intestinal atresia

Summary

Summary: Congenital obliteration of the lumen of the intestine, with the ILEUM involved in 50% of the cases and the JEJUNUM and DUODENUM following in frequency. It is the most frequent cause of INTESTINAL OBSTRUCTION in NEWBORNS. (From Stedman, 25th ed)

Top Publications

  1. Fairbanks T, Sala F, Kanard R, Curtis J, Del Moral P, De Langhe S, et al. The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia. J Pediatr Surg. 2006;41:132-6; discussion 132-6 pubmed
    b>Intestinal atresia occurs in 1:5000 live births and is a neonatal challenge...
  2. Sadler T, Rasmussen S. Examining the evidence for vascular pathogenesis of selected birth defects. Am J Med Genet A. 2010;152A:2426-36 pubmed publisher
    ..These conclusions are important for counseling parents of children with these defects and for guiding the design of future epidemiological studies and experiments to further characterize the causes of these defects. ..
  3. Burjonrappa S, Crete E, Bouchard S. Prognostic factors in jejuno-ileal atresia. Pediatr Surg Int. 2009;25:795-8 pubmed publisher
    ..Primarily to study morbidity and mortality in jejuno-ileal atresias (JIA) and prognostic factors for outcome. Secondarily to look at the incidence of reintervention...
  4. Pratap A, Yadav R, Bajracharya A, Agrawal A, Bhatta N, Agrawal C. Intrauterine omphalic ileal entrapment as an unusual cause of ileal atresia: report of a case. Surg Today. 2008;38:141-3 pubmed publisher
    ..Laparotomy revealed that the distal part of the ileum was entrapped within the omphalic ring and that this entrapped segment of ileum was atretic. To our knowledge, this potential mechanism of IA has not been described before...
  5. van Bever Y, van Hest L, Wolfs R, Tibboel D, van den Hoonaard T, Gischler S. Exclusion of a PAX6, FOXC1, PITX2, and MYCN mutation in another patient with apple peel intestinal atresia, ocular anomalies and microcephaly and review of the literature. Am J Med Genet A. 2008;146A:500-4 pubmed publisher
    We describe another patient with the combination of apple peel intestinal atresia, microcephaly, microphthalmia, and anterior eye chamber anomalies...
  6. Walker K, Badawi N, Hamid C, Vora A, Halliday R, Taylor C, et al. A population-based study of the outcome after small bowel atresia/stenosis in New South Wales and the Australian Capital Territory, Australia, 1992-2003. J Pediatr Surg. 2008;43:484-8 pubmed publisher
    ..Although the mortality rate has decreased over the last 50 years, it remains substantial at 8% and is higher in premature and low birth weight infants. ..
  7. Kronfli R, Bradnock T, Sabharwal A. Intestinal atresia in association with gastroschisis: a 26-year review. Pediatr Surg Int. 2010;26:891-4 pubmed publisher
    We reviewed our experience with gastroschisis (GS) complicated by intestinal atresia over the last 26 years...
  8. Chirdan L, Uba A, Pam S. Intestinal atresia: management problems in a developing country. Pediatr Surg Int. 2004;20:834-7 pubmed
    Over a 13-year period, 24 children with intestinal atresia were managed at the Jos University Teaching Hospital, Jos, Nigeria...
  9. Khen Dunlop N, Fourcade L, Sauvat F, de Lambert G, Victor A, Cerf Bensussan N, et al. Surgical experimental jejunoileal atresia in rat embryo. J Pediatr Surg. 2009;44:1725-9 pubmed publisher
    Jejunoileal atresia represents about 40% of intestinal atresia. After surgical repair, intestinal motility disorders are burdened with the postoperative outcome, and the origin of these troubles remains unclear...
  10. Werler M, Sheehan J, Mitchell A. Association of vasoconstrictive exposures with risks of gastroschisis and small intestinal atresia. Epidemiology. 2003;14:349-54 pubmed
    Gastroschisis and small intestinal atresia are congenital anomalies that may arise from vascular disruption...

Detail Information

Publications62

  1. Fairbanks T, Sala F, Kanard R, Curtis J, Del Moral P, De Langhe S, et al. The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia. J Pediatr Surg. 2006;41:132-6; discussion 132-6 pubmed
    b>Intestinal atresia occurs in 1:5000 live births and is a neonatal challenge...
  2. Sadler T, Rasmussen S. Examining the evidence for vascular pathogenesis of selected birth defects. Am J Med Genet A. 2010;152A:2426-36 pubmed publisher
    ..These conclusions are important for counseling parents of children with these defects and for guiding the design of future epidemiological studies and experiments to further characterize the causes of these defects. ..
  3. Burjonrappa S, Crete E, Bouchard S. Prognostic factors in jejuno-ileal atresia. Pediatr Surg Int. 2009;25:795-8 pubmed publisher
    ..Primarily to study morbidity and mortality in jejuno-ileal atresias (JIA) and prognostic factors for outcome. Secondarily to look at the incidence of reintervention...
  4. Pratap A, Yadav R, Bajracharya A, Agrawal A, Bhatta N, Agrawal C. Intrauterine omphalic ileal entrapment as an unusual cause of ileal atresia: report of a case. Surg Today. 2008;38:141-3 pubmed publisher
    ..Laparotomy revealed that the distal part of the ileum was entrapped within the omphalic ring and that this entrapped segment of ileum was atretic. To our knowledge, this potential mechanism of IA has not been described before...
  5. van Bever Y, van Hest L, Wolfs R, Tibboel D, van den Hoonaard T, Gischler S. Exclusion of a PAX6, FOXC1, PITX2, and MYCN mutation in another patient with apple peel intestinal atresia, ocular anomalies and microcephaly and review of the literature. Am J Med Genet A. 2008;146A:500-4 pubmed publisher
    We describe another patient with the combination of apple peel intestinal atresia, microcephaly, microphthalmia, and anterior eye chamber anomalies...
  6. Walker K, Badawi N, Hamid C, Vora A, Halliday R, Taylor C, et al. A population-based study of the outcome after small bowel atresia/stenosis in New South Wales and the Australian Capital Territory, Australia, 1992-2003. J Pediatr Surg. 2008;43:484-8 pubmed publisher
    ..Although the mortality rate has decreased over the last 50 years, it remains substantial at 8% and is higher in premature and low birth weight infants. ..
  7. Kronfli R, Bradnock T, Sabharwal A. Intestinal atresia in association with gastroschisis: a 26-year review. Pediatr Surg Int. 2010;26:891-4 pubmed publisher
    We reviewed our experience with gastroschisis (GS) complicated by intestinal atresia over the last 26 years...
  8. Chirdan L, Uba A, Pam S. Intestinal atresia: management problems in a developing country. Pediatr Surg Int. 2004;20:834-7 pubmed
    Over a 13-year period, 24 children with intestinal atresia were managed at the Jos University Teaching Hospital, Jos, Nigeria...
  9. Khen Dunlop N, Fourcade L, Sauvat F, de Lambert G, Victor A, Cerf Bensussan N, et al. Surgical experimental jejunoileal atresia in rat embryo. J Pediatr Surg. 2009;44:1725-9 pubmed publisher
    Jejunoileal atresia represents about 40% of intestinal atresia. After surgical repair, intestinal motility disorders are burdened with the postoperative outcome, and the origin of these troubles remains unclear...
  10. Werler M, Sheehan J, Mitchell A. Association of vasoconstrictive exposures with risks of gastroschisis and small intestinal atresia. Epidemiology. 2003;14:349-54 pubmed
    Gastroschisis and small intestinal atresia are congenital anomalies that may arise from vascular disruption...
  11. Werler M, Sheehan J, Mitchell A. Maternal medication use and risks of gastroschisis and small intestinal atresia. Am J Epidemiol. 2002;155:26-31 pubmed
    Gastroschisis and small intestinal atresia (SIA) are birth defects that are thought to arise from vascular disruption of fetal mesenteric vessels...
  12. Georgeson K, Robertson D. Minimally invasive surgery in the neonate: review of current evidence. Semin Perinatol. 2004;28:212-20 pubmed
    ..This article summarizes the status of these techniques in neonates. ..
  13. Baerg J, Kaban G, Tonita J, Pahwa P, Reid D. Gastroschisis: A sixteen-year review. J Pediatr Surg. 2003;38:771-4 pubmed
    ..85 in 1985 to 1990 to 3.66 in 1991 to 1995 to 4.06 in 1996 to 2000. The analysis found that intestinal atresia P =.009, OR = 18.3 (95%CI: 2.457-136) and intestinal necrosis P =.050, OR = 10.33 (95%CI: 1.32-80...
  14. Spineli Silva S, Bispo L, Gil da Silva Lopes V, Vieira T. Distal deletion at 22q11.2 as differential diagnosis in Craniofacial Microsomia: Case report and literature review. Eur J Med Genet. 2018;61:262-268 pubmed publisher
    ..malar hypoplasia, cleft lip and palate, mild asymmetry of soft tissue in face, congenital heart disease, intestinal atresia, annular pancreas and hydronephrosis...
  15. Nakayama D. Sir Denis Browne, the father of modern pediatric surgery. J Pediatr Surg. 2018;53:576-579 pubmed publisher
    ..incision, primary repair of congenital intestinal obstruction, and the end-to-back anastomosis for intestinal atresia, techniques so commonly used that it is difficult to think of pediatric surgical operations done any ..
  16. Escobar M, Ladd A, Grosfeld J, West K, Rescorla F, Scherer L, et al. Duodenal atresia and stenosis: long-term follow-up over 30 years. J Pediatr Surg. 2004;39:867-71; discussion 867-71 pubmed
    ..Follow-up of these patients into adulthood is recommended to identify and address these late occurrences. ..
  17. Al Salem A. Congenital pyloric atresia and associated anomalies. Pediatr Surg Int. 2007;23:559-63 pubmed
    ..CPA in association with EB has a high mortality but there are encouraging results with the use of steroids and phenytoin. Sepsis continues to be the main cause of death and an associated combined immunodeficiency should be excluded. ..
  18. Cairo S, Kakembo N, Kisa P, Muzira A, CHEUNG M, Healy J, et al. Disparity in access and outcomes for emergency neonatal surgery: intestinal atresia in Kampala, Uganda. Pediatr Surg Int. 2017;33:907-915 pubmed publisher
    b>Intestinal atresia is one of the leading causes of neonatal intestinal obstruction (NIO)...
  19. Bagci S, Brosens E, Tibboel D, de Klein A, Ijsselstijn H, Wijers C, et al. More than fetal urine: enteral uptake of amniotic fluid as a major predictor for fetal growth during late gestation. Eur J Pediatr. 2016;175:825-31 pubmed publisher
    ..adapted for birth weights (BW z-scores) for each of 517 European newborns with congenital pre-gastric intestinal atresia, i.e., EA, to a European reference population...