bovine mastitis

Summary

Summary: INFLAMMATION of the UDDER in cows.

Top Publications

  1. ncbi Survey of the incidence and aetiology of mastitis on dairy farms in England and Wales
    A J Bradley
    School of Clinical Veterinary Science, University of Bristol, Langford
    Vet Rec 160:253-7. 2007
  2. ncbi Bovine mastitis and intramammary drug delivery: review and perspectives
    P Gruet
    CEVA Sante Animale, Research and Development, BP126, F 33501 Libourne cedex, France
    Adv Drug Deliv Rev 50:245-59. 2001
  3. ncbi Effect of pathogen-specific clinical mastitis on milk yield in dairy cows
    Y T Grohn
    Section of Epidemiology, Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 87:3358-74. 2004
  4. doi Identification and characterization of methicillin-resistant coagulase-negative staphylococci from bovine mastitis
    Andrea T Fessler
    Institute of Farm Animal Genetics, Friedrich Loeffler Institut FLI, Neustadt Mariensee, Germany
    J Antimicrob Chemother 65:1576-82. 2010
  5. ncbi Invited Review: The role of cow, pathogen, and treatment regimen in the therapeutic success of bovine Staphylococcus aureus mastitis
    H W Barkema
    Dept of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, Canada
    J Dairy Sci 89:1877-95. 2006
  6. pmc Broad-spectrum activity against bacterial mastitis pathogens and activation of mammary epithelial cells support a protective role of neutrophil cathelicidins in bovine mastitis
    Linda Tomasinsig
    Department of Biomedical Sciences and Technology, University of Udine, Udine, Italy
    Infect Immun 78:1781-8. 2010
  7. doi Characterization of methicillin-resistant Staphylococcus aureus ST398 from cases of bovine mastitis
    Andrea Fessler
    Institute of Farm Animal Genetics, Friedrich Loeffler Institut, Neustadt Mariensee, Germany
    J Antimicrob Chemother 65:619-25. 2010
  8. ncbi Analytical specificity and sensitivity of a real-time polymerase chain reaction assay for identification of bovine mastitis pathogens
    M T Koskinen
    Finnzymes Diagnostics, Keilaranta 16A, Espoo, Finland
    J Dairy Sci 92:952-9. 2009
  9. ncbi Invasive potential of bacterial isolates associated with subclinical bovine mastitis
    José L Anaya-López
    Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolas de Hidalgo, Apartado Postal 53, Administración Chapultepec Oriente, C P 58262 Morelia, Michoacan, Mexico
    Res Vet Sci 81:358-61. 2006
  10. ncbi Persistence in bovine mastitis of Staphylococcus aureus clones as assessed by random amplified polymorphic DNA analysis, ribotyping and biotyping
    V Myllys
    National Veterinary and Food Research Institute, Helsinki, Finland
    Vet Microbiol 57:245-51. 1997

Research Grants

  1. NOVEL ANTIMICROBIAL TREATMENT FOR MASTITIS
    RICHARD COUGHLIN; Fiscal Year: 2001
  2. Triple action chimera: eradication of nasal S. aureus by cell wall hydrolases
    DAVID DONOVAN; Fiscal Year: 2009
  3. Triple action chimera: eradication of nasal S. aureus by cell wall hydrolases
    DAVID MATTHEW DONOVAN; Fiscal Year: 2010
  4. VIRULENCE FACTORS OF GROUP B STREPTOCOCCI
    John Bohnsack; Fiscal Year: 2000
  5. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 2000
  6. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 1999
  7. VIRULENCE FACTORS OF GROUP B STREPTOCOCCI
    John Bohnsack; Fiscal Year: 2001
  8. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 2001
  9. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 2001
  10. VIRULENCE FACTORS OF GROUP B STREPTOCOCCI
    John Bohnsack; Fiscal Year: 1999

Detail Information

Publications265 found, 100 shown here

  1. ncbi Survey of the incidence and aetiology of mastitis on dairy farms in England and Wales
    A J Bradley
    School of Clinical Veterinary Science, University of Bristol, Langford
    Vet Rec 160:253-7. 2007
    ..Staphylococcus aureus and coagulase-positive staphylococci together accounted for 10 per cent of the samples with high somatic cell counts; 39 per cent produced no bacterial growth...
  2. ncbi Bovine mastitis and intramammary drug delivery: review and perspectives
    P Gruet
    CEVA Sante Animale, Research and Development, BP126, F 33501 Libourne cedex, France
    Adv Drug Deliv Rev 50:245-59. 2001
    ..g. liposomes, microparticles or nanoparticles) that allow uptake of the active component by phagocytes and thus prolong an enhanced antibacterial activity...
  3. ncbi Effect of pathogen-specific clinical mastitis on milk yield in dairy cows
    Y T Grohn
    Section of Epidemiology, Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 87:3358-74. 2004
    ..These findings provide dairy producers with more information on which pathogen-specific CM cases should receive treatment and how to manage these cows, thereby reducing CM impact on cow well being and profitability...
  4. doi Identification and characterization of methicillin-resistant coagulase-negative staphylococci from bovine mastitis
    Andrea T Fessler
    Institute of Farm Animal Genetics, Friedrich Loeffler Institut FLI, Neustadt Mariensee, Germany
    J Antimicrob Chemother 65:1576-82. 2010
    ....
  5. ncbi Invited Review: The role of cow, pathogen, and treatment regimen in the therapeutic success of bovine Staphylococcus aureus mastitis
    H W Barkema
    Dept of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, Canada
    J Dairy Sci 89:1877-95. 2006
    ..aureus infections is often justified based on bacteriological cure and economic outcome, whereas treatment of older animals, chronic infections, or penicillin-resistant isolates should be discouraged...
  6. pmc Broad-spectrum activity against bacterial mastitis pathogens and activation of mammary epithelial cells support a protective role of neutrophil cathelicidins in bovine mastitis
    Linda Tomasinsig
    Department of Biomedical Sciences and Technology, University of Udine, Udine, Italy
    Infect Immun 78:1781-8. 2010
    ..and in lipopolysaccharide (LPS)-treated cells, to determine their activities against bacteria isolated from bovine mastitis, and to examine their potentials to trigger defense responses in bovine mammary cells...
  7. doi Characterization of methicillin-resistant Staphylococcus aureus ST398 from cases of bovine mastitis
    Andrea Fessler
    Institute of Farm Animal Genetics, Friedrich Loeffler Institut, Neustadt Mariensee, Germany
    J Antimicrob Chemother 65:619-25. 2010
    ....
  8. ncbi Analytical specificity and sensitivity of a real-time polymerase chain reaction assay for identification of bovine mastitis pathogens
    M T Koskinen
    Finnzymes Diagnostics, Keilaranta 16A, Espoo, Finland
    J Dairy Sci 92:952-9. 2009
    ..Altogether, 643 culture isolates originating from clinical bovine mastitis, human, and companion animal samples were analyzed using the assay...
  9. ncbi Invasive potential of bacterial isolates associated with subclinical bovine mastitis
    José L Anaya-López
    Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolas de Hidalgo, Apartado Postal 53, Administración Chapultepec Oriente, C P 58262 Morelia, Michoacan, Mexico
    Res Vet Sci 81:358-61. 2006
    ..aureus control strain ATCC 27543. In conclusion, using the in vitro model of infection used in this study, differences in bacterial invasion capability may be detected...
  10. ncbi Persistence in bovine mastitis of Staphylococcus aureus clones as assessed by random amplified polymorphic DNA analysis, ribotyping and biotyping
    V Myllys
    National Veterinary and Food Research Institute, Helsinki, Finland
    Vet Microbiol 57:245-51. 1997
    Staphylococcus aureus isolates (N = 40) from bovine mastitis were characterized by random amplified polymorphic DNA-PCR (RAPD-PCR), ribotyping and biotyping...
  11. ncbi Production effects related to mastitis and mastitis economics in dairy cattle herds
    Henri Seegers
    Unit of Animal Health Management, UMR 708 ENVN INRA, National Veterinary School, BP 40706, 44307 Nantes Cedex 03, France
    Vet Res 34:475-91. 2003
    ..To support decision making for udder health control, it is necessary to use a marginal approach, based on the comparison of the losses avoided and the additional costs of modified plans, compared to the existing ones...
  12. doi Comparison of a commercialized phenotyping system, antimicrobial susceptibility testing, and tuf gene sequence-based genotyping for species-level identification of coagulase-negative staphylococci isolated from cases of bovine mastitis
    A Capurro
    National Veterinary Institute, SE 75189 Uppsala, Sweden
    Vet Microbiol 134:327-33. 2009
    ..The present study indicates that the studied phenotypic methods are unreliable for identification of CNS from bovine intra-mammary infections...
  13. doi Repeat-based subtyping and grouping of Staphylococcus aureus from human infections and bovine mastitis using the R-domain of the clumping factor A gene
    Kamaleldin B Said
    Department of Animal Science, McGill University, Ste Anne de Bellevue, Quebec H9X 3V9, Canada
    Diagn Microbiol Infect Dis 63:24-37. 2009
    ..DNA from isolates and strains of human infections and bovine mastitis were amplified and sequenced. Sequences of clfA from published strains were also analyzed...
  14. doi Characterization of Dutch Staphylococcus aureus from bovine mastitis using a Multiple Locus Variable Number Tandem Repeat Analysis
    Risma Ikawaty
    Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Vet Microbiol 136:277-84. 2009
    ..Locus Variable Number Tandem Repeat Analysis (MLVA) scheme with 6 loci which lacks most drawbacks on 85 bovine mastitis isolates from The Netherlands. For each locus the number of repeat units (RU) was calculated...
  15. ncbi Organ- and host-specific clonal groups of Staphylococcus aureus from human infections and bovine mastitis revealed by the clumping factor A gene
    Kamaleldin B Said
    Department of Animal Science, McGill University, Quebec, Canada
    Foodborne Pathog Dis 7:111-9. 2010
    ..R-domain of the clumping factor A gene in 95 isolates from different organs in human patients and from bovine mastitis, using polymerase chain reaction, sequencing, multiple sequence alignment, and phylogenetic relationships...
  16. ncbi Clinical characteristics and persistence of bovine mastitis caused by different species of coagulase-negative staphylococci identified with API or AFLP
    Suvi Taponen
    University of Helsinki, Faculty of Veterinary Medicine, Department of Clinical Veterinary Sciences, Finland
    Vet Microbiol 115:199-207. 2006
    ..9%, as opposed to only 45.5% for untreated quarters. Bacterial cure rates for the most common CNS species or AFLP clusters were not statistically different. Further studies on identification of CNS species are needed...
  17. ncbi Bovine mastitis in Finland 2001--prevalence, distribution of bacteria, and antimicrobial resistance
    A Pitkälä
    National Veterinary and Food Research Institute, EELA, PB 45, FIN 00581 Helsinki, Finland
    J Dairy Sci 87:2433-41. 2004
    A nationwide survey was conducted in Finland to estimate prevalence of bovine mastitis, distribution of mastitis pathogens, and in vitro antimicrobial susceptibility of different mastitis pathogens...
  18. ncbi Mammary expression of new genes to combat mastitis
    D E Kerr
    Department of Animal Science, University of Vermont, Burlington 05405, USA
    J Anim Sci 81:38-47. 2003
    ..The transgenic approach to insertion of new genetic material into agriculturally important animals is feasible but requires extensive prior evaluation of the transgene and transgene product in model systems...
  19. doi Escherichia coli, but not Staphylococcus aureus triggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow
    Wolfram Petzl
    Clinic for Ruminants, Ludwig Maximilians University, Munich, Germany
    Vet Res 39:18. 2008
    ..Using the established mastitis model, the data clearly demonstrate a pathogen-dependent difference in the time kinetics of induced pathogen receptors and defense molecules...
  20. ncbi Monitoring udder health and milk quality using somatic cell counts
    Ynte H Schukken
    Quality Milk Production Services, Cornell Veterinary Medicine, Cornell University, 22 Thornwood Drive, Ithaca, NY 14850, USA
    Vet Res 34:579-96. 2003
    ..These programs are necessarily dynamic and complex. Implementation of complete udder health programs should be accompanied by research efforts to further fine-tune these complete udder health control and monitoring programs...
  21. ncbi Increase of Escherichia coli inoculum doses induces faster innate immune response in primiparous cows
    F Vangroenweghe
    Ghent University, Faculty of Veterinary Medicine, Department of Physiology, Biochemistry, and Biometrics, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Dairy Sci 87:4132-44. 2004
    ..coli infection efficiently. Moreover, increasing the inoculum dose induces a more rapid inflammatory reaction, mainly because of early activation of the innate host immune response...
  22. ncbi Virulence genes of bovine Staphylococcus aureus from persistent and nonpersistent intramammary infections with different clinical characteristics
    M Haveri
    Department of Clinical Veterinary Sciences, Faculty of Veterinary Medicine, University of Helsinki, Finland
    J Appl Microbiol 103:993-1000. 2007
    ..To examine, whether a possible relationship exists between genetic profile and infection persistence, clinical signs of infection, clonal type determined by pulsed-field gel electrophoresis (PFGE), and antimicrobial resistance...
  23. ncbi Comparison of antibiotic resistance of udder pathogens in dairy cows kept on organic and on conventional farms
    M Roesch
    Division of Nutrition and Physiology, Institute of Animal Genetics, Nutrition and Housing, University of Bern, CH 3012 Bern, Switzerland
    J Dairy Sci 89:989-97. 2006
    ..The antibiotic resistance status needs to be monitored in organic farms as well as conventional farms and production factors related to the absence of reduced antibiotic resistance in organic farms need to be evaluated...
  24. doi Alternative somatic cell count traits as mastitis indicators for genetic selection
    Y de Haas
    NRS, Animal Evaluation Unit, PO Box 454, NL 6800 AL Arnhem, The Netherlands
    J Dairy Sci 91:2501-11. 2008
    ..Therefore, use of information from a combination of different SCC traits may be more successful in improving overall udder health than the traditional single SCC measure...
  25. ncbi Elevated milk soluble CD14 in bovine mammary glands challenged with Escherichia coli lipopolysaccharide
    J W Lee
    Department of Animal Science, McGill University, Ste Anne de Bellevue, Quebec, H9X 3V9, Canada
    J Dairy Sci 86:2382-9. 2003
    ..The increase was not likely due to serum leakage. Instead, infiltrated neutrophils might be the main source of increased sCD14 in milk during inflammation...
  26. ncbi Milk culture results in a large Norwegian survey--effects of season, parity, days in milk, resistance, and clustering
    O Osterås
    Department of Norwegian Cattle Health Services, TINE Norwegian Dairies BA, As, Norway
    J Dairy Sci 89:1010-23. 2006
    ..aureus was likely due to higher prevalence of Staph. aureus as a whole, but for CNS, there was also an additional increase caused by a higher proportional rate of penicillin resistance during the late indoor season...
  27. pmc Analysis of the real EADGENE data set: comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (open access publication)
    Florence Jaffrezic
    INRA, UR337, Jouy en Josas, France INRA_J
    Genet Sel Evol 39:633-50. 2007
    ..These analyses also emphasised a biological problem of cross-talk between infected and uninfected quarters which will have to be dealt with for further microarray studies...
  28. pmc Therapeutic Chlamydophila abortus and C. pecorum vaccination transiently reduces bovine mastitis associated with Chlamydophila infection
    Carolin Biesenkamp-Uhe
    Bayer HealthCare AG, Osterather Strasse 1a, D 50739 Köln, Germany
    Infect Immun 75:870-7. 2007
    ..pecorum are highly prevalent in cattle and have been associated with bovine mastitis. A prospective cohort study was conducted with a herd of 140 Holstein dairy cows to investigate the influence ..
  29. ncbi Severity of E. coli mastitis is mainly determined by cow factors
    Christian Burvenich
    Mammary gland and Mastitis Research Centre, Department of Physiology, Biochemistry and Biometrics, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Res 34:521-64. 2003
    ..coli, connection between endotoxins, tumor necrosis factor-alpha and nitric oxide, severity classification of E. coli mastitis, lifespan of neutrophils, host factors that influence severity, tissue damage and production loss...
  30. ncbi Conventional identification of Streptococcus uberis isolated from bovine mastitis in Argentinean dairy herds
    L Odierno
    Departamento de Microbiologia e Inmunologia, Facultad de Ciencias Exactas, Fisico Quimicas y Naturales, Universidad Nacional de Rio Cuarto, Ruta 36 Km 601, 5800 Rio Cuarto, Cordoba, Republica Argentina
    J Dairy Sci 89:3886-90. 2006
    ..this study was to evaluate a conventional scheme for identifying Streptococcus uberis strains isolated from bovine mastitis. Seventy-five gram-positive, catalase-negative cocci were collected from cows with mastitis from 19 dairy ..
  31. ncbi Relationship between antimicrobial drug usage and antimicrobial susceptibility of gram-positive mastitis pathogens
    M Pol
    Department of Dairy Science, University of Wisconsin, Madison 53706, USA
    J Dairy Sci 90:262-73. 2007
    ....
  32. pmc Acute phase response in two consecutive experimentally induced E. coli intramammary infections in dairy cows
    Leena Suojala
    Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, FI 04920 Saarentaus, Finland
    Acta Vet Scand 50:18. 2008
    ..A (SAA) and lipopolysaccharide binding protein (LBP) have suggested to be suitable inflammatory markers for bovine mastitis. The aim of the study was to investigate acute phase markers along with clinical parameters in two ..
  33. pmc Mastitis increases mammary mRNA abundance of beta-defensin 5, toll-like-receptor 2 (TLR2), and TLR4 but not TLR9 in cattle
    T Goldammer
    Molecular Biology Research Division, Research Institute for the Biology of Farm Animals, 18196 Dummerstorf, Germany
    Clin Diagn Lab Immunol 11:174-85. 2004
    ..Our data therefore suggest a significant contribution of the innate immune system to counteract mastitis and attribute a prominent effector function to the MEC...
  34. doi Prevalence and antimicrobial susceptibility of gram-negative bacteria isolated from bovine mastitis between 2003 and 2008 in Korea
    H M Nam
    National Veterinary Research and Quarantine Service, 480, Anyang City, Gyeonggi Do, 430 824, Republic of Korea
    J Dairy Sci 92:2020-6. 2009
    ..of this study was to assess trends in the prevalence and distribution of gram-negative bacteria isolated from bovine mastitis and their antimicrobial susceptibilities during a 6-yr period between 2003 and 2008 in Korea...
  35. ncbi Characterization of integrons-mediated antimicrobial resistance among Escherichia coli strains isolated from bovine mastitis
    Gui Qin Wang
    Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100094, PR China
    Vet Microbiol 127:73-8. 2008
    ..prevalence of antimicrobial resistance and class I integrons in Escherichia coli strains (n=58) isolated from bovine mastitis in Inner Mongolia, antimicrobial susceptibility and the presence of various types of integrons were ..
  36. ncbi Total and differential leucocyte counts and lymphocyte subpopulations in lymph, afferent and efferent to the supramammary lymph node, during endotoxin-induced bovine mastitis
    S Lun
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Reprod Domest Anim 42:126-34. 2007
    ....
  37. ncbi Staphylococcus aureus strains isolated from bovine mastitis: virulence, antibody production and protection from challenge in a mouse model
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, P O Box 12, Bet Dagan 50250, Israel
    FEMS Immunol Med Microbiol 35:99-106. 2003
    ..the virulence of Staphylococcus aureus and coagulase-negative staphylococci (CNS) isolated from cases of bovine mastitis. In addition, the model was used to evaluate the cross protection elicited by heterologous antibodies...
  38. ncbi Viral infections and bovine mastitis: a review
    G J Wellenberg
    Division of Infectious Diseases and Food Chain Quality, Institute for Animal Science and Health ID Lelystad, P O Box 65, 8200 AB, Lelystad, The Netherlands
    Vet Microbiol 88:27-45. 2002
    This review deals with the role of viruses in the aetiology of bovine mastitis. Bovine herpesvirus 1, bovine herpesvirus 4, foot-and-mouth disease virus, and parainfluenza 3 virus have been isolated from milk from cows with clinical ..
  39. doi Activity of bacteriocins synthesized by Bacillus thuringiensis against Staphylococcus aureus isolates associated to bovine mastitis
    Jose Eleazar Barboza-Corona
    Universidad de Guanajuato, Campus Irapuato Salamanca, División Ciencias de la Vida, Departamento de Ingeniería en Alimentos, Irapuato, Guanajuato, 36500, Mexico, Mexico
    Vet Microbiol 138:179-83. 2009
    Antimicrobial therapy is a useful tool to control bovine mastitis caused by Staphylococcus aureus, as consequence an increase in staphylococci resistant cases has been registered...
  40. ncbi Mammary tissue damage during bovine mastitis: causes and control
    X Zhao
    Department of Animal Science, McGill University, Ste Anne de Bellevue, Quebec, H9X 3V9, Canada
    J Anim Sci 86:57-65. 2008
    ....
  41. ncbi Antibacterial activity of thionin Thi2.1 from Arabidopsis thaliana expressed by bovine endothelial cells against Staphylococcus aureus isolates from bovine mastitis
    Alejandra Ochoa-Zarzosa
    Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolas de Hidalgo, Apdo Postal 53, Administración Chapultepec, C P 58262 Morelia, Michoacan, Mexico
    Vet Microbiol 127:425-30. 2008
    b>Bovine mastitis is mainly caused by Staphylococcus aureus and antimicrobial therapy, commonly used for its control, has resulted in an increase in the frequency of resistant staphylococci in recent years...
  42. doi Pathogen-dependent induction of cytokines and other soluble inflammatory mediators during intramammary infection of dairy cows
    D D Bannerman
    Bovine Functional Genomics Laboratory, Beltsville Agricultural Research Center, ARS, USDA, Beltsville, MD 20705, USA
    J Anim Sci 87:10-25. 2009
    ....
  43. ncbi Changes in blood and milk lymphocyte sub-populations during acute and chronic phases of Staphylococcus aureus induced bovine mastitis
    U Grönlund
    Department of Clinical Sciences, Division of Comparative Reproduction, Obstetrics and Udder Health, Faculty of Veterinary Medicine and Animal Sciences, Swedish University of Agricultural Sciences, P O Box 7039, Uppsala, Sweden
    Res Vet Sci 80:147-54. 2006
    ....
  44. pmc Cumulative risk of bovine mastitis treatments in Denmark, Finland, Norway and Sweden
    J P Valde
    Department of Production Animal Clinics and Sciences, The Norwegian School of Veterinary Science, Oslo, Norway
    Acta Vet Scand 45:201-10. 2004
    ..The study clearly demonstrated differences in bovine mastitis treatment patterns among the Nordic countries...
  45. ncbi Phenotypic and genetic characterisation of bacteriocin-producing strains of Staphylococcus aureus involved in bovine mastitis
    Janaína dos Santos Nascimento
    Departamento de Microbiologia Geral, Instituto de Microbiologia UFRJ, CCS Bloco 1, Cidade Universitaria, 21941 590, Rio de Janeiro, Brazil
    Vet Microbiol 85:133-44. 2002
    Fifty strains of Staphylococcus spp. isolated from bovine mastitis cases in several herds from different Argentinian provinces were screened for antimicrobial substances...
  46. ncbi Technical note: Antimicrobial susceptibility of Portuguese isolates of Staphylococcus aureus and Staphylococcus epidermidis in subclinical bovine mastitis
    S F Nunes
    Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinaria, Av Universidade Técnica, 1300 477 Lisbon, Portugal
    J Dairy Sci 90:3242-6. 2007
    To evaluate the antimicrobial resistance traits of staphylococci responsible for subclinical bovine mastitis in Portugal, the minimum inhibitory concentrations (MIC) of 7 antimicrobial agents, frequently administered for mastitis ..
  47. pmc Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection
    Douglas D Bannerman
    Bovine Functional Genomics Laboratory, USDA Agricultural Research Service ANRI, BARC East, Bldg 1040, Room 2, Beltsville, MD 20705 2350, USA
    Clin Diagn Lab Immunol 11:463-72. 2004
    ..coli and S. aureus and suggest that the limited cytokine response to S. aureus may contribute to the well-known ability of the bacterium to establish chronic intramammary infection...
  48. pmc Cow, farm, and management factors during the dry period that determine the rate of clinical mastitis after calving
    M J Green
    School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, LE12 5RD, United Kingdom
    J Dairy Sci 90:3764-76. 2007
    ..The research indicates that specific dry-period management strategies have an important influence on the rate of clinical mastitis during the next lactation...
  49. ncbi Molecular typing of enterotoxigenic Staphylococcus aureus isolated from bovine mastitis in Korea
    Suk Kyung Lim
    National Veterinary Research and Quarantine Service, Ministry of Agriculture and Forestry, Anyang, Kyonggido, South Korea
    J Vet Med Sci 66:581-4. 2004
    ..4% exhibited the same PFGE pattern I. Accordingly, although the enterotoxin-producing S. aureus isolates from bovine mastitis were genetically diverse, 1 common genotype prevailed on the farms, indicating that PFGE pattern I isolates ..
  50. ncbi Intramammary infusion of a live culture of Lactococcus lactis for treatment of bovine mastitis: comparison with antibiotic treatment in field trials
    Katja Klostermann
    Moorepark Food Research Centre, Teagasc, Moorepark, Fermoy, Co Cork, Ireland
    J Dairy Res 75:365-73. 2008
    ..The results of these trials suggest that live culture treatment with Lc. lactis DPC3147 may be as efficacious as common antibiotic treatments in some instances...
  51. ncbi Diagnosis of clinical bovine mastitis by fine needle aspiration followed by staining and scanning electron microscopy in a Prototheca zopfii outbreak
    Elizabeth Oliveira da Costa
    Research Nucleus on Mammary Gland and Milk Production, Department of Preventive Veterinary Medicine and Animal Health, Faculdade de Medicina Veterinaria e Zootecnia, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    Mycopathologia 158:81-5. 2004
    ..with microbiological examination and scanning electron microscopy were evaluated in diagnosis of clinical bovine mastitis in a Prototheca zopfii outbreak...
  52. ncbi Staphylococcus aureus exosecretions and bovine mastitis
    A Younis
    National Mastitis Reference Center, Kimron Veterinary Institute, Dagan, Israel
    J Vet Med B Infect Dis Vet Public Health 50:1-7. 2003
    ..An association was found between the combinations of expressed bands and the cow responses: the majority of the cases could be linked to the expression of bands B and C...
  53. ncbi Characterisation of isolates of Staphylococcus aureus from acute, chronic and subclinical mastitis in cows in Norway
    T Tollersrud
    National Veterinary Institute, Oslo, Norway
    APMIS 108:565-72. 2000
    Eighty-six Staphylococcus aureus isolates from cases of bovine mastitis were characterised biochemically and with respect to serotype, multilocus enzyme electrophoresis genotypes, antibiotic sensitivity, and production of enterotoxins A ..
  54. doi Efficacy of a teat dip containing the bacteriocin lacticin 3147 to eliminate Gram-positive pathogens associated with bovine mastitis
    Katja Klostermann
    Moorepark Food Research Centre, Teagasc, Moorepark, Fermoy, Co Cork, Ireland
    J Dairy Res 77:231-8. 2010
    ..Streptococcal challenges were reduced by 97% for Str. dysgalactiae and by 90% for Str. uberis. These trials showed that the teat dip is able to reduce mastitis pathogens on the teats of lactating cows...
  55. doi Protective effect of glutathione S-transferase-fused mutant staphylococcal enterotoxin C against Staphylococcus aureus-induced bovine mastitis
    Jing Chun Cui
    Department of Preventive Veterinary Science, School of Veterinary Medicine, Northeastern Agricultural University, Harbin 150030, PR China
    Vet Immunol Immunopathol 135:64-70. 2010
    ..aureus-induced bovine mastitis. Cows were immunized with the GST-mSEC plus alum adjuvant and then challenged with viable S...
  56. ncbi Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis in China
    D Shi
    College of Veterinary, Inner Mongolia Agricultural University, Inner Mongolia, China
    Transbound Emerg Dis 57:221-4. 2010
    ..30% (206 of 236) isolates were resistant to penicillin G. This result compares with the reports from other countries; the overall level of resistance was generally high for all antimicrobial agents tested...
  57. ncbi Molecular typing of Streptococcus uberis strains isolated from cases of bovine mastitis
    R J Wieliczko
    Department of Biological Science, University of Waikato, Private Bag 3105, Hamilton, New Zealand
    J Dairy Sci 85:2149-54. 2002
    ..00 per reaction), and provided reliable and reproducible results. Furthermore, when these assays were used in conjunction with each other, they provided a means of confirmation of the specific DNA fingerprint patterns obtained...
  58. ncbi The dynamics of Staphylococcus aureus intramammary infection in nine Danish dairy herds
    H D Larsen
    Danish Veterinary Laboratory, Copenhagen V, Denmark
    Vet Microbiol 71:89-101. 2000
    ..The results support the hypothesis that some S. aureus mastitis strains are more contagious, virulent or persistent than others. The human reservoir of S. aureus does not play a major role as a source of bovine intramammary infections...
  59. pmc The effect of sampling time and sample handling on the detection of Staphylococcus aureus in milk from quarters with subclinical mastitis
    Sandra M Godden
    Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, USA
    Can Vet J 43:38-42. 2002
    ..05). The ability to detect S. aureus in quarters with subclinical intramammary infection, as measured by the mean category of cfu/mL, was maximized in fresh or frozen premilking samples and in frozen postmilking samples...
  60. ncbi In vitro antimicrobial effect and in vivo preventive and therapeutic effects of partially purified lantibiotic lacticin NK34 against infection by Staphylococcus species isolated from bovine mastitis
    S Y Kim
    Department of Microbiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul 151 742, Korea
    J Dairy Sci 93:3610-5. 2010
    ..and coagulase-negative Staphylococcus (CNS, n=20) strains isolated from the raw milk of cows with subclinical bovine mastitis in the present study...
  61. pmc Evaluation of tandem repeats for MLVA typing of Streptococcus uberis isolated from bovine mastitis
    Florence B Gilbert
    INRA, UR1282, Infectiologie Animale et Santé Publique IASP, F 37380 Nouzilly, France
    BMC Vet Res 2:33. 2006
    Streptococcus uberis is a common cause of bovine mastitis and recommended control measures, based on improved milking practice, teat dipping and antibiotic treatment at drying-off, are poorly efficient against this environmental pathogen...
  62. pmc Clinical, epidemiological and molecular characteristics of Streptococcus uberis infections in dairy herds
    R N Zadoks
    Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL Utrecht, The Netherlands
    Epidemiol Infect 130:335-49. 2003
    ..uberis strains as well as within-cow and between-cow transmission of a limited number of S. uberis strains, with possible transfer of bacteria via the milking machine...
  63. ncbi Prototheca zopfii genotypes isolated from cow barns and bovine mastitis in Japan
    Takafumi Osumi
    Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa 252 8510, Japan
    Vet Microbiol 131:419-23. 2008
    This study is the first investigation on Japanese isolates of Prototheca zopfii from bovine mastitis and the cow-barn surroundings by molecular characterization to clarify routes of infection for bovine protothecal mastitis...
  64. doi Identification of a bovine mastitis Escherichia coli subset
    S Blum
    National Mastitis Reference Center, Division of Bacteriology, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, Bet Dagan, Israel
    Vet Microbiol 132:135-48. 2008
    Eleven Escherichia coli isolates from clinical bovine mastitis cases (mastitic strains) and 11 from the cowshed environment (environmental strains) were compared, to determine if the former were a subset of the latter...
  65. pmc Sortase anchored proteins of Streptococcus uberis play major roles in the pathogenesis of bovine mastitis in dairy cattle
    James A Leigh
    The School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire, LE12 5RD, United Kindgom
    Vet Res 41:63. 2010
    ..These data demonstrate that a number of sortase anchored proteins each play a distinct, non-redundant and important role in pathogenesis of S. uberis infection within the lactating bovine mammary gland...
  66. ncbi Epidemiological and clinical aspects of the first outbreak of bovine mastitis caused by Prototheca zopfii in Goiás State, Brazil
    Válter Ferreira Félix Bueno
    Centro de Pesquisa em Alimentos, Escola de Veterinaria, Universidade Federal de Goias, Brazil
    Mycopathologia 161:141-5. 2006
    The purpose of this survey was to describe the occurrence of bovine mastitis caused by Prototheca zopfii in Goiás State, Brazil. Samples of milk, environment and udder were taken from a herd of 120 Holstein cows...
  67. ncbi Lipocalin-type prostaglandin D synthase in milk: a new biomarker for bovine mastitis
    R Baeker
    Brandenburg State Laboratory of Veterinary Diagnostics and Food Analysis, Potsdam, Germany
    Prostaglandins Other Lipid Mediat 67:75-88. 2002
    ..A database search could identify the four spots as isoforms of the bovine prostaglandin D synthase (PGD-S). In one of the isoforms a defined cysteine residue was shown to be oxidized to a sulfonic acid...
  68. doi Host response in bovine mastitis experimentally induced with Staphylococcus chromogenes
    H Simojoki
    University of Helsinki, Department of Production Animal Medicine, Pohjoinen Pikatie 800, 04920 Saarentaus, Finland
    Vet Microbiol 134:95-9. 2009
    ..In conclusion, this experimental model could be used to study host response in CNS mastitis caused by the main CNS species and also for comparison of the host response in a mild intramammary infection and in more severe mastitis models...
  69. pmc MRSA transmission between cows and humans
    Eva Juhász-Kaszanyitzky
    Central Veterinary Institute, Budapest, Hungary
    Emerg Infect Dis 13:630-2. 2007
    ..To our knowledge, this finding indicates the first documented case of direct transmission of MRSA between cows and humans...
  70. pmc Molecular epidemiology of Streptococcus uberis isolates from dairy cows with mastitis
    P Phuektes
    Veterinary Preclinical Centre, Faculty of Veterinary Science, The University of Melbourne, Melbourne, Victoria, Australia
    J Clin Microbiol 39:1460-6. 2001
    ..uberis infections are epidemiologically complex and that the relative importance of these factors in the occurrence of mastitis may differ between herds...
  71. ncbi Duration of infection and strain variation in Streptococcus uberis isolated from cows' milk
    S McDougall
    Animal Health Centre, Morrinsville, New Zealand
    J Dairy Sci 87:2062-72. 2004
    ..uberis infections, and that glands may be infected with multiple S. uberis PFGE types over a lactation...
  72. ncbi Use of the surface proteins GapC and Mig of Streptococcus dysgalactiae as potential protective antigens against bovine mastitis
    Alexandra Bolton
    Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, Canada
    Can J Microbiol 50:423-32. 2004
    Streptococcus dysgalactiae is a significant pathogen associated with bovine mastitis in lactating and nonlactating dairy cows, causing a severe inflammatory response of the mammary gland, which results in major economic losses to the ..
  73. ncbi Ribotyping of Streptococcus uberis from a dairy's environment, bovine feces and milk
    Ruth N Zadoks
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA Quality Milk Production Services, 22 Thornwood Drive, Cornell University, Ithaca, NY 14850 1263, USA
    Vet Microbiol 109:257-65. 2005
    Streptococcus uberis is a major cause of bovine mastitis and infections commonly result from environmental exposure to the pathogen. To identify specific sources of mastitis-causing S...
  74. ncbi National intervention study of mastitis control in dairy herds in England and Wales
    M J Green
    School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK
    Vet Rec 160:287-93. 2007
    ..There were also significant reductions of approximately 20 per cent in the incidence of clinical mastitis and in the occurrence of increases in the somatic cell counts of individual cows from below, to above 200,000 cells/ml...
  75. ncbi Adhesion and invasion of Escherichia coli from single and recurrent clinical cases of bovine mastitis in vitro
    D Döpfer
    Department of Bacteriology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3484 CL, Utrecht, The Netherlands
    Vet Microbiol 74:331-43. 2000
    Seven strains of Escherichia coli, originating from clinical cases of bovine mastitis, and one Salmonella typhimurium control strain were tested for their ability to adhere to, and invade, bovine mammary epithelial cells (MAC-T cells) in ..
  76. ncbi Determination of epidemiological relationships of Streptococcus agalactiae isolated from bovine mastitis
    Kristin Merl
    Regierungspräsidium Darmstadt, Veterinärdezernat, Luisenplatz 2, D 64283, Darmstadt, Germany
    FEMS Microbiol Lett 226:87-92. 2003
    ..agalactiae strain or at least closely related subtypes of this strain were responsible for the mastitis situation of the seven farms...
  77. ncbi Genetics of resistance to mastitis in dairy cattle
    Rachel Rupp
    INRA, Station d Amélioration Génétique des Animaux, BP 27, 31326 Castanet Tolosan, France
    Vet Res 34:671-88. 2003
    ....
  78. pmc Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection
    Ylva C Strandberg Lutzow
    Co operative Research Centre for Innovative Dairy Products, Australia
    BMC Vet Res 4:18. 2008
    ..Moreover, the effect of infection on the presence of bioactive innate immune proteins in milk is also unclear. The nature of these responses may determine the susceptibility of the tissue and its ability to resolve the infection...
  79. pmc Genome sequence survey identifies unique sequences and key virulence genes with unusual rates of amino Acid substitution in bovine Staphylococcus aureus
    Lisa L Herron
    Department of Veterinary Pathobiology and Biomedical Genomics Center, University of Minnesota, St Paul, Minnesota 55108, USA
    Infect Immun 70:3978-81. 2002
    ..We here present the results of a comparative genomic analysis between a bovine mastitis-associated clone, RF122, and the recently sequenced human-associated clones, Mu50 and N315, of Staphylococcus ..
  80. pmc Expression of a beta-defensin mRNA, lingual antimicrobial peptide, in bovine mammary epithelial tissue is induced by mastitis
    Kara Swanson
    Dairy Biotechnology, AgResearch, Hamilton, New Zealand
    Infect Immun 72:7311-4. 2004
    ..In situ hybridization showed that LAP mRNA was expressed in epithelial cells of mastitic tissue. These results suggest that LAP plays a role in the innate immune response to mastitis...
  81. pmc Molecular and genetic characterization of a novel nisin variant produced by Streptococcus uberis
    Ruth E Wirawan
    Department of Microbiology and Immunology, University of Otago, P O Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 72:1148-56. 2006
    Streptococcus uberis is one of the principal causative agents of bovine mastitis. In this study, we report that S. uberis strain 42 produces a lantibiotic, nisin U, which is 78% identical (82% similar) to nisin A from Lactococcus lactis...
  82. ncbi Bovine mastitis: an evolving disease
    A Bradley
    Division of Animal Health and Husbandry, Department of Clinical Veterinary Science, University of Bristol, Langford House, Langford, Bristol, BS40 5DU, UK
    Vet J 164:116-28. 2002
    ..Escherichia coli and Streptococcus uberis are now the two most common causes of bovine mastitis and are an increasing problem in low somatic cell count herds...
  83. doi Coagulase-negative staphylococci as cause of bovine mastitis- not so different from Staphylococcus aureus?
    Suvi Taponen
    University of Helsinki, Department of Production Animal Medicine, Helsinki, Finland
    Vet Microbiol 134:29-36. 2009
    ..Staphylococci are the bacteria most commonly isolated from bovine mastitis, and CNS are now predominant over S. aureus in most countries...
  84. ncbi Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis
    Douglas D Bannerman
    Bovine Functional Genomics Laboratory, Beltsville Agricultural Research Center, USDA Agricultural Research Service, Beltsville, MD 20705, USA
    Vet Res 35:681-700. 2004
    ..marcescens infection. Together, these data demonstrate the variability of the innate immune response to two distinct mastitis pathogens...
  85. ncbi Geographical variation in the presence of genes encoding superantigenic exotoxins and beta-hemolysin among Staphylococcus aureus isolated from bovine mastitis in Europe and USA
    H D Larsen
    Danish Veterinary Laboratory, Bulowsvej 27, DK 1790 Copenhagen V, Denmark
    Vet Microbiol 85:61-7. 2002
    ..exotoxins and beta-hemolysin among epidemiologically independent Staphylococcus aureus isolates from bovine mastitis. A total of 462 S...
  86. pmc Application of Streptococcus uberis multilocus sequence typing: analysis of the population structure detected among environmental and bovine isolates from New Zealand and the United Kingdom
    Gillian D Pullinger
    Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, United Kingdom
    Appl Environ Microbiol 72:1429-36. 2006
    ..Carriage of the hasA gene, which is necessary for capsule formation, correlated with clonal complex and isolation from clinical cases of mastitis...
  87. doi Pathogenomic analysis of the common bovine Staphylococcus aureus clone (ET3): emergence of a virulent subtype with potential risk to public health
    Caitriona M Guinane
    Centre for Infectious Diseases, The Chancellor s Building, New Royal Infirmary, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    J Infect Dis 197:205-13. 2008
    A common clone (ET3) of Staphylococcus aureus is responsible for a large proportion of cases of bovine mastitis and occasionally causes zoonotic infections of humans...
  88. ncbi Response of Staphylococcus aureus isolates from bovine mastitis to exogenous iron sources
    M S Diarra
    Dairy and Swine Research and Development Centre, Agriculture and Agri Food Canada, Lennoxville, QC, Canada
    J Dairy Sci 85:2141-8. 2002
    ..Possible functions of these lactoferrin-binding proteins could not be related to iron acquisition mechanism in S. aureus...
  89. ncbi Phenotypic and genetic antibiogram of methicillin-resistant staphylococci isolated from bovine mastitis in Korea
    J S Moon
    Department of Bacteriology, National Veterinary Research and Quarantine Service, Anyang, Gyeonggi Do, Republic of Korea
    J Dairy Sci 90:1176-85. 2007
    ..pathogens, whereas the coagulase-negative staphylococci (CNS) are also capable of causing opportunistic bovine mastitis. Many of these strains are resistant to penicillin or ampicillin because of the long-term use of beta-lactam ..
  90. ncbi Identification and epidemiological characterization of Streptococcus uberis isolated from bovine mastitis using conventional and molecular methods
    I U Khan
    Department of Environmental Health, Toxicology Division, 3223 Eden Ave, University of Cincinnati, Medical Center, Cincinnati, OH 45267 0056, USA
    J Vet Sci 4:213-24. 2003
    ..The generally unrelated DNA patterns indicated that S. uberis is a pathogen with multiple environmental habitats and that infections are caused by a great variety of strains...
  91. pmc Milk and serum J5-specific antibody responses, milk production change, and clinical effects following intramammary Escherichia coli challenge for J5 vaccinate and control cows
    David J Wilson
    Department of Population Medicine and Diagnostic Sciences, Cornell University, Ithaca, New York 14850, USA
    Clin Vaccine Immunol 14:693-9. 2007
    ..Vaccination with J5 was significantly associated with higher production of J5-specific IgG1 and IgG2 in early lactation, reduced SCC, faster clearance of E. coli from milk, and less milk production loss following intramammary challenge...
  92. ncbi Characterization of a Staphylococcus aureus small colony variant (SCV) associated with persistent bovine mastitis
    Heba Atalla
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    Foodborne Pathog Dis 5:785-99. 2008
    Staphylococcus aureus is a common cause of bovine mastitis and foodborne and other diseases in humans. This study tested the hypothesis that small colony variants (SCVs) of S. aureus are implicated in chronic bovine mastitis. Six S...
  93. pmc Hyperinvasive neonatal group B streptococcus has arisen from a bovine ancestor
    Naiel Bisharat
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
    J Clin Microbiol 42:2161-7. 2004
    ..Split decomposition analysis revealed that the human isolate ST-17 complex, the major hyperinvasive neonatal clone, has recently arisen from a bovine lineage...
  94. ncbi A partial budget model to estimate economic benefits of lactational treatment of subclinical Staphylococcus aureus mastitis
    J M Swinkels
    Innovet Bovine Herd Health Consultancy, Noordbeemster, 1463 PJ, The Netherlands
    J Dairy Sci 88:4273-87. 2005
    ..Although the economic outcome of lactational treatment of subclinical S. aureus mastitis is highly herd-, cow-, and strain-dependent, treatment is economically justified in many situations...
  95. ncbi Short-term changes of mRNA expression of various inflammatory factors and milk proteins in mammary tissue during LPS-induced mastitis
    S Schmitz
    Institute of Physiology, Technical University Munich, D 85354 Freising Weihenstephan, Germany
    Domest Anim Endocrinol 26:111-26. 2004
    ..05). In conclusion, mRNA expression of most inflammatory factors increased within hours, whereas that of most milk proteins remained unchanged...
  96. ncbi Phenotypic and genotypic characterization of bovine mastitis isolates of Staphylococcus aureus for biofilm formation
    Pradeep Vasudevan
    Department of Animal Science, Unit 40, University of Connecticut, 3636 Horsebarn Hill Road Extension, Storrs, CT 06269, USA
    Vet Microbiol 92:179-85. 2003
    ..aureus isolates from bovine mastitis. Thirty-two of the 35 isolates tested produced slime on Congo red agar, whereas only 24 of the isolates were ..
  97. ncbi The efficacy of bovine lactoferrin in the treatment of cows with experimentally induced Escherichia coli mastitis
    T Kutila
    Faculty of Veterinary Medicine, Department of Clinical Veterinary Sciences, Helsinki University, Helsinki, Finland
    J Vet Pharmacol Ther 27:197-202. 2004
    ..The concentration of lipopolysaccharide in milk compared with the number of bacteria was significantly lower in Lf than in enrofloxacin-treated cows (20 h PC)...
  98. ncbi Immunorelevant gene expression in LPS-challenged bovine mammary epithelial cells
    Ravi Pareek
    Department of Animal Science, Terrill Hall, University of Vermont, 570 Main Street, Burlington, VT 05405, USA
    J Appl Genet 46:171-7. 2005
    ..This cell culture model system provides evidence for an important role of the mammary epithelial cell in initiating the innate response to infection...
  99. ncbi Genetic parameters for clinical mastitis, somatic cell score, and production in the first three lactations of Swedish holstein cows
    E Carlen
    Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, PO Box 7023, 75007 Uppsala, Sweden
    J Dairy Sci 87:3062-70. 2004
    ..7), LSCS (>0.8), and production traits (>0.9), with the strongest correlations between second and third parity for all traits (>0.9 for udder health traits and close to unity for production traits)...
  100. ncbi Innate immune response of bovine mammary gland to pathogenic bacteria responsible for mastitis
    Javier Oviedo-Boyso
    Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolas de Hidalgo, Apdo Postal 53, Administración Chapultepec, C P 58262 Morelia, Michoacan, Mexico
    J Infect 54:399-409. 2007
    ..Knowledge, at the molecular level, of the mammary gland immune response during infection by pathogenic bacteria is fundamental to the design of effective therapies to control and eradicate bovine mastitis.
  101. ncbi The effect of selective dry cow treatment on new intramammary infections
    E A Berry
    Institute for Animal Health, Compton, Berkshire, United Kingdom
    J Dairy Sci 85:112-21. 2002
    ..It can be concluded that dry cow therapy continues to lower significantly the rate of new dry period intramammary infection in herds with elevated somatic cell counts and a high prevalence of infection...

Research Grants11

  1. NOVEL ANTIMICROBIAL TREATMENT FOR MASTITIS
    RICHARD COUGHLIN; Fiscal Year: 2001
    ..We propose to develop an novel anti-microbial therapy for bovine mastitis that would break farmer's dependence on human antibiotics...
  2. Triple action chimera: eradication of nasal S. aureus by cell wall hydrolases
    DAVID DONOVAN; Fiscal Year: 2009
    ..This study will explore a novel antimicrobial agent (a triple action chimeric viral enzyme) to eradicate S. aureus nasal colonization, since nasal carriage is a known risk factor for infection. ..
  3. Triple action chimera: eradication of nasal S. aureus by cell wall hydrolases
    DAVID MATTHEW DONOVAN; Fiscal Year: 2010
    ..This study will explore a novel antimicrobial agent (a triple action chimeric viral enzyme) to eradicate S. aureus nasal colonization, since nasal carriage is a known risk factor for infection. ..
  4. VIRULENCE FACTORS OF GROUP B STREPTOCOCCI
    John Bohnsack; Fiscal Year: 2000
    ..This approach will ultimately contribute to understanding the molecular basis of disease caused by GBS, and help devise strategies for preventing and treating this important cause of serious human neonatal bacterial infection. ..
  5. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 2000
    ..Results form these studies will provide the molecular basis of how Se deficiency can modify resistance to metabolic vascular disorders. ..
  6. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 1999
    ..Results form these studies will provide the molecular basis of how Se deficiency can modify resistance to metabolic vascular disorders. ..
  7. VIRULENCE FACTORS OF GROUP B STREPTOCOCCI
    John Bohnsack; Fiscal Year: 2001
    ..This approach will ultimately contribute to understanding the molecular basis of disease caused by GBS, and help devise strategies for preventing and treating this important cause of serious human neonatal bacterial infection. ..
  8. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 2001
    ..Results form these studies will provide the molecular basis of how Se deficiency can modify resistance to metabolic vascular disorders. ..
  9. OXIDANT STRESS AND ENDOTHELIAL CELL METABOLISM
    LORRAINE SORDILLO; Fiscal Year: 2001
    ..Results form these studies will provide the molecular basis of how Se deficiency can modify resistance to metabolic vascular disorders. ..
  10. VIRULENCE FACTORS OF GROUP B STREPTOCOCCI
    John Bohnsack; Fiscal Year: 1999
    ..This approach will ultimately contribute to understanding the molecular basis of disease caused by GBS, and help devise strategies for preventing and treating this important cause of serious human neonatal bacterial infection. ..