Genomes and Genes
Summary: Infections with bacteria of the genus CAMPYLOBACTER.
Publications262 found, 100 shown here
- Prevalence of Campylobacter, Arcobacter, Helicobacter, and Sutterella spp. in human fecal samples as estimated by a reevaluation of isolation methods for CampylobactersJ Engberg
Department of Gastrointestinal Infections, Division of Diagnostics, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
J Clin Microbiol 38:286-91. 2000..Further investigations to establish the role of C. concisus and S. wadsworthensis in enteric disease is needed. We conclude that a range of campylobacteria may cause infections in Denmark...
- Campylobacter concisus: an evaluation of certain phenotypic and genotypic characteristicsJ Engberg
Unit of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, Denmark
Clin Microbiol Infect 11:288-95. 2005..Further evidence is needed to support the possible role of C. concisus as a human enteric pathogen...
- Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control studyY Doorduyn
Epidemiology and Surveillance Unit, Netherlands Centre for Infectious Disease Control, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Epidemiol Infect 138:1391-404. 2010..jejuni infections. This study illustrates that important differences in risk factors exist for different Campylobacter spp. and these may differ dependent on age, season or degree of urbanization...
- L-fucose utilization provides Campylobacter jejuni with a competitive advantageMartin Stahl
Department of Biochemistry, Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada
Proc Natl Acad Sci U S A 108:7194-9. 2011..This identifies a previously unrecorded metabolic pathway in select strains of C. jejuni associated with a virulent lifestyle...
- Characterization of a haemolytic phospholipase A(2) activity in clinical isolates of Campylobacter concisusTaghrid S Istivan
Department of Biotechnology and Environmental Biology, RMIT University, PO Box 71, Bundoora, Victoria 3083, Australia
J Med Microbiol 53:483-93. 2004..concisus. The detection of haemolytic PLA(2) activity in C. concisus indicates the presence of a potential virulence factor in this species and supports the hypothesis that C. concisus is a possible opportunistic pathogen...
- Prevalence of Campylobacter concisus in diarrhoea of immunocompromised patientsRune Aabenhus
Department of Infectious Diseases, National University Hospital, Copenhagen, Denmark
Scand J Infect Dis 34:248-52. 2002..C. concisus may be a frequent cause of diarrhoea in immunocompromised patients. Two groups of C. concisus were found and these groups possibly vary in their pathogenic potential...
- MUC1 cell surface mucin is a critical element of the mucosal barrier to infectionJulie L McAuley
Mucosal Diseases Program, Mater Medical Research Institute and The University of Queensland, South Brisbane, Queensland, Australia
J Clin Invest 117:2313-24. 2007....
- Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunityStefan Bereswill
Department of Microbiology and Hygiene, Charite University Medicine Berlin, Berlin, Germany
PLoS ONE 6:e20953. 2011..Detailed investigation of C. jejuni-mediated intestinal immunopathology is hampered by the lack of appropriate vertebrate models. In particular, mice display colonization resistance against this pathogen...
- Enteric Salmonella or Campylobacter infections and the risk of inflammatory bowel diseaseTine Jess
Department of Epidemiology Research, Statens Serum Institut, Copenhagen S, Denmark
Gut 60:318-24. 2011....
- Detection and isolation of Campylobacter species other than C. jejuni from children with Crohn's diseaseLi Zhang
School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia
J Clin Microbiol 47:453-5. 2009..concisus and higher levels of antibodies to C. concisus were detected in children with Crohn's disease (CD) than in controls. Campylobacter species other than C. jejuni were isolated from intestinal biopsy specimens of children with CD...
- Campylobacter genotyping to determine the source of human infectionSamuel K Sheppard
Department of Zoology, University of Oxford, Oxford, United Kingdom
Clin Infect Dis 48:1072-8. 2009....
- Host association of Campylobacter genotypes transcends geographic variationSamuel K Sheppard
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
Appl Environ Microbiol 76:5269-77. 2010..These findings are consistent with local and international transmission of host-associated lineages among food animal species and provide a foundation for further improvements in genetic attribution...
- Metabolic diversity in Campylobacter jejuni enhances specific tissue colonizationDirk Hofreuter
Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA
Cell Host Microbe 4:425-33. 2008..In addition, these studies revealed remarkably specific nutritional requirements for a pathogen to effectively colonize different tissues...
- Epidermal growth factor inhibits Campylobacter jejuni-induced claudin-4 disruption, loss of epithelial barrier function, and Escherichia coli translocationJennifer M Lamb-Rosteski
Department of Biological Sciences, Inflammation Research Network, University of Calgary, 2500 University Dr N W, Calgary, Alberta T2N 1N4, Canada
Infect Immun 76:3390-8. 2008..These findings highlight EGF's ability to alter colonization of C. jejuni in the intestinal tract and to protect against pathogen-induced barrier defects...
- Detection of Campylobacter concisus and other Campylobacter species in colonic biopsies from adults with ulcerative colitisIndrani Mukhopadhya
Gastrointestinal Research Group, Division of Applied Medicine, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom
PLoS ONE 6:e21490. 2011..This study investigated the prevalence of Campylobacter species in colonic biopsy samples from adults with UC and healthy controls...
- The clinical importance of emerging Campylobacter speciesSi Ming Man
Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK
Nat Rev Gastroenterol Hepatol 8:669-85. 2011..This Review presents the latest information on the role and clinical importance of emerging Campylobacter spp. in gastrointestinal health and disease...
- Comparison of molecular typing methods useful for detecting clusters of Campylobacter jejuni and C. coli isolates through routine surveillanceClifford G Clark
National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
J Clin Microbiol 50:798-809. 2012..Similarly, comparing several different typing methods reveals a great deal about differences in how the methods group individuals within the population...
- Campylobacter concisus and other Campylobacter species in children with newly diagnosed Crohn's diseaseSi Ming Man
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia
Inflamm Bowel Dis 16:1008-16. 2010..To further investigate this issue we determined the prevalence of these organisms in pediatric patients newly diagnosed with CD...
- Correlation between invasion of Caco-2 eukaryotic cells and colonization ability in the chick gut in Campylobacter jejuniI Hanel
Federal Research Centre for Virus Diseases of Animals, Institute of Molecular Pathogenesis, Jena, Naumburger Str 96a, 07743 Jena, Germany
Vet Microbiol 101:75-82. 2004..The characterization of the flagellin gene of the used C. jejuni strains resulted in eight flaA types. There was no association between flaA type and invasion or colonization ability in the chick gut...
- The health burden of Campylobacter infection and the impact of antimicrobial resistance: playing chickenGuillermo M Ruiz-Palacios
Clin Infect Dis 44:701-3. 2007
- Molecular and spatial epidemiology of human campylobacteriosis: source association and genotype-related risk factorsP Mullner
Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand
Epidemiol Infect 138:1372-83. 2010..In particular young children in rural areas had a higher risk of infection with ruminant strains than their urban counterparts. These findings provide important information for the implementation of pathway-specific control strategies...
- Antibiotic resistance in Campylobacter: emergence, transmission and persistenceTaradon Luangtongkum
Department of Veterinary Microbiology and Preventive Medicine, 1116 Veterinary Medicine Complex, Iowa State University, Ames, IA 500111, USA
Future Microbiol 4:189-200. 2009..A future perspective on antibiotic resistance and potential approaches for the control of antibiotic-resistant Campylobacter, will also be discussed...
- Campylobacter sugars sticking outPatricia Guerry
Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
Trends Microbiol 16:428-35. 2008..The exciting surge in recent research activities will be summarized in this review...
- Campylobacter jejuni: molecular biology and pathogenesisKathryn T Young
Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, USA
Nat Rev Microbiol 5:665-79. 2007..Comparing the different host responses to C. jejuni colonization should increase our understanding of this organism...
- Climate variability and campylobacter infection: an international studyR Sari Kovats
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Int J Biometeorol 49:207-14. 2005..The main driver of seasonality of campylobacter remains elusive and underscores the need to identify the major serotypes and routes of transmission for this disease...
- Assigning the source of human campylobacteriosis in New Zealand: a comparative genetic and epidemiological approachPetra Mullner
Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand
Infect Genet Evol 9:1311-9. 2009..The comparative-modeling and molecular sentinel surveillance approach proposed in this study provides new opportunities for the management of zoonotic diseases...
- Campylobacter jejuni: a brief overview on pathogenicity-associated factors and disease-mediating mechanismsJavid I Dasti
Institute of Medical Microbiology, University Medical Centre Göttingen, Kreuzbergring 57, D 37075 Gottingen, Germany
Int J Med Microbiol 300:205-11. 2010..Indeed, several lines of evidence suggest exploitation of different adaptation strategies by this pathogen depending on its requirement, whether to establish itself in the natural avian reservoir or during the course of human infection...
- The epidemiology of antibiotic resistance in CampylobacterJohn E Moore
Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
Microbes Infect 8:1955-66. 2006....
- Activation of human and chicken toll-like receptors by Campylobacter sppMarcel R de Zoete
Department of Infectious Diseases and Immunology, Utrecht University, P O Box 80 165, 3508 TD Utrecht, The Netherlands
Infect Immun 78:1229-38. 2010..The results suggest that differences in bacterial cell wall integrity and in TLR responses to Campylobacter LOS and/or DNA may contribute to the distinct clinical manifestation between the species...
- Wide geographical distribution of internationally rare Campylobacter clones within New ZealandS M McTavish
ESR Ltd, Kenepuru Science Centre, Porirua, New Zealand
Epidemiol Infect 136:1244-52. 2008....
- Host-pathogen interactions in Campylobacter infections: the host perspectiveRiny Janssen
Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Clin Microbiol Rev 21:505-18. 2008..Such studies combined with better integration of host and pathogen research driven by epidemiological findings may truly advance our understanding of Campylobacter infection in humans...
- A role for Campylobacter jejuni-induced enteritis in inflammatory bowel disease?Lisa D Kalischuk
Agriculture and Agri Food Canada, Lethbridge, Canada
Am J Physiol Gastrointest Liver Physiol 298:G1-9. 2010....
- Campylobacter jejuni Infections: update on emerging issues and trendsB M Allos
Department of Preventive Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Clin Infect Dis 32:1201-6. 2001..jejuni infection, but its incidence is <1 per 1000 infections. Careful food preparation and cooking practices may prevent some Campylobacter infections.
- Campylobacter, from obscurity to celebrityJ P Butzler
Department of Human Ecology, Faculty of Medicine, Vrije Universiteit Brussel, Brussels, Belgium
Clin Microbiol Infect 10:868-76. 2004..jejuni remains susceptible to fluoroquinolones. The public health burden of Campylobacter spp. other than C. jejuni/C. coli remains unmeasured. Better diagnostic methods may reveal the true health burden of these organisms...
- Changes in causes of acute gastroenteritis in the United Kingdom over 15 years: microbiologic findings from 2 prospective, population-based studies of infectious intestinal diseaseClarence C Tam
Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
Clin Infect Dis 54:1275-86. 2012..We examined changes in etiology and diagnostic yield of IID cases over 15 years...
- Caecal transcriptome analysis of colonized and non-colonized chickens within two genetic lines that differ in caecal colonization by Campylobacter jejuniX Y Li
Department of Poultry Science, Texas A and M University, College Station, TX 77843, USA
Anim Genet 42:491-500. 2011..jejuni colonization and that the tumour necrosis factor receptor superfamily genes play important roles in determining C. jejuni non-colonization in broilers...
- The dioxin crisis as experiment to determine poultry-related campylobacter enteritisAkke Vellinga
Department of Epidemiology and Social Medicine, Institute of Public Health Louis Pasteur, Brussels, Belgium
Emerg Infect Dis 8:19-22. 2002..Through the sentinel surveillance system, a decrease in Campylobacter infections during June 1999 was noticed...
- Molecular-based detection of non-culturable and emerging campylobacteria in patients presenting with gastroenteritisS Bullman
Department of Biological Sciences, Cork Institute of Technology, Ireland
Epidemiol Infect 140:684-8. 2012..are responsible for a considerable proportion of human enteritis and the true incidence of infection is likely to be significantly underestimated where conventional Campylobacter culture methods are used in isolation...
- Allelic diversity and recombination in Campylobacter jejuniS Suerbaum
Institut fur Hygiene und Mikrobiologie der Universitat Wurzburg, D 97080 Wurzburg, Germany
J Bacteriol 183:2553-9. 2001..These analyses showed that intraspecific recombination is frequent in C. jejuni and has generated extensive diversity of allelic profiles from a small number of polymorphic nucleotides...
- Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseasesY Doorduyn
Department Epidemiology and Surveillance, Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Epidemiol Infect 136:1225-34. 2008We studied the role of host genetics in the susceptibility to severe Salmonella and Campylobacter infections and chronic sequelae of these infections...
- Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasionJoshua A Fields
Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1459 Laney Walker Blvd, Augusta, GA 30912, USA
J Bacteriol 190:3411-6. 2008..CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis...
- Isolation of motile and non-motile insertional mutants of Campylobacter jejuni: the role of motility in adherence and invasion of eukaryotic cellsR Yao
Enteric Diseases Program, Naval Medical Research Institute Annex, Rockville, Maryland 20852
Mol Microbiol 14:883-93. 1994..Characterization of the mutants at the molecular level and in animal models should further contribute to our understanding of the pathogenicity of these organisms...
- Influence of season and geography on Campylobacter jejuni and C. coli subtypes in housed broiler flocks reared in Great BritainF Jorgensen
Health Protection Agency, Microbiology Services, Food, Water and Environmental Microbiology Network, Porton Down, Salisbury SP4 0JG, United Kingdom
Appl Environ Microbiol 77:3741-8. 2011..Flocks slaughtered at the same time were more likely to have similar complexes, and ST-45 had a seasonal pattern, with the highest prevalence in June, and was also more likely to be present in flocks reared in northern Great Britain...
- Campylobacter colonization of the chicken induces a proinflammatory response in mucosal tissuesChristopher K Smith
Institute for Animal Health, Compton, Berkshire, UK
FEMS Immunol Med Microbiol 54:114-21. 2008..This correlated with an influx of heterophils but was not associated with any pathology. These results suggest that in poultry there may be a controlled inflammatory process during colonization...
- Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter sppSophie Payot
Institut National de la Recherche Agronomique, UR086 BioAgresseurs, santé, Environnement, Nouzilly, France
Microbes Infect 8:1967-71. 2006The incidence of human Campylobacter infections is increasing worldwide, as well as the proportion of isolates resistant to fluoroquinolones and/or macrolides, the drugs of choice to treat campylobacteriosis...
- A re-evaluation of the impact of temperature and climate change on foodborne illnessI R Lake
School of Environmental Sciences, University of East Anglia, Norwich, UK
Epidemiol Infect 137:1538-47. 2009..These adaptations to temperature imply that current estimates of how climate change may alter foodborne illness burden are overly pessimistic...
- Is the major increase in notified campylobacteriosis in New Zealand real?M G Baker
Department of Public Health, Wellington School of Medicine and Health Sciences, Otago University, Wellington, New Zealand
Epidemiol Infect 135:163-70. 2007..Given the large disease burden, further research and intervention studies should be public health priorities in this country...
- Quantifying transmission of Campylobacter spp. among broilersT J W M Van Gerwe
Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL Utrecht, The Netherlands
Appl Environ Microbiol 71:5765-70. 2005....
- Genetic diversity in Campylobacter jejuni is associated with differential colonization of broiler chickens and C57BL/6J IL10-deficient miceDavid L Wilson
National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 48823, USA
Microbiology 156:2046-57. 2010..jejuni; the enhancement of genetic diversity at this location may contribute to its importance as a human disease reservoir...
- Genetic diversity among Campylobacter jejuni isolates from pets in IrelandE Acke
School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
Vet Rec 166:102-6. 2010....
- Isolation and detection of Campylobacter concisus from saliva of healthy individuals and patients with inflammatory bowel diseaseLi Zhang
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, New South Wales 2052, Australia
J Clin Microbiol 48:2965-7. 2010..C. concisus was detected in 97% of the healthy individuals and 100% of the patients with IBD tested. The C. concisus culture positivity rate in younger children was significantly lower than that in the other age groups...
- Campylobacter concisus: an emerging pathogen?Diane G Newell
MED VET NET, Veterinary Laboratories Agency, Addlestone, Surrey, UK
Eur J Gastroenterol Hepatol 17:1013-4. 2005..However, considerable further work is needed with more discriminatory genotyping methods, before accurate assessment of the risk of C. concisus infection to human health can be determined...
- Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium-host interactionsBoy M Bachtiar
Biotechnology and Environmental Biology, RMIT University, Melbourne, Australia
FEMS Immunol Med Microbiol 49:149-54. 2007..jejuni capsular polysaccharides play an important role in adherence to and invasion of human embryonic epithelial cells. However, no significant role of capsular polysaccharides was shown in colonization of the chicken gut...
- Standing genetic variation in contingency loci drives the rapid adaptation of Campylobacter jejuni to a novel hostJohn P Jerome
Comparative Enteric Diseases Laboratory, Michigan State University, East Lansing, Michigan, United States of America
PLoS ONE 6:e16399. 2011..jejuni adaptation and virulence in a novel host...
- Guillain-Barré syndrome after exposure to influenza virusHelmar C Lehmann
Department of Neurology, Heinrich Heine University, Moorenstrasse 5, Dusseldorf, Germany
Lancet Infect Dis 10:643-51. 2010..However, the experiences from the 1976 swine flu vaccination programme emphasise the importance for active and passive surveillance to monitor vaccine safety...
- Association of antimicrobial resistance in Campylobacter isolated from food-producing animals with antimicrobial use on farmsTetsuo Asai
National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Tokyo 185 8511, Japan
Jpn J Infect Dis 60:290-4. 2007..1% (4/44) and 24.1% (14/58) of the farms where enrofloxacin-resistant C. jejuni and C. coli were isolated, respectively. It is likely that several factors account for the presence of fluoroquinolone-resistant Campylobacter...
- Colonization strategy of Campylobacter jejuni results in persistent infection of the chicken gutKim Van Deun
Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, Merelbeke, Belgium
Vet Microbiol 130:285-97. 2008..These findings suggest a novel colonization mechanism by escaping rapid mucosal clearance through short-term epithelial invasion and evasion, combined with fast replication in the mucus...
- Campylobacter in poultry: filling an ecological nicheMargie D Lee
Department of Population Health, Poultry Diagnostic and Research Center, The University of Georgia, Athens, GA 30602, USA
Avian Dis 50:1-9. 2006....
- Delineation of Campylobacter concisus genomospecies by amplified fragment length polymorphism analysis and correlation of results with clinical dataRune Aabenhus
Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark
J Clin Microbiol 43:5091-6. 2005..Campylobacter concisus is genetically and taxonomically diverse and contains at least four distinct genomospecies that may exhibit differences in their spectra of virulence potential...
- Characterization of the specific interaction between sialoadhesin and sialylated Campylobacter jejuni lipooligosaccharidesAstrid P Heikema
Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands
Infect Immun 78:3237-46. 2010....
- Quantitative risk assessment of human campylobacteriosis associated with thermophilic Campylobacter species in chickensHanne Rosenquist
The Danish Veterinary and Food Administration, Institute of Food Safety and Toxicology, Division of Microbiological Safety, 19, Mørkhøj Bygade, 2860 Søborg, Denmark
Int J Food Microbiol 83:87-103. 2003..Finally, the simulations showed that people in the age of 18-29 years had the highest risk of developing campylobacteriosis...
- Generation of Campylobacter jejuni genetic diversity in vivoPaulo de Boer
Institute for Animal Science and Health, Division of Infectious Diseases and Food Chain Quality, PO Box 65, 8200 AB Lelystad, The Netherlands
Mol Microbiol 44:351-9. 2002..Together, the data indicate unequivocally that interstrain genetic exchange as well as intragenomic alterations do occur in vivo during C. jejuni infection. These events probably explain the genome plasticity observed for this pathogen...
- Campylobacter jejuni proteins Cj0952c and Cj0951c affect chemotactic behaviour towards formic acid and are important for invasion of host cellsA Malik Tareen
University Medical Center Gottingen, Institute for Medical Microbiology, Kreuzbergring 57, 37075 Gottingen, Germany
Microbiology 156:3123-35. 2010..jejuni, (iv) alter the chemotactic behaviour of the pathogen towards formic acid, and (v) are not related to the utilization of formic acid by formate dehydrogenase...
- Antecedent infections in Fisher syndrome: a common pathogenesis of molecular mimicryM Koga
Department of Neurology, Dokkyo University School of Medicine, Shimotsuga, Tochigi, Japan
Neurology 64:1605-11. 2005..To assess the production mechanism of anti-GQ1b autoantibody in Fisher syndrome (FS)...
- The paternal effect of Campylobacter jejuni colonization in ceca in broilersX Li
Department of Poultry Science, Texas A and M University, College Station 77843, USA
Poult Sci 87:1742-7. 2008..jejuni counts in cloacal swabs and those in cecal contents. The results indicated that a paternal effect might be one of the important genetic factors influencing resistance to C. jejuni colonization in broilers...
- Incidence and ecology of Campylobacter jejuni and coli in animalsS M Horrocks
United States Department of Agriculture, Southern Plains Agricultural Research Center, College Station, TX 77845, USA
Anaerobe 15:18-25. 2009..Such multiple hurdle approaches that simultaneously utilize pre- and post-harvest control techniques are expected to be the most effective approach for decreasing human illness associated with foodborne pathogens...
- Attribution of Campylobacter infections in northeast Scotland to specific sources by use of multilocus sequence typingNorval J C Strachan
School of Biological Sciences, University of Aberdeen, Aberdeen, United Kingdom
J Infect Dis 199:1205-8. 2009..The results indicate that chicken is a major source of infection in young urban children, although not in their rural counterparts, for which ruminant and other avian sources are more important...
- Gamma-glutamyl transpeptidase has a role in the persistent colonization of the avian gut by Campylobacter jejuniIf H A Barnes
Veterinary Laboratories Agency Weybridge, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, UK
Microb Pathog 43:198-207. 2007..In vivo studies showed that, although GGT activity was not required for initial colonization of 1-day-old chicks, the enzyme was required for persistent colonization of the avian gut...
- Estimating community incidence of Salmonella, Campylobacter, and Shiga toxin-producing Escherichia coli infections, AustraliaGillian Hall
Australian National University, Acton, Australian Capital Territory, Australia
Emerg Infect Dis 14:1601-9. 2008..Estimation of multipliers allows assessment of the true effects of these diseases and better understanding of public health surveillance...
- Use of genome-wide expression profiling and mutagenesis to study the intestinal lifestyle of Campylobacter jejuniAlain Stintzi
Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
Infect Immun 73:1797-810. 2005..Overall, this study provides new insights on the mechanisms of gut colonization, as well as possible strategies employed by Campylobacter to resist or evade the host immune responses...
- Quinolone-resistant Campylobacter infections: risk factors and clinical consequencesJørgen Engberg
Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark
Emerg Infect Dis 10:1056-63. 2004..jejuni infections. An association between treatment with a fluoroquinolone before stool-specimen collection and having a quinolone-resistant C. jejuni infection was not observed...
- Rapid pulsed-field gel electrophoresis protocol for subtyping of Campylobacter jejuniE M Ribot
Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
J Clin Microbiol 39:1889-94. 2001..Comparison of PFGE patterns obtained in six laboratories showed that subtyping results obtained using this protocol are highly reproducible...
- Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuniDavid J McNally
Institute for Biological Sciences, National Research Council of Canada, 100 Sussex Drive, Ottawa, Ontario K1A 0R6, Canada
J Biol Chem 282:28566-76. 2007..These findings establish the importance of the MeOPN as a diagnostic marker and therapeutic target for C. jejuni and set the groundwork for future studies aimed at the detailed elucidation of the MeOPN biosynthetic pathway...
- Genome dynamics of Campylobacter jejuni in response to bacteriophage predationAndrew E Scott
Division of Food Sciences, University of Nottingham, Loughborough, United Kingdom
PLoS Pathog 3:e119. 2007..jejuni exists in vivo as families of related meta-genomes generated to survive local environmental pressures...
- The physiology of Campylobacter species and its relevance to their role as foodborne pathogensSimon F Park
School of Biomedical and Life Sciences, University of Surrey, Guildford, UK
Int J Food Microbiol 74:177-88. 2002..The aim of this review is to outline the unusual physiology of campylobacters (C. jejuni and C. coli) and to describe how this influences their role as foodborne pathogens...
- Macrolide resistance in Campylobacter jejuni and Campylobacter coliAmera Gibreel
Department of Medical Microbiology and Immunology, University of Alberta Edmonton, Alberta, Canada
J Antimicrob Chemother 58:243-55. 2006..Mechanisms implicated in macrolide resistance in C. jejuni and also techniques that have been developed for the efficient detection of macrolide-associated mutation(s) will be discussed in detail...
- Effect of Campylobacter-specific maternal antibodies on Campylobacter jejuni colonization in young chickensOrhan Sahin
Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio 44691, USA
Appl Environ Microbiol 69:5372-9. 2003....
- Fly transmission of CampylobacterGordon L Nichols
Environmental and Enteric Diseases Department, Communicable Disease Surveillance Centre, Health Protection Agency Centre for Infections, 61 Colindale Ave, London NW9 5EQ, UK
Emerg Infect Dis 11:361-4. 2005..The hypothesis provides an explanation for the seasonal distribution of Campylobacter infections seen around the world.
- Transmission of Campylobacter hyointestinalis from a pig to a humanGregor Gorkiewicz
Institute of Molecular Biology, Biochemistry and Microbiology, Karl Franzens University, Graz, Austria
J Clin Microbiol 40:2601-5. 2002..hyointestinalis strain originating from porcine feces. Subsequent typing of the human and the porcine isolates by pulsed-field gel electrophoresis revealed similar macrorestriction profiles, indicating transmission of this pathogen...
- Molecular epidemiology of Campylobacter jejuni in a geographically isolated country with a uniquely structured poultry industryPetra Mullner
Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Private Bag 11 222, Palmerston North, New Zealand
Appl Environ Microbiol 76:2145-54. 2010..jejuni has a distinctive molecular epidemiology in this country. These results may be due in part to New Zealand's geographical isolation and its uniquely structured poultry industry...
- Summary of the Swedish Campylobacter program in broilers, 2001 through 2005I Hansson
Department of Bacteriology, National Veterinary Institute, SE 751 89 Uppsala, Sweden
J Food Prot 70:2008-14. 2007..During the study period, about one-third of producers seldom delivered Campylobacter-positive batches (< 10% positive batches per year). Thus, it is possible to produce Campylobacter-free broilers in Sweden...
- Marked campylobacteriosis decline after interventions aimed at poultry, New ZealandAnn Sears
University of Otago, Wellington, New Zealand
Emerg Infect Dis 17:1007-15. 2011..contamination of poultry. The apparent success of these interventions may inform approaches other countries could consider to help control foodborne campylobacteriosis...
- Weather and notified Campylobacter infections in temperate and sub-tropical regions of Australia: an ecological studyPeng Bi
Discipline of Public Health, University of Adelaide, North Terrace, Adelaide, SA 5005, Australia
J Infect 57:317-23. 2008..This study was designed to quantify the relationship between weather variables and Campylobacter infections in two Australian cities with different local climatic conditions.
- Campylobacter jejuni--microtubule-dependent invasionD J Kopecko
Laboratory of Enteric and Sexually Transmitted Diseases, FDA Center for Biologics Evaluation and Research, Bldg 29 420, NIH Campus, Bethesda, MD 20892, USA
Trends Microbiol 9:389-96. 2001..current evidence suggests that C. jejuni use some markedly different molecular mechanisms of pathogenesis compared with shigellae...
- Campylobacter ureolyticus: an emerging gastrointestinal pathogen?Susan Bullman
Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
FEMS Immunol Med Microbiol 61:228-30. 2011..This is, to the best of our knowledge, the first report of C. ureolyticus in the faeces of patients presenting with gastroenteritis and may suggest a role for this organism as an emerging enteric pathogen...
- Outbreaks of campylobacteriosis in Australia, 2001 to 2006Leanne E Unicomb
National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australian Capital Territory, Australia
Foodborne Pathog Dis 6:1241-50. 2009..In addition to detection of chicken as a common source of outbreaks, these data highlight the importance of directing policy at commercial premises, aged care facilities, and school camps to reduce Campylobacter disease burden...
- Sequencing and validation of the genome of a Campylobacter concisus reveals intra-species diversityNandan P Deshpande
Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, New South Wales, Australia
PLoS ONE 6:e22170. 2011..Many of the observed differences are consistent with UNSWCD having adapted to greater surface interaction with host cells, as opposed to BAA-1457 which may prefer a free-living environment...
- Quantifying transmission of Campylobacter jejuni in commercial broiler flocksTwan van Gerwe
Department of Farm Animal Health, Utrecht University, The Netherlands
Appl Environ Microbiol 75:625-8. 2009..This study provides an important quantitative estimate of the rate of transmission of Campylobacter in broiler flocks, which could be helpful in future studies on the epidemiology of Campylobacter in the field...
- Identification of Campylobacter jejuni genes involved in its interaction with epithelial cellsVeronica Novik
Section of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Ave, New Haven, CT 06536, USA
Infect Immun 78:3540-53. 2010..jejuni entry and/or survival within host cells and a severe defect in colonization in an animal model. The implications of these findings for the understanding of C. jejuni-host cell interactions are discussed...
- Characterization and subgrouping of Campylobacter concisus strains using protein profiles, conventional biochemical testing and antibiotic susceptibilityRune Aabenhus
Department of Clinical Microbiology, National University Hospital Rigshospitalet, Denmark
Eur J Gastroenterol Hepatol 17:1019-24. 2005..To characterize and subgroup clinical strains of Campylobacter concisus isolated from patients with gastrointestinal disease...
- Multiple factors interact to produce responses resembling spectrum of human disease in Campylobacter jejuni infected C57BL/6 IL-10-/- miceJulia A Bell
Comparative Enteric Diseases Laboratory, National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA
BMC Microbiol 9:57. 2009..We took a comparative experimental approach to explore differences among different C. jejuni strains and studied the effect of diet on disease manifestation in an interleukin-10 deficient mouse model...
- First attempt to produce experimental Campylobacter concisus infection in miceRune Aabenhus
Department of Clinical Microbiology, National University Hospital Rigshospitalet, Copenhagen, Denmark
World J Gastroenterol 14:6954-9. 2008..To infect mice with atypical Campylobacter concisus (C. concisus) for the first time...
- Distribution of serotypes of Campylobacter jejuni and C. coli from Danish patients, poultry, cattle and swineE M Nielsen
Department of Microbiology, Danish Veterinary Laboratory, Copenhagen, Denmark
FEMS Immunol Med Microbiol 19:47-56. 1997..The serotype distribution of human clinical isolates showed large overlap with the serotype distribution of campylobacters in cattle and chickens, and on this basis both could be major sources of human campylobacteriosis...
- Multilocus sequence typing of Campylobacter jejuni isolates from humans, chickens, raw milk, and environmental water in Quebec, CanadaSimon Levesque
Department of Microbiology and Infectious Diseases, Faculté de Médecine de l Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, Quebec J1H 5N4, Canada
J Clin Microbiol 46:3404-11. 2008..Although MLST is labor-intensive and expensive, it remains the single best method for the genotyping of C. jejuni isolates and deciphering the epidemiologic relationships among isolates...
- A large multi-pathogen waterborne community outbreak linked to faecal contamination of a groundwater system, France, 2000A Gallay
Institut de Veille Sanitaire, Saint Maurice, France
Clin Microbiol Infect 12:561-70. 2006..This is the first documented waterborne outbreak of infection involving human C. coli infections. A better understanding of the factors influencing campylobacter transmission between hosts is required...
- Campylobacters as zoonotic pathogens: a food production perspectiveTom Humphrey
University of Bristol, Division of Veterinary Pathology, Infection and Immunity, School of Clinical Veterinary Sciences, The Churchill Building, Langford, Bristol BS40 5DU, United Kingdom
Int J Food Microbiol 117:237-57. 2007..There is also a need to better understand the reasons why campylobacters are capable of frequent change, particularly in the expression of surface antigens...
- Regulation of chicken contamination is urgently needed to control New Zealand's serious campylobacteriosis epidemicMichael Baker
Wellington School of Medicine and Health Sciences, University of Otago
N Z Med J 119:U2264. 2006....
- Tracing the source of campylobacteriosisDaniel J Wilson
Department of Maths and Statistics, Lancaster University, Lancaster, United Kingdom
PLoS Genet 4:e1000203. 2008..Our results imply that the primary transmission route is through the food chain, and suggest that incidence could be dramatically reduced by enhanced on-farm biosecurity or preventing food-borne transmission...
- Influence of Campylobacter jejuni fliA, rpoN and flgK genes on colonization of the chicken gutUrsla Fernando
Vaccine and Infectious Disease Organization, 120 Veterinary Road, Saskatoon, Saskatchewan, Canada S7N 5E3
Int J Food Microbiol 118:194-200. 2007..jejuni, is required for assembly of the flagellar secretory apparatus and an flgK mutant of C. jejuni expressing only the hook showed diminished motility and was completely attenuated for cecal colonization in chickens...
- Guillain-Barré syndrome and preceding infection with campylobacter, influenza and Epstein-Barr virus in the general practice research databaseClarence C Tam
Infectious Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 2:e344. 2007..A number of infectious agents have previously been suggested as risk factors for the development of Guillain-Barré syndrome (GBS), but robust epidemiologic evidence for these associations is lacking...
- Population-attributable risk estimates for risk factors associated with Campylobacter infection, australiaRussell J Stafford
Queensland Health, Brisbane, Queensland, Australia
Emerg Infect Dis 14:895-901. 2008..Our statistical technique could be applied more widely to other communicable diseases that are subject to routine surveillance...
- Campylobacter colonization and virulence determinantsAlain Stintzi; Fiscal Year: 2007..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
- Analysis of Campylobacter coli Lipooligosaccharide Core DiversityMARGARET KANIPES; Fiscal Year: 2006..A small but significant number of Campylobacter infections have also been linked to the development of Guillain Barre Syndrome (GBS)...
- 14th International CHRO WorkshopIrving Nachamkin; Fiscal Year: 2007..abstract_text> ..
- 13th International Campylobacter/Helicobacter workshopIrving Nachamkin; Fiscal Year: 2005..abstract_text> ..
- HOST FACTORS MEDIATE INVASION BY CAMPYLOBACTER JEJUNILINDA MANSFIELD; Fiscal Year: 2002..jejuni invasion is facilitated due to a direct effect of some secreted/excreted product of the worms, and 4) Determine what host cell genes are differentially expressed during C. jejuni invasion. ..
- Murine models to test parasite products as cures for Inflammatory Bowel DiseaseLINDA MANSFIELD; Fiscal Year: 2007..Dr. Mansfield has documented success mentoring graduate students and seeks to expand her mentoring of D.V.M.s in mouse pathobiology. ..
- Pathogenesis of Campylobacter enteritis:MICHAEL KONKEL; Fiscal Year: 2005..jejuni, and will be useful in the development of intervention and control methods to reduce the number of cases of human campylobacteriosis. ..
- Development and evaluation of subunit vaccine CmeC against Campylobacter jejuniJun Lin; Fiscal Year: 2007..for the development of alternative intervention strategies, such as vaccination, to prevent and control Campylobacter infections. Despite recent progress on the elucidation of immunogenic and protective antigens in C...
- Glycosylation of Campylobacter flagellaPatricia Guerry; Fiscal Year: 2007..The biological role of flagella glycosylation will be studied by examining a series of mutants in in vitro and in vivo assays of virulence. ..
- Capsule conjugate vaccines against ETEC and CampylobacterPatricia Guerry; Fiscal Year: 2010..Multiple conjugates could be combined into a multi-valent vaccine that would afford protection against the major antigenic variants of both pathogens. ..
- SIALYLATED SURFACE ANTIGENS OF CAMPYLOBACTER SPPPatricia Guerry; Fiscal Year: 2001..jejuni, MSC57360 and 81-176; and 3. Measure the virulence and immunogenicity of mutants of VC167, MSC, and 81-176 which are defective in post-translational modification genes and/or have non-sialylated LPS. ..
- Pandemic influenza control at the borders of island countries and in householdMichael Baker; Fiscal Year: 2007..Findings from the housing cohort would be used to guide advice about reducing influenza transmission in households, particularly in terms of crowding levels and exposure to active and passive smoking. ..
- Mechanisms of antibiotic efflux in CampylobacterQijing Zhang; Fiscal Year: 2010..The findings will also help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
- Mechanisms of antibiotic efflux in CampylobacterQijing Zhang; Fiscal Year: 2007..The findings will also help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
- Mechanisms of antibiotic efflux in CampylobacterQijing Zhang; Fiscal Year: 2007..The findings will help to identify potential molecular targets for the control and treatment of antibiotic resistant Campylobacter. ..
- Immunoglobulin Allotypes in Hepatitis C Virus InfectionJANARDAN PANDEY; Fiscal Year: 2007..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. ..
- Mechanisms of antibiotic efflux in CampylobacterQijing Zhang; Fiscal Year: 2005..jejuni and may open new avenues for the design of effective means to prevent and treat antibiotics-resistant Campylobacter. ..
- Gamma-Delta T cells and CryptosporidiosisBeth Kirkpatrick; Fiscal Year: 2007..These data will advance our understanding of the mucosal immune response to cryptosporidiosis, which will lead to further advances in prevention and therapy. ..
- Mechanisms of Interleukin-17 Inflammation Induced by Bacteroides fragilisCYNTHIA SEARS; Fiscal Year: 2009....
- PHYSIOLOGY AND CLONING OF B FRAGILIS ENTEROTOXINCYNTHIA SEARS; Fiscal Year: 2009..Our studies may indicate that a common stool bacterium is oncogenic and contributes to colon cancer risk. If so, these data will lead to new public health approaches to the prevention of colon cancer. ..
- Breast milk: Physiology, Biochemistry and OutcomesArdythe Morrow; Fiscal Year: 2006..A list of these publications is found on our society's website (www.isrhml.org.umu.se). ..
- Helicobacter induced hepatitis and tumorigenesisJames Fox; Fiscal Year: 2009..A more complete understanding of the etiopathogenesis of hepatobiliary disease and hepatocellular carcinoma is likely to result in new strategies for treatment and prevention of these important human diseases. ..
- Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants.Ardythe Morrow; Fiscal Year: 2009....
- Genetic Analysis of Campylobacter jejuni ColonizationDAVID HENDRIXSON; Fiscal Year: 2003..jejuni to identify genes required for chicken colonization. This last aim will allow us to begin to understand requirements of C. jejuni for colonization of a natural host. ..
- Campylobacter jejuni flagellar regulation and synthesisDAVID HENDRIXSON; Fiscal Year: 2009..The proposed research activities will determine how certain proteins of C.jejunifunction together to control production of flagellar proteins that make up the flagellar structure. ..
- Campylobacter jejuni flagellar regulation and synthesisDAVID HENDRIXSON; Fiscal Year: 2007..The proposed research activities will determine how certain proteins of C. jejuni function together to control production of flagellar proteins that make up the flagellar structure. ..
- Campylobacter jejuni flagellar regulation and synthesisDavid R Hendrixson; Fiscal Year: 2010..The proposed research activities will determine how certain proteins of C.jejunifunction together to control production of flagellar proteins that make up the flagellar structure. ..