Research Topics
| extracorporeal membrane oxygenationSummarySummary: Application of a life support system that circulates the blood through an oxygenating system, which may consist of a pump, a membrane oxygenator, and a heat exchanger. Examples of its use are to assist victims of smoke inhalation injury, respiratory failure, and cardiac failure. Top Publications
Research Grants
| Scientific Experts
|
Detail Information
Publications
Pulsatile ECMO in neonates and infants: first European clinical experience with a new deviceSalvatore Agati
Pediatric Cardiac Surgery Unit, San Vincenzo Hospital, 98039 Taormina, Messina, Italy
ASAIO J 51:508-12. 2005..During this period, 10 patients required extracorporeal membrane oxygenation (ECMO) support for acute postcardiotomy heart failure...
A simplified and economic technique for immediate postcardiotomy pediatric extracorporeal membrane oxygenationChristian Kreutzer
Division of Cardiovascular Surgery, Ricardo Gutierrez Children s Hospital, MD Gallo 1330, 1425 Buenos Aires, Argentina
ASAIO J 51:659-62. 2005We report a simplified modification of the cardiopulmonary bypass (CPB) circuit to create a closed extracorporeal membrane oxygenation (ECMO) circuit for short-term cardiac support...
Extracorporeal membrane oxygenation in adults with severe respiratory failure: a multi-center databaseThomas V Brogan
Division of Critical Care Medicine, Department of Pediatrics, Seattle Children s Hospital, University of Washington School of Medicine, Seattle, WA, USA
Intensive Care Med 35:2105-14. 2009To evaluate clinical and treatment factors for patients recorded in the Extracorporeal Life Support Organization (ELSO) registry and survival of adult extracorporeal membrane oxygenation (ECMO) respiratory failure patients.
Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress SyndromeAndrew Davies
FRACP, FJFICM, Intensive Care Unit, Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia
JAMA 302:1888-95. 2009..It caused an epidemic of critical illness and some patients developed severe acute respiratory distress syndrome (ARDS) and were treated with extracorporeal membrane oxygenation (ECMO).
Plasma concentrations of oseltamivir and oseltamivir carboxylate in critically ill children on extracorporeal membrane oxygenation supportEnno D Wildschut
Intensive Care and Department of Paediatric Surgery, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
PLoS ONE 5:e10938. 2010To evaluate the effect of extracorporeal membrane oxygenation (ECMO) support on pharmacokinetics of oseltamivir and oseltamivir carboxylate (OC) in children.
A systematic review to inform institutional decisions about the use of extracorporeal membrane oxygenation during the H1N1 influenza pandemicMatthew D Mitchell
Center for Evidence Based Practice, University of Pennsylvania Health System, Philadelphia, PA, USA
Crit Care Med 38:1398-404. 2010To systematically evaluate the effect of extracorporeal membrane oxygenation on survival in adults with acute respiratory failure and to help inform institutional decisions about implementing an extracorporeal membrane oxygenation ..
Fulminant peripartum cardiomyopathy rescue with extracorporeal membranous oxygenationI J Smith
Department of Cardiothoracic, Auckland City Hospital, Grafton, Auckland, New Zealand
Int J Obstet Anesth 18:186-8. 2009..This case highlights the potential of this lifesaving treatment, in appropriately selected patients, where death seems inevitable. No major complications of extracorporeal membranous oxygenation occurred in this patient...
Temporary extracorporeal membrane oxygenation in the treatment of acute traumatic lung injuryW Voelckel
Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria
Can J Anaesth 45:1097-102. 1998..To report two cases of acute life-threatening traumatic lung injury, who required temporary extracorporeal veno-venous membrane oxygenation (ECMO), and airlifting to a level I trauma centre...
Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trialGiles J Peek
Department of Cardiothoracic Surgery, Glenfield Hospital, Leicester, UK
Lancet 374:1351-63. 2009..We aimed to delineate the safety, clinical efficacy, and cost-effectiveness of extracorporeal membrane oxygenation (ECMO) compared with conventional ventilation support.
Outcomes and long-term quality-of-life of patients supported by extracorporeal membrane oxygenation for refractory cardiogenic shockAlain Combes
Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6, Paris, France
Crit Care Med 36:1404-11. 2008To assess the outcomes and long-term quality-of-life of patients supported by extracorporeal membrane oxygenation (ECMO) for refractory cardiogenic shock.
Inter-hospital transportation of patients with severe acute respiratory failure on extracorporeal membrane oxygenation--national and international experienceV Linden
Department of Pediatric Anesthesiology and Intensive Care, Astrid Lindgren Children s Hospital, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
Intensive Care Med 27:1643-8. 2001To evaluate the experiences and results from inter-hospital transportation of patients with acute respiratory failure on extracorporeal membrane oxygenation (ECMO).
Transportation of critically ill patients on extracorporeal membrane oxygenationK Wagner
Department of Anesthesiology and Intensive Care Medicine, Rikshospitalet University Hospital, Oslo, Norway
Perfusion 23:101-6. 2008Serious pulmonary and cardiac failure may be treated with extracorporeal membrane oxygenation (ECMO) when conventional treatment fails...
Recovery of multipotent progenitors from the peripheral blood of patients requiring extracorporeal membrane oxygenation supportKim Chi T Bui
Mattel Children s Hospital at UCLA Medical Center, David Geffen School of Medicine, Los Angeles, CA, USA
Am J Respir Crit Care Med 181:226-37. 2010..We hypothesize that marrow progenitors are mobilized into the circulation of patients with cardiac and/or respiratory failure, and may then traffic to and incorporate into the sites of tissue injury...
Improved survival after cardiac arrest using emergent autopriming percutaneous cardiopulmonary supportKiick Sung
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Kangnam-ku, Seoul, Korea
Ann Thorac Surg 82:651-6. 2006..CONCLUSIONS: The use of preassembled, heparin-coated and autoprimed devices enabled us to rescue in-hospital cardiac arrest patients who might have died without this procedure...
Switch from venoarterial extracorporeal membrane oxygenation to arteriovenous pumpless extracorporeal lung assistBernhard Floerchinger
Department of Cardiothoracic Surgery, University Hospital of Regensburg, Regensburg, Germany
Ann Thorac Surg 89:125-31. 2010b>Extracorporeal membrane oxygenation is an effective rescue tool to treat cardiopulmonary failure. Pumpless systems treat lung failure only; they require adequate cardiac output.
Early and late outcomes of 517 consecutive adult patients treated with extracorporeal membrane oxygenation for refractory postcardiotomy cardiogenic shockArdawan Julian Rastan
Department of Cardiac Surgery, Heart Center, University of Leipzig, Leipzig, Germany
J Thorac Cardiovasc Surg 139:302-11, 311.e1. 2010..5% to 1.5% of cases. Risk factors influencing early or long-term outcome after extracorporeal membrane oxygenation implantation are not well described.
Extracorporeal membrane oxygenation for primary graft dysfunction after lung transplantation: long-term survivalChristian A Bermudez
Division of Cardiothoracic Surgery, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Ann Thorac Surg 87:854-60. 2009..Venovenous or venoarterial extracorporeal membrane oxygenation (ECMO) allows lung recovery; however, the optimal approach and impact on long-term survival are ..
Extracorporeal circulatory systems in the interhospital transfer of critically ill patients: experience of a single institutionAssad Haneya
Department of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany
Ann Saudi Med 29:110-4. 2009..Extracorporeal heart and lung assist systems are increasingly used as a bridge to end-organ recovery or transplantation, and as an ultimate rescue tool in cardiopulmonary resuscitation...
Percutaneous left ventricular "vent" insertion for left heart decompression during extracorporeal membrane oxygenationMichael M H Cheung
Cardiothoracic Unit, Great Ormond Street Hospital, London, UK
Pediatr Crit Care Med 4:447-9. 2003..CONCLUSIONS: In patients at high risk of bleeding, a percutaneous technique may be useful for left ventricular decompression...
Extracorporeal membrane oxygenation to support adult patients with cardiac failure: predictive factors of 30-day mortalityFrancesco Formica
Cardiac Surgery Clinic, Department of Surgical Science, University of Milano Bicocca, San Gerardo Hospital, Monza, Italy
Interact Cardiovasc Thorac Surg 10:721-6. 2010Adult patients supported on extracorporeal membrane oxygenation (ECMO) are very sick and many complications are often present in each single patient; therefore, it is not always easy to find some risk factors that can predict the early ..
Extracorporeal oxygenation support for curative surgery in a patient with papillary thyroid carcinoma invading the tracheaH K Jeon
Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
J Laryngol Otol 123:807-10. 2009..This approach facilitated curative surgery in a patient with papillary thyroid carcinoma invading the trachea...
Anticoagulation and coagulation management for ECMOWilliam C Oliver
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Semin Cardiothorac Vasc Anesth 13:154-75. 2009Advances in extracorporeal membrane oxygenation (ECMO) management have helped to reduce complications compared with its inception but they remain high. The principal causes of mortality and morbidity are bleeding and thrombosis...
Minimally invasive left-heart decompression during venoarterial extracorporeal membrane oxygenation: an alternative to a percutaneous approachMina Guirgis
Institute of Cardiovascular Sciences, St Boniface Research Centre, Winnipeg, Manitoba, Canada
Interact Cardiovasc Thorac Surg 10:672-4. 2010Decompression of the left-heart following initiation of extracorporeal membrane oxygenation, is at times required. In the setting of a closed chest this can present a challenge...
Peripheral extracorporeal membrane oxygenation (ECMO) in patients with posttransplant cardiac graft failureP Leprince
Cardiothoracic Surgery Department, La Pitie Salpetriere Hospital, Paris, France
Transplant Proc 37:2879-80. 2005We sought to report the usefulness of extracorporeal membrane oxygenation (ECMO) in heart transplant patients.
Extracorporeal membrane oxygenation for the support of infants, children, and young adults with acute myocarditis: a review of the Extracorporeal Life Support Organization registrySatish K Rajagopal
Department of Cardiology, Children s Hospital Boston, Boston, MA, USA
Crit Care Med 38:382-7. 2010To describe survival outcomes for pediatric patients supported with extracorporeal membrane oxygenation for severe myocarditis and identify risk factors for in-hospital mortality.
Temporary circulatory support with extra corporeal membrane oxygenation in adults with refractory cardiogenic shockH Liden
Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Scand Cardiovasc J 43:226-32. 2009..Treatment with mechanical assist devices is complicated and expensive but claim to improve survival. We reviewed our experience of venoarterial extracorporeal membrane oxygenation (ECMO) in patients with acute cardiogenic shock.
Extracorporeal membrane oxygenation to support cardiopulmonary resuscitation in adultsRavi R Thiagarajan
Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Ann Thorac Surg 87:778-85. 2009b>Extracorporeal membrane oxygenation (ECMO) to support cardiopulmonary resuscitation (CPR) has been shown to improve survival in children and adults...
Extracorporeal membrane oxygenation for nonneonatal acute respiratory failure: the Massachusetts General Hospital experience from 1990 to 2008Deepika Nehra
Division of Pediatric Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Arch Surg 144:427-32; discussion 432. 2009To determine the efficacy of extracorporeal membrane oxygenation (ECMO) for nonneonatal acute respiratory failure.
Traumatic lung injury treated by extracorporeal membrane oxygenation (ECMO)J A Cordell-Smith
Heartlink ECMO Centre, The Glenfield Hospital, Groby Road, Leicester LE3 9QP, UK
Injury 37:29-32. 2006..b>Extracorporeal membrane oxygenation (ECMO) has been used successfully in critically ill adult trauma patients and can offer an ..
Extracorporeal membrane oxygenation is superior to right ventricular assist device for acute right ventricular failure after heart transplantationShahrokh Taghavi
Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
Ann Thorac Surg 78:1644-9. 2004..The aim of this retrospective study was to investigate the effectiveness of two different mechanical circulatory support systems for this indication...
Successful treatment of peripartum cardiomyopathy with extracorporeal membrane oxygenationD A Palanzo
Heart and Vascular Institute, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania 17033, USA
Perfusion 24:75-9. 2009..She was discharged one month after her admission. The new technology available allows for ECMO to be considered as an earlier option for the treatment and management of these patients as a bridge to recovery...
Acute kidney injury in adult postcardiotomy patients with extracorporeal membrane oxygenation: evaluation of the RIFLE classification and the Acute Kidney Injury Network criteriaXiaolei Yan
Intensive Care Unit, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, PR China
Eur J Cardiothorac Surg 37:334-8. 2010Acute kidney injury (AKI) is one of the major complications in adult postcardiotomy patients on extracorporeal membrane oxygenation (ECMO) support...
Follow-up study of adolescents exposed to di(2-ethylhexyl) phthalate (DEHP) as neonates on extracorporeal membrane oxygenation (ECMO) supportKhodayar Rais-Bahrami
Department of Neonatology, Children s National Medical Center and the George Washington University School of Medicine, Washington, DC 20010, USA
Environ Health Perspect 112:1339-40. 2004..Known treatments that involve high DEHP exposures are blood exchange transfusions, extracorporeal membrane oxygenation (ECMO), and cardiovascular surgery...
Mechanical cardiopulmonary support in children and young adults: extracorporeal membrane oxygenation, ventricular assist devices, and long-term support devicesA C Chang
Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, 6621 Fannin, MC 19345-C, Houston, TX 77030, USA
Pediatr Cardiol 26:2-28. 2005
Chest and abdominal CT during extracorporeal membrane oxygenation: Clinical benefits in diagnosis and treatmentMarika K Lidegran
Department of Pediatric Radiology, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Karolinska Institute SE 171 76, Stockholm, Sweden
Acad Radiol 12:276-85. 2005..the clinical usefulness of thoracic and abdominal computed tomography (CT) as an adjunct to bedside diagnostic imaging in patients on extracorporeal membrane oxygenation (ECMO) therapy because of severe acute respiratory failure.
Use of the CDI blood parameter monitoring system 500 for continuous blood gas measurement during extracorporeal membrane oxygenation simulationAaron Schreur
University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
J Extra Corpor Technol 37:377-80. 2005..is used for continuous measurement of venous saturation in a variety of applications, including extracorporeal membrane oxygenation (ECMO), despite clinical reports that have presented data showing poor accuracy of these devices...
Cardiopulmonary bypass/extracorporeal membrane oxygenation/left heart bypass: indications, techniques, and complicationsGorav Ailawadi
Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Virginia, PO Box 800679, Charlottesville, VA 22908 0679, USA
Surg Clin North Am 89:781-96, vii-viii. 2009..Cardiopulmonary bypass, extracorporeal membrane oxygenation, and left heart bypass have revolutionized our ability to operate on the heart, great vessels, and ..
Pharmacokinetics of cefotaxime and desacetylcefotaxime in infants during extracorporeal membrane oxygenationMaurice J Ahsman
Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, Netherlands
Antimicrob Agents Chemother 54:1734-41. 2010b>Extracorporeal membrane oxygenation (ECMO) is used to temporarily sustain cardiac and respiratory function in critically ill infants but can cause pharmacokinetic changes necessitating dose modifications...
Usefulness of extracorporeal membrane oxygenation for early cardiac allograft dysfunctionDave R Listijono
St Vincent s Hospital Clinical School, University of New South Wales, Kensington, New South Wales, Australia
J Heart Lung Transplant 30:783-9. 2011..Because patients who receive a marginal heart may require hemodynamic support in the early post-operative period, extracorporeal membrane oxygenation (ECMO) may be used until recovery of acute graft dysfunction.
Anticoagulation and pediatric extracorporeal membrane oxygenation: impact of activated clotting time and heparin dose on survivalChristopher W Baird
Children s Hospital Boston, Boston, Massachusetts 02115, USA
Ann Thorac Surg 83:912-9; discussion 919-20. 2007Anticoagulation during pediatric extracorporeal membrane oxygenation (ECMO) is accomplished by titrating heparin administration to maintain an activated clotting time (ACT) of between 180 and 220 seconds...
Extracorporeal membrane oxygenation for pediatric respiratory failure: Survival and predictors of mortalityLuke A Zabrocki
Division of Pediatric Critical Care, Department of Pediatrics, Primary Children s Medical Center, University of Utah, Salt Lake City, UT, USA
Crit Care Med 39:364-70. 2011The last multicentered analysis of extracorporeal membrane oxygenation in pediatric acute respiratory failure was completed in 1993. We reviewed recent international data to evaluate survival and predictors of mortality.
Management benefits and safety of computed tomography in patients undergoing extracorporeal membrane oxygenation therapy: experience of a single centreS L Jepson
Department of Radiology, University Hospitals of Leicester, UK
Clin Radiol 65:881-6. 2010To evaluate the benefits and logistical safety of computed tomography (CT) imaging in patients undergoing extracorporeal membrane oxygenation (ECMO) therapy in a single institution.
Extracorporeal membrane oxygenation for severe influenza A (H1N1) acute respiratory distress syndrome: a prospective observational comparative studyAntoine Roch
Service de Reanimation, Hopital Sainte Marguerite, hopitaux Sud, 13274, Marseille Cedex 9, France
Intensive Care Med 36:1899-905. 2010To compare characteristics, clinical evolution and outcome in adult patients with influenza A (H1N1) acute respiratory distress syndrome (ARDS) treated with or without extracorporeal membrane oxygenation (ECMO).
Current status of extracorporeal life support (ECMO) for cardiopulmonary failureR H Bartlett
Department of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA
Minerva Anestesiol 76:534-40. 2010..life support with artificial heart and lung for cardiopulmonary failure is commonly called extracorporeal membrane oxygenation (ECMO)...
Respiratory failure and extracorporeal membrane oxygenationBjorn Frenckner
Department of Pediatric Surgery, Astrid Lindgren Children s Hospital, Karolinska Institutet, Stockholm, Sweden
Semin Pediatr Surg 17:34-41. 2008..If adequate gas exchange still cannot be achieved extracorporeal membrane oxygenation (ECMO) may be an option...
Phaeochromocytoma crisis--a rare indication for extracorporeal membrane oxygenationA Chao
Department of Anaesthesia and Intensive Care, National Taiwan University Hospital, 7, Chung Shan S Road, Taipei, 100, Taiwan
Anaesthesia 63:86-8. 2008..Veno-arterial extracorporeal membrane oxygenation was used for the management of refractory cardiogenic shock and massive lung oedema...
Catastrophic catecholamine-induced cardiomyopathy mimicking acute myocardial infarction, rescued by extracorporeal membrane oxygenation (ECMO) in pheochromocytomaIl Woo Suh
Department of Medicine, Division of Cardiology, Asan Medical Center, University of Ulsan, 388 1 Pungnap dong, Songpa Gu, Seoul, Korea
J Korean Med Sci 23:350-4. 2008..We decided to apply extracorporeal membrane oxygenation (ECMO) device for the patient. His clinical state began to improve 3 days after ECMO...
Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centreAdriano Peris
Anaesthesia and Intensive Care Unit of Emergency Department, Careggi Teaching Hospital, Florence, Italy
Scand J Trauma Resusc Emerg Med 18:28. 2010Extracorporeal Life Support (ECLS) and extracorporeal membrane oxygenation (ECMO) have been indicated as treatment for acute respiratory and/or cardiac failure...
Extracorporeal membrane oxygenation with nafamostat mesilate as an anticoagulant for massive pulmonary hemorrhage after living-donor lobar lung transplantationKazutoshi Kotani
Departments of Oncology and Thoracic Surgery, Emergency Medicine, Cardiovascular Surgery, and Anesthesiology and Resuscitology, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan
J Thorac Cardiovasc Surg 124:626-7. 2002
ECMO-assisted carinal resection and reconstruction after left pneumonectomyJie Lei
Department of Thoracic Surgery, Tang Du Hospital, Fourth Military Medical University, Xi an, Shaanxi 710038, China
J Cardiothorac Surg 5:89. 2010b>Extracorporeal Membrane Oxygenation (ECMO) has become an increasingly important technique for patients with respiratory or cardiac failure for a variety of causes...
First experience with the ultra compact mobile extracorporeal membrane oxygenation system Cardiohelp in interhospital transportAlois Philipp
Department of Cardiothoracic Surgery, University Medical Center, 93053 Regensburg, Germany
Interact Cardiovasc Thorac Surg 12:978-81. 2011..Accordingly, the Cardiohelp system was implanted as a venovenous extracorporeal membrane oxygenation (ECMO) in five patients and as a venoarterial system in one patient...
Maintaining adequate anticoagulation on extracorporeal membrane oxygenation therapy: Hemochron Junior Low Range versus Hemochron 400Christopher E Colby
Division of Neonatal and Developmental Medicine, Stanford University, Palo Alto, California 94304, USA
J Extra Corpor Technol 35:35-8. 2003b>Extracorporeal membrane oxygenation (ECMO) therapy requires that patients be anticoagulated to prevent clotting and thrombotic complications...
Use of venovenous extracorporeal membrane oxygenation and an atrial septostomy for pulmonary and right ventricular failureDaniele Camboni
Extracorporeal Life Support Laboratory, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
Ann Thorac Surg 91:144-9. 2011..This study was designed to evaluate the effectiveness of an atrial septostomy with venovenous extracorporeal membrane oxygenation (VV-ECMO) as a novel potential bridge to transplantation.
Blade and balloon atrial septostomy for left heart decompression in patients with severe ventricular dysfunction on extracorporeal membrane oxygenationP M Seib
Department of Pediatric Cardiology, David M Clark Cardiovascular Center, Arkansas Children s Hospital, University of Arkansas for Medical Sciences, Little Rock 72202, USA
Catheter Cardiovasc Interv 46:179-86. 1999b>Extracorporeal membrane oxygenation (ECMO) is used as circulatory support or bridge to transplantation in patients with severe left ventricular (LV) dysfunction...
The split abdominal wall muscle flap repair for large congenital diaphragmatic hernias on extracorporeal membrane oxygenationPeter B Brant Zawadzki
Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA
J Pediatr Surg 42:1047-50; discussion 1051. 2007..not gained widespread use, and some have suggested that it would be inappropriate in the setting of extracorporeal membrane oxygenation (ECMO) because of bleeding risk...
Coagulation and anticoagulation in extracorporeal membrane oxygenationW Muntean
Department of Pediatrics, University of Graz, Austria
Artif Organs 23:979-83. 1999The hemostatic system poses a major problem in extracorporeal membrane oxygenation (ECMO). The foreign surface in the extracorporeal circuit activates platelets and the clotting system...
Extracorporeal membrane oxygenation in primary graft failure after heart transplantationSilvana F Marasco
Cardiothoracic Surgery Unit, The Alfred Hospital, Melbourne, Australia
Ann Thorac Surg 90:1541-6. 2010The aim of this review was to analyze our results with extracorporeal membrane oxygenation (ECMO) support for primary graft failure (PGF) in heart transplant recipients.
Patients supported by extracorporeal membrane oxygenation and acute dialysis: acute physiology and chronic health evaluation score in predicting hospital mortalityVin Cent Wu
Division of Nephrology, National Taiwan University Hospital, Taipei, Taiwan
Artif Organs 34:828-35. 2010b>Extracorporeal membrane oxygenation (ECMO) can provide short-term cardiopulmonary support to critically ill patients. Among ECMO patients, acute renal failure requiring dialysis has an ominous prognosis...
Low-dose nitric oxide therapy for persistent pulmonary hypertension of the newborn. Clinical Inhaled Nitric Oxide Research GroupR H Clark
Department of Pediatrics, Duke University, Durham, NC, USA
N Engl J Med 342:469-74. 2000Inhaled nitric oxide improves gas exchange in neonates, but the efficacy of low-dose inhaled nitric oxide in reducing the need for extracorporeal membrane oxygenation has not been established.
Extracorporeal membrane oxygenation (ECMO) reconsideredJohn L Moran
Department of Intensive Care Medicine, The Queen Elizabeth Hospital, Adelaide, SA, Australia
Crit Care Resusc 12:131-5. 2010The role of extracorporeal membrane oxygenation (ECMO) in the treatment of the acute respiratory distress syndrome (ARDS) is controversial, notwithstanding the recent publication of the results of the CESAR (Conventional Ventilation or ..
Recombinant factor VII for severe bleeding during extracorporeal membrane oxygenation following open heart surgeryBirgit Wittenstein
Great Ormond Street Hospital for Children, London, UK
Pediatr Crit Care Med 6:473-6. 2005..Severe bleeding is a recognized complication during mechanical cardiopulmonary support with extracorporeal membrane oxygenation. We present the use of recombinant activated factor VII (rFVIIa) for severe, refractory bleeding ..
Institutional experience with extracorporeal membrane oxygenation in lung transplantationClemens Aigner
Department of Cardio Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
Eur J Cardiothorac Surg 31:468-73; discussion 473-4. 2007b>Extracorporeal membrane oxygenation (ECMO) is currently accepted in lung transplantation either to bridge patients to transplantation or to treat postoperatively arising severe primary graft failure...
Extracorporeal membrane oxygenation after cardiac arrest in children: what do we know?Myrthe Tajik
School of Medicine and Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands
Eur J Cardiothorac Surg 33:409-17. 2008The use of extracorporeal membrane oxygenation (ECMO) as a resuscitative measure during or after manual cardiopulmonary resuscitation (CPR) shows sharply contrasting results...
Pilot investigation of hypothermia in neonates receiving extracorporeal membrane oxygenationS Ichiba
Heart Link ECMO Centre, Department of Cardiothoracic Surgery, Glenfield Hospital, Leicester, UK
Arch Dis Child Fetal Neonatal Ed 88:F128-33. 2003BACKGROUND: Infants requiring extracorporeal membrane oxygenation (ECMO) support represent a high risk group in terms of cerebral injury...
Venovenous extracorporeal membrane oxygenation in neonatal respiratory failure: does routine, cephalad jugular drainage improve outcome?Erik D Skarsgard
Department of Surgery, British Columbia Children s Hospital, the Centre for Health Innovation and Improvement, and the University of British Columbia, Vancouver, British Columbia, Canada
J Pediatr Surg 39:672-6. 2004b>Extracorporeal membrane oxygenation (ECMO), may be life saving for infants with severe respiratory failure, and when possible, veno-venous bypass through a jugular double lumen cannula, can be expected to provide satisfactory support for ..
Surfactant application during extracorporeal membrane oxygenation improves lung volume and pulmonary mechanics in children with respiratory failureMichael Hermon
Division of Neonatology and Pediatric Intensive Care, University Children s Hospital, Medical University of Vienna, Austria
Crit Care 9:R718-24. 2005This study was performed to determine whether surfactant application during extracorporeal membrane oxygenation (ECMO) improves lung volume, pulmonary mechanics, and chest radiographic findings in children with respiratory failure or ..
Outcome in neonates with congenital heart disease referred for respiratory extracorporeal membrane oxygenationKate L Brown
Cardiac Intensive Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
Acta Paediatr 94:1280-4. 2005To evaluate the proportion of neonates referred for extracorporeal membrane oxygenation (ECMO) support in the modern era of advanced conventional treatments for respiratory failure who actually had congenital heart disease (CHD), and to ..
Extracorporeal life supportSean C Skinner
Section of Pediatric Surgery, University of Michigan, Ann Arbor, Michigan 48109 0245, USA
Semin Pediatr Surg 15:242-50. 2006..Such advances in technology will allow broader and more routine application of ECLS for lung and other organ system failure...
Extracorporeal membrane oxygenation in infants with congenital diaphragmatic hernia: a systematic review of the evidenceF Morini
Department of Paediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
Eur J Pediatr Surg 16:385-91. 2006AIM: The aim of this study was to evaluate the evidence supporting the use of extracorporeal membrane oxygenation (ECMO) in infants with congenital diaphragmatic hernia (CDH) and severe respiratory failure...
Evaluation of oxygenators and centrifugal pumps for long-term pediatric extracorporeal membrane oxygenationA P S Thiara
Department of Thoracic and Cardiovascular Surgery, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
Perfusion 22:323-6. 2007Two extracorporeal membrane oxygenation (ECMO) circuits for children under 10 kg were evaluated and compared for plasma leakage, hemolysis, blood transfusions, and durability.
Clinical outcomes and experience of 20 pediatric patients treated with extracorporeal membrane oxygenation in Fuwai HospitalJu Zhao
Department of Cardiopulmonary Bypass, Fuwai Cardiovascular Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, People s Republic of China
ASAIO J 54:302-5. 2008..study was to report retrospectively the summarized clinical findings from 20 consecutive pediatric extracorporeal membrane oxygenation (ECMO) patients and to investigate the factors associated with mortality...
Clinical correlations and pulmonary function at 8 years of age after severe neonatal respiratory failureCarina M Majaesic
Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
Pediatr Pulmonol 42:829-37. 2007..The aim of this study was to determine the pulmonary sequelae of severe neonatal respiratory failure...
Postdischarge follow-up of infants with congenital diaphragmatic herniaKevin P Lally
Pediatrics 121:627-32. 2008..Structured follow-up for these patients facilitates early recognition and treatment of these complications. In this report, follow-up of infants with congenital diaphragmatic hernia is outlined...
Early experience with low-prime (99 ml) extracorporeal membrane oxygenation support in childrenYasumori Yamasaki
Department of Clinical Engineering, National Cardiovascular Center, Osaka, Japan
ASAIO J 52:110-4. 2006Quick setup is mandatory for cardiopulmonary resuscitation using an extracorporeal membrane oxygenation (ECMO) assist device...
A 5-year survey of nitric oxide use in a pediatric intensive care unitAngela Ryan
University of Missouri School of Medicine, Columbia, MO 65212, USA
Am J Ther 14:253-8. 2007..014). No significant adverse effects requiring therapy other than decreasing the inhaled NO concentration were noted. Potential interventions and practices to limit the unwarranted use of this costly agent are discussed...
Extracorporeal life support after staged palliation of a functional single ventricle: subsequent morbidity and survivalAparna Hoskote
Department of Critical Care Medicine, The Hospital for Sick Children and University of Toronto, Toronto, Canada
J Thorac Cardiovasc Surg 131:1114-21. 2006..b>Extracorporeal membrane oxygenation was initiated in 19 patients, with conversion to a ventricular assist device in 7 patients...
Neonatal extracorporeal life support: impact of new therapies on survivalPaola J Fliman
Division of Neonatology, Northwestern University, Chicago, Illinois, USA
J Pediatr 148:595-9. 2006..To evaluate the effects of pre-extracorporeal life support (ECLS) management with nitric oxide (NO), high frequency ventilation (HFV), and surfactant on mortality among neonates supported with ECLS...
Experience with extracorporeal life support in pediatric patients after cardiac surgeryShu-Chien Huang
Department of Surgery, National Taiwan University Hospital, 7 Chung-Shan S. Rd, Taipei 100, Taiwan
ASAIO J 51:517-21. 2005..In conclusion, nonbiventricular physiology, acute renal failure, and high blood lactate levels after ECLS increased the risk of mortality for pediatric patients requiring ECLS for postoperative cardiac support...
A 22-year experience in global transport extracorporeal membrane oxygenationChristopher P Coppola
Department of Surgery, Wilford Hall Medical Center, San Antonio, Lackland AFB, TX 78236, USA
J Pediatr Surg 43:46-52; discussion 52. 2008Transport extracorporeal membrane oxygenation (ECMO) is currently available at 12 centers. We report a 22-year experience from the only facility providing global transport ECMO...
Postoperative extracorporeal life support in pediatric cardiac surgery: recent resultsOlivier Ghez
Department of Thoracic and Cardiovascular Surgery, Children s Hospital La Timone, Bd J Moulin, 13005 Marseille, France
ASAIO J 51:513-6. 2005..These results support early placement of ECLS in children whenever a severe postoperative hemodynamic or respiratory failure, refractory to medical treatment, is present...
Redefining outcomes in right congenital diaphragmatic herniaJason C Fisher
Division of Pediatric Surgery, Columbia University College of Physicians and Surgeons New York, NY 10032, USA
J Pediatr Surg 43:373-9. 2008..To define the behavior and outcomes of R-CDH better, we report the largest single-institution series of R-CDH and ask if factors traditionally linked to poor prognosis in L-CDH were applicable to R-CDH...
Intraoperative extracorporeal membrane oxygenation and survival of pediatric patients undergoing repair of congenital heart diseaseRandall P Flick
Department of Anesthesiology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Paediatr Anaesth 18:757-66. 2008We studied the association between the introduction of extracorporeal membrane oxygenation (ECMO) into routine practice and the survival of children who failed weaning from cardiopulmonary bypass (CPB)...
Extracorporeal membrane oxygenation in children after repair of congenital cardiac lesionsA S Aharon
Department of Cardiac and Thoracic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232-5734, USA
Ann Thorac Surg 72:2095-101; discussion 2101-2. 2001BACKGROUND: The purpose of this study was to review our experience in the early application of extracorporeal membrane oxygenation (ECMO) in patients requiring mechanical assistance after cardiac surgical procedures...
Right congenital diaphragmatic hernia: Prenatal assessment and outcomeHolly L Hedrick
Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA
J Pediatr Surg 39:319-23; discussion 319-23. 2004..Twelve of 23 (52%) required extracorporeal membrane oxygenation (ECMO) with a 75% survival rate...
The impact of changing neonatal respiratory management on extracorporeal membrane oxygenation utilizationT T Hui
Los Angeles, California, USA
J Pediatr Surg 37:703-5. 2002..INO) and high-frequency oscillatory ventilation (HFV) has had a profound effect on the use of extracorporeal membrane oxygenation (ECMO) for respiratory failure in neonates without congenital diaphragmatic hernia (CDH)...
Fatal pulmonary hypertension associated with pertussis in infants: does extracorporeal membrane oxygenation have a role?Natasha B Halasa
Division of Pediatric Infectious Disease, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2573, USA
Pediatrics 112:1274-8. 2003..of 4 infants who had confirmed pertussis infection at our hospital during the past year motivated us to review their cases as well as the use of extracorporeal membrane oxygenation (ECMO) in respiratory failure caused by pertussis.
Impact of AMICAR on hemorrhagic complications of ECMO: a ten-year reviewCynthia D Downard
Department of Surgery and Respiratory Therapy, Children's Hospital, Boston-Harvard Medical School, Boston, MA 02445, USA
J Pediatr Surg 38:1212-6. 2003..the incidence of intracranial hemorrhage and significant surgical site bleeding in patients on extracorporeal membrane oxygenation (ECMO)...
Venovenous versus venoarterial extracorporeal membrane oxygenation in congenital diaphragmatic herniaAmir Kugelman
Department of Neonatology, Bnai-Zion Medical Center, Technion-Faculty of Medicine, Haifa, Israel
J Pediatr Surg 38:1131-6. 2003BACKGROUND: Extracorporeal membrane oxygenation (ECMO) has a significant role as a final rescue modality in severe respiratory failure of the newborn with congenital diaphragmatic hernia (CDH)...
Neurodevelopmental outcome of infants supported with extracorporeal membrane oxygenation after cardiac surgeryShannon E G Hamrick
Department of Pediatrics, University of California San Francisco, 521 Parnassus Ave, C 215, San Francisco, CA 94122 0663, USA
Pediatrics 111:e671-5. 2003To evaluate the long-term neurodevelopmental outcome of infants who underwent cardiac surgery and required extracorporeal membrane oxygenation (ECMO) support, and to examine variables that predict death or disability in these patients.
The clinical significance of the reoxygenation injury in pediatric heart surgeryBradley S Allen
Division of Cardiovascular Surgery, The Heart Institute for Children, Hope Children s Hospital, Oak Lawn, IL 60453, USA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 6:116-27. 2003..this injury can be modified and possibly ameliorated by changes in the intraoperative management of cardiopulmonary bypass...
Surfactant phosphatidylcholine pool size in human neonates with congenital diaphragmatic hernia requiring ECMODaphne J M T Janssen
Department of Pediatrics/Neonatology, Sophia Children's Hospital/Erasmus University Rotterdam, The Netherlands
J Pediatr 142:247-52. 2003..PC) pool size and half-life in human congenital diaphragmatic hernia (CDH) patients who required extracorporeal membrane oxygenation (ECMO)...
Early perfluorodecalin lung distension in infants with congenital diaphragmatic herniaG M Walker
Department of Surgical Paediatrics, Royal Hospital for Sick Children, Yorkhill NHS Trust, Glasgow, Scotland
J Pediatr Surg 38:17-20; discussion 17-20. 2003..The authors present a study measuring perfluorodecalin distension in neonates with severe CDH on extracorporeal membrane oxygenation (ECMO) support. METHODS: Six consecutive neonates with CDH requiring ECMO support were recruited...
Development of disposable self-regulating blood pumps and automatically-controlled portable extracorporeal membrane oxygenation systems for neonatal extracorporeal membrane oxygenationTakahiko Seo
Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
Artif Organs 27:192-8. 2003..This automatic ECMO system required fewer personnel expenditures and was also favorable in terms of hematological findings...
Mechanical circulatory support for the treatment of children with acute fulminant myocarditisB W Duncan
Division of Cardiac Surgery, Children's Hospital and Regional Medical Center, University of Washington, School of Medicine, Seattle, Wash, USA
J Thorac Cardiovasc Surg 122:440-8. 2001..METHODS: A retrospective chart review of 15 children with viral myocarditis supported with extracorporeal membrane oxygenation (12 patients) or ventricular assist devices (3 patients) was performed...
[Are there some clinical factors that indicate the best moment of the surgery in the congenital diaphragmatic hernia?]A Parente
Servicio Cirugía Pediátrica, Hospital infantil Gregorio Marañón, Madrid
Cir Pediatr 19:232-5. 2006..To determine if the needs of cardiopulmonary support of neonates with congenital diaphragmatic hernia (CDH) they can be indicators for the election of the most suitable moment to the surgery...
Inhaled nitric oxide with early surgery improves the outcome of antenatally diagnosed congenital diaphragmatic herniaHiroomi Okuyama
Department of Pediatric Surgery, Osaka Medical Center for Maternal and Child Health, Izumi, Osaka, Japan
J Pediatr Surg 37:1188-90. 2002..High-frequency oscillatory ventilation (HFOV) was used routinely during the study periods, and extracorporeal membrane oxygenation (ECMO) was used on basis of conventional entry criteria...
A 16-year neonatal/pediatric extracorporeal membrane oxygenation transport experienceBernard J Wilson
Department of Pediatrics, Section of Newborn Medicine, San Antonio Military Pediatric Center, San Antonio, Texas, USA
Pediatrics 109:189-93. 2002..survival of neonatal and pediatric patients transported by Wilford Hall Medical Center (WHMC) on extracorporeal membrane oxygenation (ECMO) since 1985...
Congenital diaphragmatic hernia: experience without extracoporeal membrane oxygenationSaud Al-Shanafey
Department of Surgery, Dalhousie University, IWK-Grace Health Centre, 5850 University Avenue, Halifax, Nova Scotia B3J 3G9, Canada
Pediatr Surg Int 18:28-31. 2002While extracorporeal membrane oxygenation (ECMO) is used in the management of congenital diaphragmatic hernia (CDH), its value is questioned...
Mechanical versus medical bridge to transplantation in children. What is the best timing for mechanical bridge?Shekar L C Reddy
Department of Cardiac Surgery, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
Eur J Cardiothorac Surg 25:605-9. 2004..In this study we compared biochemical and clinical parameters between children who received mechanical circulatory support and those who were treated with medical management alone as a bridge to transplantation...
Primary use of the venovenous approach for extracorporeal membrane oxygenation in pediatric acute respiratory failureRobert Pettignano
Nemours Children's Clinic, Arnold Palmer Hospital for Children and Women, Orlando, FL 32806, USA
Pediatr Crit Care Med 4:291-8. 2003..use of venovenous cannulation for supporting pediatric acute respiratory failure patients with extracorporeal membrane oxygenation (ECMO)...
Experience with mobile inhaled nitric oxide during transport of neonates and children with respiratory insufficiency to an extracorporeal membrane oxygenation centerClaire Westrope
Heartlink ECMO Centre, Glenfield Hospital, Leicester, UK
Pediatr Crit Care Med 5:542-6. 2004..use of inhaled nitric oxide (iNO) during the transport of ventilated neonates and children to an extracorporeal membrane oxygenation (ECMO) center and to discuss the efficacy and safety of iNO use in this situation...
Research Grants
- Safety and Efficacy of the Berlin Heart EXCOR Pediatric VAD as a bridge-to-heart ROBERT M KROSLOWITZ; Fiscal Year: 2010..b>Extracorporeal membrane oxygenation (ECMO), the standard of care for pediatric mechanical support in the U.S...
- Noninvasive Methemoglobin Monitoring TechnologyLEONARD WINCHESTER; Fiscal Year: 2007..The inhaled nitric oxide therapy effectively decreases the need for extracorporeal membrane oxygenation treatment...
- Compliant Thoracic Artificial LungsKeith Cook; Fiscal Year: 2009..full gas transfer requirements with significantly less coagulation and inflammation than with extracorporeal membrane oxygenation (ECMO). Our group's previous work has led to devices that met these goals in large animals...
- Compliant Thoracic Artificial LungsKEITH ELLIOT COOK; Fiscal Year: 2010..full gas transfer requirements with significantly less coagulation and inflammation than with extracorporeal membrane oxygenation (ECMO). Our group's previous work has led to devices that met these goals in large animals...
- Compliant Thoracic Artificial LungsKeith Cook; Fiscal Year: 2009..full gas transfer requirements with significantly less coagulation and inflammation than with extracorporeal membrane oxygenation (ECMO). Our group's previous work has led to devices that met these goals in large animals...
- Metabolism During Mechanical Circulatory Support in the Developing HeartMichael A Portman; Fiscal Year: 2010b>Extracorporeal membrane oxygenation (ECMO) remains the primary method of long term support after myocardial stunning caused by cardiac surgery in infants and children. ECMO often provides a bridge to recovery in these young patients...
- Metabolism During Mechanical Circulatory Support in the Developing HeartMichael A Portman; Fiscal Year: 2010b>Extracorporeal membrane oxygenation (ECMO) remains the primary method of long term support after myocardial stunning caused by cardiac surgery in infants and children. ECMO often provides a bridge to recovery in these young patients...
- Biocompatible Coating for Pediatric Blood OxygenatorsPatrick Cahalan; Fiscal Year: 2006Project Summary/Abstract: Many oxygenators clinically available for adult and pediatric extracorporeal membrane oxygenation (ECMO) employ heparin coatings on microporous hollow fibers to improve biocompatibility...
- Pediatric Cardiac Monitor for Extracorporeal Life SupportNikolai Krivitski; Fiscal Year: 2005..to assess the cardiac function at the end of bypass surgery and prior to weaning the patient from extracorporeal membrane oxygenation (ECMO), to quantitatively evaluate the effectiveness of the therapy...
- Positional mapping of a gene for Alveolar Capillary Dys*Bassem Bejjani; Fiscal Year: 2004..include mechanical ventilation, high concentrations of inspired oxygen, inhaled nitric oxide, and extracorporeal membrane oxygenation (ECMO) support...
- ALTERNATIVES TO ECMO FOR PEDIATRIC CIRCULATORY SUPPORTGeorge Pantalos; Fiscal Year: 2002..A current common practice is to support these patients with extracorporeal membrane oxygenation circuitry (ECMO), even when the indications for support are purely cardiac, due to the clinical ..
- Safety and Efficacy of the Berlin Heart EXCOR Pediatric VAD as a bridge-to-heart ROBERT KROSLOWITZ; Fiscal Year: 2009..b>Extracorporeal membrane oxygenation (ECMO), the standard of care for pediatric mechanical support in the U.S...
- Pediatric ECMO CathetersRichard Martin; Fiscal Year: 2004This proposal is for the development of specialty catheters designed to make single catheter ECMO (Extracorporeal Membrane Oxygenation) available to pediatric patients over 14 kg...
- Integrated Maglev Pump-Oxygenator for Respiratory SupportKurt Dasse; Fiscal Year: 2006..Current treatment is limited to extracorporeal membrane oxygenation (ECMO), but ECMO systems are generally assembled from multiple, unmatched components to create a ..
- ECMO IN PEDIATRIC RESPIRATORY FAILURERobert Bartlett; Fiscal Year: 1992..For the past 16 years this work has been supported by NIH. As a result of these studies extracorporeal membrane oxygenation (ECMO) has been studied in the laboratory, evaluated in adults, and has become standard treatment ..
- ECMO IN RESPIRATORY FAILURERobert Bartlett; Fiscal Year: 1993..As a result of these studies ECLS (also known as extracorporeal membrane oxygenation, ECMO), has been studied in the laboratory, evaluated in patients, and has become standard ..
- Pneumatically actuated integrated life support systemMark Gartner; Fiscal Year: 2002..MedEvac" field as a potential enabling technology to improve safety of transports with patients on extracorporeal membrane oxygenation (ECMO) or cardiopulmonary bypass (CPB)...
- An Artificial Myocardium for Pediatric SupportRobert Stewart; Fiscal Year: 2007..This is in spite of the fact that most cases for cardiac support via extracorporeal membrane oxygenation (ECMO) are for infants following complex surgical reconstructions for congenital defects...
