bacterial eye infections

..To report a case of Gemella hemolysans keratitis with consecutive endophthalmitis...

..The causative organisms of future incidents of postoperative endophthalmitis will determine whether the present protocol must be reappraised...

..The available literature regarding the individual cases is summarized and a brief discussion of post-traumatic endophthalmitis is presented, with reference to a recently published large series at the authors' institution...

..24%). Use of topical povidone-iodine in over 3000 cases was not associated with any adverse reactions. In a majority of the observed cases of endophthalmitis, some form of intraoperative communication with the vitreous cavity existed...

..Syphilitic uveitis in HIV-infected patients seems to have a more severe course and may relapse despite high-dose intravenous penicillin therapy...

..To assess the impact of primary injection of intravitreal antibiotics and delayed pars plana vitrectomy with removal of intraocular foreign body (IOFB) in patients with clinical features of bacterial endophthalmitis and retained IOFB...

..To determine the efficacy of intraoperative antibiotic use in irrigating solutions on aqueous humor contamination during phacoemulsification surgery and to evaluate the corresponding risk of postoperative endophthalmitis...

..To assess the incidence of anterior chamber bacterial contamination during cataract surgery, and compare results of injector implantation and forceps implantation of foldable intraocular lenses (IOLs)...

..To report results in the European Society of Cataract & Refractive Surgeons (ESCRS) multicenter study of the prophylaxis of endophthalmitis after cataract surgery...

..To evaluate the efficacy of prophylactic intracameral cefazolin in preventing endophthalmitis in cataract surgery...

..To report a patient with Neisseria meningitidis endophthalmitis without associated meningitis with full visual recovery, with early detection of the microorganism using polymerase chain reaction (PCR) analysis...

..To report a novel case of infectious crystalline keratopathy after penetrating keratoplasty caused by Gemella haemolysans...

..CONCLUSIONS: G. haemolysans can be a causative organism of infectious crystalline keratopathy. This infection can arise in a postkeratoplasty patient despite prophylaxis with a fourth-generation fluoroquinolone...

..CONCLUSIONS: In this retrospective, case-controlled study, clear corneal incisions were found to be a statistically significant risk factor for acute post-cataract surgery endophthalmitis when compared with scleral tunnel incisions...

..We also describe an interaction between this organism and a co-infective organism that may account for the unusual clinical course...

..To investigate the efficacy of intravitreal piperacillin/tazobactam (250 microg/0.1 ml) in the treatment of experimental Pseudomonas aeruginosa endophthalmitis in rabbits...

..To study the ocular manifestations during the acute phase of leptospirosis and their incidence in hospitalized patients due to systemic complications, and to verify the importance of routine ophthalmologic care in these cases...

..To investigate the role of pathogenic leptospires as an aetiological agent of ocular diseases, we report the results of a 5-year survey in New Caledonia...

..To describe postoperative endophthalmitis caused by sequestered Acinetobacter calcoaceticus...

..7 +/- 1.3; CI 1.06 to 7.14 P=.037). CONCLUSION: In sutureless cataract surgery, surgical complications and wound leak on the first postoperative day were most strongly associated with endophthalmitis...

..To identify the prognostic factors that predict final visual outcome in eyes with posterior segment intraocular foreign body (IOFB) injuries managed by primary pars plana vitrectomy...

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..The patient was successfully treated with vancomycin. Polymerase chain reaction and subsequent DNA-typing were useful in detecting the microorganisms that caused the chronic endophthalmitis...

..Infections are caused by gram-positive organisms sensitive to bacitracin and the combination of trimethoprim-sulfamethoxazole but often resistant to aminoglycosides and/or fluoroquinolones...

..A 3-day application of topical ofloxacin before surgery did not reduce the anterior chamber aqueous contamination rate relative to a 1-hour application...

..Intraoperative posterior capsule rupture is associated with an 8- to 11-fold higher risk of acute endophthalmitis, suggesting that these eyes should be closely monitored for signs of infection in the immediate postoperative period...

..CONCLUSIONS: With regard to bacterial endophthalmitis prophylaxis in cataract surgery, current literature most strongly supports the use of preoperative povidone-iodine antisepsis...

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..CONCLUSIONS: Endophthalmitis caused by P. aeruginosa is associated with poor visual outcomes despite prompt treatment with intravitreal antibiotics to which the organisms were sensitive...

..To characterize and analyze the posterior segment manifestations of Mediterranean spotted fever (MSF), an infectious disease caused by Rickettsia conorii...

..CONCLUSIONS: The clinical appearance of posterior placoid chorioretinitis in syphilis may be modulated by the immune status of the patient...

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..To investigate whether intravitreal injection of dexamethasone in addition to antibiotics can minimize intraocular tissue injury caused by Staphylococcus aureus endophthalmitis...

..Bacterial keratitis may occur after nonpenetrating glaucoma surgery and should be included in the list of early postoperative complications...

..Our findings justify a larger multicenter randomized study...

..Parents of children who consider overnight orthokeratology should evaluate the benefit of temporary myopia reduction and the risk of infection...

..To report four cases of ocular infection caused by Gemella species...

..The authors analyzed the effectiveness of early treatment with vancomycin or gatifloxacin, with or without dexamethasone, for experimental B. cereus endophthalmitis...

..To evaluate the causative organisms of and predisposing medical conditions in endogenous endophthalmitis and review visual acuity after pars plana vitrectomy...

..CONCLUSIONS: Acute-onset endophthalmitis may occur in a cluster of patients within a short time frame. Early diagnosis and treatment may result in favorable visual outcomes...

..To report the incidence of acute endophthalmitis as a complication of intravitreal bevacizumab (Avastin) (IVB) injection in a tertiary vitreoretinal group practice...

..Bacillus cereus causes the most virulent and refractory form of endophthalmitis. The authors analyzed effectiveness of intravitreal vancomycin with or without dexamethasone for experimental Bacillus cereus endophthalmitis...

..To investigate the rate of bleb-related endophthalmitis over 5 years in a Chinese population. METHODS.:Retrospective chart review...

..To report the clinical features, causative organisms, and visual acuity outcomes associated with endophthalmitis after clear corneal cataract surgery and to compare outcomes with those of the Endophthalmitis Vitrectomy Study (EVS)...

..To report the use of pulsed-field gel electrophoresis (PFGE) in the investigation of the origin of infectious keratitis...

..To describe a case of a perforated corneal ulcer leading to a bacterial endophthalmitis in a patient with graft-versus-host disease (GVHD)...

..To determine the risk factors for post-traumatic endophthalmitis in patients with positive intraocular culture...

..To report an unusual case of community-acquired Pseudomonas aeruginosa pneumonia in an immunocompetent host complicated by orbital cellulitis, panophthalmitis, and subcutaneous nodules...

..To describe the clinical manifestations and outcomes in 4 patients with endophthalmitis caused by Bacillus cereus and Chlamydia trachomatis...

..To compare the clinical features and antibiotic susceptibility of ocular methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA)...

..A repeat anterior chamber tap was negative. P. luteola may be a relatively nonvirulent cause of chronic endophthalmitis. Good visual outcomes may be obtained with appropriate therapy...

..Resolution of systemic infection occurred with the addition of granulocyte macrophage-colony stimulating factor. This is the first reported case of M. haemophilum endophthalmitis...

..To report a rare presentation of bilateral, sequential Pseudomonas aeruginosa endogenous endophthalmitis in a woman with bronchiectasis...

..parainfluenzae, aphrophilus, paraphrophilus), Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corodens, and Kingella kingae] group bacterial endophthalmitis can yield good results...

..These results suggest that successful management might be improved by addressing factors contributing to disease progression during sterilization of the cornea by antibiotics...

..These lenses should be prescribed and used with great care to minimize contact lens-related infectious keratitis...

..To determine the role of pars plana vitrectomy (PPV) in the treatment of Klebsiella pneumoniae endogenous endophthalmitis...

..Chronic urinary tract infection may be a risk factor for postoperative endophthalmitis. A dipstick urinalysis before elective cataract surgery in elderly patients with a history of recurrent urinary tract infections may be considered...

..His contrast sensitivity (Vector Vision CSV 1000 test) performance was also worse than his fellow eye. CONCLUSION: Nocturnal orthokeratology lens wear may be associated with an increased risk of infection...

..To report two cases of Pseudomonas aeruginosa corneal ulcers as a complication of overnight orthokeratology lens wear...

..Good visual outcome was associated with visual acuity of 20/200 or better at diagnosis and with the absence of hypopyon...

..However, modifications of the peptides, the drug delivery systems, or both, will be necessary for effective clinical application...

..aureus-infected eyes, despite the presence of anti-lysostaphin antibody. No adverse reactions were produced by administration of lysostaphin to immunized rabbits...

..CONCLUSION: C. canimorsus keratitis may follow penetrating corneal injury and wound contamination with cat saliva and may be recalcitrant to topical antibiotic therapy...

..CONCLUSIONS: Although infectious keratitis after LASIK is an infrequently reported event, it should be discussed preoperatively with patients as a possible complication...

..0001). Therapy with the mupirocin:polymyxin B combination was equivalent to ciprofloxacin therapy (p = 0.80). CONCLUSION: The mupirocin:polymyxin B combination was effective in treating experimental, and keratitis...

..To report successful management of orthodontic-associated traumatic endophthalmitis...

..The need for prompt vitrectomy as the only chance of retaining at least basic visual functions is fully demonstrated...

..CONCLUSION: Actinomyces species can rarely cause postoperative endophthalmitis, and it should be considered in cases of severe postoperative intraocular inflammation...

..In these eyes, the hypopyon and symptoms quickly resolve without treatment...

..To present and discuss four cases of bilateral endogenous endophthalmitis...

..CONCLUSION: The incidence of endophthalmitis after pars plana vitrectomy is low but the visual acuity outcomes after treatment are generally poor...

..Although bacterial keratitis occurs rarely after refractive surgery, patients should be informed of the potential risk for visual loss caused by this infection...

..After 3 rounds of intravitreal antibiotics injection, the vitreous opacity disappeared on ultrasonographic finding but corneal opacity and corneal neovascularization still remained...

..The emergence of ciprofloxacin-resistant Pseudomonas aeruginosa (CRPA) has created a new therapeutic challenge in ophthalmology. We evaluated ophthalmic antibiotics in vitro and in a rabbit keratitis model to determine effective therapy...

..We describe a case of Staphylococcus epidermidis endophthalmitis in an adult following strabismus surgery treated successfully with intravitreal antibiotics and corticosteroids...

..This case illustrates that microbial pathogens brought underneath the flap by LASIK can persist months later despite antimicrobial treatment...

..One month after penetrating keratoplasty, a male patient suffered recurrent abscess and endophthalmitis caused by mixed bacteria (Staphylococcus aureus and Candida Albicans)...

..When using initial bacteria inocula of 10(8) CFU/mL, an initial burst release provided by soaking the liposomal lenses was required for the first hours to inhibit bacteria growth...

..There is no immediate need for new ophthalmic antibiotics, but increasing resistance is being seen with the widely used fluoroquinolone antibiotics...

..To identify the etiology, incidence and prevalence of ocular bacterial infections, and to assess the in vitro susceptibility of these ocular bacterial isolates to commonly used antibiotics...

..In recent years, a number of papers have been published suggesting its efficacy in animal and human bacterial infections, but none of them addressed the phage potential in ophthalmology, which is the subject of this mini review...

..To report two cases of infectious keratitis that developed 2 and 6 years after LASIK...

..However, in the long-term treatment of chronic blepharitis the well-known toxic problems of neomycin sulphate have to be taken into account...

..CONCLUSIONS: Ocular manifestations of cat scratch disease can include diffuse thickening of the choroid. Cat scratch disease may manifest with angiographic features suggestive of Vogt-Koyanagi-Harada disease...

..Two months after surgery, both transplants remained clear...

..3. Determine the skirt design for optimal stromal tissue integration by evaluating in vitro and in vivo stromal wound healing within photolithographically patterned, microperforated hydrogel arrays. ..

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..To achieve these aims, molecular microbiological, immunological and biochemical methods will be used. ..

..It is expected that the findings will reveal potential targets for early intervention and/or treatment of P. aeruginosa keratitis. ..

..abstract_text> ..

..aeruginosa keratitis and should lead to better characterization of molecules which are potential targets for more effective treatment of corneal inflammation. ..

..Ultimately, the findings from this proposal will be useful clinically in development of better treatments to reduce bacterial keratitis and prevent blindness. ..

..The use of the eye allows one to study a specific restricted organ system, thereby simplifying experimental design and data interpretation...

..The studies proposed will be of value in the development of immunotherapeutics and/or receptor analogs which either alone, or in concert, will serve to prevent or lessen bacterial infectivity and subsequent corneal inflammatory disease...

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..By identifying the bacterial and host factors important in disease, we can exploit these targets for the development of new treatment strategies that will increase the likelihood of preventing blindness following endophthalmitis. ..

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..Identification and characterization of important virulence factors will provide the basis on which information-based therapeutic agents are developed in order to prevent vision loss during B. cereus endophthalmitis. ..

..3. Determine the skirt design for optimal stromal tissue integration by evaluating in vitro and in vivo stromal wound healing within photolithographically patterned, microperforated hydrogel arrays. ..

..3. Determine the skirt design for optimal stromal tissue integration by evaluating in vitro and in vivo stromal wound healing within photolithographically patterned, microperforated hydrogel arrays. ..

..abstract_text> ..

..3. Determine the skirt design for optimal stromal tissue integration by evaluating in vitro and in vivo stromal wound healing within photolithographically patterned, microperforated hydrogel arrays. ..

..Aim 4: To similarly examine specific TIMPs (TIMP-1 and -4) in the pathogenesis of corneal alkali-burn in inbred mice using moderate vs severe burns. ..

..It is expected that our findings will be significant to the clinical care of patients with P. aeruginosa keratitis by providing potential targets for early therapeutic intervention. ..

..These experiments are designed to provide both new knowledge and reagents to help arrest the pathology of S. aureus keratitis. ..

..The quality of the institution, the talents of the specific faculty, the abilities of the applicant pool, and the proven success of the program areadditional strengths of this application. ..

..g. NEI-VFQ 25) and eye service use. Subjects who refuse will be questioned as to reason(s) for refusal. ..

..We believe that these aims are novel, innovative, especially suited to the skills and achievements demonstrated by our laboratory, and highly relevant to clarifying the pathogenesis of anterior uveitis. ..

..These studies should result in a fundamental improvement in the understanding of how T cells behave within a site of inflammation. ..

..The development of alternative and novel therapies for bacterial eye infections will help to prevent scarring and loss of the eye.

..These studies offer a unique opportunity to develop modalities to image the immune response in vivo. ..

..The development of alternative and novel therapies for bacterial eye infections will help to prevent scarring and loss of the eye.