Genomes and Genes
Summary: Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.
Publications301 found, 100 shown here
- Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventionsLuiz S Aroeira
Unidad de Biologia Molecular, Hospital Universitario de la Princesa, C Diego de Leon 62, Madrid, Spain
J Am Soc Nephrol 18:2004-13. 2007b>Peritoneal dialysis (PD) is a form of renal replacement and is based on the use of the peritoneum as a semipermeable membrane across which ultrafiltration and diffusion take place...
- Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factorLuiz S Aroeira
Servicio de Nefrologia, Hospital Universitario de la Princesa, Madrid, Spain
Am J Kidney Dis 46:938-48. 2005During peritoneal dialysis (PD), the peritoneum is exposed to bioincompatible dialysis fluids that cause epithelial-to-mesenchymal transition of mesothelial cells, fibrosis, and angiogenesis...
- Morphologic changes in the peritoneal membrane of patients with renal diseaseJohn D Williams
Institute of Nephrology, University of Wales College of Medicine, Cardiff, United Kingdom
J Am Soc Nephrol 13:470-9. 2002This study examined the morphologic features of the parietal peritoneal membranes of 130 patients undergoing peritoneal dialysis (PD) and compared them with the features of the peritoneal membranes of normal individuals, uremic ..
- The pathophysiology of the peritoneal membraneOlivier Devuyst
Division of Nephrology, UCL Medical School, 10 Avenue Hippocrate, B 1200 Brussels, Belgium
J Am Soc Nephrol 21:1077-85. 2010The development of peritoneal dialysis (PD) as a successful therapy has and still depends on experimental models to test and understand critical pieces of pathophysiology...
- Cu/Zn ratios are associated with nutritional status, oxidative stress, inflammation, and immune abnormalities in patients on peritoneal dialysisChih Hung Guo
Institute of Biomedical Nutrition, Hung Kuang University, Taichung 433, Taiwan, ROC
Clin Biochem 44:275-80. 2011We evaluated the relationship of the plasma copper/zinc (Cu/Zn) ratio with nutritional status, inflammation, oxidative stress, and immune function in peritoneal dialysis patients.
- Basic mechanisms and clinical implications of peritoneal fibrosisPeter J Margetts
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Perit Dial Int 23:530-41. 2003..Clinical trials to assess the role of prevention of peritoneal injury using biocompatible solutions and treatments targeted directly at peritoneal fibrosis will be important, but challenging to design and carry out...
- HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesotheliumMin A Yu
Division of Nephrology, Ewha University School of Medicine, YangChun Ku, Seoul, Korea
J Am Soc Nephrol 20:567-81. 2009Over time, peritoneal dialysis results in functional and structural alterations of the peritoneal membrane, but the underlying mechanisms and whether these changes are reversible are not completely understood...
- Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patientsEric D Weinhandl
Chronic Disease Research Group, Minneapolis, MN 55404, USA
J Am Soc Nephrol 21:499-506. 2010Contemporary comparisons of mortality in matched hemodialysis and peritoneal dialysis patients are lacking...
- Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA studyJ M Bargman
Division of Nephrology, Toronto General Hospital, University of Toronto, 200 Elizabeth Street EN10 216, Toronto, Ontario M5G 2C4, Canada
J Am Soc Nephrol 12:2158-62. 2001Studies of the adequacy of peritoneal dialysis and recommendations have assumed that renal and peritoneal clearances are comparable and therefore additive. The CANUSA data were reanalyzed in an effort to address this assumption...
- Tamoxifen is associated with lower mortality of encapsulating peritoneal sclerosis: results of the Dutch Multicentre EPS StudyMario R Korte
Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands
Nephrol Dial Transplant 26:691-7. 2011Encapsulating peritoneal sclerosis (EPS) is a serious complication of peritoneal dialysis (PD) with an increasing incidence...
- Recurrent and atypical posterior reversible encephalopathy syndrome in a child with peritoneal dialysisIlknur Girişgen
Department of Pediatrics, Adnan Menderes University Faculty of Medicine, Aydm, Turkey
Turk J Pediatr 52:416-9. 2010..this article, we present recurrent atypical PRES in a hypertensive child with end-stage renal disease on a peritoneal dialysis program as a rare case and we discuss recurrence...
- Survival analysis: comparing peritoneal dialysis and hemodialysis in TaiwanChiu Ching Huang
Department of Medicine and Biostatistics Center, China Medical University, Taiwan
Perit Dial Int 28:S15-20. 2008Comparisons of survival in patients on peritoneal dialysis (PD) and on hemodialysis (HD) have been conducted in many Western countries, but publications on this subject in Asian populations are scarce...
- Serum albumin as a predictor of mortality in peritoneal dialysis: comparisons with hemodialysisRajnish Mehrotra
Division of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
Am J Kidney Dis 58:418-28. 2011..Whether the threshold level of serum albumin at which mortality risk increases in peritoneal dialysis (PD) patients is the same as for hemodialysis (HD) patients has not been studied.
- Broadening Options for Long-term Dialysis in the Elderly (BOLDE): differences in quality of life on peritoneal dialysis compared to haemodialysis for older patientsEdwina A Brown
Imperial College Kidney and Transplant Institute, Hammersmith Hospital, London, UK
Nephrol Dial Transplant 25:3755-63. 2010..Little is, however, known about differences in QOL on haemodialysis (HD) and peritoneal dialysis (PD) in older age groups. Randomising patients to either modality to assess outcomes is not feasible.
- Frequencies of hepatitis B and C infections among haemodialysis and peritoneal dialysis patients in Asia-Pacific countries: analysis of registry dataDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Discipline of Public Health, University of Adelaide, Adelaide, Australia
Nephrol Dial Transplant 24:1598-603. 2009..The aim of the present investigation was to evaluate the rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections in peritoneal dialysis (PD) and haemodialysis (HD) patients in the Asia-Pacific region.
- Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysisGareth W Roberts
Institute of Nephrology, School of Medicine, Cardiff University, Heath Park, Cardiff, Wales, UK
J Am Soc Nephrol 20:1895-900. 2009..peritonitis adversely affect the structure and function of the peritoneal membrane in patients treated with peritoneal dialysis (PD), but the underlying mechanisms are not well understood...
- Body composition, hydration, and related parameters in hemodialysis versus peritoneal dialysis patientsIsabel Devolder
Renal Division, University Hospital Ghent, Ghent, Belgium
Perit Dial Int 30:208-14. 2010..A new multifrequency bioimpedance tool has recently been validated. This study compares volume status in peritoneal dialysis (PD) and hemodialysis (HD) patients in a single center.
- The influence of dialysate calcium on progression of arterial stiffness in peritoneal dialysis patientsMeltem Sezis Demirci
Division of Nephrology, Ege University School of Medicine, Izmir, Turkey
Perit Dial Int 29:S15-7. 2009One of the origins of cardiovascular disease in dialysis patients is arterial stiffness. The aim of our study was to assess the relationship between the calcium content of peritoneal dialysis (PD) solution and arterial stiffness.
- Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in VietnamNguyen Hoan Phu
Center for Tropical Diseases, Center for Tropical Diseases, Cho Quan Hospital, Ho Chi Minh City, Vietnam
N Engl J Med 347:895-902. 2002In some parts of the world, peritoneal dialysis is widely used for renal replacement in acute renal failure...
- PPAR-γ agonist rosiglitazone protects peritoneal membrane from dialysis fluid-induced damagePilar Sandoval
Unidad de Biologia Molecular, Hospital Universitario de la Princesa, Madrid, Spain
Lab Invest 90:1517-32. 2010Exposure to non-physiological solutions during peritoneal dialysis (PD) produces structural alterations to the peritoneal membrane and ultrafiltration dysfunction...
- Encapsulating peritoneal sclerosis--a clinician's approach to diagnosis and medical treatmentHidetomo Nakamoto
Department of Nephrology, Tokorozawa Kidney Clinic, Tokorozawa, Japan
Perit Dial Int 25:S30-8. 2005Encapsulating peritoneal sclerosis (EPS) is recognized as a serious complication of continuous peritoneal dialysis. A preliminary diagnosis of EPSis usually based on clinical signs and symptoms, which commonly include abdominal pain, ..
- Peritonitis remains the major clinical complication of peritoneal dialysis: the London, UK, peritonitis audit 2002-2003Andrew Davenport
UCL Centre for Nephrology, Royal Free and University College Medical School, London, United Kingdom
Perit Dial Int 29:297-302. 2009Over the past two decades, the rate of peritonitis in patients treated by peritoneal dialysis (PD) has been significantly reduced...
- Predictors of loss of residual renal function among new dialysis patientsL M Moist
Department of Medicine, University of Western Ontario, London, Canada
J Am Soc Nephrol 11:556-64. 2000..to determine the predictors of RRF loss in a national random sample of patients initiating hemodialysis and peritoneal dialysis. The study controlled for baseline variables and included major predictors...
- Geographic and educational factors and risk of the first peritonitis episode in Brazilian Peritoneal Dialysis study (BRAZPD) patientsLuis C Martin
Department of Internal Medicine, Botucatu Medical School, 18618 000 Botucatu, Sao Paulo, Brazil
Clin J Am Soc Nephrol 6:1944-51. 2011Peritonitis remains as the most frequent cause of peritoneal dialysis (PD) failure, impairing patient's outcome...
- Peritoneal dialysis-associated peritonitis in Scotland (1999-2002)David Kavanagh
The Scottish Renal Registry, Royal Infirmary, Castle Street, Glasgow G4 0SF, UK
Nephrol Dial Transplant 19:2584-91. 2004Peritonitis is a major complication of peritoneal dialysis (PD). We have performed a national study of all patients on PD in Scotland over a 3...
- Initial glucose load predicts technique survival in patients on chronic peritoneal dialysisHon Yen Wu
Department of Internal Medicine, Yun Lin branch, National Taiwan University Hospital, Yun Lin, Taiwan
Am J Nephrol 28:765-71. 2008A high glucose content in peritoneal dialysis (PD) solution may result in unfavorable changes on peritoneal character and worsened metabolic profiles...
- Peritoneal dialysis patient survival: a comparison between a Swedish and a Korean centreSung Hee Chung
Hyonam Kidney Laboratory, Soon Chun Hyang University, 657 Hannam Dong, Yongsan Ku, Seoul 140 743, Korea
Nephrol Dial Transplant 20:1207-13. 2005Dialysis patient mortality remains high, and this high mortality may be due to many factors. In peritoneal dialysis (PD) patients, old age, co-morbid diseases, malnutrition, low residual renal function (RRF) and a high peritoneal ..
- Ex vivo analysis of dialysis effluent-derived mesothelial cells as an approach to unveiling the mechanism of peritoneal membrane failureManuel López-Cabrera
Unidad de Biologia Molecular, Hospital Universitario de la Princesa, Diego de Leon, 62, 28006 Madrid, Spain
Perit Dial Int 26:26-34. 2006During peritoneal dialysis (PD), the peritoneum is exposed to bioincompatible dialysis fluids, which causes progressive fibrosis and angiogenesis and, ultimately, ultrafiltration failure...
- Higher rate and earlier peritonitis in Aboriginal patients compared to non-Aboriginal patients with end-stage renal failure maintained on peritoneal dialysis in Australia: analysis of ANZDATAWai H Lim
Renal Unit, Queen Elizabeth Hospital, Adelaide, South Australia, Australia
Nephrology (Carlton) 10:192-7. 2005Aboriginal patients maintained on peritoneal dialysis (PD) have a higher rate of technique failure than any other racial group in Australia...
- Cardiovascular problems in dialysis patients: impact on survivalManavjot S Sidhu
Department of Internal Medicine, University of Missouri, Columbia, Missouri 65212, USA
Adv Perit Dial 26:47-52. 2010..from clinical trials, data from randomized controlled trials regarding outcomes in patients undergoing peritoneal dialysis are almost absent...
- Global trends in rates of peritoneal dialysisArsh K Jain
Division of Nephrology, University of Western Ontario, London, Canada
J Am Soc Nephrol 23:533-44. 2012Although there is a perception that the use of peritoneal dialysis is declining worldwide, compilations of global data are unavailable to test this hypothesis...
- Inflammatory cytokines, angiogenesis, and fibrosis in the rat peritoneumPeter J Margetts
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
Am J Pathol 160:2285-94. 2002Peritonitis, a common complication of peritoneal dialysis, is followed by acute changes in the function of the peritoneum. The role of inflammatory cytokines in these processes is not clearly identified...
- Cancer in patients on chronic dialysis in KoreaJung Eun Lee
Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
J Korean Med Sci 24:S95-S101. 2009..3%) out of 4,562 end-stage renal disease (ESRD) patients maintained on hemodialysis (HD) or peritoneal dialysis (PD) at Yonsei University Health System from 1996 to 2005...
- Encapsulating peritoneal sclerosis in the new millennium: a national cohort studyMichaela C Brown
Scottish Renal Registry, Royal Infirmary, Glasgow, UK
Clin J Am Soc Nephrol 4:1222-9. 2009The study aim was to establish the incidence and characterize all encapsulating peritoneal sclerosis (EPS) cases in patients treated by peritoneal dialysis (PD).
- Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosisHideki Yokoi
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan
Kidney Int 81:160-9. 2012Long-term peritoneal dialysis induces peritoneal fibrosis with submesothelial fibrotic tissue. Although angiogenesis and inflammatory mediators are involved in peritoneal fibrosis, precise molecular mechanisms are undefined...
- Peritoneal mast cells in peritoneal dialysis patients, particularly in encapsulating peritoneal sclerosis patientsDominik M Alscher
Department of Internal Medicine, Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, Stuttgart, Germany
Am J Kidney Dis 49:452-61. 2007..that increased mast cell numbers contribute substantially to the fibrosis often seen in the peritoneum of peritoneal dialysis (PD) patients, particularly those with encapsulating peritoneal fibrosis (EPS)...
- The effects of renin-angiotensin system inhibition on regression of encapsulating peritoneal sclerosisDevrim Bozkurt
Department of Nephrology, Ege University, Izmir, Turkey
Perit Dial Int 28:S38-42. 2008..b>Peritoneal dialysis (PD) patients rarely develop EPS, a severe life-threatening condition of unknown pathogenesis...
- The role of the TGF/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutionsQiang Yao
Divisions of Baxter Novum and Renal Medicine, Department of Clinical Science, Karolinska Institutet, Stockholm, Sweden
Nephron Exp Nephrol 109:e71-8. 2008b>Peritoneal dialysis (PD) solutions contribute to peritoneal membrane damage...
- Peritoneal changes after exposure to sterile solutions by catheterMichael F Flessner
Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
J Am Soc Nephrol 18:2294-302. 2007..These findings confirm the hypothesis that the presence of a PC catheter increases inflammatory response to sterile solutions as evidenced by the structural and functional changes in the peritoneal barrier...
- Mesothelial cellsSusan Yung
Department of Medicine, University of Hong Kong, Hong Kong SAR, PR China
Perit Dial Int 27:S110-5. 2007The introduction of peritoneal dialysis (PD) as a modality of renal replacement therapy has provoked much interest in the biology of the peritoneal mesothelial cell...
- Cost comparison of peritoneal dialysis versus hemodialysis in end-stage renal diseaseAriel Berger
Policy Analysis, Inc, Four Davis Ct, Brookline, MA 02445, USA
Am J Manag Care 15:509-18. 2009To compare healthcare utilization and costs in patients with end-stage renal disease (ESRD) beginning peritoneal dialysis (PD) or hemodialysis (HD).
- Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cellsSonja Mandl-Weber
Nephrologisches Zentrum, Medizinische Klinik und Poliklinik Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
Kidney Int 61:570-8. 2002Vascular endothelial growth factor (VEGF) was recently found in peritoneal effluents of peritoneal dialysis (PD) patients...
- Severe vitamin D deficiency in chronic renal failure patients on peritoneal dialysisH Taskapan
Inonu University Medical School, Department of Medicine, Division of Nephrology, Malatya, Turkey
Clin Nephrol 66:247-55. 2006The aim of this study was to evaluate the prevalence of vitamin D deficiency in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with various demographic and renal osteodystrophy markers.
- Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysisJ Ni
Division of Nephrology and Department of Pathology, UCL Medical School, Brussels, Belgium
Kidney Int 69:1518-25. 2006..of the implication of AQP1 in solute-free water transport, sodium sieving, and ultrafiltration (UF) during peritoneal dialysis (PD) is lacking, and the effects of its deletion on the structure of the membrane are unknown...
- Increases in serum leptin levels during peritoneal dialysis are associated with inflammation and a decrease in lean body massP Stenvinkel
Division of Renal Medicine, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
J Am Soc Nephrol 11:1303-9. 2000..elevated leptin levels have been documented in uremic patients, especially in those who are treated by peritoneal dialysis (PD)...
- Serum matrix metalloproteinases MMP-2 and MMP-3 levels in dialysis patients vary independently of CRP and IL-6 levelsGloria A Preston
Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Nephron 92:817-23. 2002Patients on chronic hemodialysis or peritoneal dialysis often develop an inflammatory state that causes morbidity and mortality...
- Sodium removal in patients undergoing CAPD and automated peritoneal dialysisAna Rodriguez-Carmona
Division of Nephrology, Hospital Juan Canalejo, A Coruna, Spain
Perit Dial Int 22:705-13. 2002To compare sodium removal in continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) patients, and to identify the main factors that modify Na removal in clinical practice in these patients.
- Impact of ACE inhibitors and AII receptor blockers on peritoneal membrane transport characteristics in long-term peritoneal dialysis patientsInna Kolesnyk
Division of Nephrology, Academic Medical Center, Amsterdam, The Netherlands
Perit Dial Int 27:446-53. 2007Long-term peritoneal dialysis (PD) may lead to peritoneal fibrosis and ultrafiltration failure. The latter occurs due to high solute transport rates and diabetiform peritoneal sclerosis...
- Computed tomographic findings characteristic for encapsulating peritoneal sclerosis: a case-control studyAnniek Vlijm
Department of Medicine, University of Amsterdam, Amsterdam, The Netherlands
Perit Dial Int 29:517-22. 2009..To establish CT findings characteristic for EPS, we compared CT findings between EPS patients and long-term peritoneal dialysis (PD) patients without EPS.
- Glycemic control and survival in peritoneal dialysis patients with diabetes mellitusUyen Duong
Harold Simmons Center for Chronic Disease Research and Epidemiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90509 2910, USA
Clin J Am Soc Nephrol 6:1041-8. 2011The optimal target for glycemic control has not been established for diabetic peritoneal dialysis (PD) patients.
- Oral paricalcitol for the treatment of secondary hyperparathyroidism in patients on hemodialysis or peritoneal dialysisEdward A Ross
Division of Nephrology, Hypertension, and Transplantation, University of Florida, Gainesville, FL 32610 0224, USA
Am J Nephrol 28:97-106. 2008..This study investigates the effects of oral paricalcitol to reduce PTH in patients receiving chronic HD and peritoneal dialysis (PD).
- Charlson comorbidity index as a predictor of outcomes in incident peritoneal dialysis patientsL Fried
Renal Section, VA Pittsburgh Healthcare System, and Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Kidney Dis 37:337-42. 2001..The purpose of this study was to examine the usefulness of the CCI as a predictor in incident peritoneal dialysis (PD) patients and to examine whether it was a better predictor than simply the number of comorbid ..
- Effect of fluid and sodium removal on mortality in peritoneal dialysis patientsK Ates
Ankara University Medical School, Ibn i Sina Hospital, Department of Nephrology, Ankara, Turkey
Kidney Int 60:767-76. 2001Effect of fluid and sodium removal on mortality in peritoneal dialysis patients.
- NT-proBNP, fluid volume overload and dialysis modality are independent predictors of mortality in ESRD patientsRamon Paniagua
Unidad de Investigacion Medica en Enfermedades Nefrologicas, Hospital de Especialidades, CMN Siglo XXI, Mexico City
Nephrol Dial Transplant 25:551-7. 2010..It has been suggested that continuous ambulatory peritoneal dialysis (CAPD), automated peritoneal dialysis (APD) and haemodialysis (HD) may have different effects on fluid ..
- Survival advantages of obesity in dialysis patientsKamyar Kalantar-Zadeh
Division of Nephrology and Hypertension, Los Angeles Biomedical Institute at Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
Am J Clin Nutr 81:543-54. 2005..or dialysis-risk-paradox is relatively consistent in MHD patients, studies in CKD patients undergoing peritoneal dialysis have yielded mixed results...
- The progression and impact of vascular calcification in peritoneal dialysis patientsAdriano Luiz Ammirati
Nephrology Division, Federal University of Sao Paulo, 282 Pedro de Toledo Street, São Paulo 04039 000, Brazil
Perit Dial Int 27:340-6. 2007..Little information is available regarding peritoneal patients...
- Cardiovascular risk in the peritoneal dialysis patientRaymond T Krediet
Division of Nephrology, Department of Medicine, Academic Medical Centre University of Amsterdam, P O Box 22700, 1100 DE Amsterdam, The Netherlands
Nat Rev Nephrol 6:451-60. 2010Cardiovascular death is the most frequent cause of death in patients on peritoneal dialysis. Risk factors for cardiovascular death in these patients include those that affect the general population as well as those related to end-stage ..
- Similar outcomes with hemodialysis and peritoneal dialysis in patients with end-stage renal diseaseRajnish Mehrotra
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
Arch Intern Med 171:110-8. 2011The annual payer costs for patients treated with peritoneal dialysis (PD) are lower than with hemodialysis (HD), but in 2007, only 7% of dialysis patients in the United States were treated with PD...
- Continuous peritoneal dialysis-associated peritonitis: a review and current conceptsLaura Troidle
New Haven CAPD, Renal Research Institute, New Haven, Connecticut, USA
Semin Dial 16:428-37. 2003The percentage of end-stage renal disease (ESRD) patients in the United States maintained on continuous peritoneal dialysis (CPD) therapy is decreasing...
- The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membraneJohn D Williams
Institute of Nephrology, University Hospital of Wales College of Medicine, Heath Park, Cardiff, Wales, UK
Kidney Int 66:408-18. 2004Although peritoneal dialysis (PD) is a widely accepted form of renal replacement therapy (RRT), concerns remain regarding the bioincompatible nature of standard PD fluid...
- Peritoneal dialysis in the 21st century: an analysis of current problems and future developmentsRam Gokal
Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom
J Am Soc Nephrol 13:S104-16. 2002
- Peritoneal glucose exposure and changes in membrane solute transport with time on peritoneal dialysisS J Davies
Department of Nephrology, North Staffordshire Hospitals Trust, Stoke on Trent, United Kingdom
J Am Soc Nephrol 12:1046-51. 2001Peritoneal solute transport increases with time on treatment in a proportion of peritoneal dialysis (PD) patients, contributing to ultrafiltration failure...
- Changes in quality of life during hemodialysis and peritoneal dialysis treatment: generic and disease specific measuresAlbert W Wu
Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Am Soc Nephrol 15:743-53. 2004..20 yr of use, relative differences in health-related quality of life (HRQOL) between hemodialysis (HD) and peritoneal dialysis (PD) are not clearly known...
- The differential impact of risk factors on mortality in hemodialysis and peritoneal dialysisEdward F Vonesh
Baxter Healthcare Corporation, Applied Statistics Center, Round Lake, Illinois 60073, USA
Kidney Int 66:2389-401. 2004..Trends in available data indicate the relative risk of death with hemodialysis (HD) compared to peritoneal dialysis (PD) varies by time on dialysis and the presence of various risk factors...
- Icodextrin improves the fluid status of peritoneal dialysis patients: results of a double-blind randomized controlled trialSimon J Davies
University Hospital of North Staffordshire, Stoke on Trent, England
J Am Soc Nephrol 14:2338-44. 2003Worsening fluid balance results in reduced technique and patient survival in peritoneal dialysis. Under these conditions, the glucose polymer icodextrin is known to enhance ultrafiltration in the long dwell...
- Mortality and technique failure in patients starting chronic peritoneal dialysis: results of The Netherlands Cooperative Study on the Adequacy of Dialysis. NECOSAD Study GroupK J Jager
Department of Nephrology, Academic Medical Center, University of Amsterdam, The Netherlands
Kidney Int 55:1476-85. 1999..The aim of this study was to determine the relative importance of baseline patient and treatment characteristics to mortality and technique failure in patients starting peritoneal dialysis.
- The relationship between the soluble Klotho protein and the residual renal function among peritoneal dialysis patientsTetsu Akimoto
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
Clin Exp Nephrol 16:442-7. 2012..The purpose of the present study was to determine the relationship between the soluble form of Klotho and renal function in chronic peritoneal dialysis (PD) patients, a relationship which remains poorly understood.
- Prospective randomized study for comparison of open surgery with laparoscopic-assisted placement of Tenckhoff peritoneal dialysis catheter--a single center experience and literature reviewShyh Chuan Jwo
Division of General Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC
J Surg Res 159:489-96. 2010The ideal method for catheter placement in patients undergoing peritoneal dialysis remains debatable. This prospective study intends to clarify whether laparoscopic assisted percutaneous puncture is superior to open surgery.
- Mini-laparoscopy-assisted placement of Tenckhoff catheters: an improved technique to facilitate peritoneal dialysisCharlotte A Batey
Division of Urology, Department of Surgery, University of Kentucky, 800 Rose Street, Lexington, KY 40536 0084, USA
J Endourol 16:681-4. 2002Despite its overall efficacy and patient satisfaction with it, peritoneal dialysis has a history of significant complications, which has contributed to the evolution in the technique from open laparotomy to minimally invasive placement ..
- Laparoscopic-assisted peritoneal dialysis catheter placement: a microinvasive techniqueSergio A Carrillo
Department of Surgery, University of Louisville, Louisville, KY 40202, USA
Surg Endosc 21:825-9. 2007b>Peritoneal dialysis is an alternate form of dialysis for patients with end-stage renal disease (ESRD)...
- Remote indigenous peritoneal dialysis patients have higher risk of peritonitis, technique failure, all-cause and peritonitis-related mortalityWai H Lim
Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia
Nephrol Dial Transplant 26:3366-72. 2011..Because many indigenous patients live in remote areas, peritoneal dialysis (PD) is often preferred...
- Recent concepts in the molecular biology of the peritoneal membrane - implications for more biocompatible dialysis solutionsSiska Mortier
Renal Division, University Hospital, De Pintelaan, Ghent, Belgium
Blood Purif 21:14-23. 2003..The structural and functional alterations in the membrane in long-term peritoneal dialysis are thought to be the consequence of the toxicity of glucose, either directly or indirectly through the ..
- Plasma levels of soluble receptor for advanced glycation end products (sRAGE) and proinflammatory ligand for RAGE (EN-RAGE) are associated with carotid atherosclerosis in patients with peritoneal dialysisJwa Kyung Kim
Department of Internal Medicine and Kidney Research Institute, Hallym University College of Medicine, Anyang, Republic of Korea
Atherosclerosis 220:208-14. 2012..We determined the levels of sRAGE and EN-RAGE in peritoneal dialysis (PD) patients and evaluated their relationship with carotid atherosclerosis.
- Encapsulating peritoneal sclerosis: the state of affairsMario R Korte
Albert Schweitzer Hospital, Department of Internal Medicine, PO Box 444, 3300 AK Dordrecht, The Netherlands
Nat Rev Nephrol 7:528-38. 2011Encapsulating peritoneal sclerosis (EPS) is a severe complication of long-term peritoneal dialysis (PD) with a 50% mortality rate...
- Can increased dietary fibre reduce laxative requirement in peritoneal dialysis patients?Debbie Sutton
Wessex Renal and Transplant Service, Queen Alexandra Hospital, Portsmouth, UK
J Ren Care 33:174-8. 2007Constipation is an important cause of technique failure and poor dialysis efficiency in Peritoneal Dialysis (PD) patients. A review of patient notes on our unit revealed 43% reported difficulties associated with constipation...
- Polymicrobial peritonitis in peritoneal dialysis patients in Australia: predictors, treatment, and outcomesKatherine Barraclough
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Am J Kidney Dis 55:121-31. 2010The study aim was to examine the frequency, predictors, treatment, and clinical outcomes of peritoneal dialysis-associated polymicrobial peritonitis.
- Correlations of lean body mass with nutritional indicators and mortality in patients on peritoneal dialysisJ Dong
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, PR China
Kidney Int 73:334-40. 2008..kinetics, anthropometry, and biometric impedance in 210 incident Chinese patients on continuous ambulatory peritoneal dialysis. The study was started in the third month of dialysis and the patients were followed for an average of 29 ..
- A study of the clinical and biochemical profile of peritoneal dialysis fluid low in glucose degradation productsKar Neng Lai
Department of Medicine, The University of Hong Kong, Hong Kong SAR, PR China
Perit Dial Int 32:280-91. 2012Although peritoneal dialysis (PD) is a widely accepted form of renal replacement therapy, concerns remain regarding the bioincompatible nature of standard PD fluid (PDF)...
- Staphylococcus aureus peritonitis complicates peritoneal dialysis: review of 245 consecutive casesCheuk Chun Szeto
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Clin J Am Soc Nephrol 2:245-51. 2007Peritonitis that is caused by Staphylococcus aureus is a serious complication in peritoneal dialysis (PD), but the clinical course of PD-related S. aureus peritonitis remains unclear. All of the S...
- Selection bias explains apparent differential mortality between dialysis modalitiesRobert R Quinn
University of Calgary, Foothills Medical Centre, Calgary, Alberta, T2N 2T9 Canada
J Am Soc Nephrol 22:1534-42. 2011The relative risk of death for patients treated with peritoneal dialysis compared with those treated with hemodialysis appears to change with duration of dialysis therapy...
- Relationship between dialysis modality and mortalityStephen P McDonald
Renal Unit, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South SA 5011, Australia
J Am Soc Nephrol 20:155-63. 2009Mortality differences between peritoneal dialysis (PD) and hemodialysis (HD) are widely debated...
- Association of dialysis modality and cardiovascular mortality in incident dialysis patientsDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia
Clin J Am Soc Nephrol 4:1620-8. 2009The aim of the investigation presented here was to compare the rates, causes, and timing of cardiovascular (CV) death in incident peritoneal dialysis (PD) and hemodialysis (HD) patients.
- Predictors, treatment, and outcomes of non-Pseudomonas Gram-negative peritonitisElizabeth M Jarvis
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia
Kidney Int 78:408-14. 2010Non-Pseudomonas Gram-negative (NPGN) peritonitis is a frequent, serious complication of peritoneal dialysis; however, previous reports have been limited to small, single-center studies...
- Three purse-string sutures allow immediate start of peritoneal dialysis with a low incidence of leakageBernd G Stegmayr
Department of Internal Medicine, University Hospital, Umea, Sweden
Semin Dial 16:346-8. 2003b>Peritoneal dialysis (PD) depends to a great extent on a well-functioning dialysis catheter...
- Encapsulating peritoneal sclerosis in Japan: a prospective, controlled, multicenter studyHideki Kawanishi
Tsuchiya General Hospital, Hiroshima, Japan
Am J Kidney Dis 44:729-37. 2004Encapsulating peritoneal sclerosis (EPS) is recognized as a rare but serious complication of peritoneal dialysis (PD). The aim of this study was to determine the incidence, clinical features, and mortality rate of EPS.
- Can a reduction in extracellular fluid volume result in increased serum albumin in peritoneal dialysis patients?Colin H Jones
Department of Renal Medicine, York District Hospital, York, United Kingdom
Am J Kidney Dis 39:872-5. 2002..We investigated whether decreasing dry weight increases serum albumin in peritoneal dialysis patients...
- Biocompatibility of a bicarbonate-buffered amino-acid-based solution for peritoneal dialysisThorsten O Bender
Department of Nephrology and Medical Intensive Care, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
Pediatr Nephrol 23:1537-43. 2008Amino-acid-based peritoneal dialysis (PD) fluids have been developed to improve the nutritional status of PD patients...
- Fatigue in chronic peritoneal dialysis patientsShahrzad Ossareh
Peritoneal Dialysis Program, Toronto Western Hospital, Division of Nephrology, University of Toronto, Canada
Int Urol Nephrol 35:535-41. 2003..Anemia seems to be the most important factor associated with fatigue. Dialysis adequacy and nutritional state did not show any correlation with the frequency of fatigue in our study...
- Use of ACE inhibitors or angiotensin receptor blockers and survival in patients on peritoneal dialysisWei Fang
University Health Network, University of Toronto, Toronto, Ontario, Canada
Nephrol Dial Transplant 23:3704-10. 2008..However, their effect on survival has not been studied in peritoneal dialysis (PD) patients...
- Efficacy of intravenous methoxy polyethylene glycol-epoetin beta administered every 2 weeks compared with epoetin administered 3 times weekly in patients treated by hemodialysis or peritoneal dialysis: a randomized trialMarian Klinger
Department of Nephrology and Transplantation Medicine, Medical University, Wroclaw, Poland
Am J Kidney Dis 50:989-1000. 2007..We examined its efficacy for Hb level correction when administered once every 2 weeks in erythropoiesis-stimulating agent-naive dialysis patients...
- Factors associated with blood concentrations of indoxyl sulfate and p-cresol in patients undergoing peritoneal dialysisChien Te Lee
Division of Nephrology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan
Perit Dial Int 30:456-63. 2010..Factors relevant to indoxyl sulfate and p-cresol levels in peritoneal dialysis (PD) patients have rarely been investigated...
- The efficacy of silver-ion implanted catheters in reducing peritoneal dialysis-related infectionsJohn H Crabtree
Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, Bellflower, California 90706, USA
Perit Dial Int 23:368-74. 2003..Dialysis-related infections are the commonest cause of catheter loss and transfer to hemodialysis. Surface modifications of the catheter that reduce infections are of major importance...
- Induction of mesothelial HSP-72 upon in vivo exposure to peritoneal dialysis fluidKlaus Arbeiter
Vienna School of Medicine
Perit Dial Int 23:499-501. 2003
- Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically activeTakashi Shimada
Endocrine Unit, Thier 10, 50 Blossum Street, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 95:578-85. 2010..Design: Biologically active FGF23 in plasma from CKD patients treated by peritoneal dialysis was quantified using a cell-based Egr-1 reporter assay; bioactive FGF23 levels were compared with those ..
- Epidemiology of peritoneal dialysis: a story of believers and nonbelieversNorbert Lameire
Renal Division, University Hospital, 185 De Pintelaan, 9000 Gent, Belgium
Nat Rev Nephrol 6:75-82. 2010..In this Review, we compare the epidemiology of peritoneal dialysis with that of hemodialysis and describe some of the major differences in the global utilization of the two ..
- Analysis of depression and its effect on outcome among adult Indian peritoneal dialysis patientsSandeep Mahajan
Department of Nephrology, All India Institute of Medical Sciences, Delhi, India
Perit Dial Int 27:94-6. 2007
- Biocompatible peritoneal dialysis solutions: do we have one?Kunal Chaudhary
Division of Nephrology and Hypertension, University of Missouri Columbia School of Medicine, Harry S Truman VA Medical Center, 800 Hospital Drive, Columbia, MO 65201, USA
Clin J Am Soc Nephrol 5:723-32. 2010Clinical experience and literature evidence suggest that peritoneal dialysis (PD) is a safe and effective treatment in short term (3 to 5 years) for stage 5 chronic kidney disease patients...
- Does diabetes mellitus predispose to increased fluid overload in peritoneal dialysis patients?Andrew Davenport
University College London Center for Nephrology, Royal Free and University College Medical School, London, UK
Nephron Clin Pract 114:c60-6. 2010Diabetic peritoneal dialysis patients have been reported to have faster peritoneal solute transport and may be at risk of reduced ultrafiltration volumes, leading to fluid overload.
- The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in JapanIchiro Hirahara
Division of Nephrology, Department of Medicine, Jichi Medical School, 3311 1 Yakushiji, Shimotsuke City, Tochigi 329 0498, Japan
Nephrol Dial Transplant 22:560-7. 2007Long-term peritoneal dialysis (PD) leads to peritoneal injury. At worst, peritoneal injury leads to encapsulating peritoneal sclerosis (EPS), which is a serious complication of PD. The mortality rate of EPS is extremely high...
- Change in bacterial aetiology of peritoneal dialysis-related peritonitis over 10 years: experience from a centre in South-East AsiaC C Szeto
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Clin Microbiol Infect 11:837-9. 2005This study reviewed 1787 episodes of peritoneal dialysis (PD)-related peritonitis in 544 patients between 1994 and 2003. The overall rate of peritonitis was 0.68 episodes/year of PD, but decreased from 1.10 to 0...
- Reduction of perlecan synthesis and induction of TGF-beta1 in human peritoneal mesothelial cells due to high dialysate glucose concentration: implication in peritoneal dialysisSusan Yung
Division of Nephrology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
J Am Soc Nephrol 15:1178-88. 2004..its selective permeability, thereby impairing the peritoneal transport properties in patients on long-term peritoneal dialysis (PD)...
- An all titanium transcutaneous access device (TAD) for peritoneal dialysisRobert Whalen; Fiscal Year: 2007Chronic transcutaneous access is needed for peritoneal dialysis (PD) and new emerging medical therapies...
- REGULATION OF BONE FORMATION IN RENAL OSTEODYSTROPHYIsidro B Salusky; Fiscal Year: 2004..on bone formation and parathyroid gland function in children with bone biopsy proven 2-HPT and treated with peritoneal dialysis. Also the response to these two vitamin D sterols will be assessed in patients given calcium carbonate or a ..
- Effects of Hyaluronan on Interstitial ConvectionMICHAEL FLESSNER; Fiscal Year: 2007..to quantify solute diffusion and convection in the subperitoneal muscle of anesthetized rats during peritoneal dialysis. The in vivo model permits control of the tissue pressure forces and measurement of the pressure profile ..
- Dynamics of Peritoneal Dialysis Associated PeritonitisJohn Hotchkiss; Fiscal Year: 2004..on interactions between dynamics of bacterial growth and optimal bacterial clearance in the setting of peritoneal dialysis associated peritonitis (PDAP)...
- Stent Lock Mechanism for Transcutaneous CathetersNICHOLAS VITALE; Fiscal Year: 2005b>Peritoneal dialysis, intravascular access for chemotherapy, transcutaneous intrathoracic access of cardiac power lines, and suprapubic bladder drainage are among the clinical applications where transcutaneous catheters are routinely used ..
- CALCITRIOL THERAPY ON DIALYZED CHILDRENISIDRO SALUSKY; Fiscal Year: 1993..calcitriol will be performed in pediatric patients with secondary hyperparathyroidism and treated with peritoneal dialysis. Therapeutic responses will be judged by changes in biochemical indices of parathyroid hormone secretion ..
- ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASEAlan Christensen; Fiscal Year: 2003..g., continuous ambulatory peritoneal dialysis) but poorer adherence when receiving staff administered dialysis (e.g., center hemodialysis)...
- Assessing Functional Outcomes in Adolescent with ESRDSusan Furth; Fiscal Year: 2002..quality of life (HRQL) for pediatric patients with chronic renal failure or ESRD treated with hemodialysis, peritoneal dialysis or transplant. Resources provided by the RO3 award will allow Dr...
- PERITONEAL DELIVERY OF ANTINEOPLASTIC MACROMOLECULESMICHAEL FLESSNER; Fiscal Year: 2004..of the MAb to tumor, a human xenograft will be transplanted into the abdominal wall of athymic rats, and peritoneal dialysis will be used to deliver MAb. The tumor position permits control of the intraperitoneal (i.p...
- S.T.R.A.P Sonos Transportable Renal Application ProductMartin Roberts; Fiscal Year: 2005..5 billion. Hemodialysis requires patient treatment 3 times a week for 3-4 hours. Peritoneal dialysis is an option utilized by less than 10% of patients requiring manual exchange of 2 liters of dialysate every ..
- DIURNAL AND PULSATILE PTH SECRETION IN RENAL FAILUREWilliam Goodman; Fiscal Year: 2001..with secondary hyperparathyroidism will also be evaluated, and the respective roles of hemodialysis and peritoneal dialysis as separate modifiers of diurnal and pulsatile PTH secretion in end-stage renal disease will be examined...
- Acute Renal Failure Mediated Lung InjurySarah Faubel; Fiscal Year: 2010..if the uremic factors that stimulate IL-6 production in AKI may be removed by dialysis, the effect of acute peritoneal dialysis on IL-6 production and serum IL-6 will be determined...
- Acute Renal Failure Mediated Lung InjurySarah Faubel; Fiscal Year: 2009..if the uremic factors that stimulate IL-6 production in AKI may be removed by dialysis, the effect of acute peritoneal dialysis on IL-6 production and serum IL-6 will be determined...
- Dietary Adherence Enhancement in Peritoneal DialysisMARY SEVICK; Fiscal Year: 2007..study will pilot test an intervention! based on self-efficacy theory, to improve adherence to the peritoneal dialysis dietary regimen...
- Patient-Oriented Research in Kidney DiseaseNeil Powe; Fiscal Year: 2007..This is a national prospective cohort study comparing treatment and outcomes in hemodialysis and peritoneal dialysis patients...
- LONG-TERM PERCUTANEOUS ACCESS DEVICE FOR HOME THERAPIESLUDMILA BERNSTAM; Fiscal Year: 2005..devices for treatment of chronic heart failure, total parenteral nutrition, drug delivery, and ambulatory peritoneal dialysis. The PAD is pre-seeded with autologous fibroblasts derived from a small sample of the recipient's skin...