Genomes and Genes
Summary: Diseases of animals within the order PRIMATES. This term includes diseases of Haplorhini and Strepsirhini.
Publications174 found, 100 shown here
- SIV-associated lymphomas in rhesus monkeys (Macaca mulatta) in comparison with HIV-associated lymphomasK Kahnt
German Primate Center, Gottingen
Vet Pathol 39:42-55. 2002..The present primate model represents a suitable animal model for studying the pathogenesis of AIDS-associated lymphomas...
- Identification of a human population infected with simian foamy virusesW Heneine
HIV and Retrovirology Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Nat Med 4:403-7. 1998..The infecting SFV originated from an African green monkey (one person) and baboons (three people). These infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections...
- Identification of recombination in the envelope gene of simian foamy virus serotype 2 isolated from Macaca cyclopisTeresa A Galvin
Laboratory of Retroviruses, Division of Viral Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, Maryland, USA
J Virol 87:8792-7. 2013..The results identify a potential region of neutralization in SFVs and demonstrate recombination between genetically divergent foamy viruses. ..
- Simian foamy virus infection in humans: prevalence and managementArifa S Khan
Laboratory of Retrovirus Research, Division of Viral Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
Expert Rev Anti Infect Ther 7:569-80. 2009..These steps will help prevent the emergence of a novel pathogen and reduce the risk of transmission of another potential pathogenic human retrovirus...
- Cross-species transmission of simian foamy virus to humans in rural Gabon, Central AfricaAugustin Mouinga-Ondeme
Unité de Rétrovirologie, Centre International de Recherches Medicales de Franceville, Franceville, Gabon
J Virol 86:1255-60. 2012..All but one were infected with ape SFV. We thus found novel SFV strains in NHPs in Gabon and high cross-species transmission of SFVs from gorilla bites...
- Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx)Cristian Apetrei
Center for Vaccine Research of the University of Pittsburgh, 9044 Biological Science Tower 3, 3501 Fifth Avenue, Pittsburgh, PA 15261, USA
J Virol 85:13077-87. 2011..Overall, these findings recapitulate previous observations in SIV-infected SMs and AGMs and lend further evidence to the hypothesis that low levels of immune activation protect natural SIV hosts from disease progression...
- Hepatitis B virus infection in non-human primatesP Sa-nguanmoo
Center of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Acta Virol 53:73-82. 2009..Enhanced awareness of prevalence, genetic relatedness and evolution of non-human primate HBVs will help prevent further spread and cross-transmission of these viruses between humans and non-human primates...
- Cross-species pathogen transmission and disease emergence in primatesAmy B Pedersen
Centre for Immunity, Infection and Evolution, Institutes of Evolutionary Biology, Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Ashworth Labs, Edinburgh EH93JT, UK
Ecohealth 6:496-508. 2009..These areas also are likely to sustain a novel epidemic due to their rapidly growing human populations, close proximity to apes, and population centers with high density and contact rates among individuals...
- Neutralizing antibodies to human and simian adenoviruses in humans and New-World monkeysJonatan Ersching
Departamento de Microbiologia, Imunologia e Parasitologia, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, 88040 900, Florianopolis, SC, Brazil
Virology 407:1-6. 2010..Surprisingly, sera from some New-World monkey species were able to neutralize AdC6 and/or AdC68. A possible explanation for these findings and the implications for the development of Ad-vector vaccines are discussed in detail...
- Widely varying SIV prevalence rates in naturally infected primate species from CameroonAvelin F Aghokeng
Laboratoire Retrovirus, UMR145, IRD, Institute for Research and Development, Montpellier, France
Virology 345:174-89. 2006..The newly developed assays should now permit to define with greater accuracy existing SIV reservoirs and associated human zoonotic risk...
- Definition of genetic markers in nuclear ribosomal DNA for a neglected parasite of primates, Ternidens deminutus (Nematoda: Strongylida)--diagnostic and epidemiological implicationsA R Schindler
Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, Victoria 3030, Australia
Parasitology 131:539-46. 2005..The genetic markers in the ITS-2 provide a foundation for improved, PCR-based diagnosis of T. deminutus infections and for investigating the life-cycle, transmission patterns and ecology of this parasite...
- Simian immunodeficiency viruses (SIVs) in AfricaAvelin F Aghokeng
Laboratoire Retrovirus, Montpellier, France
J Neurovirol 11:27-32. 2005
- Occurrence and frequency of transmission of naturally occurring simian retroviral infections (SIV, STLV, and SRV) at the CIRMF Primate Center, GabonM C Georges Courbot
, Franceville, Gabon
J Med Primatol 25:313-26. 1996..SIV infection was also more frequent in male than female mandrills and sexual transmission appeared to be a rare event. No SRV infection was observed in macaques...
- [Multiple Ebola virus haemorrhagic fever outbreaks in Gabon, from October 2001 to April 2002]D Nkoghe
Ministere de la Sante Publique, Libreville, Gabon
Bull Soc Pathol Exot 98:224-9. 2005..Unexplained deaths of animals had been mentionned in the nearby forests as soon as August 2001: great primates and cephalophus. Samples taken from their carcasses confirmed a concomitant animal epidemic...
- Other animal prion diseasesChristina J Sigurdson
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA
Br Med Bull 66:199-212. 2003..Here we review the epidemiology, transmission, clinical features and pathology of these other animal prion diseases...
- Nonhuman primate dentistryRobert B Wiggs
Coit Road Animal Hospital, 12600 Coit Road, Dallas, TX 75251
Vet Clin North Am Exot Anim Pract 6:661-87, vii. 2003..Unfortunately, alacrity generally comes from repetitive performance of procedures and entails a learning curve...
- [Uncommon mycobacterial infections in domestic and zoo animals: four cases with special emphasis on pathology]K Steiger
Institut für Veterinär Pathologie, Veterinärmedizinische Fakultät, Universitat Leipzig, An den Tierkliniken 33, 04103, Leipzig
Dtsch Tierarztl Wochenschr 110:382-8. 2003....
- A histologic demonstration of siliceous materials in simian lung mite infected lung tissues by microincinerationJames C S Kim
College of Veterinary Medicine, Chungnam National University, 200 Gungdong, Yusong gu, Daejeon 305 764, Korea
J Vet Sci 4:117-23. 2003..Therefore, until the link between lung mite infection and silicosis is clarified, experimental inhalation toxicologic findings in mite-infected Old World monkeys should be interpreted cautiously...
- The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primatesByeongwoon Song
Dana Farber Cancer Institute, 44 Binney Street, JFB 824, Boston, MA 02115, USA
J Virol 79:6111-21. 2005..The results are consistent with a role for TRIM5alpha in innate immunity against retroviruses...
- Exposure to nonhuman primates in rural CameroonNathan D Wolfe
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Emerg Infect Dis 10:2094-9. 2004..The study demonstrates that exposure is not limited to small groups of hunters. A high percentage of rural villagers report exposure to nonhuman primate blood and body fluids and risk acquiring infectious diseases...
- 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned model of parkinson's disease, with emphasis on mice and nonhuman primatesMichael W Jakowec
The George and MaryLou Boone Parkinson s Disease and Movement Disorders Research Center Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Comp Med 54:497-513. 2004..In addition, the technical use and safe handling of MPTP are discussed...
- West Nile virus infection in nonhuman primate breeding colony, concurrent with human epidemic, southern LouisianaMarion S Ratterree
Tulane National Primate Research Center, Covington, Louisiana, USA
Emerg Infect Dis 9:1388-94. 2003..The high infection rate in this captive nonhuman primate population illustrates the intensity of WNV transmission that can occur silently in nature among other susceptible vertebrates during epidemic periods...
- Stable infection of primates with Trypanosoma cruzi I and IIC V Lisboa
Department of Protozoology, Laboratory of Biology of Tripanosomatid, Institute Oswaldo Cruz IOC FIOCRUZ, Av Brasil 4365, Zip Code 21040 900, Rio de Janeiro, Brazil
Parasitology 133:603-11. 2006..Considering the high seroprevalence and stability of T. cruzi infection among the primates, these animals play an important role in the maintenance of the parasite in nature...
- PrimaTB STAT-PAK assay, a novel, rapid lateral-flow test for tuberculosis in nonhuman primatesKonstantin P Lyashchenko
Chembio Diagnostic Systems, Inc, 3661 Horseblock Road, Medford, NY 11763, USA
Clin Vaccine Immunol 14:1158-64. 2007..The highest rate of TB detection was achieved when the skin test was combined with the PrimaTB STAT-PAK kit. This novel immunoassay provides a simple, rapid, and accurate test for TB in NHP...
- Discovery of herpesviruses in multi-infected primates using locked nucleic acids (LNA) and a bigenic PCR approachSandra Prepens
P14 Molekulare Genetik und Epidemiologie von Herpesviren, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
Virol J 4:84. 2007..To illustrate this principle, six novel herpesviruses of the genera Rhadinovirus, Lymphocryptovirus and Cytomegalovirus were discovered in multi-infected samples of non-human primates and phylogenetically characterized...
- Wild primate populations in emerging infectious disease research: the missing link?N D Wolfe
Harvard School of Public Health, Boston, Massachusetts, USA
Emerg Infect Dis 4:149-58. 1998....
- Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primatePatricia L Earl
Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 33, Room 1E19, 33 North Drive, MSC 3210, Bethesda, MD 20892, USA
Virology 366:84-97. 2007..These non-human primate studies support the clinical testing of recombinant MVA as an HIV vaccine and further demonstrate that MVA can provide long-term poxvirus immunity, essential for use as an alternative smallpox vaccine...
- [The adventure of human immunodeficiency virus: from where to where?]Gülşen Ozkaya
Hacettepe Universitesi Tip Fakultesi, iç Hastaliklanri Anabilim Dali, Infeksiyon Unitesi, Ankara
Mikrobiyol Bul 40:435-43. 2006..In this review article, it has been tried to give up to date and scientific answers to these kinds of questions...
- Severe wear and tooth loss in wild ring-tailed lemurs (Lemur catta): a function of feeding ecology, dental structure, and individual life historyFrank P Cuozzo
Department of Anthropology, University of North Dakota, Box 8374, Grand Forks, ND 58202 8374, USA
J Hum Evol 51:490-505. 2006..The relationship between tooth loss, feeding ecology, dental structure, and individual life history in this population has implications for interpreting behavior based on tooth loss in the hominid fossil record...
- Association of Primate Veterinarians 34th annual workshop. ForewordD Rick Lee
Alamogordo Primate Facility
J Med Primatol 37:4. 2008
- [Evolution and virulence of primate lentiviruses]Valerie Courgnaud
Laboratoire des rétrovirus UR 36, 911, Avenue Agropolis, BP 64501, 34034 Montpellier Cedex 5, France
Med Sci (Paris) 20:448-52. 2004..Such a relationship is as a consequence of host/virus adaptation which has evolved over long periods in naturally infected primate species...
- Phylogeny of primate T lymphotropic virus type 1 (PTLV-1) including various new Asian and African non-human primate strainsSonia Van Dooren
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B 3000 Leuven, Belgium
Infect Genet Evol 7:374-81. 2007..Barbary macaques, not yet described to be STLV-infected, carry a relatively recent acquired, typical African STLV-1, giving us no clue on the phylogeographical origin of PTLV-1...
- The infrequency of transmission of herpesviruses between humans and animals; postulation of an unrecognised protective host mechanismG R Skinner
Vaccine Research Trust, Vaccine Research Institute, Moseley, Birmingham, UK
Comp Immunol Microbiol Infect Dis 24:255-69. 2001....
- Somatic variation in living, wild ring-tailed lemurs (Lemur catta)Michelle L Sauther
Department of Anthropology, University of Colorado, Boulder, CO 80309, USA
Folia Primatol (Basel) 79:55-78. 2008..Amassing such data is a critical first step to assess if wild primate populations are exhibiting normal variability or are being affected by potential inbreeding and/or environmental effects...
- Prevalence of antibody reaction with cercopithecine herpesvirus 1 antigen in Macaca cyclopis, Macaca fascicularis, and Papio anubis in TaiwanF Lee
Animal Health Research Institute, Tamsui, Taipei County, Taiwan
J Med Primatol 36:343-7. 2007....
- Use of desferoxamine and S-adenosylmethionine to treat hemochromatosis in a red ruffed lemur (Varecia variegata ruber)Carlos R Sanchez
Smithsonian National Zoological Park, 3001 Connecticut Avenue, North West, Washington, DC 20008 2598, USA
Comp Med 54:100-3. 2004..Treatment was temporarily discontinued from days 56 to 65, and the lemur's condition worsened, so therapy was re-instituted. However, the lemur died of hepatocellular carcinoma on day 110 of treatment...
- Retrospective evaluation of the incidence and severity of hemosiderosis in a large captive lemur populationKelly M Glenn
Duke University Primate Center, Durham, North Carolina, USA
Am J Primatol 68:369-81. 2006..Hemochromatosis was not observed, and excess iron was not related to the cause of death in any of the animals studied. The current findings suggest that iron overload in lemurs may be more complex than was previously believed...
- Trypanosoma cruzi prevalence and epidemiologic trends in lemurs on St. Catherines Island, GeorgiaChris A Hall
Department of Biology, Berry College, Mount Berry, Georgia 30149, USA
J Parasitol 93:93-6. 2007..cruzi on the island. This also represents the first report of autochthonous infection in blue-eyed black and black-and-white ruffed lemurs...
- DNA vaccination of infants in the presence of maternal antibody: a measles model in the primateMary Premenko-Lanier
California National Primate Research Center and Department of Pathology, School of Medicine, University of California Davis, County Road 98, Davis, CA 95616 8542, USA
Virology 307:67-75. 2003..Further, the addition of a molecular IL-2 adjuvant augments this DNA vaccine...
- The rhesus macaque as an animal model for pelvic organ prolapseLesley N Otto
Division of Urogynecology and Reproductive Pelvic Surgery, Department of Obstetrics and Gynecology, Oregon Health Science University, Portland 97201, USA
Am J Obstet Gynecol 186:416-21. 2002....
- Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADCKrystof S Bankiewicz
Department of Neurosurgery, University of California at San Francisco, Room MCB 226, 1855 Folsom Street, San Francisco, CA 94103 0555, USA
Mol Ther 14:564-70. 2006..Introduction of this therapy into the clinic holds promise for Parkinson patients experiencing the motor complications that result from escalating l-Dopa requirements against a background of disease progression...
- Typing of intimin (eae) genes in attaching and effacing Escherichia coli strains from monkeysMiguel Blanco
J Clin Microbiol 42:1382-3. 2004
- Zoonotic schistosomiasis in non-human primates: past, present and future activities at the human-wildlife interface in AfricaC J Standley
Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
J Helminthol 86:131-40. 2012..Emphasis is on the more common forms of human schistosomiasis, their clinical manifestations and epidemiological significance in terms of infection reservoir potential...
- Ape Plasmodium parasites as a source of human outbreaksL Duval
Maladies Infectieuses et Vecteurs, Ecologie, Genetique, Evolution et Contrôle, Institut de Recherche pour le Developpement, Montpellier, France
Clin Microbiol Infect 18:528-32. 2012..We review the different points of view proposed on the origin of human malaria, and discuss ape Plasmodium parasites as a source of human outbreaks...
- New STLV-3 strains and a divergent SIVmus strain identified in non-human primate bushmeat in GabonFlorian Liegeois
UMI 233, Trans VIH MI, Recherches Translationnelles sur le VIH et les Maladies Infectieuses Institut de Recherche pour le Développement IRD, University of Montpellier 1, Montpellier, France
Retrovirology 9:28. 2012..We conducted a pilot study on 63 blood and/or tissues samples derived from NHP bushmeat seized by the competent authorities in different locations across the country...
- Emerging and reemerging of filovirusesH Feldmann
Institute of Virology, Philipps University, Marburg, Federal Republic of Germany
Arch Virol Suppl 11:77-100. 1996..Factors that may be involved in emergence are international commerce and travel, limited experience in diagnosis and case management, import of nonhuman primates, and the potential of filoviruses for rapid evolution...
- Distribution of the entodiniomorphid ciliate Troglocorys cava Tokiwa, Modrý, Ito, Pomajbíková, Petrželková, & Imai, , (Entodiniomorphida: Blepharocorythidae) in wild and captive chimpanzeesKateřina Pomajbíková
Department of Pathology and Parasitology, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences, Palackeho 1 3, 612 42, Brno, Czech Republic
J Eukaryot Microbiol 59:97-9. 2012..However, the ciliate was absent in all captive groups. Prevalence appeared to increase with the number of sequential samples taken from a particular individual and reached 95.5% in wild individuals sampled at least 4 times...
- Multilocus genotyping of Giardia duodenalis reveals striking differences between assemblages A and BS M Cacció
Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
Int J Parasitol 38:1523-31. 2008..These findings raise concerns about the interpretation of genotyping data based on single markers, and indicate the need to understand the mechanisms that are responsible for the differences between G. duodenalis assemblages A and B...
- Malaria outside the Amazon region: natural Plasmodium infection in anophelines collected near an indigenous village in the Vale do Rio Branco, Itanhaém, SP, BrazilAmanda Neves
Laboratory of Protozoology, Institute of Tropical Medicine of São Paulo, University of Sao Paulo, Av Dr Enéias de Carvalho Aguiar 470, 05403 000 Sao Paulo, Brazil
Acta Trop 125:102-6. 2013..vivax and P. malariae...
- Investigation of tularemia outbreak after natural infection of outdoor-housed rhesus macaques (Macaca mulatta) with Francisella tularensisRebecca L Sammak
California National Primate Research Center, University of California, Davis, California, USA
Comp Med 63:183-90. 2013..The concurrent widespread seropositivity (53%) and low incidence of clinical disease (2.7%) in 2010 suggests that this strain of Francisella has low pathogenicity in macaques...
- Inflammatory arthritis in PongoB M Rothschild
Arthritis Center of Northeast Ohio, Youngstown 44512, USA
J Med Primatol 25:414-8. 1996..Character, distribution, and radiologic appearance revealed a picture distinguishable from spondyloarthropathy in other primates...
- Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta)Rebecca S Blackwood
California National Primate Research Center, University of California, Davis, CA, USA
Comp Med 58:81-7. 2008..In conclusion, tylosin significantly improved the fecal consistency score, significantly decreased colonic inflammation, and significantly decreased serum CRP levels post-treatment in rhesus macaques with chronic diarrhea...
- Evolution and immunology. The economics of immunityA F Read
Institute for Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, UK
Science 290:1104-5. 2000....
- Development of therapeutic and prophylactic vaccine against Tuberculosis using monkey and transgenic mice modelsYoko Kita
Clinical Research Center, National Hospital Organization Kinki chuo Chest Medical Center, Kitaku, Sakai, Osaka, Japan
Hum Vaccin 7:108-14. 2011..Therefore, novel TB vaccines were established by using three kinds of animal models (cynomolgus monkey model which is the best animal model of human TB, IL-2R knock out SCID mice as a human immune model, and granulysin transgenic mouse)...
- Microtubule- and dynein-dependent nuclear trafficking of rhesus rhadinovirus in rhesus fibroblastsWei Zhang
Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
J Virol 86:599-604. 2012..These results highlight the important roles of microtubules and dynein-dynactin complexes in the transport of RRV particles to nuclei during primary infection...
- Ocular oxyspirurosis of primates in zoos: intermediate host, worm morphology, and probable origin of the infection in the Moscow zooE Ivanova
Centre of Parasitology of A N Severtsov Institute of Ecology and Evolution, Leninskii pr, 33, 119071 Moscow, Russia
Parasite 14:287-98. 2007..Consequently the notion of type hosts is artificial and the three agents of oxyspirurosis are provisionally placed in the taxon O. (O.) conjunctivalis...
- Giardia duodenalis assemblages and Entamoeba species infecting non-human primates in an Italian zoological garden: zoonotic potential and management traitsFederica Berrilli
Dipartimento di Sanita Pubblica e Biologia Cellulare, Universita di Roma Torvergata, Rome, Italy
Parasit Vectors 4:199. 2011..In this study we carried out the molecular identification of G. duodenalis and Entamoeba spp. from nine species of primates housed in the zoological garden of Rome, to better ascertain their occurrence and zoonotic potential...
- Primates and primatologists: social contexts for interspecies pathogen transmissionG A Engel
Swedish Cherry Hill Family Medicine, Seattle, Washington 98195, USA
Am J Primatol 74:543-50. 2012....
- The effects of a single cervical inoculation of Chlamydia trachomatis on the female reproductive tract of the baboon (Papio anubis)Jason D Bell
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109, USA
J Infect Dis 204:1305-12. 2011..We sought to determine if the baboon could become infected with a single cervical inoculation of Chlamydia trachomatis...
- Morphological variability within Oesophagostomum bifurcum among different primate species from GhanaJ M de Gruijter
Department of Parasitology, Leiden University Medical Centre, University of Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands
J Helminthol 80:357-61. 2006..These findings suggest that O. bifurcum from different species of primate host represent distinct population variants, also supported by recent epidemiological and genetic studies of O. bifurcum from such hosts...
- A novel small animal model to study the replication of simian foamy virus in vivoRico Blochmann
FG18 HIV and Other Retroviruses, Robert Koch Institute, Berlin, Germany
Virology 448:65-73. 2014..The results strongly indicate establishment of a persistent infection in hamsters. These studies provide a further small animal model for studying FV-based vectors in addition to the established models...
- Extended safety and efficacy studies of a live attenuated double leucine and pantothenate auxotroph of Mycobacterium tuberculosis as a vaccine candidateSamantha L Sampson
Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
Vaccine 29:4839-47. 2011..The results support the further development of the ΔleuD ΔpanCD strain as a viable tuberculosis (TB) vaccine candidate...
- Antibody responses to a spore carbohydrate antigen as a marker of nonfatal inhalation anthrax in rhesus macaquesElke Saile
Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Division of Bacterial Diseases, Atlanta, Georgia 30333, USA
Clin Vaccine Immunol 18:743-8. 2011..These data suggest that anti-ATS antibody responses may be used to identify aerosol exposure to B. anthracis spores. The anti-ATS antibody responses were detectable during administration of ciprofloxacin...
- Parasitic zoonoses at the rodent-captive primate-human health interfaceHany M Elsheikha
School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, United Kingdom
J Egypt Soc Parasitol 39:447-60. 2009..Finally, priorities for future research are identified, including identifying those parasites for which multi-host interaction is likely to have the greatest impact...
- Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testingS A Sharpe
Health Protection Agency, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, United Kingdom
Clin Vaccine Immunol 17:1170-82. 2010..Therefore, the currently proposed key markers were not shown to correlate with protection, and only imaging offered a potentially reliable correlate...
- Molecular identification of Entamoeba spp. in captive nonhuman primatesB Levecke
Laboratory of Parasitology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
J Clin Microbiol 48:2988-90. 2010..The results revealed the presence of Entamoeba histolytica (NHP variant only), E. dispar, E. moshkovskii, E. hartmanni, E. coli, and E. polecki-like organisms...
- Gastrointestinal protozoa in non-human primates of four zoological gardens in BelgiumBruno Levecke
Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
Vet Parasitol 148:236-46. 2007..p<0.001) and C. mesnili (p<0.05). Samples containing Entamoeba spp. were the most prevalent in OW monkeys (p<0.0083). Samples collected from OW monkeys contained the highest number of parasite species (p<0.0083)...
- Molecular analysis of a novel simian virus 40 (SV40) type in rhesus macaques and evidence for double infections with the classical SV40 typeZahra Fagrouch
Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, Netherlands
J Clin Microbiol 49:1280-6. 2011..We provide evidence here for the existence of a novel SV40 type in rhesus macaques and show that double infections with both types frequently occur...
- Detection of virus-like particles in the liver of black and white ruffed lemurs with hepatitisMichael B Worley
Virology and Immunology Laboratory, Zoological Society of San Diego, P O Box 120551, San Diego, California 92112, USA
J Wildl Dis 38:258-65. 2002..The size, morphology, and density of these particles suggest they are members of the Hepadnaviridae, a group of hepatotropic DNA-genome viruses for which HBV is the prototype...
- Co-infection and cross-species transmission of divergent Hepatocystis lineages in a wild African primate communityMary I Thurber
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
Int J Parasitol 43:613-9. 2013..Hepatocystis parasites in this primate community are a diverse assemblage of cryptic lineages, some of which co-infect hosts and at least one of which can cross primate species barriers...
- Primates as pets in Mexico City: an assessment of the species involved, source of origin, and general aspects of treatmentAlejandra Duarte-Quiroga
Escuela Nacional de Antropologia e Historia, Conaculta, Mexico
Am J Primatol 61:53-60. 2003..The demand by city dwellers for primate pets, along with habitat destruction and fragmentation, exerts a significant pressure on wild populations in southern Mexico...
- Parastrongylus cantonensis in a nonhuman primate, FloridaMichael S Duffy
Cornell University, Ithaca, New York 14853, USA
Emerg Infect Dis 10:2207-10. 2004..This parasite is neurotropic and causes disease and death in humans and other mammals. We report the first identification of P. cantonensis as the cause of a debilitating neurologic disease in a captive primate in Florida...
- A novel hepacivirus with an unusually long and intrinsically disordered NS5A protein in a wild Old World primateMichael Lauck
Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin, USA
J Virol 87:8971-81. 2013..These findings shed new light on the natural history and evolution of the hepaciviruses and on the extent of structural variation within the Flaviviridae. ..
- Identification of bacterial infection in neotropical primatesAndre Menezes-Costa
Laboratório de Genética Molecular de Eucariontes e Simbiontes, Departamento de Genetica, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Ilha do Fundao, CCS, Bloco A, Lab A2 120, Rio de Janeiro, RJ, CEP 21944 970, Brazil
Microb Ecol 66:471-8. 2013..but also to Pseudomonas simiae and sheep-Acari infecting Pseudomonas spp. The identified Pseudomonas possibly represents a group of bacteria circulating in natural monkey populations...
- The genetic diversity of Plasmodium malariae and Plasmodium brasilianum from human, simian and mosquito hosts in BrazilL O Guimarães
Núcleo de Estudos em Malária, Superintendência de Controle de Endemias Instituto de Medicina Tropical de São Paulo, Universidade de Sao Paulo, Brazil
Acta Trop 124:27-32. 2012..brasilianum as has been proposed in recent studies. Taken together, our data show that based on the microsatellite data there is a relatively restricted polymorphism of P. malariae parasites as opposed to other geographic locations...
- Primate disease ecology in comparative and theoretical perspectiveCharles L Nunn
Department of Human Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Am J Primatol 74:497-509. 2012..In addition to these examples, I discuss the need for more meta-analyses of individual-level phenomena documented in the field, and for greater linkage between theoretical modeling and field research...
- Isolation of a phylogenetically distinct rabies virus from a tufted capuchin monkey (Cebus apella) in BrazilYuki Kobayashi
Nihon University Veterinary Research Center, Fujisawa, Kanagawa, Japan
Virus Res 178:535-8. 2013..This result suggests that the source of rabies infection in the tufted capuchin monkey may have been bat, and that they have a risk to act as rabies reservoir in Brazil. ..
- Investigations on anopheline mosquitoes close to the nest sites of chimpanzees subject to malaria infection in Ugandan highlandsSabrina Krief
UMR 7206 Eco anthropologie et Ethnobiologie, Museum national d histoire naturelle, Paris, France
Malar J 11:116. 2012..The avoidance of the night-biting anopheline mosquitoes is another potential behavioural adaptation that would lead to a decrease in the number of infectious bites and consequently malaria...
- Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infectionBasel T Assaf
Center for Comparative Medicine, University of California, Davis, Davis, California, USA
J Virol 86:6354-7. 2012..The results imply that vaccinating against these early viral determinants would significantly impede long-term RhCMV infection...
- Evolutionary conservation of primate lymphocryptovirus microRNA targetsRebecca L Skalsky
Department of Molecular Genetics and Microbiology and Center for Virology, Duke University Medical Center, Durham, North Carolina, USA
J Virol 88:1617-35. 2014..Finally, we investigated the functional consequences of LMP1 targeting by individual EBV BART miRNAs and show that select viral miRNAs play a role in the previously observed modulation of NF-κB activation. ..
- A comparative study of age-related brain pathology--are neurodegenerative diseases present in nonhuman animals ?Hiroyuki Nakayama
Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1 1 1 Yayoi Bunkyo ku Tokyo 113 8657, Japan
Med Hypotheses 63:198-202. 2004..As the rate of deposition of the misfolded proteins causing the lesions might be slow, nonhuman animals normally die before the lesions appear...
- Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaquesDavid Safronetz
Laboratory of Virology, Hamilton, Montana, USA
J Virol 85:1214-23. 2011..Differences in virulence may explain more severe disease, as was seen with certain individuals infected with the emerged pandemic influenza virus. Thus, the nonhuman primate model closely mimics influenza in humans...
- Intracranial meningioma in a baboon (Papio spp.)F N Oliveira
Texas Veterinary Medical Diagnostic Laboratory, Texas A and M University, College Station, TX, USA
J Comp Pathol 145:414-8. 2011..The features of this tumour are similar to those of meningiomas in other species...
- Evaluation of replication, immunogenicity and protective efficacy of a live attenuated cold-adapted pandemic H1N1 influenza virus vaccine in non-human primatesKobporn Boonnak
Emerging Respiratory Viruses Section, Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD 20892 3203, United States
Vaccine 30:5603-10. 2012....
- Retroviral restriction and dependency factors in primates and carnivoresHind J Fadel
Department of Molecular Medicine and Division of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Vet Immunol Immunopathol 143:179-89. 2011..We review progress in this area in the context of what is known about retroviral restriction factors such as TRIM5α, TRIMCyp, APOBEC3 proteins and BST-2/Tetherin...
- Genome sequence of Aggregatibacter actinomycetemcomitans RHAA1, isolated from a rhesus macaque, an Old World primateMaribasappa Karched
Department of Oral Biology, New Jersey Dental School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
J Bacteriol 194:1275-6. 2012..Aggregatibacter actinomycetemcomitans is implicated in localized aggressive periodontitis. We report the first genome sequence of an A. actinomycetemcomitans strain isolated from an Old World primate...
- Attenuated NYCBH vaccinia virus deleted for the E3L gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaquesKaren L Denzler
Biodesign Institute, Arizona State University, Tempe, AZ 85287 5401, USA
Vaccine 29:9684-90. 2011..These results suggest that although the highly attenuated NYCBHΔE3L allows proinflammatory signal transduction to occur, it does not provide full protection against monkeypox challenge...
- Social processes and disease in nonhuman primates: introduction to the special sectionJohn P Capitanio
California National Primate Research Center, University of California, Davis, California 95616, USA
Am J Primatol 74:491-6. 2012....
- Genome-wide analysis of T cell responses during acute and latent simian varicella virus infections in rhesus macaquesKristen Haberthur
Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon, USA
J Virol 87:11751-61. 2013..Given the close genome relatedness of SVV and VZV, our studies highlight immunogenic ORFs that may be further investigated as potential components of novel VZV vaccines that specifically boost T cell immunity. ..
- Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaquesKristina Abel
California National Primate Research Center, University of California, Davis, County Rd 98 and Hutchison Dr, Davis, CA 95616 8542, USA
J Virol 85:2878-90. 2011....
- The evolution of virulence in primate malaria parasites based on Bayesian reconstructions of ancestral statesLászló Zsolt Garamszegi
Department of Evolutionary Ecology, Estacion Biologica de Donana, Consejo Superior de Investigaciones Cientificas, c Americo Vespucio, S N, 41092 Sevilla, Spain
Int J Parasitol 41:205-12. 2011..Consequently, the extreme variation in the outcome of malaria infection in different host species can be better understood in light of the phylogeny of parasites...
- [Nematodes of the genus Oesophagostomum: an emerging risk for humans and apes in Africa?]Jacques Guillot
UMR BIPAR, Service de Parasitologie, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex
Bull Acad Natl Med 195:1955-63; discussion 1963. 2011..In Uganda, where the situation is diferent, cross-infection is probably more frequent...
- Development of an inhalational Bacillus anthracis exposure therapeutic model in cynomolgus macaquesLisa N Henning
Battelle, Columbus, Ohio, USA
Clin Vaccine Immunol 19:1765-75. 2012..Our results support the use of the cynomolgus macaque as an appropriate therapeutic animal model for assessing the efficacy of medical countermeasures developed against anthrax when administered after a confirmation of infection...
- Dating the origin and dispersal of hepatitis B virus infection in humans and primatesDimitrios Paraskevis
Department of Hygiene, Epidemiology and Medical Statistics, Medical School, University of Athens, Athens, Greece
Hepatology 57:908-16. 2013..We also show that the non-human HBV clades in orangutans and gibbons resulted from cross-species transmission events from humans that occurred no earlier than 6,100 years ago...
- Development of whole-virus multiplex luminex-based serological assays for diagnosis of infections with kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 homologs in macaquesJonathan T Ryan
Center for Childhood Infections and Prematurity Research, Seattle Children s Research Institute, Seattle, WA, USA
Clin Vaccine Immunol 20:409-19. 2013..This will help advance our understanding of rhadinovirus biology and associated host immunological responses...
- The frequency of CD127(+) hepatitis C virus (HCV)-specific T cells but not the expression of exhaustion markers predicts the outcome of acute HCV infectionEui Cheol Shin
Immunology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, DHHS, Bethesda, Maryland, USA
J Virol 87:4772-7. 2013....
- Protozoan parasites in group-living primates: testing the biological island hypothesisColin A Chapman
Department of Anthropology and McGill School of Environment, McGill University, Montreal, Quebec, Canada
Am J Primatol 74:510-7. 2012..Whatever the ultimate explanation for these changes, our findings have implications for studies proposing selective forces shaping primate behavior and social organization...
- Adenoviruses isolated from wild gorillas are closely related to human species C virusesMcVey Duncan
GenVec, Inc, 65W Watkins Mill Rd, Gaithersburg, MD 20878, USA
Virology 444:119-23. 2013..The human adenovirus 5 fiber knob blocked infection, suggesting use of the Coxsackie and Adenovirus Receptor. These viruses may provide viral vectors with properties distinct from chimpanzee adenovirus and human adenovirus vectors. ..
- Simian varicella virus gene 61 encodes a viral transactivator but is non-essential for in vitro replicationW L Gray
Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Arch Virol 152:553-63. 2007..SVV gene 61 is expressed in liver, lung, and neural ganglia of infected monkeys during acute simian varicella...
- Virus infection stages and distinct Th1 or Th17/Th22 T-cell responses in malaria/SHIV coinfection correlate with different outcomes of diseaseBridgett Ryan-Payseur
Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago 60612, USA
J Infect Dis 204:1450-62. 2011..It remains unknown whether distinct immune responses during coinfection with malaria and human immunodeficiency virus (HIV) affect clinical outcomes...
- A re-evaluation of M. prototuberculosisNoel H Smith
PLoS Pathog 2:e98. 2006
- Efficacy of a Novel Neuroprotective Compound in Nonhuman PrimateAndrew A Pieper; Fiscal Year: 2013..we can begin to explore the therapeutic potential of the P7C3 class of molecules in sophisticated nonhuman primate diseases models, we must first establish a neuroprotective role for the P7C3 class of molecules in the primate brain...
- Trafficking, persistence and evolution of HIV in the CNSPeter Simmonds; Fiscal Year: 2005....
- Pathogenesis of New SIVsm Lineages in Rhesus MacaquesCristian Apetrei; Fiscal Year: 2009..By providing an array of SIVsm strains showing roughly the same degree of divergence as HIV-1 group M subtypes, our model may be used for the study of heterotypic protection. ..
- MOLECULAR EVOLUTION OF P. FALCIPARUM AND P VIVAXAnanias Escalante; Fiscal Year: 2003....
- Methamphetamine, Stress and SIV: Effects at Blood-Brain Barrier and Lymph NodesJohn P Capitanio; Fiscal Year: 2010..Relevance ..
- Animal Model for SIV Infection ControlIvona Pandrea; Fiscal Year: 2010..Deciphering the mechanisms of viral control in this new model may significantly contribute to our understanding of HIV pathogenesis and design of new approaches for controlling HIV infection. ..
- SIMIAN AIDS: SOCIAL STRESS, ENDOCRINE & IMMUNE FUNCTIONJohn Capitanio; Fiscal Year: 2004..abstract_text> ..
- SOY, LIFE STAGE, STRESS AND ATHEROSCLEROSIS IN FEMALESJAY KAPLAN; Fiscal Year: 2009....
- MODELING THE MENOPAUSAL TRANSITION AND MENOPAUSEJAY KAPLAN; Fiscal Year: 2008..Therefore the proposed program is directly relevant to the missions of multiple NIHInstitutes, including - butnot limited to - NIA, NICHD, NHLBI, NIDDKand NIMH. ..
- Prophylactic and Therapeutic Immunization against H. pylori in Rhesus MacaquesJAY SOLNICK; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Host specific responses in SIV-induced hematosuppressionGuido Silvestri; Fiscal Year: 2007..Understanding HIV-induced BM suppression will be key for effective hematologic and immune reconstitution strategies. ..
- Gene expression during H. pylori-host interactionsJAY SOLNICK; Fiscal Year: 2007..These studies will provide a functional genomic understanding of the H. pylori host-pathogen relationship that may have implications for novel treatment or vaccine strategies. ..
- Animal models to design & evaluate improved VZV vaccinesWAYNE GRAY; Fiscal Year: 2007..The study may also provide support for use of the VZV vaccine as a recombinant vector for immunization against other infectious agents, particularly human immunodeficiency virus (HIV). ..
- Primate enteroviruses transmission in BangladeshLisa Jones Engel; Fiscal Year: 2007..Ultimately, this data will provide insight into the potential emergence of NHP-borne pathogens and help to deter the spread of emerging zoonotic threats. [unreadable] [unreadable]..
- Studies of the HIV-associated cell cycle diseaseGuido Silvestri; Fiscal Year: 2006..unreadable] [unreadable]..
- Transmission of H. pylori infection in the rhesus monkeyJAY SOLNICK; Fiscal Year: 2005..pylori; 3) Determine the effects of H. pylori infection on the acquisition of Campylobacter jejuni; and 4) Determine the effects of the CagA pathogenicity island on colonization and shedding. ..
- Transcription of H. pylori Genes in the Rhesus MonkeyJAY SOLNICK; Fiscal Year: 2002..An understanding of the dynamic interaction between host and pathogen may point the way toward critical proteins that may be useful as targets for therapy or vaccine development. ..