Genomes and Genes
Summary: A disease of cattle caused by parasitization of the red blood cells by bacteria of the genus ANAPLASMA.
Publications237 found, 100 shown here
- Nosocomial transmission of human granulocytic anaplasmosis in ChinaLijuan Zhang
National Institute of Communicable Disease Control and Prevention, China, CDC, Beijing, China, PO Box 5, Changping, Beijing, China 102206
JAMA 300:2263-70. 2008Human granulocytic anaplasmosis (HGA) is an emerging tick-borne disease in China...
- Borrelia miyamotoi infection presenting as human granulocytic anaplasmosis: a case reportHanumara Ram Chowdri
Hawthorn Medical Associates and St Luke s Hospital, New Bedford, Massachusetts, USA
Ann Intern Med 159:21-7. 2013..diseases, patients presenting with acute febrile illness with myalgia, headache, neutropenia, thrombocytopenia, and elevated hepatic aminotransferase levels are presumptively diagnosed as having human granulocytic anaplasmosis (HGA).
- The natural history of Anaplasma marginaleKatherine M Kocan
Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078 2007, USA
Vet Parasitol 167:95-107. 2010..Infection of cattle with A. marginale causes bovine anaplasmosis, a mild to severe hemolytic disease that results in considerable economic loss to both dairy and beef ..
- Human anaplasmosis in Belgium: a 10-year seroepidemiological studyChristel Cochez
Research Laboratory and Reference Laboratory for Vector borne Diseases, Queen Astrid Military Hospital, B 1120 Brussels, Belgium
Ticks Tick Borne Dis 2:156-9. 2011Human granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infection of neutrophils caused by Anaplasma phagocytophilum...
- Human ehrlichiosis and anaplasmosisNahed Ismail
Department of Pathology, Meharry Medical College, Nashville, TN 37208, USA
Clin Lab Med 30:261-92. 2010Human ehrlichiosis and anaplasmosis are acute febrile tick-borne diseases caused by various members of the genera Ehrlichia and Anaplasma (Anaplasmataceae)...
- Anaplasmosis in dogs: the relation of haematological, biochemical and clinical alterations to antibody titre and PCR confirmed infectionUrska Ravnik
Small Animal Clinic, Veterinary Faculty, University of Ljubljana, Cesta v Mestni log 47, SI 1000 Ljubljana, Slovenia
Vet Microbiol 149:172-6. 2011..phagocytophilum in a particular patient...
- Ehrlichiosis and anaplasmosis in dogs and catsSusan E Little
Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
Vet Clin North Am Small Anim Pract 40:1121-40. 2010..been made in our understanding of the diversity of the rickettsial organisms responsible for ehrlichiosis and anaplasmosis in dogs and, occasionally, cats, the vectors capable of transmitting these agents, and the role these organisms ..
- Ehrlichiosis, babesiosis, anaplasmosis and hepatozoonosis in dogs from St. Kitts, West IndiesPatrick J Kelly
Ross University School of Veterinary Medicine, St Kitts, West Indies
PLoS ONE 8:e53450. 2013..Although tick-borne diseases are important causes of morbidity and mortality in dogs in tropical areas, there is little information on the agents causing these infections in the Caribbean...
- Emerging perspectives in the research of bovine babesiosis and anaplasmosisCarlos E Suarez
Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99164 6630, USA
Vet Parasitol 180:109-25. 2011..In addition, acute babesiosis and anaplasmosis can be prevented quite effectively by combining tick control and vaccination with living attenuated organisms...
- Anaplasma phagocytophilum in ruminants in EuropeZerai Woldehiwet
Veterinary Teaching Hospital, Leahurst, Neston, South Wirral, UK
Ann N Y Acad Sci 1078:446-60. 2006..More recently, a few cases of human granulocytic anaplasmosis (HGA) have been reported in some European countries, but it remains to be established whether the variants ..
- Epidemiology and control of human granulocytic anaplasmosis: a systematic reviewHongtao Jin
Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, Jilin Province, People s Republic of China
Vector Borne Zoonotic Dis 12:269-74. 2012Granulocytic anaplasmosis caused by Anaplasma phagocytophilum is an emerging tick-borne zoonosis worldwide...
- Comparative strain analysis of Anaplasma phagocytophilum infection and clinical outcomes in a canine model of granulocytic anaplasmosisDiana G Scorpio
Department of Molecular Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Vector Borne Zoonotic Dis 11:223-9. 2011..clinical disease in experimentally inoculated dogs similar to dogs with naturally acquired granulocytic anaplasmosis. Six hounds were inoculated intravenously with one human and two canine strains of A...
- Functional epitope core motif of the Anaplasma marginale major surface protein 1a and its incorporation onto bioelectrodes for antibody detectionPaula S Santos
Laboratório de Nanobiotecnologia, Instituto de Genética e Bioquímica, Universidade Federal de Uberlandia, Uberlandia, Brazil
PLoS ONE 7:e33045. 2012b>Anaplasmosis, a persistent intraerythrocytic infection of cattle by Anaplasma marginale, causes severe anemia and a higher rate of abortion, resulting in significant loss to both dairy and beef industries...
- Epidemiological analysis of tick-borne diseases in ZambiaMartin Simuunza
Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, Scotland, UK
Vet Parasitol 175:331-42. 2011..bovis), anaplasmosis (caused by Anaplasma marginale) and heartwater (caused by Ehrlichia ruminantium)...
- Application of a reverse line blot assay to the study of haemoparasites in cattle in UgandaC A L Oura
Department of Microbiology and Parasitology, Faculty of Vet Medicine, Makerere University, Kampala, Uganda
Int J Parasitol 34:603-13. 2004..mutans and possibly T. taurotragi and T. velifera, may also cause clinical disease. Overall, the results presented here highlight the complexity of tick-borne pathogen infections in cattle in Uganda...
- Detection of haemoparasites in cattle by reverse line blot hybridisation with a note on the distribution of ticks in SicilyK Georges
Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.165, 3508 TD Utrecht, The Netherlands
Vet Parasitol 99:273-86. 2001..lusitanicum, Rhipicephalus sanguineus group, R. bursa, Dermacentor marginatus, Haemaphysalis punctata, B. annulatus and I. ricinus...
- Epidemiological, clinical and laboratory characteristics of patients with human granulocytic anaplasmosis in SloveniaStanka Lotric-Furlan
Department of Infectious Diseases, University Medical Center Ljubljana, University of Ljubljana, Slovenia
Wien Klin Wochenschr 118:708-13. 2006Human granulocytic anaplasmosis (HGA) has been recently recognized as an emerging tick-borne disease. Several reports indicate the presence of infection with Anaplasma phagocytophilum in Europe...
- Competitive exclusion between piroplasmosis and anaplasmosis agents within cattleLoubna Dib
Institut Vétérinaire, Centre Universitaire El Tarf, Route de Matroha, El Tarf, Algeria
PLoS Pathog 4:e7. 2008
- Canine granulocytic anaplasmosis: a reviewD D Carrade
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
J Vet Intern Med 23:1129-41. 2009..phagocytophilum occurs after natural infection requires additional study, with most reports suggesting that anaplasmosis is a self-limiting disease in dogs that responds well to a 2-week course of doxycycline therapy.
- Relative efficiency of biological transmission of Anaplasma marginale (Rickettsiales: Anaplasmataceae) by Dermacentor andersoni (Acari: Ixodidae) compared with mechanical transmission by Stomoxys calcitrans (Diptera: Muscidae)Glen A Scoles
USDA ARS, Animal Disease Research Unit, Washington State University, Pullman, WA 99164, USA
J Med Entomol 42:668-75. 2005....
- Anaplasma phagocytophilum - the most widespread tick-borne infection in animals in EuropeS Stuen
Department of Production Animal Clinical Sciences, Norwegian School of Veterinary Science, Sandnes, Norway
Vet Res Commun 31:79-84. 2007..Based on the 16S rRNA gene sequences several variants exist. Different variants may exist within the same herd and even simultaneously in the same animal. Variants may behave differently and interact in the mammalian host...
- CXCR2 blockade influences Anaplasma phagocytophilum propagation but not histopathology in the mouse model of human granulocytic anaplasmosisDiana G Scorpio
Department of Comparative Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Clin Diagn Lab Immunol 11:963-8. 2004..phagocytophilum is an obligate intracellular bacterium that infects neutrophils and causes human granulocytic anaplasmosis. Infection induces neutrophil secretion of interleukin-8 or murine homologs and perpetuates infection by ..
- Epidemiology of human ehrlichiosis and anaplasmosis in the United States, 2001-2002Linda J Demma
Viral and Rickettsial Zoonoses Branch and Office of the Director, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 73:400-9. 2005..through 2002, 1,176 cases of the tick-borne diseases human monocytic ehrlichiosis (HME) and human granulocytic anaplasmosis (HGA) were reported to the Centers for Disease Control and Prevention (CDC) by 32 states through the National ..
- Temporal patterns of tick-borne granulocytic anaplasmosis in CaliforniaDaniel Rejmanek
School of Veterinary Medicine, Dept of Medicine and Epidemiology, University of California, Davis, CA 95616, USA
Ticks Tick Borne Dis 2:81-7. 2011Granulocytic anaplasmosis (GA) is a tick-borne emerging infectious disease caused by the bacterium Anaplasma phagocytophilum. From fall 2005 to spring 2007, A...
- Epidemiology of bovine tick-borne diseases in southern ItalyGiuseppe Cringoli
Dipartimento di Patologia e Sanita Animale, Universita degli Studi di Napoli Federico II, Italy
Vet Res 33:421-8. 2002..6) and Haemaphysalis punctata (8.4). The results showed that B. bigemina, A. marginale and their potential vectors are common in the area examined and indicated that there is a risk for animals imported from tick-borne disease-free areas...
- Induced immune response of DNA vaccine encoding an association MSP1a, MSP1b, and MSP5 antigens of Anaplasma marginaleFlora S Kano
Protozoology Laboratory, Departamento de Medicina Veterinaria Preventiva, CCA, Universidade de Londrina UEL, Londrina, Parana state, Brazil
Vaccine 26:3522-7. 2008..proteins of Anaplasma marginale have been the focus of research to obtain an improved vaccine against bovine anaplasmosis. We evaluated the capacity of the recombinant plasmids pcDNA-msp1alpha, pcDNA-msp1beta, and pcDNA-mp5 to ..
- Investigation of anaplasmosis in Yiyuan County, Shandong Province, ChinaLijuan Zhang
Department of Rickettsiology and Anaplasmosis, National Institute of Communicable Disease Control and Prevention, China CDC, Beijing 102206, China
Asian Pac J Trop Med 4:568-72. 2011To investigate the situation of anaplasmosis in Yiyuan county, Shandong Province.
- Fatal bovine anaplasmosis in a herd with new genotypes of Anaplasma marginale, Anaplasma ovis and concurrent haemoplasmosisS Hornok
Department of Parasitology and Zoology, Szent Istvan University, Budapest, Hungary
Res Vet Sci 92:30-5. 2012Haematological and molecular analysis of blood samples was carried out during an outbreak of bovine anaplasmosis in Hungary. Acute disease was observed in five animals, two of which died...
- Etiological [corrected] agents of rickettsiosis and anaplasmosis in ticks collected in Emilia-Romagna region (Italy) during 2008 and 2009Giulia Maioli
Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna, Sezione di Reggio Emilia, via Pitagora n 2, 42100 Reggio Emilia, Italy
Exp Appl Acarol 57:199-208. 2012..5 and 1.5%, respectively). Our results highlight that that ticks present in wild areas, widely exploited for recreation and hunting in Emilia-Romagna, represent a risk for the transmission of spotted fevers and anaplasmosis to humans.
- First case of Anaplasma platys infection in a dog from CroatiaViktor Dyachenko
Institute for Infectious Diseases and Zoonoses, Department for Veterinary Sciences, Faculty for Veterinary Medicine, LMU Munich, Veterinarstrasse 13, 80539 Munich, Germany
Parasit Vectors 5:49. 2012..Diagnostic tests were performed to identify infections caused by Anaplasma spp., Ehrlichia spp., Hepatozoon canis, Babesia spp., Leishmania spp., Borrelia burgdorferi and/or Dirofilaria immitis...
- Anaplasmosis in two dogs in France and molecular and phylogenetic characterization of Anaplasma phagocytophilumMargarida Canelas Domingos
Laboratoire Vebiotel, Arcueil, France
Vet Clin Pathol 40:215-21. 2011..phagocytophilum infecting people and animals. Three isolates of A. phagocytophilum, 1 from Spain (cow) and 2 from Norway (sheep and deer), were external to the European and American clades...
- Experimental infection of white-tailed deer with Anaplasma phagocytophilum, etiologic agent of human granulocytic anaplasmosisCynthia M Tate
Southeastern Cooperative Wildlife Disease Study, Wildlife Health Building, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602 7393
J Clin Microbiol 43:3595-601. 2005..However, the susceptibility and immunologic response of WTD to A. phagocytophilum render them suitable candidates as natural sentinels for this zoonotic tick-borne organism...
- Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cellsJose De La Fuente
Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, 250 McElroy Hall, 74078 2007, Stillwater, OK, USA
Vet Microbiol 91:265-83. 2003..These studies demonstrated that the tandemly repeated region of the protein mediates the adhesive function of MSP1a...
- Epidemiology of bovine anaplasmosis in dairy herds from Costa RicaJ B Oliveira
Catedra de Parasitologia, Departamento de Biologia, Universidade Federal Rural de Pernambuco UFRPE, Dom Manoel de Medeiros SN, Recife, CEP 52171 900, Pernambuco, Brazil
Vet Parasitol 177:359-65. 2011Bovine anaplasmosis is endemic and occurs in almost all areas of livestock production of Costa Rica...
- Antibody against an Anaplasma marginale MSP5 epitope common to tick and erythrocyte stages identifies persistently infected cattleD Knowles
Animal Disease Research Unit, USDA Agricultural Research Service, Pullman, Washington, USA
J Clin Microbiol 34:2225-30. 1996..was established by using 261 serum samples from cattle in the regions of Hawaii and Northern Ontario where anaplasmosis is not endemic and from cattle proven by splenectomy or subinoculation of whole blood into susceptible ..
- Anaplasmosis control and diagnosis in South AfricaD T De Wall
Parasitology Division, Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort 0110, South Africa
Ann N Y Acad Sci 916:474-83. 2000b>Anaplasmosis is widespread in South Africa with more than 99% of the total cattle population at risk. Five tick species have been experimentally shown to be capable of transmitting Anaplasma in South Africa...
- Ehrlichia platys (Anaplasma platys) in dogs from Maracaibo, Venezuela: an ultrastructural study of experimental and natural infectionsC Arraga-Alvarado
Unidad de Investigacioned Clínicas Facultad de Ciencias Veterinarias, Universidad del Zulia, Maracaibo, Venezuela
Vet Pathol 40:149-56. 2003..Our results indicate that distinct ultrastructural characteristics are associated with different stages of A. platys development and may differ among A. platys strains...
- Genetic variants of Anaplasma phagocytophilum from 14 equine granulocytic anaplasmosis casesCornelia Silaghi
Comparative Tropical Medicine and Parasitology, Faculty of Veterinary Medicine, Ludwig Maximilians Universitat, Leopoldstr, 5, 80802 Munich, Germany
Parasit Vectors 4:161. 2011Equine Granulocytic Anaplasmosis (EGA) is caused by Anaplasma phagocytophilum, a tick-transmitted, obligate intracellular bacterium. In Europe, it is transmitted by Ixodes ricinus. A large number of genetic variants of A...
- Agents of human anaplasmosis and Lyme disease at Camp Ripley, MinnesotaRUSSELL C JOHNSON
University of Minnesota, Department of Microbiology, Minneapolis, Minnesota 55455, USA
Vector Borne Zoonotic Dis 11:1529-34. 2011..Antibodies to Bb were detected in >80% of the deer, but Bb DNA was only detected in 1.5% of blood specimens...
- Molecular epidemiology of human and bovine anaplasmosis in southern EuropeVictoria Naranjo
Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
Ann N Y Acad Sci 1078:95-9. 2006..The presence of concurrent infections in cattle and deer suggests that these pathogens may multiply in the same reservoir host and illustrates the complexity of the epidemiology of bovine and human anaplasmosis in this region.
- The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of AmericaGary P Wormser
Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
Clin Infect Dis 43:1089-134. 2006Evidence-based guidelines for the management of patients with Lyme disease, human granulocytic anaplasmosis (formerly known as human granulocytic ehrlichiosis), and babesiosis were prepared by an expert panel of the Infectious Diseases ..
- Development of enzyme-linked immunosorbent assays based on recombinant MSP1a and MSP2 of Anaplasma marginaleFlábio R Araújo
Embrapa Gado de Corte, Rodovia BR 262, 79002 970 Campo Grande, MS, Brazil
Mem Inst Oswaldo Cruz 100:765-9. 2005..89. The similar performances of the ELISAs suggest that both tests can be used in epidemiological surveys for detection of antibodies to A. marginale in cattle...
- Immunity following use of Australian tick fever vaccine: a review of the evidenceR E Bock
Tick Fever Research Centre, Animal and Plant Health Service, Queensland Department of Primary Industries, Wacol
Aust Vet J 79:832-9. 2001..To review the evidence available on the degree and duration of immunity provided by Australian tick fever vaccines against Babesia bovis, B. bigemina and Anaplasma marginale infections in Australia and overseas...
- Immunogenicity of Anaplasma marginale type IV secretion system proteins in a protective outer membrane vaccineJob E Lopez
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
Infect Immun 75:2333-42. 2007..marginale and related pathogens...
- Anaplasmosis control. Past, present, and futureK M Kocan
Department of Anatomy, Pathology and Pharmacology, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, USA
Ann N Y Acad Sci 916:501-9. 2000Control methods for anaplasmosis have not changed markedly during the past 50 years and include arthropod control, chemoprophylaxsis, vaccination, and maintenance of an Anaplasma-free herd...
- Possible differential host tropism in Anaplasma phagocytophilum strains in the Western United StatesJanet Foley
School of Veterinary Medicine, Department of Medicine and Epidemiology, University of California, Davis, Davis California, USA
Ann N Y Acad Sci 1149:94-7. 2008..phagocytophilum strains and further research to understand the host-pathogen interactions that result in differential outcomes in infection...
- Diagnosis of canine vector-borne diseases in young dogs: a longitudinal studyDomenico Otranto
Department of Veterinary Public Health and Animal Sciences, Faculty of Veterinary Medicine, Valenzano, Bari, Italy
J Clin Microbiol 48:3316-24. 2010....
- Differential adhesion of major surface proteins 1a and 1b of the ehrlichial cattle pathogen Anaplasma marginale to bovine erythrocytes and tick cellsJ de la Fuente
Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
Int J Parasitol 31:145-53. 2001..marginale adhesin for both bovine erythrocytes and tick cells while MSP1b is an adhesin only for bovine erythrocytes. The role of the MSP1 complex, therefore, appears to vary among vertebrate and invertebrate hosts...
- Detection of Anaplasma platys and Babesia canis vogeli and their impact on platelet numbers in free-roaming dogs associated with remote Aboriginal communities in AustraliaG K Brown
Discipline of Biological Sciences, School of Environmental and Life Sciences, University of Newcastle, Callaghan NSW 2308, Australia
Aust Vet J 84:321-5. 2006....
- ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infectionJoao H F Pedra
Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
J Immunol 179:4783-91. 2007..phagocytophilum. Taken together, our data demonstrate that ASC and caspase-1 are critical for IFN-gamma-mediated control of A. phagocytophilum infection...
- Molecular evidence for persistence of Anaplasma phagocytophilum in the absence of clinical abnormalities in horses after recovery from acute experimental infectionP Franzen
Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden
J Vet Intern Med 23:636-42. 2009..Anaplasma phagocytophilum infects several mammalian species, and can persist in sheep, dogs, and calves. However, whether this organism persists in horses or induces long-term clinical abnormalities is not known...
- Identification of Anaplasma marginale outer membrane protein antigens conserved between A. marginale sensu stricto strains and the live A. marginale subsp. centrale vaccineJoseph T Agnes
Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
Infect Immun 79:1311-8. 2011..marginale and provides clear direction for development of a safer, more effective vaccine...
- Expression of Anaplasma marginale major surface protein 2 operon-associated proteins during mammalian and arthropod infectionCHRISTIANE V LOHR
Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164 7040, USA
Infect Immun 70:6005-12. 2002....
- Clinical diagnosis and treatment of human granulocytotropic anaplasmosisJohan S Bakken
St Luke s Infectious Disease Associates, 1001 East First Street, Suite L201, Duluth, Minnesota 55802, USA
Ann N Y Acad Sci 1078:236-47. 2006..of humans previously known as human granulocytotropic ehrlichiosis (HGE) and now called human granulocytotropic anaplasmosis (HGA)...
- A sero-epidemiological survey of blood parasites in cattle in the north-eastern Free State, South AfricaM S Mtshali
Parasitology Research Programme, Qwa Qwa Campus, University of the Free State, Private Bag X 13, Phuthaditjhaba, 9866 South Africa
Onderstepoort J Vet Res 71:67-75. 2004..The presence of R. evertsi evertsi throughout the year without any or with small fluctuations in winter months was observed, with a peak from February to May...
- CD4(+) T-lymphocyte and immunoglobulin G2 responses in calves immunized with Anaplasma marginale outer membranes and protected against homologous challengeW C Brown
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164, USA
Infect Immun 66:5406-13. 1998....
- Detection and quantification of Anaplasma marginale DNA in blood samples of cattle by real-time PCRG Carelli
Department of Animal Health and Well Being, Faculty of Veterinary Medicine of Bari, Strada per Casamassima Km 3, 70010 Valenzano, Bari, Italy
Vet Microbiol 124:107-14. 2007..marginale DNA in bovine blood, that is essential to support the clinical diagnosis, to assess the carrier status of the animals and to evaluate the efficacy of vaccines and antirickettsial drugs...
- Serologic and molecular characterization of Anaplasma species infection in farm animals and ticks from SicilyJose De La Fuente
Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, 250 McElory Hall, Stillwater, OK 74078, USA
Vet Parasitol 133:357-62. 2005..Definition of the diversity of Anaplasma spp. in Sicily reported, herein is fundamental to development of control strategies for A. marginale, A. ovis and A. phagocytophilum in Sicily...
- First serological and molecular evidence on the endemicity of Anaplasma ovis and A. marginale in HungarySándor Hornok
Department of Parasitology and Zoology, Faculty of Veterinary Science, Szent Istvan University, Istvan u 2, Budapest, Hungary
Vet Microbiol 122:316-22. 2007..Haemoglobinuria, an unusual clinical sign for anaplasmosis might have been a consequence of transient intravascular haemolysis facilitated by selenium deficiency in ..
- A review of bovine anaplasmosisP Aubry
Canadian Food Inspection Agency, Ottawa, ON, Canada
Transbound Emerg Dis 58:1-30. 2011Bovine anaplasmosis, caused by Anaplasma marginale, is an infectious but non-contagious disease...
- Conservation of a gene conversion mechanism in two distantly related paralogues of Anaplasma marginalePatrick F M Meeus
Department of Pathobiology, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, FL 32611 0880, USA
Mol Microbiol 47:633-43. 2003Anaplasmataceae, the causative agents of anaplasmosis and ehrlichiosis, persist in the bloodstream of their mammalian hosts, allowing acquisition and transmission by tick vectors...
- First report of bovine anaplasmosis caused by Anaplasma centrale in EuropeGrazia Carelli
Department of Animal Health and Well Being, Faculty of Veterinary Medicine of Bari, Valenzano Bari, Italy
Ann N Y Acad Sci 1149:107-10. 2008..Herein we report a clinical case of bovine anaplasmosis associated with A...
- Molecular detection of Anaplasma platys in dogs using polymerase chain reaction and reverse line blot hybridizationOlivier A E Sparagano
School of Agriculture, Food and Rural Development, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
J Vet Diagn Invest 15:527-34. 2003..platys. Sequences obtained from some samples and compared with those within the GenBank also confirmed the presence of A. platys...
- Concurrent infections with vector-borne pathogens associated with fatal hemolytic anemia in a cattle herd in SwitzerlandRegina Hofmann-Lehmann
Clinical Laboratory, University of Zurich, Switzerland
J Clin Microbiol 42:3775-80. 2004Bovine anaplasmosis is a vector-borne disease that results in substantial economic losses in other parts of the world but so far not in northern Europe...
- Differences and similarities between culture-confirmed human granulocytic anaplasmosis and early lyme diseaseGary P Wormser
Department of Medicine, Division of Infectious Diseases, New York Medical College, Valhalla, New York, USA
J Clin Microbiol 51:954-8. 2013..of certain Ixodes ticks, which can also transmit Anaplasma phagocytophilum, the cause of human granulocytic anaplasmosis (HGA). Although culture can be used to identify patients infected with A...
- Clinical, serological, and molecular evidence of ehrlichiosis and anaplasmosis in dogs in TunisiaY M'Ghirbi
Service d Entomologie Médicale, Institut Pasteur de Tunis, 1002 Tunis, Tunisia
Parasitol Res 104:767-74. 2009..phagocytophilum and Ehrlichia sp. RLB findings were confirmed by sequencing; BLAST search against GenBank revealed high similarity of the sequence of Ehrlichia sp. PCR/RLB amplicons with Anaplasma platys 16S rRNA partial sequence...
- Human granulocytic anaplasmosis and macrophage activationJ Stephen Dumler
Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Clin Infect Dis 45:199-204. 2007Patients with human granulocytic anaplasmosis present with fever, thrombocytopenia, leukopenia, and an elevated aspartate transaminase level. Clinical and histopathologic features of severe disease suggest macrophage activation...
- Multitarget test for emerging Lyme disease and anaplasmosis in a serosurvey of dogs, Maine, USAPeter W Rand
Maine Medical Center Research Institute, South Portland, Maine 04106, USA
Emerg Infect Dis 17:899-902. 2011..An extension of exposure to Borrelia burgdorferi to the northern border and local transmission of Anaplasma phagocytophilum throughout southern areas was found...
- Genetic characterization of Anaplasma (Ehrlichia) platys in dogs in SpainE Aguirre
Departamento de Medicina y Cirugia Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
J Vet Med B Infect Dis Vet Public Health 53:197-200. 2006..These data confirm the presence of A. platys in a dog showing clinical signs compatible with ehrlichiosis in Spain...
- First case of human granulocytic anaplasmosis from SlovakiaMaria Novakova
Parasitological Institute of the Slovak Academy of Sciences, Kosice, Slovakia
Ann Agric Environ Med 17:173-5. 2010In order to evaluate the potential risks of human granulocytic anaplasmosis in Slovakia, blood and serum samples of hunters and foresters from the northern parth of Slovakia were tested...
- Anaplasmosis: focusing on host-vector-pathogen interactions for vaccine developmentJose De La Fuente
Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA
Ann N Y Acad Sci 1078:416-23. 2006Anaplasma marginale and A. phagocytophylum are intracellular rickettsiae that cause bovine anaplasmosis and human granulocytic anaplasmosis, respectively...
- An assessment of whole blood and fractions by nested PCR as a DNA source for diagnosing canine ehrlichiosis and anaplasmosisTereza Emmanuelle de Farias Rotondano
Departamento de Ciencias Biologicas, Universidade Federal de Pernambuco, Avenue Professor Moraes Rego, S N, Cidade Universitaria, 50 670 901 Recife, PE, Brazil
ScientificWorldJournal 2012:605743. 2012Ehrlichiosis and anaplasmosis are tick-borne diseases. Ehrlichia canis and Anaplasma platys infect mainly white cells and platelets, respectively...
- Diagnostic accuracy of methods for detecting Anaplasma marginale infection in lactating dairy cattle of Puerto RicoGeoffrey T Fosgate
Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, 0110, South Africa
J Vet Diagn Invest 22:192-9. 2010Bovine anaplasmosis (BA) is a hemoparasitic disease of great importance in cattle within the tropical and subtropical regions of the world...
- [Ehrlichiosis and human anaplasmosis]Jose Antonio Oteo
Area de Enfermedades Infecciosas, Complejo Hospitalario San Millán San Pedro de La Rioja, Logrono, Espana
Enferm Infecc Microbiol Clin 23:375-80. 2005Human ehrlichiosis and anaplasmosis are acute febrile tick-borne diseases caused by various species of the genera Ehrlichia and Anaplasma (Anaplasmataceae)...
- Prevalence of Anaplasma marginale in different tick species from Ngorongoro Crater, TanzaniaRobert D Fyumagwa
Tanzania Wildlife Research Institute TAWIRI Wildlife Veterinary Programme, P O Box 661, Arusha, Tanzania
Vet Parasitol 161:154-7. 2009..decoloratus have previously not been described to transmit A. marginale. High diversity of tick species detected with A. marginale in Ngorongoro Crater is likely to increase a risk to susceptible animals of contracting the infection...
- In vivo endothelial cell infection by Anaplasma marginaleA D Carreño
Department of Pathobiology, Auburn University, AL 36849 5519, USA
Vet Pathol 44:116-8. 2007..The results indicate that A marginale infection includes endothelial cells and has implications for both pathogenesis and immune mechanisms...
- Clinical findings and diagnosis in human granulocytic anaplasmosis: a case series from MassachusettsAna A Weil
Department of Medicine, Massachusetts General Hospital, 15 Parkman St, Boston, MA 02114, USA
Mayo Clin Proc 87:233-9. 2012To describe clinical findings and the use of a tick-associated pathogen panel in a series of patients with human granulocytic anaplasmosis (HGA) at a suburban Boston hospital.
- Adaptations of the tick-borne pathogen, Anaplasma marginale, for survival in cattle and ticksKatherine M Kocan
Department of Veterinary Pathobiology, 250 McElroy Hall, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078 2007, USA
Exp Appl Acarol 28:9-25. 2002..Infection and development of A. marginale in cattle and tick cells appears to differ and to be mediated by several surface proteins encoded from the small genome...
- Anaplasma phagocytophilum in Ixodes ricinus ticks and human granulocytic anaplasmosis seroprevalence among forestry rangers in Białystok regionA Grzeszczuk
Department of Infectious Diseases, Medical University of Białystok, Poland
Adv Med Sci 51:283-6. 2006Human granulocytic anaplasmosis, former ehrlichiosis, is a tick-borne zoonosis of increasing recognition...
- Structural basis for segmental gene conversion in generation of Anaplasma marginale outer membrane protein variantsJames E Futse
Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
Mol Microbiol 57:212-21. 2005..Importantly, the anchoring model, which can account for more variants than a strict segmental sequence identity mechanism, is consistent with the number of msp2 variants predicted and empirically identified during persistent infection...
- Failure to demonstrate Babesia, Anaplasma or Ehrlichia in thrombocytopenic dogs from St KittsPatrick J Kelly
Ross University School of Veterinary Medicine, PO Box 334, Basseterre, St Kitts, West Indies
J Infect Dev Ctries 3:561-3. 2009..Thrombocytopenia is common in dogs on St Kitts but there is no data on the possible etiological role played by infections with Anaplasma, Babesia and Ehrlichia, other than E. canis, which are known to occur in the Caribbean...
- Human anaplasmosis: the first Spanish case confirmed by PCRJ C Garcia
Servicio de Medicina Interna, F P Hospital Do Salnés, C Estromil Ande Rubians, 36600 Vilagarcía de Arousa Pontevedra, Spain
Ann N Y Acad Sci 1078:545-7. 2006We report a case of human anaplasmosis (HA) fulfilling the confirmation criteria: epidemiologic data and clinical picture compatible with HA; presence of a morulae within polymorphonuclear leukocyte; and positive PCR assay for Anaplasma ..
- Serologic evidence of equine granulocytic anaplasmosis in horses from central West BrazilCarlos Augusto Salvagni
Departamento de Patologia Veterinária, FCAV UNESP, Universidade Estadual Paulista UNESP
Rev Bras Parasitol Vet 19:135-40. 2010..Equine Granulocytic Anaplasmosis - EGA (formerly Equine Granulocytic Ehrlichiosis, EGE) is a seasonal disease, normally self-limited in horses...
- Occurrence of concurrent trypanosomosis, theileriosis, anaplasmosis and helminthosis in Friesian, Zebu and Sahiwal cattle in UgandaJ W Magona
Livestock Health Research Institute, Tororo, Uganda
Onderstepoort J Vet Res 69:133-40. 2002..Persistent mortality of cattle on these farms could have been due to either single or mixed parasitic infections probably exacerbated by malnutrition...
- The immunization-induced antibody response to the Anaplasma marginale major surface protein 2 and its association with protective immunitySusan M Noh
Animal Disease Research Unit, Agricultural Research Service, U S Department of Agriculture, Pullman, WA 99164 7030, USA
Vaccine 28:3741-7. 2010....
- Immune response of BALB/c mouse immunized with recombinant MSPs proteins of Anaplasma marginale binding to immunostimulant complex (ISCOM)Paula M Kawasaki
Universidade Estadual de Londrina, Departamento Medicina Veterinária Preventiva, CCA, Campus Universitario, Caixa Postal 6001, 86051 970 Londrina, PR, Brazil
Res Vet Sci 83:347-54. 2007b>Anaplasmosis, caused by Anaplasma marginale, results in significant economic losses of cattle in tropical and subtropical regions worldwide...
- Tick- and flea-borne rickettsial emerging zoonosesPhilippe Parola
Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 5, France
Vet Res 36:469-92. 2005..Ehrlichia chaffeensis, the agent of human monocytic ehrlichiosis, Anaplasma phagocytophilum, the agent of human anaplasmosis (formerly known as "human granulocytic ehrlichiosis agent", E. equi and E...
- Amplification of 16S rRNA genes of Anaplasma species in China for phylogenetic analysisZhijie Liu
Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 11, Lanzhou, Gansu 730 046, China
Vet Microbiol 107:145-8. 2005..ovis cluster, while the A. marginale in China was separated into an A. marginale cluster (see Fig. 1). This analysis demonstrated that there are at least two different Anaplasma species widespread among ruminants in North China...
- Genetic diversity of major surface protein 1a of Anaplasma marginale in beef cattleT Molad
Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
Vet Microbiol 136:54-60. 2009..study was aimed to demonstrate genotypic diversity of Anaplama marginale in infected beef herds grazing within anaplasmosis endemic regions...
- [Anaplasmosis in a Swiss dairy farm: an epidemiological outbreak investigation]F Brulisauer
Bundesamt für Veterinärwesen, Bern
Schweiz Arch Tierheilkd 146:451-9. 2004In summer of 2002, a case of severe clinical bovine anaplasmosis caused great losses in a dairy farm of an animal trader in Grisons...
- Anaplasma marginale Yucatan (Mexico) Strain. Assessment of low virulence and potential use as a live vaccineSergio D Rodríguez Camarillo
Centro de Investigaciones Disciplinarias, en Parasitología Veterinaria, Instituto Nacional de Investigaciones Forestales, Agricolas y Pecuarias, Secretaría de Agricultura, Ganaderia, Desarrollo Rural, Pesca y Alimentació, Jiutepec, Morelos, Mexcio
Ann N Y Acad Sci 1149:98-102. 2008..The A. marginale vaccine strains used for the immunization studies had MSP1a variable regions that were different from those used for the challenge exposure...
- Concomitant infection of cattle with the vaccine strain Anaplasma marginale ss centrale and field strains of A. marginaleVarda Shkap
Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
Vet Microbiol 130:277-84. 2008Bovine anaplasmosis, caused by Anaplasma marginale, the intraerythrocytic rickettsia, is controlled by vaccination with live Anaplasma marginale ss centrale (A. centrale), a subspecies of relatively low pathogenicity...
- Molecular epidemiology of bovine anaplasmosis with a particular focus in MexicoSergio D Rodríguez
Departamento de Infectómica y Patogénesis Molecular, Centro de Investigacion y de Estudios Avanzados del IPN, Mexico DF 07360, Mexico
Infect Genet Evol 9:1092-101. 2009Bovine anaplasmosis, caused by the rickettsia Anaplasma marginale, has a worldwide distribution and is the cause of great economic losses in developing countries where it is highly endemic...
- Composition of the surface proteome of Anaplasma marginale and its role in protective immunity induced by outer membrane immunizationSusan M Noh
Animal Disease Research Unit, Agriculture Research Service, U S Department of Agriculture, Pullman, WA 99164 7030, USA
Infect Immun 76:2219-26. 2008..Furthermore, the data support that remodeling of the surface proteome accompanies the transition between mammalian and arthropod hosts and identify novel targets for blocking transmission...
- Potential vertebrate reservoir hosts and invertebrate vectors of Anaplasma marginale and A. phagocytophilum in central SpainJose De La Fuente
Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ciudad Real, Spain
Vector Borne Zoonotic Dis 5:390-401. 2005..The type species, A. marginale, causes bovine anaplasmosis and only infects ticks and ruminants. A...
- Molecular detection of Anaplasma platys and Ehrlichia canis in dogs from the North of PortugalLuis Cardoso
Department of Veterinary Sciences and CECAV, University of Tras os Montes e Alto Douro, P O Box 1013, 5001 801 Vila Real, Portugal
Vet J 183:232-3. 2010..One of these latter animals was co-infected with Babesia canis subspecies vogeli. This is the first report of the genetic characterisation of both A. platys and E. canis in naturally infected dogs from the North of Portugal...
- Molecular characterization of Thai Ehrlichia canis and Anaplasma platys strains detected in dogsDanai Pinyoowong
Department of Genetics, Faculty of Science, Kasetsart University, Thailand
Infect Genet Evol 8:433-8. 2008..platys from Thailand. To our knowledge this report represents the first molecular characterization of the nearly complete 16S rRNA gene from E. canis in dogs from Thailand...
- Studies on correlations among parasitaemia and some hemolytic indices in two tropical diseases (theileriosis and anaplasmosis) in Fars province of IranS Nazifi
Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, P O Box 1731, Shiraz 71345, Iran
Trop Anim Health Prod 40:47-53. 2008..increased the anaemia, MCF and LDH activity increased and SOD activity decreased at any parasitaemia, but in anaplasmosis the anaemia, MCF and LDH activity increased at any parasitaemia but SOD activity decreased only in early but ..
- Selection for simple major surface protein 2 variants during Anaplasma marginale transmission to immunologically naïve animalsGuy H Palmer
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
Infect Immun 75:1502-6. 2007..However, these mosaics have a selective advantage only in the presence of adaptive immunity and are rapidly replaced by simple variants following transmission...
- Reduced weight gain due to subclinical Anaplasma phagocytophilum (formerly Ehrlichia phagocytophila) infectionSnorre Stuen
Norwegian School of Veterinary Science, Department of Sheep and Goat Research, Kyrkjevegen 332 334, N 4325 Sandnes, Norway
Exp Appl Acarol 28:209-15. 2002..8 kg compared with the uninfected lambs. The present study indicates that A. phagocytophilum infection may be widespread and contribute to considerable productivity losses even on pastures with no apparent tick infestation...
- Human anaplasmosis presenting as atypical pneumonitis in FranceV Remy
Service de Maladies Infectieuses et Pathologies Tropicales, Hopitaux Universitaires de Strasbourg, Strasbourg, France
Clin Infect Dis 37:846-8. 2003Human anaplasmosis is a febrile illness caused by Anaplasma phagocytophilum, an intracellular bacterium transmitted by Ixodes ticks in the United States and Europe...
- Systematics of medically important Dermacentor tick vectorsDmitry A Apanaskevich; Fiscal Year: 2011..conori causing Boutenneuse fever;Francisella tularensis causing tularemia in humans;and pathogens causing anaplasmosis, babesioses, and theileriosis in animals. These species also transmit several viruses that cause human diseases...
- Tick-Mammal Interface of Human Granulocytic AnaplasmosisULRIKE GERTRUD MUNDERLOH; Fiscal Year: 2013DESCRIPTION (provided by applicant): Human granulocytic anaplasmosis (HGA) is a severe illness with a fatality rate of <5% that, like spotted fever, is caused by tick-borne intracellular bacteria, presenting a highly relevant, ..
- Symbiotic Rickettsia Species as a Model System for the Study of Folate BiosynthesJianmin Zhong; Fiscal Year: 2012..PUBLIC HEALTH RELEVANCE: Lyme borreliosis and anaplasmosis are the most common tick-borne diseases in the United States, and prevention of these diseases has become the ..
- Tick feeding regulation by orthologous tick saliva serine protease inhibitorsAlbert Mulenga; Fiscal Year: 2013..in the emergence of major human tick borne diseases (TBD) in the United States, Lyme disease, human anaplasmosis, babesiosis and ehrlichiosis and the southern tick-associated rash illness (STARI) has been recognized...
- TYPE IV SECRETION &SIGNAL TRANSDUCTION IN EHRLICHIOSISYasuko Rikihisa; Fiscal Year: 2013..and Ehrlichia chaffeensis cause emerging potentially fatal infectious diseases human granulocytic anaplasmosis (HGA) and human monocytic ehrlichiosis (HME), respectively...
- Identification of bacterial genes required for transmission of tick-borne pathogeSusan M Noh; Fiscal Year: 2012DESCRIPTION (provided by applicant): Tick-borne diseases, including anaplasmosis, ehrlichiosis, and several rickettsial diseases, remain poorly controlled amid increasing incidence...
- Interactions Between Anaplasma Phagocytophilum and Ixodes ScapularisErol Fikrig; Fiscal Year: 2013DESCRIPTION (provided by applicant): Human granulocytic anaplasmosis is the second most common tick-borne disease in the United States...
- Anaplasma regulation of host granulocyte functionJohn Stephen Dumler; Fiscal Year: 2013DESCRIPTION (provided by applicant): Human granulocytic anaplasmosis (HGA) is an emerging tick-borne disease caused by Anaplasma phagocytophilum, an obligate intracellular bacterium of neutrophils. A...
- Human pathogenic bacterium induces actin phosphorylation to selectively regulateHameeda Sultana; Fiscal Year: 2012..Using Ixodes scapularis ticks and Anaplasma phagocytophilum (the agent of human granulocytic anaplasmosis) as an infection model, I provide evidence for the first time to show how an obligate intracellular bacterium ..
- Overwintering mortality of nymphal Ixodes scapularis, Lyme disease vector, in a cRICHARD S contact OSTFELD; Fiscal Year: 2010..vectors the agents of three emerging infectious diseases in North America: Lyme disease, human granulocytic anaplasmosis, and babesiosis...
- Characterization of an Anaplasma phagocytophilum protein interfering with eukaryoSukanya Narasimhan; Fiscal Year: 2010DESCRIPTION (provided by applicant): Anaplasma phagocytophilum, the causative agent of human Anaplasmosis, is a tick-borne pathogen with an unusual tropism for the front-line immune defense cells (neutrophils)...
- Dynamics of neutrophil trafficking in Granulocytic AnaplasmosisJENNIFER LYNN JOHNS; Fiscal Year: 2013..phagocytophilum is a tick-borne obligate intracellular bacterial pathogen and the agent of granulocytic anaplasmosis in humans and animals. A...
- Dynamics of neutrophil trafficking in Granulocytic AnaplasmosisJENNIFER LYNN JOHNS; Fiscal Year: 2011..phagocytophilum is a tick-borne obligate intracellular bacterial pathogen and the agent of granulocytic anaplasmosis in humans and animals. A...
- Vector and Host Contributions to the Regulation of E. chaffeensis Gene ExpressionRoman R Ganta; Fiscal Year: 2012..These illnesses include human monocytic ehrlichiosis, human granulocytic ehrlichiosis and human granulocytic anaplasmosis which are caused by Ehrlichia chaffeensis, E. ewingii and Anaplasma phagocytophilum, respectively...
- LYMPHOCYTE-MEDIATED IMMUNITY TO ANAPLASMA MARGINALEReginald Valdez; Fiscal Year: 1999..There was some uncertainty as to the extent of the problem of acute anaplasmosis infection in cattle and how the research findings might impact the field. Since Dr...
- Keys to prevent cholesterol robbery and infection by intracellular bacteriaYasuko Rikihisa; Fiscal Year: 2013DESCRIPTION (provided by applicant): Human granulocytic anaplasmosis (HGA) is an emerging zoonosis, and one of the most prevalent life- threatening tick-borneillnesses in North America...
- 13th International Conference on Lyme Borreliosis and Other Tick-borne DiseasesLinden T Hu; Fiscal Year: 2013..The diseases included in this conference are Lyme borreliosis, babesiosis, human granulocytic anaplasmosis (ehrlichiosis) and tick-borne encephalitis...
- Anaplasma phagocytophilum induce Ixodes scapularis antifreeze glycoprotein gene eGirish Neelakanta; Fiscal Year: 2012..the Northeast and Upper Midwest parts of United States, and transmit various human pathogens that include human anaplasmosis agent Anaplasma phagocytophilum. My preliminary data show that the presence of A...
- The roles of Anaplasma phagocytophilum surface proteins in cellular invasionJason A Carlyon; Fiscal Year: 2013..neutrophils and endothelial cells to cause the emerging and potentially fatal infection, human granulocytic anaplasmosis (HGA). A...
- The roles of Anaplasma phagocytophilum surface proteins in cellular invasionJason A Carlyon; Fiscal Year: 2012..neutrophils and endothelial cells to cause the emerging and potentially fatal infection, human granulocytic anaplasmosis (HGA). A...
- Ehrlichiacidal Mechanism in LeukocytesYasuko Rikihisa; Fiscal Year: 2011Human granulocytic anaplasmosis (HGA) is one of most prevalent life-threatening tick-borne zoonoses in North America. This disease is caused by Anaplasma phagocytophilum, a Gram-negative obligatory intracellular bacterium. A...
- A. phagocytophilum and NF-kB signalingJohn Stephen Dumler; Fiscal Year: 2010Human granulocytic anaplasmosis (HGA) is tick-borne disease caused by Anaplasma phagocytophilum, an obligate intracellular bacterium of neutrophils. A...
- Landscape Ecology and Mapping of Ehrlichial PathogensMICHAEL WIMBERLY; Fiscal Year: 2006..diseases are human monocytotropic ehrlichiosis (HME), caused by Ehrlichia chaffeensis; and human granulocytic anaplasmosis (HGA) caused by Anaplasma phagocytophilum...
- Anaplasma - B. burgorferi/endothelijm interactionsDENNIS GRAB; Fiscal Year: 2006..Human granulocytic anaplasmosis (HGA) is caused by Anaplasma phagocytophilum, a rickettsia of neutrophils that is also transmitted by the deer ..
- MOLECULAR MECHANISMS OF MSP2 VARIATION IN RICKETTSIAEAnthony Barbet; Fiscal Year: 2007..of the mechanisms of pathogenesis of tick- borne rickettsial pathogens that cause ehrlichiosis and anaplasmosis of humans and animals. These pathogens efficiently utilize a small genome (<1...
- A Rickettsial Symbiont Model for the Control of Tick-borne DiseasesJianmin Zhong; Fiscal Year: 2009..Lyme borreliosis and human granulocytic anaplasmosis are severe bacterial diseases that, in California, are vectored primarily by Ixodes pacificus ticks...
- Immunity directed against MSP 2 during anaplasmosisJeffrey Abbott; Fiscal Year: 2004..Levels of rickettsemia during persistent anaplasmosis are approximately two orders of magnitude less than rickettsemia levels during acute infection and do not ..
- Anaplasma marginale genes determining tick transmissionMICHAEL DARK; Fiscal Year: 2007..The genera Anaplasma and Ehriichia, including the organisms responsible for human anaplasmosis and human ehrlichiosis, require an ixodid tick vector for transmission from a mammalian reservoir to a ..
- Virulence and Immunity of Granulocytic EhrlichiaeJOHN DUMLER; Fiscal Year: 2007ABSTRACT Human granulocytic anaplasmosis (HGA) is a tick-borne infection caused by Anaplasma phagocytophilum, an obligate intracellular bacterium of neutrophils...
- Virulence and Immunity of Granulocytic EhrlichiaeJOHN DUMLER; Fiscal Year: 2005..This information will provide the framework for rational design of new therapies aimed at modulating immune mechanisms and design of preventative measures aimed at immunization. ..
- GENE EXPRESSION BY HUMAN GRANULOCYTIC EHRLICHIOSIS AGYasuko Rikihisa; Fiscal Year: 2004..These efforts are expected to reveal an important role for the p44-multigene family in strategies of adaptive surface variation and avoidance of host immune responses. ..
- Ehrilchiacidal Mechanisms In LeukocytesYasuko Rikihisa; Fiscal Year: 2009..The results may point to a potential target for new treatment and prevention of HME and HGE. ..
- ROLES OF EHRLICHIAL OUTER MEMBRANE PROTEIN IN PARASITISMYasuko Rikihisa; Fiscal Year: 2001..Aim 5 addresses hypothesis 3 by examining the effects of immunization with the ehrlichial OMP in a mouse model of human ehrlichiosis. ..
- Comparison of Human Ehrlichiosis Agent GenomesYasuko Rikihisa; Fiscal Year: 2010..chaffeensis virulence determinants and their pathogenic mechanisms. The results may point to potential chemotherapy, chemopreventive and/or vaccine candidates for treatment and prevention of human ehrlichiosis. ..
- Genetic Determinants of Anaplasma TransmissionSUSAN NOH; Fiscal Year: 2004..and animal diseases including human granulocytic ehrlichiosis (HGE), equine ehrlichiosis, and bovine and ovine anaplasmosis. These pathogens are small, Gram-negative, obligately intracellular bacteria that require ixodid ticks for ..
- Antigenic variation in rickettsial transmissionGuy Palmer; Fiscal Year: 2008..This hypothesis will be addressed using comprehensive identification of the variant population in the reservoir host and tick vector and testing whether immune responses against a broad array of variants prevents superinfection. ..
- Topical Antibiotics to Prevent Lyme DiseaseGary Wormser; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Immunopathogenesis of Human Granulocytic AnaplasmosisErol Fikrig; Fiscal Year: 2008Summary/Abstract Human granulocytic anaplasmosis is the second most common tick-borne disease in the United States...
- Granulocytic Ehrlichiosis: Cell-Pathogen InteractionsDori Borjesson; Fiscal Year: 2005..Currently, the candidate is a junior faculty member at a strong research institution with a clear mandate and desire to pursue an independent research program. ..
- PATHOGENESIS OF HUMAN GRANULOCYTIC EHRLICHIOSISUlrike Munderloh; Fiscal Year: 2001....
- Cellular Immunity Against Ehrlichia chaffeensisROMAN GANTA; Fiscal Year: 2002..chaffeensis and other closely related organisms. ..
- Antigenic variation of Anaplasma marginalePATRICK MEEUS; Fiscal Year: 2003..Investigations of bovine anaplasmosis offer a unique opportunity to study the mechanisms of antigenic variation in a natural animal model under ..
- LYME DISEASE IN WESTERN USA: ECOLOGY AND EPIDEMIOLOGYRobert Lane; Fiscal Year: 2008..Development of this risk model, which culminates over 2 decades of intensive study, should contribute significantly to our knowledge of the landscape ecology and epidemiology of LD in this region. ..
- Symposium on the Landscape Ecology of Infectious DiseaseMICHAEL WIMBERLY; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Identifying human genes required by tick-borne pathogensUlrike Munderloh; Fiscal Year: 2007..We anticipate that the interaction of the human host cells with these highly specialized intracellular pathogens will shed light,on the nature of some unidentified human genes. [unreadable] [unreadable] [unreadable]..
- Diagnosis and Pathogenesis of Early Lyme DiseaseAllen Steere; Fiscal Year: 2007..In addition, greater knowledge of spirochetal virulence and host factors associated with severe disease may allow the development of laboratory markers for patients who would benefit from more intensive treatment. ..
- American Society for Rickettsiology conferenceROMAN GANTA; Fiscal Year: 2005..abstract_text> ..
- Ehrlichia chaffeensis protective proteinsDavid H Walker; Fiscal Year: 2010..chaffeensis. ..
- Gammacell-220 Excel Refurbished Research IrradiatorDavid Walker; Fiscal Year: 2006..unreadable] [unreadable]..
- Identification of Anaplasma phagocytophilum adhesinsJASON CARLYON; Fiscal Year: 2006DESCRIPTION (provided by applicant): Human granulocytic anaplasmosis (HGA; formerly human granulocytic ehrlichiosis) is an emerging and potentially deadly disease...
- LYME ARTHRITIS: A NEW EPIDEMIC DISEASEAllen C Steere; Fiscal Year: 2010..Furthermore, this work brings us closer to the long-term goal of direct comparisons of antigens in Lyme arthritis and rheumatoid arthritis synovia. ..
- Regulation of gp91phox by Anaplasma phagocytophilaVenetta Thomas; Fiscal Year: 2007..Aim 2. To define the effect of A. phagocytophila infection on the activity of the activator proteins and their binding capacity of the gp91phox promoter. ..
- Natural History of Borrelia lonestariSusan Little; Fiscal Year: 2006..S., enhancing public health efforts in those areas where people are risk of infection; reduction in human disease from these pathogens should result. [unreadable] [unreadable] [unreadable] [unreadable]..
- American Society for Rickettsiology Conference 2006ROMAN GANTA; Fiscal Year: 2006..abstract_text> ..