diskectomy

Summary

Summary: Excision, in part or whole, of an intervertebral disk. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.

Top Publications

  1. pmc Anterior cervical discectomy with fusion in patients with cervical disc degeneration: a prospective outcome study of 258 patients (181 fused with autologous bone graft and 77 fused with a PEEK cage)
    Bjarne Lied
    Department of Neurosurgery Rikshospitalet, Oslo University Hospital, N 0027 Oslo, Norway
    BMC Surg 10:10. 2010
  2. doi Prospective, randomized, multicenter study of cervical arthroplasty: 269 patients from the Kineflex|C artificial disc investigational device exemption study with a minimum 2-year follow-up: clinical article
    Domagoj Coric
    Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina, USA
    J Neurosurg Spine 15:348-58. 2011
  3. pmc Factors affecting sagittal malalignment due to cage subsidence in standalone cage assisted anterior cervical fusion
    Pavel Barsa
    Department of Neurosurgery, Regional Hospital of Liberec, Husova str 10, 46063 Liberec, Czech Republic
    Eur Spine J 16:1395-400. 2007
  4. ncbi Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft
    Michael G Kaiser
    Emory Clinic, Department of Neurosurgery, Emory University, Atlanta, Georgia 30322, USA
    Neurosurgery 50:229-36; discussion 236-8. 2002
  5. doi Lumbar total disc replacement from an extreme lateral approach: clinical experience with a minimum of 2 years' follow-up
    Luiz Pimenta
    Minimally Invasive and Reconstructive Spine Surgery, Instituto de Patologia da Coluna, Sao Paulo, Brazil
    J Neurosurg Spine 14:38-45. 2011
  6. ncbi Anterior cervical discectomy and fusion associated complications
    Kostas N Fountas
    Department of Neurosurgery, Medical Center of Central Georgia, Mercer University, School of Medicine, Macon, GA, USA
    Spine (Phila Pa 1976) 32:2310-7. 2007
  7. doi Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervi
    Daniel Murrey
    OrthoCarolina Spine Center, Charlotte, NC 28207, USA
    Spine J 9:275-86. 2009
  8. ncbi Anterior approaches to fusion of the cervical spine: a metaanalysis of fusion rates
    Justin F Fraser
    Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
    J Neurosurg Spine 6:298-303. 2007
  9. ncbi Outcome after lumbar sequestrectomy compared with microdiscectomy: a prospective randomized study
    Claudius Thome
    Department of Neurosurgery, University Hospital Mannheim, Germany
    J Neurosurg Spine 2:271-8. 2005
  10. ncbi Assessment of adjacent-segment disease in patients treated with cervical fusion or arthroplasty: a prospective 2-year study
    James T Robertson
    Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Neurosurg Spine 3:417-23. 2005

Detail Information

Publications279 found, 100 shown here

  1. pmc Anterior cervical discectomy with fusion in patients with cervical disc degeneration: a prospective outcome study of 258 patients (181 fused with autologous bone graft and 77 fused with a PEEK cage)
    Bjarne Lied
    Department of Neurosurgery Rikshospitalet, Oslo University Hospital, N 0027 Oslo, Norway
    BMC Surg 10:10. 2010
    ....
  2. doi Prospective, randomized, multicenter study of cervical arthroplasty: 269 patients from the Kineflex|C artificial disc investigational device exemption study with a minimum 2-year follow-up: clinical article
    Domagoj Coric
    Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina, USA
    J Neurosurg Spine 15:348-58. 2011
    ..This prospective, randomized, multicenter study evaluates the safety and efficacy of a new metal-on-metal CTDR implant (Kineflex|C) by comparing it with ACDF in the treatment of single-level spondylosis with radiculopathy...
  3. pmc Factors affecting sagittal malalignment due to cage subsidence in standalone cage assisted anterior cervical fusion
    Pavel Barsa
    Department of Neurosurgery, Regional Hospital of Liberec, Husova str 10, 46063 Liberec, Czech Republic
    Eur Spine J 16:1395-400. 2007
    ..The significance of implant subsidence in acceleration of degenerative changes in adjacent segments remains to be evaluated during a longer follow-up...
  4. ncbi Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft
    Michael G Kaiser
    Emory Clinic, Department of Neurosurgery, Emory University, Atlanta, Georgia 30322, USA
    Neurosurgery 50:229-36; discussion 236-8. 2002
    ..The purpose of this study was to evaluate the efficacy of anterior cervical plating for fusion enhancement after one- and two-level ACDF with cortical allograft...
  5. doi Lumbar total disc replacement from an extreme lateral approach: clinical experience with a minimum of 2 years' follow-up
    Luiz Pimenta
    Minimally Invasive and Reconstructive Spine Surgery, Instituto de Patologia da Coluna, Sao Paulo, Brazil
    J Neurosurg Spine 14:38-45. 2011
    ..In this study, the authors attempted to quantify the clinical and radiographic outcomes of a lateral approach to lumbar TDR from a prospective, single-center experience...
  6. ncbi Anterior cervical discectomy and fusion associated complications
    Kostas N Fountas
    Department of Neurosurgery, Medical Center of Central Georgia, Mercer University, School of Medicine, Macon, GA, USA
    Spine (Phila Pa 1976) 32:2310-7. 2007
    ..Retrospective review study with literature review...
  7. doi Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervi
    Daniel Murrey
    OrthoCarolina Spine Center, Charlotte, NC 28207, USA
    Spine J 9:275-86. 2009
    ..Cervical total disc replacement (TDR) is intended to address radicular pain and preserve functional motion between two vertebral bodies in patients with symptomatic cervical disc disease (SCDD)...
  8. ncbi Anterior approaches to fusion of the cervical spine: a metaanalysis of fusion rates
    Justin F Fraser
    Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
    J Neurosurg Spine 6:298-303. 2007
    ..The authors conducted a metaanalysis of studies published after 1990 in which fusion rates achieved with each procedure were reported for patients with degenerative disease at one, two, and three disc levels...
  9. ncbi Outcome after lumbar sequestrectomy compared with microdiscectomy: a prospective randomized study
    Claudius Thome
    Department of Neurosurgery, University Hospital Mannheim, Germany
    J Neurosurg Spine 2:271-8. 2005
    ..Therefore, the objective of this study was to compare early outcome and recurrence rates after sequestrectomy and microdiscectomy...
  10. ncbi Assessment of adjacent-segment disease in patients treated with cervical fusion or arthroplasty: a prospective 2-year study
    James T Robertson
    Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Neurosurg Spine 3:417-23. 2005
    ....
  11. ncbi Two-year outcome after lumbar microdiscectomy versus microscopic sequestrectomy: part 1: evaluation of clinical outcome
    Martin Barth
    Department of Neurosurgery, University Hospital Mannheim, Medical Faculty Mannheim of the Ruprecht Karls University of Heidelberg, Germany
    Spine (Phila Pa 1976) 33:265-72. 2008
    ..Single-center randomized prospective study at a university hospital...
  12. ncbi Disc height loss after anterior cervical microdiscectomy with titanium intervertebral cage fusion
    K Tureyen
    Suleyman Demirel University, Department of Neurosurgery, School of Medicine, Isparta, Turkey
    Acta Neurochir (Wien) 145:565-9; discussion 569-70. 2003
    ..This study was performed to determine the rate of narrowing of the cervical intervertebral disc after using a titanium cervical intervertebral cage (BAK-C; Sulzer Spine Tech, Minneapolis, MN)...
  13. doi Safety and effectiveness of bone allografts in anterior cervical discectomy and fusion surgery
    Larry E Miller
    Miller Scientific Consulting, Inc, Biltmore Lake, NC, USA
    Spine (Phila Pa 1976) 36:2045-50. 2011
    ..Systematic review...
  14. ncbi Surgical interventions for lumbar disc prolapse: updated Cochrane Review
    J N Alastair Gibson
    Spinal Unit, Royal Infirmary of Edinburgh and the University of Edinburgh, Edinburgh, Scotland
    Spine (Phila Pa 1976) 32:1735-47. 2007
    ..An updated Cochrane Review...
  15. doi A systematic review of randomized trials on the effect of cervical disc arthroplasty on reducing adjacent-level degeneration
    Ricardo Vieira Botelho
    Neurosurgical Service, Hospital do Servidor Público do Estado de São Paulo, Sao Paulo, Brazil
    Neurosurg Focus 28:E5. 2010
    ..Since 2002, cervical disc arthroplasty has been established as an alternative to fusion. The objective of this study was to review data concerning the role of cervical arthroplasty in reducing adjacent-level degeneration...
  16. ncbi An evidence-based review of the literature on the consequences of conservative versus aggressive discectomy for the treatment of primary disc herniation with radiculopathy
    William C Watters
    Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Spine J 9:240-57. 2009
    ..It remains unknown whether aggressive disc removal with curettage versus conservative removal of a disc fragment with little disc invasion provides a better outcome for the treatment of lumbar disc herniation with radiculopathy...
  17. doi Cages augmented with mineralized collagen and platelet-rich plasma as an osteoconductive/inductive combination for interbody fusion
    Matti Scholz
    Center for Spinal Surgery and Neurotraumatology, Traumaclinic Frankfurt Main, Germany
    Spine (Phila Pa 1976) 35:740-6. 2010
    ..After anterior cervical discectomy, fusion was radiologically, biomechanically, and histologically assessed in a sheep spine fusion model...
  18. ncbi One-level one-sided lumbar disc surgery with and without microscopic assistance: 1-year outcome in 114 consecutive patients
    Kudret Tureyen
    Department of Neurosurgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey
    J Neurosurg 99:247-50. 2003
    ..The aim of this study was to compare the outcomes following macrodiscectomy and microsurgery for one-level one-sided lumbar disc excision...
  19. ncbi Does anterior plating maintain cervical lordosis versus conventional fusion techniques? A retrospective analysis of patients receiving single-level fusions
    Stephan J Troyanovich
    Life Chiropractic College West, Hayward, California, USA
    J Spinal Disord Tech 15:69-74. 2002
    ..In comparison, the conventional method resulted in a net loss of overall lordosis and segmental lordosis at the surgical site...
  20. ncbi [Partial nucleotomy of the ovine disc as an in vivo model for disc degeneration]
    E Guder
    Hals Nasen Ohrenheilkunde, Universitätsklinikum Rostock
    Z Orthop Unfall 147:52-8. 2009
    ..The aim of this study was to develop a suitable animal model for the clinical situation of progressive disc degeneration after microsurgical nucleotomy...
  21. pmc Higher risk of dural tears and recurrent herniation with lumbar micro-endoscopic discectomy
    Marco Teli
    Department of Spinal Surgery, Galeazzi Orthopaedic Institute, Via Galeazzi 4, 20161 Milan, Italy
    Eur Spine J 19:443-50. 2010
    ..In conclusion, outcome measures are equivalent 2 years following lumbar discectomy with micro-endoscopy, microscopy or open technique, but severe complications are more likely and costs higher with micro-endoscopy...
  22. ncbi Endoscopic thoracic microdiscectomy
    Rod J Oskouian
    Department of Neurological Surgery, University of Virginia Health Systems, Charlottesville, Virginia, USA
    J Neurosurg Spine 3:459-64. 2005
    ..The purpose of this clinical study was to evaluate prospectively surgical and neurological outcomes after endoscopic thoracic disc surgery...
  23. ncbi A population-based study of reoperations after back surgery
    R W Hu
    Musculoskeletal Health Status Working Group, Division of Orthopaedics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Spine (Phila Pa 1976) 22:2265-70; discussion 2271. 1997
    ..More extensive surgery does not prevent nor predispose a patient to the need for further surgery...
  24. pmc Subsidence and nonunion after anterior cervical interbody fusion using a stand-alone polyetheretherketone (PEEK) cage
    Jae Jun Yang
    Depatment of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea
    Clin Orthop Surg 3:16-23. 2011
    ..The purposes of the present study are to evaluate the subsidence and nonunion that occurred after anterior cervical discectomy and fusion using a stand-alone intervertebral cage and to analyze the risk factors for the complications...
  25. doi Results of cervical arthroplasty compared with anterior discectomy and fusion: four-year clinical outcomes in a prospective, randomized controlled trial
    Rick C Sasso
    Indiana Spine Group, 8402 Harcourt Road, Suite 400, Indianapolis, IN 46260, USA
    J Bone Joint Surg Am 93:1684-92. 2011
    ..The purpose of this study was to evaluate the midterm safety and effectiveness of the Bryan disc as an alternative to arthrodesis following anterior cervical discectomy...
  26. ncbi Video-assisted thoracoscopic surgery for thoracic disc disease: Classification and outcome study of 100 consecutive cases with a 2-year minimum follow-up period
    Neel Anand
    Cedars Sinai Institute for Spinal Disorders, Cedars Sinai Medical Center, Los Angeles, California, USA
    Spine (Phila Pa 1976) 27:871-9. 2002
    ..Prospectively collected data from regular clinical follow-up evaluations were tabulated, analyzed, reviewed using a patient self-reported questionnaire...
  27. pmc Does minimally invasive lumbar disc surgery result in less muscle injury than conventional surgery? A randomized controlled trial
    Mark Arts
    Department of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands
    Eur Spine J 20:51-7. 2011
    ..Postoperative evaluation of CPK and the multifidus muscle showed similar results in both groups, although patients who underwent tubular discectomy reported more low-back pain during the first year after surgery...
  28. ncbi Removal of a protruded thoracic disc using microsurgical endoscopy. A new technique
    D Rosenthal
    Department of Neurosurgery, University Hospital, Frankfurt am Main Germany
    Spine (Phila Pa 1976) 19:1087-91. 1994
    ..It may shorten bed confinement and allow early return to active life. Application of this technique in other areas is being studied...
  29. pmc The NEtherlands Cervical Kinematics (NECK) trial. Cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in the treatment of cervical disc herniation; a double-blind randomised multicenter study
    Mark P Arts
    Department of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands
    BMC Musculoskelet Disord 11:122. 2010
    ..We present the design of the NECK trial, a randomised study on cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in patients with cervical disc herniation...
  30. ncbi Recurrent lumbar disk herniation
    Joseph K Lee
    Department of Orthopaedic Durgery, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, USA
    J Am Acad Orthop Surg 18:327-37. 2010
    Recurrent lumbar disk herniation is the most common complication following primary open diskectomy. It is defined as recurrent back and/or leg pain after a definite pain-free period lasting at least 6 months from initial surgery...
  31. ncbi Anterior corpectomy with iliac bone fusion or discectomy with interbody titanium cage fusion for multilevel cervical degenerated disc disease
    Shiuh Lin Hwang
    Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Spinal Disord Tech 20:565-70. 2007
    ..Clinical and radiologic study evaluating the outcome after anterior corpectomy with iliac bone fusion compared with discectomy with interbody titanium cage fusion for multilevel cervical degenerated disc disease...
  32. ncbi Three-level anterior cervical discectomy and fusion with plate fixation: radiographic and clinical results
    Elias C Papadopoulos
    Hospital for Special Surgery, New York, NY 10021, USA
    Spine (Phila Pa 1976) 31:897-902. 2006
    ..Retrospective review of patients with cervical spondylosis treated with 3-level anterior cervical discectomy and fusion with plate fixation...
  33. doi Outcomes of interbody fusion cages used in 1 and 2-levels anterior cervical discectomy and fusion: titanium cages versus polyetheretherketone (PEEK) cages
    Chi Chien Niu
    Department of Orthopedics Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan
    J Spinal Disord Tech 23:310-6. 2010
    ..A prospective study was performed in case with cervical spondylosis who underwent anterior cervical discectomy and fusion (ACDF) with titanium or polyetheretherketone (PEEK) cages...
  34. ncbi Incidence of dysphagia after anterior cervical spine surgery: a prospective study
    Rajesh Bazaz
    Spine Institute and Department of Orthopaedic Surgery, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Spine (Phila Pa 1976) 27:2453-8. 2002
    ..A prospective longitudinal study was conducted to evaluate dysphagia after anterior cervical spine surgery...
  35. pmc Comparison of postural control in unilateral stance between healthy controls and lumbar discectomy patients with and without pain
    Katie Bouche
    Rehabilitation Sciences and Physiotherapy, Ghent University Hospital, Ghent, Belgium
    Eur Spine J 15:423-32. 2006
    ..In addition, the influence of the extent of disc resection (unilateral/bilateral removal) and the side of operation on static balance control were investigated...
  36. ncbi Rehabilitation after lumbar disc surgery: an update Cochrane review
    Raymond W J G Ostelo
    EMGO Institute VU University Medical Centre, Amsterdam, The Netherlands
    Spine (Phila Pa 1976) 34:1839-48. 2009
    ..Cochrane systematic review of randomized controlled trials...
  37. ncbi The Cochrane review of surgery for lumbar disc prolapse and degenerative lumbar spondylosis
    J N Gibson
    University Department of Orthopaedic Surgery, Princess Margaret Rose Orthopaedic Hospital, Edinburgh, Scotland
    Spine (Phila Pa 1976) 24:1820-32. 1999
    ..A Cochrane review of randomized controlled trials...
  38. ncbi Subsidence after anterior cervical inter-body fusion. A randomized prospective clinical trial
    Erich Kast
    Department of Neurosurgery, Kantonsspital Winterthur, Brauerstrasse 15, CH 8401, Winterthur, Switzerland
    Neurosurg Rev 32:207-14; discussion 214. 2009
    ..Although there was no significant difference in a short-term clinical result between the two treatment groups, we recommend the use of cages which preserve the determined segmental height and lordosis...
  39. ncbi Prospective multiple outcomes study of outpatient lumbar microdiscectomy: should 75 to 80% success rates be the norm?
    Harold L Asch
    Buffalo Neurosurgery Group, New York 14224, USA
    J Neurosurg 96:34-44. 2002
    ..The authors use the methodology and data derived from their study to evaluate critically the relevance of these two categories of success rates...
  40. ncbi Subsidence of the wing titanium cage after anterior cervical interbody fusion: 2-year follow-up study
    Kirsten Schmieder
    Department of Neurosurgery, Ruhr University Bochum, Germany
    J Neurosurg Spine 4:447-53. 2006
    ..The aim of this prospective study was to evaluate subsidence and total segmental height after implantation of a newly designed Wing titanium cage. Furthermore, alignment of the entire cervical spine was analyzed 2 years after surgery...
  41. pmc Clinical experience in cell-based therapeutics: intervention and outcome
    Hans Joerg Meisel
    Bergmannstrost, Neurochirurgie klinik, Merseburger Strasse 165, 06112, Halle, Saale, Germany
    Eur Spine J 15:S397-405. 2006
    ....
  42. ncbi Comparison of surgical outcomes between macro discectomy and micro discectomy for lumbar disc herniation: a prospective randomized study with surgery performed by the same spine surgeon
    Yoshito Katayama
    Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, 466 8550, Japan
    J Spinal Disord Tech 19:344-7. 2006
    ..A prospective study was conducted on the surgical procedures for lumbar disc herniation...
  43. ncbi Posterior foraminotomy or anterior discectomy with polymethyl methacrylate interbody stabilization for cervical soft disc disease: results in 292 patients with monoradiculopathy
    Marcus C Korinth
    Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany
    Spine (Phila Pa 1976) 31:1207-14; discussion 1215-6. 2006
    ..Retrospective study of patients who underwent either ventral microdiscectomy and polymethyl methacrylate (PMMA) interbody stabilization or posterior foraminotomy for the treatment of cervical monoradiculopathy caused by soft disc disease...
  44. ncbi Less systemic cytokine response in patients following microendoscopic versus open lumbar discectomy
    Tsung Jen Huang
    Department of Orthopedic Surgery, Chang Gung Memorial Hospital at Chia Yi, College of Medicine, Chang Gung University, Putz City, Chia Yi, Taiwan
    J Orthop Res 23:406-11. 2005
    ..Moreover, our MED patients had achieved satisfactory clinical outcomes as the OD patients at a mean 18.9 months follow-up after surgery...
  45. ncbi A 10-year follow-up of the outcome of lumbar microdiscectomy
    G F Findlay
    Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    Spine (Phila Pa 1976) 23:1168-71. 1998
    ..Patient satisfaction with the results of microdiscectomy 10 years later was high. CONCLUSIONS: Lumbar microdiscectomy achieves a high level of initial success, and this positive outcome is maintained at a 10-year follow-up...
  46. ncbi Polyetheretherketone as a biomaterial for spinal applications
    Jeffrey M Toth
    Department of Orthopaedic Surgery, Medical College of Wisconsin, 9200 W Wisconsin Ave, Box 26099, Milwaukee, WI 53226 0099, USA
    Biomaterials 27:324-34. 2006
    ..Based on these results, the polymeric biomaterial PEEK may be a useful biomaterial for interbody fusion cages due to the polymer's increased radiolucency and decreased stiffness...
  47. ncbi Increased fusion rates with cervical plating for three-level anterior cervical discectomy and fusion
    J C Wang
    UCLA Department of Orthopaedic Surgery, UCLA School of Medicine, Los Angeles, California 90095 6902, USA
    Spine (Phila Pa 1976) 26:643-6; discussion 646-7. 2001
    ..A retrospective review of all patients surgically treated by a single surgeon with a three-level anterior cervical discectomy and fusion with and without anterior plate fixation...
  48. ncbi Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft
    Douglas B Moreland
    Buffalo Neurosurgery Group, 550 Orchard Park Road, Buffalo, NY 14224, USA
    Spine J 4:184-91; discussion 191. 2004
    ..One of these devices is the titanium Rabea cage (Signus, Alzenau, Germany) [correction]. There are no peer-reviewed objective reports on the use of these cages in cervical discectomy...
  49. ncbi Is autograft the gold standard in achieving radiographic fusion in one-level anterior cervical discectomy and fusion with rigid anterior plate fixation?
    Dino Samartzis
    Department of Orthopaedic Surgery, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Spine (Phila Pa 1976) 30:1756-61. 2005
    ..A review of 66 consecutive patients at a single institution who underwent one-level anterior cervical discectomy and fusion (ACDF) with rigid anterior plate fixation with allograft or autograft...
  50. ncbi Efficacy of anterior cervical fusion: comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts
    Yu Cheng Chou
    Division of Functional Neuroscience, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    J Clin Neurosci 15:1240-5. 2008
    ..3% in group B, and 84.85% in group C. The fusion rates after 1 year in groups A, B, and C were 46.51%, 100% and 100%, respectively. The PEEK cage is a viable alternative to autogenous tricortical bone grafts in anterior cervical fusion...
  51. doi Mesh cage reconstruction with autologous cancellous graft in anterior cervical discectomy and fusion
    Christopher K Kepler
    Spine and Scoliosis Service, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
    J Spinal Disord Tech 23:328-32. 2010
    ..Retrospective case series...
  52. ncbi Radiographic and clinical outcomes following single-level anterior cervical discectomy and allograft fusion without plate placement or cervical collar
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Box 800212, Charlottesville, Virginia 22908, USA
    J Neurosurg Spine 8:420-8. 2008
    ..This paper examines a single-surgeon experience with single-level ACDF without use of plates or hard collars in patients with degenerative spondylosis in whom allograft was used as the fusion material...
  53. ncbi Risk of multiple reoperations after lumbar discectomy: a population-based study
    Heikki Osterman
    ORTON Orthopaedic Hospital, Invalid Foundation, Helsinki, Finland
    Spine (Phila Pa 1976) 28:621-7. 2003
    ..Retrospective follow-up study of patients undergoing multiple (two or more) reoperations after initial lumbar discectomy using an administrative database...
  54. ncbi A comparison of changes over time in cervical foraminal height after tricortical iliac graft or polyetheretherketone cage placement following anterior discectomy
    Suat E Celik
    Department of Neurosurgery, Beyoglu State Hospital, Istanbul, Turkey
    J Neurosurg Spine 6:10-6. 2007
    ..To their knowledge, this prospective study is the first in which foraminal height changes over time are compared following the placement of a tricortical graft or a polyetheretherketone (PEEK) cage...
  55. ncbi Vascular injury complicating lumbar disc surgery. A systematic review
    S Papadoulas
    Department of Surgery, Vascular Surgery Unit, University Hospital of Patras, Patras, Greece
    Eur J Vasc Endovasc Surg 24:189-95. 2002
    ..to review the literature concerning the early and late vascular complications of lumbar disc surgery...
  56. ncbi Discectomy versus discectomy with fusion versus discectomy with fusion and instrumentation: a prospective randomized study
    Jing Cheng Xie
    University of Calgary Spine Program, Foothills Hospital and Medical Centre, Calgary, Canada
    Neurosurgery 61:107-16; discussion 116-7. 2007
    ....
  57. ncbi Long-term results after anterior cervical discectomy and fusion with allograft and plating: a 5- to 11-year radiologic and clinical follow-up study
    Wai Mun Yue
    Study performed at the Columbia Spine Centre, Columbia, MO, USA
    Spine (Phila Pa 1976) 30:2138-44. 2005
    ..A retrospective review...
  58. ncbi Multilevel cervical fusion without plates, screws or autogenous iliac crest bone graft
    Mehmet Nusret Demircan
    GATA Haydarpasa Training Hospital, Department of Neurosurgery, Istanbul, Turkey
    J Clin Neurosci 14:723-8. 2007
    ....
  59. pmc Cervical disc herniation and cervical spondylosis surgically treated by Cloward procedure: a 10-year-minimum follow-up study
    Cesare Faldini
    Department of Orthopaedic Surgery, Istituto Ortopedico Rizzoli, University of Bologna, Via G Pupilli 1, 40136, Bologna, Italy
    J Orthop Traumatol 11:99-103. 2010
    ....
  60. ncbi Effects of a cervical disc prosthesis on segmental and cervical spine alignment
    Gwynedd E Pickett
    Division of Neurosurgery, Department of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada
    Neurosurg Focus 17:E5. 2004
    ..The impact of cervical arthroplasty on sagittal alignment of the FSU needs to be addressed, together with its effect on overall sagittal balance of the cervical spine...
  61. ncbi Standard open microdiscectomy versus minimal access trocar microdiscectomy: results of a prospective randomized study
    Yu Mi Ryang
    Department of Neurosurgery, University Hospital Rheinisch Westfäl Technische Hochschule Aachen, Aachen University, Aachen, Germany
    Neurosurgery 62:174-81; discussion 181-2. 2008
    ..5 mm trocar system for minimal access to the spine...
  62. pmc Five-year outcome of stand-alone fusion using carbon cages in cervical disc arthrosis
    N Marotta
    Department of Neurosurgery, University of Rome Sapienza, Rome, Italy
    Eur Spine J 20:S8-12. 2011
    ..In the opinion, pseudoarthrosis is caused by malpositioning of the carbon fiber cage...
  63. ncbi Treatment of multilevel cervical fusion with cages
    Der Yang Cho
    Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan, Republic of China
    Surg Neurol 62:378-85, discussion 385-6. 2004
    ..In this study, we try to use cages to replace plate function in multilevel cervical fusion...
  64. ncbi Recurrent lumbar disc herniation after discectomy: outcome of repeat discectomy
    Li Yang Dai
    Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Second Medical University, Shanghai 200092, China
    Surg Neurol 64:226-31; discussion 231. 2005
    ..The purpose of the current study was to address the outcome in the patients who had recurrent disc herniation treated with repeat discectomy and to identify the factors that may influence the outcome...
  65. ncbi Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion
    Jeff S Silber
    Department of Orthopaedic Surgery, Long Island Jewish Medical Center, New Hyde Park, New York, USA
    Spine (Phila Pa 1976) 28:134-9. 2003
    ..j.a.)...
  66. ncbi Pseudoarthrosis of the cervical spine: a comparison of radiographic diagnostic measures
    Lisa K Cannada
    Department of Orthopaedics, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Spine (Phila Pa 1976) 28:46-51. 2003
    ..A retrospective review was conducted...
  67. pmc Microendoscopic lumbar discectomy versus open surgery: an intraoperative EMG study
    U Schick
    Neurological Surgery Clinic, University of Leipzig, Germany
    Eur Spine J 11:20-6. 2002
    ..The study showed that microendoscopic discectomy allows a smaller incision and less tissue trauma with comparable visualization of the nerve structures than does open surgery...
  68. pmc Reoperations after first lumbar disc herniation surgery; a special interest on residives during a 5-year follow-up
    Arja Hakkinen
    Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, Jyvaskyla, Finland
    BMC Musculoskelet Disord 8:2. 2007
    ....
  69. pmc Comparison of a minimally invasive procedure versus standard microscopic discotomy: a prospective randomised controlled clinical trial
    Jörg Franke
    Department of Orthopaedic Surgery, Otto von Guericke University of Magdeburg, Magdeburg, Germany
    Eur Spine J 18:992-1000. 2009
    ....
  70. ncbi Iliac artery injury during lumbar microdiscectomy
    Zbigniew Karwacki
    Department of Neuroanaesthesiology, Medical University of Gdansk
    Anestezjol Intens Ter 42:24-6. 2010
    ..Accidental laceration of major abdominal vessels during lumbar disc surgery is a relatively rare complication that requires rapid diagnosis and management...
  71. ncbi Clinical and radiological results following cervical arthroplasty
    D H Yoon
    Department of Neurosurgery, Yonsei University, College of Medicine, Seoul, Korea
    Acta Neurochir (Wien) 148:943-50. 2006
    ..This was a retrospective study of clinical and radiological results of cervical arthroplasty using the Bryan cervical disc prosthesis to evaluate the efficacy of arthroplasty in clinical applications...
  72. ncbi Early active training after lumbar discectomy. A prospective, randomized, and controlled study
    G Kjellby Wendt
    Department of Orthopaedics, Sahlgrenska University Hospital, Ostra, Gothenburg, Sweden
    Spine (Phila Pa 1976) 23:2345-51. 1998
    ..At 2 years' follow-up, more patients were satisfied with the result of the operation. The early active treatment program is recommended...
  73. ncbi Discectomy strategies for lumbar disc herniation: results of the LAPDOG trial
    Stephen J Haines
    Department of Neurological Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Clin Neurosci 9:411-7. 2002
    ..Such evidence should be required by patients to whom such procedures are proposed and those who are asked to pay for them...
  74. doi Sagittal alignment after Bryan cervical arthroplasty
    Rick C Sasso
    Indiana Spine Group, Indiana University School of Medicine, Indianapolis 46260, USA
    Spine (Phila Pa 1976) 36:991-6. 2011
    ..Prospective, randomized, Food and Drug Administration Investigational Device Exemption trial from one study site...
  75. doi Systematic review and meta-analysis of randomized controlled trials: comparison of total disk replacement with anterior cervical decompression and fusion
    Lin Yu
    Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People s Republic of China
    Orthopedics 34:e651-8. 2011
    ..evaluate whether there is a beneficial clinical effect of total disk replacement compared with anterior cervical diskectomy and fusion for the treatment of single-level symptomatic cervical disk disease...
  76. doi Non-fusion rates in anterior cervical discectomy and implantation of empty polyetheretherketone cages
    Ioannis Pechlivanis
    Department of Neurosurgery, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany
    Spine (Phila Pa 1976) 36:15-20. 2011
    ..A prospective analysis...
  77. doi Radiographic PEEK double-lucency finding after anterior cervical discectomy and fusion with local autograft and PEEK spacer: a preliminary study
    Leslie C Hellbusch
    Department of Surgery Neurosurgery, Nebraska Medical Center, Omaha, Nebraska, USA
    J Neurosurg Spine 16:248-50. 2012
    ..The authors conclude that the radiolucent feature of the PEEK cage, which produces the image finding PEEK double lucency, aids in the determination of fusion...
  78. ncbi Delayed diagnosis of vascular injuries during lumbar discectomy
    J L Hanouz
    Department of Anesthesiology and Surgical Intensive Care, CHRU of Caen, France
    J Clin Anesth 12:64-6. 2000
    ..An emergent laparotomy was performed to repair vascular injuries. The delayed symptoms, use of medical antishock trousers, and implications for anesthetists are discussed...
  79. ncbi Use of a polymethylmethacrylate cervical cage in the treatment of single-level cervical disc disease
    Jyi Feng Chen
    Department of Neurosurgery, Chang Gung University and Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Neurosurg Spine 3:24-8. 2005
    ..To achieve cervical interbody fusion, the authors designed a modified PMMA cervical cage that they filled with spongy bone for the treatment of single-level cervical disc herniation...
  80. ncbi Minimally invasive far lateral microendoscopic discectomy for extraforaminal disc herniation at the lumbosacral junction: cadaveric dissection and technical case report
    John E O'Toole
    Department of Neurosurgery, Rush University Medical Center, 1725 W Harrison Street, Chicago, IL 60612, USA
    Spine J 7:414-21. 2007
    ..Reports specifically describing minimally invasive surgical approaches to lumbosacral ELDHs are lacking...
  81. ncbi Titanium or polymethylmethacrylate in cervical disc surgery? A prospective study
    B Jöllenbeck
    Klinik für Neurochirurgie, Otto von Guericke Universitat Magdeburg, Germany
    Zentralbl Neurochir 62:200-2. 2001
    ..Results were similar in terms of complications and clinical outcome. As the PMMA surgery took longer and the costs of titanium are higher, there is no marked advantage of one implant material over the other...
  82. pmc Prevertebral soft tissue swelling after anterior cervical discectomy and fusion with plate fixation
    K S Suk
    Department of Orthopaedic Surgery, College of Medicine, Kyung Hee University, 1 Heogi dong, Dongdamun Ku, Seoul, South Korea
    Int Orthop 30:290-4. 2006
    ..1%). In conclusion, in this prospective study of 87 patients fused at one or two levels in the cervical spine peak prevertebral soft tissue swelling was observed on the second and third days after the surgery...
  83. ncbi Prognostic role of depression after lumbar disc surgery
    L Arpino
    Department of Neurosurgery, Second University of Naples, Naples, Italy
    Neurol Sci 25:145-7. 2004
    ..In agreement with the literature, our results confirm the negative role of depression in outcome after lumbar disc surgery. We emphasize the consideration of psychological factors in the management of lumbar disc herniation...
  84. ncbi [Polymethylmethacrylate (PMMA) in anterior cervical spine surgery - current situation in Germany]
    J Schroder
    Klinik und Poliklinik fur Neurochirurgie, Universitatsklinikum, Westfalische Wilhelms Universitat Munster
    Zentralbl Neurochir 62:33-6. 2001
    ..33% per year). - In conclusion PMMA is still the most widely used spacer material after anterior cervical discectomy in Germany. An increased complication rate in comparison with other implants could not be observed...
  85. ncbi Posterolateral endoscopic excision for lumbar disc herniation: Surgical technique, outcome, and complications in 307 consecutive cases
    Anthony Tung Yeung
    Arizona Orthopedic Surgeons, Phoenix, Arizona, USA
    Spine (Phila Pa 1976) 27:722-31. 2002
    ..A retrospective review involving 307 consecutive cases of lumbar disc herniation managed by posterolateral endoscopic discectomy was conducted...
  86. ncbi Surgical treatment of dysphagia after anterior cervical interbody fusion
    Guy R Fogel
    Houston Spine Surgery, 5225 Katy Freeway, Suite 600, Houston, TX 77007, USA
    Spine J 5:140-4. 2005
    ..A surgical treatment of dysphagia after ACIF has not been reported...
  87. ncbi Airway changes after anterior cervical discectomy and fusion
    Shane A Andrew
    Mount Clemens General Hospital, Michigan State University Statewide Campus System, Mount Clemens, MI, USA
    J Spinal Disord Tech 20:577-81. 2007
    ..To date no published data exist in the English literature upon which to judge symptomatic patients (experiencing postoperative airway distress) radiographically...
  88. pmc A systematic review of randomised clinical trials using posterior discectomy to treat lumbar disc herniations
    Alberto Gotfryd
    Orthopaedics and Traumatology, Santa Casa School of Medicine and Hospitals of São Paulo, Sao Paulo, Brazil
    Int Orthop 33:11-7. 2009
    ..No conclusions could be drawn from the clinical randomised studies reviewed regarding the safety of the three techniques studied due to insufficient data on postoperative complications...
  89. ncbi Micro-endoscopic-discectomy (MED) for far lateral disc herniation in the lumbar spine. Technical note
    P Cervellini
    Department of Neurosurgery, Vicenza Hospital, Vicenza, Italy
    Acta Neurochir Suppl 92:99-101. 2005
    ..Extraforaminal disc herniation can be diagnosed with the aid of CT scan and MRI. The minimally invasive surgical treatment via the micro-endoscopic far lateral approach, in our initial experience, has a high rate of succes...
  90. pmc Effects of a cervical disc prosthesis on maintaining sagittal alignment of the functional spinal unit and overall sagittal balance of the cervical spine
    Seok Woo Kim
    International Spine Center, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, South Korea
    Eur Spine J 17:20-9. 2008
    ..The Bryan disc preserves motion of the FSU. Although the preoperative lordosis (or kyphosis) of the FSU could not always be maintained during the follow-up period, the overall sagittal balance of the cervical spine was usually preserved...
  91. pmc Biomechanical study of a hat type cervical intervertebral fusion cage
    Yu Tong Gu
    Department of Orthopaedics, Zhongshan Hospital of Fudan corrected University, Shanghai, 200032 corrected People s Republic of China
    Int Orthop 31:101-5. 2007
    ..Volume-related stiffness of all cages was higher than that of iliac bone graft. The Harms cage was highest in volume-related stiffness in all directions. The HCIFC can provide enough primary stability for cervical intervertebral fusion...
  92. doi The incidence of adjacent segment disease requiring surgery after anterior cervical diskectomy and fusion: estimation using an 11-year comprehensive nationwide database in Taiwan
    Jau Ching Wu
    Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
    Neurosurgery 70:594-601. 2012
    The incidence of symptomatic adjacent segment disease (ASD) after anterior cervical diskectomy and fusion (ACDF) was reported as 2.9%/y in a previous cohort of 374 patients...
  93. ncbi Efficacy of dynamic lumbar stabilization exercise in lumbar microdiscectomy
    Figen Yilmaz
    Department of Physical Medicine and Rehabilitation, Sisli Etfal Education and Research Hospital, Istanbul, Turkey
    J Rehabil Med 35:163-7. 2003
    ..The aim of this study was to determine the efficacy of dynamic lumbar stabilization exercises in patients with lumbar microdiscectomy...
  94. ncbi Dysphonia and dysphagia following the anterior approach to the cervical spine
    C P Winslow
    Department of Otolaryngology Head and Neck Surgery, Oregon Health Sciences University, Portland, USA
    Arch Otolaryngol Head Neck Surg 127:51-5. 2001
    ..Despite functional morbidity and legal implications, the incidence and etiologic factors of these complications have not been adequately elucidated...
  95. ncbi Technique of microendoscopy in medial lumbar disc herniation
    U Schick
    Clinic of Neurological Surgery, University of Leipzig, Leipzig, Germany
    Minim Invasive Neurosurg 45:139-41. 2002
    ..The technique allows a smaller incision and less tissue trauma with comparable visualization of the nerve structures than does standard open surgery...
  96. ncbi PMMA versus titanium cage after anterior cervical discectomy - a prospective randomized trial
    J Schroder
    Department of Neurosurgery, University Clinics Muenster, Germany
    Zentralbl Neurochir 68:2-7. 2007
    ....
  97. doi Obesity increases the risk of recurrent herniated nucleus pulposus after lumbar microdiscectomy
    Dennis S Meredith
    Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY 10021, USA
    Spine J 10:575-80. 2010
    ..Recurrent herniation of the nucleus pulposus (HNP) frequently causes poor outcomes after lumbar discectomy. The relationship between obesity and recurrent HNP has not previously been reported...
  98. ncbi Biomechanical comparison of cervical spine interbody fusion cages
    F Kandziora
    Unfall und Wiederherstellungschirurgie, and the Strahlenklinik und Poliklinik Universitätsklinikum Charité der Humboldt Universität Berlin, Campus Virchow Klinikum, Berlin, Germany
    Spine (Phila Pa 1976) 26:1850-7. 2001
    ..An in vitro biomechanical study of cervical spine interbody fusion cages using a sheep model was conducted...
  99. pmc Polyetheretherketone (PEEK) cage filled with cancellous allograft in anterior cervical discectomy and fusion
    Jen Chung Liao
    Orthopedics, Chang Gung University, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Int Orthop 32:643-8. 2008
    ..Analysis of the results indicated the cancellous allograft bone-filled PEEK cage used in ACDF is a good choice for patients with cervical disc disease, and avoids the complications of harvesting iliac autograft...
  100. ncbi Use of the Solis cage and local autologous bone graft for anterior cervical discectomy and fusion: early technical experience
    Amjad Shad
    Department of Neurological Surgery, Radcliffe Infirmary, Oxford, United Kingdom
    J Neurosurg Spine 2:116-22. 2005
    ....
  101. doi The impact of minimally invasive spine surgery on perioperative complications in overweight or obese patients
    Paul Park
    Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan 48109 5338, USA
    Neurosurgery 62:693-9; discussion 693-9. 2008
    ..The impact of minimally invasive spinal (MIS) surgery on the incidence of perioperative adverse events in overweight or obese patients, however, has not been well evaluated...

Research Grants89

  1. RECOVERY OF INTERVERTEBRAL DISC AFTER ENZYME TREATMENT
    Theodore Oegema; Fiscal Year: 1991
    ..allows regrowth of disc, B) multiple protease injected discs which produces fibrotic replacement, C) modest diskectomy with no disruption of the endplates and only a small hole through the anulus which allows anulus regrowth, D) ..
  2. PERCUTANEOUS LASER DISCECTOMY
    MICHAEL LESIECKI; Fiscal Year: 1991
    ..Phase I results show that the laser approach was statistically equivalent to accepted automated percutaneous diskectomy methods in-vitro as measured by disk elastance (pressure/volume response)...
  3. Tests of Models of Retinal/Optic Nerve Diseases&Adaption
    Donald Hood; Fiscal Year: 2004
    ..Finally, patients with acute optic neuritis will be followed with behavioral and mVEP techniques. An attempt will be made to understand the recovery o vision following optic neuritis (ON). ..
  4. MEASURE OF RECEPTOR AND POST RECEPTOR ACTIVITY
    Donald Hood; Fiscal Year: 2000
    ..monkeys in which INL activity is pharmacologically dissected, b. normal human subjects, c. patients with disease of the INL, and d. mathematical work. ..
  5. Tests of Models of Retinal/Optic Nerve Diseases&Adaption
    Donald Hood; Fiscal Year: 2001
    ..Finally, patients with acute optic neuritis will be followed with behavioral and mVEP techniques. An attempt will be made to understand the recovery o vision following optic neuritis (ON). ..
  6. MEASURE OF RECEPTOR AND POST RECEPTOR ACTIVITY
    Donald Hood; Fiscal Year: 2001
    ..monkeys in which INL activity is pharmacologically dissected, b. normal human subjects, c. patients with disease of the INL, and d. mathematical work. ..
  7. TESTS OF MODELS OF RETINAL DISEASE ADAPTATION
    Donald Hood; Fiscal Year: 2000
    ..This could be especially valuable in assessing retinal function of patients with heterogeneous damage as in retinitis pigmentosa, diabetic retinopathy, and glaucoma. ..
  8. MEASURE OF RECEPTOR AND POST RECEPTOR ACTIVITY
    Donald Hood; Fiscal Year: 2002
    ..monkeys in which INL activity is pharmacologically dissected, b. normal human subjects, c. patients with disease of the INL, and d. mathematical work. ..
  9. Tests of Models of Retinal/Optic Nerve Diseases&Adaption
    Donald Hood; Fiscal Year: 2002
    ..Finally, patients with acute optic neuritis will be followed with behavioral and mVEP techniques. An attempt will be made to understand the recovery o vision following optic neuritis (ON). ..
  10. Measures of Human Receptor and Post Receptor Activity
    Donald Hood; Fiscal Year: 2009
    ..These same techniques can enable the ophthalmologist to monitor the health of these cells and, thus the effectiveness of alternative treatments. ..
  11. Studying models and mechanisms of optic nerve diseases
    Donald Hood; Fiscal Year: 2009
    ..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..
  12. Measures of Human Receptor and Post Receptor Activity
    Donald Hood; Fiscal Year: 2008
    ..We propose as part of aim 3 to improve our understanding of these relationships as well as to improve our analysis of visual field data. [unreadable] [unreadable]..
  13. Studying models and mechanisms of optic nerve diseases
    Donald Hood; Fiscal Year: 2007
    ..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..
  14. Measures of Human Receptor and Post Receptor Activity
    Donald Hood; Fiscal Year: 2007
    ..We propose as part of aim 3 to improve our understanding of these relationships as well as to improve our analysis of visual field data. [unreadable] [unreadable]..
  15. Studying models and mechanisms of optic nerve diseases
    Donald Hood; Fiscal Year: 2006
    ..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..
  16. Measures of Human Receptor and Post Receptor Activity
    Donald Hood; Fiscal Year: 2006
    ..We propose as part of aim 3 to improve our understanding of these relationships as well as to improve our analysis of visual field data. [unreadable] [unreadable]..
  17. Studying models and mechanisms of optic nerve diseases
    Donald Hood; Fiscal Year: 2005
    ..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..
  18. Measures of Human Receptor and Post Receptor Activity
    Donald Hood; Fiscal Year: 2005
    ..We propose as part of aim 3 to improve our understanding of these relationships as well as to improve our analysis of visual field data. ..
  19. Measures of Human Receptor and Post Receptor Activity
    Donald Hood; Fiscal Year: 2004
    ..We propose as part of aim 3 to improve our understanding of these relationships as well as to improve our analysis of visual field data. ..
  20. Tests of Models of Retinal/Optic Nerve Diseases&Adaption
    Donald Hood; Fiscal Year: 2003
    ..Finally, patients with acute optic neuritis will be followed with behavioral and mVEP techniques. An attempt will be made to understand the recovery o vision following optic neuritis (ON). ..
  21. Measures of Human Receptor and Post Receptor Activity
    Donald C Hood; Fiscal Year: 2010
    ..These same techniques can enable the ophthalmologist to monitor the health of these cells and, thus the effectiveness of alternative treatments. ..
  22. MEASURE OF HUMAN RECEPTOR AND POST-RECEPTOR ACTIVITY
    Donald Hood; Fiscal Year: 1993
    ..Thus, we propose to develop a model of the human ERG that encompasses the activity of the inner nuclear layer as well as the receptors...
  23. MEASURE OF RECEPTOR AND POST RECEPTOR ACTIVITY
    Donald Hood; Fiscal Year: 1999
    ..monkeys in which INL activity is pharmacologically dissected, b. normal human subjects, c. patients with disease of the INL, and d. mathematical work. ..
  24. TESTS OF MODELS OF RETINAL DISEASE ADAPTATION
    Donald Hood; Fiscal Year: 1999
    ..This could be especially valuable in assessing retinal function of patients with heterogeneous damage as in retinitis pigmentosa, diabetic retinopathy, and glaucoma. ..
  25. TESTS OF MODELS OF RETINAL DISEASE AND ADAPTATION
    Donald Hood; Fiscal Year: 1991
    ..Finally, we intend to obtain a better understanding of the relative involvement of the rod and different cone mechanisms in retinitis pigmentosa and in progressive cone dystrophy...
  26. TESTS OF MODELS OF RETINAL DISEASE AND ADAPTATION
    Donald Hood; Fiscal Year: 1990
    ..Finally, we intend to obtain a better understanding of the relative involvement of the rod and different cone mechanisms in retinitis pigmentosa and in progressive cone dystrophy...
  27. TESTS OF MODELS OF RETINAL DISEASE AND ADAPTATION
    Donald Hood; Fiscal Year: 1993
    ..The data will be analyzed within the context of recent models of cone systems, models based on recent physiology...
  28. TESTS OF MODELS OF RETINAL DISEASE AND ADAPTATION
    Donald Hood; Fiscal Year: 1992
    ..The data will be analyzed within the context of recent models of cone systems, models based on recent physiology...
  29. MEASURE OF HUMAN RECEPTOR AND POST-RECEPTOR ACTIVITY
    Donald Hood; Fiscal Year: 1992
    ..Thus, we propose to develop a model of the human ERG that encompasses the activity of the inner nuclear layer as well as the receptors...
  30. Low Back: A Multi-Center Clinical Trial
    James Weinstein; Fiscal Year: 2007
    ..abstract_text> ..
  31. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2005
    ....
  32. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2006
    ....
  33. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2007
    ....
  34. MECHANISMS & PERFORMANCE OF TRACEABLE UHMWPE IMPLANTS
    Steven Kurtz; Fiscal Year: 2001
    ..The purpose of this proposed research is to examine the influence of mechanical degradation after implantation on the clinical performance of metal-backed acetabular components for total hip arthroplasty. ..
  35. Orthopaedic Resident Clinician/Researcher Program
    James Weinstein; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  36. Wear, Inflammation and Clinical Performance of Total Disc Replacement
    STEVEN MICHAEL KURTZ; Fiscal Year: 2010
    ..Thus, successful achievement of the proposed research will provide essential information on TDR implant performance and on clinical outcomes, which are needed for informed health care decisions. ..
  37. MECHANISMS & PERFORMANCE OF TRACEABLE UHMWPE IMPLANTS
    Steven Kurtz; Fiscal Year: 2002
    ..The purpose of this proposed research is to examine the influence of mechanical degradation after implantation on the clinical performance of metal-backed acetabular components for total hip arthroplasty. ..
  38. Orthopaedic Resident Clinician/Researcher Program
    James Weinstein; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  39. MECHANISMS & PERFORMANCE OF TRACEABLE UHMWPE IMPLANTS
    Steven Kurtz; Fiscal Year: 2003
    ..The purpose of this proposed research is to examine the influence of mechanical degradation after implantation on the clinical performance of metal-backed acetabular components for total hip arthroplasty. ..
  40. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2009
    ....
  41. Low Back: A Multi-Center Clinical Trial
    James Weinstein; Fiscal Year: 2008
    ..abstract_text> ..
  42. Mechanics and Performance of Traceable UHMWPE Implants
    Steven Kurtz; Fiscal Year: 2008
    ....
  43. IMMEDIATE VS DELAYED RECONSTRUCTION AND BREAST CANCER SURGERY COMPLICATIONS
    Margaret A Olsen; Fiscal Year: 2010
    ..This study will provide important new information to determine the optimal timing and type of reconstructive surgery for women after mastectomy based on their underlying illnesses. ..
  44. Mechanism of Cognitive Dysfunction: CEA and Stenting
    ERIC JOHN HEYER; Fiscal Year: 2010
    ....
  45. Individual Differences in Pain Modulation as Predictors of Post-Surgical Pain
    Robert Edwards; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  46. Tissue Engineering Utilizing BMP Gene Therapy
    GREGORY HELM; Fiscal Year: 2004
    ....
  47. Neuropsychological Outcome of Carotid Endarterectomy
    ERIC HEYER; Fiscal Year: 2001
    ..EEG is inadequate to determine this subtle degree of hypoperfusion. ..
  48. Functional Health CAT in Diabetes
    Carolyn Schwartz; Fiscal Year: 2004
    ..abstract_text> ..
  49. Development of a Spinal Intervertebral Disc Prosthesis
    GLENN BUTTERMANN; Fiscal Year: 2003
    ..The objective of Phase I is to demonstrate that the device restores normal spine biomechanics (range of motion and stiffness) and is durable in fatigue testing. ..
  50. Neuropsychological Outcome of Carotid Endarterectomy
    ERIC HEYER; Fiscal Year: 2004
    ..EEG is inadequate to determine this subtle degree of hypoperfusion. ..
  51. Neuropsychological Outcome of Carotid Endarterectomy
    ERIC HEYER; Fiscal Year: 2002
    ..EEG is inadequate to determine this subtle degree of hypoperfusion. ..
  52. IN SITU LIGATION FOR DETECTION OF SPECIFIC DNA DAMAGE
    David Baskin; Fiscal Year: 1999
    ..It, therefore, can be used in molecular and cell biology research, as well as by clinicians in many fields, including pathology oncology, cardiology and the clinical neurosciences. ..
  53. Catastrophizing and Pain in Rheumatoid Arthritis
    Robert Edwards; Fiscal Year: 2007
    ..abstract_text> ..
  54. IN SITU LIGATION FOR DETECTION OF SPECIFIC DNA DAMAGE
    David Baskin; Fiscal Year: 2000
    ..It, therefore, can be used in molecular and cell biology research, as well as by clinicians in many fields, including pathology oncology, cardiology and the clinical neurosciences. ..
  55. IN SITU LIGATION FOR DETECTION OF SPECIFIC DNA DAMAGE
    David Baskin; Fiscal Year: 2001
    ..It, therefore, can be used in molecular and cell biology research, as well as by clinicians in many fields, including pathology oncology, cardiology and the clinical neurosciences. ..
  56. Tissue Engineering Utilizing BMP Gene Therapy
    GREGORY HELM; Fiscal Year: 2002
    ....
  57. Mechanism of Cognitive Dysfunction: CEA and Stenting
    ERIC HEYER; Fiscal Year: 2009
    ....
  58. IN SITU LIGATION FOR DETECTION OF SPECIFIC DNA DAMAGE
    David Baskin; Fiscal Year: 1999
    ..It, therefore, can be used in molecular and cell biology research, as well as by clinicians in many fields, including pathology oncology, cardiology and the clinical neurosciences. ..
  59. Incidence & Outcomes of SSI After Breast Cancer Surgery
    Margaret Olsen; Fiscal Year: 2008
    ....
  60. Individual Differences in Pain Modulation as Predictors of Post-Surgical Pain
    Robert Edwards; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  61. Surgical Site and Clostridium difficile Infections after Ambulatory Surgery
    Margaret A Olsen; Fiscal Year: 2010
    ..This study will provide important new information that can be used to improve outcomes after common surgical procedures. ..
  62. Incidence & Outcomes of SSI After Breast Cancer Surgery
    Margaret Olsen; Fiscal Year: 2007
    ....
  63. Vascular Healing with VEGF-Collagen Binding Chimera
    Luke Brewster; Fiscal Year: 2005
    ..Future promise for VEGFCBD may apply to intimal healing, surface endothelialization, and capillarization of and engineered tissues. ..
  64. Mechanism of Cognitive Dysfunction: CEA and Stenting
    ERIC HEYER; Fiscal Year: 2008
    ....
  65. Tissue Engineering Utilizing BMP Gene Therapy
    GREGORY HELM; Fiscal Year: 2003
    ....
  66. Neuropsychological Outcome of Carotid Endarterectomy
    ERIC HEYER; Fiscal Year: 2003
    ..EEG is inadequate to determine this subtle degree of hypoperfusion. ..
  67. Catastrophizing and Pain in Rheumatoid Arthritis
    Robert Edwards; Fiscal Year: 2008
    ..abstract_text> ..