood Flow in Single Ventricle and Normal Children Utilizing MRIMARK ALAN FOGEL; Fiscal Year: 2010..Changing the way the blood flows in these patients by surgery may alter the way we ultimately manage these patients medically and surgically. ..
- NEUROBEHAVIORAL SEQUELAE OF CARDIAC SURGERYDavid Bellinger; Fiscal Year: 2005..abstract_text> ..
- Metal Exposure and Children?s Preschool NeurodevelopmentDavid C Bellinger; Fiscal Year: 2010..The effects of exposures to combinations of metals, including lead, is also a major focus. This more closely mirrors "real world" exposures, which invariably involve a mixture of compounds rather than a single compound. ..
- Interdisciplinary Training: Neurodevelopmental Toxicology(RMI)David Bellinger; Fiscal Year: 2007..Members of the faculty currently conduct a wealth of multidisciplinary research, which will provide trainees with ready opportunities to apply their training in ongoing research projects. ..
- Effects of general vs. regional anesthesia on infant neurodevelopment and apneaMary Ellen McCann; Fiscal Year: 2010..If general and regional awake anesthesia result in neurodevelopmental outcomes that are equivalent, this would support the safety of general anesthetics as currently used. ..
- Metal Exposure and Children?s Preschool NeurodevelopmentDavid Bellinger; Fiscal Year: 2009..The effects of exposures to combinations of metals, including lead, is also a major focus. This more closely mirrors "real world" exposures, which invariably involve a mixture of compounds rather than a single compound. ..
- Cavopulmonary Assist: Circulatory Support for the Univentricular Fontan CirculatMark D Rodefeld; Fiscal Year: 2010..This will dramatically improve the healthcare of children and adults born with single ventricle heart disease. ..
- White Matter Injury in Critical Ill Newborns With Congenital Heart DiseasePatrick Sean McQuillen; Fiscal Year: 2010..Page McQuillen, Patrick S. ..
- Critical Period Plasticity Following Neonatal Brain InjuryPatrick Sean McQuillen; Fiscal Year: 2010..Understanding plasticity following injury will provide both a new outcome measure and a model to guide therapy for recovering brain function. ..
- Iron and AtherosclerosisSubha V Raman; Fiscal Year: 2010..This research tests the theory that monthly loss of iron through menses is protective against atherosclerosis, which could lead to an entirely new approach to preventing and treating heart and vascular disease in both men and women. ..
- The Genetic Etiology of Left-Sided Cardiac DefectsElizabeth Goldmuntz; Fiscal Year: 2007..In addition, these investigations will lead to future studies that assess the relationship of genotype to clinical outcome, and allow us to improve upon our clinical management accordingly. ..
- Bridge to neonatal Fontan repair of single ventricleMark Rodefeld; Fiscal Year: 2006..abstract_text> ..
- Selective subplate vulnerability and cortical plasticityPatrick McQuillen; Fiscal Year: 2007..Finally, we hypothesize that treatments that protect sub-plate neurons in vitro will also prevent sub-plate neuron cell death following early hypoxia ischemia. ..
- Cerebrovascular Physiology of Infants with CHDDaniel Licht; Fiscal Year: 2007..DOT is complimentary to MRI in that it offers excellent temporal resolution and can be applied at the point of care. Furthermore, DOT offers concurrent analysis of metabolic rate while sacrificing only mild anatomic resolution. ..
- The Genetic Etiology of Conotruncal Cardiac DefectsElizabeth Goldmuntz; Fiscal Year: 2007..With this data, the impact of genotype on clinical outcome can be assessed and improved management strategies devised for the future. ..
- APOE Genotype and Sequelae of Infant Cardiac SurgeryJames Gaynor; Fiscal Year: 2007..We propose to evaluate this cohort at 4 years of age to test the hypothesis that APOE genotype predicts cognitive impairment, impaired attention and executive function, as well as impairment of fine motor and visual-motor skills. ..
- Early Neurobiologic Regulation in Infants with Congenital Heart DefectsTondi Harrison; Fiscal Year: 2007..This knowledge will be used to develop interventions to assist mothers in establishment of patterns of caregiving supportive of their infant's development. ..
- Neurofibromin, Ras & NFAT in Cardiovascular DevelopmentFRAZ ISMAT; Fiscal Year: 2007..Together this training program will prepare me for independent investigation, lead to a better understanding of cardiovascular abnormalities in neurofibromatosis, and address fundamental issues of cardiovascular development. ..
- Iron and AtherosclerosisSubha Raman; Fiscal Year: 2006..Subgroup analyses will include comparison of the presence of iron symptomatic versus asymptomatic patients and women versus age-matched men. ..
- SUBPLATE NEURONS AND EARLY HYPOXIC ISCHEMIC BRAIN INJURYPatrick McQuillen; Fiscal Year: 2002....