diskectomy

Summary

Summary: Excision, in part or whole, of an intervertebral disk. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.

Top Publications

  1. ncbi Polyetheretherketone as a biomaterial for spinal applications
    Jeffrey M Toth
    Department of Orthopaedic Surgery, Medical College of Wisconsin, 9200 W Wisconsin Ave, Box 26099, Milwaukee, WI 53226 0099, USA
    Biomaterials 27:324-34. 2006
  2. ncbi Cervical interbody fusion is enhanced by allogeneic mesenchymal precursor cells in an ovine model
    Tony Goldschlager
    Monash Immunology and Stem Cell Laboratories, Department of Surgery, Monash University, Victoria, Australia
    Spine (Phila Pa 1976) 36:615-23. 2011
  3. pmc The NEtherlands Cervical Kinematics (NECK) trial. Cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in the treatment of cervical disc herniation; a double-blind randomised multicenter study
    Mark P Arts
    Department of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands
    BMC Musculoskelet Disord 11:122. 2010
  4. ncbi Prospective, randomized, multicenter study of cervical arthroplasty: 269 patients from the Kineflex|C artificial disc investigational device exemption study with a minimum 2-year follow-up: clinical article
    Domagoj Coric
    Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina, USA
    J Neurosurg Spine 15:348-58. 2011
  5. pmc Factors affecting sagittal malalignment due to cage subsidence in standalone cage assisted anterior cervical fusion
    Pavel Barsa
    Department of Neurosurgery, Regional Hospital of Liberec, Husova str 10, 46063 Liberec, Czech Republic
    Eur Spine J 16:1395-400. 2007
  6. ncbi Comparison of one-level posterior lumbar interbody fusion performed with a minimally invasive approach or a traditional open approach
    Yung Park
    Department of Orthopedic Surgery, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea
    Spine (Phila Pa 1976) 32:537-43. 2007
  7. ncbi Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft
    Michael G Kaiser
    Emory Clinic, Department of Neurosurgery, Emory University, Atlanta, Georgia 30322, USA
    Neurosurgery 50:229-36; discussion 236-8. 2002
  8. ncbi Lumbar total disc replacement from an extreme lateral approach: clinical experience with a minimum of 2 years' follow-up
    Luiz Pimenta
    Minimally Invasive and Reconstructive Spine Surgery, Instituto de Patologia da Coluna, Sao Paulo, Brazil
    J Neurosurg Spine 14:38-45. 2011
  9. ncbi Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervi
    Daniel Murrey
    OrthoCarolina Spine Center, Charlotte, NC 28207, USA
    Spine J 9:275-86. 2009
  10. ncbi Anterior approaches to fusion of the cervical spine: a metaanalysis of fusion rates
    Justin F Fraser
    Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
    J Neurosurg Spine 6:298-303. 2007

Research Grants

Detail Information

Publications302 found, 100 shown here

  1. ncbi Polyetheretherketone as a biomaterial for spinal applications
    Jeffrey M Toth
    Department of Orthopaedic Surgery, Medical College of Wisconsin, 9200 W Wisconsin Ave, Box 26099, Milwaukee, WI 53226 0099, USA
    Biomaterials 27:324-34. 2006
    ..Based on these results, the polymeric biomaterial PEEK may be a useful biomaterial for interbody fusion cages due to the polymer's increased radiolucency and decreased stiffness...
  2. ncbi Cervical interbody fusion is enhanced by allogeneic mesenchymal precursor cells in an ovine model
    Tony Goldschlager
    Monash Immunology and Stem Cell Laboratories, Department of Surgery, Monash University, Victoria, Australia
    Spine (Phila Pa 1976) 36:615-23. 2011
    ..An experimental study using a sheep cervical spine interbody fusion model...
  3. pmc The NEtherlands Cervical Kinematics (NECK) trial. Cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in the treatment of cervical disc herniation; a double-blind randomised multicenter study
    Mark P Arts
    Department of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands
    BMC Musculoskelet Disord 11:122. 2010
    ..We present the design of the NECK trial, a randomised study on cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in patients with cervical disc herniation...
  4. ncbi Prospective, randomized, multicenter study of cervical arthroplasty: 269 patients from the Kineflex|C artificial disc investigational device exemption study with a minimum 2-year follow-up: clinical article
    Domagoj Coric
    Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina, USA
    J Neurosurg Spine 15:348-58. 2011
    ..This prospective, randomized, multicenter study evaluates the safety and efficacy of a new metal-on-metal CTDR implant (Kineflex|C) by comparing it with ACDF in the treatment of single-level spondylosis with radiculopathy...
  5. pmc Factors affecting sagittal malalignment due to cage subsidence in standalone cage assisted anterior cervical fusion
    Pavel Barsa
    Department of Neurosurgery, Regional Hospital of Liberec, Husova str 10, 46063 Liberec, Czech Republic
    Eur Spine J 16:1395-400. 2007
    ..The significance of implant subsidence in acceleration of degenerative changes in adjacent segments remains to be evaluated during a longer follow-up...
  6. ncbi Comparison of one-level posterior lumbar interbody fusion performed with a minimally invasive approach or a traditional open approach
    Yung Park
    Department of Orthopedic Surgery, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea
    Spine (Phila Pa 1976) 32:537-43. 2007
    ..Prospective cohort study...
  7. ncbi Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft
    Michael G Kaiser
    Emory Clinic, Department of Neurosurgery, Emory University, Atlanta, Georgia 30322, USA
    Neurosurgery 50:229-36; discussion 236-8. 2002
    ..The purpose of this study was to evaluate the efficacy of anterior cervical plating for fusion enhancement after one- and two-level ACDF with cortical allograft...
  8. ncbi Lumbar total disc replacement from an extreme lateral approach: clinical experience with a minimum of 2 years' follow-up
    Luiz Pimenta
    Minimally Invasive and Reconstructive Spine Surgery, Instituto de Patologia da Coluna, Sao Paulo, Brazil
    J Neurosurg Spine 14:38-45. 2011
    ..In this study, the authors attempted to quantify the clinical and radiographic outcomes of a lateral approach to lumbar TDR from a prospective, single-center experience...
  9. ncbi Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervi
    Daniel Murrey
    OrthoCarolina Spine Center, Charlotte, NC 28207, USA
    Spine J 9:275-86. 2009
    ..Cervical total disc replacement (TDR) is intended to address radicular pain and preserve functional motion between two vertebral bodies in patients with symptomatic cervical disc disease (SCDD)...
  10. ncbi Anterior approaches to fusion of the cervical spine: a metaanalysis of fusion rates
    Justin F Fraser
    Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
    J Neurosurg Spine 6:298-303. 2007
    ..The authors conducted a metaanalysis of studies published after 1990 in which fusion rates achieved with each procedure were reported for patients with degenerative disease at one, two, and three disc levels...
  11. ncbi Assessment of adjacent-segment disease in patients treated with cervical fusion or arthroplasty: a prospective 2-year study
    James T Robertson
    Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Neurosurg Spine 3:417-23. 2005
    ....
  12. ncbi Two-year outcome after lumbar microdiscectomy versus microscopic sequestrectomy: part 1: evaluation of clinical outcome
    Martin Barth
    Department of Neurosurgery, University Hospital Mannheim, Medical Faculty Mannheim of the Ruprecht Karls University of Heidelberg, Germany
    Spine (Phila Pa 1976) 33:265-72. 2008
    ..Single-center randomized prospective study at a university hospital...
  13. ncbi A novel minimally invasive presacral approach and instrumentation technique for anterior L5-S1 intervertebral discectomy and fusion: technical description and case presentations
    Nicola Marotta
    Division of Neurosurgery, University of California at Los Angeles, California, USA
    Neurosurg Focus 20:E9. 2006
    ..The purpose of this technical note is to demonstrate a novel surgical approach, technique, and instrumentation system for the treatment of L5-S1 instability in degenerative disc disease and spondylolisthesis...
  14. ncbi Anterior cervical discectomy and fusion associated complications
    Kostas N Fountas
    Department of Neurosurgery, Medical Center of Central Georgia, Mercer University, School of Medicine, Macon, GA, USA
    Spine (Phila Pa 1976) 32:2310-7. 2007
    ..Retrospective review study with literature review...
  15. ncbi The efficacy of the synthetic interbody cage and Grafton for anterior cervical fusion
    Hyun Woong Park
    Department of Neurosurgery, Chonnam National University Hospital and Medical School, Gwangju, Korea
    Spine (Phila Pa 1976) 34:E591-5. 2009
    ..Prospective study of 31 patients who underwent anterior cervical fusion...
  16. ncbi A population-based study of reoperations after back surgery
    R W Hu
    Musculoskeletal Health Status Working Group, Division of Orthopaedics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Spine (Phila Pa 1976) 22:2265-70; discussion 2271. 1997
    ..More extensive surgery does not prevent nor predispose a patient to the need for further surgery...
  17. ncbi Results of cervical arthroplasty compared with anterior discectomy and fusion: four-year clinical outcomes in a prospective, randomized controlled trial
    Rick C Sasso
    Indiana Spine Group, 8402 Harcourt Road, Suite 400, Indianapolis, IN 46260, USA
    J Bone Joint Surg Am 93:1684-92. 2011
    ..The purpose of this study was to evaluate the midterm safety and effectiveness of the Bryan disc as an alternative to arthrodesis following anterior cervical discectomy...
  18. ncbi A systematic review of randomized trials on the effect of cervical disc arthroplasty on reducing adjacent-level degeneration
    Ricardo Vieira Botelho
    Neurosurgical Service, Hospital do Servidor Público do Estado de São Paulo, Sao Paulo, Brazil
    Neurosurg Focus 28:E5. 2010
    ..Since 2002, cervical disc arthroplasty has been established as an alternative to fusion. The objective of this study was to review data concerning the role of cervical arthroplasty in reducing adjacent-level degeneration...
  19. ncbi An evidence-based review of the literature on the consequences of conservative versus aggressive discectomy for the treatment of primary disc herniation with radiculopathy
    William C Watters
    Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Spine J 9:240-57. 2009
    ..It remains unknown whether aggressive disc removal with curettage versus conservative removal of a disc fragment with little disc invasion provides a better outcome for the treatment of lumbar disc herniation with radiculopathy...
  20. ncbi Does anterior plating maintain cervical lordosis versus conventional fusion techniques? A retrospective analysis of patients receiving single-level fusions
    Stephan J Troyanovich
    Life Chiropractic College West, Hayward, California, USA
    J Spinal Disord Tech 15:69-74. 2002
    ..In comparison, the conventional method resulted in a net loss of overall lordosis and segmental lordosis at the surgical site...
  21. ncbi Cages augmented with mineralized collagen and platelet-rich plasma as an osteoconductive/inductive combination for interbody fusion
    Matti Scholz
    Center for Spinal Surgery and Neurotraumatology, Traumaclinic Frankfurt Main, Germany
    Spine (Phila Pa 1976) 35:740-6. 2010
    ..After anterior cervical discectomy, fusion was radiologically, biomechanically, and histologically assessed in a sheep spine fusion model...
  22. ncbi Video-assisted thoracoscopic surgery for thoracic disc disease: Classification and outcome study of 100 consecutive cases with a 2-year minimum follow-up period
    Neel Anand
    Cedars Sinai Institute for Spinal Disorders, Cedars Sinai Medical Center, Los Angeles, California, USA
    Spine (Phila Pa 1976) 27:871-9. 2002
    ..Prospectively collected data from regular clinical follow-up evaluations were tabulated, analyzed, reviewed using a patient self-reported questionnaire...
  23. pmc Does minimally invasive lumbar disc surgery result in less muscle injury than conventional surgery? A randomized controlled trial
    Mark Arts
    Department of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands
    Eur Spine J 20:51-7. 2011
    ..Postoperative evaluation of CPK and the multifidus muscle showed similar results in both groups, although patients who underwent tubular discectomy reported more low-back pain during the first year after surgery...
  24. ncbi Anterior corpectomy with iliac bone fusion or discectomy with interbody titanium cage fusion for multilevel cervical degenerated disc disease
    Shiuh Lin Hwang
    Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Spinal Disord Tech 20:565-70. 2007
    ..Clinical and radiologic study evaluating the outcome after anterior corpectomy with iliac bone fusion compared with discectomy with interbody titanium cage fusion for multilevel cervical degenerated disc disease...
  25. ncbi Incidence of dysphagia after anterior cervical spine surgery: a prospective study
    Rajesh Bazaz
    Spine Institute and Department of Orthopaedic Surgery, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Spine (Phila Pa 1976) 27:2453-8. 2002
    ..A prospective longitudinal study was conducted to evaluate dysphagia after anterior cervical spine surgery...
  26. ncbi Rehabilitation after lumbar disc surgery: an update Cochrane review
    Raymond W J G Ostelo
    EMGO Institute VU University Medical Centre, Amsterdam, The Netherlands
    Spine (Phila Pa 1976) 34:1839-48. 2009
    ..Cochrane systematic review of randomized controlled trials...
  27. ncbi Three-level anterior cervical discectomy and fusion with plate fixation: radiographic and clinical results
    Elias C Papadopoulos
    Hospital for Special Surgery, New York, NY 10021, USA
    Spine (Phila Pa 1976) 31:897-902. 2006
    ..Retrospective review of patients with cervical spondylosis treated with 3-level anterior cervical discectomy and fusion with plate fixation...
  28. ncbi The Cochrane review of surgery for lumbar disc prolapse and degenerative lumbar spondylosis
    J N Gibson
    University Department of Orthopaedic Surgery, Princess Margaret Rose Orthopaedic Hospital, Edinburgh, Scotland
    Spine (Phila Pa 1976) 24:1820-32. 1999
    ..A Cochrane review of randomized controlled trials...
  29. ncbi Recurrent lumbar disk herniation
    Joseph K Lee
    Department of Orthopaedic Durgery, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, USA
    J Am Acad Orthop Surg 18:327-37. 2010
    Recurrent lumbar disk herniation is the most common complication following primary open diskectomy. It is defined as recurrent back and/or leg pain after a definite pain-free period lasting at least 6 months from initial surgery...
  30. pmc Comparison of postural control in unilateral stance between healthy controls and lumbar discectomy patients with and without pain
    Katie Bouche
    Rehabilitation Sciences and Physiotherapy, Ghent University Hospital, Ghent, Belgium
    Eur Spine J 15:423-32. 2006
    ..In addition, the influence of the extent of disc resection (unilateral/bilateral removal) and the side of operation on static balance control were investigated...
  31. ncbi Prospective multiple outcomes study of outpatient lumbar microdiscectomy: should 75 to 80% success rates be the norm?
    Harold L Asch
    Buffalo Neurosurgery Group, New York 14224, USA
    J Neurosurg 96:34-44. 2002
    ..The authors use the methodology and data derived from their study to evaluate critically the relevance of these two categories of success rates...
  32. ncbi Subsidence after anterior cervical inter-body fusion. A randomized prospective clinical trial
    Erich Kast
    Department of Neurosurgery, Kantonsspital Winterthur, Brauerstrasse 15, CH 8401, Winterthur, Switzerland
    Neurosurg Rev 32:207-14; discussion 214. 2009
    ..Although there was no significant difference in a short-term clinical result between the two treatment groups, we recommend the use of cages which preserve the determined segmental height and lordosis...
  33. ncbi Outcomes of interbody fusion cages used in 1 and 2-levels anterior cervical discectomy and fusion: titanium cages versus polyetheretherketone (PEEK) cages
    Chi Chien Niu
    Department of Orthopedics Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan
    J Spinal Disord Tech 23:310-6. 2010
    ..A prospective study was performed in case with cervical spondylosis who underwent anterior cervical discectomy and fusion (ACDF) with titanium or polyetheretherketone (PEEK) cages...
  34. ncbi Preliminary experience using a polyetheretherketone (PEEK) cage in the treatment of cervical disc disease
    Der Yang Cho
    Department of Neurosurgery, China Medical College Hospital, Taichung, Taiwan, Republic of China
    Neurosurgery 51:1343-49; discussion 1349-50. 2002
    ..We investigated the effectiveness of a new material, polyetheretherketone (PEEK), in a spinal cage used in performing cervical spinal fusion for the correction of cervical kyphosis...
  35. pmc Clinical experience in cell-based therapeutics: intervention and outcome
    Hans Joerg Meisel
    Bergmannstrost, Neurochirurgie klinik, Merseburger Strasse 165, 06112, Halle, Saale, Germany
    Eur Spine J 15:S397-405. 2006
    ....
  36. ncbi Posterior foraminotomy or anterior discectomy with polymethyl methacrylate interbody stabilization for cervical soft disc disease: results in 292 patients with monoradiculopathy
    Marcus C Korinth
    Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany
    Spine (Phila Pa 1976) 31:1207-14; discussion 1215-6. 2006
    ..Retrospective study of patients who underwent either ventral microdiscectomy and polymethyl methacrylate (PMMA) interbody stabilization or posterior foraminotomy for the treatment of cervical monoradiculopathy caused by soft disc disease...
  37. ncbi Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft
    Douglas B Moreland
    Buffalo Neurosurgery Group, 550 Orchard Park Road, Buffalo, NY 14224, USA
    Spine J 4:184-91; discussion 191. 2004
    ..One of these devices is the titanium Rabea cage (Signus, Alzenau, Germany) [correction]. There are no peer-reviewed objective reports on the use of these cages in cervical discectomy...
  38. ncbi Is autograft the gold standard in achieving radiographic fusion in one-level anterior cervical discectomy and fusion with rigid anterior plate fixation?
    Dino Samartzis
    Department of Orthopaedic Surgery, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Spine (Phila Pa 1976) 30:1756-61. 2005
    ..A review of 66 consecutive patients at a single institution who underwent one-level anterior cervical discectomy and fusion (ACDF) with rigid anterior plate fixation with allograft or autograft...
  39. ncbi Posterolateral endoscopic excision for lumbar disc herniation: Surgical technique, outcome, and complications in 307 consecutive cases
    Anthony Tung Yeung
    Arizona Orthopedic Surgeons, Phoenix, Arizona, USA
    Spine (Phila Pa 1976) 27:722-31. 2002
    ..A retrospective review involving 307 consecutive cases of lumbar disc herniation managed by posterolateral endoscopic discectomy was conducted...
  40. ncbi Removal of a protruded thoracic disc using microsurgical endoscopy. A new technique
    D Rosenthal
    Department of Neurosurgery, University Hospital, Frankfurt am Main Germany
    Spine (Phila Pa 1976) 19:1087-91. 1994
    ..It may shorten bed confinement and allow early return to active life. Application of this technique in other areas is being studied...
  41. pmc A systematic review of bio-psychosocial risk factors for an unfavourable outcome after lumbar disc surgery
    Jasper J den Boer
    Department of Physical Therapy, UMC Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur Spine J 15:527-36. 2006
    ..However, further systematic and methodologically high quality research is required, particularly for those predictors that can be positively influenced by multidisciplinary interventions...
  42. pmc Subsidence and nonunion after anterior cervical interbody fusion using a stand-alone polyetheretherketone (PEEK) cage
    Jae Jun Yang
    Depatment of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea
    Clin Orthop Surg 3:16-23. 2011
    ..The purposes of the present study are to evaluate the subsidence and nonunion that occurred after anterior cervical discectomy and fusion using a stand-alone intervertebral cage and to analyze the risk factors for the complications...
  43. ncbi Height of cervical foramina after anterior discectomy and implantation of a carbon fiber cage
    R H Bartels
    Department of Orthopedic Surgery, Center for Surgery of the Spine and Craniospinal Junction, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands
    J Neurosurg 95:40-2. 2001
    ..The authors evaluate the effects of implantation of a carbon fiber cage after anterior cervical discectomy (ACD) on the height of the foramen and the angulation between endplates of the disc space...
  44. ncbi Vascular injury complicating lumbar disc surgery. A systematic review
    S Papadoulas
    Department of Surgery, Vascular Surgery Unit, University Hospital of Patras, Patras, Greece
    Eur J Vasc Endovasc Surg 24:189-95. 2002
    ..to review the literature concerning the early and late vascular complications of lumbar disc surgery...
  45. ncbi Risk of multiple reoperations after lumbar discectomy: a population-based study
    Heikki Osterman
    ORTON Orthopaedic Hospital, Invalid Foundation, Helsinki, Finland
    Spine (Phila Pa 1976) 28:621-7. 2003
    ..Retrospective follow-up study of patients undergoing multiple (two or more) reoperations after initial lumbar discectomy using an administrative database...
  46. ncbi Efficacy of anterior cervical fusion: comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts
    Yu Cheng Chou
    Division of Functional Neuroscience, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    J Clin Neurosci 15:1240-5. 2008
    ..3% in group B, and 84.85% in group C. The fusion rates after 1 year in groups A, B, and C were 46.51%, 100% and 100%, respectively. The PEEK cage is a viable alternative to autogenous tricortical bone grafts in anterior cervical fusion...
  47. ncbi Mesh cage reconstruction with autologous cancellous graft in anterior cervical discectomy and fusion
    Christopher K Kepler
    Spine and Scoliosis Service, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
    J Spinal Disord Tech 23:328-32. 2010
    ..Retrospective case series...
  48. ncbi Long-term results after anterior cervical discectomy and fusion with allograft and plating: a 5- to 11-year radiologic and clinical follow-up study
    Wai Mun Yue
    Study performed at the Columbia Spine Centre, Columbia, MO, USA
    Spine (Phila Pa 1976) 30:2138-44. 2005
    ..A retrospective review...
  49. ncbi Multilevel cervical fusion without plates, screws or autogenous iliac crest bone graft
    Mehmet Nusret Demircan
    GATA Haydarpasa Training Hospital, Department of Neurosurgery, Istanbul, Turkey
    J Clin Neurosci 14:723-8. 2007
    ....
  50. ncbi Radiographic and clinical outcomes following single-level anterior cervical discectomy and allograft fusion without plate placement or cervical collar
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Box 800212, Charlottesville, Virginia 22908, USA
    J Neurosurg Spine 8:420-8. 2008
    ..This paper examines a single-surgeon experience with single-level ACDF without use of plates or hard collars in patients with degenerative spondylosis in whom allograft was used as the fusion material...
  51. ncbi A comparison of changes over time in cervical foraminal height after tricortical iliac graft or polyetheretherketone cage placement following anterior discectomy
    Suat E Celik
    Department of Neurosurgery, Beyoglu State Hospital, Istanbul, Turkey
    J Neurosurg Spine 6:10-6. 2007
    ..To their knowledge, this prospective study is the first in which foraminal height changes over time are compared following the placement of a tricortical graft or a polyetheretherketone (PEEK) cage...
  52. pmc Five-year outcome of stand-alone fusion using carbon cages in cervical disc arthrosis
    N Marotta
    Department of Neurosurgery, University of Rome Sapienza, Rome, Italy
    Eur Spine J 20:S8-12. 2011
    ..In the opinion, pseudoarthrosis is caused by malpositioning of the carbon fiber cage...
  53. ncbi Effects of a cervical disc prosthesis on segmental and cervical spine alignment
    Gwynedd E Pickett
    Division of Neurosurgery, Department of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada
    Neurosurg Focus 17:E5. 2004
    ..The impact of cervical arthroplasty on sagittal alignment of the FSU needs to be addressed, together with its effect on overall sagittal balance of the cervical spine...
  54. ncbi Standard open microdiscectomy versus minimal access trocar microdiscectomy: results of a prospective randomized study
    Yu Mi Ryang
    Department of Neurosurgery, University Hospital Rheinisch Westfäl Technische Hochschule Aachen, Aachen University, Aachen, Germany
    Neurosurgery 62:174-81; discussion 181-2. 2008
    ..5 mm trocar system for minimal access to the spine...
  55. pmc Cervical disc herniation and cervical spondylosis surgically treated by Cloward procedure: a 10-year-minimum follow-up study
    Cesare Faldini
    Department of Orthopaedic Surgery, Istituto Ortopedico Rizzoli, University of Bologna, Via G Pupilli 1, 40136, Bologna, Italy
    J Orthop Traumatol 11:99-103. 2010
    ....
  56. ncbi Discectomy versus discectomy with fusion versus discectomy with fusion and instrumentation: a prospective randomized study
    Jing Cheng Xie
    University of Calgary Spine Program, Foothills Hospital and Medical Centre, Calgary, Canada
    Neurosurgery 61:107-16; discussion 116-7. 2007
    ....
  57. ncbi Pseudoarthrosis of the cervical spine: a comparison of radiographic diagnostic measures
    Lisa K Cannada
    Department of Orthopaedics, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Spine (Phila Pa 1976) 28:46-51. 2003
    ..A retrospective review was conducted...
  58. pmc Reoperations after first lumbar disc herniation surgery; a special interest on residives during a 5-year follow-up
    Arja Hakkinen
    Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, Jyvaskyla, Finland
    BMC Musculoskelet Disord 8:2. 2007
    ....
  59. pmc Microendoscopic lumbar discectomy versus open surgery: an intraoperative EMG study
    U Schick
    Neurological Surgery Clinic, University of Leipzig, Germany
    Eur Spine J 11:20-6. 2002
    ..The study showed that microendoscopic discectomy allows a smaller incision and less tissue trauma with comparable visualization of the nerve structures than does open surgery...
  60. ncbi Recurrent lumbar disc herniation after discectomy: outcome of repeat discectomy
    Li Yang Dai
    Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Second Medical University, Shanghai 200092, China
    Surg Neurol 64:226-31; discussion 231. 2005
    ..The purpose of the current study was to address the outcome in the patients who had recurrent disc herniation treated with repeat discectomy and to identify the factors that may influence the outcome...
  61. ncbi Treatment of multilevel cervical fusion with cages
    Der Yang Cho
    Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan, Republic of China
    Surg Neurol 62:378-85, discussion 385-6. 2004
    ..In this study, we try to use cages to replace plate function in multilevel cervical fusion...
  62. ncbi Anterior cervical fusion using a polyetheretherketone cage containing a bovine xenograftp: three to five-year follow-up
    Chang Jung Chiang
    Department of Orthopedic Surgery, Taipei City Hospital, Taipei, Taiwan
    Spine (Phila Pa 1976) 33:2524-428. 2008
    ..Retrospective review of an anterior polyetheretherketone (PEEK) cage incorporated with a bovine xenograft to treat disorders of the cervical disc...
  63. ncbi Assessment of the minimum clinically important difference in pain, disability, and quality of life after anterior cervical discectomy and fusion: clinical article
    Scott L Parker
    Department of Neurological Surgery and Vanderbilt Spinal Column Surgical Quality and Outcomes Research Laboratory, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Neurosurg Spine 18:154-60. 2013
    ....
  64. ncbi [Partial nucleotomy of the ovine disc as an in vivo model for disc degeneration]
    E Guder
    Hals Nasen Ohrenheilkunde, Universitätsklinikum Rostock
    Z Orthop Unfall 147:52-8. 2009
    ..The aim of this study was to develop a suitable animal model for the clinical situation of progressive disc degeneration after microsurgical nucleotomy...
  65. ncbi Minimally invasive lumbar spinal fusion
    Jason C Eck
    Department of Orthopaedic Surgery, Memorial Hospital, York, PA, USA
    J Am Acad Orthop Surg 15:321-9. 2007
    ..There is a steep learning curve associated with minimally invasive techniques, and surgeons should not expect to master them in the first several cases...
  66. pmc Microdiscectomy compared with standard discectomy: an old problem revisited with new outcome measures within the framework of a spine surgical registry
    F Porchet
    Department of Neurosurgery, Spine Center, Schulthess Klinik, Lengghalde 2, 8008 Zurich, Switzerland
    Eur Spine J 18:360-6. 2009
    ..There was no clinically relevant difference in outcome after lumbar disc excision dependent on the use of the microscope. The decision to use the microscope should rest with the surgeon...
  67. ncbi One-level one-sided lumbar disc surgery with and without microscopic assistance: 1-year outcome in 114 consecutive patients
    Kudret Tureyen
    Department of Neurosurgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey
    J Neurosurg 99:247-50. 2003
    ..The aim of this study was to compare the outcomes following macrodiscectomy and microsurgery for one-level one-sided lumbar disc excision...
  68. ncbi Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: a randomized controlled trial
    Laszlo Vutskits
    Division of Anesthesiology, University Hospitals of Geneva, 24, Rue Micheli du Crest, CH 1211, Geneva 14, Switzerland
    Neurochem Res 33:1325-31. 2008
    ..These data suggest that in males undergoing elective minor surgery, BDNF plasma concentrations show a specific pattern that is influenced by the anesthetic technique and, possibly, by the duration of surgery...
  69. ncbi Endoscopic thoracic microdiscectomy
    Rod J Oskouian
    Department of Neurological Surgery, University of Virginia Health Systems, Charlottesville, Virginia, USA
    J Neurosurg Spine 3:459-64. 2005
    ..The purpose of this clinical study was to evaluate prospectively surgical and neurological outcomes after endoscopic thoracic disc surgery...
  70. pmc Repair, regenerative and supportive therapies of the annulus fibrosus: achievements and challenges
    Johannes Leendert Bron
    Department of Orthopaedic Surgery, VU University Medical Center, Amsterdam, The Netherlands
    Eur Spine J 18:301-13. 2009
    ..In the current review, the requirements, achievements and challenges in this quickly emerging field of research are discussed...
  71. ncbi Visceral and vascular complications resulting from anterior lumbar interbody fusion
    V Rajaraman
    Division of Neurosurgery, New Jersey Medical School, Newark 07013, USA
    J Neurosurg 91:60-4. 1999
    ..The causes, strategies for their avoidance, and the clinical course of these complications are also discussed...
  72. ncbi A 10-year follow-up of the outcome of lumbar microdiscectomy
    G F Findlay
    Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    Spine (Phila Pa 1976) 23:1168-71. 1998
    ..Patient satisfaction with the results of microdiscectomy 10 years later was high. CONCLUSIONS: Lumbar microdiscectomy achieves a high level of initial success, and this positive outcome is maintained at a 10-year follow-up...
  73. pmc Higher risk of dural tears and recurrent herniation with lumbar micro-endoscopic discectomy
    Marco Teli
    Department of Spinal Surgery, Galeazzi Orthopaedic Institute, Via Galeazzi 4, 20161 Milan, Italy
    Eur Spine J 19:443-50. 2010
    ..In conclusion, outcome measures are equivalent 2 years following lumbar discectomy with micro-endoscopy, microscopy or open technique, but severe complications are more likely and costs higher with micro-endoscopy...
  74. ncbi Long-term outcome after microendoscopic diskectomy for lumbar disk herniation: a prospective clinical study with a 5-year follow-up
    Roberto Casal-Moro
    Department of Orthopaedics, University Hospital of Vigo, Vigo, Spain
    Neurosurgery 68:1568-75; discussion 1575. 2011
    Several authors have reported results obtained with the microendoscopic diskectomy (MED) technique, but the long-term outcome has not been described...
  75. ncbi Microendoscopic lumbar discectomy: technical note
    Mick J Perez-Cruet
    Chicago Institute for Neurosurgery and Neuroresearch, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    Neurosurgery 51:S129-36. 2002
    ..Since then, thousands of cases have been successfully performed at more than 500 institutions. This article discusses the technical aspects of this procedure and presents a consecutive case series...
  76. ncbi Safety and effectiveness of bone allografts in anterior cervical discectomy and fusion surgery
    Larry E Miller
    Miller Scientific Consulting, Inc, Biltmore Lake, NC, USA
    Spine (Phila Pa 1976) 36:2045-50. 2011
    ..Systematic review...
  77. pmc Late-onset post-diskectomy tuberculosis at the same operated lumbar level: case report and review of literature
    Iraj Lotfinia
    Department of Neurosurgery, Tabriz University of Medical Science, Tabriz, Iran
    Eur Spine J 19:S226-32. 2010
    Late post-diskectomy tuberculous spondylodiskitis at the operated level is an extremely rare phenomenon...
  78. ncbi Nightmare of lumbar diskectomy: aorta laceration
    Siu Leung Yip
    Department of Orthopaedics and Traumatology, Kwong Wah Hospital, Hong Kong
    Spine (Phila Pa 1976) 36:E1758-60. 2011
    ..Case report...
  79. pmc Clinical outcomes of patients with lumbar disc herniation, selected for one-level open-discectomy and microdiscectomy
    Kotryna Veresciagina
    Clinic of Neurosurgery, Kaunas University of Medicine Hospital, Eiveniu 2, 50009 Kaunas, Lithuania
    Eur Spine J 19:1450-8. 2010
    ..Regardless of persisted minor pain in both areas, it remained greater in the low back than in the leg, which should be held for beneficial to decompressive surgery...
  80. ncbi Clinical and radiological results following cervical arthroplasty
    D H Yoon
    Department of Neurosurgery, Yonsei University, College of Medicine, Seoul, Korea
    Acta Neurochir (Wien) 148:943-50. 2006
    ..This was a retrospective study of clinical and radiological results of cervical arthroplasty using the Bryan cervical disc prosthesis to evaluate the efficacy of arthroplasty in clinical applications...
  81. ncbi Delayed diagnosis of vascular injuries during lumbar discectomy
    J L Hanouz
    Department of Anesthesiology and Surgical Intensive Care, CHRU of Caen, France
    J Clin Anesth 12:64-6. 2000
    ..An emergent laparotomy was performed to repair vascular injuries. The delayed symptoms, use of medical antishock trousers, and implications for anesthetists are discussed...
  82. ncbi Systematic review and meta-analysis of randomized controlled trials: comparison of total disk replacement with anterior cervical decompression and fusion
    Lin Yu
    Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People s Republic of China
    Orthopedics 34:e651-8. 2011
    ..evaluate whether there is a beneficial clinical effect of total disk replacement compared with anterior cervical diskectomy and fusion for the treatment of single-level symptomatic cervical disk disease...
  83. ncbi Sagittal alignment after Bryan cervical arthroplasty
    Rick C Sasso
    Indiana Spine Group, Indiana University School of Medicine, Indianapolis 46260, USA
    Spine (Phila Pa 1976) 36:991-6. 2011
    ..Prospective, randomized, Food and Drug Administration Investigational Device Exemption trial from one study site...
  84. ncbi Discectomy strategies for lumbar disc herniation: results of the LAPDOG trial
    Stephen J Haines
    Department of Neurological Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Clin Neurosci 9:411-7. 2002
    ..Such evidence should be required by patients to whom such procedures are proposed and those who are asked to pay for them...
  85. ncbi Early active training after lumbar discectomy. A prospective, randomized, and controlled study
    G Kjellby Wendt
    Department of Orthopaedics, Sahlgrenska University Hospital, Ostra, Gothenburg, Sweden
    Spine (Phila Pa 1976) 23:2345-51. 1998
    ..At 2 years' follow-up, more patients were satisfied with the result of the operation. The early active treatment program is recommended...
  86. ncbi Non-fusion rates in anterior cervical discectomy and implantation of empty polyetheretherketone cages
    Ioannis Pechlivanis
    Department of Neurosurgery, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany
    Spine (Phila Pa 1976) 36:15-20. 2011
    ..A prospective analysis...
  87. ncbi Iliac artery injury during lumbar microdiscectomy
    Zbigniew Karwacki
    Department of Neuroanaesthesiology, Medical University of Gdansk
    Anestezjol Intens Ter 42:24-6. 2010
    ..Accidental laceration of major abdominal vessels during lumbar disc surgery is a relatively rare complication that requires rapid diagnosis and management...
  88. pmc Comparison of a minimally invasive procedure versus standard microscopic discotomy: a prospective randomised controlled clinical trial
    Jörg Franke
    Department of Orthopaedic Surgery, Otto von Guericke University of Magdeburg, Magdeburg, Germany
    Eur Spine J 18:992-1000. 2009
    ....
  89. ncbi Radiographic PEEK double-lucency finding after anterior cervical discectomy and fusion with local autograft and PEEK spacer: a preliminary study
    Leslie C Hellbusch
    Department of Surgery Neurosurgery, Nebraska Medical Center, Omaha, Nebraska, USA
    J Neurosurg Spine 16:248-50. 2012
    ..The authors conclude that the radiolucent feature of the PEEK cage, which produces the image finding PEEK double lucency, aids in the determination of fusion...
  90. ncbi The incidence of adjacent segment disease requiring surgery after anterior cervical diskectomy and fusion: estimation using an 11-year comprehensive nationwide database in Taiwan
    Jau Ching Wu
    Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
    Neurosurgery 70:594-601. 2012
    The incidence of symptomatic adjacent segment disease (ASD) after anterior cervical diskectomy and fusion (ACDF) was reported as 2.9%/y in a previous cohort of 374 patients...
  91. ncbi [Polymethylmethacrylate (PMMA) in anterior cervical spine surgery - current situation in Germany]
    J Schroder
    Klinik und Poliklinik fur Neurochirurgie, Universitatsklinikum, Westfalische Wilhelms Universitat Munster
    Zentralbl Neurochir 62:33-6. 2001
    ..33% per year). - In conclusion PMMA is still the most widely used spacer material after anterior cervical discectomy in Germany. An increased complication rate in comparison with other implants could not be observed...
  92. pmc Biomechanical study of a hat type cervical intervertebral fusion cage
    Yu Tong Gu
    Department of Orthopaedics, Zhongshan Hospital of Fudan corrected University, Shanghai, 200032 corrected People s Republic of China
    Int Orthop 31:101-5. 2007
    ..Volume-related stiffness of all cages was higher than that of iliac bone graft. The Harms cage was highest in volume-related stiffness in all directions. The HCIFC can provide enough primary stability for cervical intervertebral fusion...
  93. ncbi Surgical treatment of dysphagia after anterior cervical interbody fusion
    Guy R Fogel
    Houston Spine Surgery, 5225 Katy Freeway, Suite 600, Houston, TX 77007, USA
    Spine J 5:140-4. 2005
    ..A surgical treatment of dysphagia after ACIF has not been reported...
  94. ncbi Micro-endoscopic-discectomy (MED) for far lateral disc herniation in the lumbar spine. Technical note
    P Cervellini
    Department of Neurosurgery, Vicenza Hospital, Vicenza, Italy
    Acta Neurochir Suppl 92:99-101. 2005
    ..Extraforaminal disc herniation can be diagnosed with the aid of CT scan and MRI. The minimally invasive surgical treatment via the micro-endoscopic far lateral approach, in our initial experience, has a high rate of succes...
  95. pmc Prevertebral soft tissue swelling after anterior cervical discectomy and fusion with plate fixation
    K S Suk
    Department of Orthopaedic Surgery, College of Medicine, Kyung Hee University, 1 Heogi dong, Dongdamun Ku, Seoul, South Korea
    Int Orthop 30:290-4. 2006
    ..1%). In conclusion, in this prospective study of 87 patients fused at one or two levels in the cervical spine peak prevertebral soft tissue swelling was observed on the second and third days after the surgery...
  96. ncbi Use of a polymethylmethacrylate cervical cage in the treatment of single-level cervical disc disease
    Jyi Feng Chen
    Department of Neurosurgery, Chang Gung University and Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Neurosurg Spine 3:24-8. 2005
    ..To achieve cervical interbody fusion, the authors designed a modified PMMA cervical cage that they filled with spongy bone for the treatment of single-level cervical disc herniation...
  97. ncbi Airway changes after anterior cervical discectomy and fusion
    Shane A Andrew
    Mount Clemens General Hospital, Michigan State University Statewide Campus System, Mount Clemens, MI, USA
    J Spinal Disord Tech 20:577-81. 2007
    ..To date no published data exist in the English literature upon which to judge symptomatic patients (experiencing postoperative airway distress) radiographically...
  98. pmc Effects of a cervical disc prosthesis on maintaining sagittal alignment of the functional spinal unit and overall sagittal balance of the cervical spine
    Seok Woo Kim
    International Spine Center, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, South Korea
    Eur Spine J 17:20-9. 2008
    ..The Bryan disc preserves motion of the FSU. Although the preoperative lordosis (or kyphosis) of the FSU could not always be maintained during the follow-up period, the overall sagittal balance of the cervical spine was usually preserved...
  99. ncbi Dysphonia and dysphagia following the anterior approach to the cervical spine
    C P Winslow
    Department of Otolaryngology Head and Neck Surgery, Oregon Health Sciences University, Portland, USA
    Arch Otolaryngol Head Neck Surg 127:51-5. 2001
    ..Despite functional morbidity and legal implications, the incidence and etiologic factors of these complications have not been adequately elucidated...
  100. ncbi Minimally invasive far lateral microendoscopic discectomy for extraforaminal disc herniation at the lumbosacral junction: cadaveric dissection and technical case report
    John E O'Toole
    Department of Neurosurgery, Rush University Medical Center, 1725 W Harrison Street, Chicago, IL 60612, USA
    Spine J 7:414-21. 2007
    ..Reports specifically describing minimally invasive surgical approaches to lumbosacral ELDHs are lacking...
  101. ncbi Prognostic role of depression after lumbar disc surgery
    L Arpino
    Department of Neurosurgery, Second University of Naples, Naples, Italy
    Neurol Sci 25:145-7. 2004
    ..In agreement with the literature, our results confirm the negative role of depression in outcome after lumbar disc surgery. We emphasize the consideration of psychological factors in the management of lumbar disc herniation...

Research Grants9

  1. 2006 Summer Bioengineering Conference
    Vijay Goel; Fiscal Year: 2006
    ..This should help create the necessary work force of varied interests in the health care field. [unreadable] [unreadable] [unreadable]..
  2. IN SITU LIGATION FOR DETECTION OF SPECIFIC DNA DAMAGE
    David Baskin; Fiscal Year: 2001
    ..It, therefore, can be used in molecular and cell biology research, as well as by clinicians in many fields, including pathology oncology, cardiology and the clinical neurosciences. ..
  3. Development of a Spinal Intervertebral Disc Prosthesis
    GLENN BUTTERMANN; Fiscal Year: 2003
    ..The objective of Phase I is to demonstrate that the device restores normal spine biomechanics (range of motion and stiffness) and is durable in fatigue testing. ..
  4. Tissue Engineering Utilizing BMP Gene Therapy
    GREGORY HELM; Fiscal Year: 2004
    ....
  5. Functional Health CAT in Diabetes
    Carolyn Schwartz; Fiscal Year: 2004
    ..abstract_text> ..
  6. Individual Differences in Pain Modulation as Predictors of Post-Surgical Pain
    Robert Edwards; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  7. Incidence & Outcomes of SSI After Breast Cancer Surgery
    Margaret Olsen; Fiscal Year: 2008
    ....
  8. Vascular Healing with VEGF-Collagen Binding Chimera
    Luke Brewster; Fiscal Year: 2005
    ..Future promise for VEGFCBD may apply to intimal healing, surface endothelialization, and capillarization of and engineered tissues. ..
  9. Catastrophizing and Pain in Rheumatoid Arthritis
    Robert Edwards; Fiscal Year: 2008
    ..abstract_text> ..