renal dialysis

Summary

Summary: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.

Top Publications

  1. ncbi Mineral metabolism, mortality, and morbidity in maintenance hemodialysis
    Geoffrey A Block
    Denver Nephrology Associates, Denver Colorado, USA
    J Am Soc Nephrol 15:2208-18. 2004
  2. ncbi Rosuvastatin and cardiovascular events in patients undergoing hemodialysis
    Bengt C Fellström
    Department of Medical Science, Renal Unit, University Hospital, SE 751 85, Uppsala, Sweden
    N Engl J Med 360:1395-407. 2009
  3. ncbi Chronic kidney disease and the risk for cardiovascular disease, renal replacement, and death in the United States Medicare population, 1998 to 1999
    Robert N Foley
    United States Renal Data System Coordinating Center, 914 South 8th Street, Suite D 253, Minneapolis, MN 55404, USA
    J Am Soc Nephrol 16:489-95. 2005
  4. ncbi Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patients
    W N Suki
    Renal Section, Department of Medicine, The Kidney Institute, Baylor College of Medicine, Houston, Texas 77054, USA
    Kidney Int 72:1130-7. 2007
  5. ncbi Neutrophil gelatinase-associated lipocalin in dialyzed patients is related to residual renal function, type of renal replacement therapy and inflammation
    Jolanta Malyszko
    Department of Nephrology, Medical University, Bialystok, Poland
    Kidney Blood Press Res 32:464-9. 2009
  6. ncbi The progression of coronary artery calcification in predialysis patients on calcium carbonate or sevelamer
    D Russo
    Department of Nephrology, University Federico II, Naples, Italy
    Kidney Int 72:1255-61. 2007
  7. ncbi Predictors of loss of residual renal function among new dialysis patients
    L M Moist
    Department of Medicine, University of Western Ontario, London, Canada
    J Am Soc Nephrol 11:556-64. 2000
  8. ncbi Association of serum prealbumin and its changes over time with clinical outcomes and survival in patients receiving hemodialysis
    Mehdi Rambod
    Harold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, General Clinical Research Center, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Am J Clin Nutr 88:1485-94. 2008
  9. ncbi The quality of life and cost utility of home nocturnal and conventional in-center hemodialysis
    Philip A McFarlane
    Department of Medicine, Home Dialysis Clinic, Inner City Health Research Unit, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Kidney Int 64:1004-11. 2003
  10. ncbi Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients
    K Sharma
    Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Kidney Int 51:1980-5. 1997

Research Grants

  1. PROTAMINE FILTER FOR EXTRACORPOREAL HEPARIN REMOVAL
    Victor Yang; Fiscal Year: 1993
  2. ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASE
    Alan Christensen; Fiscal Year: 2003
  3. Novel Assay for Ethylene Glycol Toxicity
    HANS KLOEPFER; Fiscal Year: 2002
  4. Dialysis Facility Management
    Eric Eisenstein; Fiscal Year: 2003
  5. FUNCTION OF PLATELETS AND COAGULATION FACTORS
    PHILIP MAJERUS; Fiscal Year: 1980
  6. Noninvasive Raman Monitoring of Urea During Hemodialysis
    M Womble; Fiscal Year: 2004
  7. Rapid assessment of vascular grafts patency
    Hansen Mansy; Fiscal Year: 2007
  8. Measuring Intra/Extracellular Volume and Hemodynamics
    Leslie Montgomery; Fiscal Year: 2007
  9. Pathobiology of Kidney Disease: Role of Iron
    Rajiv Agarwal; Fiscal Year: 2007
  10. Hypertension in Hemodialysis Patients
    Rajiv Agarwal; Fiscal Year: 2007

Detail Information

Publications251 found, 100 shown here

  1. ncbi Mineral metabolism, mortality, and morbidity in maintenance hemodialysis
    Geoffrey A Block
    Denver Nephrology Associates, Denver Colorado, USA
    J Am Soc Nephrol 15:2208-18. 2004
    ..Disorders of mineral metabolism are independently associated with mortality and morbidity associated with cardiovascular disease and fracture in hemodialysis patients...
  2. ncbi Rosuvastatin and cardiovascular events in patients undergoing hemodialysis
    Bengt C Fellström
    Department of Medical Science, Renal Unit, University Hospital, SE 751 85, Uppsala, Sweden
    N Engl J Med 360:1395-407. 2009
    ..Statins reduce the incidence of cardiovascular events in patients at high cardiovascular risk. However, a benefit of statins in such patients who are undergoing hemodialysis has not been proved...
  3. ncbi Chronic kidney disease and the risk for cardiovascular disease, renal replacement, and death in the United States Medicare population, 1998 to 1999
    Robert N Foley
    United States Renal Data System Coordinating Center, 914 South 8th Street, Suite D 253, Minneapolis, MN 55404, USA
    J Am Soc Nephrol 16:489-95. 2005
    ..On an absolute basis, however, the high death rates of patients with CKD may reflect accelerated rates of atherosclerotic vascular disease and congestive heart failure...
  4. ncbi Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patients
    W N Suki
    Renal Section, Department of Medicine, The Kidney Institute, Baylor College of Medicine, Houston, Texas 77054, USA
    Kidney Int 72:1130-7. 2007
    ..There was a suggestion that sevelamer was associated with lower overall, but not cardiovascular-linked, mortality in older patients. We suggest that further research is needed to confirm these findings...
  5. ncbi Neutrophil gelatinase-associated lipocalin in dialyzed patients is related to residual renal function, type of renal replacement therapy and inflammation
    Jolanta Malyszko
    Department of Nephrology, Medical University, Bialystok, Poland
    Kidney Blood Press Res 32:464-9. 2009
    ..A cross-sectional study was performed to assess NGAL in serum, urine and ultrafiltrate in relation to the type of renal replacement therapy and NGAL correlations with renal function and markers of inflammation...
  6. ncbi The progression of coronary artery calcification in predialysis patients on calcium carbonate or sevelamer
    D Russo
    Department of Nephrology, University Federico II, Naples, Italy
    Kidney Int 72:1255-61. 2007
    ..Our study shows that sevelamer treatment should not be restricted to dialysis patients; however, a larger study should be undertaken to confirm these results...
  7. ncbi Predictors of loss of residual renal function among new dialysis patients
    L M Moist
    Department of Medicine, University of Western Ontario, London, Canada
    J Am Soc Nephrol 11:556-64. 2000
    ..The observations of demographic groups at risk and potentially modifiable factors and therapies have generated testable hypotheses regarding therapies that may preserve RRF among end-stage renal disease patients...
  8. ncbi Association of serum prealbumin and its changes over time with clinical outcomes and survival in patients receiving hemodialysis
    Mehdi Rambod
    Harold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, General Clinical Research Center, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Am J Clin Nutr 88:1485-94. 2008
    ..In patients receiving maintenance hemodialysis (MHD), a low serum prealbumin is an indicator of protein-energy wasting...
  9. ncbi The quality of life and cost utility of home nocturnal and conventional in-center hemodialysis
    Philip A McFarlane
    Department of Medicine, Home Dialysis Clinic, Inner City Health Research Unit, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Kidney Int 64:1004-11. 2003
    ..We hypothesized that individuals performing home nocturnal hemodialysis would have a higher quality of life and superior cost utility than in-center hemodialysis patients...
  10. ncbi Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients
    K Sharma
    Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Kidney Int 51:1980-5. 1997
    ..In addition, plasma leptin is not cleared by hemodialysis with a modified cellulose membrane. Additional studies are required to evaluate the role of leptin in mediating the anorexia of uremia...
  11. ncbi Serum matrix metalloproteinases MMP-2 and MMP-3 levels in dialysis patients vary independently of CRP and IL-6 levels
    Gloria A Preston
    Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Nephron 92:817-23. 2002
    ..Little is known as to whether CRP, cytokines, such as IL-6 and IL-1beta that stimulate the synthesis of CRP, or matrix metalloproteinases (MMPs) are markers of inflammation in patients on dialysis...
  12. ncbi Lipoprotein metabolism and lipid management in chronic kidney disease
    Bonnie C H Kwan
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    J Am Soc Nephrol 18:1246-61. 2007
  13. ncbi Efficacy and tolerability of sevelamer carbonate in hyperphosphatemic patients who have chronic kidney disease and are not on dialysis
    Markus Ketteler
    Nephrologische Klinik, Klinikum Coburg gGmbH, Ketschendorfer Strasse 33, 96450 Coburg, Germany
    Clin J Am Soc Nephrol 3:1125-30. 2008
    ..This study investigated the ability of sevelamer carbonate to control serum phosphorous in hyperphosphatemic patients who had chronic kidney disease and were not on dialysis...
  14. ncbi Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis
    Christoph Wanner
    Division of Nephrology, Department of Medicine, University of Wurzburg, Wurzburg, Germany
    N Engl J Med 353:238-48. 2005
    ..However, the benefit of statins in such patients receiving hemodialysis, who are at high risk for cardiovascular disease and death, has not been examined...
  15. ncbi Association between cholesterol level and mortality in dialysis patients: role of inflammation and malnutrition
    Yongmei Liu
    Johns Hopkins University, Baltimore, MD 21205, USA
    JAMA 291:451-9. 2004
    ..These findings support treatment of hypercholesterolemia in this population...
  16. ncbi The HSP72 stress response of monocytes from patients on haemodialysis is impaired
    Stefan Reuter
    Department of Medicine D, University of Munster, Germany
    Nephrol Dial Transplant 24:2838-46. 2009
    ..Renal insufficiency-related alteration of microbicidal and tumoricidal functions of Mphi, major effectors of the immune system, might promote these diseases...
  17. ncbi The impact of dialysis modality on serum heat shock proteins in children and young adults with chronic kidney disease
    Kinga Musiał
    Department of Pediatric Nephrology, Wrocław Medical University, Wrocław, Poland
    Kidney Blood Press Res 32:366-72. 2009
    ..The aim of the study was to evaluate the serum HSP, their connections with dialysis modality and their possible role as markers of atherosclerosis...
  18. ncbi Glycemic control and cardiovascular events in diabetic hemodialysis patients
    Christiane Drechsler
    Department of Medicine, Division of Nephrology, University Hospital, Oberdürrbacherstrasse 6, D 97080 Wurzburg, Germany
    Circulation 120:2421-8. 2009
    ..Poor glycemic control is associated with cardiovascular comorbidities in the general population. This study investigated the impact of glycemic control on cardiac and vascular outcomes in diabetic hemodialysis patients...
  19. ncbi Sex-specific association of time-varying haemoglobin values with mortality in incident dialysis patients
    Gisela Sturm
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, Innsbruck, Austria
    Nephrol Dial Transplant 25:2715-22. 2010
    ..Previous studies in dialysis patients showed an association between haemoglobin levels and all-cause mortality, however, without addressing sex differences...
  20. ncbi Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients
    Eric D Weinhandl
    Chronic Disease Research Group, Minneapolis, MN 55404, USA
    J Am Soc Nephrol 21:499-506. 2010
    ..These data suggest that increased use of peritoneal dialysis may benefit incident ESRD patients...
  21. ncbi Impact of haemoglobin and erythropoietin dose changes on mortality: a secondary analysis of results from a randomized anaemia management trial
    Joanne H Lau
    Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Canada
    Nephrol Dial Transplant 25:4002-9. 2010
    ..To date, no study has evaluated the impact of Hgb variability on mortality in the setting of a uniform Hgb target and erythropoiesis-stimulating agents (ESA) dosing strategy...
  22. ncbi The views of patients and carers in treatment decision making for chronic kidney disease: systematic review and thematic synthesis of qualitative studies
    R L Morton
    Sydney School of Public Health, University of Sydney, Sydney, NSW 2006, Australia
    BMJ 340:c112. 2010
    ..To synthesise the views of patients and carers in decision making regarding treatment for chronic kidney disease, and to determine which factors influence those decisions...
  23. ncbi A systematic review of the effect of nocturnal hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life
    Michael Walsh
    Department of Medicine, University of Calgary, Alberta, Canada
    Kidney Int 67:1500-8. 2005
    ..Before significant resources are invested in initiating nocturnal hemodialysis programs, further data on mortality and cardiovascular morbidity, preferably from randomized clinical trials, are required...
  24. ncbi Assessment and clinical aspects of health-related quality of life in dialysis patients and patients with chronic kidney disease
    Stig Molsted
    Department of Nephrology, Hilleroed Hospital, Hilleroed, Denmark
    Nephron Clin Pract 106:c24-33. 2007
    ....
  25. ncbi Association of bone activity, calcium load, aortic stiffness, and calcifications in ESRD
    Gerard M London
    Service de Nephrologie, Centre Hospitalier Manhes, Fleury Merogis, France
    J Am Soc Nephrol 19:1827-35. 2008
    ..Independent of any other factor, including dosage of calcium-containing phosphate binders, adynamic bone was associated with greater aortic stiffening, suggesting cross-talk between the bone and arterial walls...
  26. ncbi Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    David A Goodkin
    Amgen Inc, Thousand Oaks, California, USA
    J Am Soc Nephrol 14:3270-7. 2003
    ..Adjustments for the observed variability will allow study of association between practice patterns and outcomes...
  27. ncbi Knowledge of dietary restrictions and the medical consequences of noncompliance by patients on hemodialysis are not predictive of dietary compliance
    Claire Louise Durose
    FOAD Centre, University of Southampton, School of Medicine, Princess Anne Hospital, United Kingdom
    J Am Diet Assoc 104:35-41. 2004
    ..Instead of the more traditional approach of information-giving, effective educational methods that focus on motivating patients to comply with dietary restrictions are needed to improve compliance...
  28. ncbi Impact of kidney bone disease and its management on survival of patients on dialysis
    Grace H Lee
    Department of Pharmacy, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    J Ren Nutr 17:38-44. 2007
    ..Because these associations may be secondary to bias by indication, randomized clinical trials are necessary to verify the findings of this and similar observational studies...
  29. ncbi Health-related quality of life as a predictor of mortality and hospitalization: the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    Donna L Mapes
    Amgen, Inc, Thousand Oaks, California, USA
    Kidney Int 64:339-49. 2003
    ..More research is needed to assess whether interventions to improve quality of life lower these risks among hemodialysis patients...
  30. ncbi Calcium, phosphate, and parathyroid hormone levels in combination and as a function of dialysis duration predict mortality: evidence for the complexity of the association between mineral metabolism and outcomes
    Lesley A Stevens
    Division of Nephrology, New England Medical Centre, Boston, Massachusetts, USA
    J Am Soc Nephrol 15:770-9. 2004
    ..In so doing, the complex interaction of time and MM can begin to be understand. Further exploration is required...
  31. ncbi Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients
    K Kalantar-Zadeh
    Division of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    Kidney Int 70:771-80. 2006
    ....
  32. ncbi Optimization of dialysate sodium in sodium profiling haemodialysis
    Moon Jae Kim
    Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University College of Medicine, Inchon City, Korea
    Nephrology (Carlton) 8:S16-22. 2003
    ..In the future, dialysate sodium should be optimized based on the exact prediction of the postdialysis plasma sodium levels...
  33. ncbi A randomized, double-blind, placebo-controlled trial of niacinamide for reduction of phosphorus in hemodialysis patients
    Steven C Cheng
    Division of Nephrology, Washington University School of Medicine, 660 S Euclid Avenue, Campus Box 8129, St Louis, MO 63110, USA
    Clin J Am Soc Nephrol 3:1131-8. 2008
    ..A prospective, randomized, double-blind, placebo-controlled crossover trial was performed for assessment of the safety and efficacy of niacinamide...
  34. ncbi Comparison of glycated albumin and hemoglobin A(1c) levels in diabetic subjects on hemodialysis
    T P Peacock
    Section of Nephrology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Kidney Int 73:1062-8. 2008
    ..Our results show that in diabetic hemodialysis patients, hemoglobin A(1c) levels significantly underestimate glycemic control while those of glycated albumin more accurately reflect this control...
  35. ncbi Hemodialysis clinical practice guidelines for the Canadian Society of Nephrology
    Kailash Jindal
    J Am Soc Nephrol 17:S1-27. 2006
  36. ncbi The kind of vascular access influences the baseline inflammatory status and epoetin response in chronic hemodialysis patients
    Ezio Movilli
    Chair and Division of Nephrology, Spedali Civili and University of Brescia, University of Brescia, Brescia, Italy
    Blood Purif 24:387-93. 2006
    ....
  37. ncbi Plasma aluminium: a redundant test for patients on dialysis?
    P M Gault
    Department of Clinical Biochemistry, Leeds Teaching Hospitals, Britannia House, Morley, Leeds LS27 0DQ, UK
    Ann Clin Biochem 42:51-4. 2005
    Aluminium toxicity as a cause of dementia, osteodystrophy and anaemia in patients receiving renal dialysis was first described in the 1970s and led to the regular monitoring of aluminium in plasma and dialysate water...
  38. ncbi Predialysis psychoeducational intervention extends survival in CKD: a 20-year follow-up
    Gerald M Devins
    Behavioral Sciences and Health Research Division, Toronto General Research Institute, Toronto, Canada
    Am J Kidney Dis 46:1088-98. 2005
    ..The present research examines long-term survival after predialysis psychoeducational intervention. In addition, we examined whether survival differed because of early (ie, > or = 3 months) versus late referral to nephrology...
  39. ncbi Uremic malnutrition is a predictor of death independent of inflammatory status
    Lara B Pupim
    Division of Nephrology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2372, USA
    Kidney Int 66:2054-60. 2004
    ..Prevention of, and timely intervention to treat uremic malnutrition by suitable means are necessary independent of the presence and/or therapy of inflammation in terms of improving clinical outcomes in CHD patients...
  40. ncbi Mortality among hemodialysis patients in Europe, Japan, and the United States: case-mix effects
    David A Goodkin
    University Renal Research and Education Association, Ann Arbor, MI 48103, USA
    Am J Kidney Dis 44:16-21. 2004
    ....
  41. ncbi Longitudinal study of nutritional status, body composition, and physical function in hemodialysis patients
    Kirsten L Johansen
    Division of Nephrology, San Francisco Veterans Affairs Medical Center, CA 94121, USA
    Am J Clin Nutr 77:842-6. 2003
    ..Cross-sectional studies have shown an association between the duration (y) of dialysis and nutritional status, providing evidence of wasting...
  42. ncbi Non-dipping is a potent predictor of cardiovascular mortality and is associated with autonomic dysfunction in haemodialysis patients
    Manchang Liu
    Division of Clinical Immunology, Department of Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nephrol Dial Transplant 18:563-9. 2003
    ..CONCLUSIONS: The non-dipping phenomenon is closely related to a high incidence of CV diseases, a poor long-term survival and profound autonomic dysfunction. ABPM is useful in predicting long-term CV prognosis in HD patients...
  43. ncbi The low molecular weight apo(a) phenotype is an independent predictor for coronary artery disease in hemodialysis patients: a prospective follow-up
    F Kronenberg
    Institute of Medical Biology and Human Genetics, University of Innsbruck, Austria
    J Am Soc Nephrol 10:1027-36. 1999
    ..Apo(a) phenotyping might be helpful to identify hemodialysis patients at high risk for coronary artery disease...
  44. ncbi Optimization of epoetin therapy with intravenous iron therapy in hemodialysis patients
    A Besarab
    Department of Medicine, Henry Ford Hospital, Detroit, Michigan, USA
    J Am Soc Nephrol 11:530-8. 2000
    ..Reticulocyte hemoglobin content increased only in the study group from 28.5 to 30.1 pg. It is concluded that maintenance of TSAT between 30 and 50% reduces rhEPO requirements significantly over a 6-mo period...
  45. ncbi Long-term dialysis survivors: a transformational experience
    Roberta Braun Curtin
    Medical Education Institute, Inc, Madison, WI, USA
    Qual Health Res 12:609-24. 2002
    ....
  46. ncbi Prealbumin is as important as albumin in the nutritional assessment of hemodialysis patients
    G M Chertow
    Divisions of Nephrology, Moffitt Long Hospitals and UCSF Mt Zion Medical Center, and Departments of Medicine and Nutrition, University of California, San Francisco, California 94143 0532, USA
    Kidney Int 58:2512-7. 2000
    ..In this study, we aimed to determine the independent association of serum prealbumin with survival in hemodialysis patients, after adjusting for serum albumin and other indicators of protein energy nutritional status...
  47. ncbi Traditional cardiovascular disease risk factors in dialysis patients compared with the general population: the CHOICE Study
    J Craig Longenecker
    Johns Hopkins University School of Medicine, Suite 2 637, 2024 E Monument Street, Baltimore, MD 21205, USA
    J Am Soc Nephrol 13:1918-27. 2002
    ..In summary, many ASCVD risk factors are more prevalent in ESRD than in the general population and may explain some, but probably not all, of the increased ASCVD risk in ESRD...
  48. ncbi Changes in serum calcium, phosphate, and PTH and the risk of death in incident dialysis patients: a longitudinal study
    M L Melamed
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Kidney Int 70:351-7. 2006
    ..Promising new interventions need to be rigorously tested in clinical trials for their ability to achieve normalization of bone mineral parameters and reduce deaths of dialysis patients...
  49. ncbi Effect of angiotensin receptor blockers on cardiovascular events in patients undergoing hemodialysis: an open-label randomized controlled trial
    Hiromichi Suzuki
    Department of Nephrology, School of Medicine, Faculty of Medicine, Saitama Medical University, Saitama, Japan
    Am J Kidney Dis 52:501-6. 2008
    ..Although angiotensin receptor blockers (ARBs) reduce cardiovascular disease (CVD) events in patients with diabetes and chronic kidney disease, their effect in patients with kidney failure on HD therapy is not known...
  50. ncbi Randomized controlled trial on the efficacy and safety of atorvastatin in patients with type 2 diabetes on hemodialysis (4D study): demographic and baseline characteristics
    Christoph Wanner
    Division of Nephrology, University Clinic, Wurzburg, Germany
    Kidney Blood Press Res 27:259-66. 2004
    ..The results of the study will provide important information on the efficacy and safety of atorvastatin to support its use in patients with an impaired renal function who are at a high risk of vascular morbidity and mortality...
  51. ncbi Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    Francesca Tentori
    Arbor Research Collaborative for Health, University of Michigan, Ann Arbor, MI 48103, USA
    Am J Kidney Dis 52:519-30. 2008
    ....
  52. ncbi Mortality and technique failure in patients starting chronic peritoneal dialysis: results of The Netherlands Cooperative Study on the Adequacy of Dialysis. NECOSAD Study Group
    K J Jager
    Department of Nephrology, Academic Medical Center, University of Amsterdam, The Netherlands
    Kidney Int 55:1476-85. 1999
    ..The aim of this study was to determine the relative importance of baseline patient and treatment characteristics to mortality and technique failure in patients starting peritoneal dialysis...
  53. ncbi The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic peptide with mortality in an incident dialysis cohort
    Ghazaleh Gouya
    Department of Clinical Pharmacology, Medical University Vienna, Vienna, Austria
    PLoS ONE 6:e17803. 2011
    ..58, p = 0.001). In summary, among incident dialysis patients MR-proANP and MR-proADM were shown to be associated with all-cause and CV mortality, with the highest risk when both parameters were in the upper tertiles...
  54. ncbi Older patients undergoing dialysis treatment: cognitive functioning, depressive mood and health-related quality of life
    J Tyrrell
    Laboratoire de Psychologie Clinique et de Psychopathologie, , Grenoble
    Aging Ment Health 9:374-9. 2005
    ..The information obtained should assist staff as they reflect on individual cases where the benefits of continuing treatment are being examined...
  55. ncbi Do AV fistulas contribute to cardiac mortality in hemodialysis patients?
    Ralf Dikow
    Department of Internal Medicine, Ruperto Carola University, Heidelberg, Germany
    Semin Dial 15:14-7. 2002
    ..Fistula flow should be monitored (e.g., by duplex sonography) to guarantee adequate flow and permit preemptive intervention to avoid fistula thrombosis...
  56. ncbi Type of vascular access and survival among incident hemodialysis patients: the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study
    Brad C Astor
    Johns Hopkins Department of Epidemiology, Welch Center for Prevention, Epidemiology, and Clinical Research, The Johns Hopkins University, 2024 East Monument Street, Suite 2 600 Baltimore, Maryland 21205, USA
    J Am Soc Nephrol 16:1449-55. 2005
    ....
  57. ncbi Spectrum of acute renal failure in the intensive care unit: the PICARD experience
    Ravindra L Mehta
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, California, USA
    Kidney Int 66:1613-21. 2004
    ..There is wide variation across institutions in patient characteristics and practice patterns. These differences highlight the need for additional multicenter observational and interventional studies in ARF...
  58. ncbi Specific adsorption of some complement activation proteins to polysulfone dialysis membranes during hemodialysis
    Jan Mares
    Department of Internal Medicine I, Charles University Medical School and Teaching Hospital, Plzen, Czech Republic
    Kidney Int 76:404-13. 2009
    ..Our finding of a selective binding of ficolin-2 to polysulfone membranes suggests a possible role of the lectin complement pathway in blood-dialyser interactions...
  59. ncbi Glycemic control and the risk of death in 1,484 patients receiving maintenance hemodialysis
    Sabin Shurraw
    Division of Nephrology, University of Alberta, Edmonton, Alberta, Canada
    Am J Kidney Dis 55:875-84. 2010
    ..We aim to determine whether worse glycemic control, measured using serum glucose and hemoglobin A(1c) (HbA(1c)) levels, is independently associated with higher mortality in patients undergoing maintenance hemodialysis...
  60. ncbi Sleep disturbances in dialysis patients
    Kathy P Parker
    Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA
    Sleep Med Rev 7:131-43. 2003
    ....
  61. ncbi Validation of the kidney disease quality of life-short form: a cross-sectional study of a dialysis-targeted health measure in Singapore
    Veena D Joshi
    Singhealth Centre for Health Services Research, Singapore Health Services Pte Ltd, Singapore
    BMC Nephrol 11:36. 2010
    ..We aimed to determine the reliability and validity of the KDQOL-SF™ for haemodialysis patients in Singapore...
  62. ncbi The hemodynamic tolerability and feasibility of sustained low efficiency dialysis in the management of critically ill patients with acute kidney injury
    Heather E Fieghen
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    BMC Nephrol 11:32. 2010
    ..We also compared the feasibility of SLED administration with that of CRRT and intermittent hemodialysis (IHD)...
  63. ncbi Unusual vascular access for hemodialysis: transposed venae comitante of the brachial artery
    Hossam A Elwakeel
    Vascular Surgery Unit, Mansoura University Hospital, Mansoura, Egypt
    Ann Vasc Surg 21:560-3. 2007
    ..Brachial artery to its transposed venae comitante fistula is an alternative access which can be used as a tertiary autogenous access...
  64. ncbi Combination of duplex ultrasound-guided manual declotting and percutaneous transluminal angioplasty in thrombosed native dialysis fistulas
    Hsuan-Li Huang
    Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan
    Ren Fail 27:713-9. 2005
    ..It simplifies the interventional procedure, reduces cost and radiation exposure time, and extends life span of dialysis fistula with acceptable long-term patency rate...
  65. ncbi [Frequency and clinical implications of lupus anticoagulant in patients with terminal chronic renal failure in hemodialysis]
    Mary C Fernández-Abreu
    Servicio de Nefrologia, Hospital General del Sur Dr Pedro Iturbe, Venezuela
    Invest Clin 48:69-79. 2007
    ....
  66. ncbi Axillary loop grafts for hemodialysis access: midterm results from a single-center study
    Elixène Jean-Baptiste
    Service de Chirurgie Vasculaire, Hopital Saint Roch, University Hospital of Nice, 5 rue Pierre Devoluy, Nice, France
    J Vasc Surg 47:138-43. 2008
    ..This study reports our midterm results with arteriovenous axillary loop grafts (AVALG) and evaluates their role in construction of vascular access for patients on chronic hemodialysis...
  67. ncbi Neurologic and ischemic complications of upper extremity vascular access for dialysis
    A B Redfern
    Raymond M Curtis Hand Center, Union Memorial Hospital, Baltimore, MD, USA
    J Hand Surg Am 20:199-204. 1995
    ..Sixteen of the 22 patients had ligation or revision of the fistula. Five patients underwent amputations at the metacarpal or phalangeal level, and one patient underwent below-elbow amputation...
  68. ncbi The value of preoperative vascular imaging in the selection and success of hemodialysis access
    Feza Karakayali
    Department of General Surgery, Baskent University Faculty of Medicine, 06490 Ankara, Turkey
    Ann Vasc Surg 21:481-9. 2007
    ..In patients with end-stage renal disease, these interventions should lead to a decrease in morbidity and mortality and improved quality of life...
  69. ncbi Tunneled catheters in hemodialysis patients: reasons and subsequent outcomes
    Timmy Lee
    Division of Nephrology, University of Alabama, Birmingham, AL, USA
    Am J Kidney Dis 46:501-8. 2005
    ..In the interim, this patient population developed a high frequency of catheter-related bacteremia...
  70. ncbi Follow-up of polytetrafluoroethylene arteriovenous fistulae for haemodialysis
    B Modarai
    Department of Urology, Guy's and St. Thomas' Hospitals, Thomas Guy House, London, UK
    Int J Clin Pract 59:1005-7. 2005
    ..All options using autologous vein should be exhausted before considering prosthetic material...
  71. ncbi A single center experience in the use of polyurethaneurea arteriovenous grafts
    Dijana Jefic
    Department of Nephrology and Hypertension, St. John Hospital and Medical Center, Detroit, Michigan, USA
    Nephrol News Issues 19:44-7. 2005
    ..Decreased bleeding time with PUU grafts reduced aggregate blood exposure for patients and staff, lowering the risk of infection and anemia exacerbation and speeding time between treatments...
  72. ncbi [Analysis of the survival of permanent vascular access ports]
    J A Rodriguez
    Hospital General Universitario Vall d Hebron, Servicio de Nefrologia, Barcelona
    Nefrologia 21:260-73. 2001
    ....
  73. ncbi Relationship of preoperative venous and arterial imaging findings to outcomes of brachio-basilic transposition fistulae for hemodialysis: a prospective clinical study
    F Y Karakayali
    Baskent University Faculty of Medicine, Department of General Surgery, Ankara, Turkey
    Eur J Vasc Endovasc Surg 35:208-13. 2008
    ..To evaluate the maturation and patency of transposed brachio-basilic fistulae that had been chosen based on the results of preoperative imaging techniques...
  74. ncbi Non-surgical salvage of thrombosed arterio-venous fistulae: a case series and review of the literature
    Shahriar Moossavi
    Department of Internal Medicine, Wake Forsest University School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Semin Dial 20:459-64. 2007
    ..We conclude that interventional repairs should routinely be employed to salvage newly thrombosed AVF. The vast majority of these individuals can avoid receiving dialysis catheters or placement of a new dialysis vascular access...
  75. ncbi Single center review of femoral arteriovenous grafts for hemodialysis
    Michael J Englesbe
    Department of Surgery, Section of Transplantation, University of Michigan Health System, 2926 Taubman Center, 1500 E Medical Center Drive, Ann Arbor, Michigan, 48109 0331, USA
    World J Surg 30:171-5. 2006
    ..The National Kidney Foundation Practice Guidelines urge prompt removal of the catheter, but the guidelines do not specifically address the problem of patients whose only option is a femoral arteriovenous (AV) graft...
  76. ncbi Impact of obesity on arteriovenous fistula outcomes in dialysis patients
    M Kats
    Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Kidney Int 71:39-43. 2007
    ..93; 95% CI, 1.44-5.93; P=0.004). In conclusion, long-term fistula survival is worse in obese than non-obese patients, owing to a higher secondary failure rate...
  77. ncbi Effect of secondary interventions on patency of vascular access sites for hemodialysis
    F Karakayali
    Department of General Surgery, , Ankara, Turkey
    Eur J Vasc Endovasc Surg 32:701-9. 2006
    ..CONCLUSIONS: Frequent, regular follow-up of hemodialysis patients with vascular access sites is the best way to diagnose problems early and allow the best chance of long-term function...
  78. ncbi [Influence of the arterio-venous fistula on cardiovascular system in patients with particular cardiovascular risk]
    Magdalena Krajewska
    Akademia Medyczna we Wrocławiu, Katedra i Klinika Nefrologii i Medycyny Transplantacyjnej
    Pol Merkur Lekarski 21:145-6; discussion 147. 2006
    ..We conclude that impact of native arterio-venous fistula created on forearm on circulation in the group of elderly and diabetic patients is of the same magnitude as in the group of younger, non diabetic patients...
  79. ncbi Regarding "autogenous radial-cephalic or prosthetic brachial-antecubital forearm loop avf in patients with compromised vessels? A randomized multicenter study of the patency of primary hemodialysis access"
    Luc Turmel-Rodrigues
    J Vasc Surg 43:1315; author reply 1315-6. 2006
  80. ncbi Vascular access outcomes and medication use: a USRDS study
    Alexander S Yevzlin
    School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53713, USA
    Semin Dial 19:535-9. 2006
    ..Antiplatelet agents had a significant negative association with access patency in this cohort. In contrast to other published data, it was difficult to identify any beneficial effect of specific medications on access patency...
  81. ncbi Overutilization of central venous catheters in incident hemodialysis patients: reasons and potential resolution strategies
    Oliver Lenz
    Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Semin Dial 19:543-50. 2006
    ..The rate in eGFR decline might also be used to calculate the referral time adequate for fistula creation...
  82. ncbi Evaluation of the efficacy of the transposed upper arm arteriovenous fistula: a single institutional review of 190 basilic and cephalic vein transposition procedures
    Karen Woo
    Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Vasc Surg 46:94-99; discussion 100. 2007
    ..We then compared our tAVF patients with a cohort of upper arm arteriovenous grafts (AVG)...
  83. ncbi [Temporary catheter at dialysis onset: quality indicator of pre-dialysis care]
    F J Gomez-Campdera
    Servicio de Nefrología y Servicio de Cirugfa General, Hospital General Universitario Gregorio Maranon, Madrid
    Nefrologia 26:52-5. 2006
  84. ncbi Does the surgeon's experience impact on radiocephalic fistula patency rates?
    Nicholas Fassiadis
    South West Thames Surrey and Sussex Renal Transplant Unit, St George s Healthcare NHS Trust, London, United Kingdom
    Semin Dial 20:455-7. 2007
    ..These results suggest that the placement of a RCF should be performed by the most experienced member of a team dedicated to vascular access creation or at least under his supervision...
  85. ncbi Creation of permanent hemodialysis vascular access in patients with failed arteriovenous fistula
    Majid Moini
    Division of Vascular Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Saudi Med J 28:213-5. 2007
    ..To compare the patency rate and complications of arteriovenous fistula (AVF) with synthetic graft in patients with previous history of failed AVF...
  86. ncbi Ischemic steal syndrome: a case series and review of current management
    B P Mwipatayi
    Department of Vascular Surgery, Royal Perth Hospital, Perth, Western Australia
    Curr Surg 63:130-5. 2006
    ..The aim of this report is to review the experience of the authors on this complication and its management at Royal Perth Hospital...
  87. ncbi Obesity is not an obstacle for successful autogenous arteriovenous fistula creation in haemodialysis
    Waclaw Weyde
    Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Traugutta 57 59, 50 417 Wroclaw, Poland
    Nephrol Dial Transplant 23:1318-22. 2008
    ..Prosthetic angioaccess or catheters, when used in place of autogenous fistulas, increase thrombotic and infectious complications in these already challenged patients...
  88. ncbi Cutting balloon angioplasty for resistant venous stenoses of dialysis access: immediate and patency results
    Chih Cheng Wu
    Department of Medicine, Hsinchu General Hospital and School of Medicine, Yang Ming University, Taipei, Taiwan
    Catheter Cardiovasc Interv 71:250-4. 2008
    ..To evaluate the technical success, safety and patency of cutting balloon angioplasty for the treatment of resistant dialysis access stenoses...
  89. ncbi Frequency of critical stenosis in primary arteriovenous fistulae before hemodialysis access: should duplex ultrasound surveillance be the standard of care?
    Jennifer Grogan
    Department of Surgery, Vascular Section, University of Chicago, IL 60637, USA
    J Vasc Surg 41:1000-6. 2005
    ..We therefore investigated pAVFs with color duplex ultrasound (CDU) surveillance 4 to 12 weeks postoperatively to identify hemodynamically significant abnormalities that may contribute to pAVF failure...
  90. ncbi Endothelial nitric oxide synthase gene intron 4 (VNTR) polymorphism and vascular access graft thrombosis
    Ozgur Basaran
    Department of General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey
    J Invest Surg 20:49-53. 2007
    ..01, p = .01 and p = .04 for the three respective time points; Kaplan-Meier). ecNOS gene intron 4 VNTR polymorphism is linked with the pathogenesis of vascular access thrombosis in Turkish patients undergoing hemodialysis...
  91. ncbi Dialysis in adults in year 2000 in the Republic of Macedonia
    M H Polenakovic
    Department of Nephrology, Medical Faculty, Skopje, Republic of Macedonia
    Int J Artif Organs 25:386-90. 2002
    ..The survival rate of our patients treated with maintenance HD at 5 years was 58%. CAPD and particularly renal transplantation are to be further developed as alternative methods in treating terminal renal failure...
  92. ncbi Arteriovenous PTFE dialysis access in the lower extremity: a new approach
    Søren Flarup
    Department of Vascular Surgery, Aalborg University Hospital ASS, Denmark
    Ann Vasc Surg 17:581-4. 2003
    ..The procedure is easily and rapidly performed with good access, and the patient clientele is easily selected. The technique has not been described previously...
  93. ncbi Interventional techniques for malfunctioning accesses
    Joseph Shams
    Albert Einstein College of Medicine, Division of Vascular and Interventional Radiology, Beth Israel Medical Center, New York, N.Y, USA
    Contrib Nephrol 142:285-322. 2004
  94. ncbi The reverse J arteriovenous graft configuration for hemodialysis access: rationale, technique, and outcomes
    David L Cull
    Academic Department of Surgery, Greenville Hospital System University Medical Center, Greenville, South Carolina 29605, USA
    Am Surg 74:620-4; discussion 624-5. 2008
    ..Therefore, the reverse J configuration enhances the secondary patency of AV graft patency and AV access site longevity...
  95. ncbi Fistula elevation procedure: experience with 295 consecutive cases during a 7-year period
    Cathy M Bronder
    Academic Department of Surgery, Greenville Hospital System University Medical Center, Greenville, SC 29605, USA
    J Am Coll Surg 206:1076-81; discussion 1081-2. 2008
    ..The purpose of this study is to review use of FEP as an adjunct to fistula maturation...
  96. ncbi Long-term outcomes of brachiobasilic transposition fistula for haemodialysis
    A Taghizadeh
    Department of Urology and Nephrology, Guy's Hospital, Thomas Guy House, London, UK
    Eur J Vasc Endovasc Surg 26:670-2. 2003
    ..The complication rate, although high, is lower than that reported for PTFE grafts. Brachiobasilic fistulae should be used in preference to PTFE grafts for secondary access...
  97. ncbi Axillary artery to contralateral axillary vein graft fistula in chronic hemodialysis patients
    Feng-Rong Chuang
    Division of Nephrology, Department of Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan
    Ren Fail 25:871-8. 2003
    ..There is no AVF-related mortality in these patients. CONCLUSION: We conclude that axillary artery to contralateral axillary vein graft fistula may be a feasible alternative choice for chronic hemodialysis access...
  98. ncbi Complications of vascular access: results of a European multi centre study of the EDTNA/ERCA Research Board
    Monique M Elseviers
    EDTNA ERCA J 29:163-7. 2003
    ..Nurses have a key role in the prevention, manipulation and outcome of vascular access related complications...
  99. ncbi Hypercoagulable states and antithrombotic strategies in recurrent vascular access site thrombosis
    Susan I O'Shea
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Vasc Surg 38:541-8. 2003
    ..Prospective studies are needed to evaluate the role and safety of antithrombotic agents in improving vascular access graft patency...
  100. ncbi Failure of arteriovenous fistula maturation: an unintended consequence of exceeding dialysis outcome quality Initiative guidelines for hemodialysis access
    Sheela T Patel
    Vascular Surgery, University of Arizona Health Sciences Center, Tucson, AZ 85718, USA
    J Vasc Surg 38:439-45; discussion 445. 2003
    ..Our experience suggests that improved selection criteria based on findings at preoperative imaging are needed to further refine and optimize arteriovenous access surgery...
  101. ncbi Potential role of soluble CD40 in the humoral immune response impairment of uraemic patients
    Cécile Contin
    UMR CNRS 5540, Universite Bordeaux 2, Bordeaux, France
    Immunology 110:131-40. 2003
    ..Furthermore, the positive correlation we observed between the serum levels of sCD40 and the deficient response to hepatitis B vaccination in uraemic patients suggests that sCD40 also compromises the humoral response in vivo...

Research Grants90

  1. PROTAMINE FILTER FOR EXTRACORPOREAL HEPARIN REMOVAL
    Victor Yang; Fiscal Year: 1993
    Extracorporeal blood circulation (ECBC) has been employed in many important clinical situations such as renal dialysis and cardiopulmonary bypass. In the US alone, more than 15 million ECBC procedures are performed each year...
  2. ADHERENCE AND ADJUSTMENT IN END-STAGE RENAL DISEASE
    Alan Christensen; Fiscal Year: 2003
    ..characteristics that influence medical regimen adherence and emotional adjustment among patients treated with renal dialysis. This will be accomplished using a longitudinal study design that considers the effects of patient individual ..
  3. Novel Assay for Ethylene Glycol Toxicity
    HANS KLOEPFER; Fiscal Year: 2002
    ..late or unnecessary treatment; 3) cutting intensive care and hospital stay; 4) abating long term morbidity (renal dialysis)...
  4. Dialysis Facility Management
    Eric Eisenstein; Fiscal Year: 2003
    ..ESRD patients typically survive fewer than five years after beginning renal dialysis. During this time they average 1.9 hospitalizations per year, for a total of 14 days...
  5. FUNCTION OF PLATELETS AND COAGULATION FACTORS
    PHILIP MAJERUS; Fiscal Year: 1980
    ..We are also carrying out a randomized double bind study to determine the efficacy of 180mg aspirin per day in preventing shunt thrombosis in patients with chronic renal dialysis.
  6. Noninvasive Raman Monitoring of Urea During Hemodialysis
    M Womble; Fiscal Year: 2004
    ..be produced rapidly, if the Phase II work is successful, by the adaptation for the clinical setting of the Company's present R-2001 Raman module for attachment by fiberoptic probe to existing renal dialysis equipment.
  7. Rapid assessment of vascular grafts patency
    Hansen Mansy; Fiscal Year: 2007
    ..The Phase I effort focused on renal dialysis access grafts and fistulas, and showed high accuracy (p <...
  8. Measuring Intra/Extracellular Volume and Hemodynamics
    Leslie Montgomery; Fiscal Year: 2007
    ..of increased intracranial pressure following trauma, the treatment of disequilibrium and hypotension during renal dialysis, the monitoring of hydration state of premature infants, and the investigation and diagnosis of orthostatic ..
  9. Pathobiology of Kidney Disease: Role of Iron
    Rajiv Agarwal; Fiscal Year: 2007
    ..Novelty and Health Relatedness of the Project: This proposal will provide translational data on the role of intravenous iron to progression of kidney disease in patients with CKD. ..
  10. Hypertension in Hemodialysis Patients
    Rajiv Agarwal; Fiscal Year: 2007
    ..Evaluation of such strategies will improve BP control in hemodialysis patients and, in the long-term, provide cardiovascular protection. ..
  11. Hypertension in Hemodialysis Patients
    Rajiv Agarwal; Fiscal Year: 2010
    ..We hypothesize that that volume control can improve BP and antihypertensive therapy can regress left ventricular hypertrophy in long-term hemodialysis patients. ..
  12. Old Age, Life Extension, and Geriatrics
    SHARON KAUFMAN; Fiscal Year: 2005
    ..of life-extending medical procedures (cardiac bypass, angioplasty and stent; kidney and liver transplant; and renal dialysis) and how they each respond to those procedures; and second, to identify socio-cultural issues of relevance to ..
  13. Examining Racial and Cardiovascular Paradoxes in Chronic Kidney Disease
    Kamyar Kalantar Zadeh; Fiscal Year: 2010
    ..to developing new treatment targets beyond traditional (Framingham) CV risk factors to improve poor outcomes in these 2 patient populations and maybe in geriatric populations or those with chronic disease states and similar paradoxes ..
  14. Examining Racial and Cardiovascular Paradoxes in Chronic Kidney Disease
    Kamyar Kalantar Zadeh; Fiscal Year: 2009
    ..to developing new treatment targets beyond traditional (Framingham) CV risk factors to improve poor outcomes in these 2 patient populations and maybe in geriatric populations or those with chronic disease states and similar paradoxes ..
  15. Anti-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients
    Kamyar Kalantar Zadeh; Fiscal Year: 2007
    ....
  16. Examining Racial and Cardiovascular Paradoxes in Chronic Kidney Disease
    Kamyar Kalantar Zadeh; Fiscal Year: 2009
    ..to developing new treatment targets beyond traditional (Framingham) CV risk factors to improve poor outcomes in these 2 patient populations and maybe in geriatric populations or those with chronic disease states and similar paradoxes ..
  17. Nutritional/Inflammatory Evaluation of Dialysis Patients
    Kamyar Kalantar Zadeh; Fiscal Year: 2005
    ....
  18. The role of hypoxia in venous neointimal hyperplasia in hemodialysis grafts
    Sanjay Misra; Fiscal Year: 2010
    ..The long term goal of this current proposal and research program is to improve the care of patients with ESRD, the vast majority of who use long-term hemodialysis as their mode of renal replacement therapy. ..
  19. HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
    Michael Allon; Fiscal Year: 2007
    ..The primary endpoint will be fistula thrombosis within 6 weeks, and the secondary endpoint will be the ability to use the fistula successfully for dialysis within 6 months. ..
  20. Cognitive Behavioral Treatment of Depression in ESRD PAtients on Dialysis
    Daniel Cukor; Fiscal Year: 2007
    ..If it is proven to be beneficial, this targeted and brief intervention could be incorporated into standard of care for all depressed dialysis patients. ..
  21. Are Cardioprotective Medications Effective in ESRD?
    Theresa I Shireman; Fiscal Year: 2010
    ..This project will evaluate the effectiveness of cardioprotective medications in reducing cardiac deaths and hospitalizations in ESRD patients. ..
  22. Natural History of MYH9-Associated Nephropathy
    Barry Freedman; Fiscal Year: 2009
    ..This will benefit individuals at risk who could benefit from therapeutic intervention to alleviate disease at an earlier stage. The anticipated benefits to the population at large outweigh the minimal risk involved in the study. ..
  23. Genetic Analysis of African American Hypertensive End-Stage Renal Disease
    Barry Freedman; Fiscal Year: 2009
    ....
  24. EFFECTS OF ACID ON BONE
    David Bushinsky; Fiscal Year: 2004
    ..Our long term goal is to develop a model to describe how acidosis affects bone in order to devise therapy to preserve mineral while maintaining the H+ buffering properties of bone. ..
  25. MECHANISMS OF HYPOALBUMINEMIA IN ENDSTAGE RENAL DISEASE
    George Kaysen; Fiscal Year: 2001
    ..We will further establish the effect of KT/V, dialyzer permeability and reuse on changes in albumin, nutritional status and acute phase response. ..
  26. Pyrophosphate in vascular calcification of renal failure
    W O NEILL; Fiscal Year: 2007
    ..The results will establish a new paradigm for vascular calcification in renal failure and form the basis for important clinical trials in humans. ..
  27. Renal Volume Measurement to Detect Early Kidney Disease
    W O NEILL; Fiscal Year: 2004
    ..abstract_text> ..
  28. GRAFT REJECTION AND DIRECT VERSUS INDIRECT RECOGNITION
    Peter Heeger; Fiscal Year: 2007
    ..The findings derived from the work will define the role for indirectly primed CD8 T cells in allograft rejection and have the potential to guide future therapies aimed a prolonging graft survival. ..
  29. PREVENTION OF HEMODIALYSIS VASCULAR ACCESS STENOSIS
    Alfred Cheung; Fiscal Year: 2007
    ..It is highly likely that, within this 5-year proposal, the results of this project can be applied to pilot clinical studies. ..
  30. Novel Biomarkers in Cardiac Surgery to Detect Acute Kidney Injury
    Chirag Parikh; Fiscal Year: 2009
    ..The ultimate findings of this study will pave the way for larger multi-center studies of these biomarkers in other clinical conditions and for interventional clinical trials to prevent or to treat AKI. ..