campylobacter infections

Summary

Summary: Infections with bacteria of the genus CAMPYLOBACTER.

Top Publications

  1. pmc Prevalence of Campylobacter, Arcobacter, Helicobacter, and Sutterella spp. in human fecal samples as estimated by a reevaluation of isolation methods for Campylobacters
    J Engberg
    Department of Gastrointestinal Infections, Division of Diagnostics, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    J Clin Microbiol 38:286-91. 2000
  2. ncbi Campylobacter concisus: an evaluation of certain phenotypic and genotypic characteristics
    J Engberg
    Unit of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, Denmark
    Clin Microbiol Infect 11:288-95. 2005
  3. doi Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control study
    Y Doorduyn
    Epidemiology and Surveillance Unit, Netherlands Centre for Infectious Disease Control, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Epidemiol Infect 138:1391-404. 2010
  4. pmc L-fucose utilization provides Campylobacter jejuni with a competitive advantage
    Martin Stahl
    Department of Biochemistry, Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada
    Proc Natl Acad Sci U S A 108:7194-9. 2011
  5. ncbi Characterization of a haemolytic phospholipase A(2) activity in clinical isolates of Campylobacter concisus
    Taghrid S Istivan
    Department of Biotechnology and Environmental Biology, RMIT University, PO Box 71, Bundoora, Victoria 3083, Australia
    J Med Microbiol 53:483-93. 2004
  6. ncbi Prevalence of Campylobacter concisus in diarrhoea of immunocompromised patients
    Rune Aabenhus
    Department of Infectious Diseases, National University Hospital, Copenhagen, Denmark
    Scand J Infect Dis 34:248-52. 2002
  7. pmc MUC1 cell surface mucin is a critical element of the mucosal barrier to infection
    Julie L McAuley
    Mucosal Diseases Program, Mater Medical Research Institute and The University of Queensland, South Brisbane, Queensland, Australia
    J Clin Invest 117:2313-24. 2007
  8. pmc Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunity
    Stefan Bereswill
    Department of Microbiology and Hygiene, Charite University Medicine Berlin, Berlin, Germany
    PLoS ONE 6:e20953. 2011
  9. doi Enteric Salmonella or Campylobacter infections and the risk of inflammatory bowel disease
    Tine Jess
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen S, Denmark
    Gut 60:318-24. 2011
  10. pmc Detection and isolation of Campylobacter species other than C. jejuni from children with Crohn's disease
    Li Zhang
    School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia
    J Clin Microbiol 47:453-5. 2009

Detail Information

Publications262 found, 100 shown here

  1. pmc Prevalence of Campylobacter, Arcobacter, Helicobacter, and Sutterella spp. in human fecal samples as estimated by a reevaluation of isolation methods for Campylobacters
    J Engberg
    Department of Gastrointestinal Infections, Division of Diagnostics, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    J Clin Microbiol 38:286-91. 2000
    ..Further investigations to establish the role of C. concisus and S. wadsworthensis in enteric disease is needed. We conclude that a range of campylobacteria may cause infections in Denmark...
  2. ncbi Campylobacter concisus: an evaluation of certain phenotypic and genotypic characteristics
    J Engberg
    Unit of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, Denmark
    Clin Microbiol Infect 11:288-95. 2005
    ..Further evidence is needed to support the possible role of C. concisus as a human enteric pathogen...
  3. doi Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control study
    Y Doorduyn
    Epidemiology and Surveillance Unit, Netherlands Centre for Infectious Disease Control, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Epidemiol Infect 138:1391-404. 2010
    ..jejuni infections. This study illustrates that important differences in risk factors exist for different Campylobacter spp. and these may differ dependent on age, season or degree of urbanization...
  4. pmc L-fucose utilization provides Campylobacter jejuni with a competitive advantage
    Martin Stahl
    Department of Biochemistry, Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada
    Proc Natl Acad Sci U S A 108:7194-9. 2011
    ..This identifies a previously unrecorded metabolic pathway in select strains of C. jejuni associated with a virulent lifestyle...
  5. ncbi Characterization of a haemolytic phospholipase A(2) activity in clinical isolates of Campylobacter concisus
    Taghrid S Istivan
    Department of Biotechnology and Environmental Biology, RMIT University, PO Box 71, Bundoora, Victoria 3083, Australia
    J Med Microbiol 53:483-93. 2004
    ..concisus. The detection of haemolytic PLA(2) activity in C. concisus indicates the presence of a potential virulence factor in this species and supports the hypothesis that C. concisus is a possible opportunistic pathogen...
  6. ncbi Prevalence of Campylobacter concisus in diarrhoea of immunocompromised patients
    Rune Aabenhus
    Department of Infectious Diseases, National University Hospital, Copenhagen, Denmark
    Scand J Infect Dis 34:248-52. 2002
    ..C. concisus may be a frequent cause of diarrhoea in immunocompromised patients. Two groups of C. concisus were found and these groups possibly vary in their pathogenic potential...
  7. pmc MUC1 cell surface mucin is a critical element of the mucosal barrier to infection
    Julie L McAuley
    Mucosal Diseases Program, Mater Medical Research Institute and The University of Queensland, South Brisbane, Queensland, Australia
    J Clin Invest 117:2313-24. 2007
    ....
  8. pmc Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunity
    Stefan Bereswill
    Department of Microbiology and Hygiene, Charite University Medicine Berlin, Berlin, Germany
    PLoS ONE 6:e20953. 2011
    ..Detailed investigation of C. jejuni-mediated intestinal immunopathology is hampered by the lack of appropriate vertebrate models. In particular, mice display colonization resistance against this pathogen...
  9. doi Enteric Salmonella or Campylobacter infections and the risk of inflammatory bowel disease
    Tine Jess
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen S, Denmark
    Gut 60:318-24. 2011
    ....
  10. pmc Detection and isolation of Campylobacter species other than C. jejuni from children with Crohn's disease
    Li Zhang
    School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia
    J Clin Microbiol 47:453-5. 2009
    ..concisus and higher levels of antibodies to C. concisus were detected in children with Crohn's disease (CD) than in controls. Campylobacter species other than C. jejuni were isolated from intestinal biopsy specimens of children with CD...
  11. pmc Campylobacter genotyping to determine the source of human infection
    Samuel K Sheppard
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Clin Infect Dis 48:1072-8. 2009
    ....
  12. pmc Host association of Campylobacter genotypes transcends geographic variation
    Samuel K Sheppard
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Appl Environ Microbiol 76:5269-77. 2010
    ..These findings are consistent with local and international transmission of host-associated lineages among food animal species and provide a foundation for further improvements in genetic attribution...
  13. doi Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization
    Dirk Hofreuter
    Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA
    Cell Host Microbe 4:425-33. 2008
    ..In addition, these studies revealed remarkably specific nutritional requirements for a pathogen to effectively colonize different tissues...
  14. pmc Epidermal growth factor inhibits Campylobacter jejuni-induced claudin-4 disruption, loss of epithelial barrier function, and Escherichia coli translocation
    Jennifer M Lamb-Rosteski
    Department of Biological Sciences, Inflammation Research Network, University of Calgary, 2500 University Dr N W, Calgary, Alberta T2N 1N4, Canada
    Infect Immun 76:3390-8. 2008
    ..These findings highlight EGF's ability to alter colonization of C. jejuni in the intestinal tract and to protect against pathogen-induced barrier defects...
  15. pmc Detection of Campylobacter concisus and other Campylobacter species in colonic biopsies from adults with ulcerative colitis
    Indrani Mukhopadhya
    Gastrointestinal Research Group, Division of Applied Medicine, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom
    PLoS ONE 6:e21490. 2011
    ..This study investigated the prevalence of Campylobacter species in colonic biopsy samples from adults with UC and healthy controls...
  16. doi The clinical importance of emerging Campylobacter species
    Si Ming Man
    Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK
    Nat Rev Gastroenterol Hepatol 8:669-85. 2011
    ..This Review presents the latest information on the role and clinical importance of emerging Campylobacter spp. in gastrointestinal health and disease...
  17. pmc Comparison of molecular typing methods useful for detecting clusters of Campylobacter jejuni and C. coli isolates through routine surveillance
    Clifford G Clark
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    J Clin Microbiol 50:798-809. 2012
    ..Similarly, comparing several different typing methods reveals a great deal about differences in how the methods group individuals within the population...
  18. ncbi Campylobacter concisus and other Campylobacter species in children with newly diagnosed Crohn's disease
    Si Ming Man
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia
    Inflamm Bowel Dis 16:1008-16. 2010
    ..To further investigate this issue we determined the prevalence of these organisms in pediatric patients newly diagnosed with CD...
  19. ncbi Correlation between invasion of Caco-2 eukaryotic cells and colonization ability in the chick gut in Campylobacter jejuni
    I Hanel
    Federal Research Centre for Virus Diseases of Animals, Institute of Molecular Pathogenesis, Jena, Naumburger Str 96a, 07743 Jena, Germany
    Vet Microbiol 101:75-82. 2004
    ..The characterization of the flagellin gene of the used C. jejuni strains resulted in eight flaA types. There was no association between flaA type and invasion or colonization ability in the chick gut...
  20. ncbi The health burden of Campylobacter infection and the impact of antimicrobial resistance: playing chicken
    Guillermo M Ruiz-Palacios
    Clin Infect Dis 44:701-3. 2007
  21. doi Molecular and spatial epidemiology of human campylobacteriosis: source association and genotype-related risk factors
    P Mullner
    Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand
    Epidemiol Infect 138:1372-83. 2010
    ..In particular young children in rural areas had a higher risk of infection with ruminant strains than their urban counterparts. These findings provide important information for the implementation of pathway-specific control strategies...
  22. pmc Antibiotic resistance in Campylobacter: emergence, transmission and persistence
    Taradon Luangtongkum
    Department of Veterinary Microbiology and Preventive Medicine, 1116 Veterinary Medicine Complex, Iowa State University, Ames, IA 500111, USA
    Future Microbiol 4:189-200. 2009
    ..A future perspective on antibiotic resistance and potential approaches for the control of antibiotic-resistant Campylobacter, will also be discussed...
  23. ncbi Campylobacter sugars sticking out
    Patricia Guerry
    Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Trends Microbiol 16:428-35. 2008
    ..The exciting surge in recent research activities will be summarized in this review...
  24. ncbi Campylobacter jejuni: molecular biology and pathogenesis
    Kathryn T Young
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nat Rev Microbiol 5:665-79. 2007
    ..Comparing the different host responses to C. jejuni colonization should increase our understanding of this organism...
  25. ncbi Climate variability and campylobacter infection: an international study
    R Sari Kovats
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Int J Biometeorol 49:207-14. 2005
    ..The main driver of seasonality of campylobacter remains elusive and underscores the need to identify the major serotypes and routes of transmission for this disease...
  26. ncbi Assigning the source of human campylobacteriosis in New Zealand: a comparative genetic and epidemiological approach
    Petra Mullner
    Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand
    Infect Genet Evol 9:1311-9. 2009
    ..The comparative-modeling and molecular sentinel surveillance approach proposed in this study provides new opportunities for the management of zoonotic diseases...
  27. ncbi Campylobacter jejuni: a brief overview on pathogenicity-associated factors and disease-mediating mechanisms
    Javid I Dasti
    Institute of Medical Microbiology, University Medical Centre Göttingen, Kreuzbergring 57, D 37075 Gottingen, Germany
    Int J Med Microbiol 300:205-11. 2010
    ..Indeed, several lines of evidence suggest exploitation of different adaptation strategies by this pathogen depending on its requirement, whether to establish itself in the natural avian reservoir or during the course of human infection...
  28. ncbi The epidemiology of antibiotic resistance in Campylobacter
    John E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
    Microbes Infect 8:1955-66. 2006
    ....
  29. pmc Activation of human and chicken toll-like receptors by Campylobacter spp
    Marcel R de Zoete
    Department of Infectious Diseases and Immunology, Utrecht University, P O Box 80 165, 3508 TD Utrecht, The Netherlands
    Infect Immun 78:1229-38. 2010
    ..The results suggest that differences in bacterial cell wall integrity and in TLR responses to Campylobacter LOS and/or DNA may contribute to the distinct clinical manifestation between the species...
  30. pmc Wide geographical distribution of internationally rare Campylobacter clones within New Zealand
    S M McTavish
    ESR Ltd, Kenepuru Science Centre, Porirua, New Zealand
    Epidemiol Infect 136:1244-52. 2008
    ....
  31. pmc Host-pathogen interactions in Campylobacter infections: the host perspective
    Riny Janssen
    Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Clin Microbiol Rev 21:505-18. 2008
    ..Such studies combined with better integration of host and pathogen research driven by epidemiological findings may truly advance our understanding of Campylobacter infection in humans...
  32. doi A role for Campylobacter jejuni-induced enteritis in inflammatory bowel disease?
    Lisa D Kalischuk
    Agriculture and Agri Food Canada, Lethbridge, Canada
    Am J Physiol Gastrointest Liver Physiol 298:G1-9. 2010
    ....
  33. ncbi Campylobacter jejuni Infections: update on emerging issues and trends
    B M Allos
    Department of Preventive Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Clin Infect Dis 32:1201-6. 2001
    ..jejuni infection, but its incidence is <1 per 1000 infections. Careful food preparation and cooking practices may prevent some Campylobacter infections.
  34. ncbi Campylobacter, from obscurity to celebrity
    J P Butzler
    Department of Human Ecology, Faculty of Medicine, Vrije Universiteit Brussel, Brussels, Belgium
    Clin Microbiol Infect 10:868-76. 2004
    ..jejuni remains susceptible to fluoroquinolones. The public health burden of Campylobacter spp. other than C. jejuni/C. coli remains unmeasured. Better diagnostic methods may reveal the true health burden of these organisms...
  35. ncbi Changes in causes of acute gastroenteritis in the United Kingdom over 15 years: microbiologic findings from 2 prospective, population-based studies of infectious intestinal disease
    Clarence C Tam
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
    Clin Infect Dis 54:1275-86. 2012
    ..We examined changes in etiology and diagnostic yield of IID cases over 15 years...
  36. doi Caecal transcriptome analysis of colonized and non-colonized chickens within two genetic lines that differ in caecal colonization by Campylobacter jejuni
    X Y Li
    Department of Poultry Science, Texas A and M University, College Station, TX 77843, USA
    Anim Genet 42:491-500. 2011
    ..jejuni colonization and that the tumour necrosis factor receptor superfamily genes play important roles in determining C. jejuni non-colonization in broilers...
  37. pmc The dioxin crisis as experiment to determine poultry-related campylobacter enteritis
    Akke Vellinga
    Department of Epidemiology and Social Medicine, Institute of Public Health Louis Pasteur, Brussels, Belgium
    Emerg Infect Dis 8:19-22. 2002
    ..Through the sentinel surveillance system, a decrease in Campylobacter infections during June 1999 was noticed...
  38. doi Molecular-based detection of non-culturable and emerging campylobacteria in patients presenting with gastroenteritis
    S Bullman
    Department of Biological Sciences, Cork Institute of Technology, Ireland
    Epidemiol Infect 140:684-8. 2012
    ..are responsible for a considerable proportion of human enteritis and the true incidence of infection is likely to be significantly underestimated where conventional Campylobacter culture methods are used in isolation...
  39. pmc Allelic diversity and recombination in Campylobacter jejuni
    S Suerbaum
    Institut fur Hygiene und Mikrobiologie der Universitat Wurzburg, D 97080 Wurzburg, Germany
    J Bacteriol 183:2553-9. 2001
    ..These analyses showed that intraspecific recombination is frequent in C. jejuni and has generated extensive diversity of allelic profiles from a small number of polymorphic nucleotides...
  40. pmc Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases
    Y Doorduyn
    Department Epidemiology and Surveillance, Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Epidemiol Infect 136:1225-34. 2008
    We studied the role of host genetics in the susceptibility to severe Salmonella and Campylobacter infections and chronic sequelae of these infections...
  41. pmc Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasion
    Joshua A Fields
    Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1459 Laney Walker Blvd, Augusta, GA 30912, USA
    J Bacteriol 190:3411-6. 2008
    ..CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis...
  42. ncbi Isolation of motile and non-motile insertional mutants of Campylobacter jejuni: the role of motility in adherence and invasion of eukaryotic cells
    R Yao
    Enteric Diseases Program, Naval Medical Research Institute Annex, Rockville, Maryland 20852
    Mol Microbiol 14:883-93. 1994
    ..Characterization of the mutants at the molecular level and in animal models should further contribute to our understanding of the pathogenicity of these organisms...
  43. pmc Influence of season and geography on Campylobacter jejuni and C. coli subtypes in housed broiler flocks reared in Great Britain
    F Jorgensen
    Health Protection Agency, Microbiology Services, Food, Water and Environmental Microbiology Network, Porton Down, Salisbury SP4 0JG, United Kingdom
    Appl Environ Microbiol 77:3741-8. 2011
    ..Flocks slaughtered at the same time were more likely to have similar complexes, and ST-45 had a seasonal pattern, with the highest prevalence in June, and was also more likely to be present in flocks reared in northern Great Britain...
  44. doi Campylobacter colonization of the chicken induces a proinflammatory response in mucosal tissues
    Christopher K Smith
    Institute for Animal Health, Compton, Berkshire, UK
    FEMS Immunol Med Microbiol 54:114-21. 2008
    ..This correlated with an influx of heterophils but was not associated with any pathology. These results suggest that in poultry there may be a controlled inflammatory process during colonization...
  45. ncbi Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter spp
    Sophie Payot
    Institut National de la Recherche Agronomique, UR086 BioAgresseurs, santé, Environnement, Nouzilly, France
    Microbes Infect 8:1967-71. 2006
    The incidence of human Campylobacter infections is increasing worldwide, as well as the proportion of isolates resistant to fluoroquinolones and/or macrolides, the drugs of choice to treat campylobacteriosis...
  46. doi A re-evaluation of the impact of temperature and climate change on foodborne illness
    I R Lake
    School of Environmental Sciences, University of East Anglia, Norwich, UK
    Epidemiol Infect 137:1538-47. 2009
    ..These adaptations to temperature imply that current estimates of how climate change may alter foodborne illness burden are overly pessimistic...
  47. pmc Is the major increase in notified campylobacteriosis in New Zealand real?
    M G Baker
    Department of Public Health, Wellington School of Medicine and Health Sciences, Otago University, Wellington, New Zealand
    Epidemiol Infect 135:163-70. 2007
    ..Given the large disease burden, further research and intervention studies should be public health priorities in this country...
  48. pmc Quantifying transmission of Campylobacter spp. among broilers
    T J W M Van Gerwe
    Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL Utrecht, The Netherlands
    Appl Environ Microbiol 71:5765-70. 2005
    ....
  49. pmc Genetic diversity in Campylobacter jejuni is associated with differential colonization of broiler chickens and C57BL/6J IL10-deficient mice
    David L Wilson
    National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 48823, USA
    Microbiology 156:2046-57. 2010
    ..jejuni; the enhancement of genetic diversity at this location may contribute to its importance as a human disease reservoir...
  50. ncbi Genetic diversity among Campylobacter jejuni isolates from pets in Ireland
    E Acke
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Rec 166:102-6. 2010
    ....
  51. pmc Isolation and detection of Campylobacter concisus from saliva of healthy individuals and patients with inflammatory bowel disease
    Li Zhang
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, New South Wales 2052, Australia
    J Clin Microbiol 48:2965-7. 2010
    ..C. concisus was detected in 97% of the healthy individuals and 100% of the patients with IBD tested. The C. concisus culture positivity rate in younger children was significantly lower than that in the other age groups...
  52. ncbi Campylobacter concisus: an emerging pathogen?
    Diane G Newell
    MED VET NET, Veterinary Laboratories Agency, Addlestone, Surrey, UK
    Eur J Gastroenterol Hepatol 17:1013-4. 2005
    ..However, considerable further work is needed with more discriminatory genotyping methods, before accurate assessment of the risk of C. concisus infection to human health can be determined...
  53. ncbi Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium-host interactions
    Boy M Bachtiar
    Biotechnology and Environmental Biology, RMIT University, Melbourne, Australia
    FEMS Immunol Med Microbiol 49:149-54. 2007
    ..jejuni capsular polysaccharides play an important role in adherence to and invasion of human embryonic epithelial cells. However, no significant role of capsular polysaccharides was shown in colonization of the chicken gut...
  54. pmc Standing genetic variation in contingency loci drives the rapid adaptation of Campylobacter jejuni to a novel host
    John P Jerome
    Comparative Enteric Diseases Laboratory, Michigan State University, East Lansing, Michigan, United States of America
    PLoS ONE 6:e16399. 2011
    ..jejuni adaptation and virulence in a novel host...
  55. ncbi Guillain-Barré syndrome after exposure to influenza virus
    Helmar C Lehmann
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, Dusseldorf, Germany
    Lancet Infect Dis 10:643-51. 2010
    ..However, the experiences from the 1976 swine flu vaccination programme emphasise the importance for active and passive surveillance to monitor vaccine safety...
  56. ncbi Association of antimicrobial resistance in Campylobacter isolated from food-producing animals with antimicrobial use on farms
    Tetsuo Asai
    National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Tokyo 185 8511, Japan
    Jpn J Infect Dis 60:290-4. 2007
    ..1% (4/44) and 24.1% (14/58) of the farms where enrofloxacin-resistant C. jejuni and C. coli were isolated, respectively. It is likely that several factors account for the presence of fluoroquinolone-resistant Campylobacter...
  57. doi Colonization strategy of Campylobacter jejuni results in persistent infection of the chicken gut
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Vet Microbiol 130:285-97. 2008
    ..These findings suggest a novel colonization mechanism by escaping rapid mucosal clearance through short-term epithelial invasion and evasion, combined with fast replication in the mucus...
  58. ncbi Campylobacter in poultry: filling an ecological niche
    Margie D Lee
    Department of Population Health, Poultry Diagnostic and Research Center, The University of Georgia, Athens, GA 30602, USA
    Avian Dis 50:1-9. 2006
    ....
  59. pmc Delineation of Campylobacter concisus genomospecies by amplified fragment length polymorphism analysis and correlation of results with clinical data
    Rune Aabenhus
    Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark
    J Clin Microbiol 43:5091-6. 2005
    ..Campylobacter concisus is genetically and taxonomically diverse and contains at least four distinct genomospecies that may exhibit differences in their spectra of virulence potential...
  60. pmc Characterization of the specific interaction between sialoadhesin and sialylated Campylobacter jejuni lipooligosaccharides
    Astrid P Heikema
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands
    Infect Immun 78:3237-46. 2010
    ....
  61. ncbi Quantitative risk assessment of human campylobacteriosis associated with thermophilic Campylobacter species in chickens
    Hanne Rosenquist
    The Danish Veterinary and Food Administration, Institute of Food Safety and Toxicology, Division of Microbiological Safety, 19, Mørkhøj Bygade, 2860 Søborg, Denmark
    Int J Food Microbiol 83:87-103. 2003
    ..Finally, the simulations showed that people in the age of 18-29 years had the highest risk of developing campylobacteriosis...
  62. ncbi Generation of Campylobacter jejuni genetic diversity in vivo
    Paulo de Boer
    Institute for Animal Science and Health, Division of Infectious Diseases and Food Chain Quality, PO Box 65, 8200 AB Lelystad, The Netherlands
    Mol Microbiol 44:351-9. 2002
    ..Together, the data indicate unequivocally that interstrain genetic exchange as well as intragenomic alterations do occur in vivo during C. jejuni infection. These events probably explain the genome plasticity observed for this pathogen...
  63. doi Campylobacter jejuni proteins Cj0952c and Cj0951c affect chemotactic behaviour towards formic acid and are important for invasion of host cells
    A Malik Tareen
    University Medical Center Gottingen, Institute for Medical Microbiology, Kreuzbergring 57, 37075 Gottingen, Germany
    Microbiology 156:3123-35. 2010
    ..jejuni, (iv) alter the chemotactic behaviour of the pathogen towards formic acid, and (v) are not related to the utilization of formic acid by formate dehydrogenase...
  64. ncbi Antecedent infections in Fisher syndrome: a common pathogenesis of molecular mimicry
    M Koga
    Department of Neurology, Dokkyo University School of Medicine, Shimotsuga, Tochigi, Japan
    Neurology 64:1605-11. 2005
    ..To assess the production mechanism of anti-GQ1b autoantibody in Fisher syndrome (FS)...
  65. ncbi The paternal effect of Campylobacter jejuni colonization in ceca in broilers
    X Li
    Department of Poultry Science, Texas A and M University, College Station 77843, USA
    Poult Sci 87:1742-7. 2008
    ..jejuni counts in cloacal swabs and those in cecal contents. The results indicated that a paternal effect might be one of the important genetic factors influencing resistance to C. jejuni colonization in broilers...
  66. doi Incidence and ecology of Campylobacter jejuni and coli in animals
    S M Horrocks
    United States Department of Agriculture, Southern Plains Agricultural Research Center, College Station, TX 77845, USA
    Anaerobe 15:18-25. 2009
    ..Such multiple hurdle approaches that simultaneously utilize pre- and post-harvest control techniques are expected to be the most effective approach for decreasing human illness associated with foodborne pathogens...
  67. pmc Attribution of Campylobacter infections in northeast Scotland to specific sources by use of multilocus sequence typing
    Norval J C Strachan
    School of Biological Sciences, University of Aberdeen, Aberdeen, United Kingdom
    J Infect Dis 199:1205-8. 2009
    ..The results indicate that chicken is a major source of infection in young urban children, although not in their rural counterparts, for which ruminant and other avian sources are more important...
  68. pmc Gamma-glutamyl transpeptidase has a role in the persistent colonization of the avian gut by Campylobacter jejuni
    If H A Barnes
    Veterinary Laboratories Agency Weybridge, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, UK
    Microb Pathog 43:198-207. 2007
    ..In vivo studies showed that, although GGT activity was not required for initial colonization of 1-day-old chicks, the enzyme was required for persistent colonization of the avian gut...
  69. pmc Estimating community incidence of Salmonella, Campylobacter, and Shiga toxin-producing Escherichia coli infections, Australia
    Gillian Hall
    Australian National University, Acton, Australian Capital Territory, Australia
    Emerg Infect Dis 14:1601-9. 2008
    ..Estimation of multipliers allows assessment of the true effects of these diseases and better understanding of public health surveillance...
  70. pmc Use of genome-wide expression profiling and mutagenesis to study the intestinal lifestyle of Campylobacter jejuni
    Alain Stintzi
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Infect Immun 73:1797-810. 2005
    ..Overall, this study provides new insights on the mechanisms of gut colonization, as well as possible strategies employed by Campylobacter to resist or evade the host immune responses...
  71. pmc Quinolone-resistant Campylobacter infections: risk factors and clinical consequences
    Jørgen Engberg
    Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark
    Emerg Infect Dis 10:1056-63. 2004
    ..jejuni infections. An association between treatment with a fluoroquinolone before stool-specimen collection and having a quinolone-resistant C. jejuni infection was not observed...
  72. pmc Rapid pulsed-field gel electrophoresis protocol for subtyping of Campylobacter jejuni
    E M Ribot
    Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    J Clin Microbiol 39:1889-94. 2001
    ..Comparison of PFGE patterns obtained in six laboratories showed that subtyping results obtained using this protocol are highly reproducible...
  73. ncbi Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni
    David J McNally
    Institute for Biological Sciences, National Research Council of Canada, 100 Sussex Drive, Ottawa, Ontario K1A 0R6, Canada
    J Biol Chem 282:28566-76. 2007
    ..These findings establish the importance of the MeOPN as a diagnostic marker and therapeutic target for C. jejuni and set the groundwork for future studies aimed at the detailed elucidation of the MeOPN biosynthetic pathway...
  74. pmc Genome dynamics of Campylobacter jejuni in response to bacteriophage predation
    Andrew E Scott
    Division of Food Sciences, University of Nottingham, Loughborough, United Kingdom
    PLoS Pathog 3:e119. 2007
    ..jejuni exists in vivo as families of related meta-genomes generated to survive local environmental pressures...
  75. ncbi The physiology of Campylobacter species and its relevance to their role as foodborne pathogens
    Simon F Park
    School of Biomedical and Life Sciences, University of Surrey, Guildford, UK
    Int J Food Microbiol 74:177-88. 2002
    ..The aim of this review is to outline the unusual physiology of campylobacters (C. jejuni and C. coli) and to describe how this influences their role as foodborne pathogens...
  76. ncbi Macrolide resistance in Campylobacter jejuni and Campylobacter coli
    Amera Gibreel
    Department of Medical Microbiology and Immunology, University of Alberta Edmonton, Alberta, Canada
    J Antimicrob Chemother 58:243-55. 2006
    ..Mechanisms implicated in macrolide resistance in C. jejuni and also techniques that have been developed for the efficient detection of macrolide-associated mutation(s) will be discussed in detail...
  77. pmc Effect of Campylobacter-specific maternal antibodies on Campylobacter jejuni colonization in young chickens
    Orhan Sahin
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio 44691, USA
    Appl Environ Microbiol 69:5372-9. 2003
    ....
  78. pmc Fly transmission of Campylobacter
    Gordon L Nichols
    Environmental and Enteric Diseases Department, Communicable Disease Surveillance Centre, Health Protection Agency Centre for Infections, 61 Colindale Ave, London NW9 5EQ, UK
    Emerg Infect Dis 11:361-4. 2005
    ..The hypothesis provides an explanation for the seasonal distribution of Campylobacter infections seen around the world.
  79. pmc Transmission of Campylobacter hyointestinalis from a pig to a human
    Gregor Gorkiewicz
    Institute of Molecular Biology, Biochemistry and Microbiology, Karl Franzens University, Graz, Austria
    J Clin Microbiol 40:2601-5. 2002
    ..hyointestinalis strain originating from porcine feces. Subsequent typing of the human and the porcine isolates by pulsed-field gel electrophoresis revealed similar macrorestriction profiles, indicating transmission of this pathogen...
  80. pmc Molecular epidemiology of Campylobacter jejuni in a geographically isolated country with a uniquely structured poultry industry
    Petra Mullner
    Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Private Bag 11 222, Palmerston North, New Zealand
    Appl Environ Microbiol 76:2145-54. 2010
    ..jejuni has a distinctive molecular epidemiology in this country. These results may be due in part to New Zealand's geographical isolation and its uniquely structured poultry industry...
  81. ncbi Summary of the Swedish Campylobacter program in broilers, 2001 through 2005
    I Hansson
    Department of Bacteriology, National Veterinary Institute, SE 751 89 Uppsala, Sweden
    J Food Prot 70:2008-14. 2007
    ..During the study period, about one-third of producers seldom delivered Campylobacter-positive batches (< 10% positive batches per year). Thus, it is possible to produce Campylobacter-free broilers in Sweden...
  82. pmc Marked campylobacteriosis decline after interventions aimed at poultry, New Zealand
    Ann Sears
    University of Otago, Wellington, New Zealand
    Emerg Infect Dis 17:1007-15. 2011
    ..contamination of poultry. The apparent success of these interventions may inform approaches other countries could consider to help control foodborne campylobacteriosis...
  83. ncbi Weather and notified Campylobacter infections in temperate and sub-tropical regions of Australia: an ecological study
    Peng Bi
    Discipline of Public Health, University of Adelaide, North Terrace, Adelaide, SA 5005, Australia
    J Infect 57:317-23. 2008
    ..This study was designed to quantify the relationship between weather variables and Campylobacter infections in two Australian cities with different local climatic conditions.
  84. ncbi Campylobacter jejuni--microtubule-dependent invasion
    D J Kopecko
    Laboratory of Enteric and Sexually Transmitted Diseases, FDA Center for Biologics Evaluation and Research, Bldg 29 420, NIH Campus, Bethesda, MD 20892, USA
    Trends Microbiol 9:389-96. 2001
    ..current evidence suggests that C. jejuni use some markedly different molecular mechanisms of pathogenesis compared with shigellae...
  85. doi Campylobacter ureolyticus: an emerging gastrointestinal pathogen?
    Susan Bullman
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    FEMS Immunol Med Microbiol 61:228-30. 2011
    ..This is, to the best of our knowledge, the first report of C. ureolyticus in the faeces of patients presenting with gastroenteritis and may suggest a role for this organism as an emerging enteric pathogen...
  86. ncbi Outbreaks of campylobacteriosis in Australia, 2001 to 2006
    Leanne E Unicomb
    National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australian Capital Territory, Australia
    Foodborne Pathog Dis 6:1241-50. 2009
    ..In addition to detection of chicken as a common source of outbreaks, these data highlight the importance of directing policy at commercial premises, aged care facilities, and school camps to reduce Campylobacter disease burden...
  87. pmc Sequencing and validation of the genome of a Campylobacter concisus reveals intra-species diversity
    Nandan P Deshpande
    Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, New South Wales, Australia
    PLoS ONE 6:e22170. 2011
    ..Many of the observed differences are consistent with UNSWCD having adapted to greater surface interaction with host cells, as opposed to BAA-1457 which may prefer a free-living environment...
  88. pmc Quantifying transmission of Campylobacter jejuni in commercial broiler flocks
    Twan van Gerwe
    Department of Farm Animal Health, Utrecht University, The Netherlands
    Appl Environ Microbiol 75:625-8. 2009
    ..This study provides an important quantitative estimate of the rate of transmission of Campylobacter in broiler flocks, which could be helpful in future studies on the epidemiology of Campylobacter in the field...
  89. pmc Identification of Campylobacter jejuni genes involved in its interaction with epithelial cells
    Veronica Novik
    Section of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Ave, New Haven, CT 06536, USA
    Infect Immun 78:3540-53. 2010
    ..jejuni entry and/or survival within host cells and a severe defect in colonization in an animal model. The implications of these findings for the understanding of C. jejuni-host cell interactions are discussed...
  90. ncbi Characterization and subgrouping of Campylobacter concisus strains using protein profiles, conventional biochemical testing and antibiotic susceptibility
    Rune Aabenhus
    Department of Clinical Microbiology, National University Hospital Rigshospitalet, Denmark
    Eur J Gastroenterol Hepatol 17:1019-24. 2005
    ..To characterize and subgroup clinical strains of Campylobacter concisus isolated from patients with gastrointestinal disease...
  91. pmc Multiple factors interact to produce responses resembling spectrum of human disease in Campylobacter jejuni infected C57BL/6 IL-10-/- mice
    Julia A Bell
    Comparative Enteric Diseases Laboratory, National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA
    BMC Microbiol 9:57. 2009
    ..We took a comparative experimental approach to explore differences among different C. jejuni strains and studied the effect of diet on disease manifestation in an interleukin-10 deficient mouse model...
  92. pmc First attempt to produce experimental Campylobacter concisus infection in mice
    Rune Aabenhus
    Department of Clinical Microbiology, National University Hospital Rigshospitalet, Copenhagen, Denmark
    World J Gastroenterol 14:6954-9. 2008
    ..To infect mice with atypical Campylobacter concisus (C. concisus) for the first time...
  93. ncbi Distribution of serotypes of Campylobacter jejuni and C. coli from Danish patients, poultry, cattle and swine
    E M Nielsen
    Department of Microbiology, Danish Veterinary Laboratory, Copenhagen, Denmark
    FEMS Immunol Med Microbiol 19:47-56. 1997
    ..The serotype distribution of human clinical isolates showed large overlap with the serotype distribution of campylobacters in cattle and chickens, and on this basis both could be major sources of human campylobacteriosis...
  94. pmc Multilocus sequence typing of Campylobacter jejuni isolates from humans, chickens, raw milk, and environmental water in Quebec, Canada
    Simon Levesque
    Department of Microbiology and Infectious Diseases, Faculté de Médecine de l Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, Quebec J1H 5N4, Canada
    J Clin Microbiol 46:3404-11. 2008
    ..Although MLST is labor-intensive and expensive, it remains the single best method for the genotyping of C. jejuni isolates and deciphering the epidemiologic relationships among isolates...
  95. ncbi A large multi-pathogen waterborne community outbreak linked to faecal contamination of a groundwater system, France, 2000
    A Gallay
    Institut de Veille Sanitaire, Saint Maurice, France
    Clin Microbiol Infect 12:561-70. 2006
    ..This is the first documented waterborne outbreak of infection involving human C. coli infections. A better understanding of the factors influencing campylobacter transmission between hosts is required...
  96. ncbi Campylobacters as zoonotic pathogens: a food production perspective
    Tom Humphrey
    University of Bristol, Division of Veterinary Pathology, Infection and Immunity, School of Clinical Veterinary Sciences, The Churchill Building, Langford, Bristol BS40 5DU, United Kingdom
    Int J Food Microbiol 117:237-57. 2007
    ..There is also a need to better understand the reasons why campylobacters are capable of frequent change, particularly in the expression of surface antigens...
  97. ncbi Regulation of chicken contamination is urgently needed to control New Zealand's serious campylobacteriosis epidemic
    Michael Baker
    Wellington School of Medicine and Health Sciences, University of Otago
    N Z Med J 119:U2264. 2006
    ....
  98. pmc Tracing the source of campylobacteriosis
    Daniel J Wilson
    Department of Maths and Statistics, Lancaster University, Lancaster, United Kingdom
    PLoS Genet 4:e1000203. 2008
    ..Our results imply that the primary transmission route is through the food chain, and suggest that incidence could be dramatically reduced by enhanced on-farm biosecurity or preventing food-borne transmission...
  99. ncbi Influence of Campylobacter jejuni fliA, rpoN and flgK genes on colonization of the chicken gut
    Ursla Fernando
    Vaccine and Infectious Disease Organization, 120 Veterinary Road, Saskatoon, Saskatchewan, Canada S7N 5E3
    Int J Food Microbiol 118:194-200. 2007
    ..jejuni, is required for assembly of the flagellar secretory apparatus and an flgK mutant of C. jejuni expressing only the hook showed diminished motility and was completely attenuated for cecal colonization in chickens...
  100. pmc Guillain-Barré syndrome and preceding infection with campylobacter, influenza and Epstein-Barr virus in the general practice research database
    Clarence C Tam
    Infectious Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 2:e344. 2007
    ..A number of infectious agents have previously been suggested as risk factors for the development of Guillain-Barré syndrome (GBS), but robust epidemiologic evidence for these associations is lacking...
  101. pmc Population-attributable risk estimates for risk factors associated with Campylobacter infection, australia
    Russell J Stafford
    Queensland Health, Brisbane, Queensland, Australia
    Emerg Infect Dis 14:895-901. 2008
    ..Our statistical technique could be applied more widely to other communicable diseases that are subject to routine surveillance...

Research Grants76

  1. Oligosaccharides to Prevent Infectious Diarrhea
    JOHN MICHAEL MCCOY; Fiscal Year: 2010
    ..By far the highest incidence of Campylobacter infections is in children <5 yrs of age[13][14][15]...
  2. CELL-SURFACE PROTEINS IN CAMPYLOBACTER FETUS VIRULENCE
    Geraldine Miller; Fiscal Year: 1990
    Human campylobacter infections have been increasingly recognized ass major causes of human illness. Campylobacter jejuni is now recognized as the most common bacterial cause of invasive diarrhea in the United States...
  3. Antimicrobial peptide resistance in Campylobacter jejuni
    Jun Lin; Fiscal Year: 2010
    ..Contaminated poultry meats are considered a significant source for human Campylobacter infections. Increasing resistance of C...
  4. Antimicrobial peptide resistance in Campylobacter jejuni
    Jun Lin; Fiscal Year: 2009
    ..Contaminated poultry meats are considered a significant source for human Campylobacter infections. Increasing resistance of C...
  5. Environmental Health Specialist Network
    RICHARD NORMAN DANILA; Fiscal Year: 2010
    ..Special studies to identify the burden of Cryptosporidium, Shiga toxin-producing E. coli, and Campylobacter infections due to drinking water, along with practices, behaviors, or other risk factors that lead to sporadic ..
  6. Campylobacter colonization and virulence determinants
    Alain Stintzi; Fiscal Year: 2007
    ..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
  7. Campylobacter colonization and virulence determinants
    Alain Stintzi; Fiscal Year: 2006
    ..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
  8. Campylobacter colonization and virulence determinants
    Alain Stintzi; Fiscal Year: 2005
    ..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
  9. Campylobacter colonization and virulence determinants
    Alain Stintzi; Fiscal Year: 2004
    ..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
  10. Campylobacter colonization and virulence determinants
    Alain Stintzi; Fiscal Year: 2005
    ..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
  11. Campylobacter colonization and virulence determinants
    Alain Stintzi; Fiscal Year: 2003
    ..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
  12. CELL-SURFACE PROTEINS IN CAMPYLOBACTER FETUS VIRULENCE
    Geraldine Miller; Fiscal Year: 1992
    b>Campylobacter infections have been increasingly recognized as major causes of human illness...
  13. Analysis of Campylobacter coli Lipooligosaccharide Core Diversity
    MARGARET KANIPES; Fiscal Year: 2006
    ..A small but significant number of Campylobacter infections have also been linked to the development of Guillain Barre Syndrome (GBS)...
  14. 14th International CHRO Workshop
    Irving Nachamkin; Fiscal Year: 2007
    ..abstract_text> ..
  15. 13th International Campylobacter/Helicobacter workshop
    Irving Nachamkin; Fiscal Year: 2005
    ..abstract_text> ..
  16. HOST FACTORS MEDIATE INVASION BY CAMPYLOBACTER JEJUNI
    LINDA MANSFIELD; Fiscal Year: 2002
    ..jejuni invasion is facilitated due to a direct effect of some secreted/excreted product of the worms, and 4) Determine what host cell genes are differentially expressed during C. jejuni invasion. ..
  17. Murine models to test parasite products as cures for Inflammatory Bowel Disease
    LINDA MANSFIELD; Fiscal Year: 2008
    ..Dr. Mansfield has documented success mentoring graduate students and seeks to expand her mentoring of D.V.M.s in mouse pathobiology. ..
  18. Murine models to test parasite products as cures for Inflammatory Bowel Disease
    LINDA MANSFIELD; Fiscal Year: 2007
    ..Dr. Mansfield has documented success mentoring graduate students and seeks to expand her mentoring of D.V.M.s in mouse pathobiology. ..
  19. Pathogenesis of Campylobacter enteritis:
    MICHAEL KONKEL; Fiscal Year: 2005
    ..jejuni, and will be useful in the development of intervention and control methods to reduce the number of cases of human campylobacteriosis. ..
  20. Pathogenesis of Campylobacter enteritis:
    MICHAEL KONKEL; Fiscal Year: 2001
    ..jejuni, and will be useful in the development of intervention and control methods to reduce the number of cases of human campylobacteriosis. ..
  21. Pathogenesis of Campylobacter enteritis:
    MICHAEL KONKEL; Fiscal Year: 2004
    ..jejuni, and will be useful in the development of intervention and control methods to reduce the number of cases of human campylobacteriosis. ..
  22. Pathogenesis of Campylobacter enteritis:
    MICHAEL KONKEL; Fiscal Year: 2002
    ..jejuni, and will be useful in the development of intervention and control methods to reduce the number of cases of human campylobacteriosis. ..
  23. Development and evaluation of subunit vaccine CmeC against Campylobacter jejuni
    Jun Lin; Fiscal Year: 2008
    ..for the development of alternative intervention strategies, such as vaccination, to prevent and control Campylobacter infections. Despite recent progress on the elucidation of immunogenic and protective antigens in C...
  24. Development and evaluation of subunit vaccine CmeC against Campylobacter jejuni
    Jun Lin; Fiscal Year: 2007
    ..for the development of alternative intervention strategies, such as vaccination, to prevent and control Campylobacter infections. Despite recent progress on the elucidation of immunogenic and protective antigens in C...
  25. Pathogenesis of Campylobacter enteritis:
    MICHAEL KONKEL; Fiscal Year: 2003
    ..jejuni, and will be useful in the development of intervention and control methods to reduce the number of cases of human campylobacteriosis. ..
  26. Glycosylation of Campylobacter flagella
    Patricia Guerry; Fiscal Year: 2007
    ..The biological role of flagella glycosylation will be studied by examining a series of mutants in in vitro and in vivo assays of virulence. ..
  27. Glycosylation of Campylobacter flagella
    Patricia Guerry; Fiscal Year: 2006
    ..The biological role of flagella glycosylation will be studied by examining a series of mutants in in vitro and in vivo assays of virulence. ..
  28. SIALYLATED SURFACE ANTIGENS OF CAMPYLOBACTER SPP
    Patricia Guerry; Fiscal Year: 2000
    ..jejuni, MSC57360 and 81-176; and 3. Measure the virulence and immunogenicity of mutants of VC167, MSC, and 81-176 which are defective in post-translational modification genes and/or have non-sialylated LPS. ..
  29. Glycosylation of Campylobacter flagella
    Patricia Guerry; Fiscal Year: 2005
    ..The biological role of flagella glycosylation will be studied by examining a series of mutants in in vitro and in vivo assays of virulence. ..
  30. SIALYLATED SURFACE ANTIGENS OF CAMPYLOBACTER SPP
    Patricia Guerry; Fiscal Year: 1999
    ..jejuni, MSC57360 and 81-176; and 3. Measure the virulence and immunogenicity of mutants of VC167, MSC, and 81-176 which are defective in post-translational modification genes and/or have non-sialylated LPS. ..
  31. Glycosylation of Campylobacter flagella
    Patricia Guerry; Fiscal Year: 2004
    ..The biological role of flagella glycosylation will be studied by examining a series of mutants in in vitro and in vivo assays of virulence. ..
  32. Glycosylation of Campylobacter flagella
    Patricia Guerry; Fiscal Year: 2003
    ..The biological role of flagella glycosylation will be studied by examining a series of mutants in in vitro and in vivo assays of virulence. ..
  33. Capsule conjugate vaccines against ETEC and Campylobacter
    Patricia Guerry; Fiscal Year: 2010
    ..Multiple conjugates could be combined into a multi-valent vaccine that would afford protection against the major antigenic variants of both pathogens. ..
  34. SIALYLATED SURFACE ANTIGENS OF CAMPYLOBACTER SPP
    Patricia Guerry; Fiscal Year: 2001
    ..jejuni, MSC57360 and 81-176; and 3. Measure the virulence and immunogenicity of mutants of VC167, MSC, and 81-176 which are defective in post-translational modification genes and/or have non-sialylated LPS. ..
  35. Pandemic influenza control at the borders of island countries and in household
    Michael Baker; Fiscal Year: 2008
    ..Findings from the housing cohort would be used to guide advice about reducing influenza transmission in households, particularly in terms of crowding levels and exposure to active and passive smoking. ..
  36. Pandemic influenza control at the borders of island countries and in household
    Michael Baker; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  37. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2010
    ..The findings will also help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
  38. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2007
    ..The findings will also help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
  39. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2009
    ..The findings will also help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
  40. Immunoglobulin Allotypes in Hepatitis C Virus Infection
    JANARDAN PANDEY; Fiscal Year: 2008
    ..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. ..
  41. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2008
    ..The findings will also help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
  42. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2007
    ..The findings will help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
  43. Immunoglobulin Allotypes in Hepatitis C Virus Infection
    JANARDAN PANDEY; Fiscal Year: 2007
    ..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. [unreadable] [unreadable]..
  44. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2004
    ..jejuni and may open new avenues for the design of effective means to prevent and treat antibiotics-resistant Campylobacter. ..
  45. Gamma-Delta T cells and Cryptosporidiosis
    Beth Kirkpatrick; Fiscal Year: 2008
    ..These data will advance our understanding of the mucosal immune response to cryptosporidiosis, which will lead to further advances in prevention and therapy. ..
  46. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2003
    ..jejuni and may open new avenues for the design of effective means to prevent and treat antibiotics-resistant Campylobacter. ..
  47. Mechanisms of antibiotic efflux in Campylobacter
    Qijing Zhang; Fiscal Year: 2005
    ..jejuni and may open new avenues for the design of effective means to prevent and treat antibiotics-resistant Campylobacter. ..
  48. Immunoglobulin Allotypes in Hepatitis C Virus Infection
    JANARDAN PANDEY; Fiscal Year: 2006
    ..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. [unreadable] [unreadable]..
  49. Gamma-Delta T cells and Cryptosporidiosis
    Beth Kirkpatrick; Fiscal Year: 2007
    ..These data will advance our understanding of the mucosal immune response to cryptosporidiosis, which will lead to further advances in prevention and therapy. ..
  50. IN VIVO PATHOGENESIS OF HELICOBACTER PYLORI
    James Fox; Fiscal Year: 2006
    ..pylori pathogenesis and specifically evaluate the role of regulatory T cells in limiting H. pylori-induced gastric pathology. ..
  51. Mechanisms of Interleukin-17 Inflammation Induced by Bacteroides fragilis
    CYNTHIA SEARS; Fiscal Year: 2009
    ....
  52. IN VIVO PATHOGENESIS OF HELICOBACTER PYLORI
    James Fox; Fiscal Year: 2003
    ....
  53. PHYSIOLOGY AND CLONING OF B FRAGILIS ENTEROTOXIN
    CYNTHIA SEARS; Fiscal Year: 2009
    ..Our studies may indicate that a common stool bacterium is oncogenic and contributes to colon cancer risk. If so, these data will lead to new public health approaches to the prevention of colon cancer. ..
  54. Breast milk: Physiology, Biochemistry and Outcomes
    Ardythe Morrow; Fiscal Year: 2006
    ..A list of these publications is found on our society's website (www.isrhml.org.umu.se). [unreadable] [unreadable] [unreadable]..
  55. Pathogenicity of Enterotoxigenic Bacteriodes Fragilis
    CYNTHIA SEARS; Fiscal Year: 2001
    ..We hypothesize that ETBF is an under-recognized intestinal pathogen accounting for a portion of previously undiagnosed inflammatory intestinal infections in both children and adults. ..
  56. Campylobacter jejuni flagellar regulation and synthesis
    David R Hendrixson; Fiscal Year: 2010
    ..The proposed research activities will determine how certain proteins of C.jejunifunction together to control production of flagellar proteins that make up the flagellar structure. ..
  57. Helicobacter induced hepatitis and tumorigenesis
    James Fox; Fiscal Year: 2009
    ..A more complete understanding of the etiopathogenesis of hepatobiliary disease and hepatocellular carcinoma is likely to result in new strategies for treatment and prevention of these important human diseases. ..
  58. PHYSIOLOGY AND CLONING OF B FRAGILIS ENTEROTOXIN
    CYNTHIA SEARS; Fiscal Year: 1999
    ..This three-pronged approach will advance our understanding of the molecular pathogenesis of ETBF infections and will serve to delineate in much greater detail the cellular mechanism of action of BFT. ..
  59. Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants.
    Ardythe Morrow; Fiscal Year: 2009
    ....
  60. Physiology and Cloning of B. Fragilis Enterotoxin
    CYNTHIA SEARS; Fiscal Year: 2004
    ..abstract_text> ..
  61. Mechanisms of Interleukin-17 Inflammation Induced by Bacteroides fragilis
    CYNTHIA SEARS; Fiscal Year: 2008
    ....
  62. Practical Diagnostics for AIDS-Related Pediatric TB,Peru
    Richard Oberhelman; Fiscal Year: 2004
    ..These new diagnostic methods have tremendous potential to improve and simplify the diagnosis of pediatric tuberculosis in low-income countries with limited laboratory resources. ..
  63. Neurocircuitry of Illness Induced Behavioral Depression
    LISA GOEHLER; Fiscal Year: 2006
    ....
  64. Neurocircuitry of Illness Induced Behavioral Depression
    LISA GOEHLER; Fiscal Year: 2008
    ....
  65. Helicobacter induced hepatitis and tumorigenesis
    James Fox; Fiscal Year: 2004
    ..A more complete understanding of the etiopathogenesis of hepatobiliary disease and hepatocellular carcinoma is likely to result in new strategies for treatment and prevention of these important human diseases. ..
  66. Genetic Analysis of Campylobacter jejuni Colonization
    DAVID HENDRIXSON; Fiscal Year: 2003
    ..jejuni to identify genes required for chicken colonization. This last aim will allow us to begin to understand requirements of C. jejuni for colonization of a natural host. ..
  67. Campylobacter jejuni flagellar regulation and synthesis
    DAVID HENDRIXSON; Fiscal Year: 2009
    ..The proposed research activities will determine how certain proteins of C.jejunifunction together to control production of flagellar proteins that make up the flagellar structure. ..
  68. Campylobacter jejuni flagellar regulation and synthesis
    DAVID HENDRIXSON; Fiscal Year: 2007
    ..The proposed research activities will determine how certain proteins of C. jejuni function together to control production of flagellar proteins that make up the flagellar structure. [unreadable] [unreadable] [unreadable]..
  69. Campylobacter jejuni flagellar regulation and synthesis
    DAVID HENDRIXSON; Fiscal Year: 2008
    ..The proposed research activities will determine how certain proteins of C.jejunifunction together to control production of flagellar proteins that make up the flagellar structure. ..
  70. Campylobacter jejuni flagellar regulation and synthesis
    DAVID HENDRIXSON; Fiscal Year: 2006
    ..The proposed research activities will determine how certain proteins of C. jejuni function together to control production of flagellar proteins that make up the flagellar structure. [unreadable] [unreadable] [unreadable]..
  71. Campylobacter jejuni flagellar regulation and synthesis
    David R Hendrixson; Fiscal Year: 2010
    ..The proposed research activities will determine how certain proteins of C.jejunifunction together to control production of flagellar proteins that make up the flagellar structure. ..