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Publications
Bronchiolitis-associated hospitalizations among US children, 1980-1996D K Shay
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 282:1440-6. 1999..Few national estimates exist of the hospitalizations attributable to RSV, and recent advances in prophylaxis warrant an update of these estimates...
Rhythm control versus rate control for atrial fibrillation and heart failureDenis Roy
Montreal Heart Institute and the Université de Montréal, Montreal, QC H1T 1C8, Canada
N Engl J Med 358:2667-77. 2008..However, the benefits and risks of this approach have not been adequately studied...
Skull base osteomyelitis: the effect of comorbid disease on hospitalizationVanessa S Rothholtz
Department of Otolaryngology Head and Neck Surgery, University of California Irvine, Orange, California 92868, USA
Laryngoscope 118:1917-24. 2008..We also provide a more comprehensive evaluation of comorbid disease and severity of illness in this population and describe their effects on the duration and cost of hospital stay...
Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, KenyaWendy P O'Meara
Kenya Medical Research Institute, Centre for Geographic Medicine Research Wellcome Trust Collaborative Program, Kilifi, Kenya Fogarty International Center, National Institutes of Health, Bethesda, MD, USA
Lancet 372:1555-62. 2008..We aimed to assess the epidemiological characteristics of malaria in Kilifi, Kenya, during a period of decreasing transmission intensity...
Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infectionRyan Zarychanski
Department of Internal Medicine, University of Manitoba, CancerCare Manitoba, Winnipeg, Manitoba
CMAJ 182:257-64. 2010..The objective of this study was to identify factors correlated with severity of disease in confirmed cases of pandemic H1N1 influenza...
Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009Seema Jain
Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
N Engl J Med 361:1935-44. 2009..We describe the clinical characteristics of patients who were hospitalized with 2009 H1N1 influenza in the United States from April 2009 to mid-June 2009...
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalizationAlan S Go
Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
N Engl J Med 351:1296-305. 2004..End-stage renal disease substantially increases the risks of death, cardiovascular disease, and use of specialized health care, but the effects of less severe kidney dysfunction on these outcomes are less well defined...
Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in MexicoRogelio Perez-Padilla
National Institute of Respiratory Diseases, Mexico City, Mexico
N Engl J Med 361:680-9. 2009....
Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in CaliforniaJanice K Louie
California Department of Public Health, 850 Marina Bay Pkwy, Richmond, CA 94804, USA
JAMA 302:1896-902. 2009..Pandemic influenza A(H1N1) emerged rapidly in California in April 2009. Preliminary comparisons with seasonal influenza suggest that pandemic 2009 influenza A(H1N1) disproportionately affects younger ages and causes generally mild disease...
Influenza-associated hospitalizations in the United StatesWilliam W Thompson
Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 292:1333-40. 2004..Respiratory viral infections are responsible for a large number of hospitalizations in the United States each year...
Critically Ill patients with 2009 influenza A(H1N1) in MexicoGuillermo Dominguez-Cherit
Division of Pulmonary and Critical Care Dr Domínguez Cherit, Hospital Epidemiology Department, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
JAMA 302:1880-7. 2009..In March 2009, novel 2009 influenza A(H1N1) was first reported in the southwestern United States and Mexico. The population and health care system in Mexico City experienced the first and greatest early burden of critical illness...
Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in ArgentinaRomina Libster
Fundacion INFANT, Buenos Aires
N Engl J Med 362:45-55. 2010..While the Northern Hemisphere experiences the effects of the 2009 pandemic influenza A (H1N1) virus, data from the recent influenza season in the Southern Hemisphere can provide important information on the burden of disease in children...
The severity of pandemic H1N1 influenza in the United States, from April to July 2009: a Bayesian analysisAnne M Presanis
Medical Research Council Biostatistics Unit, Cambridge, United Kingdom
PLoS Med 6:e1000207. 2009..We sought to estimate the probabilities that symptomatic infection would lead to hospitalization, ICU admission, and death by combining data from multiple sources.
Risk factors for hospitalisation and poor outcome with pandemic A/H1N1 influenza: United Kingdom first wave (May-September 2009)J S Nguyen-Van-Tam
Division of Epidemiology and Public Health, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Thorax 65:645-51. 2010..The clinical characteristics of UK patients hospitalised with pandemic H1N1 infection and risk factors for severe outcome are described...
Fine particulate air pollution and its components in association with cause-specific emergency admissionsAntonella Zanobetti
Department of Environmental Health, School of Public Health, Harvard University, Boston, MA, USA
Environ Health 8:58. 2009..We explored whether the association between cause-specific hospital admissions and PM(2.5) was modified by PM(2.5) chemical composition...
The burden of respiratory syncytial virus infection in young childrenCaroline Breese Hall
Department of Pediatrics, The University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
N Engl J Med 360:588-98. 2009..The primary role of respiratory syncytial virus (RSV) in causing infant hospitalizations is well recognized, but the total burden of RSV infection among young children remains poorly defined...
Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional studyAlexander T Cohen
King s College Hospital, London, UK
Lancet 371:387-94. 2008....
Effect of dronedarone on cardiovascular events in atrial fibrillationStefan H Hohnloser
Department of Cardiology, J W Goethe University, Frankfurt, Germany
N Engl J Med 360:668-78. 2009..Dronedarone is a new antiarrhythmic drug that is being developed for the treatment of patients with atrial fibrillation...
Risk of severe outcomes among patients admitted to hospital with pandemic (H1N1) influenzaAlexia Campbell
Centre for Immunization and Respiratory Infectious Diseases, Infectious Disease and Emergency Preparedness Branch, Public Health Agency of Canada, Ottawa, Ontario
CMAJ 182:349-55. 2010....
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation StudyDavid N Juurlink
Department of Medicine University of Toronto, Toronto
N Engl J Med 351:543-51. 2004..Use of angiotensin-converting-enzyme (ACE) inhibitors is also indicated in these patients. However, life-threatening hyperkalemia can occur when these drugs are used together...
Smoke-free legislation and hospitalizations for acute coronary syndromeJill P Pell
University of Glasgow, United Kingdom
N Engl J Med 359:482-91. 2008..However, it is unknown whether the reduction in admissions involved nonsmokers, smokers, or both...
Viral loads and duration of viral shedding in adult patients hospitalized with influenzaNelson Lee
Department of Medicine and Therapeutics, Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
J Infect Dis 200:492-500. 2009..The goal of this study was to characterize viral loads and factors affecting viral clearance in persons with severe influenza...
Contrasting patterns of mortality and hospital admissions during hot weather and heat waves in Greater London, UKR S Kovats
Public and Environmental Health Research Unit, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Occup Environ Med 61:893-8. 2004..Epidemiological research has shown that mortality increases during hot weather and heat waves, but little is known about the effect on non-fatal outcomes in the UK...
Hospitalized patients with 2009 pandemic influenza A (H1N1) virus infection in the United States--September-October 2009Jacek Skarbinski
Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Clin Infect Dis 52:S50-9. 2011....
Pandemic influenza in Canadian children: a summary of hospitalized pediatric casesJulie A Bettinger
Vaccine Evaluation Center, BC Children s Hospital and the University of British Columbia, Vancouver, BC, Canada
Vaccine 28:3180-4. 2010..Close to 50% of children received antiviral medication. Two children died from the infection. The pediatric risk groups affected and course of disease caused by pandemic H1N1 appear similar to seasonal influenza...
Fatalities associated with the 2009 H1N1 influenza A virus in New York cityEllen H Lee
Bureau of Communicable Disease, Division of Disease Control, New York City Department of Health and Mental Hygiene, New York, USA
Clin Infect Dis 50:1498-504. 2010..Among all hospitalized patients, decedents had presented for hospitalization later (median, 3 vs 2 days after illness onset; P < .05) and received oseltamivir later (median, 6...
Food-related illness and death in the United StatesP S Mead
Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 5:607-25. 1999..Overall, foodborne diseases appear to cause more illnesses but fewer deaths than previously estimated...
Rhythm or rate control in atrial fibrillation--Pharmacological Intervention in Atrial Fibrillation (PIAF): a randomised trialS H Hohnloser
JW Goethe University, Frankfurt, Germany
Lancet 356:1789-94. 2000..Restoration and maintenance of sinus rhythm is believed by many physicians to be superior to rate control only. However, there are no prospective data that compare both therapeutic strategies...
The 2006 California heat wave: impacts on hospitalizations and emergency department visitsKim Knowlton
Health and Environment Program, Natural Resources Defense Council, New York, New York 10011 4231, USA
Environ Health Perspect 117:61-7. 2009..Climate models project that heat waves will increase in frequency and severity. Despite many studies of mortality from heat waves, few studies have examined morbidity...
Telemonitoring or structured telephone support programmes for patients with chronic heart failure: systematic review and meta-analysisRobyn A Clark
Division of Health Sciences, University of South Australia, Adelaide, Australia
BMJ 334:942. 2007..To determine whether remote monitoring (structured telephone support or telemonitoring) without regular clinic or home visits improves outcomes for patients with chronic heart failure...
Chronic heart failure: contemporary diagnosis and managementGautam V Ramani
University of Maryland School of Medicine, Baltimore, USA
Mayo Clin Proc 85:180-95. 2010Chronic heart failure (CHF) remains the only cardiovascular disease with an increasing hospitalization burden and an ongoing drain on health care expenditures...
Identification of older hospitalised patients at risk for functional decline, a study to compare the predictive values of three screening instrumentsJita G Hoogerduijn
Faculty of Health Care, Hogeschool Utrecht, University of Applied Science, Utrecht, The Netherlands
J Clin Nurs 19:1219-25. 2010....
Long-term clinical course of patients after termination of ventricular tachyarrhythmia by an implanted defibrillatorArthur J Moss
Cardiology Unit of the Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
Circulation 110:3760-5. 2004..This analysis from the MADIT-II trial database examines the long-term clinical course and subsequent mortality risk of patients after termination of life-threatening ventricular tachyarrhythmias by an ICD...
Incidence and outcomes of acute lung injuryGordon D Rubenfeld
Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle, WA 98104-2499, USA
N Engl J Med 353:1685-93. 2005..6 million hospital days. CONCLUSIONS: Acute lung injury has a substantial impact on public health, with an incidence in the United States that is considerably higher than previous reports have suggested...
Epidemiology of seasonal influenza: use of surveillance data and statistical models to estimate the burden of diseaseWilliam W Thompson
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 194:S82-91. 2006..a 7-component national surveillance system for influenza that includes virologic, influenza-like illness, hospitalization, and mortality data...
Elevated plasma fibrinogen associated with reduced pulmonary function and increased risk of chronic obstructive pulmonary diseaseM Dahl
Department of Clinical Biochemistry, Herlev and Copenhagen University Hospitals, Copenhagen, Denmark
Am J Respir Crit Care Med 164:1008-11. 2001..fibrinogen correlate with pulmonary function and rate of chronic obstructive pulmonary disease (COPD) hospitalization. We measured plasma fibrinogen and forced expiratory volume in 1 s (FEV(1)), and assessed prospectively COPD ..
Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutterBramah N Singh
Cardiology Division, Veterans Affairs Greater Los Angeles Healthcare System and the David Geffen School of Medicine at UCLA, Los Angeles, CA 90073, USA
N Engl J Med 357:987-99. 2007..Dronedarone is a new antiarrhythmic agent pharmacologically related to amiodarone but developed to reduce the risk of side effects...
Clinical and epidemiologic characteristics of children hospitalized with 2009 pandemic H1N1 influenza A infectionSwati Kumar
Medical College of Wisconsin, Pediatric Infectious Diseases, Children s Hospital of Wisconsin, Milwaukee, WI 53201 1997, USA
Pediatr Infect Dis J 29:591-4. 2010..We describe the clinical and epidemiologic characteristics of children and adolescents hospitalized for 2009 H1N1 infections in Milwaukee, Wisconsin from April 2009 to August 2009...
Multimodal strategies to improve surgical outcomeHenrik Kehlet
Department of Surgical Gastroenterology, Hvidovre University Hospital, Hvidovre, Denmark
Am J Surg 183:630-41. 2002..most elective operations will become day surgical procedures or require only 1 to 2 days of postoperative hospitalization. Reorganization of the perioperative team (anesthesiologists, surgeons, nurses, and physical therapists) will ..
Emergency admissions for cardiovascular and respiratory diseases and the chemical composition of fine particle air pollutionRoger D Peng
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Environ Health Perspect 117:957-63. 2009..5) (particulate matter <or= 2.5 microm in aerodynamic diameter) as the indicator. Evidence regarding the toxicity of the chemical components of the PM(2.5) mixture is limited...
Human bocavirus: a novel parvovirus epidemiologically associated with pneumonia requiring hospitalization in ThailandAlicia M Fry
Epidemiology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 195:1038-45. 2007..We detected human bocavirus (HBoV) infection in 4.5% of hospitalized patients with pneumonia in rural Thailand. However, the role of HBoV as a pathogen is unclear...
Synchrony, waves, and spatial hierarchies in the spread of influenzaCecile Viboud
Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
Science 312:447-51. 2006..A simple epidemiological model, based on the gravity formulation, captures the observed increase of influenza spatial synchrony with transmissibility; high transmission allows influenza to spread rapidly beyond local spatial constraints...
Air pollution and emergency admissions in Boston, MAAntonella Zanobetti
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA
J Epidemiol Community Health 60:890-5. 2006..5) is now the particle measure of greatest health and regulatory concern. And little has been published on associations of hospital admissions and PM components...
Complications and outcomes of pandemic 2009 Influenza A (H1N1) virus infection in hospitalized adults: how do they differ from those in seasonal influenza?Nelson Lee
Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Peoples Republic of China
J Infect Dis 203:1739-47. 2011..It is unclear whether pandemic 2009 influenza A (pH1N1) infection caused more significant disease among hospitalized adults than seasonal influenza...
A novel risk factor for a novel virus: obesity and 2009 pandemic influenza A (H1N1)Janice K Louie
Division of Communicable Disease Control, California Department of Public Health, Richmond, California94804, USA
Clin Infect Dis 52:301-12. 2011..many critically ill patients with 2009 pandemic influenza A (H1N1) (2009 H1N1) infection were noted to be obese, but whether obesity, rather than its associated co-morbidities, is an independent risk factor for severe infection is unknown...
A longitudinal study of medication nonadherence and hospitalization risk in schizophreniaMichael R Law
Department of Ambulatory Care and Prevention, Harvard Medical School, and Harvard Pilgrim Health Care, Boston, Mass 02215, USA
J Clin Psychiatry 69:47-53. 2008Previous cross-sectional studies have suggested an association between medication nonadherence and hospitalization for individuals with schizophrenia. However, such analyses typically measure adherence averaged over long time periods...
COPD exacerbations: defining their cause and preventionJadwiga A Wedzicha
Academic Unit of Respiratory Medicine, Royal Free and University College Medical School University College London, UK
Lancet 370:786-96. 2007....
Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failureMichael R Bristow
Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
N Engl J Med 350:2140-50. 2004..in the form of biventricular stimulation with a pacemaker with or without a defibrillator would reduce the risk of death and hospitalization among patients with advanced chronic heart failure and intraventricular conduction delays.
Viral clearance and inflammatory response patterns in adults hospitalized for pandemic 2009 influenza A(H1N1) virus pneumoniaNelson Lee
Department of Medicine and Therapeutics, Prince of Wales Hospital, Hong Kong SAR, China
Antivir Ther 16:237-47. 2011..Little is known about the virological and inflammatory responses of severe pandemic 2009 influenza A(H1N1) virus pneumonia during antiviral treatment...
Comorbidity, hospitalization, and mortality in COPD: results from a longitudinal studyClaudio Terzano
Respiratory Diseases Unit, Department of Cardiovascular and Respiratory Sciences, Sapienza University of Rome, Fondazione E Lorillard Spencer Cenci, Via Casal de Pazzi 16, 00156 Rome, Italy
Lung 188:321-9. 2010We evaluated comorbidity, hospitalization, and mortality in chronic obstructive pulmonary disease (COPD), with special attention to risk factors for frequent hospitalizations (more than three during the follow-up period), and prognostic ..
Venous thromboembolism prophylaxis in acutely ill hospitalized medical patients: findings from the International Medical Prevention Registry on Venous ThromboembolismVictor F Tapson
Division of Pulmonary and Critical Care, Box 31175, Room 351 Bell Building, Duke University Medical Center, Durham, NC 27710, USA
Chest 132:936-45. 2007..Our aim was to characterize the clinical practices for VTE prophylaxis in acutely ill hospitalized medical patients enrolled in the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE)...
Hospital admissions among people 65+ related to multimorbidity, municipal and outpatient careAnna Condelius
Department of Health Sciences, Faculty of Medicine, Lund University, P O Box 157, 221 00 Lund, Sweden
Arch Gerontol Geriatr 46:41-55. 2008..Thus interventions focusing on frequent admissions are needed, and this requires collaboration between outpatient and hospital care...
Selective serotonin reuptake inhibitors provide significant lower re-hospitalization rates in patients recovering from acute coronary syndromes: evidence from a meta-analysisMarianna Mazza
Institute of Psychiatry and Psychology, Catholic University of Sacred Heart of Rome, Via Ugo De Carolis 48, Rome, Italy
J Psychopharmacol 24:1785-92. 2010..05). Treatment with SSRIs in patients recovering from ACS is associated with significant lower re-hospitalization rates...
Hospitalization for pneumonia among individuals with and without HIV infection, 1995-2007: a Danish population-based, nationwide cohort studyOle S Sogaard
Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
Clin Infect Dis 47:1345-53. 2008..We compared incidence rates of pneumonia among individuals with and without HIV infection and explored risk factors for pneumonia in the HIV-infected population...
Inpatient rehabilitation specifically designed for geriatric patients: systematic review and meta-analysis of randomised controlled trialsStefan Bachmann
Department of Geriatrics, Inselspital, University of Bern Hospital, Freiburgstrasse 10, CH 3010 Bern, Switzerland
BMJ 340:c1718. 2010..To assess the effects of inpatient rehabilitation specifically designed for geriatric patients compared with usual care on functional status, admissions to nursing homes, and mortality...
Depression as a predictor of mortality and hospitalization among hemodialysis patients in the United States and EuropeAntonio Alberto Lopes
Department of Medicine, Federal University of Bahia, Brazil
Kidney Int 62:199-207. 2002..We investigated whether risk of mortality and rate of hospitalization may be predicted from physician-diagnosed depression and patients' self-reports of depressive symptoms.
Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1) diseaseOliver W Morgan
Division of Emerging Infections and Surveillance Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 5:e9694. 2010..We assessed whether obesity is a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1), independent of chronic medical conditions considered by the ..
Bacteremia in febrile Malawian children: clinical and microbiologic featuresA L Walsh
Wellcome Trust Research Laboratories, University of Malawi, Blantyre
Pediatr Infect Dis J 19:312-8. 2000..There are no published data for the incidence or etiology of childhood bacteremia in Malawi. We describe the clinical and microbiologic features of children admitted to hospital from whom blood cultures yielded bacterial pathogens...
Outcomes of adults hospitalised with severe influenzaN Lee
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
Thorax 65:510-5. 2010..The aim of this study was to investigate factors affecting clinical outcomes of adults hospitalised with severe seasonal influenza...
Changing malaria intervention coverage, transmission and hospitalization in KenyaEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, 00100 GPO, Nairobi, Kenya
Malar J 9:285. 2010..Whether this transition is directly related to the scaling of intervention coverage remains a moot point...
BronchiolitisRosalind L Smyth
Division of Child Health, School of Reproductive and Developmental Medicine, University of Liverpool, Alder Hey Children s Hospital, Liverpool L12 2AP, UK
Lancet 368:312-22. 2006..Careful mapping of the inflammatory pathways in the pathogenesis of bronchiolitis should lead to development of new therapies to alleviate symptoms...
Treatment for rheumatoid arthritis and the risk of hospitalization for pneumonia: associations with prednisone, disease-modifying antirheumatic drugs, and anti-tumor necrosis factor therapyFrederick Wolfe
National Data Bank for Rheumatic Diseases and University of Kansas School of Medicine, Wichita, Kansas 67214, USA
Arthritis Rheum 54:628-34. 2006..This study was undertaken to determine the rate and predictors of hospitalization for pneumonia and the extent to which specific RA treatments increase pneumonia risk.
Incidence of adverse drug reactions in paediatric in/out-patients: a systematic review and meta-analysis of prospective studiesP Impicciatore
Academic Division of Child Health (Nottingham University) Derbyshire Children's Hospital, Derby, UK
Br J Clin Pharmacol 52:77-83. 2001..Further, methodologically sound drug surveillance studies are necessary for an effective promotion of a safer use of drugs in children...
Intrathoracic impedance monitoring in patients with heart failure: correlation with fluid status and feasibility of early warning preceding hospitalizationCheuk Man Yu
Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
Circulation 112:841-8. 2005..system capable of measuring intrathoracic impedance to identify potential fluid overload before heart failure hospitalization and to determine the correlation between intrathoracic impedance and standard measures of fluid status during ..
Drug-related problems in hospitals: a review of the recent literatureAnita Krähenbühl Melcher
Hospital Pharmacy, Regionalspital Emmental, Burgdorf, Switzerland
Drug Saf 30:379-407. 2007....
Which drugs cause preventable admissions to hospital? A systematic reviewR L Howard
Nottingham Primary Care Research Partnership, Broxtowe and Hucknall PCT, Hucknall Health Centre, Nottingham, UK
Br J Clin Pharmacol 63:136-47. 2007....
Cardiac resynchronization in chronic heart failureWilliam T Abraham
Division of Cardiovascular Medicine, University of Kentucky College of Medicine, Lexington 40536 0284, USA
N Engl J Med 346:1845-53. 2002..We conducted a double-blind trial to evaluate this therapeutic approach...
Cardiac-resynchronization therapy for mild-to-moderate heart failureAnthony S L Tang
Island Medical Program, University of British Columbia, Vancouver, Canada
N Engl J Med 363:2385-95. 2010..Most of these patients are candidates for an implantable cardioverter-defibrillator (ICD). We evaluated whether adding CRT to an ICD and optimal medical therapy might reduce mortality and morbidity among such patients...
Novel influenza A(H1N1) in a pediatric health care facility in New York City during the first wave of the 2009 pandemicYolanda Miroballi
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Arch Pediatr Adolesc Med 164:24-30. 2010..To describe the burden of care experienced by our pediatric health care facility in New York, New York, from May 3, 2009, to July 31, 2009, during the novel influenza A(H1N1) pandemic that began in spring 2009...
Outbreak of pandemic influenza A (H1N1-2009) in Singapore, May to September 2009Jeffery L Cutter
Communicable Diseases Division, Ministry of Health, Singapore
Ann Acad Med Singapore 39:273-10. 2010..The World Health Organization declared the fi rst influenza pandemic of the 21st century on 11 June 2009...
Eplerenone in patients with systolic heart failure and mild symptomsFaiez Zannad
INSERM, Centre d Investigation Clinique 9501 and Unité 961, and the Department of Cardiology, Nancy University, Nancy, France
N Engl J Med 364:11-21. 2011..We evaluated the effects of eplerenone in patients with chronic systolic heart failure and mild symptoms...
Reduction in acute gastroenteritis hospitalizations among US children after introduction of rotavirus vaccine: analysis of hospital discharge data from 18 US statesAaron T Curns
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30329, USA
J Infect Dis 201:1617-24. 2010In 2006, RotaTeq (RV5) was recommended for routine vaccination of United States (US) infants. We compared hospitalization rates for acute gastroenteritis among US children aged <5 years during pre-RV5 rotavirus seasons from 2000 ..
Combined heart failure device diagnostics identify patients at higher risk of subsequent heart failure hospitalizations: results from PARTNERS HF (Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With HearDavid J Whellan
Department of Medicine, Jefferson Medical College, 925 Chestnut Street, Philadelphia, PA 19107, USA
J Am Coll Cardiol 55:1803-10. 2010..We sought to determine the utility of combined heart failure (HF) device diagnostic information to predict clinical deterioration of HF in patients with systolic left ventricular dysfunction...
Respiratory viruses in bronchoalveolar lavage: a hospital-based cohort study in adultsJ Garbino
University Hospitals of Geneva, Switzerland
Thorax 64:399-404. 2009..A study was performed to investigate the association between positive viral detection and respiratory infection in an at-risk population...
Cost of hospitalization for preterm and low birth weight infants in the United StatesRebecca B Russell
March of Dimes, 1275 Mamaroneck Ave, White Plains, NY 10605, USA
Pediatrics 120:e1-9. 2007..The objective of this study was to estimate national hospital costs for infant admissions that are associated with preterm birth/low birth weight...
Relative impact of risk factors for deep vein thrombosis and pulmonary embolism: a population-based studyJohn A Heit
Hematology Research, Stabile 660, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Arch Intern Med 162:1245-8. 2002..of venous thromboembolism in the community could be attributed to institutionalization (current or recent hospitalization or nursing home residence)...
Sensitivity of routine system for reporting patient safety incidents in an NHS hospital: retrospective patient case note reviewAli Baba Akbari Sari
Department of Health Sciences, University of York, York YO10 5DD
BMJ 334:79. 2007..To evaluate the performance of a routine incident reporting system in identifying patient safety incidents...
Effects of digoxin on morbidity and mortality in diastolic heart failure: the ancillary digitalis investigation group trialAli Ahmed
University of Alabama at Birmingham, 1530 3rd Ave S, CH 19, Suite 219, Birmingham AL 35294 2041, USA
Circulation 114:397-403. 2006..Although digoxin was tested in an appreciable number of diastolic heart failure patients in the Digitalis Investigation Group ancillary trial, detailed findings from this important study have not previously been published...
Diabetes is an independent predictor of survival 17 years after myocardial infarction: follow-up of the TRACE registryThomas Kümler
Department of Cardiology, Rigshopitalet University Hospital, Blegdamsvej, Copenhagen, Denmark
Cardiovasc Diabetol 9:22. 2010..The aim of this study was to systematically evaluate the development of diabetes as an independent long-term prognostic factor after myocardial infarction...
Population prevalence, incidence, and predictors of atrial fibrillation in the Renfrew/Paisley studyS Stewart
Clinical Research Initiative in Heart Failure, Wolfson Building (Level 3, University of Glasgow, Glasgow G12 8QQ, UK
Heart 86:516-21. 2001..These findings have important implications for the prevention of AF...
Impact of a triage liaison physician on emergency department overcrowding and throughput: a randomized controlled trialBrian R Holroyd
Department of Emergency Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
Acad Emerg Med 14:702-8. 2007..Triage liaison physicians (TLPs) have been employed in overcrowded emergency departments (EDs); however, their effectiveness remains unclear...
A statewide system of trauma care in Victoria: effect on patient survivalPeter A Cameron
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic, Australia
Med J Aust 189:546-50. 2008..To determine whether the statewide system of trauma care introduced in 2000 has resulted in improved survival for all major trauma patients in Victoria...
Alternative endpoints for mortality in studies of patients with atrial fibrillation: the AFFIRM study experienceD George Wyse
Libin Cardiovascular Institute of Alberta, University of Calgary, Canada
Heart Rhythm 1:531-7. 2004OBJECTIVES: The purpose of this study was to examine possible alternatives for death, particularly hospitalization for cardiovascular reasons (CV hospitalization), as an endpoint in studies of atrial fibrillation (AF) using the Atrial ..
Cardiopulmonary hospitalizations during influenza season in adults and adolescents with advanced HIV infectionKathleen M Neuzil
Department of Medicine, University of Washington and the Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
J Acquir Immune Defic Syndr 34:304-7. 2003..From 1995 through 1999, cardiopulmonary hospitalization rates in HIV-infected patients declined by 53% and death rates declined by 77%...
Severity of 2009 pandemic influenza A (H1N1) virus infection in pregnant womenAndreea A Creanga
Epidemic Intelligence Service Program, Office of Workforce and Career Development, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA 30341 3717, USA
Obstet Gynecol 115:717-26. 2010..To examine 2009 H1N1 influenza illness severity and the effect of antiviral treatment on the severity of illness among pregnant women...
The European cardiac resynchronization therapy surveyKenneth Dickstein
Stavanger University Hospital, Stavanger, Norway
Eur Heart J 30:2450-60. 2009..The primary aim of this survey is to describe current European practice associated with CRT implantations...
A systematic review of predictors and screening instruments to identify older hospitalized patients at risk for functional declineJita G Hoogerduijn
Research and Development Fellow, Faculty Chair for Chronically ill, Faculty of Health Care, Hogeschool Utrecht, Utrecht, The Netherlands
J Clin Nurs 16:46-57. 2007..The predictors of functional decline are initially considered and, subsequently, the characteristics and psychometric qualities of existing screening instruments are investigated...
Trends in childhood asthma: prevalence, health care utilization, and mortalityLara J Akinbami
Infant and Child Health Studies Branch, National Center for Health Statistics, Centers for Disease Control and Prevention, Bethesda, Maryland, USA
Pediatrics 110:315-22. 2002..Our objective was to use national data to produce a comprehensive description of trends in childhood asthma prevalence, health care utilization, and mortality to assess changes in the disease burden among US children...
A novel group of rhinoviruses is associated with asthma hospitalizationsE Kathryn Miller
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232 9500, USA
J Allergy Clin Immunol 123:98-104.e1. 2009..Although recent studies have identified new group C human rhinoviruses (HRVCs), their spectrum of pediatric disease is unknown...
Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccineTimo Vesikari
University of Tampere Medical School, Tampere, Finland
N Engl J Med 354:23-33. 2006..The risk of intussusception was similar in vaccine and placebo recipients. (ClinicalTrials.gov number, NCT00090233.)..
Respiratory syncytial virus, human bocavirus and rhinovirus bronchiolitis in infantsF Midulla
Department of Pediatrics, Sapienza University of Rome, Viale Regina Elena 324, 00165 Rome, Italy
Arch Dis Child 95:35-41. 2010..To investigate the prevalence of 14 viruses in infants with bronchiolitis and to study demographic and clinical differences in those with respiratory syncytial virus (RSV), human bocavirus (hBoV) and rhinovirus (RV) infection...
Factors associated with mortality after an asthma admission: a national United Kingdom database analysisLouise Watson
Phimap, Adelphi Mill, Bollington, Cheshire SK10 5JB, UK
Respir Med 101:1659-64. 2007..This study aims to report these factors in addition to season of event for the years 2000-2005 to provide data regarding asthma burden in the in-patient hospital setting...
Epidemiology of hospitalized burn patients in Shandong Province: 2001-2005Feng Yongqiang
Department of Burn and Plastic Surgery, Shandong Provincial Hospital, Shandong University, Jinan 250021, China
J Burn Care Res 28:468-73. 2007The aim of the article was to describe the epidemiology of burn injuries requiring hospitalization at Shandong Provincial Hospital and to provide information necessary for the design and implementation of effective prevention programs...
Intensive care unit admissions in the Jos University Teaching HospitalE S Isamade
Department of Anaesthesia, Jos University Teaching Hospital, Jos
Niger J Clin Pract 10:156-61. 2007..To determine the pattern of admissions to the intensive care unit (ICU) of the Jos University Teaching Hospital (JUTH), a tertiary level referral hospital...
Hospitalizations for anaphylaxis in Florida: epidemiologic analysis of a population-based datasetZuber D Mulla
Division of Epidemiology, The University of Texas School of Public Health at Houston, Tex, USA
Int Arch Allergy Immunol 144:128-36. 2007..Previous epidemiologic studies of anaphylaxis have been single-institution investigations. The objective of this study was to determine the annual hospital discharge rate and risk factors for anaphylaxis outcomes throughout Florida...
Burden of encephalitis-associated hospitalizations in the United States, 1988-1997Nino Khetsuriani
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 35:175-82. 2002..6% of hospitalizations. Rates of encephalitis-associated hospitalization were highest for children <1 year old and persons > or =65 years old...
Assessment of the future resources and needs for hospitalization in Hong Kong SAR (Special Administrative District)Paul S F Yip
Department of Statistics and Actuarial Sciences, The University of Hong Kong, Hong Kong
Int J Health Plann Manage 17:113-22. 2002..To study the 'compression of morbidity' theory in the Hong Kong SAR by analysing the age and gender-specific hospitalization rates and the expected length of stay per patient for the period 1996-2000...
[Epidemiology of femur fracture and characteristics of hospital care in Lazio]F Sperati
Facoltutà di Scienze Statistiche, Universittà degli Studi di Roma La Sapienza
Ann Ig 19:49-61. 2007..Direct standardization (rate x 1000) and logistic regression analysis (OR, 95% CI) were performed. Overall hospitalization rate in elderly was 7.5%o (10.l%o females vs. 3.9%0 males). 12...
Epidemiology of hospitalized burns patients in TaiwanWu-Chien Chien
Graduate Institute of Life Sciences, National Defense Medical Center, National Defense University, ROC, Taipei, Taiwan
Burns 29:582-8. 2003..are the most common agents responsible for scalds. Prevention programs for reducing the risk of burn injuries during cooking and eating are required, especially for parents with young children...
Epidemiology of salmonellosis in California, 1990-1999: morbidity, mortality, and hospitalization costsR T Trevejo
Disease Investigations and Surveillance Branch, Division of Communicable Disease Control, California Department of Health Services, Sacramento, CA 94234-7320, USA
Am J Epidemiol 157:48-57. 2003..costs of nontyphoidal salmonellosis in California from 1990 through 1999 are described using surveillance, hospitalization, and death data...
The occurrence of asymptomatic and symptomatic simple hepatic cysts. A prospective, hospital-based studyT B Larssen
Department of Radiology, Haukeland University Hospital, Bergen, Norway
Clin Radiol 60:1026-9. 2005..To examine the prevalence of asymptomatic and symptomatic liver cysts in a university hospital patient population using modern US equipment...
Research Grants
- Myocardial Salvage With a Novel Reperfusion TherapyCONSTANCE WILSON; Fiscal Year: 2005..the heart following angioplasty procedures and coronary artery bypass graft surgery can affect the length of hospitalization, cost of hospitalization, functional capacity of the patient at discharge, and may ultimately contribute to ..
- Medicare Part D Plan Generosity & Dual-Eligible Nursing Home ResidentsHaiden Huskamp; Fiscal Year: 2009..care pharmacy in combination with data on health outcomes from the Minimum Data Set (MDS) and Medicare Part A hospitalization claims for the period 2005-2008 (one year before and three years after Part D implementation)...
- Pain and Hypoxia in Premature NeonatesDANILYN ANGELES; Fiscal Year: 2009..admitted to the neonatal intensive care unit (NICU) require up to several hundred procedures during their hospitalization. Many of these are tissue damaging procedures (TDPs) that cause pain...
- Standardized Rehabilitation for ICU Patients with Acute Respiratory FailurePeter E Morris; Fiscal Year: 2010..dyspnea, depression, and reduced health-related quality of life, all of which may contribute to prolonged hospitalization and increased costs. Patients with ARF average 15 hospital days with median costs of $30,000...
- Pain and Hypoxia in Premature NeonatesDANILYN MAG AKAT ANGELES; Fiscal Year: 2010..admitted to the neonatal intensive care unit (NICU) require up to several hundred procedures during their hospitalization. Many of these are tissue damaging procedures (TDPs) that cause pain...
- Transforming PCI Informed Consent into an Evidence-based Decision-making ToolJohn A Spertus; Fiscal Year: 2010..Major bleeding events also result in a 3-4 day increase in length of stay,11 in turn increasing hospitalization costs by $6,000-8,000...
- Transforming PCI Informed Consent into an Evidence-based Decision-making ToolJohn Spertus; Fiscal Year: 2009..Major bleeding events also result in a 3-4 day increase in length of stay,11 in turn increasing hospitalization costs by $6,000-8,000...
- Medicare Part D Plan Generosity & Dual-Eligible Nursing Home ResidentsHaiden A Huskamp; Fiscal Year: 2010..care pharmacy in combination with data on health outcomes from the Minimum Data Set (MDS) and Medicare Part A hospitalization claims for the period 2005-2008 (one year before and three years after Part D implementation)...
- Project CLEAR - Changing Lives by Eradicating Antibiotic ResistanceSusan S Huang; Fiscal Year: 2010..Identification of an effective strategy to reduce MRSA infection and hospitalization would be a major advancement in clinical care...
- Standardized Rehabilitation for ICU Patients with Acute Respiratory FailurePeter Morris; Fiscal Year: 2009..dyspnea, depression, and reduced health-related quality of life, all of which may contribute to prolonged hospitalization and increased costs. Patients with ARF average 15 hospital days with median costs of $30,000...
- Design of New AntimicrobialsRobert S Hodges; Fiscal Year: 2010..Consequently, the cost of treating nosocomial infections through extended hospitalization and increasingly aggressive therapy has risen to an estimated $30 billion in the U.S...
- A CDSS to Translate Pressure Ulcer Prediction and Prevention to Home Health CareSandra Bergquist Beringer; Fiscal Year: 2007..pain, social isolation and many develop complications such as osteomyelitis or bacteremia that require hospitalization. Overall costs for treatment are $9.1 to $11.6 billion per year...
- Design of New AntimicrobialsRobert Hodges; Fiscal Year: 2009..Consequently, the cost of treating nosocomial infections through extended hospitalization and increasingly aggressive therapy has risen to an estimated $30 billion in the U.S...
- Outcomes and Costs Associated with Frequency of Physician-Patient Visits on HemodAreef Ishani; Fiscal Year: 2010..We hypothesize that greater physician-patient visit frequency is associated with a reduced patient hospitalization and mortality rate, greater achievement of dialysis clinical performance targets, greater utilization of ..
- NC/OFQ analogs as ORL1 agonists to promote gut motilityMARK FINDEIS; Fiscal Year: 2005..Clinically, POI has serious impact on patient morbidity, causing patient discomfort and prolongation of hospitalization by 3 to 10 days...
- Cytokines and Sympathetic Activation in Heart FailureRobert Felder; Fiscal Year: 2009Heart failure is the most common reason for hospitalization in the United States among those older than 65 years, and this statistic is expected to grow as the population ages...
- Pathogenesis of cognitive/neurologic deficits in central nervous system malariaChandy John; Fiscal Year: 2009..6% of children >5 years of age who survive CM have cognitive deficits 6 months after hospitalization. However, the effects of CM on cognition in younger children have not been prospectively characterized, and ..
- Impact of Length of Stay and Number of Home Nursing Visits on HospitalizationMELISSA O apos CONNOR; Fiscal Year: 2010..b>Hospitalization costs incurred by Medicare recipients exceeded 471 billion dollars in 2007...
- Physiologic Responses to Simulated Care Activities in Older Surgical PatientsColleen Casey; Fiscal Year: 2007The importance of preserving physical function during hospitalization, especially for adults aged 65 and older, is so well acknowledged that clinical care activities such as turning and ambulating are part of routine hospital ward care...
- Effects of Hospitalists in Medicare DataDavid Meltzer; Fiscal Year: 2007b>Hospitalization for acute general medical conditions is a common and often pivotal event for older Americans...
- Effectiveness and Cost-Effectiveness of Peer Mentors in Reducing Hospital UseLarry Davidson; Fiscal Year: 2010..Data will be collected during the index hospitalization and at 3 and 9 months after discharge...
- STICH Trial-Statistical and Data Coordinatiing CenterKerry Lee; Fiscal Year: 2007..surgical ventricular restoration (SVR) to a more normal LV size improves survival free of subsequent hospitalization for cardiac cause in comparison to CABG alone...
- The long-term consequences of postoperative acute kidney injuryAreef Ishani; Fiscal Year: 2007..of AKI are well defined and included, an increased hospital length of stay, an increased cost of hospitalization, and increased risk of short- term mortality...
- Naltrexone for Bipolar Disorder and Alcohol DependenceE Sherwood Brown; Fiscal Year: 2006..When present in patients with bipolar disorder, alcohol dependence is associated with increased rates of hospitalization, poor outcome during hospitalization, violence towards self and others, and non-adherence to bipolar disorder ..
- ALCOHOL USE AND INJURY OUTCOMES IN THE US ARMYNicole Bell; Fiscal Year: 2002..HRA data will be linked by social security numbers to hospitalization, death, accident and disability data...
- Coping Skills Training in Heart Failure: Outcomes and MechanismsAndrew Sherwood; Fiscal Year: 2010..therapy, symptom instability and clinical deterioration are common and lead to frequent physician visits, hospitalization, and ultimately death...
- Neurohormonal Blockade and Outcomes in Diastolic Heart FailureAli Ahmed; Fiscal Year: 2010..Most of these patients are older adults, for whom HF is the leading (~1 million per year) cause for hospitalization. The overall prognosis of diastolic HF is very similar to systolic HF or HF with moderately to severely ..
- Fatty Acids and Heart Failure in the Physicians' Health StudyLuc Djousse; Fiscal Year: 2009Heart failure (HF) is the leading cause of hospitalization among elderly people in the US with an annual incidence rate of 550,000 cases. Despite advances in medical and surgical treatment, mortality after the onset of HF remains high...
