Genomes and Genes
cardiovascular pregnancy complications
Summary: The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.
Publications210 found, 100 shown here
- Factor analysis, including antihypertensive medication, of the outcome of pregnancy in pregnancy-associated hypertensionM Hussein
Department of Nephrology, Dialysis and Hypertension, Al Hada Armed Forces Hospital, Taif, Saudi Arabia
Kidney Blood Press Res 24:124-8. 2001..This was not seen in the patients using nifedipine and labetalol. CONCLUSIONS: The results suggest that in multiparas, intravenous hydralazine is possibly associated with more fetal distress when compared to primiparas...
- Summary of the NHLBI Working Group on Research on Hypertension During PregnancyJames M Roberts
Department of Obstetrics, Gynecology and Reproductive Sciences, Graduate School of Public Health, University of Pittsburgh, and Magee Womens Research Institute, Pittsburgh, PA, USA
Hypertension 41:437-45. 2003..Recommendations to increase participation in this research are also presented...
- Venous thromboembolism in pregnancy and the puerperium: incidence and additional risk factors from a London perinatal databaseE L Simpson
Postgraduate Medical School, Guildford, Surrey, UK
BJOG 108:56-60. 2001..Antenatally multiple birth is an important risk factor. Postnatally women who have had a caesarean section, premature delivery or history of cardiac disease should be assessed carefully for venous thromboembolism...
- Pregnancy-related mortality due to cardiomyopathy: United States, 1991-1997Sara J Whitehead
Epidemic Intelligence Service, Epidemiology Program Office, National Center for Chronic Diseases Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Obstet Gynecol 102:1326-31. 2003....
- Clinical practice. Valvular heart disease in pregnancySharon C Reimold
University of Texas Southwestern Medical Center, Dallas, USA
N Engl J Med 349:52-9. 2003
- Cardiac risk in pregnant women with rheumatic mitral stenosisCandice K Silversides
Pregnancy and Heart Disease Research Program, Mount Sinai and Toronto General Hospitals, University of Toronto, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4
Am J Cardiol 91:1382-5. 2003
- Prospective multicenter study of pregnancy outcomes in women with heart diseaseS C Siu
University of Toronto, Toronto, Ontario, Canada
Circulation 104:515-21. 2001..The maternal and neonatal risks associated with pregnancy in women with heart disease receiving comprehensive prenatal care have not been well defined...
- Impact of pregnancy-related heart failure on humoral immunity: clinical relevance of G3-subclass immunoglobulins in peripartum cardiomyopathyRahat S Warraich
Department of Cardiothoracic Surgery, National Heart and Lung Institute, Imperial College School of Medicine, Royal Brompton and Harefield Trust, Harefield Hospital, Middlesex, England, UK
Am Heart J 150:263-9. 2005..Therefore, given that progressive gestation is associated with immunologic incompetence, we sought to study the relative impact of pregnancy-related onset of HF on humoral immunity...
- Valvular heart disease and pregnancy: part II: prosthetic valvesUri Elkayam
Heart Failure Program, Division of Cardiovascular Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
J Am Coll Cardiol 46:403-10. 2005....
- Improved outcomes in peripartum cardiomyopathy with contemporaryAnkie M Amos
Division of Cardiology, Duke University Medical Center, Durham, NC, USA
Am Heart J 152:509-13. 2006..These studies were small and predated current advances in heart failure treatment. We sought to determine the outcomes of women with PPCM in the contemporary era and to determine predictors of poor outcome...
- High prevalence of viral genomes and inflammation in peripartum cardiomyopathyBurkhard D Bültmann
Institute of Pathology, University Hospital of Tubingen, Germany
Am J Obstet Gynecol 193:363-5. 2005..7%) that were associated immunohistologically with interstitial inflammation. These findings indicate a high prevalence of virus-associated inflammatory changes in peripartum cardiomyopathy...
- Staged therapeutic approach in spontaneous coronary dissectionSiamak Aliyary
Department of Cardiology, Medisch Spectrum Twente, Enschede, The Netherlands
Ann Thorac Surg 83:1879-81. 2007..While she was on aortic balloon counterpulsation the patient underwent a cesarean section and gave birth to a healthy child. Subsequently she successfully underwent off-pump coronary artery bypass surgery...
- Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based studyJohn A Heit
Mayo Clinic, Rochester, Minnesota 55905, USA
Ann Intern Med 143:697-706. 2005..The risk for venous thromboembolism during pregnancy or postpartum is uncertain...
- Coronary artery dissection during pregnancy and the postpartum period: two case reports and review of literatureA K Koul
Division of Cardiology, Maimonides Medical Center, Brooklyn, New York 11219, USA
Catheter Cardiovasc Interv 52:88-94. 2001..Diagnostic and therapeutic considerations of this unique clinical entity are discussed and reviewed...
- Peripartum cardiomyopathy: National Heart, Lung, and Blood Institute and Office of Rare Diseases (National Institutes of Health) workshop recommendations and reviewG D Pearson
Division of Heart and Vascular Diseases, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 7940, USA
JAMA 283:1183-8. 2000....
- Different anesthesiological management in two high risk pregnant women with heart failure undergoing emergency cesarean sectionA Zangrillo
Department of Anesthesiology, Vita Salute University of Milan, IRCCS San Raffaele Hospital, 20132 Milan, Italy
Minerva Anestesiol 71:227-36. 2005..Selection of the anesthetic technique in obstetrics is the most challenging issue for the anesthesiologist: extensive knowledge of the pathophysiology of heart disease is required for an optimal choice...
- Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacyIan A Greer
Department of Obstetrics and Gynaecology, University of Glasgow, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow, G31 2ER, United Kingdom
Blood 106:401-7. 2005..01%-0.20%) of pregnancies. Overall, live births were reported in 94.7% of pregnancies, including 85.4% in those receiving LMWH for recurrent pregnancy loss. LMWH is both safe and effective to prevent or treat VTE in pregnancy...
- Labour analgesia guided by echocardiography in a parturient with primary dilated cardiomyopathyToshiyuki Okutomi
Department of Anesthesiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
Can J Anaesth 52:622-5. 2005..To evaluate the effects of intrathecal analgesics on cardiac function during labour analgesia using echocardiography in a parturient with idiopathic dilated cardiomyopathy (DCM)...
- Brief review: hypertension in pregnancy : a manifestation of the insulin resistance syndrome?C G Solomon
Division of Women s Health, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Hypertension 37:232-9. 2001....
- Calcium supplementation during pregnancy for preventing hypertensive disorders and related problemsG J Hofmeyr
University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, Frere and Cecilia Makiwane Hospitals, Private Bag X 9047, East London, Eastern Cape, South Africa 5200
Cochrane Database Syst Rev 3:CD001059. 2006..Pre-eclampsia and eclampsia are common causes of serious morbidity and death. Calcium supplementation may reduce the risk of pre-eclampsia through a number of mechanisms, and may help to prevent preterm labour...
- Thrombosis during pregnancy and the postpartum periodAndra H James
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710 and Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Obstet Gynecol 193:216-9. 2005..To describe the circumstances surrounding deep vein thrombosis among pregnant or postpartum patients enrolled in a large multicenter registry...
- Peripartum cardiomyopathyAngela Ro
Department of Medicine, St Vincent s Medical Center, New York, NY 10595, USA
Cardiol Rev 14:35-42. 2006..This article attempts to provide an updated, comprehensive review about PPCM and draw attention to areas in need of further research...
- A modified definition for peripartum cardiomyopathy and prognosis based on echocardiographyJ U Hibbard
Department of Obstetrics and Gynecology, University of Chicago, Pritzker School of Medicine, Illinois 60637, USA
Obstet Gynecol 94:311-6. 1999..The test reproduces hemodynamic stress akin to pregnancy, and the data might be useful when counseling women on future childbearing. Women who respond with reduced cardiac reserve might be advised to avoid pregnancy...
- Pregnancy-associated cardiomyopathy: clinical characteristics and a comparison between early and late presentationUri Elkayam
Heart Failure Program, Division of Cardiovascular Medicine, and Department of Obstetrics and Gynecology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
Circulation 111:2050-5. 2005..Cardiomyopathy associated with pregnancy was first described more than half a century ago. However, because of its rare occurrence and geographical differences, the clinical profile of this condition has remained incompletely defined...
- Prosthetic heart valves and pregnancyLynne Hung
Griffith Center, Division of Cardiovascular Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
Circulation 107:1240-6. 2003
- Pre-eclampsia and the hypertensive disorders of pregnancyLelia Duley
Resource Centre for Randomised Trials, Institute of Health Sciences, Headington, Oxford, UK
Br Med Bull 67:161-76. 2003..Magnesium sulphate more than halves the risk of eclampsia (RR 0.41; 95% CI 0.29, 0.58) and probably reduces the risk of maternal death (RR 0.54; 95% CI 0.26, 1.10). It is also the drug of choice for treatment of eclampsia...
- Management of grown up congenital heart diseaseJohn Deanfield
GUCH Unit, The Heart Hospital, London
Eur Heart J 24:1035-84. 2003
- Diagnosis and management of gestational hypertension and preeclampsiaBaha M Sibai
Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0526, USA
Obstet Gynecol 102:181-92. 2003..There is also a need to conduct a randomized trial to determine the benefits and risks of magnesium sulfate during labor and postpartum in women with mild preeclampsia...
- Pregnancy in patients with heart disease: experience with 1,000 casesWalkiria Samuel Avila
Heart Institute InCor University of São Paulo Medical School Brazil and Department of Obstetrics of the Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil
Clin Cardiol 26:135-42. 2003..Previously, the high maternal mortality in cardiac patients who became pregnant prompted the assertion: Women with an abnormal heart should not become pregnant. This long-standing notion needs to be revised today...
- Risks and pregnancy outcome in women with prosthetic mechanical heart valve replacementKazuya Kawamata
Department of Perinatology, National Cardiovascular Center, Suita, Japan
Circ J 71:211-3. 2007..In Japan, however, the risks and pregnancy outcomes in women with prosthetic mechanical heart valve replacement remain to be elucidated...
- Low molecular weight heparin treatment in pregnant women with a mechanical heart valve prosthesisJae Hoon Lee
Department of Thoracic and Cardiovascular Surgery, Dongsan Medical Center, Keimyung University School of Medicine, 194 Dongsan dong, Joong Gu, Daegu, Korea
J Korean Med Sci 22:258-61. 2007..Regarding the efficacy and safety of antithrombotic treatment in pregnant women with prosthetic heart valves, nadroparin treatment during the first trimester is an acceptable regimen and produces better results than coumarin derivatives...
- Prognostic value of placental ultrasound in pregnancies complicated by absent end-diastolic flow velocity in the umbilical arteriesS Viero
Department of Laboratory Medicine and Pathobiology, Mount Sinai Hospital, University of Toronto, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5
Placenta 25:735-41. 2004..Ultrasound examination of the placenta and its maternal blood supply may contribute to the perinatal management of these pregnancies...
- Placental ischemia and cardiovascular dysfunction in preeclampsia and beyond: making the connectionsJeffrey S Gilbert
Department of Physiology and Pharmacology, University of Minnesota Medical School Duluth and Duluth Medical Research Institute, Duluth, MN 55812, USA
Expert Rev Cardiovasc Ther 6:1367-77. 2008..However, the importance of the various endothelial and humoral factors that mediate these changes during PE remain to be elucidated...
- Peripartum cardiomyopathyKaren Sliwa
Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, P O Bertsham 2013, Johannesburg, South Africa
Lancet 368:687-93. 2006....
- Acute myocardial infarction associated with pregnancyArie Roth
Department of Cardiology Tel Aviv Sourasky Medical Center, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel
J Am Coll Cardiol 52:171-80. 2008....
- Maternal and fetal outcomes of subsequent pregnancies in women with peripartum cardiomyopathyU Elkayam
Department of Medicine, University of Southern California School of Medicine, Los Angeles 90033, USA
N Engl J Med 344:1567-71. 2001..Peripartum cardiomyopathy is a rare and sometimes fatal form of heart failure. Little is known about the outcomes of subsequent pregnancies in women who have had the disorder...
- ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A population-based, nested case-control studyT B Larsen
Department of Clinical Biochemistry and Genetics, Odense University Hospital, Sdr Boulevard 29, DK 5000 Odense, Denmark
J Thromb Haemost 3:300-4. 2005..To examine possible associations of ABO blood types with the risk of venous thromboembolism (VTE) in pregnancy and the puerperium...
- Maternal deaths due to hypertensive disorders in pregnancy: Saving Mothers report 2002-2004J Moodley
Women s Health and HIV Research Group, Nelson R Mandela School of Medicine, Durban
Cardiovasc J Afr 18:358-61. 2007....
- Five-year prospective study of the incidence and prognosis of peripartum cardiomyopathy at a single institutionJames D Fett
Department of Adult Medicine, Hopital Albert Schweitzer, Deschapelles, Haiti
Mayo Clin Proc 80:1602-6. 2005..To determine the incidence and prognosis of peripartum cardiomyopathy (PPCM) in rural Haiti...
- Pregnancy complicated by heart disease: a review of Canadian experienceM Sermer
Department of Obstetrics and Gynaecology, Toronto General Hospital, Toronto, Canada
J Obstet Gynaecol 23:540-4. 2003..Factors that place the mother and the neonate at risk can be identified before pregnancy. This allows informed counselling and development of a patient-specific management plan...
- Inherited thrombophilia and gestational vascular complicationsMichael J Kupferminc
Maternal Fetal Medicine Unit, Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Israel
Semin Thromb Hemost 29:185-94. 2003..However, controlled clinical trials are still necessary to allow the development of better clinical standards...
- Severe cardiac disease in pregnancy, part II: impact of congenital and acquired cardiac diseases during pregnancyWalther N K A van Mook
Department of Intensive Care and Internal Medicine, University Hospital Maastricht, Maastricht, Netherlands
Curr Opin Crit Care 11:435-48. 2005..Part II of this review gives an overview of the different maternal cardiac problems during pregnancy and their management, and developments over recent years...
- Recognition and management of maternal cardiac disease in pregnancyP Ray
Department of Anaesthesia, St Michaels Hospital, Bristol and Department of Cardiac Surgery, Bristol Royal Infirmary, Bristol BS2 8HW, UK
Br J Anaesth 93:428-39. 2004..The presence of adequate systems for early detection, appropriate referral to specialist centres, and timely delivery with multidisciplinary support can minimize the serious consequences of poorly controlled heart disease in pregnancy...
- Successful use of levosimendan in a patient with peripartum cardiomyopathySidney Benlolo
Department of Anesthesiology and Critical Care Medicine, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Institut Fédératif de Recherche 06, Paris, France
Anesth Analg 98:822-4, table of contents. 2004..We determined that she met current diagnostic criteria for peripartum cardiomyopathy, and we successfully treated her with levosimendan, a calcium-sensitizing drug with additional vasodilation properties...
- Is peripartum cardiomyopathy an organ-specific autoimmune disease?J Bruce Sundstrom
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Autoimmun Rev 1:73-7. 2002..g. expression of PD-L1 on cardiac tissues and the role of regulatory T cells, may help to elucidate the autoimmune mechanisms of PPCM...
- Peripartum cardiomyopathy: inflammatory markers as predictors of outcome in 100 prospectively studied patientsKaren Sliwa
Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, PO Bertsham 2013, Johannesburg, South Africa
Eur Heart J 27:441-6. 2006..We evaluated the prognostic role of multiple inflammatory markers in the plasma of a large cohort of African patients with PPCM...
- Labor analgesia for the parturient with cardiac disease: what does an obstetrician need to know?Krzysztof M Kuczkowski
Department of Anesthesiology, University of California, San Diego, California, USA
Acta Obstet Gynecol Scand 83:223-33. 2004..This article will review the current guidelines and standards pertinent to management of obstetric analgesia and anesthesia in parturients with cardiac disease...
- Pregnancy in heart diseaseS A Thorne
The Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK
Heart 90:450-6. 2004
- Combined spinal-epidural anesthesia for Cesarean section in a patient with peripartum dilated cardiomyopathyR Shnaider
Department of Anesthesiology University of Texas Medical School at Houston, Houston, Texas 77030, USA
Can J Anaesth 48:681-3. 2001..The patient's perioperative course was uneventful. CONCLUSION: In patients suffering from peripartum cardiomyopathy, undergoing Cesarean section, combined spinal-epidural anesthesia may be an acceptable anesthetic alternative...
- Autoimmune mechanisms as the basis for human peripartum cardiomyopathyAftab A Ansari
Department of Pathology and Laboratory Medicine, Room 4107B Winship Cancer Institute, Emory University School of Medicine, 1365 B Clifton Rd, Atlanta, GA 30322, USA
Clin Rev Allergy Immunol 23:301-24. 2002..A working model for the pathogenesis of this disease is also described herein...
- Risk of warfarin during pregnancy with mechanical valve prosthesesMaurizio Cotrufo
Department of Cardio Thoracic and Respiratory Sciences, V Monaldi Hospital, Naples, Italy
Obstet Gynecol 99:35-40. 2002..To assess the determinants of pregnancy outcome in patients with mechanical valve prostheses anticoagulated with warfarin...
- Maternal deaths due to hypertensive disorders in pregnancyJ Moodley
Department of Obstetrics and Gynaecology, University of KwaZulu Natal, Durban, South Africa
Best Pract Res Clin Obstet Gynaecol 22:559-67. 2008....
- Dose-dependent fetal complications of warfarin in pregnant women with mechanical heart valvesN Vitale
Department of Cardiac Surgery, Medical School, Monaldi Hospital, Second University of Naples, Italy
J Am Coll Cardiol 33:1637-41. 1999..The purpose of this study was to assess the incidence of warfarin fetal complications and whether they are dose-dependent...
- The influence of maternal hypertension on low birth weight: differences among ethnic populationsJ Fang
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Ethn Dis 9:369-76. 1999..To determine the influence of maternal hypertension on the risk of low birth weight among white, black, and Hispanic residents of New York City...
- Peripartum cardiomyopathyH Ardehali
Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Minerva Cardioangiol 51:41-8. 2003..Patients who fail to recover may require inotropic therapy, intra-aortic balloon pump and left ventricular assist device as needed. Cardiac transplantation should be considered for patients who fail therapy...
- Enoxaparin treatment in women with mechanical heart valves during pregnancyJ A Rowan
Department of Obstetrics, National Women's Hospital, Auckland, New Zealand
Am J Obstet Gynecol 185:633-7. 2001..Further data are required before use of enoxaparin during pregnancy in women with mechanical heart valves can be recommended...
- Low-molecular-weight heparin for the prevention and treatment of venous thromboembolism in pregnancyM D McColl
Haematology Department, Crosshouse Hospital, Kilmarnock, United Kingdom
Curr Opin Pulm Med 10:371-5. 2004..However, until recently, evidence in pregnant women was lacking, despite the increasing use of LMWHs during pregnancy in clinical practice. This review covers recent literature on the use of LMWHs in relation to pregnancy...
- A prospective trial that demonstrates that dalteparin requirements increase in pregnancy to maintain therapeutic levels of anticoagulationLinda A Barbour
Department of Medicine, University of Colorado Health Sciences Center, Denver, USA
Am J Obstet Gynecol 191:1024-9. 2004..The purpose of this study was to determine whether standard therapeutic doses of dalteparin maintain peak therapeutic levels of anticoagulation during pregnancy...
- Anticoagulation of pregnant women with mechanical heart valvesJeffrey S Ginsberg
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Arch Intern Med 163:694-8. 2003..We believe a consensus conference among experts in the field to identify key unresolved issues and a commitment by the FDA and industry to perform appropriate studies are now critical...
- Pregnancy and peripartum cardiomyopathy. A comparative and prospective studyWalkiria Samuel Avila
Instituto do Coração do Hospital das Clínicas FMUSP, Sao Paulo, Brazil
Arq Bras Cardiol 79:484-93. 2002..To assess pregnancy outcome in women with peripartum cardiomyopathy and to compare it with idiopathic cardiomyopathy...
- Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorderJean Christophe Gris
Hematology Laboratory, University Hospital, Nimes, France
Blood 103:3695-9. 2004..As there is no argument to prove that low-dose aspirin may have been deleterious, these results support enoxaparin use during such at-risk pregnancies...
- Ruptured renal artery aneurysm in a pregnant woman with solitary kidneyF Ghanavati
Ashington General Hospital, Department of Obstetrics and Gynaecology, Ashington, Northumberland, UK
J Obstet Gynaecol 23:564-6. 2003
- Ruptured renal artery aneurysm during pregnancy: successful ex situ repair and autotransplantationH Lacroix
Department of Vascular Surgery, UZ Gasthuisberg, Leuven, Belgium
J Vasc Surg 33:188-90. 2001..We report the case of a mother and fetus who both survived acute rupture of a renal artery aneurysm after treatment with ex situ repair and autotransplantation...
- Pregnancy outcomes in women with congenital heart diseasePaul Khairy
Boston Adult Congenital Heart Service, Brigham and Women s Hospital, Boston, MA, USA
Circulation 113:517-24. 2006..Pregnant women with congenital heart disease are at increased risk for cardiac and neonatal complications, yet risk factors for adverse outcomes are not fully defined...
- Associations of prepregnancy cardiovascular risk factors with the offspring's birth weightPal R Romundstad
Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway
Am J Epidemiol 166:1359-64. 2007..These findings suggest that low as well as high birth weight of the offspring may indicate increased cardiovascular risk for the mother...
- Hypertensive disorders of pregnancy: a UK-based perspectiveManju Chandiramani
King s College London, Division of Reproduction and Endocrinology, London, UK
Curr Opin Obstet Gynecol 20:96-101. 2008
- What matters in preeclampsia are the associated adverse outcomes: the view from CanadaPeter von Dadelszen
Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada
Curr Opin Obstet Gynecol 20:110-5. 2008
- Chronic hypertension related to risk for preterm and term small for gestational age birthsJanet M Catov
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh Pennsylvania, USA
Obstet Gynecol 112:290-6. 2008..To identify factors associated with SGA that may involve a placental pathogenesis, we related chronic hypertension and other maternal factors that may be markers of endothelial dysfunction to preterm compared with term SGA births...
- Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control studyMarie Josée Martel
Faculty of Pharmacy, Universite de Montreal, CP 6128, Succursale Centre Ville, Montreal, QC, Canada H3C 3J7
BMJ 330:230. 2005..To determine whether the use of inhaled corticosteroids during pregnancy increases the risk of pregnancy induced hypertension and pre-eclampsia among asthmatic women...
- Comparison between HELLP syndrome, chronic hypertension, and superimposed preeclampsia on chronic hypertension without HELLP syndromeMehmet A Osmanagaoglu
Department of Obstetrics and Gynecology, Medicine School of Karadeniz Technical University, 61080 Trabzon, Turkey
J Perinat Med 32:481-5. 2004..To compare perinatal outcome of patients with HELLP syndrome to that of patients with chronic hypertension and superimposed preeclampsia on chronic hypertension without HELLP syndrome...
- Effect of preeclampsia on blood pressure in newborn very low birth weight infantsJyothi Swarup
Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Hypertens Pregnancy 24:223-34. 2005..To test the hypothesis that very low birth infants born to mothers with preeclampsia have higher blood pressure over the first week of life than infants whose mothers did not have preeclampsia...
- Outcome of pregnancy after organ transplantation: a retrospective survey in ItalyRoberto Miniero
Department of Paediatrics, University of Turin, Ospedale San Luigi di Orbassano, Reg Gonzole 10, 10043, Orbassano, Italy
Transpl Int 17:724-9. 2005..According to our previous experience, our study shows that patients who have undergone organ transplantation can give birth to healthy infants as long as they are monitored accurately during pregnancy...
- Invited commentary: Timing and types of cardiovascular risk factors in relation to offspring birth weightRoberta B Ness
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Am J Epidemiol 166:1365-7. 2007..Without all such time points, life course effects will remain only partially understood. It is hoped that studies such as the forthcoming National Children's Study will generate critical understanding of this issue...
- Acute coronary syndrome and preeclampsiaSepideh Nabatian
Department of Cardiology, Lutheran General Hospital, Park Ridge, Illinois 60068, USA
Obstet Gynecol 106:1204-6. 2005..Approximately 150 cases of myocardial infarction during pregnancy have been documented in the literature worldwide (predominantly anterior wall). However, elevated troponin levels have been reported in patients with preeclampsia...
- Antihypertensive therapy in patients with pre-eclampsia: A prospective randomised multicentre study comparing dihydralazine with urapidilJuergen R Wacker
Department of Obstetrics and Gynecology Bruchsal, Furst Stirum Klinik Bruchsal, Teaching Hospital of the University of Heidelberg, Gutleutstrasse 1 14, D 76646 Bruchsal, Baden Wuerttemberg, Germany
Eur J Obstet Gynecol Reprod Biol 127:160-5. 2006..Another particularly effective and better tolerable antihypertensive is urapidil. Yet only a few studies on limited patient collectives have been published on the clinical experience with urapidil in PIH...
- Oocyte donation in patients with Turner's syndrome: a successful technique but with an accompanying high risk of hypertensive disorders during pregnancyD Bodri
Clinica Eugin, c Entença 293 295, 08029 Barcelona and Hospital Clínic, IDIBAPS, University of Barcelona, Spain
Hum Reprod 21:829-32. 2006..Few data are available on pregnancy rate and obstetrical outcome after oocyte donation in Turner's syndrome patients. We conducted a retrospective analysis on the outcome of this subgroup...
- Contemporary concepts of the pathogenesis and management of preeclampsiaKristine Y Lain
Magee Womens Research Institute and Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA
JAMA 287:3183-6. 2002
- Pregnancy in women with Type 2 diabetes: who takes metformin and what is the outcome?R C E Hughes
Department of Medicine, Auckland, New Zealand
Diabet Med 23:318-22. 2006..To review pregnancy outcomes in women with Type 2 diabetes (Type 2 DM), comparing women treated with those not treated with metformin...
- Perinatal outcomes, blood pressure patterns and risk assessment of superimposed preeclampsia in mild chronic hypertensive pregnancyStefano Raffaele Giannubilo
Department of Obstetrics and Gynecology, Marche Polytechnic University at Salesi Hospital, via Corridoni 11, 60123 Ancona, Italy
Eur J Obstet Gynecol Reprod Biol 126:63-7. 2006..Assessment of perinatal outcomes, blood pressure (BP) patterns and risk of superimposed preeclampsia in a population with mild chronic hypertension...
- Preeclampsia and pregnancy loss in women with a history of venous thromboembolism and prophylactic low-molecular-weight heparin (LMWH) during pregnancyGuelay Alguel
Department of Internal Medicine I, Medical University Vienna, Vienna, Austria
Thromb Haemost 96:285-9. 2006..There was a trend towards a higher risk of preeclampsia, and these women should be carefully monitored for this complication...
- [High plasmatic androgen levels in women affected with pregnancy-induced hypertension]Donatella Gerulewicz-Vannini
Servicio de Ginecologia y Obstetricia, Hospital General Dr José Gregorio Hernández
Rev Invest Clin 58:228-33. 2006....
- Relation of parity to pregnancy outcome in a rural community in ZimbabweF M Majoko
Department of Obstetrics and Gynaecology, University of Zimbabwe, Harare, Zimbabwe
Afr J Reprod Health 8:198-206. 2004..48; 95% 1.31- 1.67). In conclusion, nulliparous women had an increased risk of pregnancy complications. High parity women with no previous complicated pregnancy were at low risk of complications...
- Impact of pregnancy on the outcome of kidney transplantationN Kashanizadeh
Nephrology and Urology Research Center NURC, Baqiyatallah Medical Sciences University, Tehran, Iran
Transplant Proc 39:1136-8. 2007..We, thus, compared two groups of kidney transplant recipients in terms of patient survival and allograft function: those who did versus did not conceive posttransplant...
- [Maternal and perinatal prognosis of pregnancy with chronic hypertension and analysis of associated factors]Yu Sun
Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China
Zhonghua Fu Chan Ke Za Zhi 42:434-7. 2007..To analyze the pregnant outcome of women with chronic hypertension, and to investigate the high risk factors associated with harmful maternal and perinatal prognosis...
- [Vascular complications and their effect on fetal-maternal outcome and therapeutic approach in diabetic women]Ewa Wender-Ozegowska
Klinika Połoznictwa i Chorób Kobiecych, Katedry Ginekologii i Połoznictwa AM im K Marcinkowskiego w Poznaniu
Ginekol Pol 75:385-96. 2004..The aim of this study was to discuss the update guidelines for managing diabetic patients with vascular complications before and during the course of pregnancy...
- Nutrient intake and hypertensive disorders of pregnancy: Evidence from a large prospective cohortC D Morris
Division of Medical Informatics and Outcomes Research, Oregon Health Sciences University, USA
Am J Obstet Gynecol 184:643-51. 2001..CONCLUSION: We found no evidence in this study for a significant association of hypertensive disorders of pregnancy with any of the 23 nutrients measured...
- The impact of parity on the incidence of HELLP syndrome and small for gestational age infants in hypertensive pregnant womenKeith P Williams
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT, USA
J Obstet Gynaecol Can 24:485-9. 2002....
- Prepidil compared to Propess for cervical ripeningA Vollebregt
Department of Obstetrics and Gynaecology, Spaarne Ziekenhuis Haarlem, Afdeling Verloskunde en Gynaecologie, Postbus 1644, 2003 Haarlem BR, The Netherlands
Eur J Obstet Gynecol Reprod Biol 104:116-9. 2002..To compare the efficacy and safety of intracervical PGE(2) gel (Prepidil) with intravaginal PGE(2) insert (Propess) in cervical ripening and induction of labour...
- Association between fetal nuchal translucency thickness in first trimester and subsequent gestational hypertension and preeclampsiaMing Song Tsai
Prenatal Diagnosis Center, Cathay General Hospital, Taipei, Taiwan
Prenat Diagn 22:747-51. 2002..However, the sensitivity of fetal NT measurement in first trimester is not sufficient as a single marker for predicting the pregnant women at risk for subsequent PAH...
- Factors influencing the obstetric and perinatal outcome after oocyte donationGalit Sheffer-Mimouni
Departments of Obstetrics and Gynecology, The Lis Maternity Hospital, 6 Weizman St, Tel Aviv 46427, Israel
Hum Reprod 17:2636-40. 2002..We evaluated interactions between perinatal outcome after oocyte donation and various maternal factors...
- The myth of transient hypertension: descriptor or disease process?D A Terrone
Department of Obstetrics and Gynecology, Saint Barnabas Medical Center, Livingston, New Jersey, USA
Am J Perinatol 18:73-7. 2001..Transient hypertension occurs more often than expected, however, it appears to be of limited clinical significance...
- Prognostic value of absolute versus relative rise of blood pressure in pregnancyHe Onah
Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Teaching Hospital, Enugu, Nigeria
Afr J Reprod Health 6:32-40. 2002....
- Obstetric causes for delivery of very-low-birth-weight babies at Tygerberg HospitalE S Odendaal
Department of Obstetrics and Gynecology, Tygerberg Hospital, W Cape, South Africa
S Afr Med J 93:61-4. 2003
- Chronic hypertension in pregnancyJ C Livingston
Prenatal Diagnostic Center, Carilion Health System, Roanoke, VA 24013, USA
Minerva Ginecol 55:1-13. 2003..Fetal complications include prematurity, low birth weight, and perinatal death. Careful antepartum, intrapartum and postpartum management of women with high-risk chronic hypertension in pregnancies may reduce morbidity and mortality...
- Hypertension in pregnancy and preeclampsia. Knowledge and clinical practice among obstetrician-gynecologistsJohn T Repke
Department of Obstetrics and Gynecology, University of Nebraska Medical Center, 983255 Nebraska Medical Center, Omaha, NE 68198 3255, USA
J Reprod Med 47:472-6. 2002..To examine the knowledge and practice patterns of obstetrician-gynecologists concerning management of hypertensive disorders of pregnancy...
- Hypertensive disorders of pregnancy in women with Type 1 and Type 2 diabetesT Cundy
Department of Medicine, Faculty of Medicine and Health Sciences, University of Auckland and, Diabetes Pregnancy Clinic, National Women s Hospital, Auckland, New Zealand
Diabet Med 19:482-9. 2002..The aim of this study was to compare the incidence and outcomes of, and risk factors for, hypertension in pregnancy in women with Type 1 and Type 2 diabetes...
- Low dose acetylsalicylic acid in prevention of pregnancy-induced hypertension and intrauterine growth retardation in women with bilateral uterine artery notchesMerja Vainio
Department of Obstetrics and Gynaecology Tampere University Hospital, Finland
BJOG 109:161-7. 2002....
- The renin-aldosterone system during normal and hypertensive pregnancyA Elsheikh
1st Department of Obstetrics and Gynecology, University of Athens, Alexandra Maternity Hospital, Greece
Arch Gynecol Obstet 264:182-5. 2001..Thus, we conclude that aldosterone biology seems to be directly or indirectly involved in the etiology of gestational hypertension independently of renin levels...
- Fetal loss rate associated with cordocentesis at midgestationT Tongsong
Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand
Am J Obstet Gynecol 184:719-23. 2001..However, there were no significant differences in other obstetric complications between the study and control groups. CONCLUSION: The incremental fetal loss rate associated with cordocentesis at midgestation was about 1.4%...
- Mild gestational hypertension remote from term: progression and outcomeJ R Barton
Maternal-Fetal Medicine, Central Baptist Hospital, Lexington, Kentucky 40503, USA
Am J Obstet Gynecol 184:979-83. 2001..6%. The development of proteinuria is associated with an earlier gestational age at delivery, lower birth weight, and an increased incidence of small-for-gestational age newborns...
- Doppler ultrasound screening predicts recurrence of poor pregnancy outcome in subsequent pregnancies, but not the recurrence of PIH or preeclampsiaM W Aardema
Department of Obstetrics and Gynaecology, Division of Obstetrics and Perinatal Medicine, University Hospital Groningen, Groningen, The Netherlands
Hypertens Pregnancy 19:281-8. 2000..In contrast, gestational hypertension and preeclampsia with normal pregnancy outcome were not significantly predicted by uterine artery screening...
- REPERFUSION EFFECTS ON CEREBRAL ARTERY FUNCTIONMarilyn Cipolla; Fiscal Year: 2003..Therefore, Aim 3 will investigate the effects of two types of thrombolytic agents (tissue-type and urokinase) on cerebral artery function, including myogenic processes. ..
- Cerebral Arteriole Function during Hyperglycemic StrokeMarilyn Cipolla; Fiscal Year: 2009....
- Mechanisms of myometrial healing and regenerationCatalin Buhimschi; Fiscal Year: 2006....
- Role of VEGF in Neonatal Pulmonary HypertensionTheresa Grover; Fiscal Year: 2008..These studies will provide an integrated approach to the hypothesis, incorporating whole animal physiology coupled with molecular and cellular studies. ..
- Inflammation and Ovarian CancerClareann Bunker; Fiscal Year: 2008..In particular, NSAID use may prove to be a potentially important chemopreventative for this often-fatal disease. ..
- Renal Microcirculatory and Tubular DynamicsJoey Granger; Fiscal Year: 2004....
- ABNORMAL PRESSURE NATRIURESIS IN HYPERTENSIONJoey Granger; Fiscal Year: 2009..a decrease in renal medullary production of 20 HETE 3) To test the hypothesis that abnormalities in renal medullary endothelin production and/or ETB receptor function mediate the hypertension in Dahl salt-sensitive rats ..
- GENETIC MECHANISMS OF ESTROGEN ATHEROPROTECTIONAmparo Villablanca; Fiscal Year: 2003..Advances in our basic understanding of mechanisms of hormone action could lead to more effective strategies for treatment of coronary artery disease in both men and women. ..
- Racial Segregation & Disparities in Cancer OutcomesJennifer Haas; Fiscal Year: 2007..The proposed study would provide empirical evidence that could give impetus to area-based interventions to reduce cancer disparities. ..
- Targets for New Therapeutics for SLEJane Salmon; Fiscal Year: 2002..abstract_text> ..
- Blood Pressure in Postmenopausal Women: A GCRC StudyELLEN SEELY; Fiscal Year: 2007..Thus, funding of this proposal will allow Dr. Seely to expand her own research career and simultaneously provide time to expand her mentorship role. ..
- Yoga and Indices of Cardiovascular Risk in Older WomenKAREN KIM INNES; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Impact of LEEP on cervical length and secretionsAudrey Saftlas; Fiscal Year: 2007..Paired statistical techniques, simple and multivariate linear regression, ANOVA, two-way repeated measures ANOVA, and ANCOVA will be used. [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
- Estrogen Modulates Injury-Induced InflammationSuzanne Oparil; Fiscal Year: 2007..These fundamental mechanistic studies will enhance our understanding of the pathobiology of vascular disease, particularly as it occurs in aging women, and will provide the basis for development of novel therapeutic strategies. ..
- Role of Ca channels in congenital heart blockMohamed Boutjdir; Fiscal Year: 2007..unreadable] [unreadable]..
- Computerized EMR-Assisted Smoking Cessation (CEASCE)Jennifer Haas; Fiscal Year: 2007..Future Directions: Evaluate whether CEASCE can serve as a prototype for other common primary care problems that require counseling for behavior change. [unreadable] [unreadable]..
- Complement as a Mediator of Recurrent MiscarriagesJane Salmon; Fiscal Year: 2008..In addition, our studies will provide insights into mechanisms by which complement-induces disease and suggest means to prevent, arrest, or modify complement-mediated inflammatory disorders. [unreadable] [unreadable]..
- Mechanism of aPL antibody-induced Pregnancy lossJane E Salmon; Fiscal Year: 2010..Additionally, understanding how aPL antibodies "cause" pregnancy loss may translate into new concepts about maternal-fetal tolerance and miscarriages in general and benefit women with non-APS- related pregnancy complications. ..
- Intimate Partner Violence in a Women's Health Clinic PopulationAudrey Saftlas; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Mineral Metabolism and Cardiovascular Risk among Older AdultsBryan Kestenbaum; Fiscal Year: 2009..Proposed analyses aim to clarify the roles of individual mineral markers with respect to CV health among older adults and to pave the way for future trials that target these markers as a means to improve CV outcomes. ..
- Relationship between Periodontal Disease and Gestational Diabetes MellitusXu Xiong; Fiscal Year: 2008..Improving oral health and treating periodontal disease before and during pregnancy may reduce maternal and perinatal morbidity associated with GDM and prevent type 2 diabetes after pregnancy. [unreadable] [unreadable] [unreadable]..
- Outcomes of Perinatal StrokeMeredith Golomb; Fiscal Year: 2008..During the last year of the study, she plans to apply for an R01 grant to set up a pilot clinical trial. [unreadable] [unreadable]..
- MIND-BODY-BEHAVIORAL MED CLINICAL TRIALS INFRASTRUCTUREKarina Davidson; Fiscal Year: 2008..The ultimate goal will be to make our findings available to 3 target audiences: 1) the network of investigators at Columbia; 2) the behavioral medicine community; and 3) the general medical community. ..
- Prospective Investigation for Pulmonary Embolism Dx IIIPaul Stein; Fiscal Year: 2008..abstract_text> ..
- Genetic Basis of Aortic Aneurysms/DissectionsDianna Milewicz; Fiscal Year: 2009..Therefore, identification of the genes that predispose individuals to TAAD is critical in preventing premature deaths due to dissections. ..
- MOLECULAR MECHANISMS OF CD4+ T CELL DYSFUNCTION IN SIVAftab Ansari; Fiscal Year: 2009..abstract_text> ..
- Cardiac Outcomes Associated with Renal OsteodystrophyBryan Kestenbaum; Fiscal Year: 2007..The proposed study aims to shed light on the relationship between a common renal related metabolic disorder and the epidemic burden of CVD found among this patient population. ..
- HIV INFECTION/COCAINE EFFECT ON CARDIOVASCULAR PATHOLOGYAftab Ansari; Fiscal Year: 2003..We reason that such studies may provide unique insights on the relationship between the effects of cocaine and HIV infection in the pathogenesis of cardiovascular disease. ..
- MATERNAL HEALTH STATUS AND ADVERSE BIRTH OUTCOMESJennifer Haas; Fiscal Year: 2002..Such interventions should begin from the premise that improved maternal and infant outcomes can only come from improved maternal health. ..
- PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-IIPaul Stein; Fiscal Year: 2003..4) The team of investigators is strong, and has collaborated previously in successful research in PE. ..
- Maternal-Fetal HLA Sharing and Risk of PreeclampsiaAudrey Saftlas; Fiscal Year: 2004..05. The proposed study may be the first to examine the effects of maternal-fetal HLA sharing in an adequately powered epidemiological framework. ..
- CD4 T Cell Activation in SIV+Disease Resistant MangabeysAftab Ansari; Fiscal Year: 2004..abstract_text> ..
- GENETIC EXPRESSION OF RISK GENES IN HYPERTENSIONELLEN SEELY; Fiscal Year: 2004....
- DOMESTIC ABUSE IN PREGNANCY AND ADVERSE BIRTH OUTCOMESAudrey Saftlas; Fiscal Year: 2004..abstract_text> ..
- CHARACTERIZING MICROFIBRIL ABNORMALITIES IN SCLERODERMADianna Milewicz; Fiscal Year: 2003..The research proposed in this grant will determine the contribution of abnormalities in fibrillin-1-containing microfibrils to the activation of fibroblasts, which leads to the fibrosis that characterizes SSc. ..
- ADVENTITIAL RESPONSE TO VASCULAR INJURY: ESTROGENSuzanne Oparil; Fiscal Year: 2003..These fundamental mechanistic studies will establish more rational strategies for therapeutic intervention in vascular diseases, including the basis for future gene therapy. ..
- Modeling Complex Exposures and Reproductive OutcomesAmy Herring; Fiscal Year: 2005..The methods will be applied to vaginal bleeding and duration of gestation using the Pregnancy, Infection, and Nutrition study data but have broad applications in reproductive health, epidemiology, and other areas. ..
- Etiologic Heterogeneity in Preterm DeliveryClaudia Holzman; Fiscal Year: 2005..This comprehensive study aims to unify both approaches into a coherent causal framework based on a foundation of specific placental findings that we hypothesize underlie several routes to PTD. ..
- Fetal Determinants of AtherosclerosisWulf Palinski; Fiscal Year: 2006..These studies should yield fundamentally new insights into in utero programming and atherogenic mechanisms, and may establish a novel preventive approach. ..
- Role of T Cell Immunity in Primate AIDSAftab Ansari; Fiscal Year: 2006....
- Conditioned Placebo Effects & Treatment of HypertensionThomas Pickering; Fiscal Year: 2005..The demonstration of a conditioned placebo effect that produces a sustained reduction of BP could result in more economical treatment with fewer side effects. ..
- Neighborhood Disparities and Access to Cardiac CareJing Fang; Fiscal Year: 2003..This would be important for policy to eliminate the health disparity. ..
- MANAGEMENT OF PATIENTS WITH SUSPECTED PULMONARY EMBOLISHSuman Rathbun; Fiscal Year: 2005..abstract_text> ..
- Duke Center for Geospatial Medicine (RMI)Marie Lynn Miranda; Fiscal Year: 2006..Using neural tube defects as a prototype health endpoint, we will develop a generalized framework for applying these methods to a wide variety of health endpoints, including autism, asthma, ADHD, and obesity. [unreadable] [unreadable]..
- PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-IIVictor Tapson; Fiscal Year: 2003..abstract_text> ..
- Brown University BIRCWH Career Development ProgramDONALD COUSTAN; Fiscal Year: 2006..This interdisciplinary and cross-institutional program will provide a new cadre of academic investigators who will further the scientific database and improved the health status of women. ..