campylobacter infections

Summary

Summary: Infections with bacteria of the genus CAMPYLOBACTER.

Top Publications

  1. ncbi Campylobacter jejuni: a brief overview on pathogenicity-associated factors and disease-mediating mechanisms
    Javid I Dasti
    Institute of Medical Microbiology, University Medical Centre Göttingen, Kreuzbergring 57, D 37075 Gottingen, Germany
    Int J Med Microbiol 300:205-11. 2010
  2. pmc Multilocus sequence typing system for Campylobacter jejuni
    K E Dingle
    Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford OX1 3FY, United Kingdom
    J Clin Microbiol 39:14-23. 2001
  3. pmc Prevalence of Campylobacter, Arcobacter, Helicobacter, and Sutterella spp. in human fecal samples as estimated by a reevaluation of isolation methods for Campylobacters
    J Engberg
    Department of Gastrointestinal Infections, Division of Diagnostics, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    J Clin Microbiol 38:286-91. 2000
  4. pmc Campylobacter genotyping to determine the source of human infection
    Samuel K Sheppard
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Clin Infect Dis 48:1072-8. 2009
  5. pmc Risk factors for campylobacteriosis of chicken, ruminant, and environmental origin: a combined case-control and source attribution analysis
    Lapo Mughini Gras
    Istituto Superiore di Sanita, Department of Veterinary Public Health and Food Safety, Rome, Italy
    PLoS ONE 7:e42599. 2012
  6. ncbi Campylobacters as zoonotic pathogens: a food production perspective
    Tom Humphrey
    University of Bristol, Division of Veterinary Pathology, Infection and Immunity, School of Clinical Veterinary Sciences, The Churchill Building, Langford, Bristol BS40 5DU, United Kingdom
    Int J Food Microbiol 117:237-57. 2007
  7. ncbi Campylobacter jejuni Infections: update on emerging issues and trends
    B M Allos
    Department of Preventive Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Clin Infect Dis 32:1201-6. 2001
  8. ncbi Campylobacter concisus: an evaluation of certain phenotypic and genotypic characteristics
    J Engberg
    Unit of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, Denmark
    Clin Microbiol Infect 11:288-95. 2005
  9. ncbi Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization
    Dirk Hofreuter
    Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA
    Cell Host Microbe 4:425-33. 2008
  10. pmc Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunity
    Stefan Bereswill
    Department of Microbiology and Hygiene, Charite University Medicine Berlin, Berlin, Germany
    PLoS ONE 6:e20953. 2011

Detail Information

Publications293 found, 100 shown here

  1. ncbi Campylobacter jejuni: a brief overview on pathogenicity-associated factors and disease-mediating mechanisms
    Javid I Dasti
    Institute of Medical Microbiology, University Medical Centre Göttingen, Kreuzbergring 57, D 37075 Gottingen, Germany
    Int J Med Microbiol 300:205-11. 2010
    ..Indeed, several lines of evidence suggest exploitation of different adaptation strategies by this pathogen depending on its requirement, whether to establish itself in the natural avian reservoir or during the course of human infection...
  2. pmc Multilocus sequence typing system for Campylobacter jejuni
    K E Dingle
    Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford OX1 3FY, United Kingdom
    J Clin Microbiol 39:14-23. 2001
    ..Application of this approach to further isolate collections will enable an integrated global picture of C. jejuni epidemiology to be established and will permit more detailed studies of the population genetics of this organism...
  3. pmc Prevalence of Campylobacter, Arcobacter, Helicobacter, and Sutterella spp. in human fecal samples as estimated by a reevaluation of isolation methods for Campylobacters
    J Engberg
    Department of Gastrointestinal Infections, Division of Diagnostics, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    J Clin Microbiol 38:286-91. 2000
    ..Further investigations to establish the role of C. concisus and S. wadsworthensis in enteric disease is needed. We conclude that a range of campylobacteria may cause infections in Denmark...
  4. pmc Campylobacter genotyping to determine the source of human infection
    Samuel K Sheppard
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Clin Infect Dis 48:1072-8. 2009
    ....
  5. pmc Risk factors for campylobacteriosis of chicken, ruminant, and environmental origin: a combined case-control and source attribution analysis
    Lapo Mughini Gras
    Istituto Superiore di Sanita, Department of Veterinary Public Health and Food Safety, Rome, Italy
    PLoS ONE 7:e42599. 2012
    ..Human Campylobacter infections can be attributed to specific reservoirs by estimating the extent of subtype sharing between strains from ..
  6. ncbi Campylobacters as zoonotic pathogens: a food production perspective
    Tom Humphrey
    University of Bristol, Division of Veterinary Pathology, Infection and Immunity, School of Clinical Veterinary Sciences, The Churchill Building, Langford, Bristol BS40 5DU, United Kingdom
    Int J Food Microbiol 117:237-57. 2007
    ..There is also a need to better understand the reasons why campylobacters are capable of frequent change, particularly in the expression of surface antigens...
  7. ncbi Campylobacter jejuni Infections: update on emerging issues and trends
    B M Allos
    Department of Preventive Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Clin Infect Dis 32:1201-6. 2001
    ..jejuni infection, but its incidence is <1 per 1000 infections. Careful food preparation and cooking practices may prevent some Campylobacter infections.
  8. ncbi Campylobacter concisus: an evaluation of certain phenotypic and genotypic characteristics
    J Engberg
    Unit of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, Denmark
    Clin Microbiol Infect 11:288-95. 2005
    ..Further evidence is needed to support the possible role of C. concisus as a human enteric pathogen...
  9. ncbi Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization
    Dirk Hofreuter
    Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA
    Cell Host Microbe 4:425-33. 2008
    ..In addition, these studies revealed remarkably specific nutritional requirements for a pathogen to effectively colonize different tissues...
  10. pmc Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunity
    Stefan Bereswill
    Department of Microbiology and Hygiene, Charite University Medicine Berlin, Berlin, Germany
    PLoS ONE 6:e20953. 2011
    ..Detailed investigation of C. jejuni-mediated intestinal immunopathology is hampered by the lack of appropriate vertebrate models. In particular, mice display colonization resistance against this pathogen...
  11. ncbi Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control study
    Y Doorduyn
    Epidemiology and Surveillance Unit, Netherlands Centre for Infectious Disease Control, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Epidemiol Infect 138:1391-404. 2010
    ..jejuni infections. This study illustrates that important differences in risk factors exist for different Campylobacter spp. and these may differ dependent on age, season or degree of urbanization...
  12. pmc L-fucose utilization provides Campylobacter jejuni with a competitive advantage
    Martin Stahl
    Department of Biochemistry, Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada
    Proc Natl Acad Sci U S A 108:7194-9. 2011
    ..This identifies a previously unrecorded metabolic pathway in select strains of C. jejuni associated with a virulent lifestyle...
  13. ncbi Characterization of a haemolytic phospholipase A(2) activity in clinical isolates of Campylobacter concisus
    Taghrid S Istivan
    Department of Biotechnology and Environmental Biology, RMIT University, PO Box 71, Bundoora, Victoria 3083, Australia
    J Med Microbiol 53:483-93. 2004
    ..concisus. The detection of haemolytic PLA(2) activity in C. concisus indicates the presence of a potential virulence factor in this species and supports the hypothesis that C. concisus is a possible opportunistic pathogen...
  14. ncbi Prevalence of Campylobacter concisus in diarrhoea of immunocompromised patients
    Rune Aabenhus
    Department of Infectious Diseases, National University Hospital, Copenhagen, Denmark
    Scand J Infect Dis 34:248-52. 2002
    ..C. concisus may be a frequent cause of diarrhoea in immunocompromised patients. Two groups of C. concisus were found and these groups possibly vary in their pathogenic potential...
  15. ncbi Campylobacter jejuni: molecular biology and pathogenesis
    Kathryn T Young
    Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nat Rev Microbiol 5:665-79. 2007
    ..Comparing the different host responses to C. jejuni colonization should increase our understanding of this organism...
  16. pmc Identification of Campylobacter jejuni genes involved in its interaction with epithelial cells
    Veronica Novik
    Section of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Ave, New Haven, CT 06536, USA
    Infect Immun 78:3540-53. 2010
    ..jejuni entry and/or survival within host cells and a severe defect in colonization in an animal model. The implications of these findings for the understanding of C. jejuni-host cell interactions are discussed...
  17. pmc Campylobacter jejuni--an emerging foodborne pathogen
    S F Altekruse
    U S Food and Drug Administration, Blacksburg, Virginia, USA
    Emerg Infect Dis 5:28-35. 1999
    ..Mishandling of raw poultry and consumption of undercooked poultry are the major risk factors for human campylobacteriosis. Efforts to prevent human illness are needed throughout each link in the food chain...
  18. pmc Host association of Campylobacter genotypes transcends geographic variation
    Samuel K Sheppard
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Appl Environ Microbiol 76:5269-77. 2010
    ..These findings are consistent with local and international transmission of host-associated lineages among food animal species and provide a foundation for further improvements in genetic attribution...
  19. ncbi Risk factors for sporadic Campylobacter infection in the United States: A case-control study in FoodNet sites
    Cindy R Friedman
    Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Infect Dis 38:S285-96. 2004
    ..During a 12-month study, we enrolled 1316 patients with culture-confirmed Campylobacter infections from 7 states, collecting demographic, clinical, and exposure data using a standardized questionnaire...
  20. pmc Campylobacter capsule and lipooligosaccharide confer resistance to serum and cationic antimicrobials
    Thormika Keo
    Department of Microbiology, New York University School of Medicine, NY, USA
    Virulence 2:30-40. 2011
    ....
  21. ncbi Source attribution of human campylobacteriosis using a meta-analysis of case-control studies of sporadic infections
    A R Domingues
    National Food Institute, Technical University of Denmark, Søborg, Denmark
    Epidemiol Infect 140:970-81. 2012
    ..Sub-analyses by geographical region, age group, and study period were performed, and differences were discussed...
  22. pmc Campylobacter jejuni colonization in wild birds: results from an infection experiment
    Jonas Waldenstrom
    Section for Zoonotic Ecology and Epidemiology, Linnaeus University, Kalmar, Sweden
    PLoS ONE 5:e9082. 2010
    ..In contrast, European Robins infected with the human isolate did not mount a significant response to bacterial membrane proteins from either of the two isolates. The difference in colonization ability could indicate host adaptations...
  23. ncbi Enteric Salmonella or Campylobacter infections and the risk of inflammatory bowel disease
    Tine Jess
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen S, Denmark
    Gut 60:318-24. 2011
    ....
  24. ncbi Assigning the source of human campylobacteriosis in New Zealand: a comparative genetic and epidemiological approach
    Petra Mullner
    Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand
    Infect Genet Evol 9:1311-9. 2009
    ..The comparative-modeling and molecular sentinel surveillance approach proposed in this study provides new opportunities for the management of zoonotic diseases...
  25. pmc Tracing the source of campylobacteriosis
    Daniel J Wilson
    Department of Maths and Statistics, Lancaster University, Lancaster, United Kingdom
    PLoS Genet 4:e1000203. 2008
    ..Our results imply that the primary transmission route is through the food chain, and suggest that incidence could be dramatically reduced by enhanced on-farm biosecurity or preventing food-borne transmission...
  26. ncbi The clinical importance of emerging Campylobacter species
    Si Ming Man
    Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK
    Nat Rev Gastroenterol Hepatol 8:669-85. 2011
    ..This Review presents the latest information on the role and clinical importance of emerging Campylobacter spp. in gastrointestinal health and disease...
  27. pmc Unique features of a highly pathogenic Campylobacter jejuni strain
    Dirk Hofreuter
    Section of Microbial Pathogenesis, School of Medicine, Yale University, New Haven, Connecticut 06536, USA
    Infect Immun 74:4694-707. 2006
    ..This information should help the understanding of the pathogenesis of C. jejuni and, in particular, the unique features of this highly pathogenic strain...
  28. ncbi Molecular mechanisms of campylobacter infection
    Jos P M van Putten
    Department of Infectious Diseases and Immunology, Utrecht University, Yalelaan 1, Utrecht, The Netherlands
    Curr Top Microbiol Immunol 337:197-229. 2009
    ..Novel experimental infection models suggest that the activation of the innate immune response is important for the development of intestinal pathology...
  29. pmc Detection and isolation of Campylobacter species other than C. jejuni from children with Crohn's disease
    Li Zhang
    School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia
    J Clin Microbiol 47:453-5. 2009
    ..concisus and higher levels of antibodies to C. concisus were detected in children with Crohn's disease (CD) than in controls. Campylobacter species other than C. jejuni were isolated from intestinal biopsy specimens of children with CD...
  30. ncbi Campylobacter flagella: not just for motility
    Patricia Guerry
    Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Ave, Silver Spring, MD 20910, USA
    Trends Microbiol 15:456-61. 2007
    ..Here, these recent advances in our understanding of the multifaceted role of flagella in Campylobacter virulence are summarized...
  31. pmc Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens
    C Loc Carrillo
    Division of Food Sciences, School of Biosciences, Sutton Bonington Campus, University of Nottingham, Loughborough LE12 5RD, United Kingdom
    Appl Environ Microbiol 71:6554-63. 2005
    ..The selection of appropriate phage and their dose optimization are key elements for the success of phage therapy to reduce campylobacters in broiler chickens...
  32. ncbi Campylobacter sugars sticking out
    Patricia Guerry
    Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Trends Microbiol 16:428-35. 2008
    ..The exciting surge in recent research activities will be summarized in this review...
  33. ncbi The role of respiratory donor enzymes in Campylobacter jejuni host colonization and physiology
    Dilan R Weerakoon
    Department of Microbiology, North Carolina State University, Raleigh, NC 27695, USA
    Microb Pathog 47:8-15. 2009
    ..jejuni are elucidated by chicken colonization assays, where the double mutant Hyd::Fdh, OorB::CM and nuo mutants are severely impaired in host colonization...
  34. pmc Epidemiological association of different Campylobacter jejuni groups with metabolism-associated genetic markers
    Andreas E Zautner
    Universitatsmedizin Gottingen, Abteilung für Medizinische Mikrobiologie, Kreuzbergring 57, D 37075 Gottingen, Germany
    Appl Environ Microbiol 77:2359-65. 2011
    ..In cases of C. jejuni outbreaks, these genetic markers could be helpful for more effective source tracking...
  35. pmc Iron acquisition and regulation in Campylobacter jejuni
    Kiran Palyada
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    J Bacteriol 186:4714-29. 2004
    ..Overall, this work documents the complex response of C. jejuni to iron availability, describes the genetic network between the Fur and iron regulons, and provides insight regarding the role of iron in C. jejuni colonization in vivo...
  36. ncbi Butyrate protects Caco-2 cells from Campylobacter jejuni invasion and translocation
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium
    Br J Nutr 100:480-4. 2008
    ..The present study showed that butyrate is able to protect Caco-2 cells from two major virulence mechanisms of C. jejuni, namely invasion and translocation, but not from a decline in transepithelial resistance...
  37. ncbi Immunity to Campylobacter: its role in risk assessment and epidemiology
    Arie H Havelaar
    Centre for Infectious Diseases Control Netherlands, National Institute for Public Health and the Environment, PO Box 1, 3720 BA Bilthoven, The Netherlands
    Crit Rev Microbiol 35:1-22. 2009
    ..in developed countries the highest incidence is observed in children under five years and the majority of Campylobacter infections are asymptomatic, which may be related to the effects of immunity and/or the ingested doses...
  38. pmc Molecular epidemiology of Campylobacter jejuni isolates from wild-bird fecal material in children's playgrounds
    Nigel P French
    Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand
    Appl Environ Microbiol 75:779-83. 2009
    ..jejuni isolates obtained in this study belonged to clonal complexes associated with wild-bird populations in the northern hemisphere and could have been introduced into New Zealand in imported wild garden birds in the 19th century...
  39. ncbi Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae
    Claudia Lupp
    Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
    Cell Host Microbe 2:204. 2007
    ..These findings underscore the importance of intestinal microbial ecosystems in infectious colitis and noninfectious intestinal inflammatory conditions,such as inflammatory bowel disease...
  40. ncbi Epidemiology of sporadic Campylobacter infection in the United States and declining trend in incidence, FoodNet 1996-1999
    Michael C Samuel
    California Emerging Infections Program, California Department of Health Services, Berkeley, CA 94704, USA
    Clin Infect Dis 38:S165-74. 2004
    ..Although the number of Campylobacter infections appears to have decreased in the United States during 1996-1999, the disease burden remains significant, ..
  41. pmc MUC1 cell surface mucin is a critical element of the mucosal barrier to infection
    Julie L McAuley
    Mucosal Diseases Program, Mater Medical Research Institute and The University of Queensland, South Brisbane, Queensland, Australia
    J Clin Invest 117:2313-24. 2007
    ....
  42. pmc Epidermal growth factor inhibits Campylobacter jejuni-induced claudin-4 disruption, loss of epithelial barrier function, and Escherichia coli translocation
    Jennifer M Lamb-Rosteski
    Department of Biological Sciences, Inflammation Research Network, University of Calgary, 2500 University Dr N W, Calgary, Alberta T2N 1N4, Canada
    Infect Immun 76:3390-8. 2008
    ..These findings highlight EGF's ability to alter colonization of C. jejuni in the intestinal tract and to protect against pathogen-induced barrier defects...
  43. pmc Comparison of molecular typing methods useful for detecting clusters of Campylobacter jejuni and C. coli isolates through routine surveillance
    Clifford G Clark
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    J Clin Microbiol 50:798-809. 2012
    ..Similarly, comparing several different typing methods reveals a great deal about differences in how the methods group individuals within the population...
  44. ncbi Correlation between invasion of Caco-2 eukaryotic cells and colonization ability in the chick gut in Campylobacter jejuni
    I Hanel
    Federal Research Centre for Virus Diseases of Animals, Institute of Molecular Pathogenesis, Jena, Naumburger Str 96a, 07743 Jena, Germany
    Vet Microbiol 101:75-82. 2004
    ..The characterization of the flagellin gene of the used C. jejuni strains resulted in eight flaA types. There was no association between flaA type and invasion or colonization ability in the chick gut...
  45. ncbi Molecular and spatial epidemiology of human campylobacteriosis: source association and genotype-related risk factors
    P Mullner
    Molecular Epidemiology and Veterinary Public Health Laboratory, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand
    Epidemiol Infect 138:1372-83. 2010
    ..In particular young children in rural areas had a higher risk of infection with ruminant strains than their urban counterparts. These findings provide important information for the implementation of pathway-specific control strategies...
  46. pmc Host-pathogen interactions in Campylobacter infections: the host perspective
    Riny Janssen
    Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Clin Microbiol Rev 21:505-18. 2008
    ..Such studies combined with better integration of host and pathogen research driven by epidemiological findings may truly advance our understanding of Campylobacter infection in humans...
  47. pmc A case-control study of risk factors for sporadic campylobacter infections in Denmark
    J Neimann
    Danish Zoonosis Centre, Danish Veterinary Institute, Bulowsvej 27, DK 1790 Copenhagen V, Denmark
    Epidemiol Infect 130:353-66. 2003
    ..5). Seasonal and regional interaction was observed for several risk factors and the time elapsed from interviewing of cases to interviewing of controls seemed to influence the effect of certain seasonal dependent risk factors...
  48. pmc Seasonality in six enterically transmitted diseases and ambient temperature
    E N Naumova
    Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    Epidemiol Infect 135:281-92. 2007
    ..This highly relevant to disease surveillance approach can be used to generate and test hypotheses related to disease seasonality and potential routes of transmission with respect to environmental factors...
  49. pmc Longitudinal study of Finnish Campylobacter jejuni and C. coli isolates from humans, using multilocus sequence typing, including comparison with epidemiological data and isolates from poultry and cattle
    Rauni Kärenlampi
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, P O Box 66, FI 00014 University of Helsinki, Finland
    Appl Environ Microbiol 73:148-55. 2007
    ..In contrast, ST-53, ST-58, ST-61, and ST-883 were significantly associated with isolates from cattle. Further studies are needed to reveal the significance of the observed associations...
  50. ncbi Campylobacter jejuni proteins Cj0952c and Cj0951c affect chemotactic behaviour towards formic acid and are important for invasion of host cells
    A Malik Tareen
    University Medical Center Gottingen, Institute for Medical Microbiology, Kreuzbergring 57, 37075 Gottingen, Germany
    Microbiology 156:3123-35. 2010
    ..jejuni, (iv) alter the chemotactic behaviour of the pathogen towards formic acid, and (v) are not related to the utilization of formic acid by formate dehydrogenase...
  51. pmc Human campylobacteriosis in developing countries
    Akitoye O Coker
    Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Idi Araba, Lagos, Nigeria
    Emerg Infect Dis 8:237-44. 2002
    ..National surveillance programs and international collaborations are needed to address the substantial gaps in the knowledge about the epidemiology of campylobacteriosis in developing countries...
  52. ncbi Campylobacter concisus and other Campylobacter species in children with newly diagnosed Crohn's disease
    Si Ming Man
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia
    Inflamm Bowel Dis 16:1008-16. 2010
    ..To further investigate this issue we determined the prevalence of these organisms in pediatric patients newly diagnosed with CD...
  53. pmc Antibiotic resistance in Campylobacter: emergence, transmission and persistence
    Taradon Luangtongkum
    Department of Veterinary Microbiology and Preventive Medicine, 1116 Veterinary Medicine Complex, Iowa State University, Ames, IA 500111, USA
    Future Microbiol 4:189-200. 2009
    ..A future perspective on antibiotic resistance and potential approaches for the control of antibiotic-resistant Campylobacter, will also be discussed...
  54. ncbi Climate variability and campylobacter infection: an international study
    R Sari Kovats
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Int J Biometeorol 49:207-14. 2005
    ..The main driver of seasonality of campylobacter remains elusive and underscores the need to identify the major serotypes and routes of transmission for this disease...
  55. ncbi Incidence and ecology of Campylobacter jejuni and coli in animals
    S M Horrocks
    United States Department of Agriculture, Southern Plains Agricultural Research Center, College Station, TX 77845, USA
    Anaerobe 15:18-25. 2009
    ..Such multiple hurdle approaches that simultaneously utilize pre- and post-harvest control techniques are expected to be the most effective approach for decreasing human illness associated with foodborne pathogens...
  56. ncbi The health burden of Campylobacter infection and the impact of antimicrobial resistance: playing chicken
    Guillermo M Ruiz-Palacios
    Clin Infect Dis 44:701-3. 2007
  57. pmc Detection of Campylobacter concisus and other Campylobacter species in colonic biopsies from adults with ulcerative colitis
    Indrani Mukhopadhya
    Gastrointestinal Research Group, Division of Applied Medicine, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom
    PLoS ONE 6:e21490. 2011
    ..This study investigated the prevalence of Campylobacter species in colonic biopsy samples from adults with UC and healthy controls...
  58. pmc Colonization factors of Campylobacter jejuni in the chicken gut
    David Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Res 42:82. 2011
    ..jejuni identified to date. These factors may contribute to our understanding on how C. jejuni survival and colonization in chicks is mediated, as well as provide potential targets for effective subunit vaccine development...
  59. pmc Allelic diversity and recombination in Campylobacter jejuni
    S Suerbaum
    Institut fur Hygiene und Mikrobiologie der Universitat Wurzburg, D 97080 Wurzburg, Germany
    J Bacteriol 183:2553-9. 2001
    ..These analyses showed that intraspecific recombination is frequent in C. jejuni and has generated extensive diversity of allelic profiles from a small number of polymorphic nucleotides...
  60. pmc Attribution of Campylobacter infections in northeast Scotland to specific sources by use of multilocus sequence typing
    Norval J C Strachan
    School of Biological Sciences, University of Aberdeen, Aberdeen, United Kingdom
    J Infect Dis 199:1205-8. 2009
    ..The results indicate that chicken is a major source of infection in young urban children, although not in their rural counterparts, for which ruminant and other avian sources are more important...
  61. pmc Campylobacter jejuni survival within human epithelial cells is enhanced by the secreted protein CiaI
    Daelynn R Buelow
    School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 7520, USA
    Mol Microbiol 80:1296-312. 2011
    ..Based on the data, we conclude that CiaI contributes to the ability of C. jejuni to survive within epithelial cells...
  62. ncbi Poultry as a host for the zoonotic pathogen Campylobacter jejuni
    David Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Vector Borne Zoonotic Dis 12:89-98. 2012
    ..jejuni in broiler flocks. As a result, the number of human campylobacteriosis cases associated with the chicken vector remains strikingly high...
  63. ncbi The epidemiology of antibiotic resistance in Campylobacter
    John E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
    Microbes Infect 8:1955-66. 2006
    ....
  64. pmc Activation of human and chicken toll-like receptors by Campylobacter spp
    Marcel R de Zoete
    Department of Infectious Diseases and Immunology, Utrecht University, P O Box 80 165, 3508 TD Utrecht, The Netherlands
    Infect Immun 78:1229-38. 2010
    ..The results suggest that differences in bacterial cell wall integrity and in TLR responses to Campylobacter LOS and/or DNA may contribute to the distinct clinical manifestation between the species...
  65. ncbi A role for Campylobacter jejuni-induced enteritis in inflammatory bowel disease?
    Lisa D Kalischuk
    Agriculture and Agri Food Canada, Lethbridge, Canada
    Am J Physiol Gastrointest Liver Physiol 298:G1-9. 2010
    ....
  66. pmc Wide geographical distribution of internationally rare Campylobacter clones within New Zealand
    S M McTavish
    ESR Ltd, Kenepuru Science Centre, Porirua, New Zealand
    Epidemiol Infect 136:1244-52. 2008
    ....
  67. ncbi Campylobacter, from obscurity to celebrity
    J P Butzler
    Department of Human Ecology, Faculty of Medicine, Vrije Universiteit Brussel, Brussels, Belgium
    Clin Microbiol Infect 10:868-76. 2004
    ..jejuni remains susceptible to fluoroquinolones. The public health burden of Campylobacter spp. other than C. jejuni/C. coli remains unmeasured. Better diagnostic methods may reveal the true health burden of these organisms...
  68. pmc The seasonality of human campylobacter infection and Campylobacter isolates from fresh, retail chicken in Wales
    R J Meldrum
    National Public Health Service for Wales, Cardiff, UK
    Epidemiol Infect 133:49-52. 2005
    Seasonal peaks in both human campylobacter infections and poultry isolates have been observed in several European countries but remain unexplained...
  69. ncbi Development of a multiplex PCR assay for identification of Campylobacter coli, Campylobacter fetus, Campylobacter hyointestinalis subsp. hyointestinalis, Campylobacter jejuni, Campylobacter lari and Campylobacter upsaliensis
    Wataru Yamazaki-Matsune
    Division of Bacteriology, Osaka Prefectural Institute of Public Health, Osaka, Japan
    J Med Microbiol 56:1467-73. 2007
    ....
  70. pmc Emergence of a tetracycline-resistant Campylobacter jejuni clone associated with outbreaks of ovine abortion in the United States
    Orhan Sahin
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa 50011, USA
    J Clin Microbiol 46:1663-71. 2008
    ..Together, these results indicate that a single tetracycline-resistant C. jejuni clone has emerged as the major cause of Campylobacter-associated sheep abortion in the United States...
  71. ncbi The Campylobacter jejuni stringent response controls specific stress survival and virulence-associated phenotypes
    Erin C Gaynor
    Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA
    Mol Microbiol 56:8-27. 2005
    ..jejuni stringent response in multiple aspects of C. jejuni biology and pathogenesis and, further, may lend novel insight into unexplored features of the stringent response in other prokaryotic organisms...
  72. ncbi Prevalence and antimicrobial resistance of Campylobacter isolates in broilers from China
    Xia Chen
    National Reference Laboratory for Veterinary Drug Residue, Key Laboratory of Development and Evaluation of the Chemical and Herbal Drugs for Animal Use, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People s Republic of China
    Vet Microbiol 144:133-9. 2010
    ....
  73. pmc Identification of a Campylobacter jejuni-secreted protein required for maximal invasion of host cells
    Jeffrey E Christensen
    Department of Microbiology, School of Molecular Biosciences, Washington State University, Pullman, Washington, USA
    Mol Microbiol 73:650-62. 2009
    ..Based on the phenotype of the C. jejuni Cj1242 mutant, we designated the protein Campylobacter invasion antigen C (CiaC). Collectively, our findings indicate that CiaC is a potentially important virulence factor...
  74. ncbi High incidence of Campylobacter concisus in gastroenteritis in North Jutland, Denmark: a population-based study
    H L Nielsen
    Department of Infectious Diseases, Aalborg Hospital, Aarhus University Hospital, Hobrovej 18 22, DK 9000 Aalborg, Denmark
    Clin Microbiol Infect 19:445-50. 2013
    ..Future studies have to focus on the clinical follow-up and the long-term risk of inflammatory bowel diseases in C. concisus-positive patients. We conclude that there is a high incidence of C. concisus in Denmark...
  75. ncbi Campylobacter-triggered reactive arthritis: a population-based study
    T Hannu
    Department of Medicine, Division of Rheumatology, Helsinki University Central Hospital, Finland
    Rheumatology (Oxford) 41:312-8. 2002
    ..To study the incidence and clinical picture of Campylobacter-associated reactive arthritis (ReA) and other reactive musculoskeletal symptoms in the population...
  76. pmc Identification of potential environmentally adapted Campylobacter jejuni strain, United Kingdom
    Will Sopwith
    Health Protection Agency, North West, Liverpool, UK
    Emerg Infect Dis 14:1769-73. 2008
    ..jejuni type in surface waters. ST-45 is likely more adapted to survival outside a host, making it a key driver of transmission between livestock, environmental, and human settings...
  77. pmc Sequence polymorphism, predicted secondary structures, and surface-exposed conformational epitopes of Campylobacter major outer membrane protein
    Q Zhang
    Food Animal Health Research Program, The Ohio State University, Wooster, Ohio 44691, USA
    Infect Immun 68:5679-89. 2000
    ..These findings are instrumental in the design of MOMP-based diagnostic tools and vaccines...
  78. ncbi Caecal transcriptome analysis of colonized and non-colonized chickens within two genetic lines that differ in caecal colonization by Campylobacter jejuni
    X Y Li
    Department of Poultry Science, Texas A and M University, College Station, TX 77843, USA
    Anim Genet 42:491-500. 2011
    ..jejuni colonization and that the tumour necrosis factor receptor superfamily genes play important roles in determining C. jejuni non-colonization in broilers...
  79. pmc The dioxin crisis as experiment to determine poultry-related campylobacter enteritis
    Akke Vellinga
    Department of Epidemiology and Social Medicine, Institute of Public Health Louis Pasteur, Brussels, Belgium
    Emerg Infect Dis 8:19-22. 2002
    ..Through the sentinel surveillance system, a decrease in Campylobacter infections during June 1999 was noticed...
  80. ncbi Changes in causes of acute gastroenteritis in the United Kingdom over 15 years: microbiologic findings from 2 prospective, population-based studies of infectious intestinal disease
    Clarence C Tam
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
    Clin Infect Dis 54:1275-86. 2012
    ..We examined changes in etiology and diagnostic yield of IID cases over 15 years...
  81. pmc Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasion
    Joshua A Fields
    Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1459 Laney Walker Blvd, Augusta, GA 30912, USA
    J Bacteriol 190:3411-6. 2008
    ..CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis...
  82. pmc Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases
    Y Doorduyn
    Department Epidemiology and Surveillance, Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Epidemiol Infect 136:1225-34. 2008
    We studied the role of host genetics in the susceptibility to severe Salmonella and Campylobacter infections and chronic sequelae of these infections...
  83. ncbi Molecular-based detection of non-culturable and emerging campylobacteria in patients presenting with gastroenteritis
    S Bullman
    Department of Biological Sciences, Cork Institute of Technology, Ireland
    Epidemiol Infect 140:684-8. 2012
    ..are responsible for a considerable proportion of human enteritis and the true incidence of infection is likely to be significantly underestimated where conventional Campylobacter culture methods are used in isolation...
  84. ncbi Campylobacter colonization of the chicken induces a proinflammatory response in mucosal tissues
    Christopher K Smith
    Institute for Animal Health, Compton, Berkshire, UK
    FEMS Immunol Med Microbiol 54:114-21. 2008
    ..This correlated with an influx of heterophils but was not associated with any pathology. These results suggest that in poultry there may be a controlled inflammatory process during colonization...
  85. ncbi Isolation of motile and non-motile insertional mutants of Campylobacter jejuni: the role of motility in adherence and invasion of eukaryotic cells
    R Yao
    Enteric Diseases Program, Naval Medical Research Institute Annex, Rockville, Maryland 20852
    Mol Microbiol 14:883-93. 1994
    ..Characterization of the mutants at the molecular level and in animal models should further contribute to our understanding of the pathogenicity of these organisms...
  86. ncbi Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter spp
    Sophie Payot
    Institut National de la Recherche Agronomique, UR086 BioAgresseurs, santé, Environnement, Nouzilly, France
    Microbes Infect 8:1967-71. 2006
    The incidence of human Campylobacter infections is increasing worldwide, as well as the proportion of isolates resistant to fluoroquinolones and/or macrolides, the drugs of choice to treat campylobacteriosis...
  87. pmc Influence of season and geography on Campylobacter jejuni and C. coli subtypes in housed broiler flocks reared in Great Britain
    F Jorgensen
    Health Protection Agency, Microbiology Services, Food, Water and Environmental Microbiology Network, Porton Down, Salisbury SP4 0JG, United Kingdom
    Appl Environ Microbiol 77:3741-8. 2011
    ..Flocks slaughtered at the same time were more likely to have similar complexes, and ST-45 had a seasonal pattern, with the highest prevalence in June, and was also more likely to be present in flocks reared in northern Great Britain...
  88. pmc Is the major increase in notified campylobacteriosis in New Zealand real?
    M G Baker
    Department of Public Health, Wellington School of Medicine and Health Sciences, Otago University, Wellington, New Zealand
    Epidemiol Infect 135:163-70. 2007
    ..Given the large disease burden, further research and intervention studies should be public health priorities in this country...
  89. pmc Quantifying transmission of Campylobacter spp. among broilers
    T J W M Van Gerwe
    Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL Utrecht, The Netherlands
    Appl Environ Microbiol 71:5765-70. 2005
    ....
  90. ncbi A re-evaluation of the impact of temperature and climate change on foodborne illness
    I R Lake
    School of Environmental Sciences, University of East Anglia, Norwich, UK
    Epidemiol Infect 137:1538-47. 2009
    ..These adaptations to temperature imply that current estimates of how climate change may alter foodborne illness burden are overly pessimistic...
  91. pmc Genetic diversity in Campylobacter jejuni is associated with differential colonization of broiler chickens and C57BL/6J IL10-deficient mice
    David L Wilson
    National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 48823, USA
    Microbiology 156:2046-57. 2010
    ..jejuni; the enhancement of genetic diversity at this location may contribute to its importance as a human disease reservoir...
  92. pmc Isolation and detection of Campylobacter concisus from saliva of healthy individuals and patients with inflammatory bowel disease
    Li Zhang
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, New South Wales 2052, Australia
    J Clin Microbiol 48:2965-7. 2010
    ..C. concisus was detected in 97% of the healthy individuals and 100% of the patients with IBD tested. The C. concisus culture positivity rate in younger children was significantly lower than that in the other age groups...
  93. ncbi Genetic diversity among Campylobacter jejuni isolates from pets in Ireland
    E Acke
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Rec 166:102-6. 2010
    ....
  94. ncbi Campylobacter concisus: an emerging pathogen?
    Diane G Newell
    MED VET NET, Veterinary Laboratories Agency, Addlestone, Surrey, UK
    Eur J Gastroenterol Hepatol 17:1013-4. 2005
    ..However, considerable further work is needed with more discriminatory genotyping methods, before accurate assessment of the risk of C. concisus infection to human health can be determined...
  95. ncbi Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium-host interactions
    Boy M Bachtiar
    Biotechnology and Environmental Biology, RMIT University, Melbourne, Australia
    FEMS Immunol Med Microbiol 49:149-54. 2007
    ..jejuni capsular polysaccharides play an important role in adherence to and invasion of human embryonic epithelial cells. However, no significant role of capsular polysaccharides was shown in colonization of the chicken gut...
  96. ncbi Campylobacter in poultry: filling an ecological niche
    Margie D Lee
    Department of Population Health, Poultry Diagnostic and Research Center, The University of Georgia, Athens, GA 30602, USA
    Avian Dis 50:1-9. 2006
    ....
  97. pmc Standing genetic variation in contingency loci drives the rapid adaptation of Campylobacter jejuni to a novel host
    John P Jerome
    Comparative Enteric Diseases Laboratory, Michigan State University, East Lansing, Michigan, United States of America
    PLoS ONE 6:e16399. 2011
    ..jejuni adaptation and virulence in a novel host...
  98. ncbi Association of antimicrobial resistance in Campylobacter isolated from food-producing animals with antimicrobial use on farms
    Tetsuo Asai
    National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Tokyo 185 8511, Japan
    Jpn J Infect Dis 60:290-4. 2007
    ..1% (4/44) and 24.1% (14/58) of the farms where enrofloxacin-resistant C. jejuni and C. coli were isolated, respectively. It is likely that several factors account for the presence of fluoroquinolone-resistant Campylobacter...
  99. ncbi Colonization strategy of Campylobacter jejuni results in persistent infection of the chicken gut
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Vet Microbiol 130:285-97. 2008
    ..These findings suggest a novel colonization mechanism by escaping rapid mucosal clearance through short-term epithelial invasion and evasion, combined with fast replication in the mucus...
  100. ncbi Guillain-Barré syndrome after exposure to influenza virus
    Helmar C Lehmann
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, Dusseldorf, Germany
    Lancet Infect Dis 10:643-51. 2010
    ..However, the experiences from the 1976 swine flu vaccination programme emphasise the importance for active and passive surveillance to monitor vaccine safety...
  101. ncbi Generation of Campylobacter jejuni genetic diversity in vivo
    Paulo de Boer
    Institute for Animal Science and Health, Division of Infectious Diseases and Food Chain Quality, PO Box 65, 8200 AB Lelystad, The Netherlands
    Mol Microbiol 44:351-9. 2002
    ..Together, the data indicate unequivocally that interstrain genetic exchange as well as intragenomic alterations do occur in vivo during C. jejuni infection. These events probably explain the genome plasticity observed for this pathogen...

Research Grants35

  1. Environmental Health Specialist Network
    RICHARD NORMAN DANILA; Fiscal Year: 2013
    ..Special studies to identify the burden of Cryptosporidium, Shiga toxin-producing E. coli, and Campylobacter infections due to drinking water, along with practices, behaviors, or other risk factors that lead to sporadic ..
  2. Antimicrobial peptide resistance in Campylobacter jejuni
    Jun Lin; Fiscal Year: 2010
    ..Contaminated poultry meats are considered a significant source for human Campylobacter infections. Increasing resistance of C...
  3. Ferric enterobactin acquisition systems in Campylobacter
    Jun Lin; Fiscal Year: 2011
    ..threat to public health and raises an urgent need for alternative strategies to prevent and control Campylobacter infections. Iron acquisition is essential for survival and colonization of pathogenic bacteria in the host and thus ..
  4. Campylobacter colonization and virulence determinants
    Alain Stintzi; Fiscal Year: 2007
    ..The identification of these Campylobacter determinants could significantly contribute to the development of more effective methods to diagnose, manage and ultimately prevent Campylobacter infections.
  5. Analysis of Campylobacter coli Lipooligosaccharide Core Diversity
    MARGARET KANIPES; Fiscal Year: 2006
    ..A small but significant number of Campylobacter infections have also been linked to the development of Guillain Barre Syndrome (GBS)...
  6. 14th International CHRO Workshop
    Irving Nachamkin; Fiscal Year: 2007
    ..abstract_text> ..
  7. 13th International Campylobacter/Helicobacter workshop
    Irving Nachamkin; Fiscal Year: 2005
    ..abstract_text> ..
  8. HOST FACTORS MEDIATE INVASION BY CAMPYLOBACTER JEJUNI
    LINDA MANSFIELD; Fiscal Year: 2002
    ..jejuni invasion is facilitated due to a direct effect of some secreted/excreted product of the worms, and 4) Determine what host cell genes are differentially expressed during C. jejuni invasion. ..
  9. Pathogenesis of Campylobacter enteritis:
    MICHAEL KONKEL; Fiscal Year: 2005
    ..jejuni, and will be useful in the development of intervention and control methods to reduce the number of cases of human campylobacteriosis. ..
  10. Development and evaluation of subunit vaccine CmeC against Campylobacter jejuni
    Jun Lin; Fiscal Year: 2008
    ..for the development of alternative intervention strategies, such as vaccination, to prevent and control Campylobacter infections. Despite recent progress on the elucidation of immunogenic and protective antigens in C...
  11. CELL-SURFACE PROTEINS IN CAMPYLOBACTER FETUS VIRULENCE
    Martin Blaser; Fiscal Year: 2004
    ..Finally, the data generated can be used to develop a mathematical model of antigenic variation that focuses on the relationship between microbial recombination generating diversity and host selection determining the direction of change. ..
  12. H PYLORI RECOMBINATION AND GASTRIC COLONIZATION
    Martin Blaser; Fiscal Year: 2001
    ..pylori infections. ..
  13. Development of furanones for treatment of anthrax
    Martin Blaser; Fiscal Year: 2005
    ..In initial studies, spores will be given subcutaneosly. Efficacy parameters will be defined as above. Successful trials can lead to phase I studies in humans, and treatment studies in non-human primates. ..
  14. Glycosylation of Campylobacter flagella
    Patricia Guerry; Fiscal Year: 2007
    ..The biological role of flagella glycosylation will be studied by examining a series of mutants in in vitro and in vivo assays of virulence. ..
  15. Pandemic influenza control at the borders of island countries and in household
    Michael Baker; Fiscal Year: 2008
    ..Findings from the housing cohort would be used to guide advice about reducing influenza transmission in households, particularly in terms of crowding levels and exposure to active and passive smoking. ..
  16. Gamma-Delta T cells and Cryptosporidiosis
    Beth Kirkpatrick; Fiscal Year: 2008
    ..These data will advance our understanding of the mucosal immune response to cryptosporidiosis, which will lead to further advances in prevention and therapy. ..
  17. Immunoglobulin Allotypes in Hepatitis C Virus Infection
    JANARDAN PANDEY; Fiscal Year: 2008
    ..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. ..
  18. PHYSIOLOGY AND CLONING OF B FRAGILIS ENTEROTOXIN
    CYNTHIA SEARS; Fiscal Year: 2010
    ..Our studies may indicate that a common stool bacterium is oncogenic and contributes to colon cancer risk. If so, these data will lead to new public health approaches to the prevention of colon cancer. ..
  19. HUS Pathogenesis & clinical Outcome in an in vivo model
    James Fox; Fiscal Year: 2008
    ..We will use this model to study the pathogenesis of HUS and importantly to develop therapeutic regimens to prevent and treat EHEC disease. [unreadable] [unreadable] [unreadable] [unreadable]..
  20. IN VIVO PATHOGENESIS OF HELICOBACTER PYLORI
    James Fox; Fiscal Year: 2009
    ..pylori pathogenesis and specifically evaluate the role of regulatory T cells in limiting H. pylori-induced gastric pathology. ..
  21. Neurocircuitry of Illness Induced Behavioral Depression
    LISA GOEHLER; Fiscal Year: 2009
    ....
  22. Probiotics in Pediatric Diarrhea in Peru
    Richard Oberhelman; Fiscal Year: 2008
    ....
  23. PROBIOTICS IN PEDIATRIC DIARRHEA IN PERU: PLANNING GRANT
    Richard Oberhelman; Fiscal Year: 2006
    ..Support for these activities during a planning period before the clinical trial will greatly facilitate the implementation of the trial. ..
  24. Neural and Immune Cell Interactions: Two of a Kind
    LISA GOEHLER; Fiscal Year: 2002
    ..Finally, the interactions between immune and neural cells may well be bi-directional, providing a novel mechanism by which neural activity can modulate immune cell functions. ..
  25. EXPERIMENTAL PATHOLOGY SHARED RESOURCE LABORATORY
    Laura Lamps; Fiscal Year: 2003
    ..abstract_text> ..
  26. Pathogen of Enterotoxigenic Bacteriodes Fragilis Infect
    CYNTHIA SEARS; Fiscal Year: 2003
    ..We hypothesize that ETBF is an under-recognized intestinal pathogen accounting for a portion of previously undiagnosed inflammatory intestinal infections in both children and adults. ..
  27. Microecology-murine gut-initiation & progression of IBD
    James Fox; Fiscal Year: 2005
    ..prior and subsequent to oral vaccination with Helicobacter spp. antigens and mucosal adjuvants, elucidate how these vaccine strategies influence microflora dynamics and impact gut cytokine responses. ..
  28. DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
    James Fox; Fiscal Year: 2006
    ....
  29. Role of Chemotaxis in Campylobacter Colonization
    Christopher Chang; Fiscal Year: 2006
    ..3. Conduct a biochemical characterization of the central signaling pathway that controls Campylobacter chemotaxis. ..
  30. Gastroenteritis and Extreme Weather Events in Elderly
    Elena Naumova; Fiscal Year: 2006
    ..abstract_text> ..
  31. Practical Diagnostics for AIDS-Related Pediatric TB,Peru
    Richard Oberhelman; Fiscal Year: 2006
    ..These new diagnostic methods have tremendous potential to improve and simplify the diagnosis of pediatric tuberculosis in low-income countries with limited laboratory resources. ..
  32. Helicobacter induced hepatitis and tumorigenesis
    James Fox; Fiscal Year: 2009
    ..A more complete understanding of the etiopathogenesis of hepatobiliary disease and hepatocellular carcinoma is likely to result in new strategies for treatment and prevention of these important human diseases. ..
  33. Breast milk: Physiology, Biochemistry and Outcomes
    Ardythe Morrow; Fiscal Year: 2006
    ..A list of these publications is found on our society's website (www.isrhml.org.umu.se). [unreadable] [unreadable] [unreadable]..
  34. Genetic Analysis of Campylobacter jejuni Colonization
    DAVID HENDRIXSON; Fiscal Year: 2003
    ..jejuni to identify genes required for chicken colonization. This last aim will allow us to begin to understand requirements of C. jejuni for colonization of a natural host. ..