upper gastrointestinal tract

Summary

Summary: The segment of GASTROINTESTINAL TRACT that includes the ESOPHAGUS; the STOMACH; and the DUODENUM.

Top Publications

  1. van Leerdam M. Epidemiology of acute upper gastrointestinal bleeding. Best Pract Res Clin Gastroenterol. 2008;22:209-24 pubmed publisher
    ..H. pylori infection is found in about 50% of peptic ulcer bleeding patients. H. pylori should be tested for in all ulcer patients and eradication should be given...
  2. Zhang S, Cui Y, Gong X, Gu F, Chen M, Zhong B. Endoscopic management of foreign bodies in the upper gastrointestinal tract in South China: a retrospective study of 561 cases. Dig Dis Sci. 2010;55:1305-12 pubmed publisher
    ..The aim of this study is to investigate the clinical features of FB ingestion in South China and report its management through endoscopy...
  3. Karczewska E, Wojtas I, Sito E, Trojanowska D, Budak A, Zwolinska Wcislo M, et al. Assessment of co-existence of Helicobacter pylori and Candida fungi in diseases of the upper gastrointestinal tract. J Physiol Pharmacol. 2009;60 Suppl 6:33-9 pubmed
    ..pylori. Analysis of relationship between selected disorders of the upper gastrointestinal tract (non ulcer dyspepsia NUD, gastric ulcer, duodenal ulcer) and infection with H...
  4. Robustelli U, Bellotti R, Scardi F, Fortunato Armellino M, De Masi A, Forner A, et al. Management of corrosive injuries of the upper gastrointestinal tract. Our experience in 58 patients. G Chir. 2011;32:188-93 pubmed
    ..The ingestion of caustic substances is one of the most difficult conditions to be treated in Emergency Department...
  5. Mortensen M, Fristrup C, Ainsworth A, Pless T, Nielsen H, Hovendal C. Combined preoperative endoscopic and laparoscopic ultrasonography for prediction of R0 resection in upper gastrointestinal tract cancer. Br J Surg. 2006;93:720-5 pubmed
    This study evaluated the ability of combined endoscopic and laparoscopic ultrasonography to predict R0 resection and avoid unnecessary surgery in patients with upper gastrointestinal tract cancer (UGIC).
  6. Contini S, Scarpignato C. Caustic injury of the upper gastrointestinal tract: a comprehensive review. World J Gastroenterol. 2013;19:3918-30 pubmed publisher
    ..Possible late development of esophageal cancer, though probably overemphasized, entails careful and long-term endoscopic screening. ..
  7. Young R, Sutherland K, Pezos N, Brierley S, Horowitz M, Rayner C, et al. Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes. Gut. 2009;58:337-46 pubmed publisher
    ..These taste molecules are also present in the rodent small intestine, and may regulate gastrointestinal function...
  8. Prasad P, Wittmann J, Pereira S. Endoscopic ultrasound of the upper gastrointestinal tract and mediastinum: diagnosis and therapy. Cardiovasc Intervent Radiol. 2006;29:947-57 pubmed
    ..Emerging investigational techniques include EUS-guided enteric anastomosis formation and fine-needle injection therapy for malignant disease...
  9. Katsanos K, Sabharwal T, Adam A. Stenting of the upper gastrointestinal tract: current status. Cardiovasc Intervent Radiol. 2010;33:690-705 pubmed publisher
    Minimally invasive image-guided insertion of self-expanding metal stents in the upper gastrointestinal tract is the current treatment of choice for palliation of malignant esophageal or gastroduodenal outlet obstructions...

Scientific Experts

More Information

Publications62

  1. Izol B, Karabulut A, Biyikoglu I, Gonultas M, Eksioglu M. Investigation of upper gastrointestinal tract involvement and H. pylori presence in lichen planus: a case-controlled study with endoscopic and histopathological findings. Int J Dermatol. 2010;49:1121-6 pubmed publisher
    ..Infectious agents including H. pylori and other autoantigens have been investigated in etiology and association with certain gastrointestinal pathologies have been well documented...
  2. Manner H, May A, Faerber M, Rabenstein T, Ell C. Safety and efficacy of a new high power argon plasma coagulation system (hp-APC) in lesions of the upper gastrointestinal tract. Dig Liver Dis. 2006;38:471-8 pubmed
    The aim of this study was to analyze safety and efficacy of a new high power argon plasma coagulation system in the upper gastrointestinal tract.
  3. Cryer B, Binkley N, Simonelli C, Lewiecki E, Lanza F, Chen E, et al. A randomized, placebo-controlled, 6-month study of once-weekly alendronate oral solution for postmenopausal osteoporosis. Am J Geriatr Pharmacother. 2005;3:127-36 pubmed
    ..This study evaluated the overall safety and tolerability of once-weekly (OW) alendronate 70 mg oral solution (OS) versus OW placebo OS...
  4. Lu B, Chen L, Liu L, Zhu Y, Wu C, Jiang J, et al. T-cell-mediated tumor immune surveillance and expression of B7 co-inhibitory molecules in cancers of the upper gastrointestinal tract. Immunol Res. 2011;50:269-75 pubmed publisher
    ..Future tumor vaccine design should combine blockade of B7 inhibitory molecules and enhancement of T-bet and Eomes levels within the tumor microenvironment...
  5. Vlavianos P, Zabron A. Clinical outcomes, quality of life, advantages and disadvantages of metal stent placement in the upper gastrointestinal tract. Curr Opin Support Palliat Care. 2012;6:27-32 pubmed publisher
    ..Over recent years, indications such as benign disease have expanded, as has SEMS diversity with self-expandable plastic stents (SEPSs) or fully covered and biodegradable stents, for example...
  6. Sharaf R, Weinshel E, Bini E, Rosenberg J, Ren C. Radiologic assessment of the upper gastrointestinal tract: does it play an important preoperative role in bariatric surgery?. Obes Surg. 2004;14:313-7 pubmed
    ..The role of upper GI series (UGIS) before bariatric surgery is controversial. The aim of this study was to evaluate the diagnostic yield and cost of routine UGIS prior to bariatric surgery...
  7. Trawick E, Yachimski P. Management of non-variceal upper gastrointestinal tract hemorrhage: controversies and areas of uncertainty. World J Gastroenterol. 2012;18:1159-65 pubmed publisher
    b>Upper gastrointestinal tract hemorrhage (UGIH) remains a common presentation requiring urgent evaluation and treatment...
  8. Bannert C, Bidmon Fliegenschnee B, Stary G, Hotzy F, Stift J, Nurko S, et al. Fc-epsilon-RI, the high affinity IgE-receptor, is robustly expressed in the upper gastrointestinal tract and modulated by mucosal inflammation. PLoS ONE. 2012;7:e42066 pubmed publisher
    ..Currently, a detailed characterization of Fc?RI expression throughout the human gut is lacking. The aim of this study was to define the expression pattern of Fc?RI in the GI tract...
  9. Chen Z, Scudiere J, Montgomery E. Medication-induced upper gastrointestinal tract injury. J Clin Pathol. 2009;62:113-9 pubmed publisher
  10. Kaye P, Abdulla K, Wood J, James P, Foley S, Ragunath K, et al. Iron-induced mucosal pathology of the upper gastrointestinal tract: a common finding in patients on oral iron therapy. Histopathology. 2008;53:311-7 pubmed publisher
    ..Upper gastrointestinal injury from iron tablets at therapeutic dose is not widely recognized. The aim was to document cases of iron-related upper gastrointestinal (GI) pathology and to determine frequency of occurrence...
  11. Gencosmanoglu R, Sen Oran E, Kurtkaya Yapicier O, Tozun N. Xanthelasmas of the upper gastrointestinal tract. J Gastroenterol. 2004;39:215-9 pubmed
    ..Gastric xanthelasma is a benign and uncommon lesion with a variably reported frequency, while esophageal and duodenal xanthelasmas are quite rare...
  12. Macfarlane S, Furrie E, Macfarlane G, Dillon J. Microbial colonization of the upper gastrointestinal tract in patients with Barrett's esophagus. Clin Infect Dis. 2007;45:29-38 pubmed
    ..The aim of this study was to characterize microbial communities in esophageal aspirate specimens and on distal esophageal mucosal samples from patients with BE...
  13. Song H, Shin J, Lim J, Kim T, Lee G, Lee S. Use of a newly designed multifunctional coil catheter for stent placement in the upper gastrointestinal tract. J Vasc Interv Radiol. 2004;15:369-73 pubmed
    To evaluate the usefulness of a newly designed multifunctional coil catheter for stent placement in patients with upper gastrointestinal tract strictures.
  14. Chaves D, Ishioka S, Felix V, Sakai P, Gama Rodrigues J. Removal of a foreign body from the upper gastrointestinal tract with a flexible endoscope: a prospective study. Endoscopy. 2004;36:887-92 pubmed
    ..far been no prospective studies on the value of flexible endoscopy for removing foreign bodies in the upper gastrointestinal tract. This study presents a clinical analysis of accidents with foreign bodies and prospectively evaluates ..
  15. Keh S, Onyekwelu N, McManus K, McGuigan J. Corrosive injury to upper gastrointestinal tract: Still a major surgical dilemma. World J Gastroenterol. 2006;12:5223-8 pubmed
    ..In this article, we present our experience of two contrasting cases of corrosive injury to the upper gastrointestinal tract in our thoracic unit in the last 2 years and an up-to-date Medline literature search has been carried ..
  16. Dambacher J, Staudinger T, Seiderer J, Sisic Z, Schnitzler F, Pfennig S, et al. Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease. Inflamm Bowel Dis. 2007;13:71-82 pubmed
    ..The aim of the study was to analyze the role of the MIF -173G/C single nucleotide polymorphism in Crohn's disease (CD)...
  17. Lee C, Liu K, Wang H, Chen S, Tsang Y, Liu H. Transcatheter arterial embolization of acute upper gastrointestinal tract bleeding with N-butyl-2-cyanoacrylate. J Vasc Interv Radiol. 2007;18:209-16 pubmed
    PURPOSEl: To retrospectively analyze outcomes in patients who received an iodized oil formulation of N-butyl-2-cyanoacrylate to treat acute nonvariceal upper gastrointestinal tract bleeding.
  18. Leung Ki E, Chan F. Interaction of Helicobacter pylori infection and low-dose aspirin in the upper gastrointestinal tract: implications for clinical practice. Best Pract Res Clin Gastroenterol. 2012;26:163-72 pubmed publisher
    Low-dose aspirin has been shown to increase the risk of upper gastrointestinal tract injury...
  19. Valkhoff V, van Soest E, Mazzaglia G, Molokhia M, Schade R, Trifiro G, et al. Adherence to gastroprotection during cyclooxygenase 2 inhibitor treatment and the risk of upper gastrointestinal tract events: a population-based study. Arthritis Rheum. 2012;64:2792-802 pubmed publisher
    ..We undertook this study to determine the association between GPA adherence and UGI tract events among patients receiving coxibs...
  20. Pitino I, Randazzo C, Mandalari G, Lo Curto A, Faulks R, Le Marc Y, et al. Survival of Lactobacillus rhamnosus strains in the upper gastrointestinal tract. Food Microbiol. 2010;27:1121-7 pubmed publisher
    ..probiotic Lactobacillus rhamnosus strains were investigated for their ability to survive in the human upper gastrointestinal tract through a dynamic gastric model of digestion...
  21. Olokoba A, Olokoba L, Jimoh A, Salawu F, Danburam A, Ehalaiye B. Upper gastrointestinal tract endoscopy indications in northern Nigeria. J Coll Physicians Surg Pak. 2009;19:327-8 pubmed publisher
    b>Upper gastrointestinal tract endoscopy is one of the commonly performed endoscopic procedures, and has only recently become available in Nigeria...
  22. Das A, Wilson R, Biankin A, Merrett N. Surgical therapy for gastrointestinal stromal tumours of the upper gastrointestinal tract. J Gastrointest Surg. 2009;13:1220-5 pubmed publisher
    This study aimed to examine clinicopathological features and outcomes after primary resection of gastrointestinal stromal tumours (GIST) of the upper gastrointestinal tract
  23. Katsinelos P, Kountouras J, Paroutoglou G, Zavos C, Mimidis K, Chatzimavroudis G. Endoscopic techniques and management of foreign body ingestion and food bolus impaction in the upper gastrointestinal tract: a retrospective analysis of 139 cases. J Clin Gastroenterol. 2006;40:784-9 pubmed
    ..Successful foreign body and food bolus removal may depend on the method used, the choice of device, and the experience level of the endoscopist, although few papers report experience and outcome of tertiary centers...
  24. Pihl L, Wilander E, Nylander O. Comparative study of the effect of luminal hypotonicity on mucosal permeability in rat upper gastrointestinal tract. Acta Physiol (Oxf). 2008;193:67-78 pubmed
    ..To investigate whether the increase in mucosal permeability in the duodenum, induced by luminal hypotonicity, also occurs in the stomach and the jejunum and whether this increase in permeability can be explained by epithelial injury...
  25. Chen I, Hung M, Chiu T, Chen J, Hsiao C. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding. Am J Emerg Med. 2007;25:774-9 pubmed
    ..Our study aims to compare Blatchford score with clinical Rockall score and complete Rockall score in their utilities in identifying high-risk cases in patients with acute nonvariceal UGIB...
  26. Enestvedt B, Gralnek I, Mattek N, Lieberman D, Eisen G. An evaluation of endoscopic indications and findings related to nonvariceal upper-GI hemorrhage in a large multicenter consortium. Gastrointest Endosc. 2008;67:422-9 pubmed publisher
    ..There is limited information about patients with UGIH who are evaluated by endoscopy at nonacademic settings, which comprise the majority of endoscopic practices in the United States...
  27. Haig A, Driman D. Iron-induced mucosal injury to the upper gastrointestinal tract. Histopathology. 2006;48:808-12 pubmed
    ..To define the causes and associations of mucosal iron deposition in upper gastrointestinal biopsy specimens and to describe the morphological features of iron-related injury...
  28. Wolfsen H, Hemminger L, Achem S, Loeb D, Stark M, Bouras E, et al. Complications of endoscopy of the upper gastrointestinal tract: a single-center experience. Mayo Clin Proc. 2004;79:1264-7 pubmed
    To evaluate prospectively the complications that occurred during consecutive endoscopies of the upper gastrointestinal tract.
  29. Hosaka Y, Koslowski M, Nuding S, Wang G, Schlee M, Schäfer C, et al. Antimicrobial host defense in the upper gastrointestinal tract. Eur J Gastroenterol Hepatol. 2008;20:1151-8 pubmed publisher
    ..Herein, we aimed to systematically assess the distribution and quantity of different antimicrobial host factors as well as, for the first time, functional mucosal antimicrobial activity in the upper gastrointestinal tract.
  30. Rosivatz E, Becker K, Kremmer E, Schott C, Blechschmidt K, Hofler H, et al. Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract. Virchows Arch. 2006;448:277-87 pubmed
    ..Subsequently, a series of 340 adenocarcinomas of the upper gastrointestinal tract, including tumours from the oesophagus (n=154), cardia (n=102) and stomach (n=84), arranged in tissue ..
  31. Tohda G, Sugawa C, Gayer C, Chino A, McGuire T, Lucas C. Clinical evaluation and management of caustic injury in the upper gastrointestinal tract in 95 adult patients in an urban medical center. Surg Endosc. 2008;22:1119-25 pubmed
    ..This retrospective study of adult patients with caustic injury presents the endoscopic findings, treatment regimen, and clinical outcome...
  32. Park J, Park C, Park J, Lee S, Lee W, Joo Y, et al. [Review of 209 cases of foreign bodies in the upper gastrointestinal tract and clinical factors for successful endoscopic removal]. Korean J Gastroenterol. 2004;43:226-33 pubmed
    ..The aims of this study were to characterize the clinical features associated with foreign bodies in the upper gastrointestinal tract and to determine the clinical factors for their successful removal by endoscopic techniques.
  33. Song S, Ajani J. The role of microRNAs in cancers of the upper gastrointestinal tract. Nat Rev Gastroenterol Hepatol. 2013;10:109-18 pubmed publisher
    Cancers of the oesophagus, gastro-oesophageal junction and stomach (upper gastrointestinal tract cancers; UGICs) pose a major health risk around the world...
  34. Kheadr E, Zihler A, Dabour N, Lacroix C, Le Blay G, Fliss I. Study of the physicochemical and biological stability of pediocin PA-1 in the upper gastrointestinal tract conditions using a dynamic in vitro model. J Appl Microbiol. 2010;109:54-64 pubmed publisher
    ..To investigate the physicochemical and biological stability of purified pediocin PA-1 under GIT conditions...
  35. Konturek S, Konturek P, Brzozowski T, Bubenik G. Role of melatonin in upper gastrointestinal tract. J Physiol Pharmacol. 2007;58 Suppl 6:23-52 pubmed
    ..This review concentrates on the generation and pathophysiological implication of melatonin in upper GIT...
  36. Garcia Rodriguez L, Barreales Tolosa L. Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population. Gastroenterology. 2007;132:498-506 pubmed
    ..Whether use of selective inhibitors of cyclooxygenase-2 (COXIBs) will translate into a clinically relevant reduced toxicity has not been widely investigated in the general population...
  37. Stanley A, Dalton H, Blatchford O, Ashley D, Mowat C, Cahill A, et al. Multicentre comparison of the Glasgow Blatchford and Rockall Scores in the prediction of clinical end-points after upper gastrointestinal haemorrhage. Aliment Pharmacol Ther. 2011;34:470-5 pubmed publisher
    ..The Glasgow Blatchford Score (GBS) is increasingly being used to predict intervention and outcome following upper gastrointestinal haemorrhage (UGIH)...
  38. Jadcherla S. Pathophysiology of aerodigestive pulmonary disorders in the neonate. Clin Perinatol. 2012;39:639-54 pubmed
    ..Objective evaluation of aerodigestive reflexes and symptom correlation may provide support for evidence-based personalized management of feeding and airway protection strategies...
  39. Crooks C, West J, Card T. Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding. Gastroenterology. 2013;144:1384-93, 1393.e1-2; quiz e18-9 pubmed publisher
    ..Other factors might therefore be involved in the pathogenesis of GIB. Patients with GIB have increasing nongastrointestinal comorbidity, so we investigated whether comorbidity itself increased the risk of GIB...
  40. Meyer H. [Clinical aspects of premalignant lesions of the upper gastrointestinal tract]. Pathologe. 2011;32 Suppl 2:202-5 pubmed publisher
    ..genetic and epigenetic aberrations are discussed in the multistep carcinogenesis of tumors of the upper gastrointestinal tract but specific genetic changes are still unknown...
  41. Verma B, Murari A, Aggarwal K, Rani Y. A post-mortem study of the upper gastro-intestinal tract in head injury cases. Med Sci Law. 2007;47:51-5 pubmed
    ..The severity of the damage increased with survival time. The damage observed was in the form of congestion, mucosal haemorrhage, superficial erosions, and superficial ulcerations accompanied by frank haemorrhage...
  42. Ferreira D, Pinto V, Correia J, Minas G. Spectroscopic detection of gastrointestinal dysplasia using optical microsensors. IEEE Trans Biomed Eng. 2011;58:2633-9 pubmed publisher
    ..8% and 97.6%, respectively. Therefore, the developed filters can be used as a tool to aid in diagnosis. The small size of the optical microsensors can enable, in the future, integration in endoscopic capsules...
  43. Zerbib P, Voisin B, Truant S, Saulnier F, Vinet A, Chambon J, et al. The conservative management of severe caustic gastric injuries. Ann Surg. 2011;253:684-8 pubmed publisher
    ..To determine the safety of a conservative approach to treating severe caustic injury in patients lacking clinical and biochemical signs of transmural necrosis...
  44. Greenspoon J, Barkun A. The pharmacological therapy of non-variceal upper gastrointestinal bleeding. Gastroenterol Clin North Am. 2010;39:419-32 pubmed publisher
    ..The most important clinically relevant data are presented, favoring fully published articles...
  45. Masuda E, Kommers G, Martins T, Barros C, Piazer J. Morphological factors as indicators of malignancy of squamous cell carcinomas in cattle exposed naturally to bracken fern (Pteridium aquilinum). J Comp Pathol. 2011;144:48-54 pubmed publisher
    ..The morphological factors analyzed were all related to histological grading, which is the major factor predicting the biological behaviour of SCCs in cattle naturally exposed to bracken fern...
  46. Scheiman J. Unmet needs in non-steroidal anti-inflammatory drug-induced upper gastrointestinal diseases. Drugs. 2006;66 Suppl 1:15-21; discussion 29-33 pubmed
    ..This article examines the current issues of understanding and managing NSAID-induced upper gastrointestinal diseases...
  47. Szopinski J, Lochner G, Pantanowitz D. Influence of organ pathology on the electrical parameters in organ projection areas of the skin. J Tradit Chin Med. 2006;26:218-25 pubmed
    ..The degree of rectification or difference in impedance is proportional to the extent of the pathological process within the related organ...
  48. Pilotto A, Maggi S, Noale M, Franceschi M, Parisi G, Crepaldi G. Association of upper gastrointestinal symptoms with functional and clinical charateristics in elderly. World J Gastroenterol. 2011;17:3020-6 pubmed publisher
    ..To evaluate the prevalence of upper gastrointestinal symptoms and their association with clinical and functional characteristics in elderly outpatients...
  49. Balan K, Sonoda L, Seshadri N, Solanki C, Middleton S. Clinical significance of scintigraphic rapid gastric emptying. Nucl Med Commun. 2011;32:1185-9 pubmed publisher
    ..To analyse our results of gastric-emptying scintigraphy in relation to presenting symptoms, and examine in detail the clinical significance of rapid gastric emptying (RGE)...
  50. Zhang W, Qian X, Shi Y, Pan W, Xu X, Ye Z, et al. Multiple primary malignant neoplasms of three early cancer lesions: a case report. Chin Med J (Engl). 2011;124:1278-80 pubmed
    ..Here reported a case of 62-year-old man with concomitant three early stage cancer lesions in upper gastrointestinal tract, all of which were detected by endoscopy...
  51. Cho J. [What is the principle of endoscopic removal technique of foreign bodies in the upper gastrointestinal tract?]. Korean J Gastroenterol. 2004;43:324-7 pubmed
  52. Abraham N, Cohen D, Rivers B, Richardson P. Validation of administrative data used for the diagnosis of upper gastrointestinal events following nonsteroidal anti-inflammatory drug prescription. Aliment Pharmacol Ther. 2006;24:299-306 pubmed
    ..To validate veterans affairs (VA) administrative data for the diagnosis of nonsteroidal anti-inflammatory drug (NSAID)-related upper gastrointestinal events (UGIE) and to develop a diagnostic algorithm...
  53. Embu H, Misauno M, Isamade E, Yilkudi M. Unsedated flexible upper gastrointestinal endoscopy: need for routine oxygen monitoring?. Niger J Med. 2008;17:443-6 pubmed
    ..To determine the incidence of oxygen desaturation and whether routine oxygen monitoring is necessary during unsedated diagnostic flexible upper gastrointestinalendoscopy...