peritoneal dialysis

Summary

Summary: Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.

Top Publications

  1. ncbi Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventions
    Luiz S Aroeira
    Unidad de Biologia Molecular, Hospital Universitario de la Princesa, C Diego de Leon 62, Madrid, Spain
    J Am Soc Nephrol 18:2004-13. 2007
  2. ncbi Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factor
    Luiz S Aroeira
    Servicio de Nefrologia, Hospital Universitario de la Princesa, Madrid, Spain
    Am J Kidney Dis 46:938-48. 2005
  3. ncbi Morphologic changes in the peritoneal membrane of patients with renal disease
    John D Williams
    Institute of Nephrology, University of Wales College of Medicine, Cardiff, United Kingdom
    J Am Soc Nephrol 13:470-9. 2002
  4. doi The pathophysiology of the peritoneal membrane
    Olivier Devuyst
    Division of Nephrology, UCL Medical School, 10 Avenue Hippocrate, B 1200 Brussels, Belgium
    J Am Soc Nephrol 21:1077-85. 2010
  5. doi Cu/Zn ratios are associated with nutritional status, oxidative stress, inflammation, and immune abnormalities in patients on peritoneal dialysis
    Chih Hung Guo
    Institute of Biomedical Nutrition, Hung Kuang University, Taichung 433, Taiwan, ROC
    Clin Biochem 44:275-80. 2011
  6. ncbi Basic mechanisms and clinical implications of peritoneal fibrosis
    Peter J Margetts
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Perit Dial Int 23:530-41. 2003
  7. pmc HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium
    Min A Yu
    Division of Nephrology, Ewha University School of Medicine, YangChun Ku, Seoul, Korea
    J Am Soc Nephrol 20:567-81. 2009
  8. pmc Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients
    Eric D Weinhandl
    Chronic Disease Research Group, Minneapolis, MN 55404, USA
    J Am Soc Nephrol 21:499-506. 2010
  9. ncbi Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA study
    J M Bargman
    Division of Nephrology, Toronto General Hospital, University of Toronto, 200 Elizabeth Street EN10 216, Toronto, Ontario M5G 2C4, Canada
    J Am Soc Nephrol 12:2158-62. 2001
  10. doi Tamoxifen is associated with lower mortality of encapsulating peritoneal sclerosis: results of the Dutch Multicentre EPS Study
    Mario R Korte
    Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands
    Nephrol Dial Transplant 26:691-7. 2011

Detail Information

Publications301 found, 100 shown here

  1. ncbi Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventions
    Luiz S Aroeira
    Unidad de Biologia Molecular, Hospital Universitario de la Princesa, C Diego de Leon 62, Madrid, Spain
    J Am Soc Nephrol 18:2004-13. 2007
    b>Peritoneal dialysis (PD) is a form of renal replacement and is based on the use of the peritoneum as a semipermeable membrane across which ultrafiltration and diffusion take place...
  2. ncbi Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factor
    Luiz S Aroeira
    Servicio de Nefrologia, Hospital Universitario de la Princesa, Madrid, Spain
    Am J Kidney Dis 46:938-48. 2005
    During peritoneal dialysis (PD), the peritoneum is exposed to bioincompatible dialysis fluids that cause epithelial-to-mesenchymal transition of mesothelial cells, fibrosis, and angiogenesis...
  3. ncbi Morphologic changes in the peritoneal membrane of patients with renal disease
    John D Williams
    Institute of Nephrology, University of Wales College of Medicine, Cardiff, United Kingdom
    J Am Soc Nephrol 13:470-9. 2002
    This study examined the morphologic features of the parietal peritoneal membranes of 130 patients undergoing peritoneal dialysis (PD) and compared them with the features of the peritoneal membranes of normal individuals, uremic ..
  4. doi The pathophysiology of the peritoneal membrane
    Olivier Devuyst
    Division of Nephrology, UCL Medical School, 10 Avenue Hippocrate, B 1200 Brussels, Belgium
    J Am Soc Nephrol 21:1077-85. 2010
    The development of peritoneal dialysis (PD) as a successful therapy has and still depends on experimental models to test and understand critical pieces of pathophysiology...
  5. doi Cu/Zn ratios are associated with nutritional status, oxidative stress, inflammation, and immune abnormalities in patients on peritoneal dialysis
    Chih Hung Guo
    Institute of Biomedical Nutrition, Hung Kuang University, Taichung 433, Taiwan, ROC
    Clin Biochem 44:275-80. 2011
    We evaluated the relationship of the plasma copper/zinc (Cu/Zn) ratio with nutritional status, inflammation, oxidative stress, and immune function in peritoneal dialysis patients.
  6. ncbi Basic mechanisms and clinical implications of peritoneal fibrosis
    Peter J Margetts
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Perit Dial Int 23:530-41. 2003
    ..Clinical trials to assess the role of prevention of peritoneal injury using biocompatible solutions and treatments targeted directly at peritoneal fibrosis will be important, but challenging to design and carry out...
  7. pmc HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium
    Min A Yu
    Division of Nephrology, Ewha University School of Medicine, YangChun Ku, Seoul, Korea
    J Am Soc Nephrol 20:567-81. 2009
    Over time, peritoneal dialysis results in functional and structural alterations of the peritoneal membrane, but the underlying mechanisms and whether these changes are reversible are not completely understood...
  8. pmc Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients
    Eric D Weinhandl
    Chronic Disease Research Group, Minneapolis, MN 55404, USA
    J Am Soc Nephrol 21:499-506. 2010
    Contemporary comparisons of mortality in matched hemodialysis and peritoneal dialysis patients are lacking...
  9. ncbi Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA study
    J M Bargman
    Division of Nephrology, Toronto General Hospital, University of Toronto, 200 Elizabeth Street EN10 216, Toronto, Ontario M5G 2C4, Canada
    J Am Soc Nephrol 12:2158-62. 2001
    Studies of the adequacy of peritoneal dialysis and recommendations have assumed that renal and peritoneal clearances are comparable and therefore additive. The CANUSA data were reanalyzed in an effort to address this assumption...
  10. doi Tamoxifen is associated with lower mortality of encapsulating peritoneal sclerosis: results of the Dutch Multicentre EPS Study
    Mario R Korte
    Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands
    Nephrol Dial Transplant 26:691-7. 2011
    Encapsulating peritoneal sclerosis (EPS) is a serious complication of peritoneal dialysis (PD) with an increasing incidence...
  11. ncbi Recurrent and atypical posterior reversible encephalopathy syndrome in a child with peritoneal dialysis
    Ilknur Girişgen
    Department of Pediatrics, Adnan Menderes University Faculty of Medicine, Aydm, Turkey
    Turk J Pediatr 52:416-9. 2010
    ..this article, we present recurrent atypical PRES in a hypertensive child with end-stage renal disease on a peritoneal dialysis program as a rare case and we discuss recurrence...
  12. ncbi Survival analysis: comparing peritoneal dialysis and hemodialysis in Taiwan
    Chiu Ching Huang
    Department of Medicine and Biostatistics Center, China Medical University, Taiwan
    Perit Dial Int 28:S15-20. 2008
    Comparisons of survival in patients on peritoneal dialysis (PD) and on hemodialysis (HD) have been conducted in many Western countries, but publications on this subject in Asian populations are scarce...
  13. pmc Serum albumin as a predictor of mortality in peritoneal dialysis: comparisons with hemodialysis
    Rajnish Mehrotra
    Division of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    Am J Kidney Dis 58:418-28. 2011
    ..Whether the threshold level of serum albumin at which mortality risk increases in peritoneal dialysis (PD) patients is the same as for hemodialysis (HD) patients has not been studied.
  14. pmc Broadening Options for Long-term Dialysis in the Elderly (BOLDE): differences in quality of life on peritoneal dialysis compared to haemodialysis for older patients
    Edwina A Brown
    Imperial College Kidney and Transplant Institute, Hammersmith Hospital, London, UK
    Nephrol Dial Transplant 25:3755-63. 2010
    ..Little is, however, known about differences in QOL on haemodialysis (HD) and peritoneal dialysis (PD) in older age groups. Randomising patients to either modality to assess outcomes is not feasible.
  15. doi Frequencies of hepatitis B and C infections among haemodialysis and peritoneal dialysis patients in Asia-Pacific countries: analysis of registry data
    David W Johnson
    Australia and New Zealand Dialysis and Transplant Registry, Discipline of Public Health, University of Adelaide, Adelaide, Australia
    Nephrol Dial Transplant 24:1598-603. 2009
    ..The aim of the present investigation was to evaluate the rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections in peritoneal dialysis (PD) and haemodialysis (HD) patients in the Asia-Pacific region.
  16. pmc Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysis
    Gareth W Roberts
    Institute of Nephrology, School of Medicine, Cardiff University, Heath Park, Cardiff, Wales, UK
    J Am Soc Nephrol 20:1895-900. 2009
    ..peritonitis adversely affect the structure and function of the peritoneal membrane in patients treated with peritoneal dialysis (PD), but the underlying mechanisms are not well understood...
  17. ncbi Body composition, hydration, and related parameters in hemodialysis versus peritoneal dialysis patients
    Isabel Devolder
    Renal Division, University Hospital Ghent, Ghent, Belgium
    Perit Dial Int 30:208-14. 2010
    ..A new multifrequency bioimpedance tool has recently been validated. This study compares volume status in peritoneal dialysis (PD) and hemodialysis (HD) patients in a single center.
  18. ncbi The influence of dialysate calcium on progression of arterial stiffness in peritoneal dialysis patients
    Meltem Sezis Demirci
    Division of Nephrology, Ege University School of Medicine, Izmir, Turkey
    Perit Dial Int 29:S15-7. 2009
    One of the origins of cardiovascular disease in dialysis patients is arterial stiffness. The aim of our study was to assess the relationship between the calcium content of peritoneal dialysis (PD) solution and arterial stiffness.
  19. ncbi Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam
    Nguyen Hoan Phu
    Center for Tropical Diseases, Center for Tropical Diseases, Cho Quan Hospital, Ho Chi Minh City, Vietnam
    N Engl J Med 347:895-902. 2002
    In some parts of the world, peritoneal dialysis is widely used for renal replacement in acute renal failure...
  20. doi PPAR-γ agonist rosiglitazone protects peritoneal membrane from dialysis fluid-induced damage
    Pilar Sandoval
    Unidad de Biologia Molecular, Hospital Universitario de la Princesa, Madrid, Spain
    Lab Invest 90:1517-32. 2010
    Exposure to non-physiological solutions during peritoneal dialysis (PD) produces structural alterations to the peritoneal membrane and ultrafiltration dysfunction...
  21. ncbi Encapsulating peritoneal sclerosis--a clinician's approach to diagnosis and medical treatment
    Hidetomo Nakamoto
    Department of Nephrology, Tokorozawa Kidney Clinic, Tokorozawa, Japan
    Perit Dial Int 25:S30-8. 2005
    Encapsulating peritoneal sclerosis (EPS) is recognized as a serious complication of continuous peritoneal dialysis. A preliminary diagnosis of EPSis usually based on clinical signs and symptoms, which commonly include abdominal pain, ..
  22. ncbi Peritonitis remains the major clinical complication of peritoneal dialysis: the London, UK, peritonitis audit 2002-2003
    Andrew Davenport
    UCL Centre for Nephrology, Royal Free and University College Medical School, London, United Kingdom
    Perit Dial Int 29:297-302. 2009
    Over the past two decades, the rate of peritonitis in patients treated by peritoneal dialysis (PD) has been significantly reduced...
  23. ncbi Predictors of loss of residual renal function among new dialysis patients
    L M Moist
    Department of Medicine, University of Western Ontario, London, Canada
    J Am Soc Nephrol 11:556-64. 2000
    ..to determine the predictors of RRF loss in a national random sample of patients initiating hemodialysis and peritoneal dialysis. The study controlled for baseline variables and included major predictors...
  24. pmc Geographic and educational factors and risk of the first peritonitis episode in Brazilian Peritoneal Dialysis study (BRAZPD) patients
    Luis C Martin
    Department of Internal Medicine, Botucatu Medical School, 18618 000 Botucatu, Sao Paulo, Brazil
    Clin J Am Soc Nephrol 6:1944-51. 2011
    Peritonitis remains as the most frequent cause of peritoneal dialysis (PD) failure, impairing patient's outcome...
  25. ncbi Peritoneal dialysis-associated peritonitis in Scotland (1999-2002)
    David Kavanagh
    The Scottish Renal Registry, Royal Infirmary, Castle Street, Glasgow G4 0SF, UK
    Nephrol Dial Transplant 19:2584-91. 2004
    Peritonitis is a major complication of peritoneal dialysis (PD). We have performed a national study of all patients on PD in Scotland over a 3...
  26. ncbi Initial glucose load predicts technique survival in patients on chronic peritoneal dialysis
    Hon Yen Wu
    Department of Internal Medicine, Yun Lin branch, National Taiwan University Hospital, Yun Lin, Taiwan
    Am J Nephrol 28:765-71. 2008
    A high glucose content in peritoneal dialysis (PD) solution may result in unfavorable changes on peritoneal character and worsened metabolic profiles...
  27. ncbi Peritoneal dialysis patient survival: a comparison between a Swedish and a Korean centre
    Sung Hee Chung
    Hyonam Kidney Laboratory, Soon Chun Hyang University, 657 Hannam Dong, Yongsan Ku, Seoul 140 743, Korea
    Nephrol Dial Transplant 20:1207-13. 2005
    Dialysis patient mortality remains high, and this high mortality may be due to many factors. In peritoneal dialysis (PD) patients, old age, co-morbid diseases, malnutrition, low residual renal function (RRF) and a high peritoneal ..
  28. ncbi Ex vivo analysis of dialysis effluent-derived mesothelial cells as an approach to unveiling the mechanism of peritoneal membrane failure
    Manuel López-Cabrera
    Unidad de Biologia Molecular, Hospital Universitario de la Princesa, Diego de Leon, 62, 28006 Madrid, Spain
    Perit Dial Int 26:26-34. 2006
    During peritoneal dialysis (PD), the peritoneum is exposed to bioincompatible dialysis fluids, which causes progressive fibrosis and angiogenesis and, ultimately, ultrafiltration failure...
  29. ncbi Higher rate and earlier peritonitis in Aboriginal patients compared to non-Aboriginal patients with end-stage renal failure maintained on peritoneal dialysis in Australia: analysis of ANZDATA
    Wai H Lim
    Renal Unit, Queen Elizabeth Hospital, Adelaide, South Australia, Australia
    Nephrology (Carlton) 10:192-7. 2005
    Aboriginal patients maintained on peritoneal dialysis (PD) have a higher rate of technique failure than any other racial group in Australia...
  30. ncbi Cardiovascular problems in dialysis patients: impact on survival
    Manavjot S Sidhu
    Department of Internal Medicine, University of Missouri, Columbia, Missouri 65212, USA
    Adv Perit Dial 26:47-52. 2010
    ..from clinical trials, data from randomized controlled trials regarding outcomes in patients undergoing peritoneal dialysis are almost absent...
  31. pmc Global trends in rates of peritoneal dialysis
    Arsh K Jain
    Division of Nephrology, University of Western Ontario, London, Canada
    J Am Soc Nephrol 23:533-44. 2012
    Although there is a perception that the use of peritoneal dialysis is declining worldwide, compilations of global data are unavailable to test this hypothesis...
  32. pmc Inflammatory cytokines, angiogenesis, and fibrosis in the rat peritoneum
    Peter J Margetts
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    Am J Pathol 160:2285-94. 2002
    Peritonitis, a common complication of peritoneal dialysis, is followed by acute changes in the function of the peritoneum. The role of inflammatory cytokines in these processes is not clearly identified...
  33. pmc Cancer in patients on chronic dialysis in Korea
    Jung Eun Lee
    Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
    J Korean Med Sci 24:S95-S101. 2009
    ..3%) out of 4,562 end-stage renal disease (ESRD) patients maintained on hemodialysis (HD) or peritoneal dialysis (PD) at Yonsei University Health System from 1996 to 2005...
  34. pmc Encapsulating peritoneal sclerosis in the new millennium: a national cohort study
    Michaela C Brown
    Scottish Renal Registry, Royal Infirmary, Glasgow, UK
    Clin J Am Soc Nephrol 4:1222-9. 2009
    The study aim was to establish the incidence and characterize all encapsulating peritoneal sclerosis (EPS) cases in patients treated by peritoneal dialysis (PD).
  35. doi Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis
    Hideki Yokoi
    Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Kidney Int 81:160-9. 2012
    Long-term peritoneal dialysis induces peritoneal fibrosis with submesothelial fibrotic tissue. Although angiogenesis and inflammatory mediators are involved in peritoneal fibrosis, precise molecular mechanisms are undefined...
  36. ncbi Peritoneal mast cells in peritoneal dialysis patients, particularly in encapsulating peritoneal sclerosis patients
    Dominik M Alscher
    Department of Internal Medicine, Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    Am J Kidney Dis 49:452-61. 2007
    ..that increased mast cell numbers contribute substantially to the fibrosis often seen in the peritoneum of peritoneal dialysis (PD) patients, particularly those with encapsulating peritoneal fibrosis (EPS)...
  37. ncbi The effects of renin-angiotensin system inhibition on regression of encapsulating peritoneal sclerosis
    Devrim Bozkurt
    Department of Nephrology, Ege University, Izmir, Turkey
    Perit Dial Int 28:S38-42. 2008
    ..b>Peritoneal dialysis (PD) patients rarely develop EPS, a severe life-threatening condition of unknown pathogenesis...
  38. ncbi The role of the TGF/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutions
    Qiang Yao
    Divisions of Baxter Novum and Renal Medicine, Department of Clinical Science, Karolinska Institutet, Stockholm, Sweden
    Nephron Exp Nephrol 109:e71-8. 2008
    b>Peritoneal dialysis (PD) solutions contribute to peritoneal membrane damage...
  39. ncbi Peritoneal changes after exposure to sterile solutions by catheter
    Michael F Flessner
    Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
    J Am Soc Nephrol 18:2294-302. 2007
    ..These findings confirm the hypothesis that the presence of a PC catheter increases inflammatory response to sterile solutions as evidenced by the structural and functional changes in the peritoneal barrier...
  40. ncbi Mesothelial cells
    Susan Yung
    Department of Medicine, University of Hong Kong, Hong Kong SAR, PR China
    Perit Dial Int 27:S110-5. 2007
    The introduction of peritoneal dialysis (PD) as a modality of renal replacement therapy has provoked much interest in the biology of the peritoneal mesothelial cell...
  41. ncbi Cost comparison of peritoneal dialysis versus hemodialysis in end-stage renal disease
    Ariel Berger
    Policy Analysis, Inc, Four Davis Ct, Brookline, MA 02445, USA
    Am J Manag Care 15:509-18. 2009
    To compare healthcare utilization and costs in patients with end-stage renal disease (ESRD) beginning peritoneal dialysis (PD) or hemodialysis (HD).
  42. ncbi Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cells
    Sonja Mandl-Weber
    Nephrologisches Zentrum, Medizinische Klinik und Poliklinik Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
    Kidney Int 61:570-8. 2002
    Vascular endothelial growth factor (VEGF) was recently found in peritoneal effluents of peritoneal dialysis (PD) patients...
  43. ncbi Severe vitamin D deficiency in chronic renal failure patients on peritoneal dialysis
    H Taskapan
    Inonu University Medical School, Department of Medicine, Division of Nephrology, Malatya, Turkey
    Clin Nephrol 66:247-55. 2006
    The aim of this study was to evaluate the prevalence of vitamin D deficiency in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with various demographic and renal osteodystrophy markers.
  44. ncbi Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis
    J Ni
    Division of Nephrology and Department of Pathology, UCL Medical School, Brussels, Belgium
    Kidney Int 69:1518-25. 2006
    ..of the implication of AQP1 in solute-free water transport, sodium sieving, and ultrafiltration (UF) during peritoneal dialysis (PD) is lacking, and the effects of its deletion on the structure of the membrane are unknown...
  45. ncbi Increases in serum leptin levels during peritoneal dialysis are associated with inflammation and a decrease in lean body mass
    P Stenvinkel
    Division of Renal Medicine, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    J Am Soc Nephrol 11:1303-9. 2000
    ..elevated leptin levels have been documented in uremic patients, especially in those who are treated by peritoneal dialysis (PD)...
  46. ncbi Serum matrix metalloproteinases MMP-2 and MMP-3 levels in dialysis patients vary independently of CRP and IL-6 levels
    Gloria A Preston
    Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Nephron 92:817-23. 2002
    Patients on chronic hemodialysis or peritoneal dialysis often develop an inflammatory state that causes morbidity and mortality...
  47. ncbi Sodium removal in patients undergoing CAPD and automated peritoneal dialysis
    Ana Rodriguez-Carmona
    Division of Nephrology, Hospital Juan Canalejo, A Coruna, Spain
    Perit Dial Int 22:705-13. 2002
    To compare sodium removal in continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) patients, and to identify the main factors that modify Na removal in clinical practice in these patients.
  48. ncbi Impact of ACE inhibitors and AII receptor blockers on peritoneal membrane transport characteristics in long-term peritoneal dialysis patients
    Inna Kolesnyk
    Division of Nephrology, Academic Medical Center, Amsterdam, The Netherlands
    Perit Dial Int 27:446-53. 2007
    Long-term peritoneal dialysis (PD) may lead to peritoneal fibrosis and ultrafiltration failure. The latter occurs due to high solute transport rates and diabetiform peritoneal sclerosis...
  49. ncbi Computed tomographic findings characteristic for encapsulating peritoneal sclerosis: a case-control study
    Anniek Vlijm
    Department of Medicine, University of Amsterdam, Amsterdam, The Netherlands
    Perit Dial Int 29:517-22. 2009
    ..To establish CT findings characteristic for EPS, we compared CT findings between EPS patients and long-term peritoneal dialysis (PD) patients without EPS.
  50. pmc Glycemic control and survival in peritoneal dialysis patients with diabetes mellitus
    Uyen Duong
    Harold Simmons Center for Chronic Disease Research and Epidemiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90509 2910, USA
    Clin J Am Soc Nephrol 6:1041-8. 2011
    The optimal target for glycemic control has not been established for diabetic peritoneal dialysis (PD) patients.
  51. ncbi Oral paricalcitol for the treatment of secondary hyperparathyroidism in patients on hemodialysis or peritoneal dialysis
    Edward A Ross
    Division of Nephrology, Hypertension, and Transplantation, University of Florida, Gainesville, FL 32610 0224, USA
    Am J Nephrol 28:97-106. 2008
    ..This study investigates the effects of oral paricalcitol to reduce PTH in patients receiving chronic HD and peritoneal dialysis (PD).
  52. ncbi Charlson comorbidity index as a predictor of outcomes in incident peritoneal dialysis patients
    L Fried
    Renal Section, VA Pittsburgh Healthcare System, and Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Kidney Dis 37:337-42. 2001
    ..The purpose of this study was to examine the usefulness of the CCI as a predictor in incident peritoneal dialysis (PD) patients and to examine whether it was a better predictor than simply the number of comorbid ..
  53. ncbi Effect of fluid and sodium removal on mortality in peritoneal dialysis patients
    K Ates
    Ankara University Medical School, Ibn i Sina Hospital, Department of Nephrology, Ankara, Turkey
    Kidney Int 60:767-76. 2001
    Effect of fluid and sodium removal on mortality in peritoneal dialysis patients.
  54. ncbi NT-proBNP, fluid volume overload and dialysis modality are independent predictors of mortality in ESRD patients
    Ramon Paniagua
    Unidad de Investigacion Medica en Enfermedades Nefrologicas, Hospital de Especialidades, CMN Siglo XXI, Mexico City
    Nephrol Dial Transplant 25:551-7. 2010
    ..It has been suggested that continuous ambulatory peritoneal dialysis (CAPD), automated peritoneal dialysis (APD) and haemodialysis (HD) may have different effects on fluid ..
  55. ncbi Survival advantages of obesity in dialysis patients
    Kamyar Kalantar-Zadeh
    Division of Nephrology and Hypertension, Los Angeles Biomedical Institute at Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
    Am J Clin Nutr 81:543-54. 2005
    ..or dialysis-risk-paradox is relatively consistent in MHD patients, studies in CKD patients undergoing peritoneal dialysis have yielded mixed results...
  56. ncbi The progression and impact of vascular calcification in peritoneal dialysis patients
    Adriano Luiz Ammirati
    Nephrology Division, Federal University of Sao Paulo, 282 Pedro de Toledo Street, São Paulo 04039 000, Brazil
    Perit Dial Int 27:340-6. 2007
    ..Little information is available regarding peritoneal patients...
  57. ncbi Cardiovascular risk in the peritoneal dialysis patient
    Raymond T Krediet
    Division of Nephrology, Department of Medicine, Academic Medical Centre University of Amsterdam, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Nat Rev Nephrol 6:451-60. 2010
    Cardiovascular death is the most frequent cause of death in patients on peritoneal dialysis. Risk factors for cardiovascular death in these patients include those that affect the general population as well as those related to end-stage ..
  58. doi Similar outcomes with hemodialysis and peritoneal dialysis in patients with end-stage renal disease
    Rajnish Mehrotra
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Arch Intern Med 171:110-8. 2011
    The annual payer costs for patients treated with peritoneal dialysis (PD) are lower than with hemodialysis (HD), but in 2007, only 7% of dialysis patients in the United States were treated with PD...
  59. ncbi Continuous peritoneal dialysis-associated peritonitis: a review and current concepts
    Laura Troidle
    New Haven CAPD, Renal Research Institute, New Haven, Connecticut, USA
    Semin Dial 16:428-37. 2003
    The percentage of end-stage renal disease (ESRD) patients in the United States maintained on continuous peritoneal dialysis (CPD) therapy is decreasing...
  60. ncbi The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane
    John D Williams
    Institute of Nephrology, University Hospital of Wales College of Medicine, Heath Park, Cardiff, Wales, UK
    Kidney Int 66:408-18. 2004
    Although peritoneal dialysis (PD) is a widely accepted form of renal replacement therapy (RRT), concerns remain regarding the bioincompatible nature of standard PD fluid...
  61. ncbi Peritoneal dialysis in the 21st century: an analysis of current problems and future developments
    Ram Gokal
    Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom
    J Am Soc Nephrol 13:S104-16. 2002
  62. ncbi Peritoneal glucose exposure and changes in membrane solute transport with time on peritoneal dialysis
    S J Davies
    Department of Nephrology, North Staffordshire Hospitals Trust, Stoke on Trent, United Kingdom
    J Am Soc Nephrol 12:1046-51. 2001
    Peritoneal solute transport increases with time on treatment in a proportion of peritoneal dialysis (PD) patients, contributing to ultrafiltration failure...
  63. ncbi Changes in quality of life during hemodialysis and peritoneal dialysis treatment: generic and disease specific measures
    Albert W Wu
    Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Am Soc Nephrol 15:743-53. 2004
    ..20 yr of use, relative differences in health-related quality of life (HRQOL) between hemodialysis (HD) and peritoneal dialysis (PD) are not clearly known...
  64. ncbi The differential impact of risk factors on mortality in hemodialysis and peritoneal dialysis
    Edward F Vonesh
    Baxter Healthcare Corporation, Applied Statistics Center, Round Lake, Illinois 60073, USA
    Kidney Int 66:2389-401. 2004
    ..Trends in available data indicate the relative risk of death with hemodialysis (HD) compared to peritoneal dialysis (PD) varies by time on dialysis and the presence of various risk factors...
  65. ncbi Icodextrin improves the fluid status of peritoneal dialysis patients: results of a double-blind randomized controlled trial
    Simon J Davies
    University Hospital of North Staffordshire, Stoke on Trent, England
    J Am Soc Nephrol 14:2338-44. 2003
    Worsening fluid balance results in reduced technique and patient survival in peritoneal dialysis. Under these conditions, the glucose polymer icodextrin is known to enhance ultrafiltration in the long dwell...
  66. ncbi Mortality and technique failure in patients starting chronic peritoneal dialysis: results of The Netherlands Cooperative Study on the Adequacy of Dialysis. NECOSAD Study Group
    K J Jager
    Department of Nephrology, Academic Medical Center, University of Amsterdam, The Netherlands
    Kidney Int 55:1476-85. 1999
    ..The aim of this study was to determine the relative importance of baseline patient and treatment characteristics to mortality and technique failure in patients starting peritoneal dialysis.
  67. doi The relationship between the soluble Klotho protein and the residual renal function among peritoneal dialysis patients
    Tetsu Akimoto
    Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
    Clin Exp Nephrol 16:442-7. 2012
    ..The purpose of the present study was to determine the relationship between the soluble form of Klotho and renal function in chronic peritoneal dialysis (PD) patients, a relationship which remains poorly understood.
  68. doi Prospective randomized study for comparison of open surgery with laparoscopic-assisted placement of Tenckhoff peritoneal dialysis catheter--a single center experience and literature review
    Shyh Chuan Jwo
    Division of General Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC
    J Surg Res 159:489-96. 2010
    The ideal method for catheter placement in patients undergoing peritoneal dialysis remains debatable. This prospective study intends to clarify whether laparoscopic assisted percutaneous puncture is superior to open surgery.
  69. ncbi Mini-laparoscopy-assisted placement of Tenckhoff catheters: an improved technique to facilitate peritoneal dialysis
    Charlotte A Batey
    Division of Urology, Department of Surgery, University of Kentucky, 800 Rose Street, Lexington, KY 40536 0084, USA
    J Endourol 16:681-4. 2002
    Despite its overall efficacy and patient satisfaction with it, peritoneal dialysis has a history of significant complications, which has contributed to the evolution in the technique from open laparotomy to minimally invasive placement ..
  70. ncbi Laparoscopic-assisted peritoneal dialysis catheter placement: a microinvasive technique
    Sergio A Carrillo
    Department of Surgery, University of Louisville, Louisville, KY 40202, USA
    Surg Endosc 21:825-9. 2007
    b>Peritoneal dialysis is an alternate form of dialysis for patients with end-stage renal disease (ESRD)...
  71. doi Remote indigenous peritoneal dialysis patients have higher risk of peritonitis, technique failure, all-cause and peritonitis-related mortality
    Wai H Lim
    Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia
    Nephrol Dial Transplant 26:3366-72. 2011
    ..Because many indigenous patients live in remote areas, peritoneal dialysis (PD) is often preferred...
  72. ncbi Recent concepts in the molecular biology of the peritoneal membrane - implications for more biocompatible dialysis solutions
    Siska Mortier
    Renal Division, University Hospital, De Pintelaan, Ghent, Belgium
    Blood Purif 21:14-23. 2003
    ..The structural and functional alterations in the membrane in long-term peritoneal dialysis are thought to be the consequence of the toxicity of glucose, either directly or indirectly through the ..
  73. doi Plasma levels of soluble receptor for advanced glycation end products (sRAGE) and proinflammatory ligand for RAGE (EN-RAGE) are associated with carotid atherosclerosis in patients with peritoneal dialysis
    Jwa Kyung Kim
    Department of Internal Medicine and Kidney Research Institute, Hallym University College of Medicine, Anyang, Republic of Korea
    Atherosclerosis 220:208-14. 2012
    ..We determined the levels of sRAGE and EN-RAGE in peritoneal dialysis (PD) patients and evaluated their relationship with carotid atherosclerosis.
  74. doi Encapsulating peritoneal sclerosis: the state of affairs
    Mario R Korte
    Albert Schweitzer Hospital, Department of Internal Medicine, PO Box 444, 3300 AK Dordrecht, The Netherlands
    Nat Rev Nephrol 7:528-38. 2011
    Encapsulating peritoneal sclerosis (EPS) is a severe complication of long-term peritoneal dialysis (PD) with a 50% mortality rate...
  75. ncbi Can increased dietary fibre reduce laxative requirement in peritoneal dialysis patients?
    Debbie Sutton
    Wessex Renal and Transplant Service, Queen Alexandra Hospital, Portsmouth, UK
    J Ren Care 33:174-8. 2007
    Constipation is an important cause of technique failure and poor dialysis efficiency in Peritoneal Dialysis (PD) patients. A review of patient notes on our unit revealed 43% reported difficulties associated with constipation...
  76. ncbi Polymicrobial peritonitis in peritoneal dialysis patients in Australia: predictors, treatment, and outcomes
    Katherine Barraclough
    Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
    Am J Kidney Dis 55:121-31. 2010
    The study aim was to examine the frequency, predictors, treatment, and clinical outcomes of peritoneal dialysis-associated polymicrobial peritonitis.
  77. ncbi Correlations of lean body mass with nutritional indicators and mortality in patients on peritoneal dialysis
    J Dong
    Renal Division, Department of Medicine, Peking University First Hospital, Beijing, PR China
    Kidney Int 73:334-40. 2008
    ..kinetics, anthropometry, and biometric impedance in 210 incident Chinese patients on continuous ambulatory peritoneal dialysis. The study was started in the third month of dialysis and the patients were followed for an average of 29 ..
  78. pmc A study of the clinical and biochemical profile of peritoneal dialysis fluid low in glucose degradation products
    Kar Neng Lai
    Department of Medicine, The University of Hong Kong, Hong Kong SAR, PR China
    Perit Dial Int 32:280-91. 2012
    Although peritoneal dialysis (PD) is a widely accepted form of renal replacement therapy, concerns remain regarding the bioincompatible nature of standard PD fluid (PDF)...
  79. ncbi Staphylococcus aureus peritonitis complicates peritoneal dialysis: review of 245 consecutive cases
    Cheuk Chun Szeto
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Clin J Am Soc Nephrol 2:245-51. 2007
    Peritonitis that is caused by Staphylococcus aureus is a serious complication in peritoneal dialysis (PD), but the clinical course of PD-related S. aureus peritonitis remains unclear. All of the S...
  80. pmc Selection bias explains apparent differential mortality between dialysis modalities
    Robert R Quinn
    University of Calgary, Foothills Medical Centre, Calgary, Alberta, T2N 2T9 Canada
    J Am Soc Nephrol 22:1534-42. 2011
    The relative risk of death for patients treated with peritoneal dialysis compared with those treated with hemodialysis appears to change with duration of dialysis therapy...
  81. pmc Relationship between dialysis modality and mortality
    Stephen P McDonald
    Renal Unit, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South SA 5011, Australia
    J Am Soc Nephrol 20:155-63. 2009
    Mortality differences between peritoneal dialysis (PD) and hemodialysis (HD) are widely debated...
  82. pmc Association of dialysis modality and cardiovascular mortality in incident dialysis patients
    David W Johnson
    Australia and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia
    Clin J Am Soc Nephrol 4:1620-8. 2009
    The aim of the investigation presented here was to compare the rates, causes, and timing of cardiovascular (CV) death in incident peritoneal dialysis (PD) and hemodialysis (HD) patients.
  83. ncbi Predictors, treatment, and outcomes of non-Pseudomonas Gram-negative peritonitis
    Elizabeth M Jarvis
    Australia and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia
    Kidney Int 78:408-14. 2010
    Non-Pseudomonas Gram-negative (NPGN) peritonitis is a frequent, serious complication of peritoneal dialysis; however, previous reports have been limited to small, single-center studies...
  84. ncbi Three purse-string sutures allow immediate start of peritoneal dialysis with a low incidence of leakage
    Bernd G Stegmayr
    Department of Internal Medicine, University Hospital, Umea, Sweden
    Semin Dial 16:346-8. 2003
    b>Peritoneal dialysis (PD) depends to a great extent on a well-functioning dialysis catheter...
  85. ncbi Encapsulating peritoneal sclerosis in Japan: a prospective, controlled, multicenter study
    Hideki Kawanishi
    Tsuchiya General Hospital, Hiroshima, Japan
    Am J Kidney Dis 44:729-37. 2004
    Encapsulating peritoneal sclerosis (EPS) is recognized as a rare but serious complication of peritoneal dialysis (PD). The aim of this study was to determine the incidence, clinical features, and mortality rate of EPS.
  86. ncbi Can a reduction in extracellular fluid volume result in increased serum albumin in peritoneal dialysis patients?
    Colin H Jones
    Department of Renal Medicine, York District Hospital, York, United Kingdom
    Am J Kidney Dis 39:872-5. 2002
    ..We investigated whether decreasing dry weight increases serum albumin in peritoneal dialysis patients...
  87. doi Biocompatibility of a bicarbonate-buffered amino-acid-based solution for peritoneal dialysis
    Thorsten O Bender
    Department of Nephrology and Medical Intensive Care, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Pediatr Nephrol 23:1537-43. 2008
    Amino-acid-based peritoneal dialysis (PD) fluids have been developed to improve the nutritional status of PD patients...
  88. ncbi Fatigue in chronic peritoneal dialysis patients
    Shahrzad Ossareh
    Peritoneal Dialysis Program, Toronto Western Hospital, Division of Nephrology, University of Toronto, Canada
    Int Urol Nephrol 35:535-41. 2003
    ..Anemia seems to be the most important factor associated with fatigue. Dialysis adequacy and nutritional state did not show any correlation with the frequency of fatigue in our study...
  89. ncbi Use of ACE inhibitors or angiotensin receptor blockers and survival in patients on peritoneal dialysis
    Wei Fang
    University Health Network, University of Toronto, Toronto, Ontario, Canada
    Nephrol Dial Transplant 23:3704-10. 2008
    ..However, their effect on survival has not been studied in peritoneal dialysis (PD) patients...
  90. ncbi Efficacy of intravenous methoxy polyethylene glycol-epoetin beta administered every 2 weeks compared with epoetin administered 3 times weekly in patients treated by hemodialysis or peritoneal dialysis: a randomized trial
    Marian Klinger
    Department of Nephrology and Transplantation Medicine, Medical University, Wroclaw, Poland
    Am J Kidney Dis 50:989-1000. 2007
    ..We examined its efficacy for Hb level correction when administered once every 2 weeks in erythropoiesis-stimulating agent-naive dialysis patients...
  91. doi Factors associated with blood concentrations of indoxyl sulfate and p-cresol in patients undergoing peritoneal dialysis
    Chien Te Lee
    Division of Nephrology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
    Perit Dial Int 30:456-63. 2010
    ..Factors relevant to indoxyl sulfate and p-cresol levels in peritoneal dialysis (PD) patients have rarely been investigated...
  92. ncbi The efficacy of silver-ion implanted catheters in reducing peritoneal dialysis-related infections
    John H Crabtree
    Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, Bellflower, California 90706, USA
    Perit Dial Int 23:368-74. 2003
    ..Dialysis-related infections are the commonest cause of catheter loss and transfer to hemodialysis. Surface modifications of the catheter that reduce infections are of major importance...
  93. ncbi Induction of mesothelial HSP-72 upon in vivo exposure to peritoneal dialysis fluid
    Klaus Arbeiter
    Vienna School of Medicine
    Perit Dial Int 23:499-501. 2003
  94. pmc Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active
    Takashi Shimada
    Endocrine Unit, Thier 10, 50 Blossum Street, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 95:578-85. 2010
    ....
  95. doi Epidemiology of peritoneal dialysis: a story of believers and nonbelievers
    Norbert Lameire
    Renal Division, University Hospital, 185 De Pintelaan, 9000 Gent, Belgium
    Nat Rev Nephrol 6:75-82. 2010
    ..In this Review, we compare the epidemiology of peritoneal dialysis with that of hemodialysis and describe some of the major differences in the global utilization of the two ..
  96. ncbi Analysis of depression and its effect on outcome among adult Indian peritoneal dialysis patients
    Sandeep Mahajan
    Department of Nephrology, All India Institute of Medical Sciences, Delhi, India
    Perit Dial Int 27:94-6. 2007
  97. ncbi Biocompatible peritoneal dialysis solutions: do we have one?
    Kunal Chaudhary
    Division of Nephrology and Hypertension, University of Missouri Columbia School of Medicine, Harry S Truman VA Medical Center, 800 Hospital Drive, Columbia, MO 65201, USA
    Clin J Am Soc Nephrol 5:723-32. 2010
    Clinical experience and literature evidence suggest that peritoneal dialysis (PD) is a safe and effective treatment in short term (3 to 5 years) for stage 5 chronic kidney disease patients...
  98. doi Does diabetes mellitus predispose to increased fluid overload in peritoneal dialysis patients?
    Andrew Davenport
    University College London Center for Nephrology, Royal Free and University College Medical School, London, UK
    Nephron Clin Pract 114:c60-6. 2010
    Diabetic peritoneal dialysis patients have been reported to have faster peritoneal solute transport and may be at risk of reduced ultrafiltration volumes, leading to fluid overload.
  99. ncbi The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in Japan
    Ichiro Hirahara
    Division of Nephrology, Department of Medicine, Jichi Medical School, 3311 1 Yakushiji, Shimotsuke City, Tochigi 329 0498, Japan
    Nephrol Dial Transplant 22:560-7. 2007
    Long-term peritoneal dialysis (PD) leads to peritoneal injury. At worst, peritoneal injury leads to encapsulating peritoneal sclerosis (EPS), which is a serious complication of PD. The mortality rate of EPS is extremely high...
  100. ncbi Change in bacterial aetiology of peritoneal dialysis-related peritonitis over 10 years: experience from a centre in South-East Asia
    C C Szeto
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Clin Microbiol Infect 11:837-9. 2005
    This study reviewed 1787 episodes of peritoneal dialysis (PD)-related peritonitis in 544 patients between 1994 and 2003. The overall rate of peritonitis was 0.68 episodes/year of PD, but decreased from 1.10 to 0...
  101. ncbi Reduction of perlecan synthesis and induction of TGF-beta1 in human peritoneal mesothelial cells due to high dialysate glucose concentration: implication in peritoneal dialysis
    Susan Yung
    Division of Nephrology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
    J Am Soc Nephrol 15:1178-88. 2004
    ..its selective permeability, thereby impairing the peritoneal transport properties in patients on long-term peritoneal dialysis (PD)...

Research Grants85

  1. An all titanium transcutaneous access device (TAD) for peritoneal dialysis
    Robert Whalen; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Chronic transcutaneous access is needed for peritoneal dialysis (PD) and new emerging medical therapies...
  2. Conservative Versus Dialytic Management in Stage V Chronic Kidney Disease
    GLENN MATTHEW CHERTOW; Fiscal Year: 2010
    ..73m2. The dialytic intervention will include initiation of thrice weekly hemodialysis or conventional peritoneal dialysis following randomization...
  3. Conservative Versus Dialytic Management in Stage V Chronic Kidney Disease
    Glenn Chertow; Fiscal Year: 2009
    ..73m2. The dialytic intervention will include initiation of thrice weekly hemodialysis or conventional peritoneal dialysis following randomization...
  4. Metabolic Bone Diseases and Renal Osteodystrophy
    Jinghua Wang; Fiscal Year: 2003
    ..Patients undergoing continuous ambulatory peritoneal dialysis are likely to have nearly constant serum level of collagen degradation products, while the daily burden of ..
  5. Bone turnover in dialysis patients
    Jinghua Wang; Fiscal Year: 2003
    ..Patients undergoing continuous ambulatory peritoneal dialysis are likely to have nearly constant serum level of collagen degradation products, while the daily burden of ..
  6. COATING OF URINARY PROTHESES TO PREVENT ENCRUSTATION
    Harmeet Sidhu; Fiscal Year: 2000
    ..catheters are frequently used in urological and nephrological medicine for the management of urinary and peritoneal dialysis flow, haemodialysis, and drainage of renal calculi following laser or lithotripsy treatment...
  7. AMBULATORY PERITONEAL DIALYSIS--PHARMACOKINETICS OF LAMIVUDINE IN HIV
    Paul Bohjanen; Fiscal Year: 1999
    ..number of HIV- infected patients also have severe renal failure and are undergoing continuous ambulatory peritoneal dialysis (CAPD). The effect of CAPD on elimination of lamivudine is currently unknown...
  8. AMBULATORY PERITONEAL DIALYSIS--PHARMACOKINETICS OF LAMIVUDINE IN HIV
    Paul Bohjanen; Fiscal Year: 2000
    ..number of HIV- infected patients also have severe renal failure and are undergoing continuous ambulatory peritoneal dialysis (CAPD). The effect of CAPD on elimination of lamivudine is currently unknown...
  9. AMBULATORY PERITONEAL DIALYSIS--PHARMACOKINETICS OF LAMIVUDINE IN HIV
    Paul Bohjanen; Fiscal Year: 2001
    ..number of HIV- infected patients also have severe renal failure and are undergoing continuous ambulatory peritoneal dialysis (CAPD). The effect of CAPD on elimination of lamivudine is currently unknown...
  10. REGULATION OF BONE FORMATION IN RENAL OSTEODYSTROPHY
    ISIDRO SALUSKY; Fiscal Year: 2002
    ..on bone formation and parathyroid gland function in children with bone biopsy proven 2-HPT and treated with peritoneal dialysis. Also the response to these two vitamin D sterols will be assessed in patients given calcium carbonate or a ..
  11. REGULATION OF BONE FORMATION IN RENAL OSTEODYSTROPHY
    ISIDRO SALUSKY; Fiscal Year: 2003
    ..on bone formation and parathyroid gland function in children with bone biopsy proven 2-HPT and treated with peritoneal dialysis. Also the response to these two vitamin D sterols will be assessed in patients given calcium carbonate or a ..
  12. REGULATION OF BONE FORMATION IN RENAL OSTEODYSTROPHY
    ISIDRO SALUSKY; Fiscal Year: 2000
    ..on bone formation and parathyroid gland function in children with bone biopsy proven 2-HPT and treated with peritoneal dialysis. Also the response to these two vitamin D sterols will be assessed in patients given calcium carbonate or a ..
  13. REGULATION OF BONE FORMATION IN RENAL OSTEODYSTROPHY
    Isidro B Salusky; Fiscal Year: 2004
    ..on bone formation and parathyroid gland function in children with bone biopsy proven 2-HPT and treated with peritoneal dialysis. Also the response to these two vitamin D sterols will be assessed in patients given calcium carbonate or a ..
  14. REGULATION OF BONE FORMATION IN RENAL OSTEODYSTROPHY
    ISIDRO SALUSKY; Fiscal Year: 2001
    ..on bone formation and parathyroid gland function in children with bone biopsy proven 2-HPT and treated with peritoneal dialysis. Also the response to these two vitamin D sterols will be assessed in patients given calcium carbonate or a ..
  15. Effects of Hyaluronan on Interstitial Convection
    MICHAEL FLESSNER; Fiscal Year: 2004
    ..to quantify solute diffusion and convection in the subperitoneal muscle of anesthetized rats during peritoneal dialysis. The in vivo model permits control of the tissue pressure forces and measurement of the pressure profile ..
  16. Effects of Hyaluronan on Interstitial Convection
    MICHAEL FLESSNER; Fiscal Year: 2007
    ..to quantify solute diffusion and convection in the subperitoneal muscle of anesthetized rats during peritoneal dialysis. The in vivo model permits control of the tissue pressure forces and measurement of the pressure profile ..
  17. Effects of Hyaluronan on Interstitial Convection
    MICHAEL FLESSNER; Fiscal Year: 2006
    ..to quantify solute diffusion and convection in the subperitoneal muscle of anesthetized rats during peritoneal dialysis. The in vivo model permits control of the tissue pressure forces and measurement of the pressure profile ..
  18. Effects of Hyaluronan on Interstitial Convection
    MICHAEL FLESSNER; Fiscal Year: 2005
    ..to quantify solute diffusion and convection in the subperitoneal muscle of anesthetized rats during peritoneal dialysis. The in vivo model permits control of the tissue pressure forces and measurement of the pressure profile ..
  19. Effects of Hyaluronan on Interstitial Convection
    MICHAEL FLESSNER; Fiscal Year: 2003
    ..to quantify solute diffusion and convection in the subperitoneal muscle of anesthetized rats during peritoneal dialysis. The in vivo model permits control of the tissue pressure forces and measurement of the pressure profile ..
  20. Dynamics of Peritoneal Dialysis Associated Peritonitis
    John Hotchkiss; Fiscal Year: 2004
    ..on interactions between dynamics of bacterial growth and optimal bacterial clearance in the setting of peritoneal dialysis associated peritonitis (PDAP)...
  21. Dynamics of Peritoneal Dialysis Associated Peritonitis
    John Hotchkiss; Fiscal Year: 2003
    ..on interactions between dynamics of bacterial growth and optimal bacterial clearance in the setting of peritoneal dialysis associated peritonitis (PDAP)...
  22. Stent Lock Mechanism for Transcutaneous Catheters
    NICHOLAS VITALE; Fiscal Year: 2005
    b>Peritoneal dialysis, intravascular access for chemotherapy, transcutaneous intrathoracic access of cardiac power lines, and suprapubic bladder drainage are among the clinical applications where transcutaneous catheters are routinely used ..
  23. FUNCTIONAL ANALYSIS OF VASCULAR ANGIOTENSIN II
    BEN ZIMMERMAN; Fiscal Year: 1990
    ..balance and plasma urea and to further induce the influence of vasculature AII, the animals will undergo peritoneal dialysis before each experiment at 1, 2 and 4 days post op...
  24. Associations among RAAS Inhibitors, Residual Kidney Function, and CV Events in PD
    Jenny I Shen; Fiscal Year: 2012
    ..However, data on their effectiveness in patients undergoing peritoneal dialysis (PD) are limited...
  25. GENERAL CLINICAL RESEARCH CENTER
    CECIL SAMUELSON; Fiscal Year: 1990
    ..studies in leukemia and malignant diseases in children, improved techniques for hemodialysis and peritoneal dialysis, the genetic transmission of a number of diseases including hemochromatosis, prostatic cancer, coronary ..
  26. IN VIVO STUDY OF INTERSTITIAL CONVECTION
    MICHAEL FLESSNER; Fiscal Year: 1999
    ..homeostasis but also of major importance in therapeutic procedures such as macromolecular drug delivery or peritoneal dialysis. Recently proposed mathematical models of interstitial fluid and protein transport include theories of ..
  27. CALCITRIOL THERAPY ON DIALYZED CHILDREN
    ISIDRO SALUSKY; Fiscal Year: 1993
    ..calcitriol will be performed in pediatric patients with secondary hyperparathyroidism and treated with peritoneal dialysis. Therapeutic responses will be judged by changes in biochemical indices of parathyroid hormone secretion ..
  28. CALCITRIOL THERAPY ON DIALYZED CHILDREN
    ISIDRO SALUSKY; Fiscal Year: 1990
    ..calcitriol will be performed in pediatric patients with secondary hyperparathyroidism and treated with peritoneal dialysis. Therapeutic responses will be judged by changes in biochemical indices of parathyroid hormone secretion ..
  29. CALCITRIOL THERAPY ON DIALYZED CHILDREN
    ISIDRO SALUSKY; Fiscal Year: 1991
    ..calcitriol will be performed in pediatric patients with secondary hyperparathyroidism and treated with peritoneal dialysis. Therapeutic responses will be judged by changes in biochemical indices of parathyroid hormone secretion ..
  30. CALCITRIOL THERAPY ON DIALYZED CHILDREN
    ISIDRO SALUSKY; Fiscal Year: 1992
    ..calcitriol will be performed in pediatric patients with secondary hyperparathyroidism and treated with peritoneal dialysis. Therapeutic responses will be judged by changes in biochemical indices of parathyroid hormone secretion ..
  31. MUSCULOSKELETAL DISORDERS IN DIALYSIS PATIENTS
    Sharon Moe; Fiscal Year: 2003
    ..is a cross-over study evaluating the effect of a new phosphate binder, sevelamer, on calcium balance in peritoneal dialysis patients...
  32. MUSCULOSKELETAL DISORDERS IN DIALYSIS PATIENTS
    Sharon Moe; Fiscal Year: 2000
    ..is a cross-over study evaluating the effect of a new phosphate binder, sevelamer, on calcium balance in peritoneal dialysis patients...
  33. ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASE
    Alan Christensen; Fiscal Year: 2003
    ..g., continuous ambulatory peritoneal dialysis) but poorer adherence when receiving staff administered dialysis (e.g., center hemodialysis)...
  34. MUSCULOSKELETAL DISORDERS IN DIALYSIS PATIENTS
    Sharon Moe; Fiscal Year: 2002
    ..is a cross-over study evaluating the effect of a new phosphate binder, sevelamer, on calcium balance in peritoneal dialysis patients...
  35. ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASE
    Alan Christensen; Fiscal Year: 2000
    ..g., continuous ambulatory peritoneal dialysis) but poorer adherence when receiving staff administered dialysis (e.g., center hemodialysis)...
  36. MUSCULOSKELETAL DISORDERS IN DIALYSIS PATIENTS
    Sharon Moe; Fiscal Year: 2004
    ..is a cross-over study evaluating the effect of a new phosphate binder, sevelamer, on calcium balance in peritoneal dialysis patients...
  37. ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASE
    Alan Christensen; Fiscal Year: 2003
    ..g., continuous ambulatory peritoneal dialysis) but poorer adherence when receiving staff administered dialysis (e.g., center hemodialysis)...
  38. ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASE
    Alan Christensen; Fiscal Year: 2002
    ..g., continuous ambulatory peritoneal dialysis) but poorer adherence when receiving staff administered dialysis (e.g., center hemodialysis)...
  39. ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASE
    Alan Christensen; Fiscal Year: 2001
    ..g., continuous ambulatory peritoneal dialysis) but poorer adherence when receiving staff administered dialysis (e.g., center hemodialysis)...
  40. MUSCULOSKELETAL DISORDERS IN DIALYSIS PATIENTS
    Sharon Moe; Fiscal Year: 2001
    ..is a cross-over study evaluating the effect of a new phosphate binder, sevelamer, on calcium balance in peritoneal dialysis patients...
  41. Assessing Functional Outcomes in Adolescent with ESRD
    Susan Furth; Fiscal Year: 2001
    ..quality of life (HRQL) for pediatric patients with chronic renal failure or ESRD treated with hemodialysis, peritoneal dialysis or transplant. Resources provided by the RO3 award will allow Dr...
  42. GENERAL CLINICAL RESEARCH CENTER
    LAYTON MCCURDY; Fiscal Year: 1993
    ..artery angioplasty; pathogenesis of the Williams syndrome; albumin metabolism in patients on chronic peritoneal dialysis; treatment of scleroderma by photopheresis and of scleroderma renal disease with inhibitors of angiotensin-..
  43. Assessing Functional Outcomes in Adolescent with ESRD
    Susan Furth; Fiscal Year: 2002
    ..quality of life (HRQL) for pediatric patients with chronic renal failure or ESRD treated with hemodialysis, peritoneal dialysis or transplant. Resources provided by the RO3 award will allow Dr...
  44. The Production of Uremic Solutes by Colon Microbes
    Timothy Meyer; Fiscal Year: 2009
    ..investigators have identified large differences in indican and p-cresol sulfate production in patients on peritoneal dialysis and patients on hemodialysis...
  45. Commercialization of Human Omental Mesothelial Cells for Research
    YOLANDA LEA CURRIE; Fiscal Year: 2007
    ..DESCRIPTION (provided by applicant): Mesothelial cells have been found to be pivotal in tumor metastasis, peritoneal dialysis, and inflammatory response...
  46. The Production of Uremic Solutes by Colon Microbes
    Timothy W Meyer; Fiscal Year: 2010
    ..investigators have identified large differences in indican and p-cresol sulfate production in patients on peritoneal dialysis and patients on hemodialysis...
  47. PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULES
    MICHAEL FLESSNER; Fiscal Year: 2004
    ..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
  48. PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULES
    MICHAEL FLESSNER; Fiscal Year: 2001
    ..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
  49. PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULES
    MICHAEL FLESSNER; Fiscal Year: 2003
    ..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
  50. PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULES
    MICHAEL FLESSNER; Fiscal Year: 2001
    ..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
  51. PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULES
    MICHAEL FLESSNER; Fiscal Year: 2002
    ..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
  52. PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULES
    MICHAEL FLESSNER; Fiscal Year: 2000
    ..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
  53. S.T.R.A.P Sonos Transportable Renal Application Product
    Martin Roberts; Fiscal Year: 2005
    ..5 billion. Hemodialysis requires patient treatment 3 times a week for 3-4 hours. Peritoneal dialysis is an option utilized by less than 10% of patients requiring manual exchange of 2 liters of dialysate every ..
  54. Commercialization of Human Mesothelial Cells for Research
    YOLANDA LEA CURRIE; Fiscal Year: 2009
    Mesothelial cells have been found to be pivotal in tumor metastasis, peritoneal dialysis, and inflammatory response...
  55. Commercialization of Human Mesothelial Cells for Research
    YOLANDA RENEE LEA CURRIE; Fiscal Year: 2010
    Mesothelial cells have been found to be pivotal in tumor metastasis, peritoneal dialysis, and inflammatory response...
  56. DIURNAL AND PULSATILE PTH SECRETION IN RENAL FAILURE
    William Goodman; Fiscal Year: 2001
    ..with secondary hyperparathyroidism will also be evaluated, and the respective roles of hemodialysis and peritoneal dialysis as separate modifiers of diurnal and pulsatile PTH secretion in end-stage renal disease will be examined...
  57. DIURNAL AND PULSATILE PTH SECRETION IN RENAL FAILURE
    William Goodman; Fiscal Year: 1999
    ..with secondary hyperparathyroidism will also be evaluated, and the respective roles of hemodialysis and peritoneal dialysis as separate modifiers of diurnal and pulsatile PTH secretion in end-stage renal disease will be examined...
  58. DIURNAL AND PULSATILE PTH SECRETION IN RENAL FAILURE
    William Goodman; Fiscal Year: 2000
    ..with secondary hyperparathyroidism will also be evaluated, and the respective roles of hemodialysis and peritoneal dialysis as separate modifiers of diurnal and pulsatile PTH secretion in end-stage renal disease will be examined...
  59. Acute Renal Failure Mediated Lung Injury
    Sarah Faubel; Fiscal Year: 2010
    ..if the uremic factors that stimulate IL-6 production in AKI may be removed by dialysis, the effect of acute peritoneal dialysis on IL-6 production and serum IL-6 will be determined...
  60. CALCIMIMETIC AGENT IN RENAL DISEASE HYPERPARATHYROIDISM
    Sharon Moe; Fiscal Year: 2000
    Patients with end-stage renal disease (ESRD), including those patients already on either hemo- or peritoneal dialysis, have a multitude of metabolic abnormalities secondary to the diseased and nonfunctioning kidney...
  61. Acute Renal Failure Mediated Lung Injury
    Sarah Faubel; Fiscal Year: 2009
    ..if the uremic factors that stimulate IL-6 production in AKI may be removed by dialysis, the effect of acute peritoneal dialysis on IL-6 production and serum IL-6 will be determined...
  62. AMBULATORY PERITONEAL DIALYSIS--PHARMACOKINETICS OF LAMIVUDINE IN HIV
    Paul Bohjanen; Fiscal Year: 2000
    ..number of HIV-infected patients also have severe renal failure and are undergoing continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis...
  63. Comorbidity, Costs and Outcomes in Dialysis Patients
    Srinivasan Beddhu; Fiscal Year: 2001
    ..Prior studies showed patients with high comorbidity have higher peritoneal dialysis technique failure...
  64. Comorbidity, Costs and Outcomes in Dialysis Patients
    Srinivasan Beddhu; Fiscal Year: 2002
    ..Prior studies showed patients with high comorbidity have higher peritoneal dialysis technique failure...
  65. MALNUTRITION IN DIALYSIS PATIENTS
    Raymond Hakim; Fiscal Year: 1992
    ..Finally, we propose to explore the effects of rhGH on the nutritional parameters of peritoneal dialysis patients...
  66. PRODUCTION OF STERILE WATER FOR INJECTION ON DEMAND
    Edit Hegyi; Fiscal Year: 2001
    ..of sterile online mixing technology it will provide sterile replacement fluids and sterile dialyzate for peritoneal dialysis and continuous renal replacement therapy...
  67. Understanding Sources of Bias and Outcomes in Peritoneal Dialysis Patient Researc
    Kamyar Kalantar Zadeh; Fiscal Year: 2009
    ..by applicant): The proportion of individuals with advanced chronic kidney disease who undergo chronic peritoneal dialysis (CPD) treatment, currently <8% of the 400,000 dialysis patients in the USA, has been declining steadily ..
  68. PROSPECTIVE STUDY OF DIALYSIS OUTCOME--ROLE OF CYTOKINES
    MIRIAM WEISS; Fiscal Year: 1992
    ..The high morbidity and mortality of both hemodialysis (HD) and peritoneal dialysis (PD) cannot be fully explained by adequacy of dialysis (KT/V) and protein catabolic rate...
  69. Understanding Sources of Bias and Outcomes in Peritoneal Dialysis Patient Researc
    Kamyar Kalantar Zadeh; Fiscal Year: 2010
    ..by applicant): The proportion of individuals with advanced chronic kidney disease who undergo chronic peritoneal dialysis (CPD) treatment, currently <8% of the 400,000 dialysis patients in the USA, has been declining steadily ..
  70. Dietary Adherence Enhancement in Peritoneal Dialysis
    MARY SEVICK; Fiscal Year: 2007
    ..study will pilot test an intervention! based on self-efficacy theory, to improve adherence to the peritoneal dialysis dietary regimen...
  71. Dietary Adherence Enhancement in Peritoneal Dialysis
    MARY SEVICK; Fiscal Year: 2006
    ..study will pilot test an intervention! based on self-efficacy theory, to improve adherence to the peritoneal dialysis dietary regimen...
  72. Patient-Oriented Research in Kidney Disease
    Neil Powe; Fiscal Year: 2007
    ..This is a national prospective cohort study comparing treatment and outcomes in hemodialysis and peritoneal dialysis patients...
  73. PATIENT ADHERENCE AND ADJUSTMENT IN RENAL DIALYSIS
    Alan Christensen; Fiscal Year: 1999
    ..e., continuous ambulatory peritoneal dialysis-- CAPD) but poorer adherence when receiving staff-administered dialysis (i.e., center hemodialysis)...
  74. Patient-Oriented Research in Kidney Disease
    Neil R Powe; Fiscal Year: 2009
    ..This is a national prospective cohort study comparing treatment and outcomes in hemodialysis and peritoneal dialysis patients...
  75. LONG-TERM PERCUTANEOUS ACCESS DEVICE FOR HOME THERAPIES
    Paul Freed; Fiscal Year: 1999
    ..that require long- term body access, such as total parenteral nutrition, drug delivery, ambulatory peritoneal dialysis, and heart assist devices...
  76. Patient-Oriented Research in Kidney Disease
    Neil Powe; Fiscal Year: 2009
    ..This is a national prospective cohort study comparing treatment and outcomes in hemodialysis and peritoneal dialysis patients...
  77. Patient-Oriented Research in Kidney Disease
    Neil Powe; Fiscal Year: 2006
    ..This is a national prospective cohort study comparing treatment and outcomes in hemodialysis and peritoneal dialysis patients...
  78. LONG-TERM PERCUTANEOUS ACCESS DEVICE FOR HOME THERAPIES
    ROGER SNYDER; Fiscal Year: 2004
    ..devices for treatment of chronic heart failure, total parenteral nutrition, drug delivery, and ambulatory peritoneal dialysis. The PAD is pre-seeded with autologous fibroblasts derived from a small sample of the recipient's skin...
  79. LONG-TERM PERCUTANEOUS ACCESS DEVICE FOR HOME THERAPIES
    LUDMILA BERNSTAM; Fiscal Year: 2005
    ..devices for treatment of chronic heart failure, total parenteral nutrition, drug delivery, and ambulatory peritoneal dialysis. The PAD is pre-seeded with autologous fibroblasts derived from a small sample of the recipient's skin...
  80. Patient-Oriented Research in Kidney Disease
    Neil Powe; Fiscal Year: 2005
    ..This is a national prospective cohort study comparing treatment and outcomes in hemodialysis and peritoneal dialysis patients...
  81. PATIENT ORIENTED RESEARCH IN KIDNEY DISEASE
    Neil Powe; Fiscal Year: 1999
    ..This is a national prospective cohort study comparing peritoneal dialysis and hemodialysis and a large versus small dose of dialysis...
  82. PATIENT ORIENTED RESEARCH IN KIDNEY DISEASE
    Neil Powe; Fiscal Year: 2002
    ..This is a national prospective cohort study comparing peritoneal dialysis and hemodialysis and a large versus small dose of dialysis...
  83. ASSESSING PATIENT OUTCOMES IN PEDIATRIC ESRD
    Susan Furth; Fiscal Year: 2002
    ..S. Renal Data System. We propose to identify how treatment with hemodialysis, peritoneal dialysis or transplantation and the facility's experience with children independently affect clinical outcomes...