hospitalization

Summary

Summary: The confinement of a patient in a hospital.

Top Publications

  1. ncbi Bronchiolitis-associated hospitalizations among US children, 1980-1996
    D K Shay
    Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 282:1440-6. 1999
  2. pmc Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection
    Ryan Zarychanski
    Department of Internal Medicine, University of Manitoba, CancerCare Manitoba, Winnipeg, Manitoba
    CMAJ 182:257-64. 2010
  3. pmc Risk factors for hospitalisation and poor outcome with pandemic A/H1N1 influenza: United Kingdom first wave (May-September 2009)
    J S Nguyen-Van-Tam
    Division of Epidemiology and Public Health, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
    Thorax 65:645-51. 2010
  4. ncbi Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    N Engl J Med 351:1296-305. 2004
  5. ncbi Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico
    Rogelio Perez-Padilla
    National Institute of Respiratory Diseases, Mexico City, Mexico
    N Engl J Med 361:680-9. 2009
  6. ncbi The burden of respiratory syncytial virus infection in young children
    Caroline Breese Hall
    Department of Pediatrics, The University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    N Engl J Med 360:588-98. 2009
  7. ncbi Critically Ill patients with 2009 influenza A(H1N1) in Mexico
    Guillermo Dominguez-Cherit
    Division of Pulmonary and Critical Care Dr Domínguez Cherit, Hospital Epidemiology Department, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    JAMA 302:1880-7. 2009
  8. ncbi Prevalence, expenditures, and complications of multiple chronic conditions in the elderly
    Jennifer L Wolff
    Department of Health Policy and Management, The Johns Hopkins University Bloomberg School of Public Health, 624 N Broadway, Room 304, Baltimore, MD 21205, USA
    Arch Intern Med 162:2269-76. 2002
  9. pmc Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases
    Francesca Dominici
    Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    JAMA 295:1127-34. 2006
  10. pmc Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
    Munir Pirmohamed
    Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GE
    BMJ 329:15-9. 2004

Detail Information

Publications295 found, 100 shown here

  1. ncbi Bronchiolitis-associated hospitalizations among US children, 1980-1996
    D K Shay
    Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 282:1440-6. 1999
    ..Few national estimates exist of the hospitalizations attributable to RSV, and recent advances in prophylaxis warrant an update of these estimates...
  2. pmc Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection
    Ryan Zarychanski
    Department of Internal Medicine, University of Manitoba, CancerCare Manitoba, Winnipeg, Manitoba
    CMAJ 182:257-64. 2010
    ..The objective of this study was to identify factors correlated with severity of disease in confirmed cases of pandemic H1N1 influenza...
  3. pmc Risk factors for hospitalisation and poor outcome with pandemic A/H1N1 influenza: United Kingdom first wave (May-September 2009)
    J S Nguyen-Van-Tam
    Division of Epidemiology and Public Health, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
    Thorax 65:645-51. 2010
    ..The clinical characteristics of UK patients hospitalised with pandemic H1N1 infection and risk factors for severe outcome are described...
  4. ncbi Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    N Engl J Med 351:1296-305. 2004
    ..End-stage renal disease substantially increases the risks of death, cardiovascular disease, and use of specialized health care, but the effects of less severe kidney dysfunction on these outcomes are less well defined...
  5. ncbi Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico
    Rogelio Perez-Padilla
    National Institute of Respiratory Diseases, Mexico City, Mexico
    N Engl J Med 361:680-9. 2009
    ....
  6. ncbi The burden of respiratory syncytial virus infection in young children
    Caroline Breese Hall
    Department of Pediatrics, The University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    N Engl J Med 360:588-98. 2009
    ..The primary role of respiratory syncytial virus (RSV) in causing infant hospitalizations is well recognized, but the total burden of RSV infection among young children remains poorly defined...
  7. ncbi Critically Ill patients with 2009 influenza A(H1N1) in Mexico
    Guillermo Dominguez-Cherit
    Division of Pulmonary and Critical Care Dr Domínguez Cherit, Hospital Epidemiology Department, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    JAMA 302:1880-7. 2009
    ..In March 2009, novel 2009 influenza A(H1N1) was first reported in the southwestern United States and Mexico. The population and health care system in Mexico City experienced the first and greatest early burden of critical illness...
  8. ncbi Prevalence, expenditures, and complications of multiple chronic conditions in the elderly
    Jennifer L Wolff
    Department of Health Policy and Management, The Johns Hopkins University Bloomberg School of Public Health, 624 N Broadway, Room 304, Baltimore, MD 21205, USA
    Arch Intern Med 162:2269-76. 2002
    The prevalence, health care expenditures, and hospitalization experiences are important considerations among elderly populations with multiple chronic conditions.
  9. pmc Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases
    Francesca Dominici
    Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    JAMA 295:1127-34. 2006
    ..5 microm in aerodynamic diameter [PM2.5]) is limited. Results from the new national monitoring network for PM2.5 make possible systematic research on health risks at national and regional scales...
  10. pmc Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
    Munir Pirmohamed
    Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GE
    BMJ 329:15-9. 2004
    ..To ascertain the current burden of adverse drug reactions (ADRs) through a prospective analysis of all admissions to hospital...
  11. ncbi Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003
    Viktor Y Dombrovskiy
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Crit Care Med 35:1244-50. 2007
    To determine recent trends in rates of hospitalization, mortality, and hospital case fatality for severe sepsis in the United States.
  12. ncbi Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina
    Romina Libster
    Fundacion INFANT, Buenos Aires
    N Engl J Med 362:45-55. 2010
    ..While the Northern Hemisphere experiences the effects of the 2009 pandemic influenza A (H1N1) virus, data from the recent influenza season in the Southern Hemisphere can provide important information on the burden of disease in children...
  13. pmc Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study
    W S Lim
    Respiratory Infection Research Group, Respiratory Medicine, Nottingham City Hospital, Nottingham NG5 1PB, UK
    Thorax 58:377-82. 2003
    ..A multicentre study was conducted to derive and validate a practical severity assessment model for stratifying adults hospitalised with CAP into different management groups...
  14. pmc Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005
    Eili Klein
    Resources for the Future, Washington DC, USA
    Emerg Infect Dis 13:1840-6. 2007
    ..However, the recent magnitude and trend of these infections have not been reported. We used national hospitalization and resistance data to estimate the annual number of hospitalizations and deaths associated with S...
  15. pmc The severity of pandemic H1N1 influenza in the United States, from April to July 2009: a Bayesian analysis
    Anne M Presanis
    Medical Research Council Biostatistics Unit, Cambridge, United Kingdom
    PLoS Med 6:e1000207. 2009
    ..We sought to estimate the probabilities that symptomatic infection would lead to hospitalization, ICU admission, and death by combining data from multiple sources.
  16. pmc Global illness and deaths caused by rotavirus disease in children
    Umesh D Parashar
    Viral Gastroenteritis Section, Division of Viral and Ricksettial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop G04, Atlanta, GA 30333, USA
    Emerg Infect Dis 9:565-72. 2003
    ..mild cases requiring home care alone, moderate cases requiring a clinic visit, and severe cases requiring hospitalization) and death rates in countries in different World Bank income groups...
  17. pmc Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis
    Maria D Van Kerkhove
    Global Influenza Programme, World Health Organization
    PLoS Med 8:e1001053. 2011
    ....
  18. ncbi Hospitalization-associated disability: "She was probably able to ambulate, but I'm not sure"
    Kenneth E Covinsky
    Department of Medicine and Division of Geriatrics, University of California, San Francisco, San Francisco, CA 94121, USA
    JAMA 306:1782-93. 2011
    In older patients, acute medical illness that requires hospitalization is a sentinel event that often precipitates disability...
  19. ncbi Population trends in the incidence and outcomes of acute myocardial infarction
    Robert W Yeh
    Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    N Engl J Med 362:2155-65. 2010
    ..Few studies have characterized recent population trends in the incidence and outcomes of myocardial infarction...
  20. ncbi Evidence suggesting that a chronic disease self-management program can improve health status while reducing hospitalization: a randomized trial
    K R Lorig
    Stanford University School of Medicine, California, USA
    Med Care 37:5-14. 1999
    ..It also explored the differential effectiveness of the intervention for subjects with specific diseases and comorbidities...
  21. ncbi Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California
    Janice K Louie
    California Department of Public Health, 850 Marina Bay Pkwy, Richmond, CA 94804, USA
    JAMA 302:1896-902. 2009
    ..Pandemic influenza A(H1N1) emerged rapidly in California in April 2009. Preliminary comparisons with seasonal influenza suggest that pandemic 2009 influenza A(H1N1) disproportionately affects younger ages and causes generally mild disease...
  22. ncbi Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study
    Sonal Singh
    Department of Medicine, The Johns Hopkins University School of Medicine and Public Health, Baltimore, MD 21287, USA
    JAMA Intern Med 173:534-9. 2013
    ....
  23. ncbi The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children
    K M Neuzil
    Department of Medicine, University of Washington School of Medicine, Seattle, USA
    N Engl J Med 342:225-31. 2000
    ..We measured the disease burden of influenza in a large cohort of healthy children in the Tennessee Medicaid program who were younger than 15 years of age...
  24. pmc Risk prediction models for hospital readmission: a systematic review
    Devan Kansagara
    Department of General Internal Medicine, Portland Veterans Affairs Medical Center, Mailcode RD71, 3710 SW US Veterans Hospital Rd, Portland, OR 97239, USA
    JAMA 306:1688-98. 2011
    ..Predicting hospital readmission risk is of great interest to identify which patients would benefit most from care transition interventions, as well as to risk-adjust readmission rates for the purposes of hospital comparison...
  25. pmc Long-term exposure to traffic-related air pollution and the risk of coronary heart disease hospitalization and mortality
    Wen Qi Gan
    School of Environmental Health, University of British Columbia, Vancouver, British Columbia, Canada
    Environ Health Perspect 119:501-7. 2011
    ..Epidemiologic studies have demonstrated that exposure to road traffic is associated with adverse cardiovascular outcomes...
  26. pmc Telemonitoring in patients with heart failure
    Sarwat I Chaudhry
    Section of General Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA
    N Engl J Med 363:2301-9. 2010
    ..Small studies suggest that telemonitoring may improve heart-failure outcomes, but its effect in a large trial has not been established...
  27. ncbi Physical activity and hospitalization for exacerbation of COPD
    Fabio Pitta
    Respiratory Rehabilitation and Respiratory Division, University Hospital Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
    Chest 129:536-44. 2006
    ..6-min walking distance, and arterial blood gas levels in 17 patients (mean age, 69 +/- 9 years [+/- SD]; body mass index, 24 +/- 5 kg/m(2)) at the beginning and end of a hospitalization period for an AE and 1 month after discharge.
  28. pmc Changes in severity of 2009 pandemic A/H1N1 influenza in England: a Bayesian evidence synthesis
    A M Presanis
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge CB2 0SR, UK
    BMJ 343:d5408. 2011
    ....
  29. pmc Fine particulate air pollution and its components in association with cause-specific emergency admissions
    Antonella Zanobetti
    Department of Environmental Health, School of Public Health, Harvard University, Boston, MA, USA
    Environ Health 8:58. 2009
    ..We explored whether the association between cause-specific hospital admissions and PM(2.5) was modified by PM(2.5) chemical composition...
  30. pmc Incidence, seasonality and mortality associated with influenza pneumonia in Thailand: 2005-2008
    James Mark Simmerman
    International Emerging Infections Program, Thailand Ministry of Public Health United States Centers for Disease Control Collaboration, Nonthaburi, Thailand
    PLoS ONE 4:e7776. 2009
    ..Prospective data from multiple years are needed to develop vaccine policy and treatment guidelines, and improve pandemic preparedness...
  31. ncbi Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders
    Hjördis O Atladóttir
    Department of Epidemiology, Institute of Public Health, University of Aarhus, Bartholins Alle 2, Arhus C, Denmark
    J Autism Dev Disord 40:1423-30. 2010
    ..98 (CI: 1.29-7.15) and adjusted hazard ratio = 1.42 (CI: 1.08-1.87), respectively. Our results support prior hypotheses concerning early prenatal viral infection increasing the risk of ASDs...
  32. ncbi Rosuvastatin in older patients with systolic heart failure
    John Kjekshus
    Department of Cardiology, University of Oslo, Rikshospitalet University Hospital, Oslo, Norway
    N Engl J Med 357:2248-61. 2007
    ..Patients with systolic heart failure have generally been excluded from statin trials. Acute coronary events are uncommon in this population, and statins have theoretical risks in these patients...
  33. ncbi Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States
    Alicia M Siston
    Epidemic Intelligence Service, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 303:1517-25. 2010
    Early data on pandemic 2009 influenza A(H1N1) suggest pregnant women are at increased risk of hospitalization and death.
  34. ncbi A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia
    Jari Tiihonen
    Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland
    Am J Psychiatry 168:603-9. 2011
    ..The authors examined the risk of rehospitalization and drug discontinuation in a nationwide cohort of 2,588 consecutive patients hospitalized for the first time with a diagnosis of schizophrenia between 2000 and 2007 in Finland...
  35. pmc Reduction of catastrophic health care expenditures by a community-based health insurance scheme in Gujarat, India: current experiences and challenges
    Michael Kent Ranson
    Health Policy Unit, London School of Hygiene and Tropical Medicine, London, England
    Bull World Health Organ 80:613-21. 2002
    ..Women's Association's Medical Insurance Fund in Gujarat in terms of insurance coverage according to income groups, protection of claimants from costs of hospitalization, time between discharge and reimbursement, and frequency of use.
  36. pmc Food-related illness and death in the United States
    P S Mead
    Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 5:607-25. 1999
    ..Overall, foodborne diseases appear to cause more illnesses but fewer deaths than previously estimated...
  37. ncbi Influenza-associated hospitalizations in the United States
    William W Thompson
    Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 292:1333-40. 2004
    ..Respiratory viral infections are responsible for a large number of hospitalizations in the United States each year...
  38. pmc The population-based burden of influenza-associated hospitalization in rural western Kenya, 2007-2009
    Daniel R Feikin
    Centers for Disease Control and Prevention, PO Box 1578, Kisumu, Kenya
    Bull World Health Organ 90:256-263A. 2012
    To estimate the burden and age-specific rates of influenza-associated hospitalization in rural western Kenya.
  39. pmc Causes of acute hospitalization in adolescence: burden and spectrum of HIV-related morbidity in a country with an early-onset and severe HIV epidemic: a prospective survey
    Rashida A Ferrand
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Med 7:e1000178. 2010
    ..However, the overall impact on adolescent health in settings with high HIV seroprevalence has not previously been investigated...
  40. ncbi Reduction in rotavirus-associated acute gastroenteritis following introduction of rotavirus vaccine into Australia's National Childhood vaccine schedule
    Jim P Buttery
    Department of General Medicine and Murdoch Children s Research Institute, Royal Children s Hospital Melbourne, Parkville, Victoria, Australia Paediatric Infectious Diseases Unit, Monash Children s Hospital, Department of Paediatrics, Monash University, Melbourne, Victoria
    Pediatr Infect Dis J 30:S25-9. 2011
    ..This allowed comparison of both vaccines in similar populations with high infant vaccination coverage...
  41. pmc Influenza vaccine given to pregnant women reduces hospitalization due to influenza in their infants
    Isaac Benowitz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Clin Infect Dis 51:1355-61. 2010
    Infants aged <12 months are at high risk of hospitalization for influenza. Influenza vaccine is recommended for pregnant women and for most children; however, no vaccine is approved for infants aged <6 months...
  42. ncbi Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis
    Carlos G Grijalva
    Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
    Lancet 369:1179-86. 2007
    ..We therefore assessed the effect of the programme on rates of all-cause and pneumococcal pneumonia admissions...
  43. ncbi Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)
    Kirkwood F Adams
    Division of Cardiology, University of North Carolina, Chapel Hill, NC, USA
    Am Heart J 149:209-16. 2005
    ..Heart failure is a leading cause of hospitalization for adults older than 65 years in the United States...
  44. ncbi Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus
    P Michael Ho
    Department of Medicine, Denver Veterans Affairs Medical Center, CO, USA
    Arch Intern Med 166:1836-41. 2006
    ..Medication nonadherence may reduce the effectiveness of therapies. To our knowledge, the association between medication nonadherence and mortality remains unexplored outside the context of clinical trials...
  45. pmc National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998-2008
    Jersey Chen
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    JAMA 306:1669-78. 2011
    It is not known whether recent declines in ischemic heart disease and its risk factors have been accompanied by declines in heart failure (HF) hospitalization and mortality.
  46. ncbi Systematic review of the chronic care model in chronic obstructive pulmonary disease prevention and management
    Sandra G Adams
    Department of Medicine, The University of Texas Health Science Center at San Antonio, USA
    Arch Intern Med 167:551-61. 2007
    ....
  47. pmc The 2006 California heat wave: impacts on hospitalizations and emergency department visits
    Kim Knowlton
    Health and Environment Program, Natural Resources Defense Council, New York, New York 10011 4231, USA
    Environ Health Perspect 117:61-7. 2009
    ..Climate models project that heat waves will increase in frequency and severity. Despite many studies of mortality from heat waves, few studies have examined morbidity...
  48. ncbi Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study
    Alexander T Cohen
    King s College Hospital, London, UK
    Lancet 371:387-94. 2008
    ....
  49. ncbi Effect of dronedarone on cardiovascular events in atrial fibrillation
    Stefan H Hohnloser
    Department of Cardiology, J W Goethe University, Frankfurt, Germany
    N Engl J Med 360:668-78. 2009
    ..Dronedarone is a new antiarrhythmic drug that is being developed for the treatment of patients with atrial fibrillation...
  50. ncbi Synchrony, waves, and spatial hierarchies in the spread of influenza
    Cecile Viboud
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Science 312:447-51. 2006
    ..A simple epidemiological model, based on the gravity formulation, captures the observed increase of influenza spatial synchrony with transmissibility; high transmission allows influenza to spread rapidly beyond local spatial constraints...
  51. ncbi Inhaled corticosteroid use in chronic obstructive pulmonary disease and the risk of hospitalization for pneumonia
    Pierre Ernst
    Pharmacoepidemiology Research Unit, Department of Medicine, McGill University Health Centre, and Division of Clinical Epidemiology, Ross 4 29, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, PQ, Quebec, H3A 1A1 Canada
    Am J Respir Crit Care Med 176:162-6. 2007
    ..Inhaled corticosteroids are commonly prescribed to patients with chronic obstructive pulmonary disease (COPD)...
  52. pmc Incidence and severity of respiratory syncytial virus pneumonia in rural Kenyan children identified through hospital surveillance
    D James Nokes
    Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    Clin Infect Dis 49:1341-9. 2009
    ..Although necessary for developing a rationale for vaccination, the burden of severe respiratory syncytial virus (RSV) disease in children in resource-poor settings remains poorly defined...
  53. pmc COPD exacerbations .1: Epidemiology
    G C Donaldson
    Academic Unit of Respiratory Medicine, University College London, UK
    Thorax 61:164-8. 2006
    ..The importance of distinguishing between recurrent and relapsed exacerbations is discussed...
  54. ncbi Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children
    Ian C Michelow
    Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Pediatrics 113:701-7. 2004
    ..The objective of this study was to determine as precisely as possible the epidemiology and morbidity of community-acquired pneumonia in hospitalized children...
  55. ncbi Mortality after hospitalization for COPD
    Pedro Almagro
    Internal Medicine, Hospital Mutua de Terrassa, University of Barcelona, Barcelona, Spain
    Chest 121:1441-8. 2002
    ..To identify variables associated with mortality in patients admitted to the hospital for acute exacerbation of COPD...
  56. ncbi Temporal association between hospitalization and rate of falls after discharge
    J E Mahoney
    Department of Medicine, University of Wisconsin Medical School, 2870 University Ave, Suite 100, Madison, WI 53705, USA
    Arch Intern Med 160:2788-95. 2000
    Evidence suggests that acute illness and hospitalization may increase the risk for falls.
  57. ncbi Effectiveness of influenza vaccine in the community-dwelling elderly
    Kristin L Nichol
    Medicine Service and Center for Chronic Disease Outcomes Research, Minneapolis Veterans Affairs Medical Center and University of Minnesota, Minneapolis 55417, USA
    N Engl J Med 357:1373-81. 2007
    ..This study examined the effectiveness of influenza vaccine in seniors over the long term while addressing potential bias and residual confounding in the results...
  58. ncbi Estimating the burden of 2009 pandemic influenza A (H1N1) in the United States (April 2009-April 2010)
    Sundar S Shrestha
    Division of Diabetes Translation, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Infect Dis 52:S75-82. 2011
    ..percent of deaths occurred in those under 65 years of age with children and working adults having risks of hospitalization and death 4 to 7 times and 8 to 12 times greater, respectively, than estimates of impact due to seasonal ..
  59. ncbi A novel risk factor for a novel virus: obesity and 2009 pandemic influenza A (H1N1)
    Janice K Louie
    Division of Communicable Disease Control, California Department of Public Health, Richmond, California94804, USA
    Clin Infect Dis 52:301-12. 2011
    ..many critically ill patients with 2009 pandemic influenza A (H1N1) (2009 H1N1) infection were noted to be obese, but whether obesity, rather than its associated co-morbidities, is an independent risk factor for severe infection is unknown...
  60. ncbi Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children
    Marika K Iwane
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Pediatrics 113:1758-64. 2004
    ..We established a prospective, active population-based surveillance network to provide precise estimates of hospitalization rates for viral acute respiratory illness (ARI) in young children and to measure the potential impact of ..
  61. pmc Clinical epidemiology of heart failure
    Arend Mosterd
    Department of Cardiology, Meander Medical Centre, Amersfoort, The Netherlands
    Heart 93:1137-46. 2007
    ..Despite an increase in manuscripts describing epidemiological aspects of heart failure since the 1990s, additional information is still needed, as indicated by various editorials...
  62. pmc Emergency admissions for cardiovascular and respiratory diseases and the chemical composition of fine particle air pollution
    Roger D Peng
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Environ Health Perspect 117:957-63. 2009
    ..5) (particulate matter <or= 2.5 microm in aerodynamic diameter) as the indicator. Evidence regarding the toxicity of the chemical components of the PM(2.5) mixture is limited...
  63. ncbi Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: increased vulnerability with age
    Kenneth E Covinsky
    Division of Geriatrics, University of California at San Francisco, San Francisco, California, USA
    J Am Geriatr Soc 51:451-8. 2003
    ..To describe the changes in activities of daily living (ADL) function occurring before and after hospital admission in older people hospitalized with medical illness and to assess the effect of age on loss of ADL function...
  64. ncbi Risk factors for hospitalization and severe outcomes of 2009 pandemic H1N1 influenza in Quebec, Canada
    Rodica Gilca
    Quebec National Institute of Public Health, Quebec City, QC, Canada
    Influenza Other Respir Viruses 5:247-55. 2011
    ....
  65. ncbi Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway St, 3rd Floor, Oakland, California 94612 2304, USA
    Circulation 113:2713-23. 2006
    ..It is unclear, however, whether this relation is explained by underlying kidney disease, treatment differences, or associated comorbidity...
  66. ncbi Severity of 2009 pandemic influenza A (H1N1) virus infection in pregnant women
    Andreea A Creanga
    Epidemic Intelligence Service Program, Office of Workforce and Career Development, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA 30341 3717, USA
    Obstet Gynecol 115:717-26. 2010
    ..To examine 2009 H1N1 influenza illness severity and the effect of antiviral treatment on the severity of illness among pregnant women...
  67. ncbi Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study
    David N Juurlink
    Department of Medicine University of Toronto, Toronto
    N Engl J Med 351:543-51. 2004
    ..Use of angiotensin-converting-enzyme (ACE) inhibitors is also indicated in these patients. However, life-threatening hyperkalemia can occur when these drugs are used together...
  68. pmc Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1) disease
    Oliver W Morgan
    Division of Emerging Infections and Surveillance Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 5:e9694. 2010
    ..We assessed whether obesity is a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1), independent of chronic medical conditions considered by the ..
  69. ncbi Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009
    Seema Jain
    Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 361:1935-44. 2009
    ..We describe the clinical characteristics of patients who were hospitalized with 2009 H1N1 influenza in the United States from April 2009 to mid-June 2009...
  70. pmc Risk factors of readmission to hospital for a COPD exacerbation: a prospective study
    J Garcia-Aymerich
    Respiratory and Environmental Health Research Unit, IMIM, Barcelona, Spain
    Thorax 58:100-5. 2003
    ..The association between readmission for a COPD exacerbation and a wide range of modifiable potential risk factors, after adjusting for sociodemographic and clinical factors, has been assessed...
  71. pmc Risk of severe outcomes among patients admitted to hospital with pandemic (H1N1) influenza
    Alexia Campbell
    Centre for Immunization and Respiratory Infectious Diseases, Infectious Disease and Emergency Preparedness Branch, Public Health Agency of Canada, Ottawa, Ontario
    CMAJ 182:349-55. 2010
    ....
  72. pmc Malaria paediatric hospitalization between 1999 and 2008 across Kenya
    Emelda A Okiro
    Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, P O Box 43640, 00100 GPO, Nairobi, Kenya
    BMC Med 7:75. 2009
    ..Here we present a nationwide assessment of changes over 10 years in paediatric malaria hospitalization across Kenya.
  73. ncbi Smoke-free legislation and hospitalizations for acute coronary syndrome
    Jill P Pell
    University of Glasgow, United Kingdom
    N Engl J Med 359:482-91. 2008
    ..However, it is unknown whether the reduction in admissions involved nonsmokers, smokers, or both...
  74. ncbi Viral loads and duration of viral shedding in adult patients hospitalized with influenza
    Nelson Lee
    Department of Medicine and Therapeutics, Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    J Infect Dis 200:492-500. 2009
    ..The goal of this study was to characterize viral loads and factors affecting viral clearance in persons with severe influenza...
  75. ncbi Heart failure-related hospitalization in the U.S., 1979 to 2004
    Jing Fang
    Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3714, USA
    J Am Coll Cardiol 52:428-34. 2008
    ..The purpose of this study was to determine hospitalizations for heart failure in the U.S. during the past 26 years...
  76. pmc A comparison of SF-36 and SF-12 composite scores and subsequent hospitalization and mortality risks in long-term dialysis patients
    Eduardo Lacson
    Clinical Sciences, Epidemiology, and Research, Fresenius Medical Care, North America, Waltham, Massachusetts 02451 1457, USA
    Clin J Am Soc Nephrol 5:252-60. 2010
    ..The study compared physical and mental component summary (PCS/MCS) scores from the SF-36 with those from the embedded SF-12 in a national cohort of dialysis patients...
  77. ncbi Down syndrome and hospitalizations due to respiratory syncytial virus: a population-based study
    Philip Zachariah
    Department of Pediatrics, University of Colorado, Denver, CO, USA
    J Pediatr 160:827-31.e1. 2012
    To assess the risk estimates for respiratory syncytial virus (RSV) hospitalization in children with Down syndrome (DS) and the clinical features and severity of RSV lower respiratory tract infection (LRTI) in hospitalized children.
  78. ncbi Predicting outcomes following hospitalization for acute exacerbations of COPD
    J Steer
    North Tyneside General Hospital, Northumbria Health NHS Foundation Trust, Rake Lane, North Shields, Tyne and Wear, NE29 8NH, UK
    QJM 103:817-29. 2010
    ....
  79. ncbi Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization
    Michael I Polkey
    NIHR Respiratory Biomedical Research Unit at the Royal Brompton Hospital and Imperial College London, London, United Kingdom
    Am J Respir Crit Care Med 187:382-6. 2013
    ..Estimates of the minimal clinically important difference for the 6-minute-walk distance (6MWD) have been derived from narrow cohorts using nonblinded intervention...
  80. ncbi Cardiac-resynchronization therapy for mild-to-moderate heart failure
    Anthony S L Tang
    Island Medical Program, University of British Columbia, Vancouver, Canada
    N Engl J Med 363:2385-95. 2010
    ..Most of these patients are candidates for an implantable cardioverter-defibrillator (ICD). We evaluated whether adding CRT to an ICD and optimal medical therapy might reduce mortality and morbidity among such patients...
  81. pmc Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United States
    Lone Simonsen
    Sage Analytica, Bethesda, Maryland, USA
    MBio 2:e00309-10. 2011
    ..State Inpatient Databases (SID) for 1996 to 2006 from 10 states; SID contain 100% samples of ICD9-coded hospitalization data for the selected states...
  82. ncbi Increased risk of hospitalization for acute lower respiratory tract infection among Australian indigenous infants 5-23 months of age following pneumococcal vaccination: a cohort study
    Kerry Ann F O'Grady
    Child Health Division, Menzies School of Health Research, Charles Darwin University, Tiwi, London, England
    Clin Infect Dis 50:970-8. 2010
    ..We evaluated this program's effectiveness in reducing the risk of hospitalization for acute lower respiratory tract infection (ALRI) in Northern Territory (NT) Indigenous children aged 5-23 ..
  83. pmc Muscle force during an acute exacerbation in hospitalised patients with COPD and its relationship with CXCL8 and IGF-I
    M A Spruit
    Respiratory Rehabilitation and Respiratory Division, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Thorax 58:752-6. 2003
    ..The effect of an acute exacerbation on quadriceps peak torque (QPT) was therefore studied in hospitalised patients, and the aforementioned correlations were examined in hospitalised and in stable patients...
  84. ncbi Long-term clinical course of patients after termination of ventricular tachyarrhythmia by an implanted defibrillator
    Arthur J Moss
    Cardiology Unit of the Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Circulation 110:3760-5. 2004
    ..This analysis from the MADIT-II trial database examines the long-term clinical course and subsequent mortality risk of patients after termination of life-threatening ventricular tachyarrhythmias by an ICD...
  85. ncbi Home telehealth for chronic obstructive pulmonary disease: a systematic review and meta-analysis
    Julie Polisena
    Canadian Agency for Drugs and Technologies in Health CADTH, Ottawa, Ontario, Canada
    J Telemed Telecare 16:120-7. 2010
    ..Home telehealth (home telemonitoring and telephone support) was found to reduce rates of hospitalization and emergency department visits, while findings for hospital bed days of care varied between studies...
  86. ncbi IScore: a risk score to predict death early after hospitalization for an acute ischemic stroke
    Gustavo Saposnik
    Stroke Outcomes Research Centre, Stroke Outcome Research Canada Working Group, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Toronto, Ontario, Canada
    Circulation 123:739-49. 2011
    ..Our aim was to identify predictors of mortality and to develop and validate a risk score model using information available at hospital presentation...
  87. pmc Diabetes, glycemic control, and risk of hospitalization with pneumonia: a population-based case-control study
    Jette B Kornum
    Department of Clinical Epidemiology, Aarhus University Hospital, Aalborg, Denmark
    Diabetes Care 31:1541-5. 2008
    To examine whether diabetes is a risk factor for hospitalization with pneumonia and to assess the impact of A1C level on such risk.
  88. ncbi Transitional care of older adults hospitalized with heart failure: a randomized, controlled trial
    Mary D Naylor
    Gerontological Nursing Science Center, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Geriatr Soc 52:675-84. 2004
    ..To examine the effectiveness of a transitional care intervention delivered by advanced practice nurses (APNs) to elders hospitalized with heart failure...
  89. pmc Contrasting patterns of mortality and hospital admissions during hot weather and heat waves in Greater London, UK
    R S Kovats
    Public and Environmental Health Research Unit, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Occup Environ Med 61:893-8. 2004
    ..Epidemiological research has shown that mortality increases during hot weather and heat waves, but little is known about the effect on non-fatal outcomes in the UK...
  90. ncbi Pandemic influenza in Canadian children: a summary of hospitalized pediatric cases
    Julie A Bettinger
    Vaccine Evaluation Center, BC Children s Hospital and the University of British Columbia, Vancouver, BC, Canada
    Vaccine 28:3180-4. 2010
    ..Close to 50% of children received antiviral medication. Two children died from the infection. The pediatric risk groups affected and course of disease caused by pandemic H1N1 appear similar to seasonal influenza...
  91. pmc Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population
    Shevin T Jacob
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA
    PLoS ONE 4:e7782. 2009
    ..We conducted a prospective observational study reporting the management and outcomes of severely septic patients in two Ugandan hospitals. We describe their epidemiology, management, and clinical correlates for mortality...
  92. ncbi Home telemonitoring for congestive heart failure: a systematic review and meta-analysis
    Julie Polisena
    Canadian Agency for Drugs and Technologies in Health, Ottawa, Ontario, Canada
    J Telemed Telecare 16:68-76. 2010
    ..More studies of higher methodological quality are required to give more precise information about the potential clinical effectiveness of home telehealth interventions...
  93. ncbi Infant rotavirus vaccination may provide indirect protection to older children and adults in the United States
    Ben A Lopman
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 204:980-6. 2011
    ..This study demonstrates a previously unrecognized burden of severe rotavirus in the population >5 years and the primacy of very young children in the transmission of rotavirus...
  94. ncbi Hospitalized patients with 2009 pandemic influenza A (H1N1) virus infection in the United States--September-October 2009
    Jacek Skarbinski
    Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Clin Infect Dis 52:S50-9. 2011
    ....
  95. pmc Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children
    C S Murray
    Academic Division of Medicine and Surgery South, The University of Manchester, North West Lung Centre, South Manchester University Hospitals NHS Trust, Manchester M23 9LT, UK
    Thorax 61:376-82. 2006
    ..A study was undertaken to investigate the importance of allergen exposure in sensitised individuals in combination with viral infections and other potentially modifiable risk factors precipitating asthma hospital admission in children...
  96. pmc Reducing occurrence and severity of pneumonia due to pandemic H1N1 2009 by early oseltamivir administration: a retrospective study in Mexico
    Anjarath Lorena Higuera Iglesias
    National Institute for Respiratory Disease, Mexico City, Mexico
    PLoS ONE 6:e21838. 2011
    ..Therefore, we aimed to determine how time from symptom onset to antiviral administration affected the effectiveness of antiviral treatment against pneumonia due to pandemic (H1N1) 2009...
  97. ncbi Description of antiviral treatment among adults hospitalized with influenza before and during the 2009 pandemic: United States, 2005-2009
    Saumil Doshi
    Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Infect Dis 204:1848-56. 2011
    ..We compared antiviral use among adults hospitalized with influenza before and during the pandemic...
  98. ncbi Dementia in the acute hospital: prospective cohort study of prevalence and mortality
    Elizabeth L Sampson
    Marie Curie Palliative Care Research Unit, Department of Mental Health Sciences, University College Medical School, Hampstead Campus, Rowland Hill Street, London NW3 2PF, UK
    Br J Psychiatry 195:61-6. 2009
    ..Increasing numbers of people will die with dementia, many in the acute hospital. It is often not perceived to be a life-limiting illness...
  99. pmc Risk of cancer following hospitalization for type 2 diabetes
    Kari Hemminki
    Division of Molecular Genetic Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Oncologist 15:548-55. 2010
    ..Cancer and type 2 diabetes (T2D) are two common diseases that may share risk factors. We aimed at determining subsequent cancer risks in patients hospitalized for T2D in Sweden...
  100. pmc A cross-sectional study of the microeconomic impact of cardiovascular disease hospitalization in four low- and middle-income countries
    Mark D Huffman
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
    PLoS ONE 6:e20821. 2011
    ..To estimate individual and household economic impact of cardiovascular disease (CVD) in selected low- and middle-income countries (LMIC)...
  101. ncbi Fatalities associated with the 2009 H1N1 influenza A virus in New York city
    Ellen H Lee
    Bureau of Communicable Disease, Division of Disease Control, New York City Department of Health and Mental Hygiene, New York, USA
    Clin Infect Dis 50:1498-504. 2010
    ..Among all hospitalized patients, decedents had presented for hospitalization later (median, 3 vs 2 days after illness onset; P < .05) and received oseltamivir later (median, 6...

Research Grants85

  1. Myocardial Salvage With a Novel Reperfusion Therapy
    CONSTANCE WILSON; Fiscal Year: 2005
    ..the heart following angioplasty procedures and coronary artery bypass graft surgery can affect the length of hospitalization, cost of hospitalization, functional capacity of the patient at discharge, and may ultimately contribute to ..
  2. ASTHMA AND ALLERGIC DISEASE CENTER
    Thomas A Platts Mills; Fiscal Year: 2010
    ..In particular asthma has become an important cause of school absenteeism, hospitalization and mortality among populations living in poverty in the cities of the United States...
  3. A Hybrid PARP Inhibitor and Redox Catalyst for Lung Transplantation
    GARRY JOHN SOUTHAN; Fiscal Year: 2012
    ..endpoints in LIRI of decreased: 1) pulmonary shunt, 2) duration of mechanical ventilation, 3) length of hospitalization, and 4) all-cause 30 and 365 day mortality...
  4. N-methanocarbathymidine (N-MCT) for the Treatment of Herpes and Pox Virus Infecti
    Aquilur Rahman; Fiscal Year: 2010
    ..N- MCT has no apparent cytotoxicity in uninfected tissues, in contrast to cidofovir, which requires hospitalization to treat its associated renal toxicity...
  5. Mitochondrial dysfunction, oxidative stress, and surgical acute kidney injury
    FREDERIC TREMAINE BILLINGS; Fiscal Year: 2013
    ..cardiac surgery to placebo, 1200 mg, or 2400 mg of ubiquinone-10 five days prior to surgery and daily during hospitalization and test the effect of ubiquinone-10 dose on mitochondrial function and oxidative stress...
  6. Combination drug treatment to inhibit multiple cell death pathways after TBI
    ALAN IRA FADEN; Fiscal Year: 2010
    ..A disability prevalence of 37% has been reported for TBI patients followed more than one year after hospitalization;based on this figure, the CDC has estimated that nearly 2% of the entire US population has TBI-related ..
  7. Lactoferrin Enhances Growth and Reduces Nosocomial Infection in Preterm Infants
    Karel Petrak; Fiscal Year: 2009
    ..and 46% of infants born at less than 25 weeks'gestation experience a serious NIs during hospitalization in the NICU. The most common NI sites were sepsis and NEC...
  8. Development of Vaccines against Clostridium difficile Infection
    SAUL R TZIPORI; Fiscal Year: 2013
    ..difficile infection (CDI) has increased significantly in both North America and Europe, causing lengthy hospitalization, substantial morbidity and mortality...
  9. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert J Thomas; Fiscal Year: 2010
    ..We will in parallel track the progress of heart failure patients from a hospitalization episode for 6 months, attempting to show that reductions of HFC and emergence or increases in narrow band e-..
  10. Chronic Electrical Stimulation to Reduce Bladder Hyperreflexia after SCI
    Kenneth J Gustafson; Fiscal Year: 2012
    ..renal damage and consequent renal dialysis or transplantation which can lead to recurrent and costly hospitalization. This project directly addresses the problem of neurogenic bladder by providing a means to reduce bladder ..
  11. Effect of Lactobacillus GG on gut permeability and microbiome in VLBW neonates
    ROSE MARIE VISCARDI; Fiscal Year: 2013
    ..experience significant morbidity including post-surgical short bowel syndrome, poor growth, prolonged hospitalization, and long-term neurodevelopmental impairments...
  12. C. Difficile Outcomes and Effectiveness of Treatment Strategies in SCI
    Charlesnika T Evans; Fiscal Year: 2013
    ..is whether SCI/D veterans will be included more than once in the analyses or just once each year, or for each hospitalization. If all hospitalizations are used, how will this be adjusted for in the analyses? If a patient is only used ..
  13. Transforming PCI Informed Consent into an Evidence-based Decision-making Tool
    John A Spertus; Fiscal Year: 2010
    ..Major bleeding events also result in a 3-4 day increase in length of stay,11 in turn increasing hospitalization costs by $6,000-8,000...
  14. Mechanisms of innate immune response modulation by mechanical ventilation
    William A Altemeier; Fiscal Year: 2012
    ..Additionally, the economic impact of ALI is high secondary to prolonged ICU care and overall length of hospitalization and to chronic post-hospitalization disability...
  15. Severe H1N1 Influenza Infection During Pregnancy: Pathophysiologic Mechanisms
    Mark Phillippe; Fiscal Year: 2010
    ..S. Among these 34 pregnant women, 11 (32%) required hospitalization, three were admitted to intensive care and one died. This CDC report also noted that among 45 deaths in the U...
  16. B Cell Development in Aging
    John C Cambier; Fiscal Year: 2010
    ..Such people require increased medical care and hospitalization, impacting public health primarily in economic terms...
  17. Pain and Hypoxia in Premature Neonates
    DANILYN MAG AKAT ANGELES; Fiscal Year: 2012
    ..admitted to the neonatal intensive care unit (NICU) require up to several hundred procedures during their hospitalization. Many of these are tissue damaging procedures (TDPs) that cause pain...
  18. Optimizing Chronic Disease Prevention and Management in Advanced Dementia
    Jennifer Tjia; Fiscal Year: 2010
    ..Data sources for these populations include: drug claims for all dispensed medications;resident demographics;hospitalization claims;NH facility characteristics and mortality...
  19. Effect of Ultrafiltration on Clinical Outcomes and Health-related Quality of Life
    KELLY VICTORIA LIANG; Fiscal Year: 2013
    ..Specific Aim 2. To assess short-term and long-term clinical endpoints, including length of hospitalization and number of rehospitalizations, after early initiation of UF compared to usual care. Specific Aim 3...
  20. Prevalence and Impact of Frailty among Dialysis Patients
    Kirsten L Johansen; Fiscal Year: 2013
    ..and functioning, initially observed in the elderly, that ultimately results in increased risk of disability, hospitalization, institutionalization, and death...
  21. A novel role for endogenous fructose in ischemic acute kidney injury
    MIGUEL ANGEL LANASPA GARCIA; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Acute kidney injury is a common cause of hospitalization with high mortality affecting 30% of patients admitted to the intensive care unit...
  22. Combination Clostridium Difficile Toxin and Adhesin Vaccine
    Ciaran P Kelly; Fiscal Year: 2013
    ..Broad spectrum antibiotic usage, hospitalization, advanced age and comorbidities increase the risk for acquiring CDAD...
  23. Tick-Mammal Interface of Human Granulocytic Anaplasmosis
    ULRIKE GERTRUD MUNDERLOH; Fiscal Year: 2013
    ..The agent, Anaplasma phagocytophilum, causes sudden onset of high fever during the summer months requiring hospitalization for 40% of patients and has a fatal outcome in ~5% of clinical cases...
  24. Pathogenesis of cognitive/neurologic deficits in central nervous system malaria
    Chandy C John; Fiscal Year: 2012
    ..6% of children >5 years of age who survive CM have cognitive deficits 6 months after hospitalization. However, the effects of CM on cognition in younger children have not been prospectively characterized, and ..
  25. Evaluation of a new class of antimicrobial agents against Clostridium difficile
    SAUL R contact TZIPORI; Fiscal Year: 2011
    ..inflammatory disease, has increased significantly in both North America and Europe, causing lengthy hospitalization and substantial morbidity and mortality...
  26. Muscle Wasting in Uremia
    Ralph Rabkin; Fiscal Year: 2012
    ..on the impact of disuse on the muscle wasting in the patient with advanced kidney failure, even though hospitalization is frequent...
  27. Mechanisms of Pleural Fibrosis in Empyema
    Kamal A Mohammed; Fiscal Year: 2013
    ..The clinical management of empyema is associated with prolonged hospitalization, and instrumentation of the pleural space with significant patient discomfort...
  28. Combination Clostridium Difficile Toxin and Adhesin Vaccine
    Ciaran P Kelly; Fiscal Year: 2011
    ..Broad spectrum antibiotic usage, hospitalization, advanced age and comorbidities increase the risk for acquiring CDAD...
  29. Community Ambulation Following Hip Fracture
    Jay Magaziner; Fiscal Year: 2013
    ..Health Center) will recruit a total of 300 community dwelling hip fracture patients (aged 65+) following hospitalization, and randomly assign them to a 16-week high intensity, supervised, home delivered multi-component exercise ..
  30. Conservative Versus Dialytic Management in Stage V Chronic Kidney Disease
    GLENN MATTHEW CHERTOW; Fiscal Year: 2010
    ..experience unacceptably high mortality rates (in excess of 20% per year), exceptionally high rates of hospitalization (more than two hospitalizations per patient per year, spending on average a fortnight per year in hospital), ..
  31. Coping Skills Training in Heart Failure: Outcomes and Mechanisms
    Andrew Sherwood; Fiscal Year: 2013
    ..therapy, symptom instability and clinical deterioration are common and lead to frequent physician visits, hospitalization, and ultimately death...
  32. Biomarkers of Sudden Death and Progressive Heart Failure
    GORDON FRANK TOMASELLI; Fiscal Year: 2010
    ..case management programs have demonstrated positive effects on mortality, quality of life, and length of hospitalization in these patients...
  33. Gq-coupled Receptors Inhibit PI 3-kinase/Akt Signaling Pathway
    Richard Z Lin; Fiscal Year: 2012
    ..This animal model mimics the process of muscle unloading and reloading that can occur during hospitalization. The degree of muscle atrophy and subsequent regrowth is monitored by microCT scans of muscle mass in the ..
  34. Routine Aspiration of Residual Gastric Contents in Very Low Birth Weight Infants
    Leslie A Parker; Fiscal Year: 2013
    ..more hours requiring a central venous line (CVL), increased risk of late onset sepsis (LOS), prolonged hospitalization, as well as disturbances in gastrointestinal (GI) integrity and function...
  35. Development of Inhaled Vancomycin for Treatment of MRSA Infections in CF
    Taneli Jouhikainen; Fiscal Year: 2012
    ..It is envisioned to improve lung function, as well as, to decrease hospitalization rates and use of intravenous (IV) antibiotics...
  36. Causes of rotavirus vaccine failure in Zambian children
    Roma Chilengi; Fiscal Year: 2013
    ..In Zambia, it is responsible for a third of all diarrhea-associated hospitalization and death in children under 5 years...
  37. Vascular Structure and Function in Arteriovenous Fistula Maturation
    Jonathan Himmelfarb; Fiscal Year: 2012
    ..Vascular access dysfunction is associated with patient morbidity and mortality, is a leading reason for hospitalization among dialysis patients, and is estimated to have annual associated costs in the United States that exceed 1 ..
  38. Transfusion Trigger Trial in Coronary Artery Disease: A Pilot Study
    JEFFREY LEE CARSON; Fiscal Year: 2010
    ..angina, or 4) stable coronary artery disease patient who undergoing cardiac catherization during the index hospitalization with at least 70% obstruction by visual inspection...
  39. Trial of Late SURFactant (TOLSURF) to Prevent BPD - Clinical Coord Ctr
    ROBERTA ANDERSON BALLARD; Fiscal Year: 2013
    ..Secondary outcomes include discharge off respiratory support at 40 wk (term), duration of ventilation and hospitalization, and pulmonary morbidity and neurodevelopmental outcome at 1 and 2 years of age...
  40. Trial Of Late SURFactant (TOLSURF) to Prevent BPD-Data Coordinating Center
    Dennis M Black; Fiscal Year: 2013
    ..Secondary outcomes include discharge off respiratory support at 40 wk (term), duration of ventilation and hospitalization, and pulmonary morbidity and neurodevelopmental outcome at 1 and 2 years of age...
  41. Mechanisms of Renoprotection by Soluble Epoxide Hydrolase Inhibition
    Deanna L Kroetz; Fiscal Year: 2013
    ..syndrome occurring in 20% to 30% of critically ill patients, and is associated with increased mortality, hospitalization, use of healthcare resources, and costs...
  42. Epithelium, dendritic cells, and Clostridium difficile associated colitis
    Hanping Feng; Fiscal Year: 2013
    ..difficile infection (CDI) has increased significantly in both North America and Europe, causing lengthy hospitalization, substantial morbidity and mortality...
  43. Enhancement of Dendritic Cells After Burn Injury
    Tracy Toliver Kinsky; Fiscal Year: 2009
    ..Patients with severe bums are at risk for the development of nosocomial infections that can prolong hospitalization and increase morbidity and mortality...
  44. Fatty Acids and Heart Failure in the Physicians'Health Study
    Luc Djousse; Fiscal Year: 2013
    Heart failure (HF) is the leading cause of hospitalization among elderly people in the US with an annual incidence rate of 550,000 cases. Despite advances in medical and surgical treatment, mortality after the onset of HF remains high...
  45. Nutrition Intervention to Reduce Symptoms in Patients with Advanced Heart Failure
    Terry A Lennie; Fiscal Year: 2013
    ..Patients will be followed for an additional 6 months by telephone to collect longer term data on symptom burden and quality of life as well as heart failure hospitalization and all-cause mortality at 9 and 12 months.
  46. MURINE TYPHUS: VECTOR BIOLOGY AND TRANSMISSION
    Abdu F Azad; Fiscal Year: 2013
    ..Murine typhus is a debilitating disease with over 70% of patients requiring hospitalization. Since the disease does not effectively respond to broad-spectrum antibiotics misdiagnosis and treatment ..
  47. Pharmacogenetics of ACE inhibitor-associated angioedema
    NANCY JOAN BROWN; Fiscal Year: 2013
    ..Although generally safe, ACE inhibitors rarely cause angioedema, which can result in hospitalization, intubation or tracheotomy, and even death...
  48. 1st Tier Drugs+Theophylline in Pediatric Severe Asthma
    JERRY JOHN ZIMMERMAN; Fiscal Year: 2010
    ..childhood chronic disease affecting nearly 15 million children, and represents the most common cause of hospitalization among children in the United States, nearly 500,000 annually...
  49. Prognosis and Effectiveness of Advanced Lung Cancer Treatment in the Elderly
    Juan P Wisnivesky; Fiscal Year: 2010
    ..for combined chemoradiation;and 5) assess the prevalence and identify predictors of severe toxicity requiring hospitalization due to chemotherapy and RT in older patients with advanced stage NSCLC treated in the community...
  50. Development of Extracellular Heat Shock Protein-90 as a Novel Topical Wound Heali
    Wei Li; Fiscal Year: 2013
    ..is approaching 100,000 in the US due to non-healing diabetic ulcers, in which a single surgical procedure and hospitalization alone can cost $65,000...
  51. Membrane-associated PDE3-binding proteins in human myocardium
    Matthew A Movsesian; Fiscal Year: 2013
    ..Its annual mortality among veterans is now 12.6%, and morality and hospitalization rates are rising...
  52. Diagnosis of sub-clinical cryptic group A streptococcal myonecrosis
    Amy Evelyn Bryant; Fiscal Year: 2013
    ..Survivors undergo extensive surgical debridement including amputations and prolonged hospitalization. The single most important factor contributing to the exceedingly high morbidity and mortality in these ..
  53. Viral Gene Expression to Therapeutic Levels in Models of Heart Failure
    Joseph E Rabinowitz; Fiscal Year: 2012
    ..NARRATIVE In the United States heart failure is a major cause of mortality. In addition, the cost of hospitalization and missed work is a drain on our economy...
  54. PITCH HF (CCC) Lead Application
    Marc J Semigran; Fiscal Year: 2013
    ..Three Aims address: (1) Time to the primary endpoint (cardiovascular (CV) mortality or HF hospitalization) and secondary endpoints (time to CV mortality, HF hospitalization, all-cause mortality;and frequency of CV/..
  55. Epidemiologic Study of Sick Sinus Syndrome
    Alvaro Alonso; Fiscal Year: 2012
    ..SSS incident events will be identified from hospitalization discharge codes and Medicare (from the Center for Medicare and Medicaid Services (CMS)) data...
  56. Linkage of Lung Inflammation to 8-oxoguanine and OGG1
    ISTVAN STEVEN BOLDOGH; Fiscal Year: 2013
    ..there are approximately twenty million outpatient visits, two million emergency room visits, and half million hospitalization per year related to these diseases...
  57. Maternal Stress, Obesity, and Influenza Virus Vaccine Immunogenicity in Pregnancy
    LISA MICHELLE CHRISTIAN; Fiscal Year: 2013
    ..TIV) is recommended for all pregnant women because they are considered at high risk for complications, hospitalization, and death from influenza...
  58. Analysis of associations between anemia correction in CKD and mortality: CHOIR
    LYNDA ANNE MARIE SZCZECH; Fiscal Year: 2010
    ..disease (CKD) and is associated with increased mortality, increased rates of cardiovascular disease and hospitalization, and decreased quality of life...
  59. South Carolina Study for Adolescents and Young Adults with Rare Conditions
    SUZANNE W MCDERMOTT; Fiscal Year: 2013
    ..We will also describe the frequency and type of health care received by each group, including rates of hospitalization, emergency department visits, and outpatient services, and the cost-effectiveness of different approaches to ..
  60. Augmentation of Innate Anti-Microbial Immunity by TLR4 Agonists
    Edward R Sherwood; Fiscal Year: 2013
    ..Although topical and systemic antibiotics are routinely used, sepsis is the most common cause of prolonged hospitalization and death in burn patients that survive the initial insult...
  61. Anorexia Nervosa: Regional Brain Abnormalites and Relationship to Outcome
    LAURIE MAY MCCORMICK; Fiscal Year: 2013
    ..Treatment of this illness is often prolonged and complicated by high relapse rates after hospitalization, emphasizing the need to identify features that predict treatment response...
  62. Reduced contractile reserve: a therapeutic target in heart failure with normal EF
    Nancy K Sweitzer; Fiscal Year: 2012
    ..No treatment has been shown to affect mortality in HFpEF, which is more than 50% at five years a hospitalization. This project explores the underlying cardiovascular physiology of patients with HFpEF with the goal of ..
  63. Innate immune suppression following experimental injury
    KRISTIN C GREATHOUSE; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Nosocomial infections (NI) during hospitalization in the intensive care unit (ICU) are a significant proportion of health-related cost, morbidity, and mortality in critically injured adults and ..
  64. Access to Care of Medicare and Medicaid Enrollees
    Marlene Niefeld; Fiscal Year: 2003
    ..The results of these problems are increased rates of emergency department use, hospitalization, and mortality...
  65. Shared Decision-Making in End-Stage Heart & Lung Disease
    Mark Sullivan; Fiscal Year: 2005
    ..utilize a qualitative design, separately interviewing patients and spouses and clinicians after a CHF or COPD hospitalization. In our revised proposal, we have omitted our follow-up interviews in order to expand our sample size and ..
  66. Multiple Chronic Conditions in VLBW Infants: Epidemiology, NICU Care, and Outcome
    William Gardner; Fiscal Year: 2010
    ..include death during the NICU stay, cumulative burden of therapies received during the NICU stay, and re- hospitalization within 30 days following discharge from the NICU...
  67. Defining Interoperability Standards for PRO Assessments
    DERSHUNG YANG; Fiscal Year: 2010
    ..assessments in clinical practice, reporting improved physical, functional and emotional well-being, reduced hospitalization, better detections of less observable and subjective PRO concerns, and better patient-provider communication...
  68. BACK PAIN OUTCOME ASSESSMENT TEAM
    Richard Deyo; Fiscal Year: 1991
    ..Back problems result in frequent hospitalization, surgery, and use of expensive diagnostic tests, and wide geographic variations in the use of these services ..
  69. EXERCISE--NURSING INTERVENTION FOR FUNCTIONAL RECOVERY
    Beverly Roberts; Fiscal Year: 2000
    DESCRIPTION (Adapted from the Investigator's Abstract): During hospitalization, many elders experience functional decline characterized by increasing dependence in activities of daily living (ADL) and abnormalities in gait...
  70. Wireless Multichannel Electrocorticogram Recording for Epilepsy Monitoring
    Stuart Cogan; Fiscal Year: 2009
    ..pulled and the grids move;and 6) ten to twenty percent of patients have too few seizures during the hospitalization to identify the epileptic zone with certainty...
  71. NC/OFQ analogs as ORL1 agonists to promote gut motility
    MARK FINDEIS; Fiscal Year: 2005
    ..Clinically, POI has serious impact on patient morbidity, causing patient discomfort and prolongation of hospitalization by 3 to 10 days...
  72. TRAJECTORY OF RECOVERY OF LIFE-SPACE MOBILITY AFTER HOSPITALIZATION
    Cynthia Brown; Fiscal Year: 2009
    ..Methods: Using a prospective cohort study design, participants will be recruited during hospitalization and followed for 6-months after discharge...
  73. INCIDENCE AND OUTCOMES OF VENOUS THROMBOEMBOLISM
    MARC SILVERSTEIN; Fiscal Year: 1993
    Deep vein thrombosis (DVT) and pulmonary embolism (PE) most often occur during hospitalization for surgery or chronic medical conditions...
  74. Alcohol Screening Scores and Medical Outcomes: Age and Gender Influences
    ALEX SOX HARRIS; Fiscal Year: 2009
    ..Therefore, the aims of this R03 study are to determine the sex and age-specific risks of onset and hospitalization for gastrointestinal (GI) conditions (i.e...
  75. BIOLOGICAL STUDIES IN SUICIDAL ADOLESCENT INPATIENTS
    Laurence Greenhill; Fiscal Year: 2000
    ..The study will recruit MDD attempters (N-53) who are consecutively referred for hospitalization because of a suicide attempt during the previous 12 months and age-matched (N-53) MDD non-attempters...
  76. Naltrexone for Bipolar Disorder and Alcohol Dependence
    E Sherwood Brown; Fiscal Year: 2006
    ..When present in patients with bipolar disorder, alcohol dependence is associated with increased rates of hospitalization, poor outcome during hospitalization, violence towards self and others, and non-adherence to bipolar disorder ..
  77. Use of a Nitric Oxide-Loaded Gel to Improve Healing Outcomes of Burn Injuries
    William R Kelce; Fiscal Year: 2012
    ..In the United States, 450,000 experience burns requiring hospitalization and 3,500 of these lead to fatal outcomes...
  78. NURSING HOME CARE AT THE END-OF-LIFE: COST & QUALITY
    Vincent Mor; Fiscal Year: 2000
    ..Research available on management of pain in NHs suggests unmanaged pain is prevalent. Hospitalization research reveals that NH care at the end of life is fragmented and fraught with avoidable hazards and that ..
  79. Evaluating an emergency department observation syncope protocol for older adults
    Benjamin C Sun; Fiscal Year: 2010
    ..within 48 hours, and approximately 50% of patients do not have an identified cause of syncope after their hospitalization. The implementation of an expedited and standardized Emergency Department Observation Syncope Protocol (EDOSP)..
  80. ALCOHOL USE AND INJURY OUTCOMES IN THE US ARMY
    Nicole Bell; Fiscal Year: 2002
    ..HRA data will be linked by social security numbers to hospitalization, death, accident and disability data...
  81. ALCOHOL USE AND INJURY OUTCOMES IN THE US ARMY
    Nicole Bell; Fiscal Year: 2000
    ..HRA data will be linked by social security numbers to hospitalization, death, accident and disability data...
  82. Neurohormonal Blockade and Outcomes in Diastolic Heart Failure
    Ali Ahmed; Fiscal Year: 2010
    ..Most of these patients are older adults, for whom HF is the leading (~1 million per year) cause for hospitalization. The overall prognosis of diastolic HF is very similar to systolic HF or HF with moderately to severely ..
  83. The Epidemiology of Hospitalized Postpartum Depression
    David Savitz; Fiscal Year: 2009
    ..provided by applicant): The epidemiological characteristics of severe postpartum depression requiring hospitalization have not been described...
  84. Predictors of Hospital-Acquired Urinary Tract-Related Bloodstream Infection
    Sanjay Saint; Fiscal Year: 2009
    ..factors, particularly those specific to the time-dependent elements that may impact prognosis during hospitalization. Therefore, the ability of clinicians to intercede in a meaningful way has been restricted...
  85. FEEDING STRATEGIES FOR LOW BIRTH WEIGHT INFANTS
    RICHARD SCHANLER; Fiscal Year: 2000
    ..However, with less morbidity and shorter hospitalization cost becomes less relevant...