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| peritoneal dialysisSummarySummary: Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure. Top Publications
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Publications
Morphologic changes in the peritoneal membrane of patients with renal diseaseJohn D Williams
Institute of Nephrology, University of Wales College of Medicine, Cardiff, United Kingdom
J Am Soc Nephrol 13:470-9. 2002This study examined the morphologic features of the parietal peritoneal membranes of 130 patients undergoing peritoneal dialysis (PD) and compared them with the features of the peritoneal membranes of normal individuals, uremic ..
Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventionsLuiz S Aroeira
Unidad de Biologia Molecular, Hospital Universitario de la Princesa, C Diego de Leon 62, Madrid, Spain
J Am Soc Nephrol 18:2004-13. 2007b>Peritoneal dialysis (PD) is a form of renal replacement and is based on the use of the peritoneum as a semipermeable membrane across which ultrafiltration and diffusion take place...
The pathophysiology of the peritoneal membraneOlivier Devuyst
Division of Nephrology, UCL Medical School, 10 Avenue Hippocrate, B 1200 Brussels, Belgium
J Am Soc Nephrol 21:1077-85. 2010The development of peritoneal dialysis (PD) as a successful therapy has and still depends on experimental models to test and understand critical pieces of pathophysiology...
Similar outcomes with hemodialysis and peritoneal dialysis in patients with end-stage renal diseaseRajnish Mehrotra
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
Arch Intern Med 171:110-8. 2011The annual payer costs for patients treated with peritoneal dialysis (PD) are lower than with hemodialysis (HD), but in 2007, only 7% of dialysis patients in the United States were treated with PD...
Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patientsEric D Weinhandl
Chronic Disease Research Group, Minneapolis, MN 55404, USA
J Am Soc Nephrol 21:499-506. 2010Contemporary comparisons of mortality in matched hemodialysis and peritoneal dialysis patients are lacking...
Peritoneal glucose exposure and changes in membrane solute transport with time on peritoneal dialysisS J Davies
Department of Nephrology, North Staffordshire Hospitals Trust, Stoke on Trent, United Kingdom
J Am Soc Nephrol 12:1046-51. 2001Peritoneal solute transport increases with time on treatment in a proportion of peritoneal dialysis (PD) patients, contributing to ultrafiltration failure...
Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysisGareth W Roberts
Institute of Nephrology, School of Medicine, Cardiff University, Heath Park, Cardiff, Wales, UK
J Am Soc Nephrol 20:1895-900. 2009..peritonitis adversely affect the structure and function of the peritoneal membrane in patients treated with peritoneal dialysis (PD), but the underlying mechanisms are not well understood...
Body composition, hydration, and related parameters in hemodialysis versus peritoneal dialysis patientsIsabel Devolder
Renal Division, University Hospital Ghent, Ghent, Belgium
Perit Dial Int 30:208-14. 2010..A new multifrequency bioimpedance tool has recently been validated. This study compares volume status in peritoneal dialysis (PD) and hemodialysis (HD) patients in a single center.
The influence of dialysate calcium on progression of arterial stiffness in peritoneal dialysis patientsMeltem Sezis Demirci
Division of Nephrology, Ege University School of Medicine, Izmir, Turkey
Perit Dial Int 29:S15-7. 2009One of the origins of cardiovascular disease in dialysis patients is arterial stiffness. The aim of our study was to assess the relationship between the calcium content of peritoneal dialysis (PD) solution and arterial stiffness.
Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in VietnamNguyen Hoan Phu
Center for Tropical Diseases, Center for Tropical Diseases, Cho Quan Hospital, Ho Chi Minh City, Vietnam
N Engl J Med 347:895-902. 2002BACKGROUND: In some parts of the world, peritoneal dialysis is widely used for renal replacement in acute renal failure...
Peritonitis remains the major clinical complication of peritoneal dialysis: the London, UK, peritonitis audit 2002-2003Andrew Davenport
UCL Centre for Nephrology, Royal Free and University College Medical School, London, United Kingdom
Perit Dial Int 29:297-302. 2009Over the past two decades, the rate of peritonitis in patients treated by peritoneal dialysis (PD) has been significantly reduced...
Predictors of loss of residual renal function among new dialysis patientsL M Moist
Department of Medicine, University of Western Ontario, London, Canada
J Am Soc Nephrol 11:556-64. 2000..to determine the predictors of RRF loss in a national random sample of patients initiating hemodialysis and peritoneal dialysis. The study controlled for baseline variables and included major predictors...
Peritoneal changes after exposure to sterile solutions by catheterMichael F Flessner
Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
J Am Soc Nephrol 18:2294-302. 2007..These findings confirm the hypothesis that the presence of a PC catheter increases inflammatory response to sterile solutions as evidenced by the structural and functional changes in the peritoneal barrier...
Mesothelial cellsSusan Yung
Department of Medicine, University of Hong Kong, Hong Kong SAR, PR China
Perit Dial Int 27:S110-5. 2007The introduction of peritoneal dialysis (PD) as a modality of renal replacement therapy has provoked much interest in the biology of the peritoneal mesothelial cell...
Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cellsSonja Mandl-Weber
Nephrologisches Zentrum, Medizinische Klinik und Poliklinik-Innenstadt, , Munich, Germany
Kidney Int 61:570-8. 2002BACKGROUND: Vascular endothelial growth factor (VEGF) was recently found in peritoneal effluents of peritoneal dialysis (PD) patients...
The effects of renin-angiotensin system inhibition on regression of encapsulating peritoneal sclerosisDevrim Bozkurt
Department of Nephrology, Ege University, Izmir, Turkey
Perit Dial Int 28:S38-42. 2008..b>Peritoneal dialysis (PD) patients rarely develop EPS, a severe life-threatening condition of unknown pathogenesis...
The role of the TGF/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutionsQiang Yao
Divisions of Baxter Novum and Renal Medicine, Department of Clinical Science, Karolinska Institutet, Stockholm, Sweden
Nephron Exp Nephrol 109:e71-8. 2008b>Peritoneal dialysis (PD) solutions contribute to peritoneal membrane damage...
Cost comparison of peritoneal dialysis versus hemodialysis in end-stage renal diseaseAriel Berger
Policy Analysis, Inc, Four Davis Ct, Brookline, MA 02445, USA
Am J Manag Care 15:509-18. 2009To compare healthcare utilization and costs in patients with end-stage renal disease (ESRD) beginning peritoneal dialysis (PD) or hemodialysis (HD).
Severe vitamin D deficiency in chronic renal failure patients on peritoneal dialysisH Taskapan
Inonu University Medical School, Department of Medicine, Division of Nephrology, Malatya, Turkey
Clin Nephrol 66:247-55. 2006The aim of this study was to evaluate the prevalence of vitamin D deficiency in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with various demographic and renal osteodystrophy markers.
Serum matrix metalloproteinases MMP-2 and MMP-3 levels in dialysis patients vary independently of CRP and IL-6 levelsGloria A Preston
Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Nephron 92:817-23. 2002Patients on chronic hemodialysis or peritoneal dialysis often develop an inflammatory state that causes morbidity and mortality...
Impact of ACE inhibitors and AII receptor blockers on peritoneal membrane transport characteristics in long-term peritoneal dialysis patientsInna Kolesnyk
Division of Nephrology, Academic Medical Center, Amsterdam, The Netherlands
Perit Dial Int 27:446-53. 2007Long-term peritoneal dialysis (PD) may lead to peritoneal fibrosis and ultrafiltration failure. The latter occurs due to high solute transport rates and diabetiform peritoneal sclerosis...
Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysisJ Ni
Division of Nephrology and Department of Pathology, UCL Medical School, Brussels, Belgium
Kidney Int 69:1518-25. 2006..of the implication of AQP1 in solute-free water transport, sodium sieving, and ultrafiltration (UF) during peritoneal dialysis (PD) is lacking, and the effects of its deletion on the structure of the membrane are unknown...
Increases in serum leptin levels during peritoneal dialysis are associated with inflammation and a decrease in lean body massP Stenvinkel
Division of Renal Medicine, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
J Am Soc Nephrol 11:1303-9. 2000..elevated leptin levels have been documented in uremic patients, especially in those who are treated by peritoneal dialysis (PD)...
Sodium removal in patients undergoing CAPD and automated peritoneal dialysisAna Rodriguez-Carmona
Division of Nephrology, Hospital Juan Canalejo, A Coruna, Spain
Perit Dial Int 22:705-13. 2002To compare sodium removal in continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) patients, and to identify the main factors that modify Na removal in clinical practice in these patients.
Continuous peritoneal dialysis-associated peritonitis: a review and current conceptsLaura Troidle
New Haven CAPD, Renal Research Institute, New Haven, Connecticut, USA
Semin Dial 16:428-37. 2003The percentage of end-stage renal disease (ESRD) patients in the United States maintained on continuous peritoneal dialysis (CPD) therapy is decreasing...
The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membraneJohn D Williams
Institute of Nephrology, University Hospital of Wales College of Medicine, Heath Park, Cardiff, Wales, UK
Kidney Int 66:408-18. 2004Although peritoneal dialysis (PD) is a widely accepted form of renal replacement therapy (RRT), concerns remain regarding the bioincompatible nature of standard PD fluid...
Mortality and technique failure in patients starting chronic peritoneal dialysis: results of The Netherlands Cooperative Study on the Adequacy of Dialysis. NECOSAD Study GroupK J Jager
Department of Nephrology, Academic Medical Center, University of Amsterdam, The Netherlands
Kidney Int 55:1476-85. 1999..The aim of this study was to determine the relative importance of baseline patient and treatment characteristics to mortality and technique failure in patients starting peritoneal dialysis.
The differential impact of risk factors on mortality in hemodialysis and peritoneal dialysisEdward F Vonesh
Baxter Healthcare Corporation, Applied Statistics Center, Round Lake, Illinois 60073, USA
Kidney Int 66:2389-401. 2004..Trends in available data indicate the relative risk of death with hemodialysis (HD) compared to peritoneal dialysis (PD) varies by time on dialysis and the presence of various risk factors...
Icodextrin improves the fluid status of peritoneal dialysis patients: results of a double-blind randomized controlled trialSimon J Davies
University Hospital of North Staffordshire, Stoke on Trent, England
J Am Soc Nephrol 14:2338-44. 2003Worsening fluid balance results in reduced technique and patient survival in peritoneal dialysis. Under these conditions, the glucose polymer icodextrin is known to enhance ultrafiltration in the long dwell...
Induction of mesothelial HSP-72 upon in vivo exposure to peritoneal dialysis fluidKlaus Arbeiter
Vienna School of Medicine
Perit Dial Int 23:499-501. 2003
Use of ACE inhibitors or angiotensin receptor blockers and survival in patients on peritoneal dialysisWei Fang
University Health Network, University of Toronto, Toronto, Ontario, Canada
Nephrol Dial Transplant 23:3704-10. 2008..However, their effect on survival has not been studied in peritoneal dialysis (PD) patients...
Reduction of perlecan synthesis and induction of TGF-beta1 in human peritoneal mesothelial cells due to high dialysate glucose concentration: implication in peritoneal dialysisSusan Yung
Division of Nephrology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
J Am Soc Nephrol 15:1178-88. 2004..its selective permeability, thereby impairing the peritoneal transport properties in patients on long-term peritoneal dialysis (PD)...
The effects of peritoneal dialysis solutions on peritoneal host defenseSiska Mortier
Renal Unit, University Hospital, Ghent, Belgium
Perit Dial Int 24:123-38. 2004Conventional peritoneal dialysis fluid (PDF) is a bioincompatible solution owing to the acidic pH, the high glucose concentrations and the associated hyperosmolarity, the high lactate concentrations, and the presence of glucose ..
Cyclooxygenase-2 mediates dialysate-induced alterations of the peritoneal membraneLuiz S Aroeira
Instituto Reina Sofía de Investigaciones Nefrológicas, Hospital Universitario La Paz, Madrid, Spain
J Am Soc Nephrol 20:582-92. 2009During peritoneal dialysis (PD), exposure of the peritoneal membrane to nonphysiologic solutions causes inflammation, ultimately leading to altered structure and function...
Frequencies of hepatitis B and C infections among haemodialysis and peritoneal dialysis patients in Asia-Pacific countries: analysis of registry dataDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Discipline of Public Health, University of Adelaide, Adelaide, Australia
Nephrol Dial Transplant 24:1598-603. 2009..The aim of the present investigation was to evaluate the rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections in peritoneal dialysis (PD) and haemodialysis (HD) patients in the Asia-Pacific region.
Fatigue in chronic peritoneal dialysis patientsShahrzad Ossareh
Peritoneal Dialysis Program, Toronto Western Hospital, Division of Nephrology, University of Toronto, Canada
Int Urol Nephrol 35:535-41. 2003..Anemia seems to be the most important factor associated with fatigue. Dialysis adequacy and nutritional state did not show any correlation with the frequency of fatigue in our study...
HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesotheliumMin A Yu
Division of Nephrology, Ewha University School of Medicine, YangChun Ku, Seoul, Korea
J Am Soc Nephrol 20:567-81. 2009Over time, peritoneal dialysis results in functional and structural alterations of the peritoneal membrane, but the underlying mechanisms and whether these changes are reversible are not completely understood...
NT-proBNP, fluid volume overload and dialysis modality are independent predictors of mortality in ESRD patientsRamon Paniagua
Unidad de Investigacion Medica en Enfermedades Nefrologicas, Hospital de Especialidades, CMN Siglo XXI, Mexico City
Nephrol Dial Transplant 25:551-7. 2010..It has been suggested that continuous ambulatory peritoneal dialysis (CAPD), automated peritoneal dialysis (APD) and haemodialysis (HD) may have different effects on fluid ..
Factors associated with blood concentrations of indoxyl sulfate and p-cresol in patients undergoing peritoneal dialysisChien Te Lee
Division of Nephrology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
Perit Dial Int 30:456-63. 2010..Factors relevant to indoxyl sulfate and p-cresol levels in peritoneal dialysis (PD) patients have rarely been investigated...
Efficacy of intravenous methoxy polyethylene glycol-epoetin beta administered every 2 weeks compared with epoetin administered 3 times weekly in patients treated by hemodialysis or peritoneal dialysis: a randomized trialMarian Klinger
Department of Nephrology and Transplantation Medicine, Medical University, Wroclaw, Poland
Am J Kidney Dis 50:989-1000. 2007..We examined its efficacy for Hb level correction when administered once every 2 weeks in erythropoiesis-stimulating agent-naive dialysis patients...
The efficacy of silver-ion implanted catheters in reducing peritoneal dialysis-related infectionsJohn H Crabtree
Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, Bellflower, California 90706, USA
Perit Dial Int 23:368-74. 2003..Dialysis-related infections are the commonest cause of catheter loss and transfer to hemodialysis. Surface modifications of the catheter that reduce infections are of major importance...
Analysis of depression and its effect on outcome among adult Indian peritoneal dialysis patientsSandeep Mahajan
Department of Nephrology, All India Institute of Medical Sciences, Delhi, India
Perit Dial Int 27:94-6. 2007
The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in JapanIchiro Hirahara
Division of Nephrology, Department of Medicine, Jichi Medical School, 3311 1 Yakushiji, Shimotsuke City, Tochigi 329 0498, Japan
Nephrol Dial Transplant 22:560-7. 2007Long-term peritoneal dialysis (PD) leads to peritoneal injury. At worst, peritoneal injury leads to encapsulating peritoneal sclerosis (EPS), which is a serious complication of PD. The mortality rate of EPS is extremely high...
Does diabetes mellitus predispose to increased fluid overload in peritoneal dialysis patients?Andrew Davenport
University College London Center for Nephrology, Royal Free and University College Medical School, London, UK
Nephron Clin Pract 114:c60-6. 2010Diabetic peritoneal dialysis patients have been reported to have faster peritoneal solute transport and may be at risk of reduced ultrafiltration volumes, leading to fluid overload.
Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically activeTakashi Shimada
Endocrine Unit, Thier 10, 50 Blossum Street, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 95:578-85. 2010..Design: Biologically active FGF23 in plasma from CKD patients treated by peritoneal dialysis was quantified using a cell-based Egr-1 reporter assay; bioactive FGF23 levels were compared with those ..
Change in bacterial aetiology of peritoneal dialysis-related peritonitis over 10 years: experience from a centre in South-East AsiaC C Szeto
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Clin Microbiol Infect 11:837-9. 2005This study reviewed 1787 episodes of peritoneal dialysis (PD)-related peritonitis in 544 patients between 1994 and 2003. The overall rate of peritonitis was 0.68 episodes/year of PD, but decreased from 1.10 to 0...
Biocompatibility of a bicarbonate-buffered amino-acid-based solution for peritoneal dialysisThorsten O Bender
Department of Nephrology and Medical Intensive Care, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
Pediatr Nephrol 23:1537-43. 2008Amino-acid-based peritoneal dialysis (PD) fluids have been developed to improve the nutritional status of PD patients...
Can a reduction in extracellular fluid volume result in increased serum albumin in peritoneal dialysis patients?Colin H Jones
Department of Renal Medicine, York District Hospital, York, United Kingdom
Am J Kidney Dis 39:872-5. 2002..We investigated whether decreasing dry weight increases serum albumin in peritoneal dialysis patients...
Inflammatory cytokines, angiogenesis, and fibrosis in the rat peritoneumPeter J Margetts
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
Am J Pathol 160:2285-94. 2002Peritonitis, a common complication of peritoneal dialysis, is followed by acute changes in the function of the peritoneum. The role of inflammatory cytokines in these processes is not clearly identified...
Epidemiology of peritoneal dialysis: a story of believers and nonbelieversNorbert Lameire
Renal Division, University Hospital, 185 De Pintelaan, 9000 Gent, Belgium
Nat Rev Nephrol 6:75-82. 2010..In this Review, we compare the epidemiology of peritoneal dialysis with that of hemodialysis and describe some of the major differences in the global utilization of the two ..
Biocompatible peritoneal dialysis solutions: do we have one?Kunal Chaudhary
Division of Nephrology and Hypertension, University of Missouri Columbia School of Medicine, Harry S Truman VA Medical Center, 800 Hospital Drive, Columbia, MO 65201, USA
Clin J Am Soc Nephrol 5:723-32. 2010Clinical experience and literature evidence suggest that peritoneal dialysis (PD) is a safe and effective treatment in short term (3 to 5 years) for stage 5 chronic kidney disease patients...
Gram-negative peritonitis--the Achilles heel of peritoneal dialysis?Cheuk Chun Szeto
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, PR China
Perit Dial Int 27:S267-71. 2007Peritonitis caused by gram-negative bacteria is a serious complication of peritoneal dialysis. Antibiotic resistance is common, and response to medical treatment is often poor...
Morphologic changes of peritoneum and expression of VEGF in encapsulated peritoneal sclerosis rat modelsHiroaki Io
Division of Nephrology, Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan
Kidney Int 65:1927-36. 2004Simple sclerosis consisted of a thin layer of submesothelial sclerotic tissue in peritoneal dialysis patients...
Peritoneal dialysis utilization and outcome: what are we facing?Wai Kei Lo
Department of Medicine, Tung Wah Hospital, Hong Kong SAR, PR China
Perit Dial Int 27:S42-7. 2007Penetration of peritoneal dialysis (PD) varies tremendously across the world. It ranges from about 80% in Hong Kong and Mexico to just a few percentage points in the United States, Japan, and Germany...
Predictors of baseline peritoneal transport status in Australian and New Zealand peritoneal dialysis patientsMarkus Rumpsfeld
Australia and New Zealand Dialysis and Transplant Association Registry, Adelaide, Australia
Am J Kidney Dis 43:492-501. 2004BACKGROUND: Factors that predict peritoneal transport status in peritoneal dialysis (PD) patients are poorly understood. The aim of the present study is to determine these factors in Australian and New Zealand incident PD patients...
Insulin resistance and glucose homeostasis in peritoneal dialysisPaulo Cezar Fortes
Center for Health and Biological Sciences, Pontificia Universidade Catolica do Parana, Curitiba, Brazil
Perit Dial Int 29:S145-8. 2009Cardiovascular disease (CVD) is the main cause of death in peritoneal dialysis (PD) patients, a situation that can be explained by a combination of traditional and nontraditional risk factors for CVD in these patients...
Antioxidant status of patients on peritoneal dialysis: associations with inflammation and glycoxidative stressIsabella Sundl
Human Nutrition and Metabolism Research and Training Center Graz, Institute of Molecular Sciences, Karl Franzens University, Graz, Austria
Perit Dial Int 29:89-101. 2009Patients on peritoneal dialysis (PD) frequently exhibit oxidant-antioxidant imbalance, advanced glycation end-product overload, and subclinical inflammation but the interrelations between these pathophysiological changes have not been ..
The John F. Maher Award Recipient Lecture 2006. The "heart" of peritoneal dialysis: residual renal functionAngela Yee Moon Wang
University Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
Perit Dial Int 27:116-24. 2007..The CANUSA study originally reported the importance of total small-solute clearance in predicting survival of peritoneal dialysis (PD) patients...
Coronary artery calcification, systemic inflammation markers and mineral metabolism in a peritoneal dialysis populationAdriano Luiz Ammirati
Nephrology Division, , , Brazil
Nephron Clin Pract 104:c33-40. 2006AIMS: To assess the prevalence of coronary artery calcification (CAC) in peritoneal dialysis (PD) patients and to determine whether comorbidities such as inflammation, dyslipidemia and mineral metabolism disorders correlate with its ..
High volume peritoneal dialysis for acute renal failureDaniela Ponce Gabriel
Department of Internal Medicine, University Hospital, Botucatu School of Medicine, Sao Paulo State University, Rubiao Junior, CEP 18618 970 São Paulo, SP, Brazil
Perit Dial Int 27:277-82. 2007b>Peritoneal dialysis (PD) is still widely used for acute renal failure (ARF) in developing countries despite concerns about its inadequacy...
Fungal peritonitis in peritoneal dialysis patientsNarayan Prasad
Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
Perit Dial Int 25:207-22. 2005Peritonitis is one of the most frequent complications of peritoneal dialysis (PD) and 1% - 15% of episodes are caused by fungal infections...
B-type natriuretic peptide and amino-terminal atrial natriuretic peptide predict survival in peritoneal dialysisJoost H W Rutten
Department of Internal Medicine Erasmus MC, Rotterdam, The Netherlands
Perit Dial Int 26:598-602. 2006
Omental milky spots in peritoneal pathophysiology (spots before your eyes)Robert H J Beelen
Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
Perit Dial Int 25:30-2. 2005
Quality of life and psychological issues in peritoneal dialysis patientsSusie Q Lew
Department of Medicine, George Washington University, Washington, DC, USA
Semin Dial 18:119-23. 2005Both peritoneal dialysis (PD) and hemodialysis (HD) patients have diminished quality of life (QOL) scores compared to healthy patients...
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in peritoneal dialysis: systematic review and meta-analysis of randomized controlled trialsAyub Akbari
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Perit Dial Int 29:554-61. 2009Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are widely used in clinical practice. The safety and efficacy of these agents in peritoneal dialysis (PD) patients are unclear.
Bicarbonate/lactate-based peritoneal dialysis solution increases cancer antigen 125 and decreases hyaluronic acid levelsS Jones
Institute of Nephrology, University of Wales College of Medicine, Cardiff, Wales, United Kingdom
Kidney Int 59:1529-38. 2001..In the long term, this may positively impact the peritoneal membrane, increasing its life as a dialyzing organ...
Identification and treatment of depression in a cohort of patients maintained on chronic peritoneal dialysisD Wuerth
New Haven CAPD, New Haven, CT, USA
Am J Kidney Dis 37:1011-7. 2001..as a pilot study to evaluate the feasibility of screening a large cohort of patients maintained on chronic peritoneal dialysis (CPD) for depression and then pharmacologically treating those patients assessed to have clinical ..
Acquired ultrafiltration dysfunction in peritoneal dialysis patientsPeter J Margetts
Division of Nephrology, McMaster University, Hamilton, Canada
J Am Soc Nephrol 13:2787-94. 2002
Effective use of laparoscopy for long-term peritoneal dialysis accessJohn H Crabtree
Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente, Bellflower Medical Center, Bellflower, CA, USA
Am J Surg 198:135-41. 2009Laparoscopy is an underused modality for peritoneal dialysis access procedures. The strengths of laparoscopy are that it can both prevent and resolve the common mechanical problems that adversely effect dialysis catheter outcomes.
Peritoneal dialysis favorably influences early graft function after renal transplantation compared to hemodialysisW Van Biesen
Department of Internal Medicine, University Hospital Gent, Belgium
Transplantation 69:508-14. 2000..b>Peritoneal dialysis as pretransplantation dialysis modality was reported to influence favorably the recovery of renal function ..
The impact of dialysis modality on serum heat shock proteins in children and young adults with chronic kidney diseaseKinga Musiał
Department of Pediatric Nephrology, Wrocław Medical University, Wrocław, Poland
Kidney Blood Press Res 32:366-72. 2009..The aim of the study was to evaluate the serum HSP, their connections with dialysis modality and their possible role as markers of atherosclerosis...
Vascular and other tissue calcification in peritoneal dialysis patientsAngela Yee Moon Wang
University Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR, PR China
Perit Dial Int 29:S9-S14. 2009..of cardiovascular calcification in the ESRD population, including in patients receiving long-term peritoneal dialysis (PD)...
Peritoneal sodium mass removal in continuous ambulatory peritoneal dialysis and automated peritoneal dialysis: influence on blood pressure controlO Ortega
Department of Nephrology, Hospital Severo Ochoa, Leganes, Madrid, Spain
Am J Nephrol 21:189-93. 2001Sodium and water retention is common in peritoneal dialysis patients and contributes to cardiovascular disease...
Amino Acid-based peritoneal dialysis solutions for malnutrition: new perspectivesHoey Lan Tjiong
Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
Perit Dial Int 29:384-93. 2009..Amino acid (AA)-based peritoneal dialysis (PD) solutions can induce an anabolic response in malnourished patients on continuous ambulatory PD if ..
The outcomes of continuous ambulatory and automated peritoneal dialysis are similarRajnish Mehrotra
Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California 90502, USA
Kidney Int 76:97-107. 2009Recent reports indicate a decreased mortality risk for patients on chronic peritoneal dialysis in the United States...
Guideline on targets for solute and fluid removal in adult patients on chronic peritoneal dialysisWai-Kei Lo
Department of Medicine, ting Wah Hospital, Hong Kong
Perit Dial Int 26:520-2. 2006
Icodextrin reduces mortality and the drop-out rate in Japanese peritoneal dialysis patientsRenjiro Kuriyama
Department of Nephrology, Ohme Municipal General Hospital, Japan
Adv Perit Dial 22:108-10. 2006..A total of 7808 patients across Japan who were using Baxter peritoneal dialysis (PD) solutions in 2004 were included in this cross-sectional analysis...
Chronic peritoneal dialysis in the United States: declining utilization despite improving outcomesRajnish Mehrotra
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California, USA
J Am Soc Nephrol 18:2781-8. 2007In the United States, chronic peritoneal dialysis take-on has declined among incident ESRD patients. Although increasing age, co-morbidity, and body size may explain part of this decline, other factors likely contribute...
Randomized, double-blind trial of antibiotic exit site cream for prevention of exit site infection in peritoneal dialysis patientsJudith Bernardini
Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Am Soc Nephrol 16:539-45. 2005Infection is the Achilles heel of peritoneal dialysis. Exit site mupirocin prevents Staphylococcus aureus peritoneal dialysis (PD) infections but does not reduce Pseudomonas aeruginosa or other Gram-negative infections, which are ..
TNP-470, an angiogenesis inhibitor, suppresses the progression of peritoneal fibrosis in mouse experimental modelYoko Yoshio
Second Department of Internal Medicine, Division of Renal Care Unit, Nagasaki University School of Medicine, Nagasaki, Japan
Kidney Int 66:1677-85. 2004In patients on long-term peritoneal dialysis (PD), angiogenesis and vasculopathy are observed in the peritoneum, and the degree of vascularization correlates with the area of fibrotic tissue, suggesting the involvement of angiogenesis in ..
An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysisTomasz Stompor
Department of Nephrology, Coronary Artery Disease, and Clinical Biochemistry, Medical Faculty, Jagiellonian University, Cracow, Poland
Am J Kidney Dis 41:203-11. 2003....
Serum troponin T concentration as a predictor of mortality in hemodialysis and peritoneal dialysis patientsBas Havekes
Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands
Am J Kidney Dis 47:823-9. 2006..67. No important differences were found between patients on hemodialysis or peritoneal dialysis therapy and between patients with high and low residual renal function...
Prognostic value of cardiac troponin T is independent of inflammation, residual renal function, and cardiac hypertrophy and dysfunction in peritoneal dialysis patientsAngela Yee Moon Wang
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin New Territories, Hong Kong
Clin Chem 53:882-9. 2007We investigated whether cardiac troponin T (cTnT) independently predicted outcome and added prognostic value over other clinical risk predictors in chronic peritoneal dialysis (PD) with end-stage renal disease.
Predictors of residual renal function loss in peritoneal dialysis: is previous renal transplantation a risk factor?Ana Bernardo
Nephrology Department, Hospital Amato Lusitano, Castelo Branco, Portugal
Adv Perit Dial 25:110-4. 2009Preservation of residual renal function (RRF) is an important goal in peritoneal dialysis (PD). The present study explored the factors conditioning RRF decline in a PD population. We studied 148 consecutive patients...
Effect of increased dialysate volume on peritoneal surface area among peritoneal dialysis patientsAvry Chagnac
Department of Nephrology, Rabin Medical Center Golda Campus, Tel Aviv University Medical School, Petah Tikva, Israel
J Am Soc Nephrol 13:2554-9. 2002Large dialysate volumes are often required to increase solute clearance for peritoneal dialysis patients...
Role of the renin-angiotensin system in the pathogenesis of peritoneal fibrosisHidetomo Nakamoto
Department of General Internal Medicine, Saitama Medical School, Saitama, Japan
Perit Dial Int 28:S83-7. 2008..In the present study, we evaluated the effect of an ARB, olmesartan medoxomil (CS866), on the progression of peritoneal fibrosis in peritoneal dialysis by examining its effect in a model of peritoneal fibrosis in hypertensive rats.
Peritoneal dialysis catheter removal for acute peritonitis: a retrospective analysis of factors associated with catheter removal and prolonged postoperative hospitalizationPeter Choi
Renal Unit, Charing Cross Hospital, Hammersmith Hospitals NHS Trust, London, UK
Am J Kidney Dis 43:103-11. 2004BACKGROUND: Most patients with acute peritoneal dialysis (PD) peritonitis respond to antibiotic therapy, but a significant minority of patients require surgical catheter removal to eradicate the infection...
Clinical experience with tamoxifen in peritoneal fibrosing syndromesGloria del Peso
Department of Nephrology, University Hospital La Paz, Madrid, Spain
Adv Perit Dial 19:32-5. 2003Peritoneal sclerosis is one of the most important complications of peritoneal dialysis (PD) treatment. Encapsulating peritoneal sclerosis (EPS) represents the most advanced stage of that disease and has a high mortality...
Subcutaneous administration of darbepoetin alfa effectively maintains hemoglobin concentrations at extended dose intervals in peritoneal dialysis patientsYu Wei Fang
Division of Nephrology, Department of Internal Medicine, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan
Perit Dial Int 29:199-203. 2009..The purpose of this single-center single-arm study was to determine whether darbepoetin alfa, when administered at extended dose intervals, is as effective as rHuEPO for the treatment of renal anemia in patients on peritoneal dialysis.
Serum fibroblast growth factor-21 concentration is associated with residual renal function and insulin resistance in end-stage renal disease patients receiving long-term peritoneal dialysisSeung Hyeok Han
Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
Metabolism 59:1656-62. 2010..markers, and metabolic parameters in healthy people (n = 63) and nondiabetic patients receiving peritoneal dialysis (PD, n = 72)...
Preliminary evaluation of incremental peritoneal dialysis in 25 patientsA F De Vecchi
Peritoneal Dialysis Program, Division of Nephrology and Dialysis, IRCCS Ospedale Maggiore Policlinico di Milano, Italy
Perit Dial Int 20:412-7. 2000..Incremental dialysis has been suggested for patients with some residual renal function. However, very little published clinical data exist on the feasibility of this schedule...
The fate of older diabetic patients on peritoneal dialysis: myths and mysteries and suggestions for further researchSteven Van Laecke
Renal Division, Department of Internal Medicine, University Hospital Ghent, Belgium
Perit Dial Int 27:611-8. 2007The outcome of older and especially of female diabetic patients appears to be worse on peritoneal dialysis (PD) than on hemodialysis (HD)...
Systemic and intraperitoneal interleukin-6 system during the first year of peritoneal dialysisRoberto Pecoits-Filho
Division of Renal Medicine and Baxter Novum, Karolinska Institutet, K 56, Huddinge University Hospital, 141 86 Stockholm, Sweden
Perit Dial Int 26:53-63. 2006..To investigate if intraperitoneal and systemic interleukin-6 (IL-6) and soluble IL-6 receptor (sIL-6R) are related to each other and to peritoneal solute transport rate (PSTR)...
Resumption of peritoneal dialysis after transcutaneous treatment of a peritoneal leakage using fibrin glueKay Herbrig
Nephrol Dial Transplant 21:2037-8. 2006
Role of aldose reductase in the peritoneal changes of patients undergoing peritoneal dialysisYukiko Hasuike
Department of Nephrology and Dialysis, Hyogo College of Medicine, Hyogo, Japan
Am J Nephrol 27:622-9. 2007The mesothelium of patients undergoing peritoneal dialysis (PD) is exposed to glucose in dialysate. Glucose metabolites 3-deoxyglucosone and advanced glycation endproducts (AGEs) in the PD fluid induce peritoneal damage...
Clinical effects of combined therapy with peritoneal dialysis and hemodialysisHideki Kawanishi
Tsuchiya General Hospital, Hiroshima, Japan
Perit Dial Int 27:S126-9. 2007..When peritoneal dialysis (PD) patients cannot maintain target clearances, the dialysis dose needs to be increased...
Development of a computer-aided diagnosis system for a new modality of renal replacement therapy: an integrated approach combining both peritoneal dialysis and hemodialysisHiroyuki Hamada
Laboratory for Bioinformatics, Graduate School of Systems Life Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
Comput Biol Med 35:845-61. 2005..clinical test for the chronic renal disease patient who needs an integrated approach that combines both peritoneal dialysis and hemodialysis (PD-HD therapy)...
Long-term effect of peritoneal dialysis fluid with neutral pH and low glucose degradation product concentration on peritoneum: a case reportHideki Shimizu
Division of Total Renal Care Medicine; Department of Nephrology and Endocrinology, University of Tokyo School of Medicine, Japan
Perit Dial Int 27:92-4. 2007
[Fluid and sodium balance and blood pressure control in APD/CAPD]P Freida
Service de Nephrologie, CHPC Hôpital Louis Pasteur 46 rue du val de Saire 50102 Cherbourg Octeville, France
Nephrol Ther 3:S170-7. 2007..Further studies should be conducted to assess the power of innovative PD solutions--Low Sodium PDF and/or Bimodal Ultrafiltration--in enhancing fluid and sodium removal during CAPD/APD programmes...
Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factorLuiz S Aroeira
, Hospital Universitario de la Princesa, Madrid, Spain
Am J Kidney Dis 46:938-48. 2005BACKGROUND: During peritoneal dialysis (PD), the peritoneum is exposed to bioincompatible dialysis fluids that cause epithelial-to-mesenchymal transition of mesothelial cells, fibrosis, and angiogenesis...
The contribution of free water transport and small pore transport to the total fluid removal in peritoneal dialysisAlena Parikova
Division of Nephrology, Department of Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Kidney Int 68:1849-56. 2005Water transport in peritoneal dialysis (PD) patients is across the small pores and water channels, the latter allowing free water transport...
Research Grants
- Stent Lock Mechanism for Transcutaneous CathetersNICHOLAS VITALE; Fiscal Year: 2005b>Peritoneal dialysis, intravascular access for chemotherapy, transcutaneous intrathoracic access of cardiac power lines, and suprapubic bladder drainage are among the clinical applications where transcutaneous catheters are routinely used ..
- REGULATION OF BONE FORMATION IN RENAL OSTEODYSTROPHYIsidro B Salusky; Fiscal Year: 2004..on bone formation and parathyroid gland function in children with bone biopsy proven 2-HPT and treated with peritoneal dialysis. Also the response to these two vitamin D sterols will be assessed in patients given calcium carbonate or a ..
- Effects of Hyaluronan on Interstitial ConvectionMICHAEL FLESSNER; Fiscal Year: 2007..to quantify solute diffusion and convection in the subperitoneal muscle of anesthetized rats during peritoneal dialysis. The in vivo model permits control of the tissue pressure forces and measurement of the pressure profile ..
- Dynamics of Peritoneal Dialysis Associated PeritonitisJohn Hotchkiss; Fiscal Year: 2004..on interactions between dynamics of bacterial growth and optimal bacterial clearance in the setting of peritoneal dialysis associated peritonitis (PDAP)...
- CALCITRIOL THERAPY ON DIALYZED CHILDRENISIDRO SALUSKY; Fiscal Year: 1993..calcitriol will be performed in pediatric patients with secondary hyperparathyroidism and treated with peritoneal dialysis. Therapeutic responses will be judged by changes in biochemical indices of parathyroid hormone secretion ..
- ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASEAlan Christensen; Fiscal Year: 2003..g., continuous ambulatory peritoneal dialysis) but poorer adherence when receiving staff administered dialysis (e.g., center hemodialysis)...
- Assessing Functional Outcomes in Adolescent with ESRDSusan Furth; Fiscal Year: 2002..quality of life (HRQL) for pediatric patients with chronic renal failure or ESRD treated with hemodialysis, peritoneal dialysis or transplant. Resources provided by the RO3 award will allow Dr...
- PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULESMICHAEL FLESSNER; Fiscal Year: 2004..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
- S.T.R.A.P Sonos Transportable Renal Application ProductMartin Roberts; Fiscal Year: 2005..5 billion. Hemodialysis requires patient treatment 3 times a week for 3-4 hours. Peritoneal dialysis is an option utilized by less than 10% of patients requiring manual exchange of 2 liters of dialysate every ..
- An all titanium transcutaneous access device (TAD) for peritoneal dialysisRobert Whalen; Fiscal Year: 2007Chronic transcutaneous access is needed for peritoneal dialysis (PD) and new emerging medical therapies...
- DIURNAL AND PULSATILE PTH SECRETION IN RENAL FAILUREWilliam Goodman; Fiscal Year: 2001..with secondary hyperparathyroidism will also be evaluated, and the respective roles of hemodialysis and peritoneal dialysis as separate modifiers of diurnal and pulsatile PTH secretion in end-stage renal disease will be examined...
- Acute Renal Failure Mediated Lung InjurySarah Faubel; Fiscal Year: 2009..if the uremic factors that stimulate IL-6 production in AKI may be removed by dialysis, the effect of acute peritoneal dialysis on IL-6 production and serum IL-6 will be determined...
- Acute Renal Failure Mediated Lung InjurySarah Faubel; Fiscal Year: 2010..if the uremic factors that stimulate IL-6 production in AKI may be removed by dialysis, the effect of acute peritoneal dialysis on IL-6 production and serum IL-6 will be determined...
- Dietary Adherence Enhancement in Peritoneal DialysisMARY SEVICK; Fiscal Year: 2007..study will pilot test an intervention! based on self-efficacy theory, to improve adherence to the peritoneal dialysis dietary regimen...
- Patient-Oriented Research in Kidney DiseaseNeil Powe; Fiscal Year: 2007..This is a national prospective cohort study comparing treatment and outcomes in hemodialysis and peritoneal dialysis patients...
- LONG-TERM PERCUTANEOUS ACCESS DEVICE FOR HOME THERAPIESLUDMILA BERNSTAM; Fiscal Year: 2005..devices for treatment of chronic heart failure, total parenteral nutrition, drug delivery, and ambulatory peritoneal dialysis. The PAD is pre-seeded with autologous fibroblasts derived from a small sample of the recipient's skin...
