Genomes and Genes
oxygen inhalation therapy
Summary: Inhalation of oxygen aimed at restoring toward normal any pathophysiologic alterations of gas exchange in the cardiopulmonary system, as by the use of a respirator, nasal catheter, tent, chamber, or mask. (From Dorland, 27th ed & Stedman, 25th ed)
Publications191 found, 100 shown here
- Benefits of oxygen on exercise performance and pulmonary hemodynamics in patients with COPD with mild hypoxemiaKeisaku Fujimoto
First Department of Internal Medicine, Shinshu University School of Medicine, Asahi, Matsumoto, Japan
Chest 122:457-63. 2002..To clarify the effects of oxygen on exercise performance and pulmonary hemodynamics during exercise in patients with COPD with mild hypoxemia at rest...
- Giving small babies oxygen: 50 years of uncertaintyWin Tin
Department of Paediatrics, The James Cook University Hospital, Middlesbrough TS4 3BW, UK
Semin Neonatol 7:361-7. 2002..This is particularly important in babies of less than 28 weeks' gestation, who remain, currently, at serious risk of chronic lung disease and permanent retinal scarring...
- Acute exacerbations of chronic obstructive pulmonary diseaseKenneth H Palm
Department of Emergency Medicine, Mayo Medical School, Mayo Clinic 200 First Street SW, Rochester, MN 55905, USA
Emerg Med Clin North Am 21:331-52, viii. 2003..The focus is on the presentation of acute exacerbations of COPD in the emergency department and the available evidence for testing and treatment...
- Managing acute respiratory failure during exacerbation of chronic obstructive pulmonary diseaseGreg L Schumaker
Pulmonary, Critical Care, and Sleep Division, Tufts-New England Medical Center, Boston, Massachusetts, USA
Respir Care 49:766-82. 2004..For invasively ventilated patients the clinical emphasis should be on improving patient-ventilator interaction and avoiding dynamic hyperinflation (intrinsic positive end-expiratory pressure)...
- Achieved versus intended pulse oximeter saturation in infants born less than 28 weeks' gestation: the AVIOx studyJames I Hagadorn
Division of Neonatology, Connecticut Children s Medical Center, 282 Washington St, Hartford, CT 06106, USA
Pediatrics 118:1574-82. 2006....
- Randomised trial of ambulatory oxygen in oxygen-dependent COPDY Lacasse
Centre de Pneumologie, Hopital Laval, 2725 Chemin Ste Foy, Ste Foy, Quebec, G1V 4G5, Canada
Eur Respir J 25:1032-8. 2005..Ambulatory oxygen had no effect on any of the outcomes. In conclusion, the current results do not support the widespread provision of ambulatory oxygen to patients with oxygen-dependent chronic obstructive pulmonary disease...
- Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestationW Tin
Department of Paediatrics, South Cleveland Hospital, Middlesbrough TS4 3BW, UK
Arch Dis Child Fetal Neonatal Ed 84:F106-10. 2001....
- Impact of a physiologic definition on bronchopulmonary dysplasia ratesMichele C Walsh
Rainbow Babies and Childrens Hospital, Department of Pediatrics, CASE Case Western Reserve University, 11100 Euclid Ave, Mailstop 6010, Cleveland, OH 44106, USA
Pediatrics 114:1305-11. 2004..Safety (apnea, bradycardia, increased oxygen use) and outcomes of the physiologic definition versus the clinical definition were assessed...
- Meeting oxygen needs in Africa: an options analysis from the GambiaStephen R C Howie
Bacterial Diseases Programme, Medical Research Council Laboratories, Banjul, Gambia
Bull World Health Organ 87:763-71. 2009..To compare oxygen supply options for health facilities in the Gambia and develop a decision-making algorithm for choosing oxygen delivery systems in Africa and the rest of the developing world...
- Oxygen-saturation targets and outcomes in extremely preterm infantsLisa Maree Askie
Centre for Perinatal Health Services Research, University of Sydney, NSW, Australia
N Engl J Med 349:959-67. 2003..Anecdotal reports and uncontrolled observational studies have suggested that a higher oxygen-saturation range may be beneficial in terms of growth and development...
- Oxygen for treatment of severe pneumonia in The Gambia, West Africa: a situational analysisS E Hill
Department of Public Health, University of Otago, Wellington, New Zealand
Int J Tuberc Lung Dis 13:587-93. 2009..Health facilities in The Gambia, West Africa...
- A pilot study of normobaric oxygen therapy in acute ischemic strokeAneesh B Singhal
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
Stroke 36:797-802. 2005..Therapies that transiently prevent ischemic neuronal death can potentially extend therapeutic time windows for stroke thrombolysis. We conducted a pilot study to investigate the effects of high-flow oxygen in acute ischemic stroke...
- Oxygen therapy in chronic obstructive pulmonary diseaseVictor Kim
Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
Proc Am Thorac Soc 5:513-8. 2008..The goals of this article are to briefly describe the indications for chronic oxygen administration, the physiologic effects of treatment, and potential toxicities, as well as its effect on morbidity and mortality...
- Drugs (including oxygen) in severe COPDP Albert
Division of Infection and Immunity, Clinical Sciences Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UK
Eur Respir J 31:1114-24. 2008..Ambulatory oxygen improves exercise capacity, but whether it is used appropriately is in doubt. Overall, short burst oxygen therapy does not offer a benefit and therefore cannot be recommended...
- Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental strokeAneesh B Singhal
Neuroprotection Research Laboratory, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Neurology 58:945-52. 2002..Hyperbaric oxygen therapy is considered an important stroke treatment strategy...
- Ambulatory oxygen therapy, exercise, and survival with advanced chronic obstructive pulmonary disease (the Nocturnal Oxygen Therapy Trial revisited)T L Petty
University of Colorado Health Sciences Center, Denver 80218, USA
Respir Care 45:204-11; discussion 211-3. 2000..In addition, COT was associated with better survival and reduced hospitalizations, compared with NOT patients who were unable to increase their walking level...
- Normobaric hyperoxia delays perfusion/diffusion mismatch evolution, reduces infarct volume, and differentially affects neuronal cell death pathways after suture middle cerebral artery occlusion in ratsNils Henninger
Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
J Cereb Blood Flow Metab 27:1632-42. 2007..Our data suggest that NBO may represent a promising strategy for acute stroke treatment...
- Compliance with LTOT and consumption of mobile oxygenT Ringbaek
Department of Internal Medicine, Bispebjerg Hospital, University of Copenhagen, Denmark
Respir Med 93:333-7. 1999..Using lists referring to the actual usage and discussing the usage with the patients may improve the compliance and cost-benefit...
- Hyperbaric oxygen for acute carbon monoxide poisoningLindell K Weaver
Department of Internal Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, Utah 84143, USA
N Engl J Med 347:1057-67. 2002..Patients with acute carbon monoxide poisoning commonly have cognitive sequelae. We conducted a double-blind, randomized trial to evaluate the effect of hyperbaric-oxygen treatment on such cognitive sequelae...
- Electron paramagnetic resonance-guided normobaric hyperoxia treatment protects the brain by maintaining penumbral oxygenation in a rat model of transient focal cerebral ischemiaShimin Liu
College of Pharmacy, Department of Neurology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131-0001, USA
J Cereb Blood Flow Metab 26:1274-84. 2006..These results suggest that maintaining penumbral oxygenation by normobaric oxygen treatment during ischemia lead to neuroprotection, which is further reflected by the decreased production of ROS, MMP-9, and caspase-8...
- Heliox and oxygen reduce infarct volume in a rat model of focal ischemiaYi Pan
Department of Neurology, Saint Louis University Hospital, 3635 Vista Ave, Saint Louis, MO 63110, USA
Exp Neurol 205:587-90. 2007..This suggests that a greater benefit may accrue from heliox therapy...
- Oxygen therapy in COPD: what do we know?M Bradley Drummond
Am J Respir Crit Care Med 176:321-2. 2007
- Oxygen therapy for patients with COPD: current evidence and the long-term oxygen treatment trialJames K Stoller
Respiratory Institute, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA
Chest 138:179-87. 2010..The trial plans to enroll subjects with COPD with moderate hypoxemia at rest or desaturation with exercise and compare tailored oxygen therapy to no oxygen therapy...
- A cautionary tale about supplemental oxygen: the albatross of neonatal medicineWilliam A Silverman
Pediatrics 113:394-6. 2004
- The effect of different doses of oxygen administration on oxygen saturation in patients with strokeKhalid Ali
Springfield Unit, University Hospital of North Staffordshire, Staffordshire, UK
Neurocrit Care 3:24-6. 2005..The aim of this study was to assess the effects of different doses and routes of oxygen administration on oxygen saturation in patients with stroke...
- Got a match? Home oxygen therapy in current smokersY Lacasse
Thorax 61:374-5. 2006
- Short burst oxygen therapy after activities of daily living in the home in chronic obstructive pulmonary diseaseS J Quantrill
Chest Clinic, Whipps Cross University Hospital, London E11 1NR, UK
Thorax 62:702-5. 2007..Short burst oxygen therapy (SBOT) is widely prescribed in the UK with little evidence of benefit. A study was performed to examine whether SBOT benefits patients when undertaking normal activities at home among those who already use it...
- Predictors of mortality in patients with emphysema and severe airflow obstructionFernando J Martinez
Division of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, MI 48109 0360, and Section of Thoracic Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA
Am J Respir Crit Care Med 173:1326-34. 2006..Limited data exist describing risk factors for mortality in patients having predominantly emphysema...
- Advantages of oxygen inhalation therapy for postoperative pulmonary hypertensionN Ohashi
Department of Pediatrics Developmental Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
Pediatr Cardiol 26:90-2. 2005..remained after surgery, oxygenation was continued for 15 months, which included a shift to at-home oxygen inhalation therapy (HOT)...
- Cost-effectiveness and efficacy in long-term oxygen therapyAnnette Duck
South Manchester University Hospital Trust
Nurs Times 102:46-50. 2006..Annette Duck reviews the use of long-term oxygen therapy and highlights the importance of assessment in selecting both patients and suitable delivery systems...
- Pulmonary hypertension and chronic obstructive pulmonary disease: a case for treatmentTim Higenbottam
Clinical Science, AstraZeneca R and D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, UK
Proc Am Thorac Soc 2:12-9. 2005....
- Hypoxaemia among children in rural hospitals in Papua New Guinea: epidemiology and resource availability--a study to support a national oxygen programmeFrancis Wandi
Department of Paediatrics, Kundiawa Hospital, Simbu Province, Papua New Guinea
Ann Trop Paediatr 26:277-84. 2006....
- Automated adjustment of inspired oxygen in preterm infants with frequent fluctuations in oxygenation: a pilot clinical trialNelson Claure
Division of Neonatology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33101, USA
J Pediatr 155:640-5.e1-2. 2009..To assess the efficacy of a system for automated fraction of inspired oxygen (FiO(2)) adjustment in maintaining oxygen saturation (SpO(2)) within an intended range in preterm infants with spontaneous fluctuations in SpO(2)...
- Long-term morbidity and mortality following hypoxaemic lower respiratory tract infection in Gambian childrenT E West
Medical College of Virginia, Richmond, USA
Bull World Health Organ 77:144-8. 1999..Survival depends more on nutritional status than on having been hypoxaemic. Investment in oxygen therapy appears justified, and efforts should be made to improve nutrition in malnourished children with pneumonia...
- Treatment of respiratory failure in COPDStephan Budweiser
Center for Pneumology, Hospital Donaustauf, Donaustauf, Germany
Int J Chron Obstruct Pulmon Dis 3:605-18. 2008..Such studies might preferentially recruit patients with repeated hypercapnic decompensation or a high risk for death, while ensuring effective ventilation and the patients' adherence to therapy...
- Management of two pregnancies in a woman with mixed connective tissue disease, pulmonary fibrosis, frequent pneumothorax and oxygen inhalation therapy along with a published work reviewTatsuji Hoshino
Department of Obstetrics and Gynecology, Kobe City Medical Center General Hospital, Kobe, Japan
J Obstet Gynaecol Res 34:613-8. 2008Two pregnancies in a woman on oxygen inhalation therapy before pregnancy, due to pulmonary fibrosis and frequent pneumothorax that are secondary to mixed connective tissue disease, were managed safely...
- A randomized controlled trial of the effect of fixed-dose routine nocturnal oxygen supplementation on oxygen saturation in patients with acute strokeChristine Roffe
Stroke Research Group, Keele University, Staffordshire, United Kingdom
J Stroke Cerebrovasc Dis 19:29-35. 2010..The aim of this study was to assess the effect of routine low-flow oxygen supplementation on oxygen saturation (SpO(2)) in patients with acute stroke...
- Oxygen supply in rural africa: a personal experienceG Schneider
Worldwide Evangelisation for Christ International, Banjul, The Gambia
Int J Tuberc Lung Dis 5:524-6. 2001..The system becomes cost effective if a rural hospital needs more than 6 treatment days (1 l/min) of oxygen per month and can be considered in a setting where 6 hours of sunlight per day can be guaranteed...
- Continuous pulse oximetry in acute hemiparetic strokeG Sulter
Department of Neurology, Academisch Ziekenhuis Groningen, Postbus 30 001, 9700 RB, Groningen, The Netherlands
J Neurol Sci 179:65-9. 2000..The aim of this study was to assess the value of early continuous monitoring with pulse oximetry in detecting arterial oxygen desaturations in patients with acute hemiparetic stroke, and the effects of oxygen administration...
- Changes in pulmonary arterial pressure in preterm infants with chronic lung diseaseN V Subhedar
Neonatal Intensive Care Unit, Liverpool Women s Hospital, Crown Street, Liverpool L8 7SS, UK
Arch Dis Child Fetal Neonatal Ed 82:F243-7. 2000..Pulmonary arterial pressure (PAP) is raised in preterm infants with respiratory distress syndrome who subsequently develop chronic lung disease. The natural history of pulmonary hypertension in infants with chronic lung disease is unknown...
- Implementing an oxygen programme in hospitals in Papua New GuineaSens Matai
National Department of Health, School of Medicine and Health Sciences, University of PNG, Papua New Guinea
Ann Trop Paediatr 28:71-8. 2008..The ongoing training of clinical and engineering staff as well as two follow-up evaluations are described...
- A pragmatic assessment of the placement of oxygen when given for exercise induced dyspnoeaJ W Killen
Department of Respiratory Medicine, Freeman Hospital, High Heaton, Newcastle upon Tyne NE7 7DN, UK
Thorax 55:544-6. 2000..It is uncertain whether patients with chronic obstructive pulmonary disease (COPD) given oxygen for symptom relief should be advised to use it before or after exertion...
- Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtableDenis E O'Donnell
Department of Medicine, Queen s University, 102 Stuart Street, Kingston, ON, K7L 2V6 Canada
Proc Am Thorac Soc 4:145-68. 2007..Self-management strategies address the affective aspect of dyspnea and are essential to successful treatment...
- A systematic review of randomized controlled trials examining the short-term benefit of ambulatory oxygen in COPDJudy M Bradley
Department of Respiratory Medicine, Belfast City Hospital, Belfast, Northern Ireland, BT9 7AB
Chest 131:278-85. 2007..Aim: To systematically review the short-term efficacy of ambulatory oxygen from single-assessment studies in COPD...
- Intrapulmonary percussive ventilation in acute exacerbations of COPD patients with mild respiratory acidosis: a randomized controlled trial [ISRCTN17802078]Frederic Vargas
Département de Réanimation Médicale, Hopital Pellegrin Tripode, Bordeaux, France
Crit Care 9:R382-9. 2005....
- Explaining adherence to supplemental oxygen therapy: the patient's perspectiveMark A Earnest
University of Colorado Health Sciences Center, Denver, Colo, USA
J Gen Intern Med 17:749-55. 2002..To describe and explain the patterns of adherence to supplemental oxygen in individuals with hypoxemic chronic obstructive pulmonary disease (COPD)...
- Reducing the frequency and severity of exacerbations of chronic obstructive pulmonary diseasePeter M A Calverley
Department of Medicine, University Hospital Aintree, Clinical Sciences Centre, Longmoor Lane, Liverpool L9 7AL, UK
Proc Am Thorac Soc 1:121-4. 2004..Health status changes mirrored these effects. In summary, combination therapy can effectively prevent exacerbations in patients with more advanced COPD...
- Oxygen therapy for hypercapnic patients with chronic obstructive pulmonary disease and acute respiratory failure: a randomized, controlled pilot studyCharles D Gomersall
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT
Crit Care Med 30:113-6. 2002..A large randomized, controlled study is required to confirm this impression...
- Room-air resuscitation causes less damage to heart and kidney than 100% oxygenMaximo Vento
Neonatal Research Unit, Servicio de Neonatologia, Hospital Universitario Materno Infantil La Fe, Avenida de Campanar 21, 46009 Valencia, Spain
Am J Respir Crit Care Med 172:1393-8. 2005..Pure oxygen causes more oxidative stress than room air in resuscitation of asphyctic neonates, and consequently could be associated with increased tissue damage...
- Histological changes in the alveolar structure of the rat lung after exposure to hyperoxiaMohamed Akram Al-Motabagani
Department of Anatomy, College of Medicine, King Faisal University
Ital J Anat Embryol 110:209-23. 2005..It was concluded that supplemental O2 therapy should be serially monitored by continuous assessment of pulmonary functions...
- Prognostic value of the hematocrit in patients with severe COPD receiving long-term oxygen therapyArnaud Chambellan
Service de Pneumologie, CHU de Nantes, Boulevard Jacques Monod, 44093 Nantes Cedex 1, France
Chest 128:1201-8. 2005..Hematocrit is negatively associated with mortality and morbidity. Whether the association is causative or not and whether or not corrective measures are warranted remain to be determined...
- Effects of maternal hyperoxia with and without normocapnia in uteroplacental and fetal Doppler studiesM J Simchen
Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel
Ultrasound Obstet Gynecol 26:495-9. 2005..We aimed to evaluate the effect of maternal hyperoxygenation with and without maintaining normocapnia on the fetal and uteroplacental circulations in healthy near-term human pregnancies...
- One year period prevalence study of respiratory acidosis in acute exacerbations of COPD: implications for the provision of non-invasive ventilation and oxygen administrationP K Plant
Department of Respiratory Medicine, St James s University Hospital, Leeds LS9 7TF, UK
Thorax 55:550-4. 2000..This study aimed to determine the prevalence of respiratory acidosis in patients admitted with COPD, to draw inferences about oxygen therapy, and to determine the need for NIV services for acute COPD in typical UK hospitals...
- The potential impact of anaemia of chronic disease in COPDT Similowski
Service de Pneumologie, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, and UPRES EA2397 Université Paris VI Pierre et Marie Curie, Paris, France
Eur Respir J 27:390-6. 2006..When this body of knowledge is available, the question of the putative benefits of raising haemoglobinaemia in chronic obstructive pulmonary disease will have to be addressed...
- Overnight prescription of oxygen in long term oxygen therapy: time to reconsider the guidelines?M Nisbet
Green Lane Respiratory Services, Auckland City Hospital, University of Auckland, Auckland, New Zealand
Thorax 61:779-82. 2006....
- Recently published papers: the Jekyll and Hyde of oxygen, neuromuscular blockade and good vibrations?Jonathan Ball
General Intensive Care Unit, St George s Hospital, Blackshaw Road, London, UK
Crit Care 11:108. 2007..This issue's recently published papers commentary takes a long hard look at the surprisingly topically issue of oxygen. To give a balanced perspective, topical ventilatory studies are also discussed...
- [Clinical and transcutaneous oxygen saturation characteristics in hospitalized infants with acute viral bronchiolitis]Fernanda M Rubin
Pediatria, Universidade Federal do Rio Grande do Sul
J Pediatr (Rio J) 79:435-42. 2003..To describe the clinical characteristics of infants with acute viral bronchiolitis (AVB) and to assess the influence of oxygen desaturation time (DT) as a prognostic test to estimate the evolution of such patients...
- Influence of the oxygen delivery system on the quality of life of patients with chronic hypoxemiaSuzana Erico Tanni
Pulmonology Division, Universidade Estadual Paulista UNESP, State University of São Paulo Julio de Mesquita Filho School of Medicine of Botucatu, Botucatu, SP, Brasil
J Bras Pneumol 33:161-7. 2007....
- Helium/oxygen mixture reduces the work of breathing at the end of the weaning process in patients with severe chronic obstructive pulmonary diseaseJean-Luc Diehl
, , France
Crit Care Med 31:1415-20. 2003....
- Diagnostic delays and mis-management in cluster headacheA Bahra
Headache Group, Institute of Neurology, Queen Square, London, UK
Acta Neurol Scand 109:175-9. 2004..Cluster headache is a stereotyped form of primary headache that while common in terms of neurologic illnesses is much less common as a cause of disabling headache than migraine...
- Impact of noninvasive home ventilation on long-term survival in chronic hypercapnic COPD: a prospective observational studyS Budweiser
Center for Pneumology, Hospital Donaustauf, Donaustauf, Germany
Int J Clin Pract 61:1516-22. 2007..The long-term benefit from noninvasive ventilation (NIV) in chronic hypercapnic chronic obstructive pulmonary disease (COPD) remains uncertain...
- Oxidative stress in asphyxiated term infants resuscitated with 100% oxygenMaximo Vento
School of Medicine, University of Alicante, Department of Pediatrics and Neonatology and Division of Neonatology, Hospital Virgen del Consuelo, Valencia, Spain
J Pediatr 142:240-6. 2003..Assays performed included: blood gases; reduced glutathione (GSH) and oxidized glutathione (GSSG) in whole blood; glutathione-related enzyme activities; and superoxide dismutase activity (SOD) in erythrocytes...
- Benefits of supplemental oxygen in exercise training in nonhypoxemic chronic obstructive pulmonary disease patientsMargareta Emtner
Rehabilitation Clinical Trials Center, Harbor-UCLA Research and Education Institute, Torrance, CA 90502, USA
Am J Respir Crit Care Med 168:1034-42. 2003..001). We conclude that supplemental oxygen provided during high-intensity training yields higher training intensity and evidence of gains in exercise tolerance in laboratory testing...
- Helium-oxygen versus air-oxygen noninvasive pressure support in decompensated chronic obstructive disease: A prospective, multicenter studyPhilippe Jolliet
Medical Intensive Care Division, University Hospital, Geneva, Switzerland
Crit Care Med 31:878-84. 2003..He/oxygen NIPSV can be safely administered and could prove to be a cost-effective strategy...
- Oximetry feedback flow control simulation for oxygen therapyMario G Iobbi
Department of Bioengineering, South Kensington Campus, Imperial College London, London, SW7 2AZ, UK
J Clin Monit Comput 21:115-23. 2007..Using a closed-loop controller, we have evaluated a simulated method to automatically regulate the oxygen flow-rate in response to the measured oxygen demand...
- Near-infrared spectroscopy in the detection of regional tissue oxygenation during hypoxic events in preterm infants undergoing critical careAnna Petrova
Division of Neonatology, Department of Pediatrics, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Pediatr Crit Care Med 7:449-54. 2006....
- Non-invasive ventilation in COPD 1: Managing exacerbationsDonna Barnes
Pilgrims Hospice, Canterbury
Nurs Times 103:26-7. 2007..Part 1 examines how an exacerbation of COPD can lead to hypercapnic respiratory failure and how this might be managed...
- Oxygen supplementation increases glucose tolerance during euglycaemic hyperinsulinaemic glucose clamp procedure in patients with severe COPD and chronic hypoxaemiaP Jakobsson
Department of Pulmonary Medicine, University Hospital, Linkoping, Sweden
Clin Physiol Funct Imaging 26:271-4. 2006..03) with oxygen supplementation. The results indicate that normalization of oxygen saturation in COPD patients with chronic hypoxaemia may have an immediate effect on glucose tolerance and tissue sensitivity to insulin in these patients...
- Infants with bronchopulmonary dysplasia suckle with weak pressures to maintain breathing during feedingKatsumi Mizuno
Showa University of Medicine, Department of Pediatrics, 1 5 8 Hatanodai, Shinagawa ku, Tokyo 142 8666, Japan
Pediatrics 120:e1035-42. 2007..The aim of this study was to determine whether the severity of bronchopulmonary dysplasia affects not only coordination among suck-swallow-respiration but also sucking endurance and performance itself...
- Oxygen as a neonatal health hazard: call for détente in clinical practiceAugusto Sola
Mid Atlantic Neonatology Associates and Morristown Memorial Hospital, Morristown, NJ, USA
Acta Paediatr 96:801-12. 2007..Neonatal exposure to pure O2, even if brief, or to pulse oximetry >95% when breathing supplemental O2 must be avoided as much as possible...
- Respiratory assessment in adultsT Moore
School of Health and Social Sciences, Middlesex University, Middlesex
Nurs Stand 21:48-56; quiz 58. 2007..This article highlights the role of the nurse in respiratory assessment and discusses the implications of clinical findings...
- Influence of cardiac output level on oxygen exchange in chronic obstructive pulmonary disease patientsGérard Manier
Service des Explorations Fonctionnelles Respiratoires, Hopital Pellegrin, Bordeaux Cedex, France chu bordeaux fr
Clin Physiol Funct Imaging 26:275-82. 2006..The aim of the present study was to evaluate the influence of cardiac output (CO) level observed at rest in COPD patients on interaction between central and peripheral O(2) exchange...
- Optimum oxygen therapy in preterm babiesW Tin
Directorate of Neonatal Medicine, The James Cook University Hospital, Middlesbrough, Cleveland, UK
Arch Dis Child Fetal Neonatal Ed 92:F143-7. 2007....
- Comparison of six-minute walking tests conducted with and without supplemental oxygen in patients with chronic obstructive pulmonary disease and exercise-induced oxygen desaturationSevgi Ozalevli
Doluz Eylul University, School of Physical Therapy and Rehabillitation, Izmir, Turkey
Ann Saudi Med 27:94-100. 2007....
- Sleeping position, oxygen saturation and lung volume in convalescent, prematurely born infantsZainab Kassim
Children Nationwide Regional Neonatal Intensive Care Centre, 4th Floor, Golden Jubilee Wing, King s College Hospital, London SE5 9PJ, UK
Arch Dis Child Fetal Neonatal Ed 92:F347-50. 2007..To determine whether the effects of sleeping position on lung volume and oxygenation are influenced by postmenstrual age (PMA) and oxygen dependency in convalescent prematurely born infants...
- Expedited oxygen wean after coil embolization of systemic-to-pulmonary collaterals in a premature infant with bronchopulmonary dysplasiaWilliam N Evans
Children's Heart Center, 3006 S Maryland Pkwy, Suite 690, Las Vegas, NV 89109, USA
J Ultrasound Med 26:695-7. 2007
- Lower oxygen saturation alarm limits decrease the severity of retinopathy of prematurityDeborah K Vanderveen
Department of Ophthalmology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
J AAPOS 10:445-8. 2006..To determine whether lowering oxygen saturation alarm limits for infants at risk for retinopathy of prematurity (ROP) reduces its incidence and/or severity...
- Achievement of targeted saturation values in extremely low gestational age neonates resuscitated with low or high oxygen concentrations: a prospective, randomized trialRaquel Escrig
Neonatalogy Service, La Fe Infant Maternal University Hospital, Valencia, Spain
Pediatrics 121:875-81. 2008....
- Oxygen - elixir of life or Trojan horse? Part 2: oxygen and neonatal anesthesiaJohan van der Walt
Paediatr Anaesth 16:1205-12. 2006
- The effect of bronchodilators and oxygen alone and in combination on self-paced exercise performance in stable COPDAlberto Cukier
Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
Respir Med 101:746-53. 2007..Clinically relevant improvement is possible when therapies with a different mechanism of action are combined...
- Approach to respiratory failure in emergency departmentP Forte
Department of Emergency Medicine, Catholic University, Rome, Italy
Eur Rev Med Pharmacol Sci 10:135-51. 2006..This kind of ventilation was firsthy applied in intensive Care and in Respiratory Care Unit. Randomized controlled clinical trials have showed its usefulness in the early treatment of several forms of ARF, together with medical therapy...
- Optimal oxygen therapy in the newborn periodOla Didrik Saugstad
Department of Pediatric Research, National Hospital, University of Oslo, Oslo, Norway
Pediatr Pulmonol Suppl 26:112-3. 2004
- Home oxygen therapy: the jury is still in sessionAnn C Halbower
J Perinatol 24:59-61. 2004
- [Management of patients with stable COPD]Hideo Toyoshima
Department of Respiratory Medicine, School of Medicine, Fukuoka University
Nippon Rinsho 61:2163-9. 2003..Pulmonary rehabilitation is useful for patients with all severity to reduce symptoms and to improve quality of life. Selected patients can take beneficial effect by long-term oxygen therapy, ventilatory support and surgical treatment...
- Contemporary management of chronic obstructive pulmonary disease: scientific reviewDon D Sin
Division of Pulmonary Medicine, University of Alberta, Edmonton, Canada
JAMA 290:2301-12. 2003..The care of patients with chronic obstructive pulmonary disease (COPD) has changed radically over the past 2 decades, and novel therapies can not only improve the health status of patients with COPD but also modify its natural course...
- Treatment of chronic obstructive pulmonary diseaseIrwin Ziment
Department of Medicine, Olive View Medical Center, Sylmar, California 91342-1495, USA
J Am Med Dir Assoc 4:S121-6. 2003
- Closed-loop control if the inspired fraction of oxygen in mechanical ventilationFleur Tehrani
Department of Electrical Engineering, California State University, Fullerton, California 92834 6870, USA
J Clin Monit Comput 17:367-76. 2002..More specifically, the aim of the study was to assess the robustness of the controller in correcting hypoxemia as well as its effectiveness in prevention of hyperoxemia and oxygen toxicity...
- Management of acute exacerbations of chronic obstructive pulmonary diseaseJ D Adkison
Department of Clinical Sciences and Administration, University of Houston, College of Pharmacy, TX 77030, USA
Pharmacotherapy 21:929-39. 2001..Many exacerbations may be caused by viruses or noninfective sources, in which case antibiotics are not indicated. Oxygen administration with or without assisted ventilation may be required for short-term management...
- [Noninvasive intermittent self ventilation in chronic respiratory insufficiency]O Karg
Klinik für Intensivmedizin und Langzeitbeatmung, Asklepios Fachkliniken, München Gauting
Internist (Berl) 44:69-77; quiz 78-9. 2003..The most frequent indications for home mechanical ventilation are diseases with restrictive ventilatory defects, especially chest wall disorders and neuromuscular disorders...
- Systematic review of the role of pre-oxygenation for tracheal suctioning in ventilated newborn infantsM A Pritchard
Perinatal Research Centre, Royal Women s Hospital, The University of Queensland, Herston, Australia
J Paediatr Child Health 39:163-5. 2003..In the present systematic review the evidence to support its use is discussed and the authors conclude that no confident recommendations can be made from the results of this review...
- The controversies surrounding oxygen therapy in neonatal intensive care unitsSunil K Sinha
The James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, United Kingdom
Curr Opin Pediatr 15:161-5. 2003....
- Safety and efficacy of nitric oxide in chronic lung diseaseP L Clark
Section of Neonatology, Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
Arch Dis Child Fetal Neonatal Ed 86:F41-5. 2002..Four infants died. CONCLUSION: INO (< or = 20 ppm) improved oxygenation in most infants with early CLD, without inducing changes in markers of inflammatory or oxidative injury...
- Noninvasive ventilation with helium-oxygen rather than air-oxygen in acute exacerbations of chronic obstructive disease?Gilles Hilbert
Crit Care Med 31:990-1. 2003
- Are COPD patients with nocturnal REM sleep-related desaturations more prone to developing chronic respiratory failure requiring long-term oxygen therapy?Margherita Sergi
Respiratory Function Laboratory, S Maugeri Foundation, Montescano Medical Center, I 27040 Montescano PV, Italy
Respiration 69:117-22. 2002..Nocturnal oxygen desaturations (NOD), especially during REM sleep, have been described in patients with COPD. However, the role of NOD in the evolution of COPD to chronic respiratory failure has not been well studied...
- Oxygen monitoring in preterm babies: too high, too low?Win Tin
Department of Paediatrics and Neonatal Medicine, The James Cook University Hospital, Middlesbrough, UK
Paediatr Respir Rev 4:9-14. 2003..This is particularly important in babies of less than 28 weeks' gestation, who currently remain at serious risk of chronic lung disease and permanent retinal damage...
- [Nocturnal desaturation in chronic obstructive pulmonary disease]Bruno Sposato
Centro Universitario Broncopneumopatie Emergenti, Ospedale Forlanini, Universita La Sapienza, Roma
Recenti Prog Med 93:686-94. 2002..Since negative outcomes are possible, nocturnal oxygen desaturation must be early put in evidence and then treated with suitable drugs, correct dietetic regimen, respiratory physiotherapy and nocturnal oxygen-therapy...
- Respiratory changes during defecation in patients with chronic respiratory failureM Delmastro
Respiratory Unit, Fondazione S. Maugeri, Istituto Scientifico di Pavia, IRCSS, Pavia, Italy
Eur Respir J 23:617-9. 2004..In conclusion, the respiratory system of patients with chronic respiratory failure may be significantly strained by defecation...
- [A comparison of the effects of 50 % oxygen combined with CPAP to the non-ventilated lung vs. 100 % oxygen on oxygenation during one-lung ventilation]M Senturk
Abteilung für Anästhesiologie, Istanbul Universität, Medizinische Fakultat, Istanbul
Anasthesiol Intensivmed Notfallmed Schmerzther 39:360-4. 2004..In a prospective, randomised, double-blind study the effects of FiO (2) of 0,5 with CPAP and a FiO (2) of 1.0 without CPAP on oxygenation and pulmonary shunt during one-lung ventilation (OLV) were examined...
- Automatic control of the inspired oxygen fraction in preterm infants: a randomized crossover trialMichael S Urschitz
Department of Neonatology, Tuebingen University Hospital, Tuebingen, Germany
Am J Respir Crit Care Med 170:1095-100. 2004..001). Automatic oxygen control may optimize oxygen administration to preterm infants receiving nasal continuous positive airway pressure and reduce nursing time spent with oxygen control...
- Reduction of hyperinflation by pharmacologic and other interventionsRichard Casaburi
Rehabilitation Clinical Trials Center, Los Angeles Biomedical Research Institute at Harbor University of California at Los Angeles Medical Center, Torrance, California 90502, USA
Proc Am Thorac Soc 3:185-9. 2006..With a firm understanding of the physiologic basis of exercise limitation, we can focus on defining new and better strategies to improve exercise tolerance...
- COPD: current therapeutic interventions and future approachesP J Barnes
National Heart and Lung Institute, Imperial College School of Medicine, Dovehouse St, London SW3 6LY, UK
Eur Respir J 25:1084-106. 2005..More research is needed to understand the cellular and molecular mechanisms of chronic obstructive pulmonary disease and to develop biomarkers and monitoring techniques to aid the development of new therapies...
Research Grants120 found, 100 shown here
- MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITSNeil Finer; Fiscal Year: 2007..abstract_text> ..
- MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITSNeil Finer; Fiscal Year: 2005..abstract_text> ..
- Strategies to Prevent COPD ExacerbationFernando Martinez; Fiscal Year: 2007..abstract_text> ..
- Rapid Clinical Snapshots from the EMR among Pneumonia PatientsGabriel J Escobar; Fiscal Year: 2010....
- HOW MUCH DOES SHE REALLY DRINK? AN HMO INTERVENTIONGABRIEL ESCOBAR; Fiscal Year: 2003..abstract_text> ..
- Novel Therapeutic Approaches in IPFFernando Martinez; Fiscal Year: 2007..These protocols will define the role of standard therapy, test the efficacy of targeted combination therapy, and explore the promise of a novel approach to the design and delivery of therapeutic agents for IPF. (End of Abstract) ..
- NICHD Cooperative Multicenter Neonatal Research NetworkMichele Walsh; Fiscal Year: 2007....
- Strategies to Improve COPD ManagementRichard Casaburi; Fiscal Year: 2007..These studies should have immediate impact on treatment strategies for large poor-prognosis subgroups of COPD patients. ..
- DETERMINANTS OF EXACERBATION FREQUENCY IN PATIENTS WITH*Jadwiga Wedzicha; Fiscal Year: 2007..abstract_text> ..
- Normobaric Hyperoxia in Acute Ischemic StrokeAneesh B Singhal; Fiscal Year: 2010..Breathing high-flow oxygen may prove to be a simple, practical, portable, and potentially cost-effective therapy that improves stroke outcomes, either independently or by extending the time window for IV tPA. ..
- Rapid Clinical Snapshots from the EMR among Pneumonia PatientsGABRIEL ESCOBAR; Fiscal Year: 2009....
- Normobaric Hyperoxia in Acute Ischemic StrokeAneesh Singhal; Fiscal Year: 2007..Breathing high-flow oxygen may prove to be a simple, practical, portable, and potentially cost-effective therapy that improves stroke outcomes, either independently or by extending the time window for IV tPA. ..
- Novel Therapies in Idiopathic Pulmonary FibrosisFernando Martinez; Fiscal Year: 2007..This will become particularly important if translational research is to keep pace as strides are made in the basic immunology, genetics and biochemistry of IPF. ..
- Sepsis and Critical Illness in Babies > 34 Weeks GestationGABRIEL ESCOBAR; Fiscal Year: 2007..Our project builds on considerable development work conducted by investigators at Kaiser Permanente's Division of Research, the University of California, San Francisco, and the Harvard Newborn Medicine Program. ..
- Normobaric Hyperoxia in Acute Ischemic StrokeAneesh Singhal; Fiscal Year: 2009..Breathing high-flow oxygen may prove to be a simple, practical, portable, and potentially cost-effective therapy that improves stroke outcomes, either independently or by extending the time window for IV tPA. ..
- Postnatal Consequences of Fetal InflammationAlan Jobe; Fiscal Year: 2007..This research will use clinically relevant prenatal exposures and postnatal sensitization to establish under controlled conditions any link between antenatal inflammation and the hygiene hypothesis. ..
- Improving Physician Skill at Providing End-of-Life CareJ Curtis; Fiscal Year: 2004..The results will allow investigators and others to develop targeted educational and systemic interventions to improve the quality of this care. ..
- GERIATRIC CLINICAL EPIDEMIOLOGY TRAINING GRANTSTEVEN HALBERT; Fiscal Year: 2007..g., clinical trials, case control, cohort research, etc.), and the faculties' commitment to collaborative research. ..
- Reducing Mortality from Acute Hemorrhage in TraumaJohn Hess; Fiscal Year: 2006..Reducing death from acute hemorrhage in trauma care will be a major step forward in reducing overall trauma mortality. ..
- COGNITIVE EFFECTS OF LUNG VOLUME REDUCTION SURGERYElizabeth Kozora; Fiscal Year: 2004..Forty normal controls will be tested at baseline and 6-10 weeks follow- up. ..
- PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-IIJOHN WEG; Fiscal Year: 2003..of lives lost from underdiagnosis, and major bleeding from overdiagnosis; 2) the potential applicability of a OF A NEW TECHNOLOGY FOR THE DIAGNOSIS OF PE THAT WILL HAVE WIDESPREAD AVAILABILITY; AND 3) THE INVESTIGATION ..
- Methylphenidate for Fatigue in Advanced Cancer PatientsEduardo Bruera; Fiscal Year: 2009....
- Angiogenic Agents and Alveolar InjuryVineet Bhandari; Fiscal Year: 2007..Determine the differences and the degree to which the response to hyperoxia-induced acute lung injury differs in adult, newborn and fetal mice with regard to VEGF, Angiopoietin 1 and Angiopoietin 2. ..
- TRANSFORMING GROWTH FACTOR - BETA MEDIATES EFFECTS OF HYPOXIA IN NEWBORN LUNGNamasivayam Ambalavanan; Fiscal Year: 2010....
- MR Spectroscopy of SIV Brain InjuryRamon Gonzalez; Fiscal Year: 2009..Specific Aim 2. Determine the severity of CNS injury by in vivo & ex vivo MRS and immunohistochemistry in different brain regions, and determine the levels of perivascular MPs in those regions. ..
- ANTECEDENTS TO LUNG INJURY IN THE PRETERMAlan Jobe; Fiscal Year: 2005..Finally, the ventilation and surfactant strategies that are found to cause the least injury will be tested to see if the arrest in lung development can be prevented. ..
- Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB InfectionsLisa Maragakis; Fiscal Year: 2007..This research is designed to better understand how providers use information from various microbiology laboratory testing methods to choose treatments and to identify strategies that lead to the best patient outcomes. ..
- Role of Angiogenic Agents in Alveolar Maturation and InjuryVineet Bhandari; Fiscal Year: 2010....
- TRANSFORMING GROWTH FACTOR - BETA MEDIATES EFFECTS OF HYPOXIA IN NEWBORN LUNGNamasivayam Ambalavanan; Fiscal Year: 2009....
- Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB InfectionsLisa Maragakis; Fiscal Year: 2009..This research is designed to better understand how providers use information from various microbiology laboratory testing methods to choose treatments and to identify strategies that lead to the best patient outcomes. ..
- C1q-complement and hypoxic-ischemic injury in the developing brain.Vadim S Ten; Fiscal Year: 2010....
- School-Based Asthma Therapy: Stage 2 Effectiveness Study RevisedJill Halterman; Fiscal Year: 2009..Should it prove successful in reducing symptoms and improving the health of young urban children with asthma, it has the potential to serve as a model for improved asthma care in urban communities. ..
- C1q-complement and hypoxic-ischemic injury in the developing brain.VADIM TEN; Fiscal Year: 2007....
- PREDICTING BRAIN TUMOR CHEMOSENSITIVITY BY IN VIVO MRSRamon Gonzalez; Fiscal Year: 2002..abstract_text> ..
- MOLECULAR NEUROIMAGING OF AIDS DEMENTIA--ANIMAL MODELSRamon Gonzalez; Fiscal Year: 2002..The relationship of viral infection in the brain to metabolic and pathological abnormalities subsequently observed will be determined. ..
- PATHOPHYSIOLOGY OF EXERCISE INDUCED ASTHMAEDWARD MCFADDEN; Fiscal Year: 2003..abstract_text> ..
- School-Based Asthma Therapy: Stage 2 Effectiveness StudyJill Halterman; Fiscal Year: 2007..Should it prove successful in reducing symptoms and improving the health of young urban children with asthma, it has the potential to serve as a model for improved asthma care in urban communities. ..
- Oxygen, Oxidant Stress and Wheezing in Premature InfantsTimothy Stevens; Fiscal Year: 2007..By evaluating the effect of oxygen exposure on oxidant stress and airway dysfunction this award will identify new therapeutic approaches to improve respiratory health of preterm infants in early childhood. ..
- MMP-2 in Neonatal Hypoxic Pulmonary Vascular RemodelingNamasivayam Ambalavanan; Fiscal Year: 2007..Determination of the mechanisms of ECM protein deposition in the neonatal pulmonary vasculature will provide essential information on normal pulmonary vascular development and lead to the development of new therapies for HPVR. ..
- C-Reactive Protein in Extremely Low Birth Weight NeonatesNamasivayam Ambalavanan; Fiscal Year: 2007....
- Prevention of Healthcare-Associated Drug-Resistant GNRLisa Maragakis; Fiscal Year: 2006..Maragakis with the skills she needs to develop into an independent clinical investigator in epidemiologic research for the prevention of healthcare-associated infections. ..