scarlet fever

Summary

Summary: Infection with group A streptococci that is characterized by tonsillitis and pharyngitis. An erythematous rash is commonly present.

Top Publications

  1. ncbi Outbreak of scarlet fever caused by an erythromycin-resistant Streptococcus pyogenes emm22 genotype strain in a day-care center
    L E Espinosa de los Monteros
    , Mexico DF, Mexico
    Pediatr Infect Dis J 20:807-9. 2001
  2. pmc Association of the shuffling of Streptococcus pyogenes clones and the fluctuation of scarlet fever cases between 2000 and 2006 in central Taiwan
    Chien Shun Chiou
    The Central Region Laboratory, Center for Research and Diagnostics, Centers for Disease Control, Taichung City 40855, Taiwan
    BMC Microbiol 9:115. 2009
  3. doi Characteristics of Streptococcus pyogenes strains isolated from Chinese children with scarlet fever
    Yunmei Liang
    Beijing Children s Hospital, Affiliated to the Capital Medical University, Beijing, China
    Acta Paediatr 97:1681-5. 2008
  4. ncbi [Comparison of predictive effect between the single auto regressive integrated moving average (ARIMA) model and the ARIMA-generalized regression neural network (GRNN) combination model on the incidence of scarlet fever]
    Yu Zhu
    Department of Epidemiology and Health Statistics, Anhui Medical University, Hefei 230032, China
    Zhonghua Liu Xing Bing Xue Za Zhi 30:964-8. 2009
  5. pmc Molecular characterization of the 2011 Hong Kong scarlet fever outbreak
    Herman Tse
    Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region, China
    J Infect Dis 206:341-51. 2012
  6. ncbi Molecular epidemiology of group A streptococcus causing scarlet fever in northern Taiwan, 2001-2002
    Ying Yan Chen
    Research and Diagnostics Center, Centers for Disease Control, Taipei, Taiwan
    Diagn Microbiol Infect Dis 58:289-95. 2007
  7. pmc Epidemiology and molecular characterization of Streptococcus pyogenes recovered from scarlet fever patients in central Taiwan from 1996 to 1999
    Chien Shun Chiou
    The Central Branch Office, Center for Disease Control, 5F 20 Wen Sin South 3rd Rd, Taichung City 408, Taiwan
    J Clin Microbiol 42:3998-4006. 2004
  8. ncbi Report and analysis of a scarlet fever outbreak among adults through food-borne transmission in China
    Shi Gui Yang
    Key Laboratory of Infectious Diseases, Ministry of Health of China, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
    J Infect 55:419-24. 2007
  9. pmc Molecular analysis of group A streptococcal isolates associated with scarlet fever in southern Taiwan between 1993 and 2002
    Jing Jou Yan
    Department of Pathology, College of Medicine National Cheng Kung University, Tainan, Taiwan
    J Clin Microbiol 41:4858-61. 2003
  10. ncbi Modelling the dynamics of scarlet fever epidemics in the 19th century
    S R Duncan
    Department of Engineering Science, Oxford
    Eur J Epidemiol 16:619-26. 2000

Research Grants

  1. CYTOLYSIN-MEDIATED TRANSLOCATION IN S. PYOGENES VIRULENC
    Michael G Caparon; Fiscal Year: 2010
  2. PROPERTIES OF STREPTOCOCCAL M PROTEIN
    Vincent A Fischetti; Fiscal Year: 2010
  3. PROPERTIES OF STREPTOCOCCAL M PROTEIN
    Vincent Fischetti; Fiscal Year: 2009
  4. Heme Acquisition in Group A Streptococcus
    Benfang Lei; Fiscal Year: 2005
  5. Heme Acquisition in Group A Streptococcus
    Benfang Lei; Fiscal Year: 2004
  6. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2006
  7. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2002
  8. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2004
  9. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2003
  10. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2005

Detail Information

Publications154 found, 100 shown here

  1. ncbi Outbreak of scarlet fever caused by an erythromycin-resistant Streptococcus pyogenes emm22 genotype strain in a day-care center
    L E Espinosa de los Monteros
    , Mexico DF, Mexico
    Pediatr Infect Dis J 20:807-9. 2001
    We report an outbreak of scarlet fever and pharyngeal colonization with Streptococcus pyogenes in a day-care center in Mexico City. The outbreak strain was resistant to erythromycin but susceptible to clindamycin...
  2. pmc Association of the shuffling of Streptococcus pyogenes clones and the fluctuation of scarlet fever cases between 2000 and 2006 in central Taiwan
    Chien Shun Chiou
    The Central Region Laboratory, Center for Research and Diagnostics, Centers for Disease Control, Taichung City 40855, Taiwan
    BMC Microbiol 9:115. 2009
    The number of scarlet fever occurrences reported between 2000 and 2006 fluctuated considerably in central Taiwan and throughout the nation...
  3. doi Characteristics of Streptococcus pyogenes strains isolated from Chinese children with scarlet fever
    Yunmei Liang
    Beijing Children s Hospital, Affiliated to the Capital Medical University, Beijing, China
    Acta Paediatr 97:1681-5. 2008
    To analyse the characteristics of Streptococcus pyogenes isolates from Chinese children with scarlet fever.
  4. ncbi [Comparison of predictive effect between the single auto regressive integrated moving average (ARIMA) model and the ARIMA-generalized regression neural network (GRNN) combination model on the incidence of scarlet fever]
    Yu Zhu
    Department of Epidemiology and Health Statistics, Anhui Medical University, Hefei 230032, China
    Zhonghua Liu Xing Bing Xue Za Zhi 30:964-8. 2009
    ..the 'ARIMA-generalized regression neural network (GRNN) combination model' in the research of the incidence of scarlet fever. Establish the auto regressive integrated moving average model based on the data of the monthly incidence on ..
  5. pmc Molecular characterization of the 2011 Hong Kong scarlet fever outbreak
    Herman Tse
    Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region, China
    J Infect Dis 206:341-51. 2012
    A scarlet fever outbreak occurred in Hong Kong in 2011. The majority of cases resulted in the isolation of Streptococcus pyogenes emm12 with multiple antibiotic resistances...
  6. ncbi Molecular epidemiology of group A streptococcus causing scarlet fever in northern Taiwan, 2001-2002
    Ying Yan Chen
    Research and Diagnostics Center, Centers for Disease Control, Taipei, Taiwan
    Diagn Microbiol Infect Dis 58:289-95. 2007
    In this study, 830 Streptococcus pyogenes isolates collected between 2001 and 2002 from patients with scarlet fever in northern Taiwan were analyzed by M protein gene (emm) sequence typing, pulsed-field gel electrophoresis (PFGE), and ..
  7. pmc Epidemiology and molecular characterization of Streptococcus pyogenes recovered from scarlet fever patients in central Taiwan from 1996 to 1999
    Chien Shun Chiou
    The Central Branch Office, Center for Disease Control, 5F 20 Wen Sin South 3rd Rd, Taichung City 408, Taiwan
    J Clin Microbiol 42:3998-4006. 2004
    One hundred seventy-nine Streptococcus pyogenes isolates recovered from scarlet fever patients from 1996 to 1999 in central Taiwan were characterized by emm, Vir, and pulsed-field gel electrophoresis (PFGE) typing methods...
  8. ncbi Report and analysis of a scarlet fever outbreak among adults through food-borne transmission in China
    Shi Gui Yang
    Key Laboratory of Infectious Diseases, Ministry of Health of China, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
    J Infect 55:419-24. 2007
    b>Scarlet fever is caused by group A beta-hemolytic streptococci (GAS)...
  9. pmc Molecular analysis of group A streptococcal isolates associated with scarlet fever in southern Taiwan between 1993 and 2002
    Jing Jou Yan
    Department of Pathology, College of Medicine National Cheng Kung University, Tainan, Taiwan
    J Clin Microbiol 41:4858-61. 2003
    ..between 1993 and 2002 at a Taiwanese university hospital, 77 group A streptococcus isolates associated with scarlet fever were grouped by emm typing and pulsed-field gel electrophoresis...
  10. ncbi Modelling the dynamics of scarlet fever epidemics in the 19th century
    S R Duncan
    Department of Engineering Science, Oxford
    Eur J Epidemiol 16:619-26. 2000
    Annual deaths from scarlet fever in Liverpool, UK during 1848-1900 have been used as a model system for studying the historical dynamics of the epidemics...
  11. pmc Molecular characterization of group A Streptococcus strains isolated during a scarlet fever outbreak
    Luis M Perea-Mejía
    Departamento de Salud Publica, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, DF Mexico, 04510, Mexico
    J Clin Microbiol 40:278-80. 2002
    Forty group A streptococcus (GAS) isolates, recovered during a scarlet fever outbreak, were grouped based on their DdeI restriction profiles from emm amplicons. Twenty-seven isolates were identified by sequencing as emm2...
  12. doi Periprosthetic breast abscess caused by Streptococcus pyogenes after scarlet fever
    Paolo Persichetti
    Campus Bio Medico di Roma University, Rome, Italy
    Ann Plast Surg 60:21-3. 2008
    ..She presented a periprosthetic infection from Streptococcus pyogenes (group A streptococcus, GAS) after scarlet fever. S...
  13. ncbi [Scarlet fever in Poland in 2001]
    Mirosław P Czarkowski
    Zakład Epidemiologii Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 57:33-8. 2003
    In 2001, as compared to 2000, a 29.5% decrease in the number of scarlet fever cases was noted. The incidence was 15.2 per 100,000 population and was one of the lowest since the World War I...
  14. pmc Major outbreak of toxic shock-like syndrome caused by Streptococcus mitis
    Hong Zhou Lu
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Clin Microbiol 41:3051-5. 2003
    ..and May 1991, thousands of patients in the YangZi River Delta area of Jiangsu Province, China, suffered from scarlet fever-like pharyngitis. Fewer cases occurred in subsequent years with the same seasonality...
  15. ncbi Kawasaki disease before kawasaki at Tokyo university hospital
    Noriko Shibuya
    Department of Pediatrics, Sanno Hospital, Tokyo, Japan
    Pediatrics 110:e17. 2002
    ..This study was performed to clarify when KD appeared in Japan...
  16. ncbi [Infectious diseases in Poland in 2000]
    Jacek Mazurek
    Zakład Epidemiologii Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 56:217-25. 2002
    ..Between 1999 and 2000, the most intense decrease in the number of mumps, measles, and scarlet fever cases as an effect of the end of epidemics was observed...
  17. ncbi A young rash on old shoulders--scarlet fever in an adult male
    R J Davies
    Department of Medicine, Queen s Medical Centre, Nottingham, UK
    Lancet Infect Dis 2:750. 2002
  18. ncbi [Scarlet fever in Poland in 2000]
    Mirosław P Czarkowski
    Zakład Epidemiologii Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 56:241-7. 2002
    In 2000, as compared with 1999, a 14% decrease in the number of scarlet fever cases was noted. The incidence was 21.6 per 100,000 population and was one of the lowest since World War II. In particular voivodeships incidence ranged from 9...
  19. ncbi Varicella complicated by scarlet fever
    Taner Yavuz
    Department of Pediatrics, Duzce School of Medicine, Abant Izzet Baysal University, Turkey
    Indian Pediatr 40:1002-4. 2003
    We report a 3-year-old boy with varicella complicated by cellulitis and scarlet fever. He developed a typical rash of scarlet fever following the onset of varicella. Streptococcus pyogenes was isolated from the ulcers due to varicella...
  20. ncbi Enterotoxin B is the predominant toxin involved in staphylococcal scarlet fever in Taiwan
    Chih Chien Wang
    Department of Pediatrics, Tri Service General Hospital, Taipei, Taiwan
    Clin Infect Dis 38:1498-502. 2004
    This study retrospectively reviewed all pediatric cases of staphylococcal scarlet fever (SSF) that occurred during a 10-year period in a 1400-bed tertiary medical center in northern Taiwan...
  21. ncbi Prevalence and persistence of certain serologic types of Streptococcus pyogenes in metropolitan Tokyo
    Tatsu Iimura
    Tokyo Metropolitan Toshima Hospital, Tokyo, Japan
    J Infect Chemother 12:53-62. 2006
    ..isolated within 1 week of admission from patients admitted to the Tokyo Metropolitan Toshima Hospital for scarlet fever in the 23-year period between 1956 and 1978...
  22. ncbi [Epidemiologic research to assess some socioeconomic aspects of health care in patients with infections caused by group A beta hemolytic streptococcus and their complications]
    A Chiriţă
    Universitatea de Medicină si Farmacie Gr T Popa Iaşi, Facultatea de Medicina
    Rev Med Chir Soc Med Nat Iasi 109:131-5. 2005
    ..streptococcus (ABHS) infections and by their complications, assessed on 10948 inpatients with angina, 323 with scarlet fever, and 644 with erysipelas, hospitalized in the City of Galati, between 2000-2003...
  23. ncbi Dual role of infections as risk factors for coronary heart disease
    Erkki Pesonen
    Pediatric Cardiology, University Hospital of Lund, Lund, Sweden
    Atherosclerosis 192:370-5. 2007
    ..The aim of the study was to explore whether exposure to microbial agents determines the prevalence of acute coronary events...
  24. ncbi [Diagnostic image (281). A girl with fever, a sore throat and a rash]
    J M P J Breur
    Isala Klinieken, Amalia Kinderafdeling, Zwolle
    Ned Tijdschr Geneeskd 150:1508. 2006
    b>Scarlet fever was diagnosed in a girl with high fever, a sore throat and exanthema marginatum.
  25. ncbi Bullous necrotic lesion of the penis
    M Akkilic
    J Eur Acad Dermatol Venereol 20:1024-6. 2006
  26. ncbi [Scarlet fever in Poland in 2003]
    Mirosław P Czarkowski
    Zakład Epidemiologii, Państwowego Zakładu Higieny, Warszawa
    Przegl Epidemiol 59:235-40. 2005
    Following the last epidemic in 1995 the scarlet fever incidence in Poland has been gradually decreasing. The downward trend continued in 2003, with overall incidence rate of 10.1 per 100,000...
  27. ncbi [Diagnosis at a glance. Measles, rubella or scarlet fever?]
    H S Fuessl
    Bezirkskrankenhaus Haar bei München
    MMW Fortschr Med 147:73. 2005
  28. ncbi [Epidemiologic aspects of group A betahemolytic streptococcus infections in Galaţi County between 1990 and 2000]
    A Chiriţă
    Direcţia de Sănătate Publică a judeţului Galaţi, Universitatea de Medicină si Farmacie Gr T Popa Iaşi, Facultatea de Medicina
    Rev Med Chir Soc Med Nat Iasi 108:299-304. 2004
    ..Between 1990-2000, in the Galati County, scarlet fever registered values of morbidity with a yearly variability between 8.2 and 54.1 cases/100,000 inhabitants...
  29. ncbi Childhood infections and risk of wheezing and allergic sensitisation at age 7-8 years
    Monique Mommers
    Institute for Hygiene and Environmental Medicine, R WTH Aachen, Germany
    Eur J Epidemiol 19:945-51. 2004
    ..Aim of this study was to investigate the association between childhood infections and the occurrence of wheeze and allergic sensitisation in 7-8-year-old Dutch and German children...
  30. ncbi [Scarlet fever in Poland in 2002]
    Mirosław P Czarkowski
    Zakład Epidemiologii Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 58:35-9. 2004
    Following the last epidemic in 1995 the scarlet fever incidence in Poland has been gradually decreasing, on average 20% per year. The downward trend continued in 2002, the overall incidence rate being 10.6 per 100,000...
  31. ncbi [Infectious diseases in Poland in 2002]
    Andrzej Zielinski
    Zakład Epidemiologii Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 58:9-19. 2004
    ..4 (ślaskie). As in previous years, the highest number of deaths was caused by tuberculosis and its late sequels (35.4%). Attention should be given to the increased number of deaths due to sepsis (33.6%, without neonatal sepsis)...
  32. doi Beta-haemolytic group A streptococci emm75 carrying altered pyrogenic exotoxin A linked to scarlet fever in adults
    Hongjun Dong
    Department of Infectious Disease, Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China
    J Infect 56:261-7. 2008
    To determine the etiological cause of a food-borne outbreak of scarlet fever in adults.
  33. ncbi Index of suspicion
    Ara Festekjian
    Children s Hospital of Los Angeles, Los Angeles, California, USA
    Pediatr Rev 27:189-94. 2006
  34. ncbi [A dying clinical diagnosis of scarlet fever--the last sixteen years survey]
    Y Takizawa
    Minamigaoka Branch, Sapporo City General Hospital
    Kansenshogaku Zasshi 65:996-1002. 1991
    11,119 patients with scarlet fever admitted in the last sixteen years, from 1973 to 1988, to Sapporo City General Hospital, were studied statistically on symptoms and laboratory findings. The results were summarized as follows: 1...
  35. ncbi [Scarlet fever in Poland in 1999]
    M P Czarkowski
    , 00-791 Warszawa
    Przegl Epidemiol 55:37-43. 2001
    Following the last compensatory epidemic of scarlet fever in 1995 the number of cases decreased, although the decrease rate was low. In 1999 the incidence rate for the entire country was 25.1 per 100,000 (range from 11.5 to 38...
  36. ncbi Heat shock protein 90 antibodies in autism
    M Evers
    Department of Psychiatry, Seaver Autism Research Center, Mt Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Mol Psychiatry 7:S26-8. 2002
  37. doi Importance of communication between medical specialties: a case series
    L Bayam
    Department of Orthopaedics, Royal Bolton Hospital, UK
    Injury 39:623-6. 2008
  38. ncbi Stick out your tongue and say...uh, oh!
    Sally Walsh
    Pediatric Associates of Norwood, Boston, Massachusetts, USA
    J Pediatr Health Care 19:247-8, 263-4. 2005
  39. ncbi [Does depot penicillin over a long term increase the antistreptolysin titer?]
    R W Braun
    Dtsch Med Wochenschr 130:1230. 2005
  40. ncbi Hepatitis in scarlet fever
    Keren Elishkewitz
    Department of Pediatrics C, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Isr Med Assoc J 6:569-70. 2004
  41. ncbi Hepatitis and hematuria in scarlet fever
    Ayla Guven
    Department of Pediatrics, Gazi University Faculty of Medicine, Ankara, Turkey
    Indian J Pediatr 69:985-6. 2002
    b>Scarlet fever is a common and usually benign course when treated properly. Hepatitis due to scarlet fever has been described mostly in adults...
  42. ncbi [Clinical aspects of streptococcal and staphylococcal toxinic diseases]
    D Floret
    Service d urgence et de réanimation pédiatriques, Hopital Edouard Herriot, Place d Arsonval, 69437 Lyon, France
    Arch Pediatr 8:762s-768s. 2001
    ..It is a mild disease with a favourable outcome within a few days. Scarlet fever is related to the streptococcal erythrogenic toxins. The classic form of the disease is presently rare...
  43. ncbi [The success of hygiene in the last 40 years]
    E Thofern
    Hygiene Institut,
    Zentralbl Bakteriol Mikrobiol Hyg B 187:271-94. 1989
    ..There were focuses of typhus, typhoid fever, tuberculosis, diphtheria, scarlet fever, and meningitis...
  44. ncbi Acute bacterial skin infections in pediatric medicine: current issues in presentation and treatment
    James Hedrick
    Physicians to Children and Adolescents, Bardstown, KY 40004, USA
    Paediatr Drugs 5:35-46. 2003
    ..include impetigo, folliculitis, furunculosis, carbuncles, wound infections, abscesses, cellulitis, erysipelas, scarlet fever, acute paronychia, and staphylococcal scalded skin syndrome...
  45. ncbi [Pharmacokinetic and clinical studies of cefteram pivoxil granule in the pediatric field]
    T Motohiro
    Department of Pediatrics, School of Medicine, Kurume University
    Jpn J Antibiot 42:2023-61. 1989
    ..of 142 cases with pharyngitis (22), tonsillitis (12), acute bronchitis (3), pneumonia (11), pleurisy (1), scarlet fever (28), acute purulent otitis media (16), impetigo (13), abscess (2), purulent lymphadenitis (1) and urinary ..
  46. doi Adult Kawasaki's disease with myocarditis, splenomegaly, and highly elevated serum ferritin levels
    Burke A Cunha
    Divisions of Infectious Disease, General Internal Medicine, and Cardiology, Winthrop University Hospital, Mineola, New York 11501, USA
    Heart Lung 39:164-72. 2010
    ..in adults may be mimicked by other acute infections with fever and rash, that is, group A streptococcal scarlet fever, toxic shock syndrome (TSS), and Rocky Mountain Spotted Fever (RMSF)...
  47. ncbi Mobile genetic elements and bacterial toxinoses: the superantigen-encoding pathogenicity islands of Staphylococcus aureus
    Richard P Novick
    Departments of Microbiology and Medicine, Skirball Institute, New York University School of Medicine, New York, NY 10016, USA
    Plasmid 49:93-105. 2003
    ..Examples are the toxins responsible for diphtheria, anthrax, tetanus, botulism, cholera, toxic shock, scarlet fever, exfoliative dermatitis, food poisoning, travelers' diarrhea, shigella dysentery, necrotizing pneumonia, and ..
  48. ncbi [On the development of the infectology service in Novi Sad]
    Grozdana Canak
    Klinika za infektivne bolesti, Klinicki centar Vojvodine, Novi Sad
    Med Pregl 60:625-8. 2007
    ..Other infectious diseases were a serious problem as well: alimentary tract infections, scarlet fever, diphtheria, whooping cough...
  49. ncbi North Atlantic weather oscillation and human infectious diseases in the Czech Republic, 1951-2003
    Zdenek Hubalek
    Medical Zoology Laboratory, Institute of Vertebrate Biology, Academy of Sciences, Brno, Czech Republic
    Eur J Epidemiol 20:263-70. 2005
    ..tested (rubella, mumps, chickenpox, tick-borne encephalitis, Lyme borreliosis, leptospirosis, tularemia and scarlet fever) were uncorrelated with NAO...
  50. doi The pharmaceutical industry and the German National Socialist Regime: I.G. Farben and pharmacological research
    F Lopez-Munoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Clin Pharm Ther 34:67-77. 2009
    ..3582 or Acridine), generally in relation to the treatment of infectious diseases, such as typhus, erysipelas, scarlet fever or paratyphoid diarrhoea. Furthermore, I.G...
  51. ncbi Staphylococcal scalded-skin syndrome in a very low birth weight premature infant
    I R Makhoul
    Department of Neonatology, Rambam Medical Center and Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Pediatrics 108:E16. 2001
    ..diseases such as staphylococcal scalded-skin syndrome (SSSS), bullous impetigo, and staphylococcal scarlet fever may develop. These diseases might cause significant complications and mortality...
  52. ncbi Epidemiology of diseases caused by Streptococcus pyogenes in Serbia during a nine-year period (1991-1999)
    Lazar Ranin
    Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr Subotiaea 1, 11000 Belgrade, Serbia
    Indian J Med Res 119:155-9. 2004
    ..GAS) is an important human pathogen which causes a variety of diseases, including tonsillopharyngitis, scarlet fever and rheumatic fever...
  53. ncbi Evaluation of poststreptococcal illness
    Ricardo G Hahn
    Department of Family Medicine, University of Southern California, Los Angeles, California, USA
    Am Fam Physician 71:1949-54. 2005
    Group A beta-hemolytic streptococcal pharyngitis, scarlet fever, and rarely asymptomatic carrier states are associated with a number of poststreptococcal suppurative and nonsuppurative complications...
  54. ncbi [Serotype and antibiotic susceptibility of isolates from children with group A streptococcal infection; observation for 10 years]
    K Fujita
    Department of Pediatrics, Asahikawa Medical College
    Kansenshogaku Zasshi 68:1229-36. 1994
    ..Four hundred and seventy-nine strains were isolated from patients with pharyngitis, 133 from those with scarlet fever, 35 from those with suppurative infection and 23 from those with non-suppurative disease...
  55. ncbi Kawasaki disease: A brief history
    J C Burns
    Department of Pediatrics, University of California San Diego, La Jolla, California 92093 0830, USA
    Pediatrics 106:E27. 2000
    ..may be part of the spectrum of the same disease and clinically mild KD masqueraded as other diseases, such as scarlet fever in the preantibiotic era...
  56. ncbi [Laboratory and clinical studies on cefteram pivoxil in the field of pediatrics]
    F Hayakawa
    Department of Pediatrics, Anjo Kosei Hospital
    Jpn J Antibiot 42:1849-59. 1989
    ..3. Twenty-six pediatric patients with acute infectious diseases (scarlet fever 3 cases, tonsillitis 7, epiglottitis 1, bronchitis 5, pneumonia 5, urinary tract infection 3, cervical ..
  57. ncbi [Infectious skin diseases in childhood. 1: Bacteria and fungi]
    W Pfutzner
    MMW Stipendiat, Forschungsschwerpunkt Genodermatosen, Klinik u Poliklinik für Dermatologie u Allergologie der LMU München
    MMW Fortschr Med 144:24-8, 30. 2002
    ..Of importance among the bacterial skin diseases in pediatrics are impetigo, scarlet fever, borreliosis and cat-scratch fever...
  58. ncbi Staphylococcal enterotoxins G and I, a cause of severe but reversible neonatal enteropathy
    Sandhia Naik
    Department of Paediatric Gastroenterology, Barts and The London NHS Trust, London, United Kingdom
    Clin Gastroenterol Hepatol 6:251-4. 2008
    ..same S aureus strains (staphylococcal enterotoxin G and staphylococcal enterotoxin I) and are implicated in scarlet fever and toxic shock...
  59. ncbi [The characteristics of staphylococcal enterotoxins produced by strains isolated from mastitic cows, including epidemiological aspects]
    Paweł Nawrotek
    Katedra Immunologii i Mikrobiologii, Wydziału Biotechnologii i Hodowli Zwierzat AR w Szczecinie
    Przegl Epidemiol 59:891-902. 2005
    ..toxins (staphylococcal toxic-shock syndrome toxin--TSST-1, A and B exfoliative toxins and streptococcal scarlet fever toxin). Twenty one serological types of staphylococcal enterotoxins are distinguished...
  60. pmc Diphtheria and hearing loss
    C R Schubert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, 610 N Walnut Street, 460 WARF, Madison, WI 53705, USA
    Public Health Rep 116:362-8. 2001
    ..To determine if infectious diseases usually experienced in childhood have an effect on hearing ability later in life...
  61. ncbi [Molecular characterization of Streptococcus pyogenes from invasive disease and streptococcal toxic shock syndrome episodes]
    F Traverso
    Hospital Ramón Santamarina, Tandil, Argentina
    Rev Argent Microbiol 42:41-5. 2010
    Streptococcus pyogenes causes a variety of common human diseases, including pharyngitis, scarlet fever and impetigo...
  62. pmc Characterization and clonal distribution of four alleles of the speA gene encoding pyrogenic exotoxin A (scarlet fever toxin) in Streptococcus pyogenes
    K Nelson
    Institute of Molecular Evolutionary Genetics, Pennsylvania State University, University Park 16802
    J Exp Med 174:1271-4. 1991
    Streptococcus pyogenes strains producing pyrogenic exotoxin A (scarlet fever toxin) have recently caused episodes of streptococcal toxic-shock-like syndrome (TSLS)...
  63. ncbi Superantigen-induced proliferation of human CD4+CD25- T cells is followed by a switch to a functional regulatory phenotype
    Amanda L Taylor
    Pathogen Host Interaction Group, Division of Clinical Medicine, Brighton and Sussex Medical School, Falmer, United Kingdom
    J Immunol 185:6591-8. 2010
    Bacterial superantigens are potent T cell activators. In humans they cause toxic shock and scarlet fever, and they are implicated in Kawasaki's disease, autoimmunity, atopy, and sepsis...
  64. ncbi [Clinical studies on cefteram pivoxil granules in pediatrics]
    H Sato
    Department of Pediatrics, Tokyo Metropolitan Ebara General Hospital
    Jpn J Antibiot 42:1948-62. 1989
    ..conducted in 40 children including 13 patients of acute tonsillitis, 10 of acute lacunar tonsillitis, 10 of scarlet fever, 2 of acute bronchitis, 2 of pneumonia, and 1 each of pneumonia with enteritis, phlegmon and urinary tract ..
  65. ncbi [Bacteriological, pharmacokinetic and clinical studies on cefteram pivoxil in the pediatric field]
    Y Toyonaga
    Department of Pediatrics, Jikei University School of Medicine
    Jpn J Antibiot 42:1799-814. 1989
    ..pneumonia, 10 cases of bronchitis, 11 cases of tonsillitis, 7 cases of urinary tract infections, 3 cases of scarlet fever and 1 case of otitis media...
  66. ncbi To treat or not to treat? Management of guttate psoriasis and pityriasis rosea in patients with evidence of group A Streptococcal infection
    Karthik Krishnamurthy
    Albert Einstein College of Medicine, Bronx, NY, USA
    J Drugs Dermatol 9:241-50. 2010
    ..role of Streptococcus in the immunopathogenesis of these entities, and the associated risk of development of scarlet fever and poststreptococcal sequelae, are not centrally reported...
  67. ncbi [Clinical studies of cefteram pivoxil in pediatric infection]
    H Hirosawa
    Department of Pediatrics, School of Medicine, Kyorin University
    Jpn J Antibiot 42:1828-36. 1989
    ..acute pharyngitis, 1 with acute nasopharyngitis, 6 with acute tonsillitis, 9 with acute bronchitis, 2 with scarlet fever, 1 with purulent parotitis and 1 with purulent cervical lymphadenitis. 4...
  68. ncbi A screening of streptococci freshly isolated from human and animal sources for binding of human IgG
    K H Schmidt
    Akademie der Wissenschaften der DDR, , Jena
    Zentralbl Bakteriol Mikrobiol Hyg A 265:420-9. 1987
    ..streptococci isolated from suppurating lesions showed an increased IgG uptake when compared with isolates from scarlet fever patients or patients with throat infections...
  69. ncbi [Refugees at Malmö Epidemic Hospital in 1945]
    S Cronberg
    Infektionskliniken,
    Sydsven Medicinhist Sallsk Arsskr 30:151-66. 1993
    ..Other common disorders were diphtheria, scarlet fever, enteric fever and tuberculosis...
  70. doi Isolation and identification of antioxidant compounds from Ligularia fischeri
    Ya Fang Shang
    Natural Product Research Center, KIST Gangneung Inst, Daejeon dong, Gangneung, Gangwon, Republic of Korea
    J Food Sci 75:C530-5. 2010
    ..Nakai, a well-known edible medicinal herb in Korea, has been used to treat maladies such as jaundice, scarlet fever, rheumatoid arthritis, and hepatic function failure...
  71. pmc Infection by Streptococcus pyogenes induces the receptor activator of NF-kappaB ligand expression in mouse osteoblastic cells
    Nobuo Okahashi
    Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, 1 8 Yamadaoka, Japan
    Infect Immun 71:948-55. 2003
    Group A Streptococcus pyogenes is known to induce nongonococcal septic arthritis in addition to pharyngitis, scarlet fever, and poststreptococcal sequelae. However, little is known about the interaction between S. pyogenes and bone cells...
  72. pmc Structure of streptococcal pyrogenic exotoxin A reveals a novel metal cluster
    C A Earhart
    Department of Biochemistry, University of Minnesota Medical School, Minneapolis 55455, USA
    Protein Sci 9:1847-51. 2000
    ..A, B, and C (SPEA, SPEB, and SPEC) are responsible for the fever, rash, and other toxicities associated with scarlet fever and streptococcal toxic shock syndrome...
  73. ncbi [Sanitary conditions, medical care and epidemiology situation of infectious diseases in Lvov in the period of Galicia autonomy (from the years 60ties/70ties of 19th century to the year 1914)]
    Włodzimierz Berner
    Katedra i Zakład Historii Medycyny i Farmacji Uniwersytetu Medycznego w Lodzi
    Przegl Epidemiol 61:815-25. 2007
    ..Among the most dangerous diseases predominated tuberculosis, followed by scarlet fever, diphtheria, measles and whooping cough, typhoid fever and dysentery...
  74. ncbi [Kawasaki's disease with eruptive pustular and guttate psoriasis]
    F Boralevi
    Unité de dermatologie pédiatrique, Hôpital Pellegrin Enfants, Place Amelie Raba Leon, 33076 Bordeaux Cedex
    Ann Dermatol Venereol 130:528-31. 2003
    ..We report a case of psoriasis, first pustular and then guttate, occurring during Kawasaki's disease, and discuss a common pathophysiological mechanism...
  75. ncbi Evidence base of incubation periods, periods of infectiousness and exclusion policies for the control of communicable diseases in schools and preschools
    M Richardson
    Paediatric Infectious Diseases Unit, St George s Hospital, St George s Hospital Medical School, London, UK
    Pediatr Infect Dis J 20:380-91. 2001
    ..We collected the available evidence for a wide range of infections and infestations and produced evidence-based guidelines for their control in schools and preschools...
  76. doi The perfect food and the filth disease: milk-borne typhoid and epidemiological practice in late Victorian Britain
    Jacob Steere-Williams
    Program in the History of Medicine and Allied Sciences, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Hist Med Allied Sci 65:514-45. 2010
    ..route in outbreaks of typhoid fever, these investigations served as a model for later studies of milk-borne scarlet fever, diphtheria, and perhaps tuberculosis...
  77. ncbi [Exanthema as a main symptom in the febrile child]
    C Aebi
    Päidiatrische Infektiologie, Universitatsspital Bern, Inselspital, Bern
    Ther Umsch 62:549-55. 2005
    ..Therapeutic intervention is also necessary in patients with scarlet fever, rheumatic fever, varicella in postpuberal and immunocompromised individuals, in Kawasaki's disease, in Still'..
  78. ncbi The fourth disease, 1900-2000
    M E Weisse
    Department of Pediatrics, West Virginia University School of Medicine, USA
    Lancet 357:299-301. 2001
    Measles and scarlet fever were differentiated from one another in the 17th century. Rubella was accepted as the third distinct paediatric exanthem in 1881...
  79. ncbi Kawasaki disease - an Indian perspective
    Surjit Singh
    Pediatric Allergy and Immunology Unit, Advanced Pediatric Center, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
    Indian Pediatr 46:563-71. 2009
    ..The clinical features of KD can be confused with other common conditions like scarlet fever and the Stevens Johnson syndrome, if the clinician is not careful...
  80. ncbi Group A streptococci in the 1990s
    A Efstratiou
    WHO Collaborating Centre for Diphtheria and Streptococcal Infections, PHLS Respiratory and Systemic Infection Laboratory, Central Public Health Laboratory, London, UK
    J Antimicrob Chemother 45:3-12. 2000
    ..such as the M1 serotype which in earlier decades was primarily seen in cases of either superficial disease or scarlet fever. Population-based surveillance studies have clearly indicated the importance and relevance of type ..
  81. ncbi Sequence and expression of NAPlr is conserved among group A streptococci isolated from patients with acute poststreptococcal glomerulonephritis (APSGN) and non-APSGN
    Masayuki Fujino
    Department of Public Health, National Defense Medical College, Saitama Japan
    J Nephrol 20:364-9. 2007
    ..It would be helpful to determine whether certain GAS strains from APSGN patients specifically express NAPlr and whether strains from non-APSGN patients express lower levels or an altered form of NAPlr...
  82. pmc Crystal structure of a dimeric form of streptococcal pyrogenic exotoxin A (SpeA1)
    Matthew D Baker
    Department of Biology and Biochemistry, Building 4 South, University of Bath, Claverton Down, Bath BA2 7AY, UK
    Protein Sci 13:2285-90. 2004
    Streptococcal pyrogenic exotoxin A (SpeA1) is a bacterial superantigen associated with scarlet fever and streptococcal toxic shock syndrome (STSS)...
  83. ncbi Major childhood infectious diseases and other determinants associated with type 1 diabetes: a case-control study
    M T Tenconi
    Department of Preventive Medicine, University of Pavia, via Forlanini 2, I 27100, Pavia, Italy
    Acta Diabetol 44:14-9. 2007
    ..31; 95%CI 0.11-0.86) and for history of scarlet fever in both sexes and age groups (OR 0.19; 95%CI 0.08-0.46)...
  84. ncbi [Clinical evaluation of cefteram pivoxil fine granules in pediatric infections]
    Y Wagatsuma
    Department of Pediatrics, Sapporo City General Hospital
    Jpn J Antibiot 42:1735-44. 1989
    ..3 cases with bronchitis and in 4 cases with tonsillitis/pharyngitis, excellent in 1 and good in another with scarlet fever, and good in 1 and poor in another with urinary tract infection (UTI) (2) Six cases (4 males, 2 females) with ..
  85. doi Enhanced synthesis and antimicrobial activities of bacteriocins produced by Mexican strains of Bacillus thuringiensis
    N de la Fuente-Salcido
    Departamento de Ingeniería en Alimentos, Universidad de Guanajuato, Instituto de Ciencias Agricolas, Apartado postal 311, 36500 Irapuato, Guanajuato, Mexico
    Arch Microbiol 190:633-40. 2008
    ..and Gram-negative bacteria, including common etiological agents of human diseases, such as strep throat and scarlet fever, septicemia, pneumonia, urinary tract infection, and emetic and gastrointestinal syndromes...
  86. ncbi [A clinical study on cefteram pivoxil granule in the field of pediatrics]
    T Haruta
    Department of Pediatrics, Kobe Central Municipal Hospital
    Jpn J Antibiot 42:2016-22. 1989
    ..patients with tonsillitis or pharyngitis, excellent in all cases of 2 patients with pneumonia, 1 patient with scarlet fever and 1 patient with pyelonephritis, and fair in 1 patient with purulent cervical lymphadenitis...
  87. ncbi Staphylococcus aureus as a cause of perianal dermatitis
    A D Montemarano
    Dermatology Service, Walter Reed Army Medical Center, Washington, D.C. 20307-5001
    Pediatr Dermatol 10:259-62. 1993
    ..aureus is the true cause. Other streptococcal and staphylococcal cutaneous infections may exhibit overlapping clinical features, including scarlet fever, impetigo, toxic shock syndrome, and cellulitis.
  88. pmc Epidemiologic maps of Washington DC, 1878-1909
    D Vecchioli
    History of Medicine Division, National Library of Medicine, Bethesda, MD 20894, USA
    Public Health Rep 111:314-9. 1996
    ..when the Health Officers themselves were coming to grips with the causes of diseases that included diphtheria, scarlet fever, typhoid and malarial fevers, smallpox, consumption (tuberculosis), and diarrheal diseases...
  89. pmc Seasonality and comparative dynamics of six childhood infections in pre-vaccination Copenhagen
    C Jessica E Metcalf
    Centre for Infectious Disease Dynamics, The Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA
    Proc Biol Sci 276:4111-8. 2009
    ..For the three bacterial infections, pertussis, scarlet fever and diphtheria, there is additionally a strong increase in transmission during the late summer before the end ..
  90. ncbi [Laboratory and clinical studies of cefteram pivoxil in pediatric field]
    T Nishimura
    Department of Pediatrics, Osaka Medical College
    Jpn J Antibiot 42:2004-15. 1989
    ..cases of pediatric bacterial infections including 20 cases of tonsillitis, 3 cases of bronchitis, 6 cases of scarlet fever, 3 cases of UTI and 1 case each of bronchopneumonia, abscess, staphylococcal scalded skin syndrome and ..
  91. ncbi Outbreak of scarlet fever associated with emm12 type group A Streptococcus in 2011 in Shanghai, China
    Mingliang Chen
    Department of Infectious Diseases, Children s Hospital of Fudan University, 399 Wanyuan Road, Shanghai 201102, China
    Pediatr Infect Dis J 31:e158-62. 2012
    An unprecedented, large outbreak of childhood scarlet fever occurred in Shanghai between April and July 2011. Investigation of the epidemiology could enhance our understanding of the factors related to the outbreak.
  92. ncbi Scarlet fever in Poland in 2011
    Mirosław P Czarkowski
    Department of Epidemiology National Institute of Public Health National Institute of Hygiene, Warsaw, Poland
    Przegl Epidemiol 67:203-6, 323-5. 2013
    Assessment of the epidemiological situation of scarlet fever in Poland in 2011 MATERIALS AND MATHODS: The evaluation was performed by analysing the data published in the bulletin, "Infectious diseases and poisonings in Poland in 2011" (..
  93. ncbi [A wavelet analysis on the onset cycle of scarlet fever in Beijing and its relationship with theory of five evolutive phases and six climatic factors]
    Bang ze Fu
    Juan School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China
    Zhongguo Zhong Xi Yi Jie He Za Zhi 33:338-42. 2013
    To explore the onset cycle of scarlet fever in Beijing and its association with theory of five evolutive phases and six climatic factors (FEPSCF).
  94. doi Evaluation of a streptococcal pharyngitis score in southern Taiwan
    Ching Tang Shih
    Department of Family Medicine, Fooyin University Hospital, Pingtung, Taiwan
    Pediatr neonatol 53:49-54. 2012
    ..We evaluated the validity of the McIsaac sore throat score in Southern Taiwan and compared our findings to those of other studies...
  95. ncbi A multicentric, open label, randomised, postmarketing efficacy study comparing multidose of lincomycin hydrochloride capsule 500 mg with multidose cefpodoxime proxetil tablet 200 mg in patients with tonsillitis, sinusitis
    Ajay Kothadiya
    KEM Hospital, Pune 411011
    J Indian Med Assoc 110:580-3. 2012
    ..The study suggests that lincomycin hydrochloride capsules, a conventional antibiotic indicates effective treatment for relief from tonsillitis and sinusitis, as compared to new third generation antibiotic...
  96. ncbi The death of Wolfgang Amadeus Mozart: an epidemiologic perspective
    Richard H C Zegers
    Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Ann Intern Med 151:274-8, W96-7. 2009
    ..b>Scarlet fever, which represents the same underlying disease from an etiologic perspective, is a less likely possibility.
  97. ncbi [Antimicrobial sensitivity and characterization of Streptococcus pyogenes strains isoleated from a scarlatina outbreak]
    Alberto González Pedraza-Avilés
    Centro de Salud, Doctor José Castro Villagrana, Servicios de Salud Pública del Distrito Federal, Mexico, D F, Mexico
    Salud Publica Mex 44:437-41. 2002
    ..To evaluate the in vitro activities of 13 antimicrobial agents against 47 group A Streptococcus pyogenes (GAS) strains, and to determine the presence of genes encoding streptococcal pyrogenic exotoxin A (SpeA) and the M-protein serotypes...
  98. doi [Scarlet fever epidemic during year 1929 in Chile]
    Enrique Laval R
    Programa de Estudios Médicos Humanísticos, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Rev Chilena Infectol 26:168-72. 2009
    b>Scarlet fever is endemic in Chile, with relatively low morbidity and periodic exacerbations every 4 or 5 years, which can become epidemics...
  99. pmc Gene transcript abundance profiles distinguish Kawasaki disease from adenovirus infection
    Stephen J Popper
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Infect Dis 200:657-66. 2009
    ..As a result, diagnosis and critical therapies may be delayed...
  100. ncbi [Epidemiological characteristics of Lyme-like disease in children]
    Saulo Duarte Passos
    Depto de Pediatria, Faculdade de Medicina de Jundiai, SP
    Rev Assoc Med Bras 55:139-44. 2009
    ..which were negative for other pathogens (Parvovirus B19 Human, Herpesvirus 6 Human, Measles, Rubella, Dengue, Scarlet fever and Enterovirus), were tested for borreliosis by Enzyme-Linked Immunosorbent Assay and Western-blotting...
  101. ncbi [Tonsillitis and scarlatiniform rash]
    E Bernal Vañó
    Equipo de Atención Primaria, Sigüenza, Guadalajara, Spain
    An Esp Pediatr 57:387-8. 2002

Research Grants62

  1. CYTOLYSIN-MEDIATED TRANSLOCATION IN S. PYOGENES VIRULENC
    Michael G Caparon; Fiscal Year: 2010
    ..is produced by Streptococcus pyogenes, an important cause of pharyngitis and other serious diseases including scarlet fever, rheumatic fever and necrotizing faciitis...
  2. PROPERTIES OF STREPTOCOCCAL M PROTEIN
    Vincent A Fischetti; Fiscal Year: 2010
    ..Group A streptococcal-associated disease (pharyngitis, rheumatic fever, necrotizing fasciitis, impetigo, and scarlet fever, to name a few) affects millions of people, particularly children, worldwide...
  3. PROPERTIES OF STREPTOCOCCAL M PROTEIN
    Vincent Fischetti; Fiscal Year: 2009
    ..Group A streptococcal-associated disease (pharyngitis, rheumatic fever, necrotizing fasciitis, impetigo, and scarlet fever, to name a few) affects millions of people, particularly children, worldwide...
  4. Heme Acquisition in Group A Streptococcus
    Benfang Lei; Fiscal Year: 2005
    ..referred as Group A Streptococcus (GAS), is an important human pathogen causing pharyngitis, cellulitis, scarlet fever, necrotizing fasciitis, toxic shock syndrome, acute rheumatic fever, rheumatic heart disease, and ..
  5. Heme Acquisition in Group A Streptococcus
    Benfang Lei; Fiscal Year: 2004
    ..referred as Group A Streptococcus (GAS), is an important human pathogen causing pharyngitis, cellulitis, scarlet fever, necrotizing fasciitis, toxic shock syndrome, acute rheumatic fever, rheumatic heart disease, and ..
  6. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2006
    ..a) to evaluate the role of pyrogenic toxin superantigens, notably streptococcal pyrogenic exotoxins (SPEs, scarlet fever toxins, in causing both acute toxic shock syndrome and vascular illnesses and chronic autoimmune and allergic ..
  7. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2002
    ..a) to evaluate the role of pyrogenic toxin superantigens, notably streptococcal pyrogenic exotoxins (SPEs, scarlet fever toxins, in causing both acute toxic shock syndrome and vascular illnesses and chronic autoimmune and allergic ..
  8. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2004
    ..a) to evaluate the role of pyrogenic toxin superantigens, notably streptococcal pyrogenic exotoxins (SPEs, scarlet fever toxins, in causing both acute toxic shock syndrome and vascular illnesses and chronic autoimmune and allergic ..
  9. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2003
    ..a) to evaluate the role of pyrogenic toxin superantigens, notably streptococcal pyrogenic exotoxins (SPEs, scarlet fever toxins, in causing both acute toxic shock syndrome and vascular illnesses and chronic autoimmune and allergic ..
  10. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2005
    ..a) to evaluate the role of pyrogenic toxin superantigens, notably streptococcal pyrogenic exotoxins (SPEs, scarlet fever toxins, in causing both acute toxic shock syndrome and vascular illnesses and chronic autoimmune and allergic ..
  11. STREPTOCOCCUS PYOGENES--CLONAL ANALYSIS OF VIRULENCE
    JAMES MUSSER; Fiscal Year: 1992
    ..and other disease syndromes such as pharyngitis, glomerulonephritis, cellulitis, rheumatic fever, and scarlet fever. The second goal is to determine if pyrogenic exotoxin-expressing strains (especially those producing serotype ..
  12. DETERMINANTS OF VIRULENCE IN GROUP A STREPTOCOCCI
    JOSEPH FERRETTI; Fiscal Year: 1990
    ..g., acute glomerulonephrintis, rheumatic fever, or scarlet fever. 2. Elucidate the study further the mechanism of toxigenic conversion by whihc lysogenic strains of S...
  13. DETERMINANTS OF VIRULENCE IN GROUP A STREPTOCOCCI
    JOSEPH FERRETTI; Fiscal Year: 1991
    ..g., acute glomerulonephrintis, rheumatic fever, or scarlet fever. 2. Elucidate the study further the mechanism of toxigenic conversion by whihc lysogenic strains of S...
  14. MOLECULAR BASIS OF IMMUNE FUNCTION IN HEALTH AND DISEASE
    Raif Geha; Fiscal Year: 1991
    ..bacterial enterotoxins which are implicated in many diseases including toxic shock syndrome, food poisoning, scarlet fever, and possibly autoimmune diseases. The construction of MHC Class II deficient mice (project #5, L...
  15. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 2000
    ..a) to evaluate the role of pyrogenic toxin superantigens, notably streptococcal pyrogenic exotoxins (SPEs, scarlet fever toxins), in causing both acute toxic shock syndrome and vascular illnesses and chronic autoimmune and allergic ..
  16. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXINS
    Patrick Schlievert; Fiscal Year: 1999
    ..a) to evaluate the role of pyrogenic toxin superantigens, notably streptococcal pyrogenic exotoxins (SPEs, scarlet fever toxins), in causing both acute toxic shock syndrome and vascular illnesses and chronic autoimmune and allergic ..
  17. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXIN
    Patrick Schlievert; Fiscal Year: 1991
    ..The SPEs have the capacity to cause scarlet fever, a toxic-shock syndrome-like illness, and may contribute to the early events in development of rheumatic fever,..
  18. CARDIOTOXICITY OF STREPTOCOCCAL PYROGENIC EXOTOXIN
    Patrick Schlievert; Fiscal Year: 1990
    ..The SPEs have the capacity to cause scarlet fever, a toxic-shock syndrome-like illness, and may contribute to the early events in development of rheumatic fever,..
  19. Genetic influences and T-cell activation in Kawasaki Disease
    Jane Burns; Fiscal Year: 2008
    ..This proposal seeks to understand how patient genetics shapes the immune response during the acute phase. These studies may lead to new treatments that will prevent heart damage. ..
  20. Matrix Metalloproteinases in Kawasaki Disease
    Jane Burns; Fiscal Year: 2007
    ..This K24 award will allow the PI to relinquish administrative responsibilities and to share clinical responsibilities with the fellows to allow more time for mentoring activities. ..
  21. Genetic Markers and gene expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2007
    ..This project will build on previous work to understand the genetic basis for susceptibility to KD and its complications, which will lead to new insights into therapeutics and disease prevention. ..
  22. Molecular biology of TSST-1 and other superantigen toxins
    Richard P Novick; Fiscal Year: 2010
    ..By understanding the biology of these gene transfer systems, it is our hope to be able to control staphylococcal gene transfer and so reduce the danger of staphylococcal disease. ..
  23. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2007
    ..Agr group-specific biotypes will be delineated to identify group-specific traits that may be correlated with pathogenic behavior - site and type of lesion, level of virulence, antibiotic resistance, etc.. [unreadable] [unreadable]..
  24. Peptide autoinducers of staphylococcal pathogenicity.
    Richard P Novick; Fiscal Year: 2011
    ....
  25. Genetic Markers and gene expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2006
    ..This project will build on previous work to understand the genetic basis for susceptibility to KD and its complications, which will lead to new insights into therapeutics and disease prevention. ..
  26. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard P Novick; Fiscal Year: 2010
    ....
  27. Genetic Markers and gene expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2008
    ..This project will build on previous work to understand the genetic basis for susceptibility to KD and its complications, which will lead to new insights into therapeutics and disease prevention. ..
  28. Matrix Metalloproteinases in Kawasaki Disease
    Jane Burns; Fiscal Year: 2008
    ..This K24 award will allow the PI to relinquish administrative responsibilities and to share clinical responsibilities with the fellows to allow more time for mentoring activities. ..
  29. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 2008
    ....
  30. Genetic Markers and gene expression in Kawasaki Disease
    Jane C Burns; Fiscal Year: 2010
    ..This project will build on previous work to understand the genetic basis for susceptibility to KD and its complications, which will lead to new insights into therapeutics and disease prevention. ..
  31. Genetic Markers and gene expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2007
    ..This project will build on previous work to understand the genetic basis for susceptibility to KD and its complications, which will lead to new insights into therapeutics and disease prevention. ..
  32. Phase III infliximab for primary treatment of Kawasaki disease IND 11046 6/27/200
    Jane Burns; Fiscal Year: 2008
    ..FDA funding is essential to carry out this study as too few patients in the U.S. would benefit from this therapy to make this new indication economically attractive to the manufacturer (Centocor). [unreadable] [unreadable] [unreadable]..
  33. Genetic Markers and gene expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2009
    ..This project will build on previous work to understand the genetic basis for susceptibility to KD and its complications, which will lead to new insights into therapeutics and disease prevention. ..
  34. Phase III infliximab for primary treatment of Kawasaki disease IND 11046 6/27/200
    Jane C Burns; Fiscal Year: 2010
    ..FDA funding is essential to carry out this study as too few patients in the U.S. would benefit from this therapy to make this new indication economically attractive to the manufacturer (Centocor). ..
  35. Molecular biology of TSST-1 and other superantigen toxins
    Richard Novick; Fiscal Year: 2009
    ..By understanding the biology of these gene transfer systems, it is our hope to be able to control staphylococcal gene transfer and so reduce the danger of staphylococcal disease. ..
  36. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 2009
    ....
  37. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2006
    ..Agr group-specific biotypes will be delineated to identify group-specific traits that may be correlated with pathogenic behavior - site and type of lesion, level of virulence, antibiotic resistance, etc.. [unreadable] [unreadable]..
  38. 8th International Kawasaki Disease Symposium
    Jane Burns; Fiscal Year: 2005
    ....
  39. Genetic Influences & Gene Expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2002
    ..The role that genetic polymorphisms play in these gene expression patterns and their influence on disease susceptibility, response to therapy, and outcome will also be examined. ..
  40. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2001
    ..Mutants will also be tested in these models to determine the importance of the autoinduction system, and an attempt will be made to detect expression of agr genes in the animal. ..
  41. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 2001
    ..In Aim 4, a continuation of a study in which we have identified an autoinducer of streptococcal erythogenic toxin (SPEA) synthesis, is proposed. ..
  42. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2000
    ..Mutants will also be tested in these models to determine the importance of the autoinduction system, and an attempt will be made to detect expression of agr genes in the animal. ..
  43. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 1999
    ..Mutants will also be tested in these models to determine the importance of the autoinduction system, and an attempt will be made to detect expression of agr genes in the animal. ..
  44. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 1999
    ..We have discovered an external activator and an external inhibitor of the response and studies are proposed to test these for possible therapeutic use in staphylococcal disease. ..
  45. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 2002
    ..In Aim 4, a continuation of a study in which we have identified an autoinducer of streptococcal erythogenic toxin (SPEA) synthesis, is proposed. ..
  46. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2002
    ..Mutants will also be tested in these models to determine the importance of the autoinduction system, and an attempt will be made to detect expression of agr genes in the animal. ..
  47. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 2005
    ..In Aim 4, a continuation of a study in which we have identified an autoinducer of streptococcal erythogenic toxin (SPEA) synthesis, is proposed. ..
  48. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2005
    ..Agr group-specific biotypes will be delineated to identify group-specific traits that may be correlated with pathogenic behavior - site and type of lesion, level of virulence, antibiotic resistance, etc.. ..
  49. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2004
    ..Agr group-specific biotypes will be delineated to identify group-specific traits that may be correlated with pathogenic behavior - site and type of lesion, level of virulence, antibiotic resistance, etc.. ..
  50. PEPTIDE AUTOINDUCERS OF STAPHYLOCOCCAL PATHOGENICITY
    Richard Novick; Fiscal Year: 2003
    ..Agr group-specific biotypes will be delineated to identify group-specific traits that may be correlated with pathogenic behavior - site and type of lesion, level of virulence, antibiotic resistance, etc.. ..
  51. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 2004
    ..In Aim 4, a continuation of a study in which we have identified an autoinducer of streptococcal erythogenic toxin (SPEA) synthesis, is proposed. ..
  52. Genetic Influences & Gene Expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2004
    ..The role that genetic polymorphisms play in these gene expression patterns and their influence on disease susceptibility, response to therapy, and outcome will also be examined. ..
  53. MOLECULAR GENETICS OF EXOTOXIN REGULATION IN S AUREUS
    Richard Novick; Fiscal Year: 2003
    ..In Aim 4, a continuation of a study in which we have identified an autoinducer of streptococcal erythogenic toxin (SPEA) synthesis, is proposed. ..
  54. Genetic Influences & Gene Expression in Kawasaki Disease
    Jane Burns; Fiscal Year: 2003
    ..The role that genetic polymorphisms play in these gene expression patterns and their influence on disease susceptibility, response to therapy, and outcome will also be examined. ..