central nervous system bacterial infections
Summary: Bacterial infections of the brain, spinal cord, and meninges, including infections involving the perimeningeal spaces.
Publications113 found, 100 shown here
- Central nervous system infectionsZoran Rumboldt
Department of Radiology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA
Semin Roentgenol 42:62-91. 2007
- A child with neurobrucellosisA C Hesseling
Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Western Cape Province, South Africa
Ann Trop Paediatr 23:145-8. 2003..Nerve conduction studies confirmed a proximal radiculopathy. Awareness of the condition and performance of the appropriate tests will differentiate neurobrucellosis from other chronic central nervous system infections...
- Intracranial infection associated with preseptal and orbital cellulitis in the pediatric patientDorothy J Reynolds
Department of Ophthalmology, North Shore Long Island Jewish Health System, Great Neck, NY, USA
J AAPOS 7:413-7. 2003..To identify risk factors in children admitted with preseptal or orbital cellulitis with associated intracranial infection...
- Cranial bacterial infectionPhilip Anslow
Department of Neuroradiology, Racliffe Infirmary, Oxford, OX2 6HE, UK
Eur Radiol 14:E145-54. 2004..A series of cases is presented to illustrate the role of imaging in infective disease and to draw attention to diagnostic and management points of which radiologists should be aware...
- Primary Whipple's disease of the brain: characterization of the clinical syndrome and molecular diagnosisP K Panegyres
Neurodegenerative Disorders Research, Suite 33, 146 Mounts Bay Road, Perth WA 6000, Australia
QJM 99:609-23. 2006..Whipple's disease (WD) of the brain without evidence of systemic involvement is a rare illness that is difficult to recognize and potentially life-threatening...
- [Transverse myelitis associated with cat-scratch disease]Antoni Turon Estrada
Med Clin (Barc) 120:437. 2003
- Nocardiosis with brain abscess due to an unusual species, Nocardia transvalensisRebecca F Yorke
Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
Arch Pathol Lab Med 127:224-6. 2003..Familiarity with the epidemiology, pathologic findings, and clinical significance of this and other unusual Nocardia species may increase early identification and antibiotic susceptibility testing in cases of nocardial infection...
- Trends in encephalitis-associated deaths in the United StatesN Khetsuriani
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Atlanta, GA 30333, USA
Epidemiol Infect 135:583-91. 2007..HIV infection was largely responsible for the lack of overall decline in the considerable mortality associated with encephalitis in the United States during 1979-1998...
- Serial imaging changes of cerebral Whipple's disease: from onset to the endChangliang Yu
Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
J Neuroimaging 17:81-3. 2007..A case with multiple cerebral Whipple disease is reported. The neuroradiological evolution from multiple macrophagic encephalitis to diffuse cerebral infarct in this case is described...
- [Neurolisteriosis in adults: report of six clinical cases]Ronald Salamano
Instituto de Neurologia, Facultad de Medicina, Montevideo, Uruguay
Arq Neuropsiquiatr 63:1063-9. 2005..It presents most commonly as an acute meningitis, although it can present itself as cerebritis, brain stem encephalitis (rhomboencephalitis), and exceptionally as myelitis...
- Strategies for the management of bacterial brain abscessCheng Hsien Lu
Department of Neurology, Chang Gung Memorial Hospital Kaohsiung, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan
J Clin Neurosci 13:979-85. 2006....
- Spinal epidural abscess successfully treated with percutaneous, computed tomography-guided, needle aspiration and parenteral antibiotic therapy: case report and review of the literatureRong Kuo Lyu
Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan
Neurosurgery 51:509-12; discussion 512. 2002..We describe a case of a posterior spinal epidural abscess that was successfully treated with percutaneous, computed tomography-guided, needle aspiration and parenteral antibiotic therapy...
- Clinical and laboratory findings in neurobrucellosis: review of 31 casesMahboubeh Haji-Abdolbagi
Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Iran
Arch Iran Med 11:21-5. 2008....
- Risk factors for infections related to external ventricular drainageD Hoefnagel
Erasmus Medical Centre, Department of Neurosurgery, Rotterdam, The Netherlands
Acta Neurochir (Wien) 150:209-14; discussion 214. 2008..The major complication of this procedure is an EVD-related infection, i.e., meningitis or ventriculitis. The purpose of the present retrospective single centre study is to assess the possible causes of these infections...
- Spectra of central nervous system melioidosisKalai Arasu Muthusamy
University Laboratory of Physiology, Oxford University, Parks Road, Oxford OX1 3PT, United Kingdom
J Clin Neurosci 14:1213-5. 2007..All these patients underwent surgical drainage leading to bacteriological diagnosis as well as appropriate long-term antibiotic therapy. All had good recovery at 6 months after completion of treatment...
- Management of neurobrucellosis: an assessment of 11 casesHanefi Cem Gul
Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Hospital, Ankara, Turkey
Intern Med 47:995-1001. 2008..The central nervous system involvement of Brucellosis causes a hard to treat infection with multiple sequelae. The aim of this paper is to discuss the course of neurobrucellosis in response to therapy...
- A quadriplegic child with multiple brain abscesses: case report of neurobrucellosisZarrin Keihani-Douste
Department of Pediatrics, Imam Khomeini Hospital, Tehran University of Medical Sciences, Iran
Med Sci Monit 12:CS119-122. 2006..This report presents a child with spinal cord lesion with concomitant multiple brain abscesses caused by brucellosis...
- [Corpus callosum pathological lesions in computed tomography and magnetic resonance imaging]M Bekiesinska-Figatowska
Zakładu Diagnostyki Obrazowej Centralnego Szpitala Kolejowego i Centrum Medycznego Kształcenia Podyplomowego w Warszawie
Neurol Neurochir Pol 35:829-40. 2001..CT and MR images from the authors' own experience illustrate the material...
- External ventricular drain infection: the effect of a strict protocol on infection rates and a review of the literatureD Dasic
Department of Neurological Surgery, Radcliffe Infirmary, Oxford, UK
Br J Neurosurg 20:296-300. 2006..This study demonstrates that adherence to an evidence-based protocol for their insertion and management is associated with a significant reduction in the infection rate...
- Variable presentation of neurological melioidosis in Northeast ThailandDirek Limmathurotsakul
Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Am J Trop Med Hyg 77:118-20. 2007..The appropriate duration and choice of parenteral and oral antimicrobial therapy for neurologic melioidosis are also discussed...
- [Whipple disease and central nervous system]Pedro Abreu
Servico de Neurologia, Hospital de S Joao, Porto
Acta Med Port 18:199-208. 2005..We alert for the early diagnosis of WD in patients with exclusively neurological clinical pictures, sometimes with atypical or non-definitive diagnosis, because it is a potential treatable disease...
- [Case report: subdural hemorrhage in neurobrucellosis]Günay Tuncer Ertem
S B Ankara Eğitim ve Araştirma Hastanesi, Infeksiyon Hastaliklari ve Klinik Mikrobiyoloji Klinigi, Ankara
Mikrobiyol Bul 38:253-6. 2004..The case deserved presentation and discussion since it presented with subdural hemorrhage which is a rare complication of neurobrucellosis...
- Presence of Chlamydophila psittaci DNA in the central nervous system of a patient with status epilepticusGernot Walder
Institute of Hygiene and Social Medicine, University of Innsbruck, Austria
Scand J Infect Dis 35:71-3. 2003..Direct invasion of the central nervous system by Chlamydophila psittaci was confirmed by the demonstration of specific DNA in the patient's cerebrospinal fluid. The patient recovered slowly under administration of doxycycline...
- Intracranial infection due to non-typhoidal Salmonella: report of four casesR Bellamy
J Infect 44:207-8. 2002
- Cure of multiresistant Acinetobacter baumannii central nervous system infections with intraventricular or intrathecal colistin: case series and literature reviewJohn Ng
Department of Microbiology and Infectious Diseases, South Western Area Pathology Service, Liverpool, Sydney, New South Wales, Australia
J Antimicrob Chemother 58:1078-81. 2006..Colistin remains one of the few remaining treatment options for MRAB but has poor CNS penetration. We describe our experience with intraventricular or intrathecal colistin for this infection...
- Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistinAspasia Katragkou
J Clin Microbiol 43:4916-7. 2005
- Nocardiosis: a reviewMarcelo E Corti
Unit 10, Infectious Diseases, FJ Muñiz Hospital, Buenos Aires, Argentina
Int J Infect Dis 7:243-50. 2003..The treatment of nocardiosis also requires expertise. This report reviews the epidemiology, physiopathology, clinical manifestations, diagnosis and treatment of this aerobic bacterial disease...
- [Meningitis due to Streptococcus bovis biotype II. Clinical case and review of the literature]José Manuel Barragán-Casas
Enferm Infecc Microbiol Clin 20:537-8. 2002
- Central nervous system infections and epilepsyGagandeep Singh
Department of Neurology, Dayanand Medical College, Ludhiana, India
Epilepsia 49:1. 2008
- Problem pathogens: extra-intestinal complications of Salmonella enterica serotype Typhi infectionDavid B Huang
Center for Infectious Diseases, Baylor College of Medicine, Houston, Texas 77030, USA
Lancet Infect Dis 5:341-8. 2005..We describe the epidemiology, clinical manifestations, pathogenesis, and treatment of extra-intestinal S typhi infections...
- Central nervous system Lyme diseaseJohn J Halperin
Department of Neurology, North Shore University Hospital, Manhasset, NY 11030, USA
Curr Neurol Neurosci Rep 5:446-52. 2005..Several well-performed studies have clearly shown that prolonged antimicrobial treatment of "post-Lyme disease" is ineffective. Diagnosis and treatment of Lyme disease continue to improve...
- Obsessive-compulsive disorder following brain injury: a reviewBernardus R Coetzer
North Wales Brain Injury Service, Conwy and Denbighshire NHS Trust, Colwyn Bay Hospital, United Kingdom
Int J Psychiatry Med 34:363-77. 2004..However, the first onset of obsessions and compulsions following a brain injury has been described, but cognitive impairments can potentially color the presentation...
- Neuroimage: disseminated nocardiosisP K Sethi
Clin Neurol Neurosurg 110:98-100. 2008
- Molecular mechanisms of axonal damage in inflammatory central nervous system diseasesHarald Neumann
Neuroimmunology Unit, European Neuroscience Institute Göttingen, Gottingen, Germany
Curr Opin Neurol 16:267-73. 2003..Axonal injury has attracted considerable interest during the past few years because the degree of axonal damage appears to determine long-term clinical outcome...
- Glycoconjugates: roles in neural diseases caused by exogenous pathogensCara Lynne Schengrund
The Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, 17033, USA
CNS Neurol Disord Drug Targets 5:381-9. 2006....
- Expression of neurotrophic factors in cerebrospinal fluid and plasma of children with viral and bacterial meningoencephalitisA Chiaretti
Paediatric Intensive Care Unit, Catholic University Medical School, Rome, Italy
Acta Paediatr 93:1178-84. 2004....
- Glucocorticoids in central nervous system bacterial infectionP K Coyle
Department of Neurology, State University of New York at Stony Brook, 11794, USA
Arch Neurol 56:796-801. 1999To evaluate evidence-based data on adjunctive glucocorticoid therapy in central nervous system bacterial infections.
- Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitisLars Ove Brandenburg
Department of Anatomy and Cell Biology, RWTH Aachen University, Aachen, Germany
J Neuropathol Exp Neurol 67:1041-54. 2008..Together, these results suggest that cathelicidins produced by glia and other cells play an important part in the innate immune response against pathogens in central nervous system bacterial infections.
- An unusual case of neurobrucellosis presenting as demyelination disorderOmer Bektas
Division of Pediatric Neurology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey
Turk J Pediatr 55:210-3. 2013..Additionally, this case is the first in terms of involvement of the corpus callosum in neurobrucellosis. In this article, we present an unusual case of neurobrucellosis. ..
- Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitisAnneleen Notebaert
Department of Pediatric Neurology, Ghent University Hospital, Ghent, Belgium
Pediatr Neurol 48:135-8. 2013..In the article, previously reported patients with MERS type 2 lesions are reviewed...
- [MR imaging in the diagnosis of primary and secondary cerebral infections]K Krope
Radiologie, Universitat Tubingen
Rofo 185:539-45. 2013..Both specific MR sequences and imaging characteristics of major cerebral infections are addressed in this overview. Furthermore, limitations and pitfalls of the method are discussed...
- Evaluation of children with neurobrucellosisS Akbayram
Department of Pediatrics, Yuzuncu Yil University, Van, Turkey
Bratisl Lek Listy 113:424-30. 2012..Central nervous system involvement is a serious complication of brucellosis with a ratio of 4-11% of all patients. Aim: to describe our experience in diagnosis, treatment, and outcome of 25 pediatric patients with neurobrucellosis...
- Co-infection of HIV and tropical infectious agents that affect the nervous systemL Chimelli
Division of Pathology, National Institute of Cancer, Rua Cordeiro da Graça 156, Santo Cristo, Rio de Janeiro, RJ, CEP 20220 400, Brazil
Rev Neurol (Paris) 168:270-82. 2012..This article reviews some of the key diagnostic aspects of tropical infections associated with HIV infection...
- Neurobrucellosis: clinical and diagnostic featuresTumer Guven
Infectious Diseases and Clinical Microbiology Clinic, Ataturk Training and Research Hospital, Ankara, Turkey
Clin Infect Dis 56:1407-12. 2013..We describe the neurological involvement in brucellosis and revisited diagnostic criteria for neurobrucellosis...
- Neurologic complications of HIV-1 infection and its treatment in the era of antiretroviral therapySarah M Kranick
National Institutes of Health, Building 10, 6 5700, Bethesda, MD 20892, USA
Continuum (Minneap Minn) 18:1319-37. 2012..Additionally, as successful virologic control has extended the life span of patients with HIV infection, neurologists are called upon to manage long-term complications, such as neurocognitive disorders and peripheral neuropathy...
- Staphylococcus aureus brainstem abscess in a Brazilian Amazon man. Case reportde Nazareth Hermes
Department of Neurosurgery, Hospital Ophir Loyola, Belem, Para, Brazil
J Neurosurg Sci 55:383-5. 2011..This case reinforces the importance of an early suspicion of BSA in patients with unexplained fever and neurologic deficits, especially sixth and seventh cranial nerve lesions, to minimize permanent damage...
- Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control studyPaola Di Carlo
Department of Sciences for Health Promotion, University of Palermo, via del Vespro 133, Palermo I 90127, Italy
BMC Pediatr 11:108. 2011....
- Rapid eradication of Listeria monocytogenes by moxifloxacin in a murine model of central nervous system listeriosisSolène Grayo
Laboratoire de Listeria, Centre National de Référence des Listeria, World Health Organization Collaborating Centre for Foodborne Listeriosis, Institut Pasteur, Paris, France
Antimicrob Agents Chemother 52:3210-5. 2008..Our results indicate that moxifloxacin combines useful pharmacokinetic properties and rapid bactericidal activity and that it may be a valuable alternative for the treatment of CNS listeriosis...
- Spectrum of CNS disease caused by rapidly growing mycobacteriaNaasha J Talati
Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA
Lancet Infect Dis 8:390-8. 2008..Treatment requires a long course of two or more antibiotics that have the ability to penetrate the blood-brain barrier, and possibly of steroids as immunomodulatory agents, such as those used in tuberculous meningitis...
- Linezolid in postneurosurgical infectionsB Maure
Infection 36:82-3. 2008
- Bilingual aphasia due to spontaneous acute subdural haematoma from a ruptured intracranial infectious aneurysmGirish V Vajramani
Department of Neurosurgery, Wessex Neurological Centre, Southampton General Hospital, University of Southampton, Tremona Road, Southampton SO16 6YD, UK
Clin Neurol Neurosurg 110:823-7. 2008..The neurology of language in a bilingual is analysed and possible mechanisms discussed...
- Massive ascites as unique sign of shunt infection by Propionibacterium acnesNicola Montano
Institute of Neurosurgery, Catholic University, Rome
Br J Neurosurg 24:221-3. 2010..We report on a case of P. acnes shunt infection presenting with massive ascites as the unique sign of CSF infection. Shunt removal, antibiotic therapy and drenaige of ascites were performed with a rapid clinical recovery...
- Cerebellar abscesses in children: excision or aspiration?Paritosh Pandey
Department of Neurosurgery, National Institute of Mental Health and Neuro Sciences, Bangalore, Karnataka, India
J Neurosurg Pediatr 1:31-4. 2008..There is still no consensus on the standard approach to these lesions, and controversy persists over whether these lesions should be treated with primary excision or aspiration...
- Cerebrospinal fluid shunt infections in children over a 13-year period: anaerobic cultures and comparison of clinical signs of infection with Propionibacterium acnes and with other bacteriaKai Arnell
Department of Pediatric Surgery, Uppsala University Hospital, Uppsala, Sweden
J Neurosurg Pediatr 1:366-72. 2008....
- New diagnostic tools for central nervous system infectionWendy C Ziai
Curr Opin Neurol 21:338-41. 2008
- Bartonella-associated meningoradiculoneuritis and dermatitis or panniculitis in 3 dogsJ R Cross
Department of Small Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA
J Vet Intern Med 22:674-8. 2008
- Pathogenesis of septic encephalopathyPeter Pytel
Department of Pathology, University of Chicago, Chicago, Illinois 60637, USA
Curr Opin Neurol 22:283-7. 2009..Here, we review recent advances in our understanding of septic encephalopathy, from molecular mechanisms to behavioral alterations, from diagnostic tools to potential therapeutic agents...
- Alzheimer's disease and infection: do infectious agents contribute to progression of Alzheimer's disease?Kie Honjo
L C Campbell Cognitive Neurology Research Unit, Heart and Stroke Foundation Centre for Stroke Recovery, Section of Neurology, Department of Medicine, Sunnybrook Health Science Centre and University of Toronto, Toronto, Ontario, Canada
Alzheimers Dement 5:348-60. 2009..If this hypothesis holds true, early intervention against infection may delay or even prevent the future development of AD...
- Impact of intracranial pressure monitor prophylaxis on central nervous system infections and bacterial multi-drug resistanceNathaniel F Stoikes
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Surg Infect (Larchmt) 9:503-8. 2008..We tested the hypothesis that prophylactic antibiotics do not reduce the incidence of central nervous system (CNS) infections but instead are associated with the acquisition of multi-drug resistant (MDR) bacterial infections...
- Overview of neurobrucellosis: a pooled analysis of 187 casesHanefi Cem Gul
Department of Infectious Diseases and Clinical Microbiology, Gulhane Medical Academy, Ankara, Turkey
Int J Infect Dis 13:e339-43. 2009..5% with suitable antibiotics. Neurobrucellosis may mimic various pathologies. For this reason, a thorough evaluation of the patient with probable disease is crucial for an accurate diagnosis and proper management of the disease...
- Antibiotics-impregnated ventricular catheter versus systemic antibiotics for prevention of nosocomial CSF and non-CSF infections: a prospective randomised clinical trialGeorge K C Wong
Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
J Neurol Neurosurg Psychiatry 81:1064-7. 2010..This study aims to compare antibiotic impregnated catheters with conventional catheters coupled with systemic antibiotics...
- Central nervous system infection with Staphylococcus intermedius secondary to retrobulbar abscessation in a dogJames A C Oliver
Davies Veterinary Specialists, Manor Farm Business Park, Higham Gobion, Hertfordshire SG5 3HR, UK
Vet Ophthalmol 12:333-7. 2009....
- Concomitant presentation of a glioblastoma multiforme with superimposed abscessDavid H Jho
Neurosurgery Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
World Neurosurg 75:126-31; discussion 50-3. 2011..In the present report we evaluate the diagnosis and treatment of a glioblastoma multiforme with an intratumoral abscess...
- Emerging therapeutic options in fulminant invasive rhinocerebral mucormycosisKathrin Scheckenbach
Department of Otorhinolaryngology, Head and Neck Surgery, Heinrich Heine University Dusseldorf, Moorenstrasse 5, Dusseldorf, Germany
Auris Nasus Larynx 37:322-8. 2010..Due to the lack of typical clinical signs, diagnosis relies on histopathology. Therapy consists of the management of predisposing factors, radical surgical intervention and systemic antifungal therapy...
- [Bacterial infections of the central nervous system]M Klein
Neurologische Klinik und Poliklinik, Klinikum Grosshadern, Universitat Munchen, Marchioninistrasse 15, Munich
Nervenarzt 81:150-61. 2010..Here, the relevant diagnostic and therapeutic aspects of three common bacterial infections of the central nervous system (neuroborreliosis, bacterial meningitis, and brain abscess) are discussed...
- Burden of neuroinfectious diseases on the neurology service in a tertiary care centerK Tan
Department of Neurology, 509 Pathology, 600 N Wolfe St, Baltimore, MD, USA
Neurology 71:1160-6. 2008..We aimed to determine the burden of neurologic infections on the neurology service in a tertiary care center and identify challenges in the diagnosis and treatment of these infections...
- NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogensVinita S Chauhan
Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, USA
Glia 57:414-23. 2009..As such, we have identified NOD2 as an important component in the generation of damaging CNS inflammation following bacterial infection...
- Secondary intracranial causes for headaches in childrenRooman Ahad
Department of Neurology, Division of Pediatric Neurology, Johns Hopkins Hospital, 200 N Wolfe Street, Baltimore, MD 21287, USA
Curr Pain Headache Rep 12:373-8. 2008..This article discusses these secondary causes of headaches due to primary brain etiologies, focusing on aspects of the history that should lead a neurologist to order neuroimaging or electroencephalographic studies for these children...
- The association between central nervous system (CNS) infections and epilepsy: epidemiological approaches and microbiological and epileptological perspectivesGagandeep Singh
Department of Neurology, Dayanand Medical College and Hospital, Ludhiana, India gagandeep
Epilepsia 49:2-7. 2008....
- Principles of antimicrobial therapyJEFFREY M TESSIER
Virginia Commonwealth University, Richmond, 23298 0049, USA
Handb Clin Neurol 96:17-29. 2010..g., improved symptoms, lack of new neurological findings) and radiographic changes (e.g., reduction in cavity size)...
- Neurobrucellosis: clinical, diagnostic, therapeutic features and outcome. Unusual clinical presentations in an endemic regionNurgul Ceran
Department of Infectious Diseases, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
Braz J Infect Dis 15:52-9. 2011..In inhabitants or visitors of endemic areas, neurobrucellosis should be kept in mind in cases that have unusual neurological manifestations...
- Obsessive-compulsive disorder after streptococcal infection in a frontal lobe-resected patientLucas C Quarantini
CNS Spectr 13:645-6. 2008
- [CNS infections in immunocompromised patients]K M Hartmann
Abt für Diagnostische und Interventionelle Neuroradiologie, Radiologische Klinik, Universitatsklinikum des Saarlandes, 66421, Homburg Saar
Radiologe 48:560-71. 2008..This article gives a review of the most frequent infective agents and image alterations. Modern radiology is not yet able to replace the gold standard of pathogen detection...
- Infections in the CNS during childhood and the risk of subsequent psychotic illness: a cohort study of more than one million Swedish subjectsChristina Dalman
Department of Psychiatric Epidemiology, EPI Karolinska Institutet, Norrbacka pl 5, 171 76 Stockholm, Sweden
Am J Psychiatry 165:59-65. 2008..The present study aims to investigate whether there is an increased risk of schizophrenia and other nonaffective psychoses associated with viral or bacterial CNS infections during childhood and, if so, which specific agents are involved...
- Whipple disease confined to the central nervous system presenting as a solitary frontal tumor. Case reportMario Löhr
Department of Neurosurgery, University of Cologne, Germany
J Neurosurg 101:336-9. 2004..A review of diagnostic and therapeutic options in suspected cases is presented...
- Isolated intracranial hypertension: a rare presentation of neurobrucellosisHandan Isin Ozisik
Research Hospital, Turgut Ozal Medical Center, Inonu University Medical Faculty, TR 44330 Malatya, Turkey
Microbes Infect 6:861-3. 2004..This case demonstrated that brucella meningitis may present with very slight symptoms, and inoculation of CSF into BACTEC bottle besides conventional cultures improves the detection of Brucella in endemic areas such as Turkey...
- Borrelia valaisiana in cerebrospinal fluidEudoxia Diza
Emerg Infect Dis 10:1692-3. 2004
- Diagnosis of bacterial cerebellitis: diffusion imaging and proton magnetic resonance spectroscopyRamandeep S Jaggi
Department of Neurosurgery, King George s Medical University, Lucknow, India
Pediatr Neurol 32:72-4. 2005..The child made a complete clinical and imaging recovery on conservative management...
- Defining bacterial meningitis and other infections of the central nervous systemGary D Overturf
Department of Pediatrics, University of New Mexico School of Medicine, Albuquerque, NM, USA
Pediatr Crit Care Med 6:S14-8. 2005..To define central nervous system infections of infants and children that occur as co-morbid or predisposing conditions of sepsis...
- Proton magnetic resonance spectroscopy and diffusion-weighted imaging of central nervous system whipple diseaseJared W Nelson
University of Iowa College of Medicine, Iowa City, IA 52246, USA
J Comput Assist Tomogr 29:320-2. 2005..Diffusion-weighted MRI and MRS offer noninvasive methods to help evaluate in vivo physiologic changes of CNS involvement in Whipple disease...
- MeropenemDheeraj Shah
Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi 110 095, India
Indian Pediatr 42:443-50. 2005..Due to concern relating to emergence of resistance, it should be used as a reserve drug in difficult-to-treat infections caused by resistant organisms or when conventional treatment fails...
- Clinical experience with linezolid for the treatment of central nervous system infectionsT A Rupprecht
Department of Neurology, Ludwig Maximilian University, Munich, Germany
Eur J Neurol 12:536-42. 2005..Linezolid appears to be a safe alternative to vancomycin for therapy-resistant CNS infections because of its good CSF penetration and few side-effects...
- A severe headacheBeau J Bagley
LSU Health Sciences Center and Children s Hospital, Department of Pediatrics, New Orleans, Louisiana 70118, USA
Clin Pediatr (Phila) 43:301-2. 2004
- Bug's lifeJohn McCrone
Lancet Neurol 2:710. 2003
- Immune reactions to Listeria monocytogenes in the brainD Schluter
Institut für Med Mikrobiologie und Hygiene, Universitat Heidelberg, Universitatsklinikum Mannheim, Germany
Immunobiology 201:188-95. 1999..The favorable prognosis of immunized mice correlated with a reduced intracerebral bacterial load, an increased recruitment of protective CD4+ and CD8+ T cells as well as an upregulated mRNA production of protective cytokines...
- Neurobrucellosis--a rare complication of renal transplantationB Yousif
Clinical Medical Services Department, Saudi Aramco-Dhahran Health Center, Saudi Aramco Medical Services Organization, Dhahran, Saudi Arabia
Am J Nephrol 21:66-8. 2001..Treatment with doxycycline and rifampin led to a clinical cure as well as to marked improvement in the Brucella titer...
- Effect of deficiency of tumor necrosis factor alpha or both of its receptors on Streptococcus pneumoniae central nervous system infection and peritonitisA Wellmer
Departments of Neurology, , , Germany
Infect Immun 69:6881-6. 2001..Early leukocyte influx into the peritoneum was impaired in TNF-alpha-deficient mice. The lack of TNF-alpha or its receptors renders mice more susceptible to S. pneumoniae infections...
- Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cellsYou hong Cui
Laboratory of Molecular Immunoregulation, Division of Basic Sciences, National Cancer Institute, Building 560, Frederick, MD 21702, USA
J Immunol 168:434-42. 2002..Thus, LPS selectively modulates the function of chemoattractant receptors in microglia and may promote host response in inflammatory diseases in the CNS...
- Intracranial Salmonella infections: meningitis, subdural collections and brain abscess. A series of six surgically managed cases with follow-up resultsAshok K Mahapatra
Department of Neurosurgery, The National Neurosurgical Centre, Khoula Hospital, Mina Al Fahal, Muscat, Sultanate of Oman
Pediatr Neurosurg 36:8-13. 2002..This study suggests that a high index of suspicion, early diagnosis and quick evacuation lead to success; this point is highlighted with the help of a review of the literature...
- Cerebellar abscess due to Listeria monocytogenesBassam M Addas
Department of Surgery, King Abdulaziz University Hospital, Riyadh, Kingdom of Saudi Arabia
Saudi Med J 23:226-8. 2002..The diagnosis of listeria monocytogenes was made in the surgical specimen. Our case illustrates the difficulty of early diagnosis of cerebellar listeria monocytogenes abscesses and the importance of prompt neurosurgical intervention...
- Chlamydia pneumoniae and multiple sclerosis: the latest etiologic candidateKhurram Bashir
Department of Neurology, University of Alabama at Birmingham, 220A Ryals Building, 1665 University Blvd, Birmingham, AL 35294 0022, USA
Epidemiology 14:133-4. 2003
- Community-acquired Klebsiella pneumoniae central nervous system infections in adults in SingaporeA G Habib
Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, 119074, Singapore, Singapore
Eur J Clin Microbiol Infect Dis 22:486-8. 2003....
- Invasive listeriosis in Denmark 1994-2003: a review of 299 cases with special emphasis on risk factors for mortalityP Gerner-Smidt
Danish Reference Centre for Listeriosis, Statens Serum Institut, Copenhagen, Denmark
Clin Microbiol Infect 11:618-24. 2005..The underlying conditions associated most strongly with mortality in the younger age group were non-haematological malignancies...
- A case of multiple cranial nerve palsy due to sphenoid sinusitis complicated by cerebral aneurysmNobuhiro Suzuki
Department of Otolaryngology, Tokyo Medical University, Shinjyuku ku, Nishishinjyuku, 6 7 1, Tokyo 160 0023, Japan
Auris Nasus Larynx 32:415-9. 2005..After endovascular coil placement, his right visual disturbance partially recovered...
- Treatment of neurobrucellosis: what is known and what remains to be answeredGeorgios Pappas
Institute of Continuing Medical Education of Ioannina, H, Trikoupi 10, Ioannina 45333, Greece
Expert Rev Anti Infect Ther 5:983-90. 2007..Treatment duration should be individualized in the absence of an adequate cut-off index...
- Isolated CNS Whipple disease with a variant of oculofacial-skeletal myorhythmia (OFSM)D Ciampi de Andrade
Department of Neurology, University of Sao Paulo, Brazil
Neurology 69:E12. 2007
- Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscessTammy Kielian
Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, Slot 846, Little Rock, AR 72205, USA
Am J Pathol 171:1199-214. 2007..disease models; however, its potential to influence the host immune response during central nervous system bacterial infections, such as brain abscess, has not yet been investigated...
- Extended subcutaneous tunnelling technique for external ventricular drainageG K K Leung
Division of Neurosurgery, Department of Surgery, Li Ka Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, SAR, China
Br J Neurosurg 21:359-64. 2007..However, this is essentially an audit within a single centre, and the findings should be interpreted with caution and with the understanding that individual institutions may have their unique patterns and risks of EVD infection...
- [GEIPC-SEIMC and GTEI-SEMICYUC recommendations for antibiotic treatment of gram positive coccal infections in the critical patient]P M Olaechea Astigarraga
Servicio de Medicina Intensiva, Hospital de Galdakao, Bo de Labeaga s n, 48960 Galdakao, Vizcaya, Spain
Med Intensiva 31:294-317. 2007....
- Subdural empyema caused by an unusual organism following intracranial haematomaPieter C Le Roux
Department of Paediatric Neurosurgery, Mater Children s Hospital, Brisbane, Queensland, Australia
Childs Nerv Syst 23:825-7. 2007..Subdural empyema is not commonly diagnosed in the developed world, occurring mostly after meningitis, sinusitis, trauma or surgery...
- External ventricular drain infections are independent of drain duration: an argument against elective revisionCheng H Lo
Department of Neurosurgery, The Alfred Hospital, Melbourne, Victoria, Australia
J Neurosurg 106:378-83. 2007....
- Ethanol, Tat and the Blood-brain barrierKwang Kim; Fiscal Year: 2004..e., nitric oxide and signaling pathways. The information derived from this proposal should enhance our understanding of the role of ethanol in HIV-1 neuropthogenesis. ..
- Monocyte Biology and BiodefenseDOUGLAS DREVETS; Fiscal Year: 2005..These data will then catalyze development of rational therapies to improve host defenses against severe and overwhelming infection by category A and B intracellular bacterial pathogens. ..
- HIV-1 protein neurotoxicity and ethanol pre-conditioningMichael Collins; Fiscal Year: 2006..abstract_text> ..
- Cryptococcus traversal of Brain Endothelial cellsKwang Kim; Fiscal Year: 2007..neoformans traversal of HBMEC monolayers and will be the basis of future investigations to characterize microbial-host interactions that are relevant to the pathogenesis of cryptococcal meningitis/meningoencephalitis. ..
- Effects of Neuroinflammation on Gap Junction Communication in GliaTammy Kielian; Fiscal Year: 2007..These experiments will provide meaningful insights into how proinflammatory mediators influence the extent of glial GJC in brain abscess. ..
- D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive DisorderEric Storch; Fiscal Year: 2007..Such agents may have utility in improving outcome, reducing premature therapy termination, and targeting patients who have been treatment refractory. ..
- Genome-wide screening of E. coli for bacteremiaKwang Kim; Fiscal Year: 2007..Further identification and characterization of microbial determinants contributing to E. coli bacteremia should help in development of preventive measures such as vaccines against E. coli bacteremia. ..
- E. coli invasion of brain endothelial cellsKwang Kim; Fiscal Year: 2007..3.To determine the role of K1 capsule in E. coli trafficking in HBMEC. Further understanding and characterization of E. coli K1-HBMEC interactions should allow us to develop novel strategies to prevent this serious infection. ..
- Research Training in Pediatric Infectious DiseasesKwang Kim; Fiscal Year: 2007..Based on our research program, resources, and track record, we request support for 2 postdoctoral training positions per year with a total of 6 postdoctoral positions (two each of first, second, and third year trainees). ..
- Receptors Involved in Microglial Responses to S. aureusTammy Kielian; Fiscal Year: 2007....
- Borrelia lipoproteins with the cerebral microcirculationDiego Cadavid; Fiscal Year: 2007..Determine whether Vspl crosses the BBB in vivo. 2. Investigate whether Vspl enters BMEC. 3. Determine whether Vspl crosses BMEC barriers. 4. Identify the structural features that mediate the interaction of Vspl with BMEC. ..
- GP 120 MEDIATED ACTIVATION OF BRAIN ENDOTHELIAL CELLSKwang Kim; Fiscal Year: 2002..e., roles of G proteins and signaling pathways, platelet-activating factor (PAF). The information derived from this proposal should enhance our understanding of the role of HBMEC in HIV encephalopathy. ..
- E. COLI BINDING TO BRAIN ENDOTHELIAL CELLSKwang Kim; Fiscal Year: 2003....
- E COLI INVASION OF BRAIN ENDOTHELIAL CELLSKwang Kim; Fiscal Year: 2003..Further understanding and characterization of these E. coli K1-BMEC interactions should allow us to develop novel strategies to prevent this serious infection. ..
- Leukotrienes and blood-brain barrierKwang S Kim; Fiscal Year: 2010..We propose to determine the contribution of the host molecules involving leukotrienes to microbial traversal of the blood-brain barrier. ..