diskectomy

..Description of rationale and design of PROCON trial and discussion of its strengths and limitations...

..Eleven (19.6%) of the 56 patients did not respond to a satisfaction questionnaire. Outpatient ACDF has high patient satisfaction but does not compromise patient safety...

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..The significance of implant subsidence in acceleration of degenerative changes in adjacent segments remains to be evaluated during a longer follow-up...

..Cervical total disc replacement (TDR) is intended to address radicular pain and preserve functional motion between two vertebral bodies in patients with symptomatic cervical disc disease (SCDD)...

..The authors conducted a metaanalysis of studies published after 1990 in which fusion rates achieved with each procedure were reported for patients with degenerative disease at one, two, and three disc levels...

..3% in group B, and 84.85% in group C. The fusion rates after 1 year in groups A, B, and C were 46.51%, 100% and 100%, respectively. The PEEK cage is a viable alternative to autogenous tricortical bone grafts in anterior cervical fusion...

..A Cochrane review of randomized controlled trials...

..Cochrane systematic review of randomized controlled trials...

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..In addition, the influence of the extent of disc resection (unilateral/bilateral removal) and the side of operation on static balance control were investigated...

..A prospective study was performed in case with cervical spondylosis who underwent anterior cervical discectomy and fusion (ACDF) with titanium or polyetheretherketone (PEEK) cages...

..Clinical and radiologic study evaluating the outcome after anterior corpectomy with iliac bone fusion compared with discectomy with interbody titanium cage fusion for multilevel cervical degenerated disc disease...

..CONCLUSION: Three-level anterior cervical discectomy with plate fixation has a high rate of fusion, a low complication rate, and acceptable outcome in the treatment of multilevel cervical spondylosis...

Recurrent lumbar disk herniation is the most common complication following primary open diskectomy. It is defined as recurrent back and/or leg pain after a definite pain-free period lasting at least 6 months from initial surgery...

..In the opinion, pseudoarthrosis is caused by malpositioning of the carbon fiber cage...

..The minority of patients experience moderate or severe symptoms by 6 months after the procedure. Female gender and multiple surgical levels could be identified as risk factors for the development of postoperative dysphagia...

..The improved fusion rate and negligible complication rate associated with anterior cervical plating are compelling factors justifying its use in the treatment of cervical spondylosis...

..The authors use the methodology and data derived from their study to evaluate critically the relevance of these two categories of success rates...

..Although there was no significant difference in a short-term clinical result between the two treatment groups, we recommend the use of cages which preserve the determined segmental height and lordosis...

..The aim of this prospective study was to evaluate subsidence and total segmental height after implantation of a newly designed Wing titanium cage. Furthermore, alignment of the entire cervical spine was analyzed 2 years after surgery...

..One of these devices is the titanium Rabea cage (Signus, Alzenau, Germany) [correction]. There are no peer-reviewed objective reports on the use of these cages in cervical discectomy...

..A retrospective review of all patients surgically treated by a single surgeon with a three-level anterior cervical discectomy and fusion with and without anterior plate fixation...

..A review of 66 consecutive patients at a single institution who underwent one-level anterior cervical discectomy and fusion (ACDF) with rigid anterior plate fixation with allograft or autograft...

..However, PEEK cage is preferred in our study for multilevel fusion, because it has the fewest complication rates and the least amount of blood loss...

..The authors believe that the measurement of distances between spinous processes on lateral flexion-extension radiographs should be used as a method for evaluating radiographic fusion in patients with pseudarthrosis...

..The study showed that microendoscopic discectomy allows a smaller incision and less tissue trauma with comparable visualization of the nerve structures than does open surgery...

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..The purpose of the current study was to address the outcome in the patients who had recurrent disc herniation treated with repeat discectomy and to identify the factors that may influence the outcome...

..j.a.)...

..Based on these results, the polymeric biomaterial PEEK may be a useful biomaterial for interbody fusion cages due to the polymer's increased radiolucency and decreased stiffness...

..More extensive surgery does not prevent nor predispose a patient to the need for further surgery...

..To date no published data exist in the English literature upon which to judge symptomatic patients (experiencing postoperative airway distress) radiographically...

..Prospectively collected data from regular clinical follow-up evaluations were tabulated, analyzed, reviewed using a patient self-reported questionnaire...

..Results were similar in terms of complications and clinical outcome. As the PMMA surgery took longer and the costs of titanium are higher, there is no marked advantage of one implant material over the other...

..Reports specifically describing minimally invasive surgical approaches to lumbosacral ELDHs are lacking...

..The aim of this study was to determine the efficacy of dynamic lumbar stabilization exercises in patients with lumbar microdiscectomy...

The incidence of symptomatic adjacent segment disease (ASD) after anterior cervical diskectomy and fusion (ACDF) was reported as 2.9%/y in a previous cohort of 374 patients...

..Intracanal and extracanal herniations, reherniations, and incidental lateral recess stenosis can be addressed by the same approach...

..In agreement with the literature, our results confirm the negative role of depression in outcome after lumbar disc surgery. We emphasize the consideration of psychological factors in the management of lumbar disc herniation...

..1%). In conclusion, in this prospective study of 87 patients fused at one or two levels in the cervical spine peak prevertebral soft tissue swelling was observed on the second and third days after the surgery...

..Despite functional morbidity and legal implications, the incidence and etiologic factors of these complications have not been adequately elucidated...

..Extraforaminal disc herniation can be diagnosed with the aid of CT scan and MRI. The minimally invasive surgical treatment via the micro-endoscopic far lateral approach, in our initial experience, has a high rate of succes...

..The technique allows a smaller incision and less tissue trauma with comparable visualization of the nerve structures than does standard open surgery...

..No conclusions could be drawn from the clinical randomised studies reviewed regarding the safety of the three techniques studied due to insufficient data on postoperative complications...

..The Bryan disc preserves motion of the FSU. Although the preoperative lordosis (or kyphosis) of the FSU could not always be maintained during the follow-up period, the overall sagittal balance of the cervical spine was usually preserved...

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..A surgical treatment of dysphagia after ACIF has not been reported...

..6%) of the 63 patients. CONCLUSIONS: The autograft cancellous bone-filled PMMA cage is safe and effective for cervical interbody fusion in the treatment of single-level cervical disc herniation and monoradiculopathy...

..33% per year). - In conclusion PMMA is still the most widely used spacer material after anterior cervical discectomy in Germany. An increased complication rate in comparison with other implants could not be observed...

..Volume-related stiffness of all cages was higher than that of iliac bone graft. The Harms cage was highest in volume-related stiffness in all directions. The HCIFC can provide enough primary stability for cervical intervertebral fusion...

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..The authors evaluate the effects of implantation of a carbon fiber cage after anterior cervical discectomy (ACD) on the height of the foramen and the angulation between endplates of the disc space...

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..To their knowledge, this prospective study is the first in which foraminal height changes over time are compared following the placement of a tricortical graft or a polyetheretherketone (PEEK) cage...

..Analysis of the results indicated the cancellous allograft bone-filled PEEK cage used in ACDF is a good choice for patients with cervical disc disease, and avoids the complications of harvesting iliac autograft...

..CONCLUSIONS: Although the rate of surgery for cervical disc disease did not increase significantly during the 1990s, the rate of fusion procedures did rise significantly...

..CONCLUSIONS: Early experience with Solis cage-augmented ACDF indicates good clinical and radiological outcomes; additionally, there are the advantages of absent donor site morbidity and anterior plate system-related morbidity...

..The purpose of this study was to assess feasibility, safety, and preliminary clinical results of percutaneous plasma-mediated radio-frequency-based diskectomy for cervical disk herniation.

..Pain scores, serum creatine phosphokinase (CPK) levels, and histological findings obtained in muscle specimens were compared...

..Recurrent herniation of the nucleus pulposus (HNP) frequently causes poor outcomes after lumbar discectomy. The relationship between obesity and recurrent HNP has not previously been reported...

..An in vitro biomechanical study of cervical spine interbody fusion cages using a sheep model was conducted...

..Three-dimensional, nonlinear finite element models were used to evaluate the stability of the mid cervical spine after anterior fusion in patients with and without osteoporosis...

..The impact of minimally invasive spinal (MIS) surgery on the incidence of perioperative adverse events in overweight or obese patients, however, has not been well evaluated...

..CONCLUSION: Open and thoracoscopic anterior release and discectomy have been demonstrated, through biomechanical in vitro testing, to increase the flexibility of the spine to a similar extent...

..These results should be interpreted cautiously, because surgical treatment was not assigned randomly. Long-term follow-up will determine if these differences persist...

..An updated Cochrane Review...

..Retrospective review study with literature review...

..A retrospective, follow-up study...

..13). CONCLUSIONS: Achieving fusion is more difficult when anterior cervical arthrodesis is performed adjacent to a prior fusion. Strut grafting resulted in a significantly higher rate of arthrodesis than interbody grafting...

..In comparison, the conventional method resulted in a net loss of overall lordosis and segmental lordosis at the surgical site...

..In the current review, the requirements, achievements and challenges in this quickly emerging field of research are discussed...

..Great care is taken to identify the osseous margins of the previous surgical site. Identification and dissection of scar from the dura mater is greatly aided with the use of a microscope...

..MR imaging is essential to achieve the correct differential diagnosis...

..If pain exists it does not last very long. Generally, the pain is resolved within 2 weeks...

..Therefore, the objective of this study was to compare early outcome and recurrence rates after sequestrectomy and microdiscectomy...

..The relevant literature is reviewed. CONCLUSIONS: This case illustrates the possible consequences of not repairing a dural tear and reinforces the importance of a careful surgical approach to the lumbar spine...

..This paper examines a single-surgeon experience with single-level ACDF without use of plates or hard collars in patients with degenerative spondylosis in whom allograft was used as the fusion material...

..However, patients must be cautioned that recurrent symptoms can occur, and, in a small percentage of patients, the symptoms may be severe enough to require additional surgery...

..05). Cervical spine disc prosthesis preserves cervical spine segmental motion within the first 6 months after surgery. The clinical results are the same when compared to the early results following ACDF...

..Retrospective cohort study...

..To retrospectively evaluate if the degree of disk degeneration and disk herniation volume at magnetic resonance (MR) imaging are risk factors for recurrent disk herniation...

..A prospective randomized controlled study was carried out...

..Clinical outcomes are comparable to those of other forms of discectomy...

..Anterior cervical plating significantly increased biomechanical stability in all modes...

..To assess the prognostic value of some preoperative and early post-operative indicators in the prediction of disability 14 months after lumbar disc surgery...

..This study examines the long-term follow up and satisfaction level of patients who underwent microlumbar discectomy as an outpatient procedure...

..Patients undergoing multilevel procedures are at an increased risk for these complications, in part because of soft tissue swelling in the neck...

..Surgical times, blood loss, complications, and outcome were similar to a traditional open microdiscectomy while pain medication requirements and hospitalization were significantly less...

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..Based on these results, the use of polymethylmethacrylate to obtain fusion after anterior discectomy is not recommended...

..We report our short-term experience with the use of the Wallis device in the management of patients with lumbar disc herniation undergoing primary disc excision...

..To study associations between pain, trunk muscle strength, flexibility and disability in patients with lumbar disc herniation 2 months after surgery...

..8% of the patients. Proper patient selection and meticulous operative technique is essential to obtain high fusion rates and optimal clinical outcome, which is more important than graft type...

..Prospective cohort study...

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..There are numerous types of disc prostheses and designs under study or in development. Well designed prospective RCTs are needed before approval and widespread application of this technology...

..For the present, it seems preferable to exclude the patient who already has significant segmental kyphosis from disc arthroplasty with Bryan Cervical Disc prosthesis...

..Postoperative kyphosis can be prevented by understanding the biomechanical properties of the Bryan disc. Future studies will need to address the association between postoperative kyphosis, clinical outcome and adjacent segment disease...

..Finally, patients with acute optic neuritis will be followed with behavioral and mVEP techniques. An attempt will be made to understand the recovery o vision following optic neuritis (ON). ..

..This could be especially valuable in assessing retinal function of patients with heterogeneous damage as in retinitis pigmentosa, diabetic retinopathy, and glaucoma. ..

..monkeys in which INL activity is pharmacologically dissected, b. normal human subjects, c. patients with disease of the INL, and d. mathematical work. ..

..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..

..The experiments under Aim 4 are designed to improve on the currently available methods of recording and analyzing the multifocal VEP. The aim is to improve the efficacy of the multifocal VEP technique in the clinic. ..

..We propose as part of aim 3 to improve our understanding of these relationships as well as to improve our analysis of visual field data. ..

..These same techniques can enable the ophthalmologist to monitor the health of these cells and, thus the effectiveness of alternative treatments. ..

..Thus, we propose to develop a model of the human ERG that encompasses the activity of the inner nuclear layer as well as the receptors...

..Finally, we intend to obtain a better understanding of the relative involvement of the rod and different cone mechanisms in retinitis pigmentosa and in progressive cone dystrophy...

..The data will be analyzed within the context of recent models of cone systems, models based on recent physiology...

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..The purpose of the Dartmouth NRSA program is to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the nation's biomedical and behavioral research agenda. ..

..Thus, successful achievement of the proposed research will provide essential information on TDR implant performance and on clinical outcomes, which are needed for informed health care decisions. ..

..The purpose of this proposed research is to examine the influence of mechanical degradation after implantation on the clinical performance of metal-backed acetabular components for total hip arthroplasty. ..

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..This study will provide important new information to determine the optimal timing and type of reconstructive surgery for women after mastectomy based on their underlying illnesses. ..

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..The objective of Phase I is to demonstrate that the device restores normal spine biomechanics (range of motion and stiffness) and is durable in fatigue testing. ..

..EEG is inadequate to determine this subtle degree of hypoperfusion. ..

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..It, therefore, can be used in molecular and cell biology research, as well as by clinicians in many fields, including pathology oncology, cardiology and the clinical neurosciences. ..

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..This study will provide important new information that can be used to improve outcomes after common surgical procedures. ..

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..Future promise for VEGFCBD may apply to intimal healing, surface endothelialization, and capillarization of and engineered tissues. ..