central nervous system bacterial infections

Summary

Summary: Bacterial infections of the brain, spinal cord, and meninges, including infections involving the perimeningeal spaces.

Top Publications

  1. ncbi Central nervous system infections
    Zoran Rumboldt
    Department of Radiology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA
    Semin Roentgenol 42:62-91. 2007
  2. ncbi A child with neurobrucellosis
    A C Hesseling
    Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Western Cape Province, South Africa
    Ann Trop Paediatr 23:145-8. 2003
  3. ncbi Intracranial infection associated with preseptal and orbital cellulitis in the pediatric patient
    Dorothy J Reynolds
    Department of Ophthalmology, North Shore Long Island Jewish Health System, Great Neck, NY, USA
    J AAPOS 7:413-7. 2003
  4. ncbi Cranial bacterial infection
    Philip Anslow
    Department of Neuroradiology, Racliffe Infirmary, Oxford, OX2 6HE, UK
    Eur Radiol 14:E145-54. 2004
  5. ncbi Primary Whipple's disease of the brain: characterization of the clinical syndrome and molecular diagnosis
    P K Panegyres
    Neurodegenerative Disorders Research, Suite 33, 146 Mounts Bay Road, Perth WA 6000, Australia
    QJM 99:609-23. 2006
  6. ncbi Nocardiosis with brain abscess due to an unusual species, Nocardia transvalensis
    Rebecca F Yorke
    Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
    Arch Pathol Lab Med 127:224-6. 2003
  7. ncbi [Transverse myelitis associated with cat-scratch disease]
    Antoni Turon Estrada
    Med Clin (Barc) 120:437. 2003
  8. ncbi Management of neurobrucellosis: an assessment of 11 cases
    Hanefi Cem Gul
    Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Hospital, Ankara, Turkey
    Intern Med 47:995-1001. 2008
  9. ncbi Clinical and laboratory findings in neurobrucellosis: review of 31 cases
    Mahboubeh Haji-Abdolbagi
    Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 11:21-5. 2008
  10. ncbi Strategies for the management of bacterial brain abscess
    Cheng Hsien Lu
    Department of Neurology, Chang Gung Memorial Hospital Kaohsiung, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan
    J Clin Neurosci 13:979-85. 2006

Detail Information

Publications139 found, 100 shown here

  1. ncbi Central nervous system infections
    Zoran Rumboldt
    Department of Radiology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA
    Semin Roentgenol 42:62-91. 2007
  2. ncbi A child with neurobrucellosis
    A C Hesseling
    Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Western Cape Province, South Africa
    Ann Trop Paediatr 23:145-8. 2003
    ..Nerve conduction studies confirmed a proximal radiculopathy. Awareness of the condition and performance of the appropriate tests will differentiate neurobrucellosis from other chronic central nervous system infections...
  3. ncbi Intracranial infection associated with preseptal and orbital cellulitis in the pediatric patient
    Dorothy J Reynolds
    Department of Ophthalmology, North Shore Long Island Jewish Health System, Great Neck, NY, USA
    J AAPOS 7:413-7. 2003
    ..To identify risk factors in children admitted with preseptal or orbital cellulitis with associated intracranial infection...
  4. ncbi Cranial bacterial infection
    Philip Anslow
    Department of Neuroradiology, Racliffe Infirmary, Oxford, OX2 6HE, UK
    Eur Radiol 14:E145-54. 2004
    ..A series of cases is presented to illustrate the role of imaging in infective disease and to draw attention to diagnostic and management points of which radiologists should be aware...
  5. ncbi Primary Whipple's disease of the brain: characterization of the clinical syndrome and molecular diagnosis
    P K Panegyres
    Neurodegenerative Disorders Research, Suite 33, 146 Mounts Bay Road, Perth WA 6000, Australia
    QJM 99:609-23. 2006
    ..Whipple's disease (WD) of the brain without evidence of systemic involvement is a rare illness that is difficult to recognize and potentially life-threatening...
  6. ncbi Nocardiosis with brain abscess due to an unusual species, Nocardia transvalensis
    Rebecca F Yorke
    Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
    Arch Pathol Lab Med 127:224-6. 2003
    ..Familiarity with the epidemiology, pathologic findings, and clinical significance of this and other unusual Nocardia species may increase early identification and antibiotic susceptibility testing in cases of nocardial infection...
  7. ncbi [Transverse myelitis associated with cat-scratch disease]
    Antoni Turon Estrada
    Med Clin (Barc) 120:437. 2003
  8. ncbi Management of neurobrucellosis: an assessment of 11 cases
    Hanefi Cem Gul
    Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Hospital, Ankara, Turkey
    Intern Med 47:995-1001. 2008
    ..The central nervous system involvement of Brucellosis causes a hard to treat infection with multiple sequelae. The aim of this paper is to discuss the course of neurobrucellosis in response to therapy...
  9. ncbi Clinical and laboratory findings in neurobrucellosis: review of 31 cases
    Mahboubeh Haji-Abdolbagi
    Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 11:21-5. 2008
    ....
  10. ncbi Strategies for the management of bacterial brain abscess
    Cheng Hsien Lu
    Department of Neurology, Chang Gung Memorial Hospital Kaohsiung, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan
    J Clin Neurosci 13:979-85. 2006
    ....
  11. ncbi Spinal epidural abscess successfully treated with percutaneous, computed tomography-guided, needle aspiration and parenteral antibiotic therapy: case report and review of the literature
    Rong Kuo Lyu
    Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan
    Neurosurgery 51:509-12; discussion 512. 2002
    ..We describe a case of a posterior spinal epidural abscess that was successfully treated with percutaneous, computed tomography-guided, needle aspiration and parenteral antibiotic therapy...
  12. ncbi [Neurolisteriosis in adults: report of six clinical cases]
    Ronald Salamano
    Instituto de Neurologia, Facultad de Medicina, Montevideo, Uruguay
    Arq Neuropsiquiatr 63:1063-9. 2005
    ..It presents most commonly as an acute meningitis, although it can present itself as cerebritis, brain stem encephalitis (rhomboencephalitis), and exceptionally as myelitis...
  13. ncbi [Corpus callosum pathological lesions in computed tomography and magnetic resonance imaging]
    M Bekiesinska-Figatowska
    Zakładu Diagnostyki Obrazowej Centralnego Szpitala Kolejowego i Centrum Medycznego Kształcenia Podyplomowego w Warszawie
    Neurol Neurochir Pol 35:829-40. 2001
    ..CT and MR images from the authors' own experience illustrate the material...
  14. ncbi Serial imaging changes of cerebral Whipple's disease: from onset to the end
    Changliang Yu
    Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
    J Neuroimaging 17:81-3. 2007
    ..A case with multiple cerebral Whipple disease is reported. The neuroradiological evolution from multiple macrophagic encephalitis to diffuse cerebral infarct in this case is described...
  15. ncbi A quadriplegic child with multiple brain abscesses: case report of neurobrucellosis
    Zarrin Keihani-Douste
    Department of Pediatrics, Imam Khomeini Hospital, Tehran University of Medical Sciences, Iran
    Med Sci Monit 12:CS119-122. 2006
    ..This report presents a child with spinal cord lesion with concomitant multiple brain abscesses caused by brucellosis...
  16. pmc Trends in encephalitis-associated deaths in the United States
    N Khetsuriani
    Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Atlanta, GA 30333, USA
    Epidemiol Infect 135:583-91. 2007
    ..HIV infection was largely responsible for the lack of overall decline in the considerable mortality associated with encephalitis in the United States during 1979-1998...
  17. ncbi External ventricular drain infection: the effect of a strict protocol on infection rates and a review of the literature
    D Dasic
    Department of Neurological Surgery, Radcliffe Infirmary, Oxford, UK
    Br J Neurosurg 20:296-300. 2006
    ..This study demonstrates that adherence to an evidence-based protocol for their insertion and management is associated with a significant reduction in the infection rate...
  18. ncbi Variable presentation of neurological melioidosis in Northeast Thailand
    Direk Limmathurotsakul
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 77:118-20. 2007
    ..The appropriate duration and choice of parenteral and oral antimicrobial therapy for neurologic melioidosis are also discussed...
  19. ncbi [Whipple disease and central nervous system]
    Pedro Abreu
    Servico de Neurologia, Hospital de S Joao, Porto
    Acta Med Port 18:199-208. 2005
    ..We alert for the early diagnosis of WD in patients with exclusively neurological clinical pictures, sometimes with atypical or non-definitive diagnosis, because it is a potential treatable disease...
  20. ncbi Presence of Chlamydophila psittaci DNA in the central nervous system of a patient with status epilepticus
    Gernot Walder
    Institute of Hygiene and Social Medicine, University of Innsbruck, Austria
    Scand J Infect Dis 35:71-3. 2003
    ..Direct invasion of the central nervous system by Chlamydophila psittaci was confirmed by the demonstration of specific DNA in the patient's cerebrospinal fluid. The patient recovered slowly under administration of doxycycline...
  21. pmc Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistin
    Aspasia Katragkou
    J Clin Microbiol 43:4916-7. 2005
  22. ncbi Nocardiosis: a review
    Marcelo E Corti
    Unit 10, Infectious Diseases, FJ Muñiz Hospital, Buenos Aires, Argentina
    Int J Infect Dis 7:243-50. 2003
    ..The treatment of nocardiosis also requires expertise. This report reviews the epidemiology, physiopathology, clinical manifestations, diagnosis and treatment of this aerobic bacterial disease...
  23. ncbi [Meningitis due to Streptococcus bovis biotype II. Clinical case and review of the literature]
    José Manuel Barragán-Casas
    Enferm Infecc Microbiol Clin 20:537-8. 2002
  24. ncbi Problem pathogens: extra-intestinal complications of Salmonella enterica serotype Typhi infection
    David B Huang
    Center for Infectious Diseases, Baylor College of Medicine, Houston, Texas 77030, USA
    Lancet Infect Dis 5:341-8. 2005
    ..We describe the epidemiology, clinical manifestations, pathogenesis, and treatment of extra-intestinal S typhi infections...
  25. doi Central nervous system infections and epilepsy
    Gagandeep Singh
    Department of Neurology, Dayanand Medical College, Ludhiana, India
    Epilepsia 49:1. 2008
  26. ncbi Central nervous system Lyme disease
    John J Halperin
    Department of Neurology, North Shore University Hospital, Manhasset, NY 11030, USA
    Curr Neurol Neurosci Rep 5:446-52. 2005
    ..Several well-performed studies have clearly shown that prolonged antimicrobial treatment of "post-Lyme disease" is ineffective. Diagnosis and treatment of Lyme disease continue to improve...
  27. ncbi Neuroimage: disseminated nocardiosis
    P K Sethi
    Clin Neurol Neurosurg 110:98-100. 2008
  28. ncbi Glycoconjugates: roles in neural diseases caused by exogenous pathogens
    Cara Lynne Schengrund
    The Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, 17033, USA
    CNS Neurol Disord Drug Targets 5:381-9. 2006
    ....
  29. ncbi Expression of neurotrophic factors in cerebrospinal fluid and plasma of children with viral and bacterial meningoencephalitis
    A Chiaretti
    Paediatric Intensive Care Unit, Catholic University Medical School, Rome, Italy
    Acta Paediatr 93:1178-84. 2004
    ....
  30. ncbi Glucocorticoids in central nervous system bacterial infection
    P K Coyle
    Department of Neurology, State University of New York at Stony Brook, 11794, USA
    Arch Neurol 56:796-801. 1999
    To evaluate evidence-based data on adjunctive glucocorticoid therapy in central nervous system bacterial infections.
  31. ncbi Spectra of central nervous system melioidosis
    Kalai Arasu Muthusamy
    University Laboratory of Physiology, Oxford University, Parks Road, Oxford OX1 3PT, United Kingdom
    J Clin Neurosci 14:1213-5. 2007
    ..All these patients underwent surgical drainage leading to bacteriological diagnosis as well as appropriate long-term antibiotic therapy. All had good recovery at 6 months after completion of treatment...
  32. ncbi [Endocranial bacterial infections originating in the otorhinolaryngologic area]
    Julijana Dragojlović
    Institute of Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade
    Srp Arh Celok Lek 130:16-21. 2002
    ..Following the treatment in our institution, 20% of patients underwent surgical treatment of chronical otitis or endocranial complications (empyema and abscessus). The mortality rate of patients was 35%...
  33. pmc Pathophysiology of septic encephalopathy--an unsolved puzzle
    Michael A Flierl
    Department of Orthopaedic Surgery, University of Colorado School of Medicine, Denver Health Medical Center, 777 Bannock Street, Denver, CO 80204, USA
    Crit Care 14:165. 2010
    ..A better understanding of the pathophysiological events leading to septic encephalopathy appears crucial to advance the clinical care for this vulnerable patient population...
  34. ncbi Acute central nervous system infections in adults--a retrospective cohort study in the NHS North West region
    B D Michael
    Brain Infections Group, Division of Neurological Science, University of Liverpool, Liverpool, UK
    QJM 103:749-58. 2010
    ..A recent pilot study suggested that management of patients with suspected viral encephalitis was often suboptimal...
  35. ncbi Residual brain infection in relapsing-fever borreliosis
    Diego Cadavid
    Department of Neurology and Neuroscience and Center for the Study of Emerging Pathogens, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark 07103, USA
    J Infect Dis 193:1451-8. 2006
    ..Less understood is the persistence of RF borreliae in the brain after they are cleared from the blood, referred to as residual brain infection (RBI). Our goal was to investigate the phenomenon of RBI in RF...
  36. ncbi Head and neck emergencies: bacterial meningitis, encephalitis, brain abscess, upper airway obstruction, and jugular septic thrombophlebitis
    Catherine J Derber
    Department of Internal Medicine, Division of Infectious Diseases, Eastern Virginia Medical School, Norfolk, VA, USA
    Med Clin North Am 96:1107-26. 2012
    ..Brain infections can have high morbidity among survivors. In this article, the causes, diagnostic tests, treatment, and prognosis are reviewed for some of the more common head and neck infectious disease emergencies...
  37. ncbi Obsessive-compulsive disorder following brain injury: a review
    Bernardus R Coetzer
    North Wales Brain Injury Service, Conwy and Denbighshire NHS Trust, Colwyn Bay Hospital, United Kingdom
    Int J Psychiatry Med 34:363-77. 2004
    ..However, the first onset of obsessions and compulsions following a brain injury has been described, but cognitive impairments can potentially color the presentation...
  38. ncbi Brain abscess from a peritonsillar abscess in an immunocompetent child: a case report and review of the literature
    Senthilkumar Sankararaman
    Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
    Pediatr Neurol 47:451-4. 2012
    ..The cerebral abscess was conservatively treated with intravenous antibiotics. The patient developed hydrocephalus as a sequela to the involvement of the basal meninges...
  39. pmc Brain microbial populations in HIV/AIDS: α-proteobacteria predominate independent of host immune status
    William G Branton
    Department of Medicine Neurology, University of Alberta, Edmonton, Alberta, Canada
    PLoS ONE 8:e54673. 2013
    ..Thus, α-proteobacteria represented the major bacterial component of the primate brain's microbiome regardless of underlying immune status, which could be transferred into naïve hosts leading to microbial persistence in the brain...
  40. ncbi Kaleidoscopic presentation of neurobrucellosis
    Praveen Kesav
    Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
    J Neurol Sci 331:165-7. 2013
    ..Favourable outcomes can be achieved in neurobrucellosis with appropriate protracted polymicrobial antibiotic therapy as was illustrated in our patient...
  41. ncbi First report of probable neurobrucellosis in Australia
    Wendy J Munckhof
    Infection Management Service, Princess Alexandra Hospital, Brisbane, QLD, Australia
    Med J Aust 199:423-5. 2013
    ..Treatment with intravenous ceftriaxone and oral rifampicin, doxycycline and trimethoprim–sulfamethoxazole resulted in a good clinical response...
  42. ncbi Encephalitis
    Karen L Roos
    Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA Electronic address
    Handb Clin Neurol 121:1377-81. 2014
    ..The etiology, clinical presentation, diagnosis, and treatment of viral encephalitis is discussed in this chapter. ..
  43. ncbi Risk factors for infections related to external ventricular drainage
    D Hoefnagel
    Erasmus Medical Centre, Department of Neurosurgery, Rotterdam, The Netherlands
    Acta Neurochir (Wien) 150:209-14; discussion 214. 2008
    ..The major complication of this procedure is an EVD-related infection, i.e., meningitis or ventriculitis. The purpose of the present retrospective single centre study is to assess the possible causes of these infections...
  44. ncbi Molecular mechanisms of axonal damage in inflammatory central nervous system diseases
    Harald Neumann
    Neuroimmunology Unit, European Neuroscience Institute Göttingen, Gottingen, Germany
    Curr Opin Neurol 16:267-73. 2003
    ..Axonal injury has attracted considerable interest during the past few years because the degree of axonal damage appears to determine long-term clinical outcome...
  45. ncbi Cerebral infarct due to meningovascular neurobrucellosis: a case report
    Saime Ay
    Department of Physical Medicine and Rehabilitation, Ufuk University School of Medicine, Ankara, Turkey
    Int J Infect Dis 14:e202-4. 2010
    ..5-25%. The aim of this report is to underline the importance of brucellosis, which is an endemic infection in our country, during the diagnostic evaluation of stroke...
  46. ncbi International and specialty trends in the use of prophylactic antibiotics to prevent infectious complications after insertion of external ventricular drainage devices
    Paul J McCarthy
    Department of Neurosurgery, Louisiana State University Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71130, USA
    Neurocrit Care 12:220-4. 2010
    ..Little evidence exists to support either regime. To determine current practices or to determine if an unintended consensus has developed, a survey was taken concerning antibiotic prophylaxis with EVD insertion...
  47. ncbi Microbiology and antimicrobial treatment of orbital and intracranial complications of sinusitis in children and their management
    Itzhak Brook
    Department of Pediatrics, Georgetown University School of Medicine, 4431 Albemarle Street NW, Washington, DC 20016, USA
    Int J Pediatr Otorhinolaryngol 73:1183-6. 2009
    ..Early recognition and appropriate surgical and medical therapy are essential to ensure recovery...
  48. ncbi [Neurobrucellosis: clinical features and therapeutic responses in 15 patients]
    S Koussa
    Service de Neurologie, Hotel Dieu de France, Université Saint Joseph, Beyrouth, Liban
    Rev Neurol (Paris) 159:1148-55. 2003
    ..The differential diagnosis of neurobrucellosis is wide. However, in endemic areas, the disease should be ruled out in all patients who develop unexplained neurological symptoms...
  49. ncbi Clinical characteristics and outcome of brain abscess: systematic review and meta-analysis
    Matthijs C Brouwer
    From the Departments of Neurology, Center of Infection and Immunity Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
    Neurology 82:806-13. 2014
    ..To define clinical characteristics, causative organisms, and outcome, and evaluate trends in epidemiology and outcome of brain abscesses over the past 60 years...
  50. pmc Invasion of the central nervous system by intracellular bacteria
    Douglas A Drevets
    Department of Medicine, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Clin Microbiol Rev 17:323-47. 2004
    ..Recent experimental data showing that L. monocytogenes can invade the CNS by more than one mechanism make it a useful model for discussing the various routes for neuroinvasion used by intracellular bacterial pathogens...
  51. ncbi The effects of antimicrobial and antiepileptic treatment on the outcome of epilepsy associated with central nervous system (CNS) infections
    Gagandeep Singh
    Department of Neurology, Dayanand Medical College and Hospital, Ludhiana, India
    Epilepsia 49:42-6. 2008
    ..Finally, treatment with antiepileptic drugs (AEDs) needs to be optimally defined in the case of epilepsy associated with neurological infectious disorders...
  52. ncbi [Case report: subdural hemorrhage in neurobrucellosis]
    Günay Tuncer Ertem
    S B Ankara Eğitim ve Araştirma Hastanesi, Infeksiyon Hastaliklari ve Klinik Mikrobiyoloji Klinigi, Ankara
    Mikrobiyol Bul 38:253-6. 2004
    ..The case deserved presentation and discussion since it presented with subdural hemorrhage which is a rare complication of neurobrucellosis...
  53. ncbi Legionnaires' disease with hypoperfusion in the cerebellum and frontal lobe on single photon emission computed tomography
    Noboru Imai
    Department of Neurology, Shizuoka Red Cross Hospital, Shizuoka, Japan
    Intern Med 47:1263-6. 2008
    ..This is the first report demonstrating cerebellar and frontal lobe hypoperfusion without corresponding MRI abnormalities in a patient with central nervous system Legionnaires' disease...
  54. ncbi Do dental infections really cause central nervous system infections?
    Stewart K Lazow
    Department of Dental Oral and Maxillofacial Surgery, Kings County Hospital Center SUNY Brooklyn, 451 Clarkson Avenue, Brooklyn, NY, USA
    Oral Maxillofac Surg Clin North Am 23:569-78, vii. 2011
    ..We seek to answer the question if dental infections really cause CNS infections. In this article, we focus on septic cavernous sinus thrombosis and brain abscess and if it is a diagnosis of exclusion or evidence-based...
  55. ncbi Possible case of CNS Whipple's disease in an adolescent with AIDS
    Sameer J Patel
    Department of Pediatrics, Division of Pediatric Infectious Diseases, Coulumbia University Medical Center, New York, NY 10032, USA
    J Int Assoc Physicians AIDS Care (Chic) 7:69-73. 2008
    ....
  56. ncbi [Brain abscess (80 cases)]
    S Hilmani
    Service de Neurochirurgie, CHU Ibn Rochd, BP 20100, Casablanca, Maroc
    Neurochirurgie 55:40-4. 2009
    ..This is a rare pathology, with a relatively poor prognosis. Therapy continues to be debated and the results are inconsistent. The objectives of this study were to define the factors influencing prognosis...
  57. ncbi Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis
    Lars Ove Brandenburg
    Department of Anatomy and Cell Biology, RWTH Aachen University, Aachen, Germany
    J Neuropathol Exp Neurol 67:1041-54. 2008
    ..Together, these results suggest that cathelicidins produced by glia and other cells play an important part in the innate immune response against pathogens in central nervous system bacterial infections.
  58. ncbi Outbreak of Serratia marcescens bloodstream and central nervous system infections after interventional pain management procedures
    Adam L Cohen
    Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin J Pain 24:374-80. 2008
    ..To determine the cause of an outbreak of Serratia marcescens infections in patients after interventional pain management procedures at an outpatient pain clinic...
  59. ncbi An unusual case of spondylodiscitis
    Luis García-Bordes
    Department of Orthopaedic Surgery and Traumatology, Clínica Copérnico, Barcelona, Spain
    Spine (Phila Pa 1976) 35:E167-71. 2010
    ..A case report of spontaneous pyogenic spondylodiscitis and epidural abscess in vertebral fracture by an uncommon pathogen is described...
  60. ncbi Intracranial infection due to non-typhoidal Salmonella: report of four cases
    R Bellamy
    J Infect 44:207-8. 2002
  61. ncbi Cure of multiresistant Acinetobacter baumannii central nervous system infections with intraventricular or intrathecal colistin: case series and literature review
    John Ng
    Department of Microbiology and Infectious Diseases, South Western Area Pathology Service, Liverpool, Sydney, New South Wales, Australia
    J Antimicrob Chemother 58:1078-81. 2006
    ..Colistin remains one of the few remaining treatment options for MRAB but has poor CNS penetration. We describe our experience with intraventricular or intrathecal colistin for this infection...
  62. ncbi [A draft of novel classification for the consequences of perinatal nervous system lesions in infants under 1 year of age]
    A S Burkova
    Zh Nevrol Psikhiatr Im S S Korsakova 104:74-7. 2004
  63. pmc Listeria monocytogenes-infected phagocytes can initiate central nervous system infection in mice
    D A Drevets
    Department of Medicine, Oklahoma University Health Sciences Center and the Harold Muchmore Laboratories for Infectious Diseases Research of the Veterans Administration Medical Center, Oklahoma City, Oklahoma 73104, USA
    Infect Immun 69:1344-50. 2001
    ..monocytogenes and then reenter the bloodstream and contribute to the systemic dissemination of bacteria...
  64. ncbi Cultivation of Tropheryma whipplei from cerebrospinal fluid
    Matthias Maiwald
    Department of Microbiology, Stanford University School of Medicine, Stanford, California, USA
    J Infect Dis 188:801-8. 2003
    ..This first isolation of T. whipplei from CSF provides clear evidence of viable bacteria in the central nervous system in individuals with WD, even after prolonged antibiotic therapy...
  65. ncbi An unusual case of neurobrucellosis presenting as demyelination disorder
    Omer Bektas
    Division of Pediatric Neurology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey
    Turk J Pediatr 55:210-3. 2013
    ..Additionally, this case is the first in terms of involvement of the corpus callosum in neurobrucellosis. In this article, we present an unusual case of neurobrucellosis. ..
  66. ncbi Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitis
    Anneleen Notebaert
    Department of Pediatric Neurology, Ghent University Hospital, Ghent, Belgium
    Pediatr Neurol 48:135-8. 2013
    ..In the article, previously reported patients with MERS type 2 lesions are reviewed...
  67. ncbi Evaluation of children with neurobrucellosis
    S Akbayram
    Department of Pediatrics, Yuzuncu Yil University, Van, Turkey
    Bratisl Lek Listy 113:424-30. 2012
    ..Brucellosis is an endemic disease in many areas throughout the world. Central nervous system involvement is a serious complication of brucellosis with a ratio of 4-11% of all patients...
  68. ncbi [MR imaging in the diagnosis of primary and secondary cerebral infections]
    K Krope
    Radiologie, Universitat Tubingen
    Rofo 185:539-45. 2013
    ..Both specific MR sequences and imaging characteristics of major cerebral infections are addressed in this overview. Furthermore, limitations and pitfalls of the method are discussed...
  69. ncbi Neurobrucellosis: clinical and diagnostic features
    Tumer Guven
    Infectious Diseases and Clinical Microbiology Clinic, Ataturk Training and Research Hospital, Ankara, Turkey
    Clin Infect Dis 56:1407-12. 2013
    ..We describe the neurological involvement in brucellosis and revisited diagnostic criteria for neurobrucellosis...
  70. ncbi Co-infection of HIV and tropical infectious agents that affect the nervous system
    L Chimelli
    Division of Pathology, National Institute of Cancer, Rua Cordeiro da Graça 156, Santo Cristo, Rio de Janeiro, RJ, CEP 20220 400, Brazil
    Rev Neurol (Paris) 168:270-82. 2012
    ..This article reviews some of the key diagnostic aspects of tropical infections associated with HIV infection...
  71. pmc Neurologic complications of HIV-1 infection and its treatment in the era of antiretroviral therapy
    Sarah M Kranick
    National Institutes of Health, Building 10, 6 5700, Bethesda, MD 20892, USA
    Continuum (Minneap Minn) 18:1319-37. 2012
    ..Additionally, as successful virologic control has extended the life span of patients with HIV infection, neurologists are called upon to manage long-term complications, such as neurocognitive disorders and peripheral neuropathy...
  72. pmc Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study
    Paola Di Carlo
    Department of Sciences for Health Promotion, University of Palermo, via del Vespro 133, Palermo I 90127, Italy
    BMC Pediatr 11:108. 2011
    ....
  73. ncbi Staphylococcus aureus brainstem abscess in a Brazilian Amazon man. Case report
    de Nazareth Hermes
    Department of Neurosurgery, Hospital Ophir Loyola, Belem, Para, Brazil
    J Neurosurg Sci 55:383-5. 2011
    ..This case reinforces the importance of an early suspicion of BSA in patients with unexplained fever and neurologic deficits, especially sixth and seventh cranial nerve lesions, to minimize permanent damage...
  74. ncbi Central nervous system infection with Staphylococcus intermedius secondary to retrobulbar abscessation in a dog
    James A C Oliver
    Davies Veterinary Specialists, Manor Farm Business Park, Higham Gobion, Hertfordshire SG5 3HR, UK
    Vet Ophthalmol 12:333-7. 2009
    ....
  75. ncbi Community-acquired Klebsiella pneumoniae central nervous system infections in adults in Singapore
    A G Habib
    Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, 119074, Singapore, Singapore
    Eur J Clin Microbiol Infect Dis 22:486-8. 2003
    ....
  76. ncbi Emerging therapeutic options in fulminant invasive rhinocerebral mucormycosis
    Kathrin Scheckenbach
    Department of Otorhinolaryngology, Head and Neck Surgery, Heinrich Heine University Dusseldorf, Moorenstrasse 5, Dusseldorf, Germany
    Auris Nasus Larynx 37:322-8. 2010
    ..Due to the lack of typical clinical signs, diagnosis relies on histopathology. Therapy consists of the management of predisposing factors, radical surgical intervention and systemic antifungal therapy...
  77. ncbi Alzheimer's disease and infection: do infectious agents contribute to progression of Alzheimer's disease?
    Kie Honjo
    L C Campbell Cognitive Neurology Research Unit, Heart and Stroke Foundation Centre for Stroke Recovery, Section of Neurology, Department of Medicine, Sunnybrook Health Science Centre and University of Toronto, Toronto, Ontario, Canada
    Alzheimers Dement 5:348-60. 2009
    ..If this hypothesis holds true, early intervention against infection may delay or even prevent the future development of AD...
  78. ncbi Overview of neurobrucellosis: a pooled analysis of 187 cases
    Hanefi Cem Gul
    Department of Infectious Diseases and Clinical Microbiology, Gulhane Medical Academy, Ankara, Turkey
    Int J Infect Dis 13:e339-43. 2009
    ..5% with suitable antibiotics. Neurobrucellosis may mimic various pathologies. For this reason, a thorough evaluation of the patient with probable disease is crucial for an accurate diagnosis and proper management of the disease...
  79. ncbi Pathogenesis of septic encephalopathy
    Peter Pytel
    Department of Pathology, University of Chicago, Chicago, Illinois 60637, USA
    Curr Opin Neurol 22:283-7. 2009
    ..Here, we review recent advances in our understanding of septic encephalopathy, from molecular mechanisms to behavioral alterations, from diagnostic tools to potential therapeutic agents...
  80. ncbi Concomitant presentation of a glioblastoma multiforme with superimposed abscess
    David H Jho
    Neurosurgery Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    World Neurosurg 75:126-31; discussion 50-3. 2011
    ..In the present report we evaluate the diagnosis and treatment of a glioblastoma multiforme with an intratumoral abscess...
  81. ncbi Bug's life
    John McCrone
    Lancet Neurol 2:710. 2003
  82. ncbi A severe headache
    Beau J Bagley
    LSU Health Sciences Center and Children s Hospital, Department of Pediatrics, New Orleans, Louisiana 70118, USA
    Clin Pediatr (Phila) 43:301-2. 2004
  83. ncbi Burden of neuroinfectious diseases on the neurology service in a tertiary care center
    K Tan
    Department of Neurology, 509 Pathology, 600 N Wolfe St, Baltimore, MD, USA
    Neurology 71:1160-6. 2008
    ..We aimed to determine the burden of neurologic infections on the neurology service in a tertiary care center and identify challenges in the diagnosis and treatment of these infections...
  84. pmc NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens
    Vinita S Chauhan
    Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, USA
    Glia 57:414-23. 2009
    ..As such, we have identified NOD2 as an important component in the generation of damaging CNS inflammation following bacterial infection...
  85. ncbi [Bacterial infections of the central nervous system]
    M Klein
    Neurologische Klinik und Poliklinik, Klinikum Grosshadern, Universitat Munchen, Marchioninistrasse 15, Munich
    Nervenarzt 81:150-61. 2010
    ..Here, the relevant diagnostic and therapeutic aspects of three common bacterial infections of the central nervous system (neuroborreliosis, bacterial meningitis, and brain abscess) are discussed...
  86. ncbi Principles of antimicrobial therapy
    JEFFREY M TESSIER
    Virginia Commonwealth University, Richmond, 23298 0049, USA
    Handb Clin Neurol 96:17-29. 2010
    ..g., improved symptoms, lack of new neurological findings) and radiographic changes (e.g., reduction in cavity size)...
  87. ncbi [Cervical epidural abscess as a cause of tetraparesis]
    J Gonzalez-Garcia
    Servicio de Neurocirugia, Hospital General de Galicia, Santiago de Compostela, La Coruna, Espana
    Rev Neurol 29:727-30. 1999
    ..Usually, the patient presents with back pain in the affected spinal segment, but the condition is rarely considered in the differential diagnosis...
  88. ncbi Immune reactions to Listeria monocytogenes in the brain
    D Schluter
    Institut für Med Mikrobiologie und Hygiene, Universitat Heidelberg, Universitatsklinikum Mannheim, Germany
    Immunobiology 201:188-95. 1999
    ..The favorable prognosis of immunized mice correlated with a reduced intracerebral bacterial load, an increased recruitment of protective CD4+ and CD8+ T cells as well as an upregulated mRNA production of protective cytokines...
  89. ncbi Neurobrucellosis--a rare complication of renal transplantation
    B Yousif
    Clinical Medical Services Department, Saudi Aramco-Dhahran Health Center, Saudi Aramco Medical Services Organization, Dhahran, Saudi Arabia
    Am J Nephrol 21:66-8. 2001
    ..Treatment with doxycycline and rifampin led to a clinical cure as well as to marked improvement in the Brucella titer...
  90. pmc Effect of deficiency of tumor necrosis factor alpha or both of its receptors on Streptococcus pneumoniae central nervous system infection and peritonitis
    A Wellmer
    Departments of Neurology, , , Germany
    Infect Immun 69:6881-6. 2001
    ..Early leukocyte influx into the peritoneum was impaired in TNF-alpha-deficient mice. The lack of TNF-alpha or its receptors renders mice more susceptible to S. pneumoniae infections...
  91. ncbi Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells
    You hong Cui
    Laboratory of Molecular Immunoregulation, Division of Basic Sciences, National Cancer Institute, Building 560, Frederick, MD 21702, USA
    J Immunol 168:434-42. 2002
    ..Thus, LPS selectively modulates the function of chemoattractant receptors in microglia and may promote host response in inflammatory diseases in the CNS...
  92. ncbi Intracranial Salmonella infections: meningitis, subdural collections and brain abscess. A series of six surgically managed cases with follow-up results
    Ashok K Mahapatra
    Department of Neurosurgery, The National Neurosurgical Centre, Khoula Hospital, Mina Al Fahal, Muscat, Sultanate of Oman
    Pediatr Neurosurg 36:8-13. 2002
    ..This study suggests that a high index of suspicion, early diagnosis and quick evacuation lead to success; this point is highlighted with the help of a review of the literature...
  93. doi Bartonella-associated meningoradiculoneuritis and dermatitis or panniculitis in 3 dogs
    J R Cross
    Department of Small Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA
    J Vet Intern Med 22:674-8. 2008
  94. ncbi Neurobrucellosis: clinical, diagnostic, therapeutic features and outcome. Unusual clinical presentations in an endemic region
    Nurgul Ceran
    Department of Infectious Diseases, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
    Braz J Infect Dis 15:52-9. 2011
    ..In inhabitants or visitors of endemic areas, neurobrucellosis should be kept in mind in cases that have unusual neurological manifestations...
  95. ncbi Cerebellar abscess due to Listeria monocytogenes
    Bassam M Addas
    Department of Surgery, King Abdulaziz University Hospital, Riyadh, Kingdom of Saudi Arabia
    Saudi Med J 23:226-8. 2002
    ..The diagnosis of listeria monocytogenes was made in the surgical specimen. Our case illustrates the difficulty of early diagnosis of cerebellar listeria monocytogenes abscesses and the importance of prompt neurosurgical intervention...
  96. ncbi Antibiotics-impregnated ventricular catheter versus systemic antibiotics for prevention of nosocomial CSF and non-CSF infections: a prospective randomised clinical trial
    George K C Wong
    Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
    J Neurol Neurosurg Psychiatry 81:1064-7. 2010
    ..This study aims to compare antibiotic impregnated catheters with conventional catheters coupled with systemic antibiotics...
  97. ncbi Massive ascites as unique sign of shunt infection by Propionibacterium acnes
    Nicola Montano
    Institute of Neurosurgery, Catholic University, Rome
    Br J Neurosurg 24:221-3. 2010
    ..We report on a case of P. acnes shunt infection presenting with massive ascites as the unique sign of CSF infection. Shunt removal, antibiotic therapy and drenaige of ascites were performed with a rapid clinical recovery...
  98. ncbi Chlamydia pneumoniae and multiple sclerosis: the latest etiologic candidate
    Khurram Bashir
    Department of Neurology, University of Alabama at Birmingham, 220A Ryals Building, 1665 University Blvd, Birmingham, AL 35294 0022, USA
    Epidemiology 14:133-4. 2003
  99. ncbi Secondary intracranial causes for headaches in children
    Rooman Ahad
    Department of Neurology, Division of Pediatric Neurology, Johns Hopkins Hospital, 200 N Wolfe Street, Baltimore, MD 21287, USA
    Curr Pain Headache Rep 12:373-8. 2008
    ..This article discusses these secondary causes of headaches due to primary brain etiologies, focusing on aspects of the history that should lead a neurologist to order neuroimaging or electroencephalographic studies for these children...
  100. ncbi Whipple disease confined to the central nervous system presenting as a solitary frontal tumor. Case report
    Mario Löhr
    Department of Neurosurgery, University of Cologne, Germany
    J Neurosurg 101:336-9. 2004
    ..A review of diagnostic and therapeutic options in suspected cases is presented...
  101. ncbi The association between central nervous system (CNS) infections and epilepsy: epidemiological approaches and microbiological and epileptological perspectives
    Gagandeep Singh
    Department of Neurology, Dayanand Medical College and Hospital, Ludhiana, India gagandeep
    Epilepsia 49:2-7. 2008
    ....

Research Grants10

  1. Ethanol, Tat and the Blood-brain barrier
    Kwang Kim; Fiscal Year: 2004
    ..e., nitric oxide and signaling pathways. The information derived from this proposal should enhance our understanding of the role of ethanol in HIV-1 neuropthogenesis. ..
  2. Monocyte Biology and Biodefense
    DOUGLAS DREVETS; Fiscal Year: 2005
    ..These data will then catalyze development of rational therapies to improve host defenses against severe and overwhelming infection by category A and B intracellular bacterial pathogens. ..
  3. HIV-1 protein neurotoxicity and ethanol pre-conditioning
    Michael Collins; Fiscal Year: 2006
    ..abstract_text> ..
  4. Cryptococcus traversal of Brain Endothelial cells
    Kwang Kim; Fiscal Year: 2007
    ..neoformans traversal of HBMEC monolayers and will be the basis of future investigations to characterize microbial-host interactions that are relevant to the pathogenesis of cryptococcal meningitis/meningoencephalitis. ..
  5. Genome-wide screening of E. coli for bacteremia
    Kwang Kim; Fiscal Year: 2007
    ..coli bacteremia should help in development of preventive measures such as vaccines against E. coli bacteremia. [unreadable] [unreadable] [unreadable]..
  6. GP 120 MEDIATED ACTIVATION OF BRAIN ENDOTHELIAL CELLS
    Kwang Kim; Fiscal Year: 2002
    ..e., roles of G proteins and signaling pathways, platelet-activating factor (PAF). The information derived from this proposal should enhance our understanding of the role of HBMEC in HIV encephalopathy. ..
  7. Borrelia lipoproteins with the cerebral microcirculation
    Diego Cadavid; Fiscal Year: 2007
    ..2. Investigate whether Vspl enters BMEC. 3. Determine whether Vspl crosses BMEC barriers. 4. Identify the structural features that mediate the interaction of Vspl with BMEC. [unreadable] [unreadable]..
  8. D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder
    Eric Storch; Fiscal Year: 2007
    ..Such agents may have utility in improving outcome, reducing premature therapy termination, and targeting patients who have been treatment refractory. [unreadable] [unreadable] [unreadable]..
  9. E. COLI BINDING TO BRAIN ENDOTHELIAL CELLS
    Kwang Kim; Fiscal Year: 2003
    ....
  10. E. coli invasion of brain endothelial cells
    Kwang Kim; Fiscal Year: 2008
    ..3.To determine the role of K1 capsule in E. coli trafficking in HBMEC. Further understanding and characterization of E. coli K1-HBMEC interactions should allow us to develop novel strategies to prevent this serious infection. ..