Genomes and Genes
Summary: The genetic process of crossbreeding between genetically dissimilar parents to produce a hybrid.
Publications271 found, 100 shown here
- Hybrid speciationJames Mallet
Galton Laboratory, Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK
Nature 446:279-83. 2007..Now, new genetic evidence suggests that hybrid speciation, even without polyploidy, is more common in plants and also animals than we thought...
- The role of hybridization in evolutionN H Barton
Institute of Cell, Animal and Population Biology, University of Edinburgh, King s Buildings, Edinburgh EH9 3JT, UK
Mol Ecol 10:551-68. 2001..Moreover, because adaptation is via substitutions of small effect, Fisher's model does not generate the strong effects of single chromosome regions often observed in species crosses...
- A model-based method for identifying species hybrids using multilocus genetic dataE C Anderson
Department of Statistics, University of Washington, Seattle, Washington 98195, USA
Genetics 160:1217-29. 2002..We demonstrate the method on allozyme data from two species of hybridizing trout, as well as on two simulated data sets...
- Transgressive segregation, adaptation and speciationL H Rieseberg
Department of Biology, Indiana University, Bloomington, IN 47405, USA
Heredity (Edinb) 83:363-72. 1999..These results lend credence to the view that hybridization may provide the raw material for rapid adaptation and provide a simple explanation for niche divergence and phenotypic novelty often associated with hybrid lineages...
- Genomewide nonadditive gene regulation in Arabidopsis allotetraploidsJianlin Wang
Department of Agronomy, University of Wisconsin, Madison, Wisconsin 53706, USA
Genetics 172:507-17. 2006....
- Hybrid zones and the genetic architecture of a barrier to gene flow between two sunflower speciesL H Rieseberg
Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
Genetics 152:713-27. 1999..These results demonstrate the utility of hybrid zones for identifying factors contributing to isolation and verify the prediction of increased resolution relative to controlled crosses...
- Efficiency of model-based Bayesian methods for detecting hybrid individuals under different hybridization scenarios and with different numbers of lociJuha Pekka Vähä
Department of Biological and Environmental Sciences, PO Box 65, FIN 00014, University of Helsinki, Finland
Mol Ecol 15:63-72. 2006..However, separating backcrosses from purebred parental individuals requires a considerable genotyping effort (at least 48 loci), even when divergence between parental populations is high...
- Allelic variation and heterosis in maize: how do two halves make more than a whole?Nathan M Springer
Cargill Center for Microbial and Plant Genomics, Department of Plant Biology, University of Minnesota, Saint Paul, Minnesota 55108, USA
Genome Res 17:264-75. 2007..Variation for the presence of genes, the presence of novel beneficial alleles, and modified levels of gene expression in hybrids may all contribute to the heterotic phenotypes...
- Major ecological transitions in wild sunflowers facilitated by hybridizationLoren H Rieseberg
Department of Biology, Indiana University, Bloomington, IN 47405, USA
Science 301:1211-6. 2003..The same combinations of parental chromosomal segments required to generate extreme phenotypes in synthetic hybrids also occurred in ancient hybrids. Thus, hybridization facilitated ecological divergence in sunflowers...
- Emerging vectors in the Culex pipiens complexDina M Fonseca
Genetics Program, Smithsonian Institution, National Museum of Natural History, 3001 Connecticut Avenue N W, Washington, DC 20008 0551, USA
Science 303:1535-8. 2004..Such hybrids between human-biters and bird-biters may be the bridge vectors contributing to the unprecedented severity and range of the West Nile virus epidemic in North America...
- Genomic plasticity and the diversity of polyploid plantsA R Leitch
School of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK
Science 320:481-3. 2008..This process has been a major driving force behind the divergence of the angiosperms and their biodiversity...
- Adaptive evolution drives divergence of a hybrid inviability gene between two species of DrosophilaDaven C Presgraves
Department of Biology, University of Rochester, Rochester, New York 14627, USA
Nature 423:715-9. 2003..These results show that a lethal hybrid incompatibility has evolved as a by-product of adaptive protein evolution...
- Speciation via introgressive hybridization in East African cichlids?W Salzburger
Department of Zoology and Limnology, University of Innsbruck, Technikerstrasse 25, A 6020 Innsbruck, Austria
Mol Ecol 11:619-25. 2002..Hence, our finding displays another mode of speciation in cichlid fishes. The increase of genetic and phenotypic diversity due to hybridization may contribute to the uniquely rapid pace of speciation in cichlids...
- A yeast hybrid provides insight into the evolution of gene expression regulationItay Tirosh
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
Science 324:659-62. 2009..These results provide insights on the regulatory changes in cis and trans during the divergence of species and upon hybridization...
- Differential patterns of introgression across the X chromosome in a hybrid zone between two species of house miceBret A Payseur
Department of Ecology and Evolutionary Biology, Biosciences West Building, University of Arizona, Tucson, Arizona 85721, USA
Evolution 58:2064-78. 2004..This study highlights the utility of natural populations of hybrids for mapping speciation genes and suggests that the middle of the X chromosome may be important for reproductive isolation between species of house mice...
- A genomic view of introgression and hybrid speciationEric J Baack
Department of Botany, University of British Columbia, Vancouver, BC, Canada
Curr Opin Genet Dev 17:513-8. 2007....
- Dominance, epistasis and the genetics of postzygotic isolationM Turelli
Section of Evolution and Ecology and Center for Population Biology, University of California, Davis 95616, USA
Genetics 154:1663-79. 2000..Such incompatibilities are common in Drosophila species crosses, and their consequences in male- vs. female-heterogametic taxa may explain the pattern of exceptions to Haldane's rule...
- The hidden side of invasions: massive introgression by local genesMathias Currat
Computational and Molecular Population Genetics Laboratory, Institute of Zoology, University of Bern, Baltzerstrasse 6, 3012 Berne, Switzerland
Evolution 62:1908-20. 2008..Our results imply that speciation genes can be identified by comparing genomes of interfertile native and invading species pairs...
- Evolution and expression of homeologous loci in Tragopogon miscellus (Asteraceae), a recent and reciprocally formed allopolyploidJennifer A Tate
Department of Botany, University of Florida, Gainesville, Florida 32611, USA
Genetics 173:1599-611. 2006..Synthetic F(1) hybrids between putative diploid progenitors are additive of their parental genomes, suggesting that polyploidization rather than hybridization induces genomic changes in Tragopogon...
- Sequence elimination and cytosine methylation are rapid and reproducible responses of the genome to wide hybridization and allopolyploidy in wheatH Shaked
Department of Plant Sciences, The Weizmann Institute of Science, Rehovot 76100, Israel
Plant Cell 13:1749-59. 2001....
- Speciation in reverse: morphological and genetic evidence of the collapse of a three-spined stickleback (Gasterosteus aculeatus) species pairE B Taylor
Department of Zoology and Biodiversity Research Centre, University of British Columbia, 6270 University Blvd, Vancouver, BC V6T 1Z4, Canada
Mol Ecol 15:343-55. 2006..Although the precise mechanism(s) responsible for elevated hybridization in the lake is unknown, the demise of the Enos Lake species pair follows the appearance of an exotic crayfish, Pascifasticus lenisculus, in the early 1990s...
- Comparative expression profiling in meristems of inbred-hybrid triplets of maize based on morphological investigations of heterosis for plant heightAnna Uzarowska
Department of Plant Breeding, Technical University of Munich, Freising, Germany
Plant Mol Biol 63:21-34. 2007..Quantitative RT-PCR was applied in order to validate microarray results. The role of the differentially expressed genes in relation to heterosis for PHT is discussed...
- Hybridization and adaptive mate choice in flycatchersT Veen
Department of Animal Ecology, Evolutionary Biology Centre, Uppsala University, SE-752 36 Uppsala, Sweden
Nature 411:45-50. 2001..Apparent hybridization may thus represent adaptive mate choice under some circumstances...
- Evidence of hybridity in invasive watermilfoil (Myriophyllum) populationsMichael L Moody
Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs 06269 3043, USA
Proc Natl Acad Sci U S A 99:14867-71. 2002..These observations suggest that invasiveness in these aggressive aquatic weeds may be linked to heterosis maintained by vegetative propagation...
- Genetic analysis of variation in gene expression in Arabidopsis thalianaMarnik Vuylsteke
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology VIB, Ghent University, B 9052 Gent, Belgium
Genetics 171:1267-75. 2005..Further advances in the genetic analysis of gene expression variation may contribute to a better understanding of its role in affecting quantitative trait variation at the phenotypic level...
- Dynamics of polyploid formation in Tragopogon (Asteraceae): recurrent formation, gene flow, and population structureV Vaughan Symonds
Florida Museum of Natural History, University of Florida, Gainesville, Florida 32611, USA
Evolution 64:1984-2003. 2010..Our data also indicate a lack of gene flow among polyploid plants of independent origin, even when they co-occur, suggesting potential reproductive barriers among separate lineages in both polyploid species...
- Contrasting patterns of mitochondrial DNA and microsatellite introgressive hybridization between lineages of lake whitefish (Coregonus clupeaformis); relevance for speciationG Lu
GIROQ, , , Ste-Foy, , Canada G1K 7P4
Mol Ecol 10:965-85. 2001..Thus, each lake may be viewed as a different temporal snapshot taken throughout the gradual process of speciation...
- Asymmetry and polymorphism of hybrid male sterility during the early stages of speciation in house miceJeffrey M Good
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
Evolution 62:50-65. 2008..These data build on previous studies of speciation in house mice and show that the genetic basis of hybrid male sterility is fairly complex, even at this early stage of divergence...
- Transcriptome shock after interspecific hybridization in senecio is ameliorated by genome duplicationMatthew J Hegarty
School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, United Kingdom
Curr Biol 16:1652-9. 2006..cambrensis and this altered expression pattern is maintained in subsequent generations. These findings indicate that hybridization and polyploidization have immediate yet distinct effects on large-scale patterns of gene expression...
- Mobilization of the active MITE transposons mPing and Pong in rice by introgression from wild rice (Zizania latifolia Griseb.)Xiaohui Shan
Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun, China
Mol Biol Evol 22:976-90. 2005..In addition, we report an atypical behavior of mPing/Pong mobilization in these lines, i.e., the exclusive absence of footprints after excision...
- Identification of differentially expressed genes in leaf and root between wheat hybrid and its parental inbreds using PCR-based cDNA subtractionYingyin Yao
Department of Plant Genetics and Breeding, Key Laboratory of Crop Genomics and Genetic Improvement, Ministry of Agriculture Beijing, China Agricultural University, 100094 Beijing, China
Plant Mol Biol 58:367-84. 2005..2%). And it was concluded that the genes differentially expressed between hybrids and their parents involved in diverse physiological process pathway, which might be responsible for the observed heterosis...
- Genetic rescue of inviable hybrids between Drosophila melanogaster and its sibling speciesP Hutter
Nature 327:331-3. 1987..melanogaster females and males of its three closest relatives. The study of this locus may shed light on the genetic control of both speciation and development...
- Natural selection for salt tolerance quantitative trait loci (QTLs) in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid speciesC Lexer
Department of Biology, Jordan Hall 142, 1001 East Third Street, Indiana University, Bloomington, IN 47405, USA
Mol Ecol 12:1225-35. 2003..paradoxus. Finally, selection coefficients of +0.126, -0.084 and -0.094 for the three survivorship QTLs, respectively, are sufficiently large to account for establishment of new, homoploid hybrid species...
- The likelihood of homoploid hybrid speciationC A Buerkle
Department of Biology, Indiana University, Bloomington, IN 47405, USA
Heredity (Edinb) 84:441-51. 2000..Our results confirmed the importance of the combination of factors that had been emphasized in verbal models and illustrate the trade-off between the frequency at which hybrid species arise and the genetic integrity of incipient species...
- Complete mitochondrial DNA replacement in a Lake Tanganyika cichlid fishB Nevado
Department Vertebrates, Royal Belgian Institute of Natural Sciences, 1000 Brussels, Belgium
Mol Ecol 18:4240-55. 2009..callipterus mtDNA lineages, probably still during the water level low stand, and that subsequently the invading mtDNA lineage spread throughout the lake...
- Natural hybridization and the evolution of domesticated, pest and disease organismsMichael L Arnold
Department of Genetics, University of Georgia, Athens, GA 30602, USA
Mol Ecol 13:997-1007. 2004..I focus on the effects from genetic exchange that may lead to the acquisition of novel phenotypes and thus increase the beneficial or detrimental (to human populations) aspects of the various taxa...
- Speciation reversal and biodiversity dynamics with hybridization in changing environmentsOle Seehausen
Center of Ecology, Evolution and Biogeochemistry, Swiss Institute for Environmental Sciences and Technology EAWAG, Seestrasse 79, 6047 Kastanienbaum, Switzerland
Mol Ecol 17:30-44. 2008..Since heterogeneity of natural environments is rapidly deteriorating in most biomes, the evolutionary ecology of speciation reversal ought to be fully integrated into conservation biology...
- Weed evolution after crop gene introgression: greater survival and fecundity of hybrids in a new environmentLesley G Campbell
Ecol Lett 9:1198-209. 2006..270% greater lifetime fecundity and c. 22% greater survival than wild plants in CA. Our results support the hypothesis that crop-wild hybridization may create genotypes with the potential to displace parental taxa in new environments...
- Facultative mate choice drives adaptive hybridizationKarin S Pfennig
Department of Biology, Campus Box 3280, Coker Hall, University of North Carolina, Chapel Hill, NC 27599, USA
Science 318:965-7. 2007..Thus, when the benefits of mate choice vary, females may radically alter their mate selection in response to their own phenotype and their environment, even to the point of choosing males of other species...
- Hybridization in the recent pastPeter R Grant
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544 1003, USA
Am Nat 166:56-67. 2005....
- Quantitative trait analysis of seed yield and other complex traits in hybrid spring rapeseed (Brassica napus L.): 2. Identification of alleles from unadapted germplasmJoshua A Udall
Plant Breeding and Plant Genetics Program, and Department of Agronomy, University of Wisconsin, Madison, WI 53706, USA
Theor Appl Genet 113:597-609. 2006..In this QTL region, a chromosome rearrangement was identified in P1804, which may have affected seed yield...
- Genetic dissection of an elite rice hybrid revealed that heterozygotes are not always advantageous for performanceJ P Hua
National Key Laboratory of Crop Genetic Improvement, National Center of Crop Molecular Breeding, Huazhong Agricultural University, Wuhan 430070, China
Genetics 162:1885-95. 2002..It was concluded that heterozygotes were not necessarily advantageous for trait performance even among genotypes derived from such a highly heterotic hybrid...
- Ancient hybridization and mitochondrial capture between two species of chipmunksJeffrey M Good
Department of Ecology and Evolutionary Biology, University of Arizona, Biosciences West, Tucson, AZ 85721, USA
Mol Ecol 17:1313-27. 2008..Our findings challenge long-standing assumptions on patterns of reproductive isolation in chipmunks and suggest that there may be other examples of hybridization among the 23 species of Tamias that occur in western North America...
- Bayesian analyses of admixture in wild and domestic cats (Felis silvestris) using linked microsatellite lociR Lecis
Istituto Nazionale per la Fauna Fauna Selvatica, via Ca Fornacetta 9, 40064 Ozzano dell Emilia Bologna, Italy
Mol Ecol 15:119-31. 2006..Inferred recombination events led to identify the population of origin of chromosomal segments, suggesting that admixture mapping experiments can be designed also in wild populations...
- Serial analysis of gene expression study of a hybrid rice strain (LYP9) and its parental cultivarsJingyue Bao
Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300, China
Plant Physiol 138:1216-31. 2005..Our study adds a new set of data crucial for the understanding of molecular mechanisms of heterosis and gene regulation networks of the cultivated rice...
- Hybrid speciation in experimental populations of yeastDuncan Greig
The Galton Laboratory, Department of Biology, University College London, Gower Street, London WC1E 6BT, UK
Science 298:1773-5. 2002..Extensive karyotypic changes (tetrasomy) were observed in the hybrids, although genic incompatibilities accounted for 50% of the variation in self-fertility...
- Inheritance patterns of transcript levels in F1 hybrid miceXiangqin Cui
Department of Biostatistics, Section on Statistical Genetics, Department of Medicine, Genetic and Translational Medicine Division, University of Alabama, Alabama 35294, USA
Genetics 174:627-37. 2006..In addition, we identified 314 transcripts with expression levels that differ between the reciprocal F1 animals. These genes may be related to maternal effect...
- Variable patterns of introgression in two sculpin hybrid zones suggest that genomic isolation differs among populationsA W Nolte
Max Planck Institute for Evolutionary Biology, August Thienemann Strasse 2, 24306 Plön, Germany
Mol Ecol 18:2615-27. 2009..In the future, data from mapped genetic markers and on variation of ecological factors will provide additional insights into the contribution of these factors to variation in the evolutionary consequences of hybridization...
- The ecological genetics of homoploid hybrid speciationB L Gross
Department of Biology, 1001 E 3rd Street, Jordan Hall 142, Indiana University, Bloomington, IN 47405, USA
J Hered 96:241-52. 2005..Overall, theory and empirical evidence gathered to date suggest that ecological selection is a major factor promoting homoploid hybrid speciation, with the strongest evidence coming from genetic studies...
- Bayesian inference of species hybrids using multilocus dominant genetic markersEric C Anderson
Fisheries Ecology Division, Southwest Fisheries Science Center, Santa Cruz, CA 95060, USA
Philos Trans R Soc Lond B Biol Sci 363:2841-50. 2008..Discriminating between pure-bred and non-pure (hybrid) individuals, however, is shown to be much easier, requiring perhaps as few as 10 dominant markers, even from relatively weakly diverged species...
- Adaptation and selection in the Senecio (Asteraceae) hybrid zone on Mount Etna, SicilyAdrian C Brennan
Sir Harold Mitchell Building, School of Biology, University of St Andrews, St Andrews, Fife, UK
New Phytol 183:702-17. 2009..These results support the hypothesis that extrinsic and intrinsic selection against hybrids maintains the hybrid zone and species distinctiveness despite gene flow between the two Senecio species on Mount Etna...
- Stress and domestication traits increase the relative fitness of crop-wild hybrids in sunflowerKristin L Mercer
Applied Plant Sciences Program, University of Minnesota, 411 Borlaug Hall, 1991 Upper Buford Circle, St Paul, MN 55108, USA
Ecol Lett 10:383-93. 2007..Rigorous assessment of how particular genotypes, phenotypes, and environments affect introgression will improve risk assessment for transgenic crops...
- Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locusDaniel A Barbash
Section of Evolution and Ecology, University of California, Davis, USA
PLoS Biol 2:e142. 2004..Our findings suggest that multiple substitutions driven by natural selection may be a general phenomenon required to generate hybrid incompatibility alleles...
- A rapidly evolving homeobox at the site of a hybrid sterility geneC T Ting
Department of Ecology and Evolution, The University of Chicago, Chicago, IL 60637, USA
Science 282:1501-4. 1998..Such rapid sequence divergence is driven by positive selection and may contribute to reproductive isolation...
- Rates of evolution of hybrid inviability in birds and mammalsBenjamin M Fitzpatrick
Center for Population Biology and Section of Evolution and Ecology, University of California, Davis, California 95616, USA
Evolution 58:1865-70. 2004..I briefly discuss this and other potential explanations...
- Regulatory divergence in Drosophila melanogaster and D. simulans, a genomewide analysis of allele-specific expressionRita M Graze
Genetics Institute, Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida 3261 3610, USA
Genetics 183:547-61, 1SI-21SI. 2009..In addition, two genes, with critical roles in sex determination and micro RNA processing, Sxl and loqs, were identified as misexpressed in hybrid female heads, potentially contributing to hybrid incompatibility...
- Complex hybridization dynamics between golden-winged and blue-winged warblers (Vermivora chrysoptera and Vermivora pinus) revealed by AFLP, microsatellite, intron and mtDNA markersR Vallender
Fuller Evolutionary Biology Program, Laboratory of Ornithology, Cornell University, 159 Sapsucker Woods Road, Ithaca, NY 14850, USA
Mol Ecol 16:2017-29. 2007....
- Rapid radiation, ancient incomplete lineage sorting and ancient hybridization in the endemic Lake Tanganyika cichlid tribe TropheiniStephan Koblmüller
Department of Zoology, Karl Franzens University Graz, Universitatsplatz 2, A 8010 Graz, Austria
Mol Phylogenet Evol 55:318-34. 2010..A large degree of correspondence between AFLP clustering and trophic types indicated fewer cases of parallel evolution of trophic ecomorphology than previously inferred from mitochondrial data...
- Epigenetic, transposon and small RNA determinants of hybrid dysfunctionsP Michalak
Department of Biology, The University of Texas Arlington, Arlington, TX 76019 0498, USA
Heredity (Edinb) 102:45-50. 2009..The review offers a handful of glimpses into these complex dynamics...
- Leaky prezygotic isolation and porous genomes: rapid introgression of maternally inherited DNAKai M A Chan
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544 1003, USA
Evolution 59:720-9. 2005..These findings suggest that we should use extreme caution when interpreting single gene genealogies as species phylogenies, especially for cpDNA and mtDNA...
- Natural selection influences AFLP intraspecific genetic variability and introgression patterns in Atlantic eelsP A Gagnaire
Institut des Sciences de l Evolution ISEM UMR 5554 CNRS UMII, Universite de Montpellier II, Place E Bataillon, Montpellier Cedex 5, France
Mol Ecol 18:1678-91. 2009....
- Conspecific sperm precedence in sister species of Drosophila with overlapping rangesAudrey S Chang
Department of Ecology and Evolution, The University of Chicago, 1101 E 57 Street, Chicago, Illinois 60637, USA
Evolution 58:781-9. 2004..These results suggest that noncompetitive and competitive gametic isolating barriers may contribute to reproductive isolation between D. yakuba and D. santomea...
- The Drosophila melanogaster hybrid male rescue gene causes inviability in male and female species hybridsD A Barbash
Department of Genetics, University of Cambridge, United Kingdom
Genetics 154:1747-71. 2000..melanogaster mothers. Implications of our findings for understanding Haldane's rule-the observation that hybrid breakdown is often specific to the heterogametic sex-are also discussed...
- Correlation between parental transcriptome and field data for the characterization of heterosis in Zea mays LAlexander Thiemann
Biocenter Klein Flottbek, University of Hamburg, 22609 Hamburg, Germany
Theor Appl Genet 120:401-13. 2010..The phenomenon of heterosis was characterized by the over- and underrepresentation of specific GO terms among heterosis-correlated genes...
- The ubiquitous mountain hare mitochondria: multiple introgressive hybridization in hares, genus LepusPaulo C Alves
Centro de Investigacao em Biodiversidade e Recursos Geneticos, Universidade do Porto, Campus Agrário de Vairão, 4485 661 Vairão, Portugal
Philos Trans R Soc Lond B Biol Sci 363:2831-9. 2008..Such high levels of introgressive hybridization should discourage attempts to revise hare taxonomy based solely on mtDNA...
- Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomeneRussell E Naisbit
The Galton Laboratory, Department of Biology, University College London, London NW1 2HE, United Kingdom
Genetics 161:1517-26. 2002..The effect of female sterility is comparable to that of selection against non-mimetic hybrids, while mate choice forms a much stronger barrier to gene transfer...
- Inferences from a rapidly moving hybrid zoneKanchon K Dasmahapatra
Department of Biology, University College London, United Kingdom
Evolution 56:741-53. 2002..Hybrid zone movement has rarely been considered likely in the past, but our results show that it may be more important in biogeography and evolution than generally realized...
- Aneuploidy and genetic variation in the Arabidopsis thaliana triploid responseIsabelle M Henry
Department of Biology, University of Washington, Seattle, Washington 98195 5325, USA
Genetics 170:1979-88. 2005..Thus, genetic variation was subject to selection contingent on the final ploidy and possibly acting during the protracted aneuploid phase...
- Interspecific hybridization in plant-associated fungi and oomycetes: a reviewC L Schardl
Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546 0091, USA
Mol Ecol 12:2861-73. 2003..Hybrid mutualists may also be better adapted to new hosts and can provide greater or more diverse benefits to host plants...
- Hybrid lethal systems in the Drosophila melanogaster species complex. II. The Zygotic hybrid rescue (Zhr) gene of D. melanogasterK Sawamura
Department of Genetics, Graduate University for Advanced Studies, National Institute of Genetics, Shizuoka, Japan
Genetics 133:307-13. 1993..A model is proposed to explain the genetic mechanisms of hybrid lethalities as well as the evolutionary pathways...
- Wolbachia-induced incompatibility precedes other hybrid incompatibilities in NasoniaS R Bordenstein
Department of Biology, The University of Rochester, New York 14627, USA
Nature 409:707-10. 2001....
- The maintenance of reproductive isolation in a mosaic hybrid zone between the fire-bellied toads Bombina bombina and B. variegataT H Vines
Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, Scotland
Evolution 57:1876-88. 2003..The hybrid zone may be approaching a state in which the gene pools are homogenized at all but the selected loci, not dissimilar from an early stage of sympatric divergence...
- A role for the mismatch repair system during incipient speciation in SaccharomycesD Greig
The Galton Laboratory, Department of Biology, University College London, London, UK
J Evol Biol 16:429-37. 2003..We show that these crosses are partially sterile and present evidence that the mismatch repair system is largely responsible for this sterility...
- Barrier to gene flow between two ecologically divergent Populus species, P. alba (white poplar) and P. tremula (European aspen): the role of ecology and life history in gene introgressionC Lexer
Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey TW9 3DS, UK
Mol Ecol 14:1045-57. 2005..alba N(e)c. 500-550; P. tremula N(e)c. 550-700). Our results indicate that hybrid zones will be valuable tools for studying the genetic architecture of the barrier to gene flow between these two ecologically divergent Populus species...
- Genetics of postzygotic isolation in Eucalyptus: whole-genome analysis of barriers to introgression in a wide interspecific cross of Eucalyptus grandis and E. globulusAlexander A Myburg
Department of Forestry, North Carolina State University, Raleigh, North Carolina 27695, USA
Genetics 166:1405-18. 2004....
- Intra-individual polymorphism in diploid and apomictic polyploid hawkweeds (Hieracium, Lactuceae, Asteraceae): disentangling phylogenetic signal, reticulation, and noiseJudith Fehrer
Institute of Botany, Academy of Sciences of the Czech Republic, Pruhonice, Czech Republic
BMC Evol Biol 9:239. 2009..Concentrating on the supposed major evolutionary units, we used nuclear ribosomal (ETS) and chloroplast (trnT-trnL) sequences in order to disentangle the phylogenetic relationships and to infer the origins of the polyploids...
- The accumulation of reproductive incompatibilities in African cichlid fishRike B Stelkens
Department of Ecology and Evolution, University of Lausanne, Biophore, CH 1015 Lausanne, Switzerland
Evolution 64:617-33. 2010..By quantifying the capacity to produce viable hybrids between allopatric, distantly related lineages our results also provide an upper divergence time limit for the "hybrid swarm origin" model of adaptive radiation...
- The rise and fall of the mountain hare (Lepus timidus) during Pleistocene glaciations: expansion and retreat with hybridization in the Iberian PeninsulaJ Melo-Ferreira
CIBIO, Centro de Investigacao em Biodiversidade e Recursos Geneticos, Universidade do Porto, Campus Agrário de Vairão, 4485 661 Vairão, Portugal
Mol Ecol 16:605-18. 2007..Whether a similar scenario explains the introgression into Iberian L. europaeus remains unclear but it is possible that it hybridized with already introgressed L. granatensis...
- Asymmetrical reinforcement and Wolbachia infection in DrosophilaJohn Jaenike
Department of Biology, University of Rochester, Rochester, New York, USA
PLoS Biol 4:e325. 2006..Given the widespread occurrence of Wolbachia among insects, it thus appears that there are multiple ways by which these endosymbionts may directly and indirectly contribute to reproductive isolation and speciation...
- From clonal to sexual hybrids: genetic recombination via triploids in all-hybrid populations of water frogsDitte G Christiansen
Ecology, Zoological Institute, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
Evolution 63:1754-68. 2009..esculentus calls for a change of the conventional view of hybridogens as clonally reproducing diploids. Rather, hybridogens can be independent sexually reproducing units with an evolutionary potential...
- Genetic and epigenetic consequences of recent hybridization and polyploidy in Spartina (Poaceae)Armel Salmon
UMR 118 INRA Agrocampus Rennes, Amelioration des Plantes et Biotechnologies Vegetales, Station de Génétique et Amélioration des Plantes, F 35653 Le Rheu, France
Mol Ecol 14:1163-75. 2005..Hybridization rather than genome doubling seems to have triggered most of the methylation changes observed in Spartina anglica...
- Genetic evidence for complex speciation of humans and chimpanzeesNick Patterson
Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
Nature 441:1103-8. 2006..These unexpected features would be explained if the human and chimpanzee lineages initially diverged, then later exchanged genes before separating permanently...
- Species relative abundance and direction of introgression in oaksO Lepais
INRA, UMR 1202 BIOGECO, Cestas, France
Mol Ecol 18:2228-42. 2009..In addition, we demonstrate a strong impact of species abundance on both hybridisation rate and introgression directionality...
- Adaptation by introgressionMichael L Arnold
Department of Genetics, University of Georgia, Athens, Georgia 30602, USA
J Biol 8:82. 2009..A recent analysis in BMC Evolutionary Biology of natural hybridization between an introduced and a native salamander reveals the mosaic nature of introgression, which is probably caused by a combination of selection and demography...
- Genetics and the fitness of hybridsJ M Burke
Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
Annu Rev Genet 35:31-52. 2001..In contrast, increased hybrid fitness can be most readily explained through the segregation of additive genetic factors, with epistasis playing a more limited role...
- Early events in speciation: polymorphism for hybrid male sterility in DrosophilaLaura K Reed
Department of Ecology and Evolutionary Biology and Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
Proc Natl Acad Sci U S A 101:9009-12. 2004..Because male sterility factors in hybrids between these species are not yet fixed within D. mojavensis, this system provides an invaluable opportunity to characterize the genetics of reproductive isolation at an early stage...
- Combined use of maternal, paternal and bi-parental genetic markers for the identification of wolf-dog hybridsC Vila
Department of Evolutionary Biology, Uppsala University, Sweden
Heredity (Edinb) 90:17-24. 2003..This finding confirms that inter-specific hybridization between wolves and dogs can occur in natural wolf populations. A possible correlation between hybridization and wolf population density and disturbance deserves further research...
- Hybridization rapidly reduces fitness of a native trout in the wildClint C Muhlfeld
US Geological Survey, Northern Rocky Mountain Science Center, Glacier National Park, West Glacier, MT 59936, USA
Biol Lett 5:328-31. 2009..This outbreeding depression suggests that even low levels of admixture may have negative effects on fitness in the wild and that policies protecting hybridized populations may need reconsideration...
- Two Dobzhansky-Muller genes interact to cause hybrid lethality in DrosophilaNicholas J Brideau
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
Science 314:1292-5. 2006..Rapidly evolving heterochromatic DNA sequences may be driving the evolution of this incompatibility gene...
- Song similarity predicts hybridization in flycatchersA Qvarnström
Animal Ecology, Department of Ecology and Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
J Evol Biol 19:1202-9. 2006..45% of 484 pairs; predicted 19.5%). Our results support the suggestion that song functions as the most important prezygotic isolation mechanism in many birds...
- An anomalous hybrid zone in DrosophilaAna Llopart
Department of Biological Sciences, University of Iowa, 215 Biology Building BB, Iowa City, Iowa 52242, USA
Evolution 59:2602-7. 2005..Third, there is a puzzling absence of hybrid females. We suggest several tentative explanations for the anomalies associated with this hybrid zone, but for the present they remain a mystery...
- Genes and speciationChung I Wu
Department of Ecology and Evolution, University of Chicago, Chicago, Illinois 60637, USA
Nat Rev Genet 5:114-22. 2004
- Extended Newick: it is time for a standard representation of phylogenetic networksGabriel Cardona
Department of Mathematics and Computer Science, University of the Balearic Islands, Palma de Mallorca, Spain
BMC Bioinformatics 9:532. 2008....
- Introduction. Extent, processes and evolutionary impact of interspecific hybridization in animalsKlaus Schwenk
Department of Ecology and Evolution, J W Goethe University Frankfurt am Main, 60054 Frankfurt am Main, Germany
Philos Trans R Soc Lond B Biol Sci 363:2805-11. 2008..Here we provide firstly a historic perspective of hybridization research, secondly a novel attempt to assess the extent of hybridization among animals and thirdly an overview of the reviews and case studies presented in this theme issue...
- Plant speciationLoren H Rieseberg
Department of Botany, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Science 317:910-4. 2007..Finally, species richness in plants is correlated with many biological and geohistorical factors, most of which increase ecological opportunities...
- Gene transposition as a cause of hybrid sterility in DrosophilaJohn P Masly
Department of Biology, University of Rochester, Rochester, NY 14627, USA
Science 313:1448-50. 2006..simulans lineage. Because of this transposition, a fraction of hybrids completely lack JYAlpha and are sterile, representing reproductive isolation without sequence evolution...
- Evidence for bimodal hybrid zones between two species of char (Pisces: Salvelinus) in northwestern North AmericaZ Redenbach
Department of Zoology, Native Fish Research Group, University of British Columbia, Vancouver, BC, Canada
J Evol Biol 16:1135-48. 2003..These traits may limit interspecific pairings because of size assortative pairing and size-dependent reproductive habitat use...
- Classical genetic and quantitative trait loci analyses of heterosis in a maize hybrid between two elite inbred linesElisabetta Frascaroli
Department of Agroenvironmental Sciences and Technologies, University of Bologna, 40127 Bologna, Italy
Genetics 176:625-44. 2007..Some chromosome regions presented overlaps of overdominant QTL for SW, PH, NK, and GY, suggesting pleiotropic effects on overall plant vigor...
- Adaptive gamete-recognition divergence in a hybridizing Mytilus populationStevan A Springer
Department of Biosciences, Behavioural Ecology Research Group, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada
Evolution 61:772-83. 2007..edulis in the East Atlantic, drove the divergence of Lysin-M7 in M. galloprovincialis...
- Parent-dependent loss of gene silencing during interspecies hybridizationCaroline Josefsson
Department of Biology, University of Washington, Seattle, Washington 98195, USA
Curr Biol 16:1322-8. 2006..We propose that the dosage-dependent regulation of chromatin could be a universal phenomenon affecting lethality in interspecies hybrids...
- Prevalence of interspecific hybrids amongst asexual fungal endophytes of grassesC D Moon
Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
Mol Ecol 13:1455-67. 2004..Therefore, the abundance of hybrid species among grass endophytes, and their prevalence in many host populations suggests a selective advantage of hybridization for the mutualistic endophytes...
- Standardization of HER-2/neu TestsJunqi Qian; Fiscal Year: 2001..and calibrators for quantitative immunohistochemistry, fluorescence in situ hybridization, and various genetic hybridization procedures...
- ELECTROPERMEABILIZATION/FUSION OF LIPID VESICLES & CELLSDavid Needham; Fiscal Year: 1993..These fundamental studies will find direct application in newly developing areas of biomedical and biochemical technologies, such as drug and hemoglobin encapsulation, antibody loading and genetic hybridization.
- GENETIC BASIS OF SPECIES DIFFERENCES IN DROSOPHILAJerry Coyne; Fiscal Year: 2009..We will perform laboratory studies of tolerance and preference to understand these anomalies. Our results may be relevant to understanding the origin of species in other animal groups, including humans. ..
- TRANSGRESSIVE SEGREGATION, ADAPTATION, AND SPECIATIONLoren Rieseberg; Fiscal Year: 2008..The proposed work represents an important step toward understanding the contribution of hybridization to adaptive evolution and speciation. ..
- Demographics and phylogeography of hybrid speciationJARED STRASBURG; Fiscal Year: 2007..abstract_text> ..
- Evolutionary genomics of new Drosophila genesDAVEN PRESGRAVES; Fiscal Year: 2004..The methods developed will be applicable in comparative analysis of other genomes, including those of humans and their primate relatives. ..
- Sperm recognition genesJulie Alipaz; Fiscal Year: 2004..All female specific transcripts will be explored for their possible involvement in gametic interactions and ultimately species divergence. ..
- Genetics Basis of Dietary Obesity in MiceJames Cheverud; Fiscal Year: 2009..These studies will increase our knowledge of the important physiological effects of dietary fat, including the genetic variants responsible for individual variations in response to a high fat diet. ..
- A Mouse Model for Complex Human DiseasesJames Cheverud; Fiscal Year: 2009..Backcrossing with SM/J will be used to narrow the QTL interval for strain loss and to produce a new strain, carrying the unusual phenotypes of SM/J without requiring enforced heterozygosity at the agouti locus. ..
- Genetic Environmental Relationship Between Bone Obesity and Leptin in MiceJames M Cheverud; Fiscal Year: 2010..This project will identify novel genes and physiological pathways affecting osteoporosis and examine how genetic and environmentally-based obesity affects bone mass, morphology and biomechanical function. ..
- GENETIC VARIATION IN MURINE LONG BONE GROWTH AND DEVELOPMENTJames M Cheverud; Fiscal Year: 2010..The outcome of these experiments will be a better understanding of the genetic, molecular, and cellular processes responsible for variation in limb growth with consequences for our understanding of pathologies of growth. ..
- GENE INTERACTION FOR BODY WEIGHT COMPONENTS IN MICEJames Cheverud; Fiscal Year: 2002..In addition to positional cloning of the QTLs, congenic strains will be formed for each QTL and will be tested, along with the LGxSM recombinant inbred strains for a variety of obesity-related traits. ..
- Epigenetic Regulation of Gene ExpressionRobert Martienssen; Fiscal Year: 2003..It is in a cross-disciplinary environment such as this that intellectual leaps occur and innovative ideas flourish. ..
- Transcriptional and genic basis of incipient speciationChung I Wu; Fiscal Year: 2008..We expect to identify a number of candidate "speciation genes,* and will carry out precise gene replacement (Rong and Golic 2000; Greenberg et al. 2003) to confirm their effects on the mating behavior. ..
- Noninvasive monitoring of physiological parameters in miceLARRY SANFORD; Fiscal Year: 2008..The proposed applications have particular significance for studies of behavior and sleep. [unreadable] [unreadable] [unreadable]..
- CMMI Human Subject Research Enhancement ProgramDavid Goldenberg; Fiscal Year: 2002..3.) Provide travel expenses and educational materials for IRB members, investigators, and Regulatory Affairs Office personnel to attend meetings for educational enhancement. ..
- Genetics of Longevity and Age-Sensitive Traits in MiceRichard Miller; Fiscal Year: 2008..abstract_text> ..
- Evolution of L1sw Retrotransposons in Teleost FishesDavid Duvernell; Fiscal Year: 2002..abstract_text> ..
- ENHANCED DEVELOPMENT OF THE XIPHOPHORUS MODEL SYSTEMRONALD WALTER; Fiscal Year: 2001....
- Studies on Influenza B Virus BM2 Protein Ion ChannelLAWRENCE PINTO; Fiscal Year: 2009....
- PHENOTYPICAL EXPRESSION OF ANXIETY AND SLEEPLARRY SANFORD; Fiscal Year: 2009....
- The Etiology of UV-Induced MelanomaDavid L Mitchell; Fiscal Year: 2010..From these studies we hope to define the effective solar wavelength boundaries of melanoma, identify the class of DNA damage critical to CMM and elucidate the role of DNA repair in tumor suppression. ..
- Genetic Determinants of Brain Structure and Disease Risk in SchizophreniaThomas H Wassink; Fiscal Year: 2010....
- THE XIPHOPHORUS GENETIC STOCK CENTERRONALD WALTER; Fiscal Year: 2006..abstract_text> ..
- MicroRNA evolution and species divergence in DrosophilaChung I Wu; Fiscal Year: 2010..A survey of the scope of microRNA repertoire and their rise and fall through evolution will be useful for understanding their roles in regulating the normal and aberrant phenotypes in human populations. ..
- The FIAT-ATF4 interaction and the control of bone massRene St Arnaud; Fiscal Year: 2010..These experiments will elucidate the molecular mechanisms through which FIAT regulates bone mass accrual in vivo. ..
- MUSCLE CAPILLARY GEOMETRY, FLOW, AND OXYGEN TRANSFERDavid Poole; Fiscal Year: 2001....
- NEUROBIOLOGICAL EFFECTS OF ALTERED MOTOR CONTROL IN REMLARRY SANFORD; Fiscal Year: 2001..These studies may lead to a better understanding of disorders of REM, such as REM behavior disorder, which, like REM-A, is characterized by overt behavior during sleep. ..
- Viral Encephalitis, Chemokines and SleepLARRY D contact SANFORD; Fiscal Year: 2010..Such understanding may provide insight that could lead to improved therapies and improved prognosis for infectious diseases. ..
- GENETICS OF AGE SENSITIVE TRAITS IN MICERichard Miller; Fiscal Year: 2003..At best, the program may permit the localization of loci that influence multiple age-sensitive domains and are thus plausible candidates for genes that regulate the rate of aging per se. ..
- 11th & 12th Conference on Cancer Therapy with Antibodies and ImmunoconjugatesDavid Goldenberg; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- The Cichlid Dentition Integrates Tooth Number and Tooth ShapeJEFFREY STREELMAN; Fiscal Year: 2007..Results may identify novel therapeutic targets for human dental disorders that warrant further testing in mammalian models. [unreadable] [unreadable] [unreadable]..
- A MULTI-FACETED SEARCH FOR AUTISM DISEASE GENESThomas Wassink; Fiscal Year: 2004..Taken together, the training plan and research proposal provide for a breadth of training, the potential for meaningful discovery, and support for the establishment of an independent research career. ..
- Cryptococcus gatti mating 1oci; mapping and gene studyVishnu Chaturvedi; Fiscal Year: 2004..abstract_text> ..
- WILD DERIVED MOUSE STOCKS--NEW MODELS FOR AGING RESEARCHRichard Miller; Fiscal Year: 2004....
- 9/10TH Conf./Cancer Therapy/Antibody/ImmunoconjugatesDavid Goldenberg; Fiscal Year: 2004..The conference chairman, Dr. Goldenberg, has secured two outstanding scientists as co-chairmen, Drs. Ralph Reisfeld (Scripps) and Edward Sausville (NCI). ..
- Protein Self-Assembly in Model MicroorganismsJames Hu; Fiscal Year: 2004..cerevisiae and E. coli) and important human pathogens (M. tuberculosis and A. fumigatus), and new drug targets based on protein-protein interactions. ..
- Parenchymal/Stem Cell Pathways for Salivary Gland RepairRobert Redman; Fiscal Year: 2003..abstract_text> ..
- Self recognition and signaling in plant reproductionJUNE NASRALLAH; Fiscal Year: 2005..abstract_text> ..
- 2005 Bones & Teeth Gordon ConferenceRene St Arnaud; Fiscal Year: 2005..These funds, if granted, will aid immeasurably in allowing the Gordon Research Conference to fulfill its function to stimulate further creativity in bone, cartilage and tooth research. ..
- Relevance of Herbal Products in TransplantationDilip Kittur; Fiscal Year: 2005..They will also uncover the mechanisms of action of Ginger and Milk thistle, determine if these herbal products interact with conventional immunosuppressive drugs, and potentially discover novel immunomodulatory agents. ..
- Angiocidal Effect of Cyclosporine in Cancer TherapyDilip Kittur; Fiscal Year: 2006..Our studies have the potential of discovering a novel, angiocidal effect of a commonly used drug. If successful, these studies will be translated expeditiously into clinical trials for the treatment of cancer. ..
- MOLECULAR GENETICS OF AUTISMThomas Wassink; Fiscal Year: 2006..The WNT2 findings will be further examined in two-independent patient samples. ..
- TRANSPOSON ACTIVE TRANSGENIC XIPHOPHORUSRONALD WALTER; Fiscal Year: 2003..abstract_text> ..
- Advances in Mineral Metabolism (AMM) meetingRene St Arnaud; Fiscal Year: 2006..unreadable] [unreadable] [unreadable] [unreadable]..
- High Throughput Assays for Ion Channel Activities of Influenza A & B VirusesLAWRENCE PINTO; Fiscal Year: 2006..These assays will make it possible to perform efficient searches for antiviral drugs against the M2 ion channels. [unreadable] [unreadable] [unreadable] [unreadable]..
- RESPIRATORY VIRUS ION CHANNELSLAWRENCE PINTO; Fiscal Year: 2007..5. In a separate set of experiments we will use a sensitive method to test the NB protein of influenza B virus for ion channel activity. [unreadable] [unreadable] [unreadable]..
- Molecular basis of reproductive isolation in DrosophilaAMANDA MOEHRING; Fiscal Year: 2007..simulans and its sibling species D. mauritiana and D. sechellia. Information from studies of Drosophila fertility can then potentially be applied to understanding the genetics of human fertility. ..
- Advances in Mineral Metabolism (AIMM) annual meetingRene St Arnaud; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..