rodent diseases

Summary

Summary: Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs).

Top Publications

  1. ncbi Fleas (siphonaptera) collected from small mammals in Southern Viet Nam in 1997-1998
    G H Adler
    Department of Biology and Microbiology, University of Wisconsin, Oshkosh, 54901, USA
    J Med Entomol 38:210-3. 2001
  2. ncbi Temporal variation of Ixodes ricinus intensity on the rodent host Apodemus flavicollis in relation to local climate and host dynamics
    Roberto Rosa
    Centre for Alpine Ecology, Viote del Monte Bondone, Trento, Italy
    Vector Borne Zoonotic Dis 7:285-95. 2007
  3. ncbi Catarina virus, an arenaviral species principally associated with Neotoma micropus (southern plains woodrat) in Texas
    Maria N B Cajimat
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    Am J Trop Med Hyg 77:732-6. 2007
  4. ncbi Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks
    Makoto Kawahara
    Nagoya City Public Health Research Institute, Hagiyama cho, Mizuho ku, Nagoya, 467 8615, Japan
    Int J Syst Evol Microbiol 54:1837-43. 2004
  5. ncbi Tula virus infections in the Eurasian water vole in Central Europe
    Mathias Schlegel
    Friedrich Loeffler Institut, Institute for Novel and Emerging Infectious Diseases, Greifswald Insel Riems, Germany
    Vector Borne Zoonotic Dis 12:503-13. 2012
  6. doi Rickettsia spp. in wild small mammals in Lower Bavaria, South-Eastern Germany
    Susanne Schex
    Bundeswehr Institute of Microbiology, Munich, Germany
    Vector Borne Zoonotic Dis 11:493-502. 2011
  7. pmc Both nonstructural proteins NS1 and NS2 of pneumonia virus of mice are inhibitors of the interferon type I and type III responses in vivo
    Britta Heinze
    Institute of Virology and Immunobiology, Julius Maximilian University, Versbacher Strasse 7, D 97078 Wurzburg, Germany
    J Virol 85:4071-84. 2011
  8. ncbi Effects of deer density on tick infestation of rodents and the hazard of tick-borne encephalitis. I: empirical assessment
    F Cagnacci
    Department of Biodiversity and Molecular Ecology, Research and Innovation Centre, Fondazione Edmund Mach, Via E Mach 1, I 38010 San Michele all Adige, Trento, Italy
    Int J Parasitol 42:365-72. 2012
  9. ncbi Microclimate and the zoonotic cycle of tick-borne encephalitis virus in Switzerland
    C Burri
    Institute of Biology, Laboratory of Eco Epidemiology of Parasites, University of Neuchatel, Emile Argand 11, 2000 Neuch and tel, Switzerland
    J Med Entomol 48:615-27. 2011
  10. pmc Babesia spp. and Anaplasma phagocytophilum in questing ticks, ticks parasitizing rodents and the parasitized rodents--analyzing the host-pathogen-vector interface in a metropolitan area
    Cornelia Silaghi
    Comparative Tropical Medicine and Parasitology, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Parasit Vectors 5:191. 2012

Research Grants

  1. SCREENING MICE FOR AUDITORY & NEUROBEHAVIORAL PHENOTYPES
    JAMES WILLOTT; Fiscal Year: 2002
  2. Cognitive Function in SLE (COGNITION)
    ROBIN BREY; Fiscal Year: 2007
  3. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2007
  4. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2007
  5. Psychosocial modulation of mammary carcinogenesis
    Jason Yee; Fiscal Year: 2007
  6. CRYSTAL STRUCTURE OF A YERSINIA TYROSINE PHOSPHATASE
    MARK SAPER; Fiscal Year: 1993
  7. Fixed Equipment for DDB Animal Resource
    MARVIN SWINDLE; Fiscal Year: 2009
  8. 5 NUCLEASE ASSAYS FOR RODENT HEALTH MONITORING
    David Besselsen; Fiscal Year: 2001
  9. 5 NUCLEASE ASSAYS FOR RODENT HEALTH MONITORING
    David Besselsen; Fiscal Year: 2000
  10. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2006

Detail Information

Publications247 found, 100 shown here

  1. ncbi Fleas (siphonaptera) collected from small mammals in Southern Viet Nam in 1997-1998
    G H Adler
    Department of Biology and Microbiology, University of Wisconsin, Oshkosh, 54901, USA
    J Med Entomol 38:210-3. 2001
    ....
  2. ncbi Temporal variation of Ixodes ricinus intensity on the rodent host Apodemus flavicollis in relation to local climate and host dynamics
    Roberto Rosa
    Centre for Alpine Ecology, Viote del Monte Bondone, Trento, Italy
    Vector Borne Zoonotic Dis 7:285-95. 2007
    ..This provides important information in terms of monitoring the risk to humans of acquiring pathogen-infected ticks...
  3. ncbi Catarina virus, an arenaviral species principally associated with Neotoma micropus (southern plains woodrat) in Texas
    Maria N B Cajimat
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    Am J Trop Med Hyg 77:732-6. 2007
    ....
  4. ncbi Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks
    Makoto Kawahara
    Nagoya City Public Health Research Institute, Hagiyama cho, Mizuho ku, Nagoya, 467 8615, Japan
    Int J Syst Evol Microbiol 54:1837-43. 2004
    ..It is proposed that this new cluster of bacteria should be designated 'Candidatus Neoehrlichia mikurensis'...
  5. ncbi Tula virus infections in the Eurasian water vole in Central Europe
    Mathias Schlegel
    Friedrich Loeffler Institut, Institute for Novel and Emerging Infectious Diseases, Greifswald Insel Riems, Germany
    Vector Borne Zoonotic Dis 12:503-13. 2012
    ..amphibius. Future longitudinal studies of sympatric Microtus and Arvicola populations and experimental infection studies have to prove the potential of A. amphibius as an additional TULV reservoir host...
  6. doi Rickettsia spp. in wild small mammals in Lower Bavaria, South-Eastern Germany
    Susanne Schex
    Bundeswehr Institute of Microbiology, Munich, Germany
    Vector Borne Zoonotic Dis 11:493-502. 2011
    ..However, with the course of infection and its transmission in wild animals still unknown, further investigations are needed to better understand the natural cycle of SFG rickettsiae...
  7. pmc Both nonstructural proteins NS1 and NS2 of pneumonia virus of mice are inhibitors of the interferon type I and type III responses in vivo
    Britta Heinze
    Institute of Virology and Immunobiology, Julius Maximilian University, Versbacher Strasse 7, D 97078 Wurzburg, Germany
    J Virol 85:4071-84. 2011
    ..The fact that virulence of rPVM lacking NS2 was not recovered completely when both interferon receptors were deleted suggests that NS2 may have further functions outside the IFN system...
  8. ncbi Effects of deer density on tick infestation of rodents and the hazard of tick-borne encephalitis. I: empirical assessment
    F Cagnacci
    Department of Biodiversity and Molecular Ecology, Research and Innovation Centre, Fondazione Edmund Mach, Via E Mach 1, I 38010 San Michele all Adige, Trento, Italy
    Int J Parasitol 42:365-72. 2012
    ....
  9. ncbi Microclimate and the zoonotic cycle of tick-borne encephalitis virus in Switzerland
    C Burri
    Institute of Biology, Laboratory of Eco Epidemiology of Parasites, University of Neuchatel, Emile Argand 11, 2000 Neuch and tel, Switzerland
    J Med Entomol 48:615-27. 2011
    ..The proportion of hosts with cofeeding ticks seemed to be one of the factors that distinguished a TBEV focus from a non-TBEV focus. The enzootic cycle of TBEV might be disrupted when dry and hot springs occur during consecutive years...
  10. pmc Babesia spp. and Anaplasma phagocytophilum in questing ticks, ticks parasitizing rodents and the parasitized rodents--analyzing the host-pathogen-vector interface in a metropolitan area
    Cornelia Silaghi
    Comparative Tropical Medicine and Parasitology, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Parasit Vectors 5:191. 2012
    ..and Anaplasma phagocytophilum in restored areas in both questing and host-attached Ixodes ricinus and Dermacentor reticulatus and their small mammalian hosts...
  11. pmc Hantavirus in African wood mouse, Guinea
    Boris Klempa
    Institute of Virology, Charite Medical School, Campus Charite Mitte, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Emerg Infect Dis 12:838-40. 2006
    ..Sequence and phylogenetic analyses of the genetic material demonstrate a novel hantavirus species, which we propose to name "Sangassou virus."..
  12. doi Murine endogenous retroviruses
    C Stocking
    Heinrich Pette Institute, Hamburg, Germany
    Cell Mol Life Sci 65:3383-98. 2008
    ..We review mechanisms by which an adaptive coexistence has evolved. (Part of a multi-author review)...
  13. pmc New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum
    Feng Liu
    Chinese National Human Genome Center, Shanghai, China
    PLoS Pathog 2:e29. 2006
    ....
  14. ncbi Demographic factors associated with prevalence of antibody to Sin Nombre virus in deer mice in the western United States
    Charles H Calisher
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Foothills Campus, Colorado State University, Fort Collins, Colorado 80523, USA
    J Wildl Dis 43:1-11. 2007
    ..Many of these patterns, which will be useful in the development of predictive models of disease risk to humans, were only detected through the application of data collected over a long (10-yr) period and with abundant replication...
  15. pmc Parasitic loads in tissues of mice infected with Trypanosoma cruzi and treated with AmBisome
    Sabrina Cencig
    Laboratoire de Parasitologie, Faculte de Medecine, Universite Libre de Bruxelles, Brussels, Belgium
    PLoS Negl Trop Dis 5:e1216. 2011
    ..AmBisome (liposomal amphotericin B), already shown efficient after administration for some days in human and experimental infection with Leishmania, has been scarcely studied in T. cruzi infection...
  16. pmc Genotype diversity and distribution of Orientia tsutsugamushi causing scrub typhus in Thailand
    Toon Ruang-areerate
    Research Division, Armed Forces Research Institute of Medical Science, Bangkok 10400, Thailand
    J Clin Microbiol 49:2584-9. 2011
    ..Thus, these new genotypes should be considered for future scrub typhus assay and vaccine development...
  17. ncbi Effect of deer density on tick infestation of rodents and the hazard of tick-borne encephalitis. II: population and infection models
    L Bolzoni
    Department of Biodiversity and Molecular Ecology, Research and Innovation Centre Fondazione Edmund Mach, San Michele all Adige, Trento, Italy
    Int J Parasitol 42:373-81. 2012
    ..As a consequence, using simply the number of ticks per rodent as a predictor of TBE transmission potential could be misleading if competent hosts share habitats with incompetent hosts...
  18. pmc Factors affecting patterns of tick parasitism on forest rodents in tick-borne encephalitis risk areas, Germany
    Christian Kiffner
    Department of Forest Zoology and Forest Conservation incl Wildlife Biology and Game Management, Büsgen Institute, Georg August University Gottingen, Büsgenweg 3, 37077, Gottingen, Germany
    Parasitol Res 108:323-35. 2011
    ..mainly fed on M. glareolus and were seldom found on A. flavicollis. Whereas Ixodes spp. is the dominant tick genus in woodlands of our study area, the distribution and epidemiological role of Dermacentor spp. should be monitored closely...
  19. pmc Leishmania species: detection and identification by nested PCR assay from skin samples of rodent reservoirs
    Amir Ahmad Akhavan
    Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Exp Parasitol 126:552-6. 2010
    ..major and L. turanica, 1.1% by L. major and L. gerbilli, and 2.1% by the three species. We concluded that this method is simple and reliable for detecting and identifying Leishmania species circulating in rodent populations...
  20. pmc Diversity among Tacaribe serocomplex viruses (family Arenaviridae) naturally associated with the Mexican woodrat (Neotoma mexicana)
    Maria N B Cajimat
    Microbiology and Immunology Graduate Program, Graduate School of Biomedical Sciences, University of Texas Medical Branch, Galveston, TX 77555 1019, USA
    Virus Res 133:211-7. 2008
    ..Conceptually, the viruses from Colorado, New Mexico, and Utah and strain AV 9310135 could be grouped together in a species complex in the family Arenaviridae, genus Arenavirus...
  21. ncbi Abundance of wild rodents, ticks and environmental risk of Lyme borreliosis: a longitudinal study in an area of Mazury Lakes district of Poland
    Edward Sinski
    Department of Parasitology, Institute of Zoology, University of Warsaw, Miecznikowa 1, 02 096 Warsaw, Poland
    Ann Agric Environ Med 13:295-300. 2006
    ..It follows, therefore, that any factor which reduces the relative density of A. flavicollis in comparison to other hosts in the wild rodent community, will reduce also the risk of human exposure to Lyme borreliosis spirochetes...
  22. ncbi Prevalence of Leptospira spp. in urban rodents from a groceries trade center of Medellin, Colombia
    Piedad Agudelo-Florez
    Instituto Colombiano de Medicina Tropical Universidad CES, Colombia
    Am J Trop Med Hyg 81:906-10. 2009
    ..interrogans by sequencing. These data show the role of this natural carrier and shedder of pathogenic leptospires in the epidemiology of urban leptospirosis in Colombia...
  23. ncbi Histological study of Trichosomoides nasalis (Nematoda: Trichinelloidea) in the nasal cavities of the murid Arvicanthis niloticus, with associated pathology
    M Diagne
    Departement de Biologie Animale, Faculte des Sciences, Universite Cheikh Anta Diop, Dakar, Senegal
    Parasite 11:351-8. 2004
    ..which live in this part of the mucosa. In rodents, the lesions resulted in rhinosinusitis characterised by a lymphocytic infiltration leading to nasal obstruction...
  24. ncbi Transmission of Black Creek Canal virus between cotton rats
    K L Hutchinson
    Special Pathogens Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Med Virol 60:70-6. 2000
    ..J. Med. Virol. 60:70-76, 2000. Published 2000 Wiley-Liss, Inc...
  25. ncbi Factors affecting the component community structure of haemoparasites in bank voles (Clethrionomys glareolus) from the Mazury Lake District region of Poland
    A Bajer
    Department of Parasitology, Institute of Zoology, University of Warszawa, Poland
    Parasitology 122:43-54. 2001
    ....
  26. doi Molecular survey of Babesia microti in wild rodents in central Croatia
    Relja Beck
    Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Zagreb, Croatia
    Vector Borne Zoonotic Dis 11:81-3. 2011
    ..The results of this study indicate the presence of zoonotic B. microti in A. flavicollis and M. glareolus in Croatia and a potential risk for human health...
  27. doi Male hosts are responsible for the transmission of a trophically transmitted parasite, Pterygodermatites peromysci, to the intermediate host in the absence of sex-biased infection
    Lien T Luong
    Center for Infectious Disease Dynamics, Department of Biology, 208 Mueller Laboratory, The Pennsylvania State University, University Park, PA 16802, USA
    Int J Parasitol 39:1263-8. 2009
    ..We also investigated whether variation in nematode length between male and female hosts could account for this male-biased infectivity, but found no evidence to support that hypothesis...
  28. pmc Serologic and molecular studies of Leptospira and leptospirosis among rats in the Philippines
    Sharon Y A M Villanueva
    Department of Bacteriology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Am J Trop Med Hyg 82:889-98. 2010
    ..Results showed that these four Leptospira serovars and serogroups are circulating among rats, and that these animals may be one of the possible transmission sources of leptospirosis in the Philippines...
  29. doi Study on the movement of Rattus rattus and evaluation of the plague dispersion in Madagascar
    Soanandrasana Rahelinirina
    Institut Pasteur de Madagascar, WHO Collaborating Centre for Plague, Antananarivo, Madagascar
    Vector Borne Zoonotic Dis 10:77-84. 2010
    ..The three study habitats were the risk areas for plague transmission, but the risk appeared highest in the houses and sisals. Rats' movements according to the season were likely directed by the availability of food...
  30. ncbi A longitudinal study of Junin virus activity in the rodent reservoir of Argentine hemorrhagic fever
    J N Mills
    Department of Immunology and Infectious Diseases, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland
    Am J Trop Med Hyg 47:749-63. 1992
    ..These distinct, but previously undocumented, habitat preferences suggest that the disease in humans may be related to exposures to the primary reservoir species, C. musculinus, in border habitats rather than in crop fields...
  31. pmc Role of Cannomys badius as a natural animal host of Penicillium marneffei in India
    Harish Gugnani
    Department of Medical Mycology, University of Delhi, India
    J Clin Microbiol 42:5070-5. 2004
    ..This demonstrates the utility of an MLMT-based approach to elucidating the epidemiology of P. marneffei...
  32. ncbi Natural tick-borne encephalitis virus infection among wild small mammals in the southeastern part of western Siberia, Russia
    Valentina N Bakhvalova
    Institute of Systematics and Ecology of Animals, The Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
    Vector Borne Zoonotic Dis 6:32-41. 2006
    ..Taken together, the data suggest that small mammals may maintain TBEV as a persistent infection throughout the year...
  33. ncbi Pathogenesis of experimental vesicular stomatitis virus (New Jersey serotype) infection in the deer mouse (Peromyscus maniculatus)
    T E Cornish
    Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens, USA
    Vet Pathol 38:396-406. 2001
    ..The documentation of viremia in these animals suggests that they may have a role in the epidemiology of vector-borne vesicular stomatitis...
  34. ncbi Migration behaviour and pathogenesis of five ascarid nematode species in the Mongolian gerbil Meriones unguiculatus
    S Cho
    Department of Veterinary Parasitology, Azabu University, Fuchinobe 1 17 71, Sagamihara 229 8501, Japan
    J Helminthol 81:43-7. 2007
    ..Fatal neurological disturbances were observed in B. procyonis-infected gerbils, whereas irreversible non-fatal neurological symptoms were observed in the case of B. transfuga...
  35. doi Utilisation of rodent species by larvae and nymphs of hard ticks (Ixodidae) in two habitats in NE Poland
    Anna Paziewska
    University of Warsaw, Warsaw, Poland
    Exp Appl Acarol 50:79-91. 2010
    ..The impact of habitat change (in this case successional change following field abandonment) on tick densities is emphasised, and the role of Apodemus as an epidemiological bridge, linking woodland and field habitats, is highlighted...
  36. ncbi Rodents as shared indicators for zoonotic parasites of carnivores in urban environments
    L A Reperant
    Institute of Parasitology, University of Zurich, Winterthurerstrasse 266a, CH 8057 Zurich, Switzerland
    Parasitology 136:329-37. 2009
    ..These results highlight the potential value of rodents as shared indicators for these pathogens...
  37. ncbi PCR-based diagnosis for detection of Leishmania in skin and blood of rodents from an endemic area of cutaneous and visceral leishmaniasis in Brazil
    Fernanda S Oliveira
    Laboratório de Sistemática Bioquímica, Departamento de Bioquimica e Biologia Molecular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz FIOCRUZ, Rio de Janeiro, Brasil
    Vet Parasitol 129:219-27. 2005
    ..L.) chagasi in a naturally infected T. apereoides. The utility of filter paper as a substrate for PCR analyses and the efficacy of the procedure associated to the hybridization is emphasized...
  38. ncbi Seoul virus in patients and rodents from Beijing, China
    Shu Qing Zuo
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
    Am J Trop Med Hyg 78:833-7. 2008
    ..7% for one of the cases of HFRS--the human- and Rattus norvegicus-originated SEOV sequences--had only two silent substitutions, suggesting genetic analysis is an essential tool for "case-investigation."..
  39. ncbi Emergence and persistence of hantaviruses
    S L Klein
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Curr Top Microbiol Immunol 315:217-52. 2007
    ..In addition, we summarize all these complexities and provide suggestions for future research directions...
  40. doi Transmission efficiency of two flea species (Oropsylla tuberculata cynomuris and Oropsylla hirsuta) involved in plague epizootics among prairie dogs
    Aryn P Wilder
    Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
    Ecohealth 5:205-12. 2008
    ..tuberculata cynomuris abundance, and in September-October when O. hirsuta is common. Our findings may be useful in determining the timing of insecticidal dusting to slow plague transmission in black-tailed prairie dogs...
  41. pmc Recombination within and between species of the alpha proteobacterium Bartonella infecting rodents
    Anna Paziewska
    Department of Parasitology, Institute of Zoology, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02 096, Warsaw, Poland
    Microb Ecol 61:134-45. 2011
    ..Bartonella clades infecting Microtus were most frequently involved in recombination and were most frequently tip clades within the cladogram. The role of Microtus in influencing the frequency of Bartonella recombination remains unknown...
  42. ncbi Zoonotic reservoir of Babesia microti in Poland
    Grzegorz Karbowiak
    W Stefański Institute of Parasitology of Polish Academy of Sciences, 00 818 Warsaw, Poland
    Pol J Microbiol 53:61-5. 2004
    ..microti in Szczecin and Tri-City, the rate was 6.2-13.3%. The variation in B. microti prevalence in rodents and ticks is very changeable and determined by season, the interaction with other hemoparasites, host's age and local conditions...
  43. pmc Sympatric occurrence of 3 arenaviruses, Tanzania
    Joelle Gouy de Bellocq
    Evolutionary Ecology Group, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Emerg Infect Dis 16:692-5. 2010
    ..We found that 2 rodent species other than Mastomys natalensis mice carry arenaviruses. Analysis of 340 nt of the viral RNA polymerase gene showed sympatric occurrence of 3 distinct arenaviruses...
  44. pmc Contact heterogeneity in deer mice: implications for Sin Nombre virus transmission
    Christine A Clay
    Department of Biology, Westminster College, 1840 South 1300 East, Salt Lake City, UT 84105, USA
    Proc Biol Sci 276:1305-12. 2009
    ..Larger-bodied individuals appear to be the functional group with the greatest SNV transmission potential. Contrary to our predictions, transmission potential was not influenced by breeding condition or sex...
  45. pmc Analysis of wild-derived mice for Fv-1 and Fv-2 murine leukemia virus restriction loci: a novel wild mouse Fv-1 allele responsible for lack of host range restriction
    C A Kozak
    J Virol 55:281-5. 1985
    ..Only M. spretus was resistant to virus-induced splenomegaly and did not restrict replication of Friend virus helper murine leukemia virus. Genetic studies confirmed that this mouse carries the resistance allele at Fv-2...
  46. ncbi Flea diversity and infestation prevalence on rodents in a plague-endemic region of Uganda
    Gerald Amatre
    Uganda Virus Research Institute, Entebbe, Uganda
    Am J Trop Med Hyg 81:718-24. 2009
    ..Future studies are needed to determine whether flea abundance or species composition changes during epizootics when humans are most at risk of exposure...
  47. ncbi Antibody to sin nombre virus in rodents associated with peridomestic habitats in west central Montana
    A J Kuenzi
    Department of Biology, Montana Tech of the University of Montana, Butte 59701, USA
    Am J Trop Med Hyg 64:137-46. 2001
    ..Peridomestic settings presented higher concentrations of virus and may present a higher risk of human infection than do sylvan settings...
  48. pmc Delayed density-dependent prevalence of Sin Nombre virus infection in deer mice (Peromyscus maniculatus) in central and western Montana
    Scott Carver
    Department of Biology, Montana Tech of University of Montana, 1300 Park Street, Butte, Montana 59701, USA
    J Wildl Dis 47:56-63. 2011
    ..Our study suggests predicting local, human exposure risk to SNV in spring, based on deer mouse abundance in autumn, is unlikely to be a reliable public health tool, particularly at local scales...
  49. ncbi Changes in sin nombre virus antibody prevalence in deer mice across seasons: the interaction between habitat, sex, and infection in deer mice
    Jessica M C Pearce-Duvet
    Biology Department, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
    J Wildl Dis 42:819-24. 2006
    ..6, P = 0.05); and seropositive mice had more scars (t = 2.5, P = 0.02). We speculate nesting behavior could maintain SNV over the winter, whereas summer territoriality could be responsible for transmission...
  50. ncbi Factors affecting the component community structure of haemoparasites in common voles ( Microtus arvalis) from the Mazury Lake District region of Poland
    A Pawelczyk
    Department of Parasitology, Institute of Zoology, University of Warszawa, Miecznikowa 1 Street, 02 096 Warszawa, Poland
    Parasitol Res 92:270-84. 2004
    ....
  51. ncbi Seasonal variation in Sin Nombre virus infections in deer mice: preliminary results
    M Denise Dearing
    Department of Biology, University of Utah, Salt Lake City, Utah, USA
    J Wildl Dis 45:430-6. 2009
    ..Based on the results, coupled with those from the literature, we speculate that the majority of new infections may occur predominantly in the spring and that SNV may impair reproductive output of females...
  52. doi Detection of Dobrava-Belgrade hantavirus using recombinant-nucleocapsid-based enzyme-linked immunosorbent assay and SYBR Green-based real-time reverse transcriptase-polymerase chain reaction
    Viktoria Nemeth
    Virological Research Group, Faculty of Sciences, Institute of Biology, University of Pecs, Ifjúság út 6, 7624 Pecs, Hungary
    Arch Virol 156:1655-60. 2011
    ..We conclude that the prevalence of DOBV is much higher than previously anticipated. The simultaneous use of molecular and serological techniques provides a highly reliable way to detect hantavirus infections...
  53. doi First detection of Leishmania major in Rattus norvegicus from Fars Province, Southern Iran
    Mohammad Hossein Motazedian
    Department of Parasitology and Mycology, Shiraz University of Medical Sciences, Shiraz, Iran
    Vector Borne Zoonotic Dis 10:969-75. 2010
    ..norvegicus in Iran or elsewhere, the rodent can be considered as a possible reservoir in transmission of the disease in Fars Province, and it should be brought into consideration when planning for preventive measures...
  54. pmc Sangassou virus, the first hantavirus isolate from Africa, displays genetic and functional properties distinct from those of other murinae-associated hantaviruses
    Boris Klempa
    Institute of Virology, Helmut Ruska Haus, Charite Medical School, Berlin, Germany
    J Virol 86:3819-27. 2012
    ..These properties are unique within Murinae-associated hantaviruses and make the virus useful in comparative studies focusing on hantavirus pathogenesis...
  55. pmc Genetic evidence of Dobrava virus in Apodemus agrarius in Hungary
    J J Scharninghausen
    Texas A and M University, College Station 77843, USA
    Emerg Infect Dis 5:468-70. 1999
    ..The samples we isolated group with DOB samples previously isolated from A. flavicollis. This grouping may indicate host switching...
  56. ncbi Gastrointestinal helminth parasites of the black rat (Rattus rattus) in Abeokuta, southwest Nigeria
    C F Mafiana
    Department of Biological Sciences, University of Agriculture, Abeokuta, Ogun State, Nigeria
    J Helminthol 71:217-20. 1997
    ..3). Moniliformis moniliformis was the most common species encountered (39.2%) and had the highest mean intensity in both sexes (x=7.4+/-0.74). Considering the rat-man proximity, this finding has considerable public health implications...
  57. ncbi Variation in the helminth community structure in bank voles (Clethrionomys glareolus) from three comparable localities in the Mazury Lake District region of Poland
    J M Behnke
    School of Life and Environmental Sciences, University of Nottingham, University Park, UK
    Parasitology 123:401-14. 2001
    ....
  58. doi Molecular detection of Leishmania infantum in wild rodents (Rattus norvegicus) in Greece
    E Papadogiannakis
    Department of Veterinary Public Health, National School of Public Health, Athens, Greece
    Zoonoses Public Health 57:e23-5. 2010
    ..This is the first documented case of detection of L. infantum in R. norvegicus in Greece. The results of this preliminary study indicate that R. norvegicus is unlikely to be a reservoir for Leishmania parasites in Greece...
  59. pmc Population density and seasonality effects on Sin Nombre virus transmission in North American deermice (Peromyscus maniculatus) in outdoor enclosures
    Karoun H Bagamian
    Population Biology, Ecology, and Evolution Program, Emory University, Atlanta, Georgia, United States of America
    PLoS ONE 7:e37254. 2012
    ..Seasonality may have a stronger influence on disease transmission dynamics than host population density, and density effects cannot be considered independent of seasonality...
  60. ncbi Characterization of Leishmania infection in rodents from endemic areas of the Islamic Republic of Iran
    M Mohebali
    School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran
    East Mediterr Health J 10:591-9. 2004
    ..7% of 504 rodents. Two species were positive on culture; promastigotes isolated from Mer. persicus were characterized as L. donovani zymodeme LON50 and from Mesocricetus auratus as L. infantum LON49...
  61. ncbi Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato
    M B Castro
    Vector-Borne Disease Section, Division of Communicable Disease Control, California Department of Health Services, Santa Rosa 95404, USA
    Am J Trop Med Hyg 65:261-7. 2001
    ..phagocytophila. Borrelia burgdorferi, the agent of Lyme disease, was cultured from ear punch biopsies from six of seven E. phagocytophila seropositive and one of four seronegative wood rats...
  62. doi Isolation of Leptospira interrogans from suburban rats in Tandil, Buenos Aires, Argentina
    E Scialfa
    División Zoonosis Rurales, España 770, 7300 Azul, Provincia de Buenos Aires, Argentina
    Rev Argent Microbiol 42:126-8. 2010
    ..These findings showed a high density of suburban rodents highly infected with pathogenic leptospira, sharing environment in close contact with humans with evidence of leptospiral disease...
  63. ncbi Serosurvey of wild rodents for hantaviruses in Panama, 2000-2002
    Jorge Salazar-Bravo
    Department of Biological Sciences, Texas Tech University, Lubbock, Texas 79409, USA
    J Wildl Dis 40:103-9. 2004
    ..However, given the total number of animals tested, the role of these rodent species in the epidemiology and epizootiology of hantavirus infections remains unclear...
  64. doi Human leptospirosis cases and the prevalence of rats harbouring Leptospira interrogans in urban areas of Tokyo, Japan
    Nobuo Koizumi
    Department of Bacteriology, National Institute of Infectious Diseases, Shinjuku ku, Tokyo 162 8640, Japan
    J Med Microbiol 58:1227-30. 2009
    ..Antibodies against these serovars and their DNA were detected in the patients. This suggests that rats are important reservoirs of leptospirosis, and that rat-borne leptospires occur in urban areas of Tokyo...
  65. ncbi Parasitic zoonoses at the rodent-captive primate-human health interface
    Hany M Elsheikha
    School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, United Kingdom
    J Egypt Soc Parasitol 39:447-60. 2009
    ..Finally, priorities for future research are identified, including identifying those parasites for which multi-host interaction is likely to have the greatest impact...
  66. ncbi Medium-term temporal stability of the helminth component community structure in bank voles (Clethrionomys glareolus) from the Mazury Lake District region of Poland
    A Bajer
    Department of Parasitology, Institute of Zoology, University of Warszawa, ul Miecznikowa 1, 02 096 Warszawa, Poland
    Parasitology 130:213-28. 2005
    ....
  67. ncbi Testosterone depresses innate and acquired resistance to ticks in natural rodent hosts: a force for aggregated distributions of parasites
    V L Hughes
    Department of Zoology, University of Oxford, UK
    J Parasitol 87:49-54. 2001
    ..The lowest innate and acquired resistance to tick feeding occurs in that fraction of the host population, i.e., sexually active males, most actively involved in the transmission of both Babesia microti and Borrelia burgdorferi s.l...
  68. ncbi Biotic and abiotic effects on endoparasites infecting Dipodomys and Perognathus species
    K H Decker
    The University of New Mexico, Department of Biology, Albuquerque 87131 1091, USA
    J Parasitol 87:300-7. 2001
    ..The parasite prevalences in these rodents on the SNWR vary in independent and complex ways...
  69. ncbi Sylvatic plague reduces genetic variability in black-tailed prairie dogs
    Kristie M Trudeau
    Department of Biology, University of South Dakota, Vermillion, South Dakota 57069, USA
    J Wildl Dis 40:205-11. 2004
    ..Conservation of genetic variability in black-tailed prairie dogs will require the preservation of both large and small colony complexes and the gene flow amonog them...
  70. ncbi Genetic characterization of new Dobrava hantavirus isolate from Greece
    Kirill Nemirov
    Department of Virology, Haartman Institute, University of Helsinki, Finland
    J Med Virol 69:408-16. 2003
    ....
  71. pmc Common reservoirs for Penicillium marneffei infection in humans and rodents, China
    Cunwei Cao
    The First Affiliated Hospital of Guangxi Medical University, Nanning, People s Republic of China
    Emerg Infect Dis 17:209-14. 2011
    ..Humans and bamboo rats are sampling an as-yet undiscovered common reservoir of infection, or bamboo rats are a vector for human infections by acting as amplifiers of infectious dispersal stages...
  72. doi Sin Nombre hantavirus decreases survival of male deer mice
    Angela D Luis
    Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, USA
    Oecologia 169:431-9. 2012
    ....
  73. ncbi Detection of Dobrava hantaviruses in Apodemus agrarius mice in the Transdanubian region of Hungary
    Ferenc Jakab
    Institute of Biology, University of Pecs, Pecs, Hungary
    Virus Res 128:149-52. 2007
    ..agrarius mice in Slovenia. Based on our new data from the region we concluded that extended reservoir studies would be necessary in the future...
  74. doi Patterns of orthopox virus wild rodent hosts in South Germany
    Sandra Essbauer
    Bundeswehr Institute of Microbiology, Munich, Germany
    Vector Borne Zoonotic Dis 9:301-11. 2009
    ..We here show for the first time that A. flavicollis beside M. glareolus is a hypothetic host for CPXV, and that there are big geographical and spatial variations concerning the seroprevalence in rodent populations in South Germany...
  75. ncbi Density-dependent host selection in ectoparasites: an application of isodar theory to fleas parasitizing rodents
    Boris R Krasnov
    Ramon Science Centre and Mitrani Department of Desert Ecology, Jacob Blaustein Institute for Desert Research, Ben Gurion University of the Negev, P O Box 194, 80600 Mizpe Ramon, Israel
    Oecologia 134:365-72. 2003
    ..The results of the application of the isodar theory suggest that ectoparasites, like other animals, behave as if they are able to make choices and decisions that favour environments in which their reproductive benefit is maximized...
  76. ncbi Host-habitat relations as an important determinant of spatial distribution of flea assemblages (Siphonaptera) on rodents in the Negev Desert
    B R Krasnov
    Ramon Science Center, Ben Gurion University of the Negev, Mizpe Ramon, Israel
    Parasitology 114:159-73. 1997
    ..Each of the ordination axes corresponded with a change in flea species composition. The directions of these changes were (1) among-hosts within a habitat and (2) among-habitats within a host...
  77. ncbi Ectoparasites of commensal rodents in Talkha Center, Dakahlia Governorate, Egypt
    Gamal A El Kady
    Department of Plant Protection, Faculty of Agriculture, Suez Canal University
    J Egypt Soc Parasitol 37:825-33. 2007
    ..69 lice/rat), Mites N = 165 (1.2 mite/rat) and larva of ticks N=16 (0.12 tick/rat). No doubt, rodents and their ectoparasites played a serious role in spreading and transmission of zoonotic diseases to human and animal...
  78. ncbi Incidence from coincidence: patterns of tick infestations on rodents facilitate transmission of tick-borne encephalitis virus
    S E Randolph
    Department of Zoology, University of Oxford, UK
    Parasitology 118:177-86. 1999
    ..This identifies the particular climatic factors that permit such patterns of tick seasonal dynamics as the primary predictors for the focal distribution of TBE...
  79. ncbi Bartonella grahamii infecting rodents display high genetic diversity over short geographic distances
    C Ehrenborg
    Department of Medical Sciences, Section for Infectious Diseases, Uppsala University Hospital, Uppsala, Sweden
    Ann N Y Acad Sci 990:233-5. 2003
  80. ncbi Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.)
    D Bermond
    Institut de Bacteriologie de la Faculte de Medecine, Universite Louis Pasteur, H pitaux Universitaires de Strasbourg, France
    Int J Syst Evol Microbiol 50:1973-9. 2000
    ..The name Bartonella birtlesii is proposed for the new species. The type strain of B. birtlesii sp. nov. is IBS 325T (= CIP 106294T = CCUG 44360T)...
  81. ncbi Seasonal studies on commensal rats and their ectoparasites in a rural area of Egypt: the relationship of ectoparasites to the species, locality, and relative abundance of the host
    S Soliman
    Department of Zoology, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt
    J Parasitol 87:545-53. 2001
    ..Seasonal changes in the general indices of some ectoparasites paralleled seasonal changes in the relative abundance of their rat hosts...
  82. pmc Rodent and flea abundance fail to predict a plague epizootic in black-tailed prairie dogs
    Robert Jory Brinkerhoff
    Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado 80309 0334, USA
    Vector Borne Zoonotic Dis 10:47-52. 2010
    ....
  83. doi A survey of rodent-borne pathogens carried by wild-caught Norway rats: a potential threat to laboratory rodent colonies
    Judith D Easterbrook
    The W Harry Feinstone Department of Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lab Anim 42:92-8. 2008
    ..8%), were identified in wild-caught rats. The risk of pathogen transmission from wild-caught rats to laboratory colonies needs to be mitigated by minimizing exposures rather than assuming wild animals represent a minimal hazard...
  84. ncbi Comparison of the in vitro susceptibility of rodent isolates of Pseudomonas aeruginosa and Pasteurella pneumotropica to enrofloxacin
    Hiraku Sasaki
    Animal Research Center, Tokyo Medical University, Shinjuku, Tokyo, Japan
    J Vet Diagn Invest 19:557-60. 2007
    ..These results indicated that the enrofloxacin susceptibility of P. pneumotropica was higher than that of Ps. aeruginosa, and that the enrofloxacin treatment might not affect the susceptibility of Ps. aeruginosa...
  85. ncbi Sympatric Ixodes trianguliceps and Ixodes ricinus ticks feeding on field voles (Microtus agrestis): potential for increased risk of Anaplasma phagocytophilum in the United Kingdom?
    K J Bown
    Department of Veterinary Pathology, University of Liverpool, Liverpool, UK
    Vector Borne Zoonotic Dis 6:404-10. 2006
    ..trianguliceps, which may alone maintain endemic cycles, and exophilic I. ricinus ticks, which could act as a bridge vector and transmit infections to humans and domesticated animals...
  86. pmc Principal host relationships and evolutionary history of the North American arenaviruses
    Maria N B Cajimat
    University of Texas Medical Branch, Graduate School of Biomedical Sciences, Microbiology and Immunology Graduate Program, Galveston, TX 77555 1019, USA
    Virology 367:235-43. 2007
    ....
  87. ncbi Eimeria-parasites are associated with a lowered mother's and offspring's body condition in island and mainland populations of the bank vole
    H Hakkarainen
    Section of Ecology, Department of Biology, University of Turku, FIN 20014 Turku, Finland
    Parasitology 134:23-31. 2007
    ..Our data are consistent with the idea that infection with coccidian parasites may be one of the factors responsible for declining host populations in small, isolated populations...
  88. pmc Contrasting dynamics of Bartonella spp. in cyclic field vole populations: the impact of vector and host dynamics
    S Telfer
    School of Biological Sciences, University of Liverpool, Biosciences Building, Liverpool L69 7LB, UK
    Parasitology 134:413-25. 2007
    ..possibly reflecting the importance of flea exchange between hosts. However, even closely related species showed quite different dynamics, emphasising that other factors such as population age structure can impact on zoonotic risk...
  89. ncbi Isolation and characterization of hantavirus carried by Apodemus peninsulae in Jilin, China
    Yong zhen Zhang
    Department of Hemorrhagic Fever, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, Beijing 102206, China
    J Gen Virol 88:1295-301. 2007
    ..However, the viruses detected in A. peninsulae in China are genetically different from those detected in A. peninsulae in other countries. These data suggest that A. peninsulae is also a natural host for HTNV in north-eastern China...
  90. ncbi Differential exposure to Anaplasma phagocytophilum in rodent species in northern California
    Janet E Foley
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vector Borne Zoonotic Dis 8:49-55. 2008
    ..The spatial clustering of exposed animals suggests interesting underlying spatially heterogeneous environmental variables that could facilitate the persistence of A. phagocytophilum in nature...
  91. ncbi Fox squirrel (Sciurus niger) associations with West Nile virus
    J Jeffrey Root
    United States Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado 80521, USA
    Am J Trop Med Hyg 76:782-4. 2007
    ..In addition, urine samples (N = 17) opportunistically collected from fox squirrels were negative for WNV RNA. Results indicate that seroconversions can be observed in fox squirrels during low WNV transmission years...
  92. doi A newly discovered Anaplasma phagocytophilum variant in rodents from southeastern China
    Lin Zhan
    Beijing Institute of Microbiology, and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 20 Dong Da Street, Fengtai District, Beijing 100071, PR China
    Vector Borne Zoonotic Dis 8:369-80. 2008
    ..phagocytophilum sequences,as were msp4 and groESL. These findings indicate that the newly discovered agent represents a novel A. phagocytophilum variant...
  93. ncbi Isolation and genetic characterization of hantaviruses carried by Microtus voles in China
    Yang Zou
    Department of Hemorrhagic Fever, Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    J Med Virol 80:680-8. 2008
    ..maximowiczii is the natural host of KHAV including Yakeshi-Mm strains. Thus, in addition to Hantaan, Seoul, Dabieshan and Puumala-like Hokkaido viruses, at least two other hantaviruses, namely KHAV and VLAV, are circulating in China...
  94. ncbi A role for vector-independent transmission in rodent trypanosome infection?
    A Smith
    Population Biology Research Group, School of Biological Sciences, Bioscience Building, University of Liverpool, Merseyside L69 7ZB, UK
    Int J Parasitol 36:1359-66. 2006
    ..The possibility that the importance of such transmission routes may have been underestimated in 'vector-borne' infections more generally is discussed...
  95. ncbi Diabetes and myocarditis in voles and lemmings at cyclic peak densities--induced by Ljungan virus?
    Bo Niklasson
    Apodemus AB, Grevgatan 38, 114 53, Stockholm, Sweden
    Oecologia 150:1-7. 2006
    ..Increased stress at peak densities is thought to be an important trigger for the development of disease, as the occurrence of disease in laboratory mice has been found to be triggered by introducing stress to LV-infected animals...
  96. ncbi Predictive thresholds for plague in Kazakhstan
    Stephen Davis
    Danish Pest Infestation Laboratory, Skovbrynet 14, DK 2800 Kongens Lyngby, Denmark
    Science 304:736-8. 2004
    ..We parameterized predictive models that should reduce the costs of plague surveillance in central Asia and thereby encourage its continuance...
  97. ncbi Experimental infection of dusky-footed wood rats (Neotoma fuscipes) with Ehrlichia phagocytophila sensu lato
    Janet E Foley
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616 8782, USA
    J Wildl Dis 38:194-8. 2002
    ..These data confirm that wood rats are susceptible to E. phagocytophila s.l., may develop prolonged infection without clinical ehrlichiosis, and may play a role in maintaining E. phagocytophila s.l. in nature...
  98. ncbi The musk rat (Ondatra zibethicus) as intermediate host of cestodes in the Netherlands
    Fred H M Borgsteede
    Animal Sciences Group Wageningen UR, Division Infectious Diseases, PO Box 65, 8200 AB Lelystad, The Netherlands
    Vet Parasitol 117:29-36. 2003
    ..Although E. multilocularis infections were exceptional, it is expected that with a rise in the number of infected foxes in the Netherlands the number of infected musk rats will increase...
  99. ncbi Hantavirus antibody occurrence in bank voles (Clethrionomys glareolus) during a vole population cycle
    Gert E Olsson
    Department of Animal Ecology, Swedish University of Agricultural Sciences, SE 901 83 Umea, Sweden
    J Wildl Dis 39:299-305. 2003
    ..This would imply that the risk of Puumala virus exposure to conspecifics and humans is habitat and site dependent with a temporal component...
  100. ncbi Rapid and simple method for screening wild rodents for antibodies to Sin Nombre hantavirus
    Joyce Yee
    Department of Pathology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    J Wildl Dis 39:271-7. 2003
    ..The test can be used to detect rodents positive for SNV antibody while they are in traps. We show that results with the SIA have excellent concordance with western blot and reverse transcriptase polymerase chain reaction tests...
  101. ncbi Evidence of the presence of Seoul virus in Cambodia
    Jean Marc Reynes
    Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Royaume du Cambodge, Cambodia
    Microbes Infect 5:769-73. 2003
    ..However, the Cambodian Seoul virus sequences clustered within two different phylogenetic lineages, one associated with R. rattus and the other with R. norvegicus...

Research Grants83

  1. SCREENING MICE FOR AUDITORY & NEUROBEHAVIORAL PHENOTYPES
    JAMES WILLOTT; Fiscal Year: 2002
    ..Johnson. This will be accompanied by development of an easy-to-use software/ hardware package that will integrate all screening techniques in a single, serial protocol for use on individual mice. ..
  2. Cognitive Function in SLE (COGNITION)
    ROBIN BREY; Fiscal Year: 2007
    ..The information that will be gained from this study is essential for the successful discovery of biological processes that impact on cognitive function in SLE that could be potentially amenable to disease-reversing therapies. ..
  3. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2007
    ..The ultimate goal is to develop new approaches for amelioration and treatment ofpresbycusis and other hearing disorders. [unreadable] [unreadable]..
  4. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2007
    ..In addition, these studies will provide information about perturbations in host physiology and gene expression induced by murine parvoviruses, and basic scientific information about parvovirus host interaction. ..
  5. Psychosocial modulation of mammary carcinogenesis
    Jason Yee; Fiscal Year: 2007
    ..As such, these studies will also allow an estimation of the proportion of the racial disparity in breast cancer that can be explained by social inequalities. [unreadable] [unreadable] [unreadable] [unreadable]..
  6. CRYSTAL STRUCTURE OF A YERSINIA TYROSINE PHOSPHATASE
    MARK SAPER; Fiscal Year: 1993
    ..The pathogenic bacterium Yersinia is responsible for a range of human and rodent diseases from diarrhea to the bubonic plague...
  7. Fixed Equipment for DDB Animal Resource
    MARVIN SWINDLE; Fiscal Year: 2009
    ..The requested equipment will provide protection against the spread of complicating rodent diseases in the facilities.
  8. 5 NUCLEASE ASSAYS FOR RODENT HEALTH MONITORING
    David Besselsen; Fiscal Year: 2001
    ..FFPNA will greatly enhance the diagnostic capabilities for routine health monitoring of laboratory rodents and will provide a viable, cost-effective alternative for RAP testing. ..
  9. 5 NUCLEASE ASSAYS FOR RODENT HEALTH MONITORING
    David Besselsen; Fiscal Year: 2000
    ..FFPNA will greatly enhance the diagnostic capabilities for routine health monitoring of laboratory rodents and will provide a viable, cost-effective alternative for RAP testing. ..
  10. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2006
    ..In addition, these studies will provide information about perturbations in host physiology and gene expression induced by murine parvoviruses, and basic scientific information about parvovirus host interaction. ..
  11. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2003
    ..In addition, these studies will provide information about perturbations in host physiology and gene expression induced by murine parvoviruses, and basic scientific information about parvovirus host interaction. ..
  12. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2005
    ..In addition, these studies will provide information about perturbations in host physiology and gene expression induced by murine parvoviruses, and basic scientific information about parvovirus host interaction. ..
  13. 5 NUCLEASE ASSAYS FOR RODENT HEALTH MONITORING
    David Besselsen; Fiscal Year: 2002
    ..FFPNA will greatly enhance the diagnostic capabilities for routine health monitoring of laboratory rodents and will provide a viable, cost-effective alternative for RAP testing. ..
  14. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2004
    ..In addition, these studies will provide information about perturbations in host physiology and gene expression induced by murine parvoviruses, and basic scientific information about parvovirus host interaction. ..
  15. 5 NUCLEASE ASSAYS FOR RODENT HEALTH MONITORING
    David Besselsen; Fiscal Year: 1999
    ..FFPNA will greatly enhance the diagnostic capabilities for routine health monitoring of laboratory rodents and will provide a viable, cost-effective alternative for RAP testing. ..
  16. UW Oshkosh Animal Facility Improvement
    DANA VAUGHAN; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  17. Cellular and Molecular Mediators of Hantavirus Infection
    Sabra Klein; Fiscal Year: 2005
    ..abstract_text> ..
  18. Cellular and Molecular Mediators of Hantavirus Infection
    Sabra Klein; Fiscal Year: 2003
    ..abstract_text> ..
  19. Cellular and Molecular Mediators of Hantavirus Infection
    Sabra Klein; Fiscal Year: 2004
    ..abstract_text> ..
  20. COMPARATIVE MEDICAL SCIENTIST POSTDOCTORAL TRAINING
    Trenton Schoeb; Fiscal Year: 2006
    ..abstract_text> ..
  21. Cellular and Molecular Mediators of Hantavirus Infection
    Sabra Klein; Fiscal Year: 2006
    ..abstract_text> ..
  22. Mark I Model 68A Rodent/Cell line Gamma Irradiator
    Sanford Feldman; Fiscal Year: 2004
    ....
  23. Liposomal Opioids Extend Analgesia in Laboratory Animals
    Lisa Krugner Higby; Fiscal Year: 2007
    ..If proven efficacious, these analgesic regimens would lead to a significant change in the post-surgical care of animals used in biomedical research and veterinary medicine. ..
  24. BACTERIAL MODULATION OF LUNG INFLAMMATORY RESPONSE
    Thomas Russo; Fiscal Year: 2004
    ..g. hemolysin) and bacterially induced host response elements in directly mediating the pathogenesis of lung injury. ..
  25. IMMUNOGENETICS--TARGET ORGAN DAMAGE IN IMMUNE NEPHRITIS
    Chandra Mohan; Fiscal Year: 2005
    ..A better understanding of the genetic and cellular basis of target organ damage could potentially lead to more targeted therapies for nephritis in the future. ..
  26. LUPUS GENES AND B-CELL SIGNALING
    Chandra Mohan; Fiscal Year: 2009
    ..Uncovering essential nodes in lupus pathogenesis using these novel genetic models are likely to pave the way towards more effective therapy in lupus targeting critical signaling nodes. ..
  27. Psychosocial modulation of mammary carcinogenesis
    Jason Yee; Fiscal Year: 2008
    ..As such, these studies will also allow an estimation of the proportion of the racial disparity in breast cancer that can be explained by social inequalities. [unreadable] [unreadable] [unreadable] [unreadable]..
  28. Pathogenesis of TSC2-Related Tumors
    Raymond Yeung; Fiscal Year: 2005
    ..The results of these experiments will enable us to better understand the pathogenesis of tumor development and their clinical sequelae in tuberous sclerosis and related disorders. ..
  29. Host response to Chlamydia genital infection in the male
    Roger Rank; Fiscal Year: 2005
    ..abstract_text> ..
  30. Studies of Collagen Gene Regulation in Two Murine Models
    Stephen Clark; Fiscal Year: 2005
    ....
  31. Mycobacteria in metalworking fluids
    Jagjit Yadav; Fiscal Year: 2007
    ..abstract_text> ..
  32. Biennial Meeting of Chlamydia Basic Research Society
    Roger Rank; Fiscal Year: 2007
    ..abstract_text> ..
  33. MOLECULAR BASIS OF BORRELIA PATHOGENESIS
    Alan Barbour; Fiscal Year: 2007
    ..We will evaluate this by developing models that are based on currently available data about infection dynamics and then use these early models' deficiencies to direct us in further experimentation and modelbuilding. ..
  34. Genetics of Alopecia Areata in the C3H/HeJ Mouse
    JOHN PAUL SUNDBERG; Fiscal Year: 2010
    ....
  35. Host response to Chlamydia genital infection in the male
    Roger Rank; Fiscal Year: 2006
    ..abstract_text> ..
  36. IMMUNOGENETICS--TARGET ORGAN DAMAGE IN IMMUNE NEPHRITIS
    Chandra Mohan; Fiscal Year: 2004
    ..A better understanding of the genetic and cellular basis of target organ damage could potentially lead to more targeted therapies for nephritis in the future. ..
  37. PATHOLOGY OF THE LABORATORY MOUSE
    John Sundberg; Fiscal Year: 2005
    ..The Workshop will accommodate 16 participants who will have an opportunity to interact with a group of prominent mouse pathologists and geneticists from both TJL, and other leading institutions. ..
  38. VEGF regulation of surfactant proteins in preventing RSV
    DAVID MEYERHOLZ; Fiscal Year: 2005
    ....
  39. Pacific-Southwest Ctr for Biodefense & Emerg Infect Dis*
    Alan Barbour; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  40. BACTERIAL MODULATION OF LUNG INFLAMMATORY RESPONSE
    Thomas Russo; Fiscal Year: 2003
    ..g. hemolysin) and bacterially induced host response elements in directly mediating the pathogenesis of lung injury. ..
  41. IMPACT OF LUPUS SUSCEPTIBILITY LOCI ON B CELL TOLERANCE
    Chandra Mohan; Fiscal Year: 2002
    ....
  42. CANCER SUSCEPTIBILITY IN AN ANIMAL MODEL
    Raymond Yeung; Fiscal Year: 2000
    ..Appreciation of these 'modifier' genes will impart new knowledge about the interplay between genes and environment during the development of complex diseases such as cancer. ..
  43. PREDICTORS OF NEUROPSYCHIATRIC SLE
    ROBIN BREY; Fiscal Year: 2000
    ..The information gained will bridge important gaps in our knowledge about NS involvement in SLE and will lead to new hypothesis-driven studies of etiopathogenesis and treatment. ..
  44. MODULATION OF AGE RELATED CHANGES IN THE AUDITORY SYSTEM
    JAMES WILLOTT; Fiscal Year: 2000
    ..g., hearing-aids) is commonly given to presbycusis patients and others with sensorineural hearing loss, determining the effects of AAEs (good or bad) on the auditory system has great potential clinical importance. ..
  45. IMPACT OF LUPUS SUSCEPTIBILITY LOCI ON B CELL TOLERANCE
    Chandra Mohan; Fiscal Year: 2001
    ....
  46. PATHOGENESIS OF TSCE-RELATED TUMORS IN THE EKER RAT
    Raymond Yeung; Fiscal Year: 2000
    ..Creating this network of information about tuberin and its interacting proteins will facilitate our long-term objective of identifying therapeutic targets that will benefit those who suffer from these devastating diseases. ..
  47. WORLD REFERENCE CENTER FOR ARBOVIRUSES
    Robert Tesh; Fiscal Year: 2000
    ..Training professional and technical personnel from any region of the world in arbovirus techniques, and 6. Dissemination of information on arbovirus taxonomy, diagnostic techniques and disease outbreaks. ..
  48. PREDICTORS OF NEUROPSYCHIATRIC SLE
    ROBIN BREY; Fiscal Year: 1999
    ..The information gained will bridge important gaps in our knowledge about NS involvement in SLE and will lead to new hypothesis-driven studies of etiopathogenesis and treatment. ..
  49. ECOLOGY OF EMERGING ARENAVIRUSES IN SOUTHWESTERN U S
    CHARLES FULHORST; Fiscal Year: 1999
    ..The project is of 3 years duration, consists of both field and laboratory studies, and involves the disciplines of virology, pathology, molecular biology, genetics, mammalogy, ecology and epidemiology. ..
  50. BIOLOGY AND CONTROL OF LYME DISEASE BORRELIA
    Alan Barbour; Fiscal Year: 2000
    ..burgdorferi, its transmission, and reservoir host immunize responses. The results may also have relevance for the control of other vector-bone zoonotic diseases and perhaps for development of novel methods for vaccine delivery. ..
  51. PREDICTORS OF NEUROPSYCHIATRIC SLE
    ROBIN BREY; Fiscal Year: 1999
    ..The information gained will bridge important gaps in our knowledge about NS involvement in SLE and will lead to new hypothesis-driven studies of etiopathogenesis and treatment. ..
  52. CANCER SUSCEPTIBILITY IN AN ANIMAL MODEL
    Raymond Yeung; Fiscal Year: 2002
    ..Appreciation of these 'modifier' genes will impart new knowledge about the interplay between genes and environment during the development of complex diseases such as cancer. ..
  53. Epidemiology of Yellow Fever in the Americas
    Robert Tesh; Fiscal Year: 2003
    ..Most of the work will be done in laboratories at the University of Texas Medical Branch, Center for Tropical Diseases; but a small portion will be done at the Evandro Chagas Institute in Belem, Brazil. ..
  54. CANCER SUSCEPTIBILITY IN AN ANIMAL MODEL
    Raymond Yeung; Fiscal Year: 2003
    ..Appreciation of these 'modifier' genes will impart new knowledge about the interplay between genes and environment during the development of complex diseases such as cancer. ..
  55. High fat feeding and intramyocellular lipid abnormality
    ZengKui Guo; Fiscal Year: 2003
    ..Thus, the proposed research will improve the understanding of the mechanism of insulin resistance and imcTG abnormalities in the obese rat that will benefit investigation of human obesity. ..
  56. Studies of Collagen Gene Regulation in Two Murine Models
    Stephen Clark; Fiscal Year: 2003
    ....
  57. Molecular Analysis of Mycobacteria in Cutting Fluids
    Jagjit Yadav; Fiscal Year: 2002
    ..The resulting information will help NORA's objectives by providing practical methods for microbial exposure assessment and database for developing intervention strategies related to MWF exposures. ..
  58. BACTERIAL MODULATION OF LUNG INFLAMMATORY RESPONSE
    Thomas Russo; Fiscal Year: 2002
    ..g. hemolysin) and bacterially induced host response elements in directly mediating the pathogenesis of lung injury. ..
  59. Candidate Gene Analysis in murine Lupus
    Chandra Mohan; Fiscal Year: 2002
    ..Significance: These experiments have the potential to uncover the identity of a lupus susceptibility gene on murine chromosome 4, that potentially impacts B-cell hyperactivity, pathogenic ANA formation. and end-organ disease. ..
  60. XENOBIOTIC-OXIDIZING P450 SYSTEM IN A WHITE ROT FUNGUS
    Jagjit Yadav; Fiscal Year: 2002
    ..chrysosporium constructed for this purpose, and/or in vitro assays using expressed enzymes. Optimized P450 conditions and strains will be tested in bench top models of bioremediation. ..
  61. BIOLOGY AND CONTROL OF LYME DISEASE BORRELIA
    Alan Barbour; Fiscal Year: 2002
    ..burgdorferi, its transmission, and reservoir host immunize responses. The results may also have relevance for the control of other vector-bone zoonotic diseases and perhaps for development of novel methods for vaccine delivery. ..
  62. DEVELOPMENT OF A LARGE ANIMAL TUMOR MODEL FOR ASSESSING GVL IMMUNOTHERAPY
    Raimon Duran Struuck; Fiscal Year: 2008
    ..Dr. Duran-Struuck will be exposed to all of these disciplines as his project progresses. ..
  63. DEVELOPMENT OF A LARGE ANIMAL TUMOR MODEL FOR ASSESSING GVL IMMUNOTHERAPY
    Raimon Duran Struuck; Fiscal Year: 2007
    ..Dr. Duran-Struuck will be exposed to all of these disciplines as his project progresses. ..
  64. Pacific-Southwest Ctr for Biodefense & Emerg Infect Dis*
    Alan Barbour; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  65. MOLECULAR BASIS OF BORRELIA PATHOGENESIS
    Alan Barbour; Fiscal Year: 2008
    ..We will evaluate this by developing models that are based on currently available data about infection dynamics and then use these early models' deficiencies to direct us in further experimentation and modelbuilding. ..
  66. BIOLOGY AND CONTROL OF LYME DISEASE BORRELIA
    Alan Barbour; Fiscal Year: 2004
    ..burgdorferi, its transmission, and reservoir host immunize responses. The results may also have relevance for the control of other vector-bone zoonotic diseases and perhaps for development of novel methods for vaccine delivery. ..
  67. BIOLOGY AND CONTROL OF LYME DISEASE BORRELIA
    Alan Barbour; Fiscal Year: 2003
    ..burgdorferi, its transmission, and reservoir host immunize responses. The results may also have relevance for the control of other vector-bone zoonotic diseases and perhaps for development of novel methods for vaccine delivery. ..
  68. BIOLOGY AND CONTROL OF LYME DISEASE BORRELIA
    Alan Barbour; Fiscal Year: 2001
    ..burgdorferi, its transmission, and reservoir host immunize responses. The results may also have relevance for the control of other vector-bone zoonotic diseases and perhaps for development of novel methods for vaccine delivery. ..
  69. Purchase of Ventilated Caging Systems and Workstations
    Debra Hickman; Fiscal Year: 2006
    ..We currently have 5 rooms that house rodents in ventilated filter-top caging but do not have access to a workstation. ..
  70. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2008
    ..The ultimate goal is to develop new approaches for amelioration and treatment ofpresbycusis and other hearing disorders. [unreadable] [unreadable]..
  71. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2006
    ..The ultimate goal is to develop new approaches for amelioration and treatment ofpresbycusis and other hearing disorders. [unreadable] [unreadable]..
  72. SCREENING MICE FOR AUDITORY & NEUROBEHAVIORAL PHENOTYPES
    JAMES WILLOTT; Fiscal Year: 2000
    ..Johnson. This will be accompanied by development of an easy-to-use software/ hardware package that will integrate all screening techniques in a single, serial protocol for use on individual mice. ..
  73. SCREENING MICE FOR AUDITORY & NEUROBEHAVIORAL PHENOTYPES
    JAMES WILLOTT; Fiscal Year: 2001
    ..Johnson. This will be accompanied by development of an easy-to-use software/ hardware package that will integrate all screening techniques in a single, serial protocol for use on individual mice. ..
  74. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2004
    ..The ultimate goal is to develop new approaches for amelioration and treatment ofpresbycusis and other hearing disorders. ..
  75. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2005
    ..The ultimate goal is to develop new approaches for amelioration and treatment ofpresbycusis and other hearing disorders. ..