dog diseases

Summary

Summary: Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.

Top Publications

  1. ncbi Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis
    L Solano-Gallego
    Dept Pathology and Infectious Diseases, Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Herts, UK
    Vet Parasitol 165:1-18. 2009
  2. pmc Vector-borne helminths of dogs and humans in Europe
    Domenico Otranto
    Dipartimento di Medicina Veterinaria, Universita degli Studi di Bari, Bari, Valenzano, Italy
    Parasit Vectors 6:16. 2013
  3. ncbi Genome sequence, comparative analysis and haplotype structure of the domestic dog
    Kerstin Lindblad-Toh
    Broad Institute of Harvard and MIT, 320 Charles Street, Cambridge, Massachusetts 02141, USA
    Nature 438:803-19. 2005
  4. pmc Control of visceral leishmaniasis in latin america-a systematic review
    Gustavo A S Romero
    Nucleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasilia, Brasilia, Distrito Federal, Brazil
    PLoS Negl Trop Dis 4:e584. 2010
  5. ncbi Babesiosis in dogs and cats--expanding parasitological and clinical spectra
    Laia Solano-Gallego
    Department of Pathology and Infectious Diseases, Royal Veterinary College of London, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK
    Vet Parasitol 181:48-60. 2011
  6. ncbi Canine leishmaniosis in the Old and New Worlds: unveiled similarities and differences
    Filipe Dantas-Torres
    Department of Immunology, Aggeu Magalhães Research Institute, Oswaldo Cruz Foundation, 50670 420 Recife, Pernambuco, Brazil
    Trends Parasitol 28:531-8. 2012
  7. pmc LeishVet guidelines for the practical management of canine leishmaniosis
    Laia Solano-Gallego
    Department of Pathology and Infectious Diseases, Royal Veterinary College of London, London, UK
    Parasit Vectors 4:86. 2011
  8. ncbi Emerging arthropod-borne diseases of companion animals in Europe
    Frederic Beugnet
    Meria Animal Health, 69007, Lyon, France
    Vet Parasitol 163:298-305. 2009
  9. ncbi Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis
    R J Quinnell
    Institute of Integrative and Comparative Biology, University of Leeds, Leeds LS2 9JT, UK
    Parasitology 136:1915-34. 2009
  10. pmc The synergistic action of imidacloprid and flumethrin and their release kinetics from collars applied for ectoparasite control in dogs and cats
    Dorothee Stanneck
    Bayer Animal Health GmbH, Leverkusen, Germany
    Parasit Vectors 5:73. 2012

Research Grants

Detail Information

Publications314 found, 100 shown here

  1. ncbi Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis
    L Solano-Gallego
    Dept Pathology and Infectious Diseases, Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Herts, UK
    Vet Parasitol 165:1-18. 2009
    ..Protection against sand fly bites by topical insecticides is effective in reducing infection, and recent development of vaccines has indicated that prevention by vaccination is feasible...
  2. pmc Vector-borne helminths of dogs and humans in Europe
    Domenico Otranto
    Dipartimento di Medicina Veterinaria, Universita degli Studi di Bari, Bari, Valenzano, Italy
    Parasit Vectors 6:16. 2013
    ..In addition, this article provides the authors' opinion on some topics related to VBH that would deserve further scientific investigation...
  3. ncbi Genome sequence, comparative analysis and haplotype structure of the domestic dog
    Kerstin Lindblad-Toh
    Broad Institute of Harvard and MIT, 320 Charles Street, Cambridge, Massachusetts 02141, USA
    Nature 438:803-19. 2005
    ..The current SNP map now makes it possible for genome-wide association studies to identify genes responsible for diseases and traits, with important consequences for human and companion animal health...
  4. pmc Control of visceral leishmaniasis in latin america-a systematic review
    Gustavo A S Romero
    Nucleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasilia, Brasilia, Distrito Federal, Brazil
    PLoS Negl Trop Dis 4:e584. 2010
    ....
  5. ncbi Babesiosis in dogs and cats--expanding parasitological and clinical spectra
    Laia Solano-Gallego
    Department of Pathology and Infectious Diseases, Royal Veterinary College of London, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK
    Vet Parasitol 181:48-60. 2011
    ..Accurate detection and species recognition are important for the selection of the correct therapy and prediction of the course of disease...
  6. ncbi Canine leishmaniosis in the Old and New Worlds: unveiled similarities and differences
    Filipe Dantas-Torres
    Department of Immunology, Aggeu Magalhães Research Institute, Oswaldo Cruz Foundation, 50670 420 Recife, Pernambuco, Brazil
    Trends Parasitol 28:531-8. 2012
    ..Finally, it calls the attention of veterinary and public health authorities to standardize and improve practices for diagnosing, treating, and preventing the disease...
  7. pmc LeishVet guidelines for the practical management of canine leishmaniosis
    Laia Solano-Gallego
    Department of Pathology and Infectious Diseases, Royal Veterinary College of London, London, UK
    Parasit Vectors 4:86. 2011
    ....
  8. ncbi Emerging arthropod-borne diseases of companion animals in Europe
    Frederic Beugnet
    Meria Animal Health, 69007, Lyon, France
    Vet Parasitol 163:298-305. 2009
    ..Here, after consideration of the main reasons for changes in tick vector ecology, an overview of each "emerging" vector-borne diseases of pets is presented...
  9. ncbi Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis
    R J Quinnell
    Institute of Integrative and Comparative Biology, University of Leeds, Leeds LS2 9JT, UK
    Parasitology 136:1915-34. 2009
    ..Topical insecticides (deltamethrin-impregnated collars and pour-ons) have been shown to provide a high level of individual protection to treated dogs, but further community-level studies are needed...
  10. pmc The synergistic action of imidacloprid and flumethrin and their release kinetics from collars applied for ectoparasite control in dogs and cats
    Dorothee Stanneck
    Bayer Animal Health GmbH, Leverkusen, Germany
    Parasit Vectors 5:73. 2012
    ..A new polymer matrix collar has recently been developed which is registered for 8 months use in cats and dogs. The basic properties of this collar have been investigated in several in vitro and in vivo studies...
  11. ncbi Canine leishmaniosis - new concepts and insights on an expanding zoonosis: part one
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, PO Box 12, Rehovot, Israel
    Trends Parasitol 24:324-30. 2008
    ....
  12. ncbi Evidence for evolution of canine parvovirus type 2 in Italy
    C Buonavoglia
    Department of Animal Health and Well Being, Faculty of Veterinary Medicine of Bari, s p per Casamassima km 3, 70010 Valenzano, Bari, Italy
    J Gen Virol 82:3021-5. 2001
    ..The failure of established typing methods to distinguish this antigenic variant was overcome by the development of an RFLP assay...
  13. ncbi A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis
    Claude Favrot
    Clinical for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Vet Dermatol 21:23-31. 2010
    ..It is finally demonstrated that these new sets of criteria provide better sensitivity and specificity, when compared to Willemse and Prélaud criteria. These criteria can be applied to both FIAD and NFIAD dogs...
  14. ncbi Heartworm disease in animals and humans
    John W McCall
    Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA
    Adv Parasitol 66:193-285. 2008
    ..repens in humans in Europe. The chapter concludes with a discussion on emerging strategies in heartworm treatment and control, highlighting the potential role of tetracycline antibiotics in adulticidal therapy...
  15. ncbi Role of pet dogs and cats in the transmission of helminthic zoonoses in Europe, with a focus on echinococcosis and toxocarosis
    Peter Deplazes
    Institute of Parasitology, Vetsuisse Faculty, University of Zurich, Switzerland
    Vet Parasitol 182:41-53. 2011
    ..A close collaboration between veterinary and public health professionals in a 'One Health' concept is required...
  16. ncbi An ELISA for sensitive and specific detection of circulating antigen of Angiostrongylus vasorum in serum samples of naturally and experimentally infected dogs
    M Schnyder
    Institute of Parasitology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 266a, CH 8057 Zurich, Switzerland
    Vet Parasitol 179:152-8. 2011
    ..vasorum antigen by ELISA represents a valid alternative for reliable diagnosis and for follow-up investigations after anthelmintic treatment. Moreover, the test can be used for mass screening in large epidemiological investigations...
  17. ncbi Canine leishmaniasis
    Jorge Alvar
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
    Adv Parasitol 57:1-88. 2004
    ....
  18. ncbi Evolution of clinical, haematological and biochemical findings in young dogs naturally infected by vector-borne pathogens
    Donato de Caprariis
    Dipartimento di Sanità Pubblica e Zootecnia, Universita degli Studi di Bari, Valenzano, BA, Italy
    Vet Microbiol 149:206-12. 2011
    ..vogeli or A. platys and Bartonella spp. co-infections. This study emphasizes the clinical difficulties associated with assigning a specific clinical sign or haematological abnormality to a particular canine vector-borne disease...
  19. ncbi Risk factors for canine leishmaniasis in an endemic Mediterranean region
    Sofia Cortes
    Unidade de Leishmanioses, Instituto de Higiene e Medicina Tropical, Rua da Junqueira, 100, 1346 008 Lisboa, Portugal
    Vet Parasitol 189:189-96. 2012
    ..The future of CanL prevention and control rely on an integrated approach involving veterinarians, dog owners and health authorities in order to reduce the canine infection risk and consequently, the human zoonotic visceral leishmaniasis...
  20. pmc Evaluation of the long-term efficacy and safety of an imidacloprid 10%/flumethrin 4.5% polymer matrix collar (Seresto®) in dogs and cats naturally infested with fleas and/or ticks in multicentre clinical field studies in Europe
    Dorothee Stanneck
    Bayer Animal Health GmbH BAH, Monheim, Germany
    Parasit Vectors 5:66. 2012
    ....
  21. pmc Efficacy of an imidacloprid/flumethrin collar against fleas, ticks, mites and lice on dogs
    Dorothee Stanneck
    Bayer HealthCare AG, Animal Health Division, 51368 Leverkusen, Germany
    Parasit Vectors 5:102. 2012
    ....
  22. pmc The prevalence of canine Leishmania infantum infection in western China detected by PCR and serological tests
    Jun yun Wang
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People s Republic of China
    Parasit Vectors 4:69. 2011
    ....
  23. pmc Thelazia callipaeda: infection in dogs: a new parasite for Spain
    Guadalupe Miró
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense, de Madrid, Spain
    Parasit Vectors 4:148. 2011
    ..Italy, France, Germany and Switzerland). In June 2010, the first case of canine thelaziosis was observed in central western Spain (La Vera region, Cáceres) and subsequent epidemiological investigation is reported in the present study...
  24. ncbi Application of 10% imidacloprid/50% permethrin to prevent Ehrlichia canis exposure in dogs under natural conditions
    Domenico Otranto
    Department of Veterinary Public Health, Faculty of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy
    Vet Parasitol 153:320-8. 2008
    ..canis at one or both follow-ups. ImPer, by virtue of its repellent and acaricidal activity against ticks, has been shown to be efficacious to prevent E. canis infection in treated dogs living under natural conditions in endemic areas...
  25. pmc Prevalence of Leishmania infantum infection in dogs living in an area of canine leishmaniasis endemicity using PCR on several tissues and serology
    L Solano-Gallego
    Departament de Farmacologia i Terapeutica, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Clin Microbiol 39:560-3. 2001
    ..The results showed that the majority of dogs living in an area where canine leishmaniasis is endemic are infected by Leishmania and that the prevalence of infection is much greater than the prevalence of overt Leishmania-related disease...
  26. pmc A novel unstable duplication upstream of HAS2 predisposes to a breed-defining skin phenotype and a periodic fever syndrome in Chinese Shar-Pei dogs
    Mia Olsson
    Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
    PLoS Genet 7:e1001332. 2011
    ..The identification of HA as a major risk factor for this canine disease raises the potential of this glycosaminoglycan as a risk factor for human periodic fevers and as an important driver of chronic inflammation...
  27. ncbi Infectiousness in a cohort of brazilian dogs: why culling fails to control visceral leishmaniasis in areas of high transmission
    Orin Courtenay
    Ecology and Epidemiology Group, Department of Biological Sciences, University of Warwick, Coventry, United Kingdom
    J Infect Dis 186:1314-20. 2002
    ..Mathematical modeling suggests that culling programs fail because of high incidence of infection and infectiousness, the insensitivity of the diagnostic test to detect infectious dogs, and time delays between diagnosis and culling...
  28. ncbi The role of dogs as reservoirs of Leishmania parasites, with emphasis on Leishmania (Leishmania) infantum and Leishmania (Viannia) braziliensis
    Filipe Dantas-Torres
    Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes, Fundacao Oswaldo Cruz, CP 7472, Recife 50670 420, Pernambuco, Brazil
    Vet Parasitol 149:139-46. 2007
    ..V.) braziliensis. In the present article, the role of dogs as reservoirs of Leishmania parasites, with emphasis on L. (L.) infantum and L. (V.) braziliensis, is reviewed...
  29. ncbi Detection of specific antibodies in dogs infected with Angiostrongylus vasorum
    A Schucan
    Institute of Parasitology, Vetsuisse Faculty, University of Zurich, Winterthurerstr 266a, CH 8057 Zurich, Switzerland
    Vet Parasitol 185:216-24. 2012
    ..The early detection of specific antibodies against A. vasorum by ELISA represents a valid alternative for a reliable diagnosis and for follow-up investigations after anthelmintic treatment...
  30. pmc Incidence and time course of Leishmania infantum infections examined by parasitological, serologic, and nested-PCR techniques in a cohort of naive dogs exposed to three consecutive transmission seasons
    Gaetano Oliva
    Unit of Vector borne Diseases and International Health, MIPI Department, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Clin Microbiol 44:1318-22. 2006
    ....
  31. ncbi Role of dog behaviour and environmental fecal contamination in transmission of Echinococcus multilocularis in Tibetan communities
    A Vaniscotte
    Department of Chrono Environment, UMR UFC CNRS 6249 aff INRA, University of Franche Comte, 25030 Besancon Cedex, France
    Parasitology 138:1316-29. 2011
    ..multilocularis peri-domestic cycles and to identify behavioural parameters required to model E. multilocularis transmission in this region...
  32. ncbi Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes
    Jean Loup Lemesre
    Institut de Recherche pour le Developpement, UR 008 Pathogénie des Trypanosomatidae, 911 Avenue Agropolis, BP 64501, 34394 Montpellier Cedex 5, France
    Vaccine 23:2825-40. 2005
    ..infantum-infected CM-DM were co-cultured with autologous lymphocytes. Overall, our results support the view that a LiESAp vaccine might be useful in a promising vaccination approach against natural L. infantum infection...
  33. pmc The origin and phylogeography of dog rabies virus
    Herve Bourhy
    Institut Pasteur, UPRE Lyssavirus Dynamics and Host Adaptation, World Health Organization Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, 75724 Paris Cedex 15, France
    J Gen Virol 89:2673-81. 2008
    ..Overall, our study reveals that the stochastic processes of genetic drift and population subdivision are the most important factors shaping the global phylogeography of canid RABV...
  34. pmc Vector-borne diseases--constant challenge for practicing veterinarians: recommendations from the CVBD World Forum
    Gad Baneth
    Koret School of Veterinary Medicine, The Robert H Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem Rehovot, Israel
    Parasit Vectors 5:55. 2012
    ..As a result of these discussions, we, the members of the CVBD Forum have developed the following recommendations to veterinarians for the management of CVBDs...
  35. ncbi Protective immunity against challenge with Leishmania (Leishmania) chagasi in beagle dogs vaccinated with recombinant A2 protein
    Ana Paula Fernandes
    Department of Clinical and Toxicological Analysis, School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
    Vaccine 26:5888-95. 2008
    ....
  36. pmc Response to a rabies epidemic, Bali, Indonesia, 2008-2011
    Anak Agung Gde Putra
    Disease Investigation Center, Denpasar, Bali, Indonesia
    Emerg Infect Dis 19:648-51. 2013
    ..However, the incidence of dog bites remains high, and repeat campaigns are necessary to eliminate rabies in Bali...
  37. pmc Genome-wide mRNA sequencing of a single canine cerebellar cortical degeneration case leads to the identification of a disease associated SPTBN2 mutation
    Oliver P Forman
    Kennel Club Genetics Centre, Animal Health Trust, Kentford, Newmarket, Suffolk, CB8 7UU, UK
    BMC Genet 13:55. 2012
    ..We used genome-wide mRNA sequencing (mRNA-seq) of cerebellum tissue from a single Beagle with neonatal cerebellar cortical degeneration as a method of candidate gene sequencing, with the aim of identifying the causal mutation...
  38. ncbi Incidence of and survival after mammary tumors in a population of over 80,000 insured female dogs in Sweden from 1995 to 2002
    Agneta Egenvall
    Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, SE 750 07 Uppsala, Sweden
    Prev Vet Med 69:109-27. 2005
    ..At the ages 6, 8 and 10 years, 1%, 6% and 13% respectively, of all females had at least one MT claim. The MT mortality was 6 deaths per 10,000 DYAR and increased with age. The overall-case fatality was 6%...
  39. ncbi Canine angiostrongylosis: the French heartworm: an emerging threat in North America
    G A Conboy
    Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, Canada
    Vet Parasitol 176:382-9. 2011
    ..Current treatment options include moxidectin, milbemycin oxime, and fenbendazole...
  40. ncbi Molecular biological aspects on canine and human mammary tumors
    P Rivera
    Center of Clinical Comparative Oncology C3O, Department of Clinical Sciences, Division of Small Animals, Swedish University of Agricultural Sciences, PO Box 7054, S 750 07, Uppsala, Sweden
    Vet Pathol 48:132-46. 2011
    ..The findings in larger genomewide association analyses and cDNA expression arrays are described, and the BRCA1/BRCA2 complex is compared in detail between the 2 species...
  41. ncbi Growth hormone receptor (GHR) RNAi decreases proliferation and enhances apoptosis in CMT-U27 canine mammary carcinoma cell line
    K M Pawłowski
    Faculty of Veterinary Medicine, Department of Physiological Sciences, Warsaw University of Life Sciences WULS, Warsaw, Poland
    Vet Comp Oncol 10:2-15. 2012
    ..This study indicates that GHR besides proliferative effect promotes growth by increasing cell survival. It can tilt the balance between proliferation and death in cancer cells...
  42. pmc Population genetic structure of the Staphylococcus intermedius group: insights into agr diversification and the emergence of methicillin-resistant strains
    Jeanette Bannoehr
    Laboratory for Bacterial Evolution and Pathogenesis, Centre for Infectious Diseases, The Chancellor s Building, New Royal Infirmary, University of Edinburgh, Edinburgh EH16 4SB, Scotland
    J Bacteriol 189:8685-92. 2007
    ..pseudintermedius clones found on different continents. Taken together, these data have resolved the population genetic structure of the S. intermedius group, resulting in new insights into its ancient and recent evolution...
  43. ncbi Expression of IFN-gamma, TNF-alpha, IL-10 and TGF-beta in lymph nodes associates with parasite load and clinical form of disease in dogs naturally infected with Leishmania (Leishmania) chagasi
    Cintia F Alves
    Departamento de Parasitologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Minas Gerais, Brazil
    Vet Immunol Immunopathol 128:349-58. 2009
    ..Hence, the balance of expression of IFN-gamma and TNF-alpha (protective) and IL-10 and TGF-beta (disease progression) in lymph nodes determine parasite burden and clinical expression in naturally infected dogs...
  44. ncbi Classification and grading of canine mammary tumors
    M Goldschmidt
    Laboratory of Pathology and Toxicology, University of Pennsylvania, School of Veterinary Medicine, 3900 Delancey Street, Philadelphia, PA 19104, USA
    Vet Pathol 48:117-31. 2011
    ..These have been incorporated into the proposed new classification system. This article also compares the grading systems for canine mammary carcinomas and their use for prognosis, along with the histologic classification...
  45. pmc Case report: First evidence of human zoonotic infection by Onchocerca lupi (Spirurida, Onchocercidae)
    Domenico Otranto
    Department of Veterinary Public Health, Universita degli Studi di Bari, Valenzano, Italy
    Am J Trop Med Hyg 84:55-8. 2011
    ..lupi should be considered in the differential diagnosis of other eye parasitic infections in humans. The role of dogs as natural hosts of O. lupi and the vectors of this zoonotic parasite need to be investigated...
  46. ncbi Canine and feline infections by cardiopulmonary nematodes in central and southern Italy
    Angela Di Cesare
    Department of Comparative Biomedical Sciences, Faculty of Veterinary Medicine, Teramo, Italy
    Parasitol Res 109:S87-96. 2011
    ..Larger surveys are necessary to gain more information on the diffusion of these parasites, especially for C. aerophila and A. vasorum, for which the actual distribution is poorly known...
  47. ncbi Tick-borne infections in dogs-an emerging infectious threat
    Bruno Chomel
    Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Parasitol 179:294-301. 2011
    ....
  48. ncbi The current status of zoonotic leishmaniases and approaches to disease control
    Marina Gramiccia
    Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy
    Int J Parasitol 35:1169-80. 2005
    ..Laboratory and field studies have shown improved efficacy of these preparations for both individual and mass protection...
  49. ncbi Clonal spread of methicillin-resistant Staphylococcus pseudintermedius in Europe and North America: an international multicentre study
    Vincent Perreten
    Institute of Veterinary Bacteriology, University of Berne, Berne, Switzerland
    J Antimicrob Chemother 65:1145-54. 2010
    ..The aim of this study was to determine the phenotypic and genotypic resistance profiles of methicillin-resistant Staphylococcus pseudintermedius (MRSP) and to examine the clonal distribution in Europe and North America...
  50. ncbi Canine leishmaniosis--new concepts and insights on an expanding zoonosis: part two
    Guadalupe Miró
    Departmento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain
    Trends Parasitol 24:371-7. 2008
    ..Integrated prevention with topical insecticides reducing the feeding of vectors and vaccination blocking early infection would be the basis of successful control programs...
  51. ncbi Performance of a commercially available in-clinic ELISA for the detection of antibodies against Anaplasma phagocytophilum, Ehrlichia canis, and Borrelia burgdorferi and Dirofilaria immitis antigen in dogs
    Ramaswamy Chandrashekar
    Immunoassay R and D, IDEXX Laboratories, 1 IDEXX Dr, Westbrook, ME 04092, USA
    Am J Vet Res 71:1443-50. 2010
    ..To evaluate the sensitivity and specificity of a commercially available in-clinic ELISA for detection of heartworm infection and tick-borne diseases in dogs...
  52. ncbi Managing canine vector-borne diseases of zoonotic concern: part one
    Domenico Otranto
    Department of Veterinary Public Health, University of Bari, 70010 Valenzano, Bari, Italy
    Trends Parasitol 25:157-63. 2009
    ....
  53. ncbi Advances in the pathogenesis of canine leishmaniosis: epidemiologic and diagnostic implications
    Manolis N Saridomichelakis
    Clinic of Medicine, School of Veterinary Medicine, University of Thessaly, Karditsa, Greece
    Vet Dermatol 20:471-89. 2009
    ....
  54. pmc Zoonoses in the bedroom
    Bruno B Chomel
    Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Emerg Infect Dis 17:167-72. 2011
    ..The estimated percentage of pet owners who allow dogs and cats on their beds is 14%-62%. However, public health risks, including increased emergence of zoonoses, may be associated with such practices...
  55. ncbi Canine mammary gland tumors
    Karin Sorenmo
    University of Pennsylvania, School of Veterinary Medicine, Department of Clinical Studies, 3900 Delancey Street, Philadelphia, PA 19104, USA
    Vet Clin North Am Small Anim Pract 33:573-96. 2003
    ....
  56. ncbi The veterinary and public health significance of hookworm in dogs and cats in Australia and the status of A. ceylanicum
    Carlysle S Palmer
    WHO Collaborating Centre for Molecular Epidemiology of Parasitic Infections, School of Veterinary and Biomedical Sciences and Western Australian State Agricultural Biotechnology Centre, Murdoch University, Perth, Australia
    Vet Parasitol 145:304-13. 2007
    ....
  57. ncbi PCR detection of Angiostrongylus vasorum in faecal samples of dogs and foxes
    Mohammad N S Al-Sabi
    Department of Agriculture and Ecology, Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark
    Parasitol Res 107:135-40. 2010
    ....
  58. ncbi Chemotherapy of canine leishmaniosis
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, P O Box 12, 76100, Rehovot, Israel
    Vet Parasitol 106:315-24. 2002
    ..Due to the current lack of an ultimate and effective therapy for canine leishmaniosis, new drugs, delivery systems and treatment strategies are necessary to achieve a consistent parasitological cure in infected dogs...
  59. ncbi Chronic enteropathies in dogs: evaluation of risk factors for negative outcome
    K Allenspach
    Small Animal Teaching Hospital of the University of Bern, Department of Veterinary Clinical Medicine, Vetsuisse Faculty, Switzerland
    J Vet Intern Med 21:700-8. 2007
    ....
  60. ncbi Infectivity of seropositive dogs, showing different clinical forms of leishmaniasis, to Lutzomyia longipalpis phlebotomine sand flies
    Erika Monteiro Michalsky
    Centro de Pesquisas Rene Rachou Fiocruz, Av Augusto de Lima, 1715, Barro Preto, Belo Horizonte, CEP 30190 002, MG, Brazil
    Vet Parasitol 147:67-76. 2007
    ..The lower infectivity rates of dogs displaying any of the last two clinical forms of leishmaniasis, however, must be taken into account in the epidemiology of CVL...
  61. ncbi Transmission of methicillin-resistant Staphylococcus pseudintermedius between infected dogs and cats and contact pets, humans and the environment in households and veterinary clinics
    E van Duijkeren
    Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, PO Box 80165, 3508 TD Utrecht, Netherlands
    Vet Microbiol 150:338-43. 2011
    ....
  62. ncbi Canine leishmaniasis: epidemiological risk and the experimental model
    Javier Moreno
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologi a, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo km 2, 28220 Majadahonda, Spain
    Trends Parasitol 18:399-405. 2002
    ..Such studies are essential to determine the basis of the canine protective immune response and to establish a laboratory model, a significant aspect for the development of vaccines against canine leishmaniasis...
  63. ncbi Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine
    P D Eckersall
    Division of Animal Production and Public Health, Institute of Comparative Medicine, Faculty of Veterinary Medicine, University of Glasgow, Glasgow G61 1QH, UK
    Vet J 185:23-7. 2010
    ....
  64. ncbi Advantages of real-time PCR assay for diagnosis and monitoring of canine leishmaniosis
    O Francino
    Servei Veterinari de Genètica Molecular, Facultat de Veterinaria, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Vet Parasitol 137:214-21. 2006
    ..The continuous data provided by real-time qPCR could solve the dilemma for the clinician managing cases of canine leishmaniosis by differentiating between Leishmania-infected dogs or dogs with active disease of leishmaniosis...
  65. ncbi Efficacy of a combination of 10% imidacloprid/50% permethrin for the prevention of leishmaniasis in kennelled dogs in an endemic area
    Domenico Otranto
    Department of Animal Health and Welfare, Faculty of Veterinary Medicine, University of Bari, Str Prov per Casamassima Km3, 70010 Valenzano Bari, Italy
    Vet Parasitol 144:270-8. 2007
    ..01). The results clearly show that a combination of imidacloprid 10% and permethrin 50%, by virtue of its repellent activity against sandflies, is effective under both application regimes in preventing CanL in the field in endemic areas...
  66. ncbi Humoral and cellular immune responses in dogs with inapparent natural Leishmania infantum infection
    W Coura-Vital
    Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil
    Vet J 190:e43-7. 2011
    ..Asymptomatic dogs appear to have a dichotomous infection spectrum that can influence the humoral and cellular immunological status during canine visceral leishmaniasis...
  67. pmc Human benefits of animal interventions for zoonosis control
    Jakob Zinsstag
    Swiss Tropical Institute, Basel, Switzerland
    Emerg Infect Dis 13:527-31. 2007
    ....
  68. ncbi Morphological and molecular data on the dermal microfilariae of a species of Cercopithifilaria from a dog in Sicily
    Domenico Otranto
    Dipartimento di Sanità Pubblica e Zootecnia, Universita degli Studi di Bari, 70010 Valenzano, Bari, Italy
    Vet Parasitol 182:221-9. 2011
    ....
  69. ncbi Diagnosis of imported canine filarial infections in Germany 2008 - 2010
    Nikola Pantchev
    Division of IDEXX Laboratories, Vet Med Labor GmbH, Ludwigsburg, Germany
    Parasitol Res 109:S61-76. 2011
    ..repens, A. reconditum or D. dracunculoides, whereas a topical moxidectin/imidacloprid formulation was able to eliminate microfilariae in one dog infected with A. reconditum...
  70. ncbi Rhipicephalus sanguineus (Ixodida, Ixodidae) as intermediate host of a canine neglected filarial species with dermal microfilariae
    E Brianti
    Dipartimento di Sanità Pubblica Veterinaria, Facolta di Medicina Veterinaria, Universita degli Studi di Messina, Messina, Italy
    Vet Parasitol 183:330-7. 2012
    ..can ingest microfilariae, which develop up to the third infective stage thus suggesting that this tick species might act as an intermediate host of this little known canine filarioid...
  71. pmc Efficacy of slow-release collar formulations of imidacloprid/flumethrin and deltamethrin and of spot-on formulations of fipronil/(s)-- methoprene, dinotefuran/pyriproxyfen/permethrin and (s) -methoprene/amitraz/fipronil against Rhipicephalus sanguineus an
    Ivan G Horak
    Department of Zoology and Entomology, University of the Free State, Bloemfontein 9301, South Africa
    Parasit Vectors 5:79. 2012
    ....
  72. ncbi The northward spread of leishmaniasis in Italy: evidence from retrospective and ongoing studies on the canine reservoir and phlebotomine vectors
    Michele Maroli
    Istituto Superiore di Sanita, Rome, Italy
    Trop Med Int Health 13:256-64. 2008
    ..Northern continental Italy is now focally endemic for VL and a moderate risk for human disease does exist, although the intensity of transmission seems to be lower than in traditional settings of Mediterranean VL...
  73. ncbi The brown dog tick, Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae): from taxonomy to control
    Filipe Dantas-Torres
    Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes, Fundacao Oswaldo Cruz, Caixa Postal 7472, Avenida Professor Moraes Rego s n, Campus UFPE, Recife, Pernambuco, Brazil
    Vet Parasitol 152:173-85. 2008
    ..sanguineus, highlighting the potential risks associated to the improper use of acaricides, such as environmental pollution and toxicity to humans and other non-target organisms (e.g., tick predators)...
  74. ncbi New insights into the ecology and biology of Acanthocheilonema reconditum (Grassi, 1889) causing canine subcutaneous filariosis
    Emanuele Brianti
    Dipartimento di Sanità Pubblica Veterinaria, Universita degli Studi di Messina, Messina, Italy
    Parasitology 139:530-6. 2012
    ..reconditum developing forms were detected in 5·1% (4/78) of dissected fleas, but not in any of the 272 ticks. The study provides new insights into the biology and ecology of this dog filarioid in its definitive and intermediate hosts...
  75. ncbi Epidemiologic and zoonotic aspects of ascarid infections in dogs and cats
    Alice C Y Lee
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Campus Road, Ithaca, NY 14853, USA
    Trends Parasitol 26:155-61. 2010
    ..Establishment of national surveillance programs to determine the incidence and specific etiological agent in human larva migrans patients would aid in the development of targeted intervention strategies...
  76. ncbi Prevalence, distribution and risk associated with tick infestation of dogs in Great Britain
    F D Smith
    Veterinary Parasitology and Ecology Group, School of Biological Sciences, University of Bristol, U K
    Med Vet Entomol 25:377-84. 2011
    ..This study is of value because, unusually, it presents the results of a randomized sample of dogs and gives a prevalence which is higher than those previously recorded in Great Britain...
  77. ncbi Parasite density and impaired biochemical/hematological status are associated with severe clinical aspects of canine visceral leishmaniasis
    Alexandre B Reis
    Laboratório de Parasitologia e Histopatologia, Núcleo de Pesquisas em Ciências Biológicas NUPEB, Instituto de Ciências Exatas e Biológicas, Universidade Federal de Ouro Preto, Rua Costa Sena, Minas Gerais, Brazil
    Res Vet Sci 81:68-75. 2006
    ..Finally, we believe that the follow-up of these parameters could be a relevant approach to be used as markers during therapeutic and vaccine evaluations...
  78. ncbi Transcriptomic "portraits" of canine mammary cancer cell lines with various phenotypes
    M Krol
    Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences SGGW, Warsaw, Poland
    J Appl Genet 51:169-83. 2010
    ..Metastatic properties of mammary cancer cells seem to be associated with elevated expression of PGP (P glycoprotein), SEMA3B (semaphorin 3B), and STIM1 (stromal interaction molecule 1)...
  79. pmc Use of an activity monitor to detect response to treatment in dogs with osteoarthritis
    Dorothy Cimino Brown
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Vet Med Assoc 237:66-70. 2010
    ..To determine whether an activity monitor (AM) could be used to detect changes in activity in dogs with osteoarthritis treated with carprofen or a placebo...
  80. pmc Prevalence of Dirofilaria immitis, Ehrlichia canis, Borrelia burgdorferi sensu lato, Anaplasma spp. and Leishmania infantum in apparently healthy and CVBD-suspect dogs in Portugal--a national serological study
    Luis Cardoso
    Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tras os Montes e Alto Douro, Vila Real, Portugal
    Parasit Vectors 5:62. 2012
    ..The present study aimed at assessing the seroprevalence of infection with or exposure to Dirofilaria immitis, Ehrlichia canis, Borrelia burgdorferi sensu lato, Anaplasma spp. and Leishmania infantum in dogs in Portugal...
  81. pmc Current situation of Leishmania infantum infection in shelter dogs in northern Spain
    Guadalupe Miró
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain
    Parasit Vectors 5:60. 2012
    ..Besides L. infantum infection, the epidemiological role of variables like sex, breed and age was also assessed...
  82. pmc MTM1 mutation associated with X-linked myotubular myopathy in Labrador Retrievers
    Alan H Beggs
    Division of Genetics and Program in Genomics, The Manton Center for Orphan Disease Research at Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 107:14697-702. 2010
    ..These data demonstrate that XLMTM in Labrador Retrievers is a faithful genetic model of the human condition...
  83. ncbi Impact of canine control on the epidemiology of canine and human visceral leishmaniasis in Brazil
    C B Palatnik-de-Sousa
    Department of General Microbiology, , Federal University of Rio de Janeiro, Brazil
    Am J Trop Med Hyg 65:510-7. 2001
    ....
  84. ncbi Association between anal sac gland carcinoma and dog leukocyte antigen-DQB1 in the English Cocker Spaniel
    J Aguirre-Hernandez
    Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, UK
    Tissue Antigens 76:476-81. 2010
    ....
  85. ncbi Macrocyclic lactone resistance in Dirofilaria immitis
    Catherine Bourguinat
    Institute of Parasitology, McGill University, 21111 Lakeshore Road, Sainte Anne de Bellevue, Quebec H9X3V9, Canada
    Vet Parasitol 181:388-92. 2011
    ..3% in microfilariae that survived repeated treatments with high doses of ML anthelmintics. The data show phenotypic and genotypic evidence of ML resistance in Dirofilaria immitis...
  86. ncbi Prevention of endemic canine vector-borne diseases using imidacloprid 10% and permethrin 50% in young dogs: a longitudinal field study
    D Otranto
    Dipartimento di Sanità Pubblica e Zootecnia, Universita degli Studi di Bari, Valenzano, BA, Italy
    Vet Parasitol 172:323-32. 2010
    ..The results demonstrate that ImPer preventive treatment against arthropods protects autochthonous and naïve beagle dogs against CVBD-causing pathogens...
  87. ncbi Current status of human rabies transmitted by dogs in Latin America
    Maria Cristina Schneider
    Veterinary Public Health Unit, Pan American Health Organization, Washington, DC 20037 2895, USA
    Cad Saude Publica 23:2049-63. 2007
    ..Samples sent for rabies testing represent 0.05% of the estimated canine population (range: 0.001 to 0.2%). The countries are quite close to achieving the goal...
  88. ncbi Flea and tick control in the 21st century: challenges and opportunities
    Michael Wayne Dryden
    Department of Diagnostic Medicine Pathobiology, Kansas State University, Manhattan, KS 66506, USA
    Vet Dermatol 20:435-40. 2009
    ..These factors probably cause most real and perceived product failures...
  89. ncbi Cerebellar cortical degeneration with selective granule cell loss in Bavarian mountain dogs
    T Flegel
    Department of Small Animal Medicine, University of Leipzig, An den Tierkliniken 23, 04103 Leipzig, Germany
    J Small Anim Pract 48:462-5. 2007
    ....
  90. ncbi Clinical, parasitologic, and immunologic evolution in dogs experimentally infected with sand fly-derived Leishmania chagasi promastigotes
    Bruno L Travi
    University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
    Am J Trop Med Hyg 81:994-1003. 2009
    ..On the basis of the data obtained from this study, a sample size analysis using different endpoints for future vaccine trials is described...
  91. ncbi A SYBR green real-time PCR assay for the detection of the nematode Angiostrongylus vasorum in definitive and intermediate hosts
    R Jefferies
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, United Kingdom
    Vet Parasitol 166:112-8. 2009
    ..Real-time quantitative PCR offers a more efficient means of detecting A. vasorum infection with a lower limit of detection than traditional diagnostic tests, and it therefore has important clinical and epidemiological applications...
  92. ncbi Prevalence of flea infestation in dogs and cats in Hungary combined with a survey of owner awareness
    R Farkas
    Department of Parasitology and Zoology, Faculty of Veterinary Science, Szent Istvan University, Budapest, Hungary
    Med Vet Entomol 23:187-94. 2009
    ..Very few owners reported having attempted to kill fleas in their animals' environment; instead, they believed that fleas were acquired from other cats or dogs...
  93. ncbi The efficacy of collars impregnated with flumethrin and propoxur against experimental infestations of adult Rhipicephalus sanguineus on dogs
    L J Fourie
    Department of Zoology and Entomology, University of the Free State, PO Box 339, Bloemfontein 9301, South Africa
    J S Afr Vet Assoc 74:123-6. 2003
    ..The mean tick counts on the 2 groups of collared dogs did not differ significantly (P < 0.0001) for any of the assessment days...
  94. ncbi Evidence of inheritance of intrahepatic portosystemic shunts in Irish Wolfhounds
    F G van Steenbeek
    Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    J Vet Intern Med 23:950-2. 2009
    ..The etiogenesis of congenital portosystemic shunt in dogs is not understood. In Irish Wolfhounds, intrahepatic portosystemic shunt (IHPSS) is thought to be hereditary, but the mode of inheritance is unknown...
  95. ncbi Psychometric testing of the Helsinki chronic pain index by completion of a questionnaire in Finnish by owners of dogs with chronic signs of pain caused by osteoarthritis
    Anna K Hielm-Björkman
    Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, FIN 00014, Finland
    Am J Vet Res 70:727-34. 2009
    ..To determine the validity, reliability, and sensitivity of a published chronic pain index by completion of a questionnaire in Finnish by owners of dogs with chronic signs of pain caused by osteoarthritis...
  96. ncbi Heartworm and Wolbachia: therapeutic implications
    J W McCall
    Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, USA
    Vet Parasitol 158:204-14. 2008
    ..Preliminary observations suggest that administration of DOXY+IVM for several months prior to (or without) MEL will eliminate adult HW with less potential for severe thromboembolism than MEL alone...
  97. pmc Ability of the canine brief pain inventory to detect response to treatment in dogs with osteoarthritis
    Dorothy Cimino Brown
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Vet Med Assoc 233:1278-83. 2008
    ..To determine whether the Canine Brief Pain Inventory (CBPI) can detect changes in dogs with osteoarthritis treated with an NSAID or a placebo...
  98. ncbi Ixodid tick species attaching to dogs in Hungary
    Gábor Földvári
    Department of Parasitology and Zoology, Faculty of Veterinary Science, St Istvan University, P O Box 2, Budapest H 1400, Hungary
    Vet Parasitol 129:125-31. 2005
    ..Our data contribute to the understanding of geographical and seasonal distribution of ixodid tick species infesting dogs in Hungary. The implication of these data, for the risk of canine tick borne diseases is discussed...
  99. ncbi Histological grading and prognosis in dogs with mammary carcinomas: application of a human grading method
    M Karayannopoulou
    Department of Clinical Studies, School of Veterinary Medicine, Aristotle University of Thessaloniki, St Voutyra 11, 546 27, Thessaloniki, Greece
    J Comp Pathol 133:246-52. 2005
    ..001). Routine use of this human grading method would help the clinician to make a more accurate prognosis in the interests of post-surgical management in dogs with mammary carcinomas...
  100. ncbi Tick-borne infectious diseases of dogs
    S E Shaw
    Dept of Clinical Veterinary Sciences, University of Bristol, Langford House, Langford, Bristol, UK BS40 5DU
    Trends Parasitol 17:74-80. 2001
    ....
  101. ncbi Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals
    L Gradoni
    Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy
    Vaccine 23:5245-51. 2005
    ..We conclude that vaccination with MML is not effective to prevent leishmaniasis infection and disease progression in dogs under field conditions...

Research Grants40

  1. Transcription Regulation and Biological Function of NAG1
    SEUNG BAEK; Fiscal Year: 2005
    ..Cancer and inflammation are certainly environmentally relevant problems and thus this project will provide new clues to aid in the understanding of how these drugs alter tumor development. ..
  2. AUTOSOMAL MECHANISMS OF TESTIS INDUCTION
    VICKI MEYERS WALLEN; Fiscal Year: 2005
    ..At the end of this grant period, we will have identified the gene causing this disorder and the step in the testis pathway that is altered by the mutation in timing, quantity, or location of gene expression. ..
  3. Enteric flora modulates the development of colitis
    Albert Jergens; Fiscal Year: 2008
    ..g., graduate students and postdoctoral fellow). There are ample opportunities to attend seminars, journal clubs and work-in-progress research meetings during which the applicant can become engaged in scientific discussions. ..
  4. Interdisciplinary Research Training for Veterinarians
    Lisa Freeman; Fiscal Year: 2008
    ..These evaluations, continued refinement, and the commitment of the program faculty will help to ensure that this becomes a self-sustaining program. ..
  5. The molecular basis for an animal model of inherited hyperuricosuria
    Danika Bannasch; Fiscal Year: 2007
    ..The elucidation of a novel gene function should provide new avenues of investigation for the treatment of the human condition. [unreadable] [unreadable] [unreadable]..
  6. Canine Brain Tumors - A New Model for Gene Discovery
    Matthew Breen; Fiscal Year: 2006
    ..Characterization of these genetic loci will help to improve the definition of molecular risk and prognosis of human and canine brain tumors, with a potentially major impact on human health. ..
  7. Resistant E.coli in Humans and Poultry
    James Johnson; Fiscal Year: 2005
    ..Does the research address a current and compelling problem of antimicrobial resistance that is of high public health importance and for which research is needed? [yes]. ..
  8. Cell-FIV: Mucosal transmission and intervention
    MARY BURKHARD; Fiscal Year: 2005
    ..Vaginal challenge with cell-associated FIV will test the correlates of protection. ..
  9. Helicobacter pylori: Pathogenesis and Virulence
    Kenneth Simpson; Fiscal Year: 2005
    ....
  10. Canine model for assessing CNS access P-gp substrates
    KATRINA MEALEY; Fiscal Year: 2005
    ....
  11. Natural History of Borrelia lonestari
    Susan Little; Fiscal Year: 2006
    ..S., enhancing public health efforts in those areas where people are risk of infection; reduction in human disease from these pathogens should result. [unreadable] [unreadable] [unreadable] [unreadable]..
  12. Alloantigen exposure influences infection threshold
    MARY BURKHARD; Fiscal Year: 2006
    ..Because these therapies would work in a virus non-specific manner, they would have potential use at the population level against multiple virus subtypes. ..
  13. Nitogen reduction and xenobiotic response
    Lauren A Trepanier; Fiscal Year: 2010
    ..The ultimate goal of these studies is to find better ways to prevent these adverse reactions. ..
  14. Measure Validation and RCT- Dog Bone Cancer Pain Model
    Dorothy Brown; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  15. Trafficking, persistence and evolution of HIV in the CNS
    Peter Simmonds; Fiscal Year: 2005
    ....
  16. MOLECULAR PATHOGENESIS OF FELINE SPINAL MUSCULAR ATROPHY
    JOHN FYFE; Fiscal Year: 2002
    ..Initial candidate genes will be those implicated in human SMA, but otherwise a comparative positional-candidate gene approach will be taken. ..
  17. NEURONAL DEGENERATION HEREDITARY CEROID-LIPOFUSCINOSIS
    Martin Katz; Fiscal Year: 2003
    ....
  18. Protective Glycopeptide Immunodeterminants of Ehrlichia chaffeensis
    Jere W McBride; Fiscal Year: 2010
    ..chaffeensis. HME is an emerging public health concern, and this research will facilitate rational development of vaccines and therapeutics against the most prevalent life-threatening tick- borne disease in North America. ..
  19. Molecular Mechanism of Polarized Cubilin Expression
    JOHN FYFE; Fiscal Year: 2004
    ..Results of these efforts are expected to open a window onto a new aspect of nutrient absorption and membrane receptor biology. ..
  20. Targeted Intervention Against EphA2 on Cancer Cells
    DEBORAH KNAPP; Fiscal Year: 2004
    ..Upon conclusion of our studies, we will have validated EphA2 as a molecular target for cancer treatment and will have generated the reagents and expertise to exploit a critical vulnerability on malignant cells. ..
  21. Tissue engineered osteochondral patella resurfacing
    James Cook; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  22. CELL ASSOCIATED FIV--VAGINAL TRANSMISSION AND PROTECTION
    MARY BURKHARD; Fiscal Year: 2003
    ..Vaginal challenge with cell-associated FIV will test the correlates of protection. ..
  23. Pilot Study--Cox2 Inhibitor in Invasive Bladder Cancer
    DEBORAH KNAPP; Fiscal Year: 2002
    ..abstract_text> ..
  24. Nipah Virus Marker Vaccine and Companion Diagnostic Test
    James Roth; Fiscal Year: 2005
    ..abstract_text> ..
  25. MURINE MODEL FOR MONKEY B VIRUS INFECTION
    JERRY RITCHEY; Fiscal Year: 2004
    ..abstract_text> ..
  26. Regulation of the survival motor neuron gene
    CHARLOTTE SUMNER; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  27. Influence of cell-bound Stx on cytokine production
    SHANNON HOSTETTER; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  28. Proteomic Discovery of Biomaterial Antigens
    E Orton; Fiscal Year: 2007
    ..e. tissue engineering). This application provides information about immune rejection of biomaterials that must be better understood before animal tissues can be used in tissue engineering. [unreadable] [unreadable] [unreadable]..
  29. US with Submicron Bubbles for Sentinel Node Detection
    Erik Wisner; Fiscal Year: 2004
    ..Successful completion of this study will lead to an alternative method for intra-operative sentinel node localization that may obviate many of the limitations of current techniques. ..
  30. ITO IN DOGS WITH INHERITED VENTRICULAR ARRHYTHMIAS
    Bruce Kornreich; Fiscal Year: 2005
    ..abstract_text> ..
  31. Developing Avirulent Rabies Virus Vaccines
    Zhen F Fu; Fiscal Year: 2010
    ..Such characterists will make these recombinant RV vaccines particularly suitable for post-exposure treatment. ..
  32. c-Kit Mutations and Their Role in Tumor Biology
    Cheryl London; Fiscal Year: 2005
    ..abstract_text> ..
  33. Gene Transfer Therapy for Alport Syndrome
    George Lees; Fiscal Year: 2007
    ..It will also lay the foundation for gene transfer therapy of other glomerular iseases. ..
  34. Gene Therapy of Autosomal Recessive RP
    Simon Petersen Jones; Fiscal Year: 2006
    ..abstract_text> ..
  35. TRANSMISSION ELECTRON MICROSCOPE
    Martin Katz; Fiscal Year: 2006
    ..Broadening the user base will help make the cost per user of maintaining the instrument as low as possible. [unreadable] [unreadable]..
  36. Comparison of US and European Babesia divergens Isolates
    Patricia Holman; Fiscal Year: 2004
    ..The molecular aspects may provide information that will be useful in future efforts to devise diagnostic tests. ..
  37. MRI, MIT, and MRS of MPS VII and Krabbe Disease
    Charles Vite; Fiscal Year: 2003
    ..x0a; ..
  38. ANTIGEN PRESENTATION IN MALARIA INFECTION
    Anne Avery; Fiscal Year: 2002
    ..This is particularly important when planning vaccine strategies for endemic areas, where vaccines are likely to already harbor a malaria infection which could alter the way their immune system handles antigen. ..
  39. Vaccine induced resistance against E. granulosus in dogs
    Wenbao Zhang; Fiscal Year: 2007
    ..granulosus infection by vaccination with the recombinant proteins. We will test humoral and cellular responses generated during vaccination to determine possible correlations of the immune parameters with protection. ..